1T49A

Allosteric inhibition of protein tyrosine phosphatase 1b
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
282
structure length
282
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric inhibition of protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1t49A00
1ONYA 2VEYA 2I4HA 3I80A 4HJQA 3A5KA 1Q6SA 2C46A 2OC3A 1NNYA 1NO6A 1AAXA 2VEUA 4RKKA 1QXKA 4QBEA 2YDUA 1L8GA 2I75A 1PYNA 3H2XA 1EEOA 1U26A 3D42A 1XRIA 1L8KA 2CM7A 3NMEA 2F6ZA 1NL9A 2QBSA 4GRYA 2I3RA 3O3LA 1G1FA 3PS5A 1T48A 2M3VA 3S4OA 3QCLA 1OEOX 3ZV2A 2FJMA 4NYHA 4YR8B 1V3AA 3O5XA 1NWLA 1LYVA 5KA4A 5BZZA 1T49A 3F41A 2Y2FA 3RZ2A 4RHGA 1G7FA 3BLTA 1XXVA 2NT2A 2I1YA 2Q05A 3RO1A 2NTAA 2H04A 2P4DA 2F6VA 3BRHA 5KADA 3QCFA 3ZMPA 1YGUA 4RI4A 3QCHA 5KACA 3S3KA 1ZZWA 2I6OA 1PXHA 2JJDA 5KA3A 2AZRA 1PH0A 2F6FA 5MMZB 2QBPA 3V0GA 3GXGA 1WAXA 2QDCA 1YTSA 4BJOA 3V0HA 3EB1A 2HNPA 5AWXA 1C85A 3N0AA 1Q1MA 2RF6A 2I5XA 2VEXA 4WU3A 2B3OA 3OMHA 2DXPA 3QCNA 3RGOA 3QCGA 5KA0A 1YTNA 2CNHA 1GFYA 4IKCA 1VHRA 2H4KA 1KAKA 2HB1A 3D1OA 4HRFA 2F46A 1PTVA 2CNEA 1YPTA 3V0JA 4R30A 3QCKA 5KA2A 2FJNA 4QBWA 2SHPA 5LXQB 1NZ7A 1ECVA 3QKPA 1A5YA 3I7ZA 1C83A 4KYQA 1EENA 3D1QA 2GWOA 2PBNA 4H1OA 2B4SA 2OZ5A 3BM8A 2G6ZA 5KA9A 2QDPA 4WU2A 4RH9A 1PTUA 3MOZA 1ZC0A 3AWGA 2ESBA 4GS0A 1M3GA 5K25A 5EHPA 1YWFA 3ZM0A 1ONZA 4QUNA 4Z6BA 1D5RA 1XXPA 4GE6A 1I9SA 3O4UA 3QCBA 3MMJA 1C88A 2H02A 2ZMMA 2QBQA 4DGXA 2CJZA 1G4US 1OEMX 3SMEA 4JMJA 3OLRA 1YTWA 1T4JA 4TVVA 3QCMA 3QCCA 2F6TA 2F71A 1FPZA 2B4OA 2QCTA 5BUGA 3ZMQA 1R6HA 3S3EA 4J51A 1GWZA 3ZM1A 1U25A 3CWEA 1OEUA 1YFOA 5GTJA 1JF7A 3EU0A 3O4TA 2QEPA 4NNDA 2B07A 1I9TA 2G59A 2BIJA 3I36A 4S0GA 3V0IA 4AZ1A 2HY3A 4NX8A 1XBOA 1Q6MA 4R0TA 2CMAA 1I57A 3QCDA 3V0FA 3EMUA 5KABA 2VEVA 3M4UA 4HJPA 2HC1A 4YAAA 1P15A 3F9BA 3SR9A 2B49A 2WGPA 2Y96A 1YZ4A 4D3QA 4RI5A 5K9VA 2A8BA 2I6PA 3RGQA 2J16A 3GXHA 3MOWA 3S4EA 4ERCA 1PTYA 2I6IA 3QKQA 4QAPA 2QBRA 3F81A 2CNGA 1PA9A 1G4WR 2BZLA 4ZI4A 2NZ6A 2B4PA 3F99A 4WOHA 2BV5A 2F70A 2I4GA 2PSZA 4GRZA 2B4UA 5J8RA 1ZCKA 3ZM3A 3QCJA 2I4EA 4QUMA 1C86A 4OHDA 1MKPA 4NWFA 1BZJA 4KYRA 2C7SA 1YN9A 3V0DA 4DGPA 2R0BA 2BGEA 3D9CA 4OHHA 4NWGA 4PYHA 4JBCA 1X24A 4BPCA 3A5JA 2CMBA 1OETA 5K24A 2E0TA 5KA1A 5IBSA 3O4SA 2AHSA 1RPMA 3ZM2A 3BLUA 5K23A 2CMCA 4GWFA 3QCIA 1G1GA 2J16B 4PVGA 2PA5A 1U24A 5KA7A 1JLNA 2F6YA 1YGRA 3U96A 5KAAA 2HVLA 1FPRA 1Q6JA 3LJ8A 2GP0A 1J4XA 5I6VA 1C87A 2CM8A 2NT7A 4KI9A 4R0SA 3D44A 2Q47A 3S3HA 1OHEA 1Q6PA 1RXDA 2CFVA 2H4VA 4D3PA 1PTTA 1FQ1A 1WRMA 4Y14A 2IMGA 2CNIA 4OHEA 1G7GA 2MBCA 1Q6TA 2HNQA 2ZN7A 2HCMA 4WTYA 1SUGA 2NLKA 4Y2EA 2J17A 1KAVA 5EHRA 5KA8A 2I6JA 1BZCA 1G1HA 2BGDA 2A3KA 2HC2A 3EZZA 4ZN5A 3V0EA 2NV5A 4D3RA 3S3FA 2PI7A 2QDMA 2I3UA 4ZRTA 3B7OA 5BX1A 2F6WA 2I42A 4OHIA 2P6XA 4JNBA 5BZXA 4B04A 3D1HA 3F9AA 1OHDA 4MBBA 1LARA 4GFVA 4RH5A 1OESA 1BZHA 1C84A 1Q6NA 4JMKA 1OEVA 1LQFA 4GE5A 2CNFA 2VEWA 2OOQA 4GE2A 2PT0A 3CM3A 4GFUA 1ZCLA 5HDEA 2PQ5A 4H34A 4QAHA 2CM3A 1XM2A 1QZ0A 2H4GA 3AWEA 5K22A 1PA1A 1WCHA 5K9WA 2OUDA 2CM2A 4RDDA 2I6MA 2FH7A 2GJTA 2QCJA 2H03A 2HXPA 1NWEA 1OHCA 5IBMA 3EAXA 4OHLA 5M43A 3QCEA 4ICZA 4I8NA 3AWFA
chains in the Genus database with same CATH superfamily
1ONYA 2VEYA 2I4HA 3I80A 4HJQA 3A5KA 1Q6SA 2C46A 2OC3A 1NNYA 4QDIA 1NO6A 1AAXA 2VEUA 2VOSA 4RKKA 1QXKA 4QBEA 2YDUA 1L8GA 2I75A 1PYNA 3H2XA 1EEOA 1U26A 3D42A 1XRIA 1L8KA 2CM7A 4BUBA 3NMEA 2JFHA 2F6ZA 2GC6A 1NL9A 2QBSA 4GRYA 2I3RA 3O3LA 2GCBA 1G1FA 3PS5A 1T48A 2M3VA 3S4OA 3QCLA 1OEOX 3ZV2A 2FJMA 4NYHA 4YR8B 2X5OA 1GQYA 1V3AA 3O5XA 1NWLA 1LYVA 5KA4A 5BZZA 1T49A 3F41A 2Y2FA 3QCZA 3RZ2A 4RHGA 1G7FA 2Y1OA 3BLTA 1XXVA 2NT2A 2I1YA 2Q05A 3RO1A 1E0DA 2NTAA 2H04A 2P4DA 2F6VA 3BRHA 5KADA 4UAGA 4C13A 1UAGA 3LK7A 3QCFA 3ZMPA 1YGUA 5A5EA 2AM2A 3QCHA 4RI4A 1W7KA 5KACA 3S3KA 2JFGA 1ZZWA 2I6OA 1PXHA 2JJDA 5KA3A 2AZRA 1PH0A 2F6FA 5MMZB 2QBPA 3V0GA 3GXGA 1WAXA 2QDCA 1JBWA 1YTSA 4BJOA 3V0HA 3EB1A 2HNPA 5AWXA 1W78A 1C85A 3N0AA 2VEXA 1Q1MA 2I5XA 2RF6A 4WU3A 2B3OA 3OMHA 2DXPA 3QCNA 3RGOA 3QCGA 5KA0A 1YTNA 2JFFA 1P31A 2CNHA 1GFYA 4IKCA 3MVNA 1VHRA 2H4KA 1KAKA 2HB1A 3D1OA 4CVKA 4HRFA 2F46A 1PTVA 2CNEA 1YPTA 3V0JA 4R30A 2Y66A 3QCKA 5KA2A 2FJNA 4QBWA 2Y68A 2SHPA 5LXQB 1NZ7A 1ECVA 3QKPA 1A5YA 3I7ZA 1C83A 4KYQA 1EENA 2VTEA 2GWOA 2PBNA 2VORA 3D1QA 4H1OA 2B4SA 2OZ5A 3BM8A 2G6ZA 5KA9A 2QDPA 4WU2A 4RH9A 1PTUA 3MOZA 1ZC0A 3AWGA 2ESBA 4GS0A 1M3GA 5K25A 2UUOA 5EHPA 1YWFA 3ZM0A 1ONZA 4QUNA 4Z6BA 1D5RA 1XXPA 4GE6A 1I9SA 3O4UA 3QCBA 3MMJA 1C88A 2H02A 2ZMMA 2QBQA 4DGXA 2CJZA 1G4US 1OEMX 4HV4A 3SMEA 4JMJA 3OLRA 2Y67A 1YTWA 1T4JA 4TVVA 3QCMA 3QCCA 2F6TA 2F71A 4ZIYA 1FPZA 2B4OA 2QCTA 4CVLA 5BUGA 4CVMA 3ZMQA 1JBVA 1R6HA 3S3EA 4J51A 1GWZA 3ZM1A 1U25A 3CWEA 1OEUA 1YFOA 5GTJA 1JF7A 3EU0A 3O4TA 2QEPA 4NNDA 2B07A 1I9TA 2G59A 2BIJA 3I36A 4S0GA 3V0IA 4AZ1A 2HY3A 2XJAA 4NX8A 1XBOA 1Q6MA 2F00A 4R0TA 2CMAA 3ZL8A 1I57A 3QCDA 3V0FA 3EMUA 5KABA 2GCAA 2VEVA 3M4UA 4HJPA 2HC1A 4YAAA 1P15A 3F9BA 3SR9A 2B49A 2WGPA 2Y96A 1YZ4A 4D3QA 4RI5A 5K9VA 2A8BA 2I6PA 3RGQA 2J16A 3GXHA 3MOWA 3S4EA 4ERCA 1PTYA 2I6IA 3PYZA 3QKQA 4QAPA 1E8CA 2QBRA 3F81A 2CNGA 1PA9A 1G4WR 2BZLA 4ZI4A 2NZ6A 2B4PA 3F99A 4WOHA 2BV5A 2F70A 2I4GA 2PSZA 4GRZA 2B4UA 5J8RA 3N2AA 1ZCKA 2AM1A 3ZM3A 3QCJA 2I4EA 4QUMA 1C86A 4OHDA 1MKPA 4NWFA 1BZJA 4KYRA 2C7SA 3ZM6A 1YN9A 3V0DA 4DGPA 2R0BA 2BGEA 3D9CA 2GC5A 4OHHA 4NWGA 4PYHA 3UAGA 3NRSA 4JBCA 1X24A 1O5ZA 4BPCA 3A5JA 2CMBA 1OETA 5K24A 2E0TA 1GG4A 5KA1A 5IBSA 3O4SA 2AHSA 1RPMA 3ZM2A 3BLUA 5K23A 2CMCA 4GWFA 3QCIA 1G1GA 2XPCA 2J16B 4PVGA 2PA5A 1U24A 5KA7A 1JLNA 2F6YA 1YGRA 3U96A 5KAAA 2HVLA 1FPRA 1Q6JA 3LJ8A 2GP0A 1J4XA 5I6VA 1C87A 2WTZA 2CM8A 2NT7A 4KI9A 4R0SA 3D44A 2Q47A 3S3HA 1OHEA 1Q6PA 1RXDA 2CFVA 2H4VA 1GQQA 4D3PA 1PTTA 1FQ1A 1WRMA 4Y14A 2IMGA 2CNIA 2VTDA 4OHEA 1G7GA 2MBCA 1Q6TA 2HNQA 2ZN7A 2HCMA 4WTYA 1SUGA 2NLKA 4Y2EA 2J17A 1KAVA 5EHRA 5KA8A 2I6JA 1BZCA 1G1HA 2BGDA 2A3KA 2HC2A 3EZZA 4ZN5A 3V0EA 2NV5A 4D3RA 3S3FA 2PI7A 4BUCA 2QDMA 2I3UA 4ZRTA 3B7OA 5BX1A 2F6WA 2I42A 4OHIA 2P6XA 4JNBA 5BZXA 4B04A 3D1HA 3F9AA 4C12A 1OHDA 4MBBA 1LARA 4GFVA 4RH5A 1OESA 2UUPA 1BZHA 1C84A 1Q6NA 4JMKA 1OEVA 1LQFA 4GE5A 2CNFA 2VEWA 2OOQA 3HN7A 4GE2A 2PT0A 3CM3A 3ZM5A 4GFUA 1P3DA 5A5FA 1J6UA 1ZCLA 5HDEA 2PQ5A 4H34A 4QAHA 2CM3A 1XM2A 1QZ0A 4QF5A 2H4GA 1EEHA 2WJPA 3AWEA 5K22A 1PA1A 1WCHA 5K9WA 2OUDA 2CM2A 4RDDA 2I6MA 1FGSA 2FH7A 2GJTA 2H03A 2HXPA 2QCJA 1NWEA 1OHCA 5IBMA 3EAXA 4OHLA 5M43A 3QCEA 2UAGA 4ICZA 4I8NA 3AWFA
chains in the Genus database with same CATH topology
1ONYA 2VEYA 2I4HA 3I80A 4HJQA 3A5KA 1Q6SA 2C46A 2OC3A 1NNYA 1NO6A 1AAXA 2VEUA 4RKKA 1QXKA 4QBEA 2YDUA 1L8GA 2I75A 1PYNA 3H2XA 1EEOA 1U26A 3D42A 1XRIA 1L8KA 2CM7A 3NMEA 2F6ZA 1NL9A 2QBSA 4GRYA 2I3RA 3O3LA 1G1FA 3PS5A 1T48A 2M3VA 3S4OA 3QCLA 1OEOX 3ZV2A 2FJMA 4NYHA 4YR8B 1V3AA 3O5XA 1NWLA 1LYVA 5KA4A 5BZZA 1T49A 3F41A 2Y2FA 3RZ2A 4RHGA 1G7FA 3BLTA 1XXVA 2NT2A 2I1YA 2Q05A 3RO1A 2NTAA 2H04A 2P4DA 2F6VA 3BRHA 5KADA 3QCFA 3ZMPA 1YGUA 4RI4A 3QCHA 5KACA 3S3KA 1ZZWA 2I6OA 1PXHA 2JJDA 5KA3A 2AZRA 1PH0A 2F6FA 5MMZB 2QBPA 3V0GA 3GXGA 1WAXA 2QDCA 1YTSA 4BJOA 3V0HA 3EB1A 2HNPA 5AWXA 1C85A 3N0AA 1Q1MA 2RF6A 2I5XA 2VEXA 4WU3A 2B3OA 3OMHA 2DXPA 3QCNA 3RGOA 3QCGA 5KA0A 1YTNA 2CNHA 1GFYA 4IKCA 1VHRA 2H4KA 1KAKA 2HB1A 3D1OA 4HRFA 2F46A 1PTVA 2CNEA 1YPTA 3V0JA 4R30A 3QCKA 5KA2A 2FJNA 4QBWA 2SHPA 5LXQB 1NZ7A 1ECVA 3QKPA 1A5YA 3I7ZA 1C83A 4KYQA 1EENA 3D1QA 2GWOA 2PBNA 4H1OA 2B4SA 2OZ5A 3BM8A 2G6ZA 5KA9A 2QDPA 4WU2A 4RH9A 1PTUA 3MOZA 1ZC0A 3AWGA 2ESBA 4GS0A 1M3GA 5K25A 5EHPA 1YWFA 3ZM0A 1ONZA 4QUNA 4Z6BA 1D5RA 1XXPA 4GE6A 1I9SA 3O4UA 3QCBA 3MMJA 1C88A 2H02A 2ZMMA 2QBQA 4DGXA 2CJZA 1G4US 1OEMX 3SMEA 4JMJA 3OLRA 1YTWA 1T4JA 4TVVA 3QCMA 3QCCA 2F6TA 2F71A 1FPZA 2B4OA 2QCTA 5BUGA 3ZMQA 1R6HA 3S3EA 4J51A 1GWZA 3ZM1A 1U25A 3CWEA 1OEUA 1YFOA 5GTJA 1JF7A 3EU0A 3O4TA 2QEPA 4NNDA 2B07A 1I9TA 2G59A 2BIJA 3I36A 4S0GA 3V0IA 4AZ1A 2HY3A 4NX8A 1XBOA 1Q6MA 4R0TA 2CMAA 1I57A 3QCDA 3V0FA 3EMUA 5KABA 2VEVA 3M4UA 4HJPA 2HC1A 4YAAA 1P15A 3F9BA 3SR9A 2B49A 2WGPA 2Y96A 1YZ4A 4D3QA 4RI5A 5K9VA 2A8BA 2I6PA 3RGQA 2J16A 3GXHA 3MOWA 3S4EA 4ERCA 1PTYA 2I6IA 3QKQA 4QAPA 2QBRA 3F81A 2CNGA 1PA9A 1G4WR 2BZLA 4ZI4A 2NZ6A 2B4PA 3F99A 4WOHA 2BV5A 2F70A 2I4GA 2PSZA 4GRZA 2B4UA 5J8RA 1ZCKA 3ZM3A 3QCJA 2I4EA 4QUMA 1C86A 4OHDA 1MKPA 4NWFA 1BZJA 4KYRA 2C7SA 1YN9A 3V0DA 4DGPA 2R0BA 2BGEA 3D9CA 4OHHA 4NWGA 4PYHA 4JBCA 1X24A 4BPCA 3A5JA 2CMBA 1OETA 5K24A 2E0TA 5KA1A 5IBSA 3O4SA 2AHSA 1RPMA 3ZM2A 3BLUA 5K23A 2CMCA 4GWFA 3QCIA 1G1GA 2J16B 4PVGA 2PA5A 1U24A 5KA7A 1JLNA 2F6YA 1YGRA 3U96A 5KAAA 2HVLA 1FPRA 1Q6JA 3LJ8A 2GP0A 1J4XA 5I6VA 1C87A 2CM8A 2NT7A 4KI9A 4R0SA 3D44A 2Q47A 3S3HA 1OHEA 1Q6PA 1RXDA 2CFVA 2H4VA 4D3PA 1PTTA 1FQ1A 1WRMA 4Y14A 2IMGA 2CNIA 4OHEA 1G7GA 2MBCA 1Q6TA 2HNQA 2ZN7A 2HCMA 4WTYA 1SUGA 2NLKA 4Y2EA 2J17A 1KAVA 5EHRA 5KA8A 2I6JA 1BZCA 1G1HA 2BGDA 2A3KA 2HC2A 3EZZA 4ZN5A 3V0EA 2NV5A 4D3RA 3S3FA 2PI7A 2QDMA 2I3UA 4ZRTA 3B7OA 5BX1A 2F6WA 2I42A 4OHIA 2P6XA 4JNBA 5BZXA 4B04A 3D1HA 3F9AA 1OHDA 4MBBA 1LARA 4GFVA 4RH5A 1OESA 1BZHA 1C84A 1Q6NA 4JMKA 1OEVA 1LQFA 4GE5A 2CNFA 2VEWA 2OOQA 4GE2A 2PT0A 3CM3A 4GFUA 1ZCLA 5HDEA 2PQ5A 4H34A 4QAHA 2CM3A 1XM2A 1QZ0A 2H4GA 3AWEA 5K22A 1PA1A 1WCHA 5K9WA 2OUDA 2CM2A 4RDDA 2I6MA 2FH7A 2GJTA 2QCJA 2H03A 2HXPA 1NWEA 1OHCA 5IBMA 3EAXA 4OHLA 5M43A 3QCEA 4ICZA 4I8NA 3AWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ONY A;  2VEY A;  2I4H A;  3I80 A;  4HJQ A;  3A5K A;  1Q6S A;  2C46 A;  2OC3 A;  1NNY A;  1NO6 A;  1AAX A;  2VEU A;  4RKK A;  1QXK A;  4QBE A;  2YDU A;  1L8G A;  2I75 A;  1PYN A;  3H2X A;  1EEO A;  1U26 A;  3D42 A;  1XRI A;  1L8K A;  2CM7 A;  3NME A;  2F6Z A;  1NL9 A;  2QBS A;  4GRY A;  2I3R A;  3O3L A;  1G1F A;  3PS5 A;  1T48 A;  2M3V A;  3S4O A;  3QCL A;  1OEO X;  3ZV2 A;  2FJM A;  4NYH A;  4YR8 B;  1V3A A;  3O5X A;  1NWL A;  1LYV A;  5KA4 A;  5BZZ A;  1T49 A;  3F41 A;  2Y2F A;  3RZ2 A;  4RHG A;  1G7F A;  3BLT A;  1XXV A;  2NT2 A;  2I1Y A;  2Q05 A;  3RO1 A;  2NTA A;  2H04 A;  2P4D A;  2F6V A;  3BRH A;  5KAD A;  3QCF A;  3ZMP A;  1YGU A;  4RI4 A;  3QCH A;  5KAC A;  3S3K A;  1ZZW A;  2I6O A;  1PXH A;  2JJD A;  5KA3 A;  2AZR A;  1PH0 A;  2F6F A;  5MMZ B;  2QBP A;  3V0G A;  3GXG A;  1WAX A;  2QDC A;  1YTS A;  4BJO A;  3V0H A;  3EB1 A;  2HNP A;  5AWX A;  1C85 A;  3N0A A;  1Q1M A;  2RF6 A;  2I5X A;  2VEX A;  4WU3 A;  2B3O A;  3OMH A;  2DXP A;  3QCN A;  3RGO A;  3QCG A;  5KA0 A;  1YTN A;  2CNH A;  1GFY A;  4IKC A;  1VHR A;  2H4K A;  1KAK A;  2HB1 A;  3D1O A;  4HRF A;  2F46 A;  1PTV A;  2CNE A;  1YPT A;  3V0J A;  4R30 A;  3QCK A;  5KA2 A;  2FJN A;  4QBW A;  2SHP A;  5LXQ B;  1NZ7 A;  1ECV A;  3QKP A;  1A5Y A;  3I7Z A;  1C83 A;  4KYQ A;  1EEN A;  3D1Q A;  2GWO A;  2PBN A;  4H1O A;  2B4S A;  2OZ5 A;  3BM8 A;  2G6Z A;  5KA9 A;  2QDP A;  4WU2 A;  4RH9 A;  1PTU A;  3MOZ A;  1ZC0 A;  3AWG A;  2ESB A;  4GS0 A;  1M3G A;  5K25 A;  5EHP A;  1YWF A;  3ZM0 A;  1ONZ A;  4QUN A;  4Z6B A;  1D5R A;  1XXP A;  4GE6 A;  1I9S A;  3O4U A;  3QCB A;  3MMJ A;  1C88 A;  2H02 A;  2ZMM A;  2QBQ A;  4DGX A;  2CJZ A;  1G4U S;  1OEM X;  3SME A;  4JMJ A;  3OLR A;  1YTW A;  1T4J A;  4TVV A;  3QCM A;  3QCC A;  2F6T A;  2F71 A;  1FPZ A;  2B4O A;  2QCT A;  5BUG A;  3ZMQ A;  1R6H A;  3S3E A;  4J51 A;  1GWZ A;  3ZM1 A;  1U25 A;  3CWE A;  1OEU A;  1YFO A;  5GTJ A;  1JF7 A;  3EU0 A;  3O4T A;  2QEP A;  4NND A;  2B07 A;  1I9T A;  2G59 A;  2BIJ A;  3I36 A;  4S0G A;  3V0I A;  4AZ1 A;  2HY3 A;  4NX8 A;  1XBO A;  1Q6M A;  4R0T A;  2CMA A;  1I57 A;  3QCD A;  3V0F A;  3EMU A;  5KAB A;  2VEV A;  3M4U A;  4HJP A;  2HC1 A;  4YAA A;  1P15 A;  3F9B A;  3SR9 A;  2B49 A;  2WGP A;  2Y96 A;  1YZ4 A;  4D3Q A;  4RI5 A;  5K9V A;  2A8B A;  2I6P A;  3RGQ A;  2J16 A;  3GXH A;  3MOW A;  3S4E A;  4ERC A;  1PTY A;  2I6I A;  3QKQ A;  4QAP A;  2QBR A;  3F81 A;  2CNG A;  1PA9 A;  1G4W R;  2BZL A;  4ZI4 A;  2NZ6 A;  2B4P A;  3F99 A;  4WOH A;  2BV5 A;  2F70 A;  2I4G A;  2PSZ A;  4GRZ A;  2B4U A;  5J8R A;  1ZCK A;  3ZM3 A;  3QCJ A;  2I4E A;  4QUM A;  1C86 A;  4OHD A;  1MKP A;  4NWF A;  1BZJ A;  4KYR A;  2C7S A;  1YN9 A;  3V0D A;  4DGP A;  2R0B A;  2BGE A;  3D9C A;  4OHH A;  4NWG A;  4PYH A;  4JBC A;  1X24 A;  4BPC A;  3A5J A;  2CMB A;  1OET A;  5K24 A;  2E0T A;  5KA1 A;  5IBS A;  3O4S A;  2AHS A;  1RPM A;  3ZM2 A;  3BLU A;  5K23 A;  2CMC A;  4GWF A;  3QCI A;  1G1G A;  2J16 B;  4PVG A;  2PA5 A;  1U24 A;  5KA7 A;  1JLN A;  2F6Y A;  1YGR A;  3U96 A;  5KAA A;  2HVL A;  1FPR A;  1Q6J A;  3LJ8 A;  2GP0 A;  1J4X A;  5I6V A;  1C87 A;  2CM8 A;  2NT7 A;  4KI9 A;  4R0S A;  3D44 A;  2Q47 A;  3S3H A;  1OHE A;  1Q6P A;  1RXD A;  2CFV A;  2H4V A;  4D3P A;  1PTT A;  1FQ1 A;  1WRM A;  4Y14 A;  2IMG A;  2CNI A;  4OHE A;  1G7G A;  2MBC A;  1Q6T A;  2HNQ A;  2ZN7 A;  2HCM A;  4WTY A;  1SUG A;  2NLK A;  4Y2E A;  2J17 A;  1KAV A;  5EHR A;  5KA8 A;  2I6J A;  1BZC A;  1G1H A;  2BGD A;  2A3K A;  2HC2 A;  3EZZ A;  4ZN5 A;  3V0E A;  2NV5 A;  4D3R A;  3S3F A;  2PI7 A;  2QDM A;  2I3U A;  4ZRT A;  3B7O A;  5BX1 A;  2F6W A;  2I42 A;  4OHI A;  2P6X A;  4JNB A;  5BZX A;  4B04 A;  3D1H A;  3F9A A;  1OHD A;  4MBB A;  1LAR A;  4GFV A;  4RH5 A;  1OES A;  1BZH A;  1C84 A;  1Q6N A;  4JMK A;  1OEV A;  1LQF A;  4GE5 A;  2CNF A;  2VEW A;  2OOQ A;  4GE2 A;  2PT0 A;  3CM3 A;  4GFU A;  1ZCL A;  5HDE A;  2PQ5 A;  4H34 A;  4QAH A;  2CM3 A;  1XM2 A;  1QZ0 A;  2H4G A;  3AWE A;  5K22 A;  1PA1 A;  1WCH A;  5K9W A;  2OUD A;  2CM2 A;  4RDD A;  2I6M A;  2FH7 A;  2GJT A;  2QCJ A;  2H03 A;  2HXP A;  1NWE A;  1OHC A;  5IBM A;  3EAX A;  4OHL A;  5M43 A;  3QCE A;  4ICZ A;  4I8N A;  3AWF A; 
#chains in the Genus database with same CATH topology
 1ONY A;  2VEY A;  2I4H A;  3I80 A;  4HJQ A;  3A5K A;  1Q6S A;  2C46 A;  2OC3 A;  1NNY A;  4QDI A;  1NO6 A;  1AAX A;  2VEU A;  2VOS A;  4RKK A;  1QXK A;  4QBE A;  2YDU A;  1L8G A;  2I75 A;  1PYN A;  3H2X A;  1EEO A;  1U26 A;  3D42 A;  1XRI A;  1L8K A;  2CM7 A;  4BUB A;  3NME A;  2JFH A;  2F6Z A;  2GC6 A;  1NL9 A;  2QBS A;  4GRY A;  2I3R A;  3O3L A;  2GCB A;  1G1F A;  3PS5 A;  1T48 A;  2M3V A;  3S4O A;  3QCL A;  1OEO X;  3ZV2 A;  2FJM A;  4NYH A;  4YR8 B;  2X5O A;  1GQY A;  1V3A A;  3O5X A;  1NWL A;  1LYV A;  5KA4 A;  5BZZ A;  1T49 A;  3F41 A;  2Y2F A;  3QCZ A;  3RZ2 A;  4RHG A;  1G7F A;  2Y1O A;  3BLT A;  1XXV A;  2NT2 A;  2I1Y A;  2Q05 A;  3RO1 A;  1E0D A;  2NTA A;  2H04 A;  2P4D A;  2F6V A;  3BRH A;  5KAD A;  4UAG A;  4C13 A;  1UAG A;  3LK7 A;  3QCF A;  3ZMP A;  1YGU A;  5A5E A;  2AM2 A;  3QCH A;  4RI4 A;  1W7K A;  5KAC A;  3S3K A;  2JFG A;  1ZZW A;  2I6O A;  1PXH A;  2JJD A;  5KA3 A;  2AZR A;  1PH0 A;  2F6F A;  5MMZ B;  2QBP A;  3V0G A;  3GXG A;  1WAX A;  2QDC A;  1JBW A;  1YTS A;  4BJO A;  3V0H A;  3EB1 A;  2HNP A;  5AWX A;  1W78 A;  1C85 A;  3N0A A;  2VEX A;  1Q1M A;  2I5X A;  2RF6 A;  4WU3 A;  2B3O A;  3OMH A;  2DXP A;  3QCN A;  3RGO A;  3QCG A;  5KA0 A;  1YTN A;  2JFF A;  1P31 A;  2CNH A;  1GFY A;  4IKC A;  3MVN A;  1VHR A;  2H4K A;  1KAK A;  2HB1 A;  3D1O A;  4CVK A;  4HRF A;  2F46 A;  1PTV A;  2CNE A;  1YPT A;  3V0J A;  4R30 A;  2Y66 A;  3QCK A;  5KA2 A;  2FJN A;  4QBW A;  2Y68 A;  2SHP A;  5LXQ B;  1NZ7 A;  1ECV A;  3QKP A;  1A5Y A;  3I7Z A;  1C83 A;  4KYQ A;  1EEN A;  2VTE A;  2GWO A;  2PBN A;  2VOR A;  3D1Q A;  4H1O A;  2B4S A;  2OZ5 A;  3BM8 A;  2G6Z A;  5KA9 A;  2QDP A;  4WU2 A;  4RH9 A;  1PTU A;  3MOZ A;  1ZC0 A;  3AWG A;  2ESB A;  4GS0 A;  1M3G A;  5K25 A;  2UUO A;  5EHP A;  1YWF A;  3ZM0 A;  1ONZ A;  4QUN A;  4Z6B A;  1D5R A;  1XXP A;  4GE6 A;  1I9S A;  3O4U A;  3QCB A;  3MMJ A;  1C88 A;  2H02 A;  2ZMM A;  2QBQ A;  4DGX A;  2CJZ A;  1G4U S;  1OEM X;  4HV4 A;  3SME A;  4JMJ A;  3OLR A;  2Y67 A;  1YTW A;  1T4J A;  4TVV A;  3QCM A;  3QCC A;  2F6T A;  2F71 A;  4ZIY A;  1FPZ A;  2B4O A;  2QCT A;  4CVL A;  5BUG A;  4CVM A;  3ZMQ A;  1JBV A;  1R6H A;  3S3E A;  4J51 A;  1GWZ A;  3ZM1 A;  1U25 A;  3CWE A;  1OEU A;  1YFO A;  5GTJ A;  1JF7 A;  3EU0 A;  3O4T A;  2QEP A;  4NND A;  2B07 A;  1I9T A;  2G59 A;  2BIJ A;  3I36 A;  4S0G A;  3V0I A;  4AZ1 A;  2HY3 A;  2XJA A;  4NX8 A;  1XBO A;  1Q6M A;  2F00 A;  4R0T A;  2CMA A;  3ZL8 A;  1I57 A;  3QCD A;  3V0F A;  3EMU A;  5KAB A;  2GCA A;  2VEV A;  3M4U A;  4HJP A;  2HC1 A;  4YAA A;  1P15 A;  3F9B A;  3SR9 A;  2B49 A;  2WGP A;  2Y96 A;  1YZ4 A;  4D3Q A;  4RI5 A;  5K9V A;  2A8B A;  2I6P A;  3RGQ A;  2J16 A;  3GXH A;  3MOW A;  3S4E A;  4ERC A;  1PTY A;  2I6I A;  3PYZ A;  3QKQ A;  4QAP A;  1E8C A;  2QBR A;  3F81 A;  2CNG A;  1PA9 A;  1G4W R;  2BZL A;  4ZI4 A;  2NZ6 A;  2B4P A;  3F99 A;  4WOH A;  2BV5 A;  2F70 A;  2I4G A;  2PSZ A;  4GRZ A;  2B4U A;  5J8R A;  3N2A A;  1ZCK A;  2AM1 A;  3ZM3 A;  3QCJ A;  2I4E A;  4QUM A;  1C86 A;  4OHD A;  1MKP A;  4NWF A;  1BZJ A;  4KYR A;  2C7S A;  3ZM6 A;  1YN9 A;  3V0D A;  4DGP A;  2R0B A;  2BGE A;  3D9C A;  2GC5 A;  4OHH A;  4NWG A;  4PYH A;  3UAG A;  3NRS A;  4JBC A;  1X24 A;  1O5Z A;  4BPC A;  3A5J A;  2CMB A;  1OET A;  5K24 A;  2E0T A;  1GG4 A;  5KA1 A;  5IBS A;  3O4S A;  2AHS A;  1RPM A;  3ZM2 A;  3BLU A;  5K23 A;  2CMC A;  4GWF A;  3QCI A;  1G1G A;  2XPC A;  2J16 B;  4PVG A;  2PA5 A;  1U24 A;  5KA7 A;  1JLN A;  2F6Y A;  1YGR A;  3U96 A;  5KAA A;  2HVL A;  1FPR A;  1Q6J A;  3LJ8 A;  2GP0 A;  1J4X A;  5I6V A;  1C87 A;  2WTZ A;  2CM8 A;  2NT7 A;  4KI9 A;  4R0S A;  3D44 A;  2Q47 A;  3S3H A;  1OHE A;  1Q6P A;  1RXD A;  2CFV A;  2H4V A;  1GQQ A;  4D3P A;  1PTT A;  1FQ1 A;  1WRM A;  4Y14 A;  2IMG A;  2CNI A;  2VTD A;  4OHE A;  1G7G A;  2MBC A;  1Q6T A;  2HNQ A;  2ZN7 A;  2HCM A;  4WTY A;  1SUG A;  2NLK A;  4Y2E A;  2J17 A;  1KAV A;  5EHR A;  5KA8 A;  2I6J A;  1BZC A;  1G1H A;  2BGD A;  2A3K A;  2HC2 A;  3EZZ A;  4ZN5 A;  3V0E A;  2NV5 A;  4D3R A;  3S3F A;  2PI7 A;  4BUC A;  2QDM A;  2I3U A;  4ZRT A;  3B7O A;  5BX1 A;  2F6W A;  2I42 A;  4OHI A;  2P6X A;  4JNB A;  5BZX A;  4B04 A;  3D1H A;  3F9A A;  4C12 A;  1OHD A;  4MBB A;  1LAR A;  4GFV A;  4RH5 A;  1OES A;  2UUP A;  1BZH A;  1C84 A;  1Q6N A;  4JMK A;  1OEV A;  1LQF A;  4GE5 A;  2CNF A;  2VEW A;  2OOQ A;  3HN7 A;  4GE2 A;  2PT0 A;  3CM3 A;  3ZM5 A;  4GFU A;  1P3D A;  5A5F A;  1J6U A;  1ZCL A;  5HDE A;  2PQ5 A;  4H34 A;  4QAH A;  2CM3 A;  1XM2 A;  1QZ0 A;  4QF5 A;  2H4G A;  1EEH A;  2WJP A;  3AWE A;  5K22 A;  1PA1 A;  1WCH A;  5K9W A;  2OUD A;  2CM2 A;  4RDD A;  2I6M A;  1FGS A;  2FH7 A;  2GJT A;  2H03 A;  2HXP A;  2QCJ A;  1NWE A;  1OHC A;  5IBM A;  3EAX A;  4OHL A;  5M43 A;  3QCE A;  2UAG A;  4ICZ A;  4I8N A;  3AWF A; 
#chains in the Genus database with same CATH homology
 1ONY A;  2VEY A;  2I4H A;  3I80 A;  4HJQ A;  3A5K A;  1Q6S A;  2C46 A;  2OC3 A;  1NNY A;  1NO6 A;  1AAX A;  2VEU A;  4RKK A;  1QXK A;  4QBE A;  2YDU A;  1L8G A;  2I75 A;  1PYN A;  3H2X A;  1EEO A;  1U26 A;  3D42 A;  1XRI A;  1L8K A;  2CM7 A;  3NME A;  2F6Z A;  1NL9 A;  2QBS A;  4GRY A;  2I3R A;  3O3L A;  1G1F A;  3PS5 A;  1T48 A;  2M3V A;  3S4O A;  3QCL A;  1OEO X;  3ZV2 A;  2FJM A;  4NYH A;  4YR8 B;  1V3A A;  3O5X A;  1NWL A;  1LYV A;  5KA4 A;  5BZZ A;  1T49 A;  3F41 A;  2Y2F A;  3RZ2 A;  4RHG A;  1G7F A;  3BLT A;  1XXV A;  2NT2 A;  2I1Y A;  2Q05 A;  3RO1 A;  2NTA A;  2H04 A;  2P4D A;  2F6V A;  3BRH A;  5KAD A;  3QCF A;  3ZMP A;  1YGU A;  4RI4 A;  3QCH A;  5KAC A;  3S3K A;  1ZZW A;  2I6O A;  1PXH A;  2JJD A;  5KA3 A;  2AZR A;  1PH0 A;  2F6F A;  5MMZ B;  2QBP A;  3V0G A;  3GXG A;  1WAX A;  2QDC A;  1YTS A;  4BJO A;  3V0H A;  3EB1 A;  2HNP A;  5AWX A;  1C85 A;  3N0A A;  1Q1M A;  2RF6 A;  2I5X A;  2VEX A;  4WU3 A;  2B3O A;  3OMH A;  2DXP A;  3QCN A;  3RGO A;  3QCG A;  5KA0 A;  1YTN A;  2CNH A;  1GFY A;  4IKC A;  1VHR A;  2H4K A;  1KAK A;  2HB1 A;  3D1O A;  4HRF A;  2F46 A;  1PTV A;  2CNE A;  1YPT A;  3V0J A;  4R30 A;  3QCK A;  5KA2 A;  2FJN A;  4QBW A;  2SHP A;  5LXQ B;  1NZ7 A;  1ECV A;  3QKP A;  1A5Y A;  3I7Z A;  1C83 A;  4KYQ A;  1EEN A;  3D1Q A;  2GWO A;  2PBN A;  4H1O A;  2B4S A;  2OZ5 A;  3BM8 A;  2G6Z A;  5KA9 A;  2QDP A;  4WU2 A;  4RH9 A;  1PTU A;  3MOZ A;  1ZC0 A;  3AWG A;  2ESB A;  4GS0 A;  1M3G A;  5K25 A;  5EHP A;  1YWF A;  3ZM0 A;  1ONZ A;  4QUN A;  4Z6B A;  1D5R A;  1XXP A;  4GE6 A;  1I9S A;  3O4U A;  3QCB A;  3MMJ A;  1C88 A;  2H02 A;  2ZMM A;  2QBQ A;  4DGX A;  2CJZ A;  1G4U S;  1OEM X;  3SME A;  4JMJ A;  3OLR A;  1YTW A;  1T4J A;  4TVV A;  3QCM A;  3QCC A;  2F6T A;  2F71 A;  1FPZ A;  2B4O A;  2QCT A;  5BUG A;  3ZMQ A;  1R6H A;  3S3E A;  4J51 A;  1GWZ A;  3ZM1 A;  1U25 A;  3CWE A;  1OEU A;  1YFO A;  5GTJ A;  1JF7 A;  3EU0 A;  3O4T A;  2QEP A;  4NND A;  2B07 A;  1I9T A;  2G59 A;  2BIJ A;  3I36 A;  4S0G A;  3V0I A;  4AZ1 A;  2HY3 A;  4NX8 A;  1XBO A;  1Q6M A;  4R0T A;  2CMA A;  1I57 A;  3QCD A;  3V0F A;  3EMU A;  5KAB A;  2VEV A;  3M4U A;  4HJP A;  2HC1 A;  4YAA A;  1P15 A;  3F9B A;  3SR9 A;  2B49 A;  2WGP A;  2Y96 A;  1YZ4 A;  4D3Q A;  4RI5 A;  5K9V A;  2A8B A;  2I6P A;  3RGQ A;  2J16 A;  3GXH A;  3MOW A;  3S4E A;  4ERC A;  1PTY A;  2I6I A;  3QKQ A;  4QAP A;  2QBR A;  3F81 A;  2CNG A;  1PA9 A;  1G4W R;  2BZL A;  4ZI4 A;  2NZ6 A;  2B4P A;  3F99 A;  4WOH A;  2BV5 A;  2F70 A;  2I4G A;  2PSZ A;  4GRZ A;  2B4U A;  5J8R A;  1ZCK A;  3ZM3 A;  3QCJ A;  2I4E A;  4QUM A;  1C86 A;  4OHD A;  1MKP A;  4NWF A;  1BZJ A;  4KYR A;  2C7S A;  1YN9 A;  3V0D A;  4DGP A;  2R0B A;  2BGE A;  3D9C A;  4OHH A;  4NWG A;  4PYH A;  4JBC A;  1X24 A;  4BPC A;  3A5J A;  2CMB A;  1OET A;  5K24 A;  2E0T A;  5KA1 A;  5IBS A;  3O4S A;  2AHS A;  1RPM A;  3ZM2 A;  3BLU A;  5K23 A;  2CMC A;  4GWF A;  3QCI A;  1G1G A;  2J16 B;  4PVG A;  2PA5 A;  1U24 A;  5KA7 A;  1JLN A;  2F6Y A;  1YGR A;  3U96 A;  5KAA A;  2HVL A;  1FPR A;  1Q6J A;  3LJ8 A;  2GP0 A;  1J4X A;  5I6V A;  1C87 A;  2CM8 A;  2NT7 A;  4KI9 A;  4R0S A;  3D44 A;  2Q47 A;  3S3H A;  1OHE A;  1Q6P A;  1RXD A;  2CFV A;  2H4V A;  4D3P A;  1PTT A;  1FQ1 A;  1WRM A;  4Y14 A;  2IMG A;  2CNI A;  4OHE A;  1G7G A;  2MBC A;  1Q6T A;  2HNQ A;  2ZN7 A;  2HCM A;  4WTY A;  1SUG A;  2NLK A;  4Y2E A;  2J17 A;  1KAV A;  5EHR A;  5KA8 A;  2I6J A;  1BZC A;  1G1H A;  2BGD A;  2A3K A;  2HC2 A;  3EZZ A;  4ZN5 A;  3V0E A;  2NV5 A;  4D3R A;  3S3F A;  2PI7 A;  2QDM A;  2I3U A;  4ZRT A;  3B7O A;  5BX1 A;  2F6W A;  2I42 A;  4OHI A;  2P6X A;  4JNB A;  5BZX A;  4B04 A;  3D1H A;  3F9A A;  1OHD A;  4MBB A;  1LAR A;  4GFV A;  4RH5 A;  1OES A;  1BZH A;  1C84 A;  1Q6N A;  4JMK A;  1OEV A;  1LQF A;  4GE5 A;  2CNF A;  2VEW A;  2OOQ A;  4GE2 A;  2PT0 A;  3CM3 A;  4GFU A;  1ZCL A;  5HDE A;  2PQ5 A;  4H34 A;  4QAH A;  2CM3 A;  1XM2 A;  1QZ0 A;  2H4G A;  3AWE A;  5K22 A;  1PA1 A;  1WCH A;  5K9W A;  2OUD A;  2CM2 A;  4RDD A;  2I6M A;  2FH7 A;  2GJT A;  2QCJ A;  2H03 A;  2HXP A;  1NWE A;  1OHC A;  5IBM A;  3EAX A;  4OHL A;  5M43 A;  3QCE A;  4ICZ A;  4I8N A;  3AWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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