1WCHA

Crystal structure of ptpl1 human tyrosine phosphatase mutated in colorectal cancer - evidence for a second phosphotyrosine substrate recognition pocket
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
308
structure length
308
Chain Sequence
HSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of Ptpl1/Fap-1 Human Tyrosine Phosphatase Mutated in Colorectal Cancer: Eveidence for a Second Phosphotyrosine Substrate Recognition Pocket
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13
total genus 102
structure length 308
sequence length 308
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1wchA00
4D3RA 4WOHA 3B7OA 2VEVA 1C83A 1Q6NA 3A5KA 2F6TA 2BZLA 3QCDA 2QEPA 3S4EA 2HCMA 1I9SA 4OHHA 3ZMPA 1D5RA 4Z6BA 2C7SA 5EHRA 2HXPA 2OC3A 3S3FA 1OHDA 3F81A 4QUMA 1OEVA 4WTYA 4ZI4A 2NT7A 1C86A 1YN9A 4TVVA 4NYHA 4ZRTA 4Y14A 3BLUA 1WCHA 3BLTA 1U25A 1YTNA 4ZN5A 2P6XA 2CNEA 3CWEA 2I6IA 1L8GA 4GS0A 1YGUA 4OHEA 3PS5A 3OMHA 1LQFA 2QBSA 3V0JA 1C85A 1OETA 1RXDA 4R0TA 5GTJA 4GRZA 2Y2FA 3GXHA 2QDPA 4JMJA 1NO6A 3O4TA 4MBBA 2FH7A 4HRFA 3MOZA 1PA9A 2C46A 1L8KA 2HY3A 4BJOA 1SUGA 3QCKA 1X24A 3AWEA 3AWFA 5BUGA 3QCBA 2BIJA 1J4XA 4H1OA 2CNIA 2CMAA 2H02A 2I3RA 4JBCA 4GFVA 4YAAA 2OZ5A 5KACA 2CMCA 1QXKA 5KA3A 3QCLA 5KA7A 4KYQA 1PTTA 3V0IA 5AWXA 5HDEA 4GE5A 2CM2A 2F71A 3LJ8A 2PBNA 2VEYA 4R30A 4RI5A 3V0DA 4HJPA 3O4UA 1YPTA 2AHSA 3QCJA 4D3QA 2NV5A 1G1HA 1OESA 2ZN7A 3QCEA 3O3LA 5KA4A 2BGEA 3RO1A 4JNBA 3ZM0A 1NWEA 1OEOX 4S0GA 4Y2EA 2HVLA 2VEXA 4HJQA 4GFUA 5BX1A 3SR9A 4AZ1A 2PT0A 1BZJA 1EEOA 2GJTA 1EENA 1NL9A 2F70A 4RHGA 1C88A 3I7ZA 3ZM2A 1ECVA 1T49A 5J8RA 1PTUA 1VHRA 3RZ2A 4H34A 3F9BA 2I4HA 2NZ6A 3ZM1A 3EU0A 2QBPA 1AAXA 2CNFA 5BZZA 1LARA 3QCMA 3N0AA 2PQ5A 2QCJA 3NMEA 2H04A 2CM3A 2FJNA 3U96A 4JMKA 1C87A 1MKPA 1PTVA 3V0FA 2Q05A 2F46A 4QUNA 5KADA 3I36A 1G7FA 1A5YA 4QAHA 1FPZA 2I6JA 4PVGA 3OLRA 2WGPA 1FQ1A 1NNYA 3ZMQA 1XM2A 2F6VA 2I75A 2OOQA 2NTAA 2PSZA 3D44A 2NT2A 4NWFA 1OEMX 1Q6TA 1WAXA 3ZV2A 2B07A 5KA0A 4J51A 3D1HA 2HNPA 1U24A 2Y96A 1G1FA 1BZHA 1PA1A 4OHIA 2CNGA 5K25A 1ONZA 2H03A 3RGOA 1JLNA 2QBQA 3QKQA 3QCIA 4GWFA 2A8BA 3S3EA 2B49A 1OHEA 5KA8A 3MMJA 5M43A 1RPMA 3MOWA 1YFOA 2I3UA 4WU3A 3F99A 3EMUA 2I5XA 1T4JA 5IBMA 2OUDA 4R0SA 3V0HA 3O4SA 2BV5A 1Q6SA 1XBOA 2E0TA 2CJZA 1R6HA 2B4PA 4RI4A 1OHCA 1YZ4A 2SHPA 4I8NA 3BRHA 3EZZA 4QBEA 4D3PA 2QDMA 2I4EA 2VEWA 2VEUA 1G4WR 1GWZA 1YWFA 2I4GA 2PA5A 1I9TA 3D42A 3RGQA 2QDCA 1U26A 2B4UA 3QKPA 2I6PA 5K9VA 1OEUA 1Q6MA 4RDDA 2HB1A 5EHPA 2RF6A 2J17A 4BPCA 2H4GA 2Q47A 5K24A 4NWGA 2ESBA 1QZ0A 2CM8A 4OHLA 1PYNA 1Q6JA 1G4US 1I57A 1ONYA 4RKKA 1ZC0A 4GRYA 5MMZB 3SMEA 4OHDA 1V3AA 2GP0A 1PH0A 4NNDA 2I1YA 4RH9A 3EAXA 1FPRA 2MBCA 4PYHA 2G59A 3GXGA 4RH5A 3QCCA 2J16B 2A3KA 1G1GA 2BGDA 4DGPA 4NX8A 4QBWA 2AZRA 3D1OA 2F6YA 3S3KA 2B3OA 2P4DA 4GE2A 1T48A 1XRIA 1ZCKA 4B04A 1KAVA 3QCFA 2HC1A 2I6OA 2G6ZA 2FJMA 2JJDA 3H2XA 2M3VA 3I80A 5KA2A 4KI9A 3QCGA 2YDUA 3V0EA 2H4VA 3F41A 3AWGA 4WU2A 5K23A 2CM7A 2CMBA 5K9WA 2F6WA 2GWOA 1JF7A 4KYRA 2F6FA 3A5JA 4ERCA 4YR8B 1PTYA 1Q6PA 1Q1MA 3M4UA 3CM3A 2CNHA 2R0BA 2I6MA 2I42A 2HNQA 3S4OA 1NZ7A 1G7GA 2DXPA 1P15A 5IBSA 4QAPA 4IKCA 3O5XA 3D1QA 3QCNA 2ZMMA 1ZCLA 4GE6A 1C84A 5KA1A 1M3GA 2H4KA 1WRMA 2IMGA 1KAKA 3D9CA 2NLKA 1YGRA 5BZXA 5K22A 1BZCA 3V0GA 3F9AA 1XXPA 1YTSA 2HC2A 4DGXA 2CFVA 5KAAA 2J16A 1GFYA 3QCHA 5KABA 1ZZWA 2QCTA 2QBRA 4ICZA 1XXVA 2F6ZA 3EB1A 3ZM3A 2B4OA 5I6VA 5LXQB 1LYVA 2PI7A 3S3HA 3BM8A 5KA9A 2B4SA 1PXHA 1NWLA 1YTWA
chains in the Genus database with same CATH superfamily
4D3RA 4WOHA 3B7OA 2VEVA 4ZIYA 1C83A 1Q6NA 3A5KA 2F6TA 2BZLA 3QCDA 2QEPA 3S4EA 1P31A 2HCMA 1I9SA 4OHHA 1GQYA 3ZMPA 2AM1A 1D5RA 4Z6BA 2C7SA 5EHRA 2HXPA 2OC3A 3S3FA 1OHDA 3F81A 4QUMA 1OEVA 4WTYA 4ZI4A 2NT7A 1C86A 1YN9A 4TVVA 2UUPA 3ZL8A 4NYHA 4ZRTA 4Y14A 3BLUA 1WCHA 2WTZA 3BLTA 1U25A 1YTNA 2JFHA 4ZN5A 2P6XA 2Y68A 3CWEA 2CNEA 2GCAA 1L8GA 2I6IA 4GS0A 1YGUA 4OHEA 3PS5A 3OMHA 1LQFA 2QBSA 3V0JA 1C85A 1OETA 1RXDA 4R0TA 5GTJA 4GRZA 2Y2FA 3GXHA 2QDPA 4JMJA 1NO6A 1P3DA 3O4TA 1GQQA 4MBBA 2FH7A 4HRFA 3MOZA 1PA9A 2C46A 1L8KA 2HY3A 4BJOA 1SUGA 2X5OA 3QCKA 1X24A 3AWEA 3AWFA 5BUGA 3QCBA 2BIJA 1J4XA 4H1OA 2CNIA 2CMAA 2H02A 2I3RA 4JBCA 4GFVA 4YAAA 2OZ5A 2VORA 5KACA 2CMCA 1QXKA 5KA3A 3QCLA 5KA7A 4KYQA 1PTTA 3V0IA 5AWXA 2UAGA 4HV4A 5HDEA 4GE5A 2CM2A 2F71A 3LJ8A 2PBNA 4CVMA 2VEYA 4R30A 4RI5A 3V0DA 4HJPA 3O4UA 1YPTA 2AHSA 3QCJA 4D3QA 2NV5A 1G1HA 1OESA 2ZN7A 3QCEA 3O3LA 5KA4A 2BGEA 3RO1A 4JNBA 2GC5A 3ZM0A 1NWEA 1OEOX 4S0GA 4Y2EA 3ZM5A 2HVLA 2VEXA 4HJQA 4GFUA 5BX1A 3SR9A 3UAGA 4AZ1A 2PT0A 1BZJA 1EEOA 2GJTA 2Y1OA 2VTDA 1EENA 1NL9A 2F70A 4CVKA 4RHGA 2AM2A 2JFGA 1C88A 3I7ZA 3ZM2A 1ECVA 1T49A 5J8RA 1PTUA 1VHRA 3RZ2A 4H34A 2Y67A 3F9BA 2I4HA 2NZ6A 3ZM1A 3EU0A 2GCBA 2QBPA 1AAXA 2CNFA 5BZZA 1LARA 3QCMA 3N0AA 2PQ5A 2QCJA 3NMEA 4C12A 2H04A 3MVNA 2CM3A 5A5EA 2FJNA 3U96A 3LK7A 4JMKA 1C87A 1MKPA 1PTVA 3V0FA 2Q05A 2F46A 4QUNA 5KADA 4C13A 3I36A 1G7FA 1A5YA 4QAHA 1FPZA 2I6JA 4PVGA 3OLRA 2WGPA 1FQ1A 1NNYA 3ZMQA 1XM2A 2XJAA 2F6VA 2I75A 2OOQA 1J6UA 2NTAA 2PSZA 2F00A 3D44A 2NT2A 2GC6A 4NWFA 1OEMX 1Q6TA 1WAXA 2Y66A 3ZV2A 3QCZA 2B07A 5KA0A 4J51A 3D1HA 2HNPA 1U24A 2Y96A 1G1FA 1BZHA 1PA1A 4OHIA 2CNGA 5K25A 1ONZA 2H03A 3RGOA 3PYZA 1JLNA 2QBQA 3QKQA 3QCIA 4GWFA 2A8BA 2JFFA 3S3EA 2B49A 1OHEA 5KA8A 3MMJA 5M43A 1RPMA 3MOWA 1YFOA 2I3UA 4WU3A 3F99A 3EMUA 2I5XA 2WJPA 1T4JA 5IBMA 2OUDA 4R0SA 1W78A 3V0HA 3O4SA 2BV5A 1Q6SA 4BUCA 1XBOA 2E0TA 2CJZA 4UAGA 1R6HA 2B4PA 2UUOA 4RI4A 1OHCA 1YZ4A 2SHPA 4I8NA 3HN7A 3BRHA 3EZZA 4QBEA 4D3PA 2XPCA 2QDMA 2I4EA 2VEWA 2VEUA 1G4WR 1GWZA 1YWFA 2I4GA 2PA5A 1I9TA 3D42A 3RGQA 2QDCA 1U26A 2B4UA 3QKPA 2I6PA 3ZM6A 5K9VA 1OEUA 1Q6MA 4RDDA 2HB1A 5EHPA 2RF6A 2J17A 4BPCA 2H4GA 2Q47A 3N2AA 5K24A 2VTEA 4NWGA 4QDIA 2ESBA 1QZ0A 2CM8A 4OHLA 1PYNA 1Q6JA 1G4US 1I57A 1ONYA 4RKKA 1ZC0A 4GRYA 5MMZB 3SMEA 4OHDA 1V3AA 2GP0A 1PH0A 4NNDA 2I1YA 4RH9A 3EAXA 1FPRA 2MBCA 4PYHA 2G59A 3GXGA 4RH5A 3QCCA 2J16B 2A3KA 1G1GA 2BGDA 4DGPA 4NX8A 4QBWA 2AZRA 3D1OA 2F6YA 3S3KA 2B3OA 2P4DA 4GE2A 1T48A 1XRIA 1ZCKA 4B04A 1KAVA 1JBVA 3QCFA 2HC1A 2I6OA 2G6ZA 2FJMA 2JJDA 3H2XA 2M3VA 3I80A 5KA2A 4KI9A 3QCGA 2YDUA 3V0EA 2H4VA 3F41A 3AWGA 1EEHA 4WU2A 5K23A 2CM7A 2CMBA 5A5FA 2VOSA 1FGSA 5K9WA 2F6WA 2GWOA 1JF7A 4KYRA 2F6FA 3A5JA 4ERCA 4YR8B 1PTYA 1Q6PA 1Q1MA 3M4UA 3CM3A 2CNHA 2R0BA 2I6MA 2I42A 2HNQA 3S4OA 1NZ7A 1G7GA 2DXPA 1P15A 5IBSA 4QAPA 1O5ZA 4IKCA 1GG4A 3D1QA 3O5XA 3QCNA 4QF5A 2ZMMA 1ZCLA 4GE6A 1C84A 5KA1A 1M3GA 2H4KA 1JBWA 1WRMA 2IMGA 1KAKA 3D9CA 2NLKA 1E8CA 1YGRA 5BZXA 5K22A 1BZCA 3V0GA 1E0DA 3F9AA 1XXPA 1YTSA 2HC2A 4DGXA 2CFVA 5KAAA 2J16A 4BUBA 1GFYA 3QCHA 5KABA 1ZZWA 2QCTA 2QBRA 4ICZA 3NRSA 1XXVA 2F6ZA 3EB1A 3ZM3A 2B4OA 5I6VA 5LXQB 1LYVA 2PI7A 3S3HA 4CVLA 1UAGA 3BM8A 5KA9A 2B4SA 1PXHA 1NWLA 1YTWA 1W7KA
chains in the Genus database with same CATH topology
4D3RA 4WOHA 3B7OA 2VEVA 1C83A 1Q6NA 3A5KA 2F6TA 2BZLA 3QCDA 2QEPA 3S4EA 2HCMA 1I9SA 4OHHA 3ZMPA 1D5RA 4Z6BA 2C7SA 5EHRA 2HXPA 2OC3A 3S3FA 1OHDA 3F81A 4QUMA 1OEVA 4WTYA 4ZI4A 2NT7A 1C86A 1YN9A 4TVVA 4NYHA 4ZRTA 4Y14A 3BLUA 1WCHA 3BLTA 1U25A 1YTNA 4ZN5A 2P6XA 2CNEA 3CWEA 2I6IA 1L8GA 4GS0A 1YGUA 4OHEA 3PS5A 3OMHA 1LQFA 2QBSA 3V0JA 1C85A 1OETA 1RXDA 4R0TA 5GTJA 4GRZA 2Y2FA 3GXHA 2QDPA 4JMJA 1NO6A 3O4TA 4MBBA 2FH7A 4HRFA 3MOZA 1PA9A 2C46A 1L8KA 2HY3A 4BJOA 1SUGA 3QCKA 1X24A 3AWEA 3AWFA 5BUGA 3QCBA 2BIJA 1J4XA 4H1OA 2CNIA 2CMAA 2H02A 2I3RA 4JBCA 4GFVA 4YAAA 2OZ5A 5KACA 2CMCA 1QXKA 5KA3A 3QCLA 5KA7A 4KYQA 1PTTA 3V0IA 5AWXA 5HDEA 4GE5A 2CM2A 2F71A 3LJ8A 2PBNA 2VEYA 4R30A 4RI5A 3V0DA 4HJPA 3O4UA 1YPTA 2AHSA 3QCJA 4D3QA 2NV5A 1G1HA 1OESA 2ZN7A 3QCEA 3O3LA 5KA4A 2BGEA 3RO1A 4JNBA 3ZM0A 1NWEA 1OEOX 4S0GA 4Y2EA 2HVLA 2VEXA 4HJQA 4GFUA 5BX1A 3SR9A 4AZ1A 2PT0A 1BZJA 1EEOA 2GJTA 1EENA 1NL9A 2F70A 4RHGA 1C88A 3I7ZA 3ZM2A 1ECVA 1T49A 5J8RA 1PTUA 1VHRA 3RZ2A 4H34A 3F9BA 2I4HA 2NZ6A 3ZM1A 3EU0A 2QBPA 1AAXA 2CNFA 5BZZA 1LARA 3QCMA 3N0AA 2PQ5A 2QCJA 3NMEA 2H04A 2CM3A 2FJNA 3U96A 4JMKA 1C87A 1MKPA 1PTVA 3V0FA 2Q05A 2F46A 4QUNA 5KADA 3I36A 1G7FA 1A5YA 4QAHA 1FPZA 2I6JA 4PVGA 3OLRA 2WGPA 1FQ1A 1NNYA 3ZMQA 1XM2A 2F6VA 2I75A 2OOQA 2NTAA 2PSZA 3D44A 2NT2A 4NWFA 1OEMX 1Q6TA 1WAXA 3ZV2A 2B07A 5KA0A 4J51A 3D1HA 2HNPA 1U24A 2Y96A 1G1FA 1BZHA 1PA1A 4OHIA 2CNGA 5K25A 1ONZA 2H03A 3RGOA 1JLNA 2QBQA 3QKQA 3QCIA 4GWFA 2A8BA 3S3EA 2B49A 1OHEA 5KA8A 3MMJA 5M43A 1RPMA 3MOWA 1YFOA 2I3UA 4WU3A 3F99A 3EMUA 2I5XA 1T4JA 5IBMA 2OUDA 4R0SA 3V0HA 3O4SA 2BV5A 1Q6SA 1XBOA 2E0TA 2CJZA 1R6HA 2B4PA 4RI4A 1OHCA 1YZ4A 2SHPA 4I8NA 3BRHA 3EZZA 4QBEA 4D3PA 2QDMA 2I4EA 2VEWA 2VEUA 1G4WR 1GWZA 1YWFA 2I4GA 2PA5A 1I9TA 3D42A 3RGQA 2QDCA 1U26A 2B4UA 3QKPA 2I6PA 5K9VA 1OEUA 1Q6MA 4RDDA 2HB1A 5EHPA 2RF6A 2J17A 4BPCA 2H4GA 2Q47A 5K24A 4NWGA 2ESBA 1QZ0A 2CM8A 4OHLA 1PYNA 1Q6JA 1G4US 1I57A 1ONYA 4RKKA 1ZC0A 4GRYA 5MMZB 3SMEA 4OHDA 1V3AA 2GP0A 1PH0A 4NNDA 2I1YA 4RH9A 3EAXA 1FPRA 2MBCA 4PYHA 2G59A 3GXGA 4RH5A 3QCCA 2J16B 2A3KA 1G1GA 2BGDA 4DGPA 4NX8A 4QBWA 2AZRA 3D1OA 2F6YA 3S3KA 2B3OA 2P4DA 4GE2A 1T48A 1XRIA 1ZCKA 4B04A 1KAVA 3QCFA 2HC1A 2I6OA 2G6ZA 2FJMA 2JJDA 3H2XA 2M3VA 3I80A 5KA2A 4KI9A 3QCGA 2YDUA 3V0EA 2H4VA 3F41A 3AWGA 4WU2A 5K23A 2CM7A 2CMBA 5K9WA 2F6WA 2GWOA 1JF7A 4KYRA 2F6FA 3A5JA 4ERCA 4YR8B 1PTYA 1Q6PA 1Q1MA 3M4UA 3CM3A 2CNHA 2R0BA 2I6MA 2I42A 2HNQA 3S4OA 1NZ7A 1G7GA 2DXPA 1P15A 5IBSA 4QAPA 4IKCA 3O5XA 3D1QA 3QCNA 2ZMMA 1ZCLA 4GE6A 1C84A 5KA1A 1M3GA 2H4KA 1WRMA 2IMGA 1KAKA 3D9CA 2NLKA 1YGRA 5BZXA 5K22A 1BZCA 3V0GA 3F9AA 1XXPA 1YTSA 2HC2A 4DGXA 2CFVA 5KAAA 2J16A 1GFYA 3QCHA 5KABA 1ZZWA 2QCTA 2QBRA 4ICZA 1XXVA 2F6ZA 3EB1A 3ZM3A 2B4OA 5I6VA 5LXQB 1LYVA 2PI7A 3S3HA 3BM8A 5KA9A 2B4SA 1PXHA 1NWLA 1YTWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D3R A;  4WOH A;  3B7O A;  2VEV A;  1C83 A;  1Q6N A;  3A5K A;  2F6T A;  2BZL A;  3QCD A;  2QEP A;  3S4E A;  2HCM A;  1I9S A;  4OHH A;  3ZMP A;  1D5R A;  4Z6B A;  2C7S A;  5EHR A;  2HXP A;  2OC3 A;  3S3F A;  1OHD A;  3F81 A;  4QUM A;  1OEV A;  4WTY A;  4ZI4 A;  2NT7 A;  1C86 A;  1YN9 A;  4TVV A;  4NYH A;  4ZRT A;  4Y14 A;  3BLU A;  1WCH A;  3BLT A;  1U25 A;  1YTN A;  4ZN5 A;  2P6X A;  2CNE A;  3CWE A;  2I6I A;  1L8G A;  4GS0 A;  1YGU A;  4OHE A;  3PS5 A;  3OMH A;  1LQF A;  2QBS A;  3V0J A;  1C85 A;  1OET A;  1RXD A;  4R0T A;  5GTJ A;  4GRZ A;  2Y2F A;  3GXH A;  2QDP A;  4JMJ A;  1NO6 A;  3O4T A;  4MBB A;  2FH7 A;  4HRF A;  3MOZ A;  1PA9 A;  2C46 A;  1L8K A;  2HY3 A;  4BJO A;  1SUG A;  3QCK A;  1X24 A;  3AWE A;  3AWF A;  5BUG A;  3QCB A;  2BIJ A;  1J4X A;  4H1O A;  2CNI A;  2CMA A;  2H02 A;  2I3R A;  4JBC A;  4GFV A;  4YAA A;  2OZ5 A;  5KAC A;  2CMC A;  1QXK A;  5KA3 A;  3QCL A;  5KA7 A;  4KYQ A;  1PTT A;  3V0I A;  5AWX A;  5HDE A;  4GE5 A;  2CM2 A;  2F71 A;  3LJ8 A;  2PBN A;  2VEY A;  4R30 A;  4RI5 A;  3V0D A;  4HJP A;  3O4U A;  1YPT A;  2AHS A;  3QCJ A;  4D3Q A;  2NV5 A;  1G1H A;  1OES A;  2ZN7 A;  3QCE A;  3O3L A;  5KA4 A;  2BGE A;  3RO1 A;  4JNB A;  3ZM0 A;  1NWE A;  1OEO X;  4S0G A;  4Y2E A;  2HVL A;  2VEX A;  4HJQ A;  4GFU A;  5BX1 A;  3SR9 A;  4AZ1 A;  2PT0 A;  1BZJ A;  1EEO A;  2GJT A;  1EEN A;  1NL9 A;  2F70 A;  4RHG A;  1C88 A;  3I7Z A;  3ZM2 A;  1ECV A;  1T49 A;  5J8R A;  1PTU A;  1VHR A;  3RZ2 A;  4H34 A;  3F9B A;  2I4H A;  2NZ6 A;  3ZM1 A;  3EU0 A;  2QBP A;  1AAX A;  2CNF A;  5BZZ A;  1LAR A;  3QCM A;  3N0A A;  2PQ5 A;  2QCJ A;  3NME A;  2H04 A;  2CM3 A;  2FJN A;  3U96 A;  4JMK A;  1C87 A;  1MKP A;  1PTV A;  3V0F A;  2Q05 A;  2F46 A;  4QUN A;  5KAD A;  3I36 A;  1G7F A;  1A5Y A;  4QAH A;  1FPZ A;  2I6J A;  4PVG A;  3OLR A;  2WGP A;  1FQ1 A;  1NNY A;  3ZMQ A;  1XM2 A;  2F6V A;  2I75 A;  2OOQ A;  2NTA A;  2PSZ A;  3D44 A;  2NT2 A;  4NWF A;  1OEM X;  1Q6T A;  1WAX A;  3ZV2 A;  2B07 A;  5KA0 A;  4J51 A;  3D1H A;  2HNP A;  1U24 A;  2Y96 A;  1G1F A;  1BZH A;  1PA1 A;  4OHI A;  2CNG A;  5K25 A;  1ONZ A;  2H03 A;  3RGO A;  1JLN A;  2QBQ A;  3QKQ A;  3QCI A;  4GWF A;  2A8B A;  3S3E A;  2B49 A;  1OHE A;  5KA8 A;  3MMJ A;  5M43 A;  1RPM A;  3MOW A;  1YFO A;  2I3U A;  4WU3 A;  3F99 A;  3EMU A;  2I5X A;  1T4J A;  5IBM A;  2OUD A;  4R0S A;  3V0H A;  3O4S A;  2BV5 A;  1Q6S A;  1XBO A;  2E0T A;  2CJZ A;  1R6H A;  2B4P A;  4RI4 A;  1OHC A;  1YZ4 A;  2SHP A;  4I8N A;  3BRH A;  3EZZ A;  4QBE A;  4D3P A;  2QDM A;  2I4E A;  2VEW A;  2VEU A;  1G4W R;  1GWZ A;  1YWF A;  2I4G A;  2PA5 A;  1I9T A;  3D42 A;  3RGQ A;  2QDC A;  1U26 A;  2B4U A;  3QKP A;  2I6P A;  5K9V A;  1OEU A;  1Q6M A;  4RDD A;  2HB1 A;  5EHP A;  2RF6 A;  2J17 A;  4BPC A;  2H4G A;  2Q47 A;  5K24 A;  4NWG A;  2ESB A;  1QZ0 A;  2CM8 A;  4OHL A;  1PYN A;  1Q6J A;  1G4U S;  1I57 A;  1ONY A;  4RKK A;  1ZC0 A;  4GRY A;  5MMZ B;  3SME A;  4OHD A;  1V3A A;  2GP0 A;  1PH0 A;  4NND A;  2I1Y A;  4RH9 A;  3EAX A;  1FPR A;  2MBC A;  4PYH A;  2G59 A;  3GXG A;  4RH5 A;  3QCC A;  2J16 B;  2A3K A;  1G1G A;  2BGD A;  4DGP A;  4NX8 A;  4QBW A;  2AZR A;  3D1O A;  2F6Y A;  3S3K A;  2B3O A;  2P4D A;  4GE2 A;  1T48 A;  1XRI A;  1ZCK A;  4B04 A;  1KAV A;  3QCF A;  2HC1 A;  2I6O A;  2G6Z A;  2FJM A;  2JJD A;  3H2X A;  2M3V A;  3I80 A;  5KA2 A;  4KI9 A;  3QCG A;  2YDU A;  3V0E A;  2H4V A;  3F41 A;  3AWG A;  4WU2 A;  5K23 A;  2CM7 A;  2CMB A;  5K9W A;  2F6W A;  2GWO A;  1JF7 A;  4KYR A;  2F6F A;  3A5J A;  4ERC A;  4YR8 B;  1PTY A;  1Q6P A;  1Q1M A;  3M4U A;  3CM3 A;  2CNH A;  2R0B A;  2I6M A;  2I42 A;  2HNQ A;  3S4O A;  1NZ7 A;  1G7G A;  2DXP A;  1P15 A;  5IBS A;  4QAP A;  4IKC A;  3O5X A;  3D1Q A;  3QCN A;  2ZMM A;  1ZCL A;  4GE6 A;  1C84 A;  5KA1 A;  1M3G A;  2H4K A;  1WRM A;  2IMG A;  1KAK A;  3D9C A;  2NLK A;  1YGR A;  5BZX A;  5K22 A;  1BZC A;  3V0G A;  3F9A A;  1XXP A;  1YTS A;  2HC2 A;  4DGX A;  2CFV A;  5KAA A;  2J16 A;  1GFY A;  3QCH A;  5KAB A;  1ZZW A;  2QCT A;  2QBR A;  4ICZ A;  1XXV A;  2F6Z A;  3EB1 A;  3ZM3 A;  2B4O A;  5I6V A;  5LXQ B;  1LYV A;  2PI7 A;  3S3H A;  3BM8 A;  5KA9 A;  2B4S A;  1PXH A;  1NWL A;  1YTW A; 
#chains in the Genus database with same CATH topology
 4D3R A;  4WOH A;  3B7O A;  2VEV A;  4ZIY A;  1C83 A;  1Q6N A;  3A5K A;  2F6T A;  2BZL A;  3QCD A;  2QEP A;  3S4E A;  1P31 A;  2HCM A;  1I9S A;  4OHH A;  1GQY A;  3ZMP A;  2AM1 A;  1D5R A;  4Z6B A;  2C7S A;  5EHR A;  2HXP A;  2OC3 A;  3S3F A;  1OHD A;  3F81 A;  4QUM A;  1OEV A;  4WTY A;  4ZI4 A;  2NT7 A;  1C86 A;  1YN9 A;  4TVV A;  2UUP A;  3ZL8 A;  4NYH A;  4ZRT A;  4Y14 A;  3BLU A;  1WCH A;  2WTZ A;  3BLT A;  1U25 A;  1YTN A;  2JFH A;  4ZN5 A;  2P6X A;  2Y68 A;  3CWE A;  2CNE A;  2GCA A;  1L8G A;  2I6I A;  4GS0 A;  1YGU A;  4OHE A;  3PS5 A;  3OMH A;  1LQF A;  2QBS A;  3V0J A;  1C85 A;  1OET A;  1RXD A;  4R0T A;  5GTJ A;  4GRZ A;  2Y2F A;  3GXH A;  2QDP A;  4JMJ A;  1NO6 A;  1P3D A;  3O4T A;  1GQQ A;  4MBB A;  2FH7 A;  4HRF A;  3MOZ A;  1PA9 A;  2C46 A;  1L8K A;  2HY3 A;  4BJO A;  1SUG A;  2X5O A;  3QCK A;  1X24 A;  3AWE A;  3AWF A;  5BUG A;  3QCB A;  2BIJ A;  1J4X A;  4H1O A;  2CNI A;  2CMA A;  2H02 A;  2I3R A;  4JBC A;  4GFV A;  4YAA A;  2OZ5 A;  2VOR A;  5KAC A;  2CMC A;  1QXK A;  5KA3 A;  3QCL A;  5KA7 A;  4KYQ A;  1PTT A;  3V0I A;  5AWX A;  2UAG A;  4HV4 A;  5HDE A;  4GE5 A;  2CM2 A;  2F71 A;  3LJ8 A;  2PBN A;  4CVM A;  2VEY A;  4R30 A;  4RI5 A;  3V0D A;  4HJP A;  3O4U A;  1YPT A;  2AHS A;  3QCJ A;  4D3Q A;  2NV5 A;  1G1H A;  1OES A;  2ZN7 A;  3QCE A;  3O3L A;  5KA4 A;  2BGE A;  3RO1 A;  4JNB A;  2GC5 A;  3ZM0 A;  1NWE A;  1OEO X;  4S0G A;  4Y2E A;  3ZM5 A;  2HVL A;  2VEX A;  4HJQ A;  4GFU A;  5BX1 A;  3SR9 A;  3UAG A;  4AZ1 A;  2PT0 A;  1BZJ A;  1EEO A;  2GJT A;  2Y1O A;  2VTD A;  1EEN A;  1NL9 A;  2F70 A;  4CVK A;  4RHG A;  2AM2 A;  2JFG A;  1C88 A;  3I7Z A;  3ZM2 A;  1ECV A;  1T49 A;  5J8R A;  1PTU A;  1VHR A;  3RZ2 A;  4H34 A;  2Y67 A;  3F9B A;  2I4H A;  2NZ6 A;  3ZM1 A;  3EU0 A;  2GCB A;  2QBP A;  1AAX A;  2CNF A;  5BZZ A;  1LAR A;  3QCM A;  3N0A A;  2PQ5 A;  2QCJ A;  3NME A;  4C12 A;  2H04 A;  3MVN A;  2CM3 A;  5A5E A;  2FJN A;  3U96 A;  3LK7 A;  4JMK A;  1C87 A;  1MKP A;  1PTV A;  3V0F A;  2Q05 A;  2F46 A;  4QUN A;  5KAD A;  4C13 A;  3I36 A;  1G7F A;  1A5Y A;  4QAH A;  1FPZ A;  2I6J A;  4PVG A;  3OLR A;  2WGP A;  1FQ1 A;  1NNY A;  3ZMQ A;  1XM2 A;  2XJA A;  2F6V A;  2I75 A;  2OOQ A;  1J6U A;  2NTA A;  2PSZ A;  2F00 A;  3D44 A;  2NT2 A;  2GC6 A;  4NWF A;  1OEM X;  1Q6T A;  1WAX A;  2Y66 A;  3ZV2 A;  3QCZ A;  2B07 A;  5KA0 A;  4J51 A;  3D1H A;  2HNP A;  1U24 A;  2Y96 A;  1G1F A;  1BZH A;  1PA1 A;  4OHI A;  2CNG A;  5K25 A;  1ONZ A;  2H03 A;  3RGO A;  3PYZ A;  1JLN A;  2QBQ A;  3QKQ A;  3QCI A;  4GWF A;  2A8B A;  2JFF A;  3S3E A;  2B49 A;  1OHE A;  5KA8 A;  3MMJ A;  5M43 A;  1RPM A;  3MOW A;  1YFO A;  2I3U A;  4WU3 A;  3F99 A;  3EMU A;  2I5X A;  2WJP A;  1T4J A;  5IBM A;  2OUD A;  4R0S A;  1W78 A;  3V0H A;  3O4S A;  2BV5 A;  1Q6S A;  4BUC A;  1XBO A;  2E0T A;  2CJZ A;  4UAG A;  1R6H A;  2B4P A;  2UUO A;  4RI4 A;  1OHC A;  1YZ4 A;  2SHP A;  4I8N A;  3HN7 A;  3BRH A;  3EZZ A;  4QBE A;  4D3P A;  2XPC A;  2QDM A;  2I4E A;  2VEW A;  2VEU A;  1G4W R;  1GWZ A;  1YWF A;  2I4G A;  2PA5 A;  1I9T A;  3D42 A;  3RGQ A;  2QDC A;  1U26 A;  2B4U A;  3QKP A;  2I6P A;  3ZM6 A;  5K9V A;  1OEU A;  1Q6M A;  4RDD A;  2HB1 A;  5EHP A;  2RF6 A;  2J17 A;  4BPC A;  2H4G A;  2Q47 A;  3N2A A;  5K24 A;  2VTE A;  4NWG A;  4QDI A;  2ESB A;  1QZ0 A;  2CM8 A;  4OHL A;  1PYN A;  1Q6J A;  1G4U S;  1I57 A;  1ONY A;  4RKK A;  1ZC0 A;  4GRY A;  5MMZ B;  3SME A;  4OHD A;  1V3A A;  2GP0 A;  1PH0 A;  4NND A;  2I1Y A;  4RH9 A;  3EAX A;  1FPR A;  2MBC A;  4PYH A;  2G59 A;  3GXG A;  4RH5 A;  3QCC A;  2J16 B;  2A3K A;  1G1G A;  2BGD A;  4DGP A;  4NX8 A;  4QBW A;  2AZR A;  3D1O A;  2F6Y A;  3S3K A;  2B3O A;  2P4D A;  4GE2 A;  1T48 A;  1XRI A;  1ZCK A;  4B04 A;  1KAV A;  1JBV A;  3QCF A;  2HC1 A;  2I6O A;  2G6Z A;  2FJM A;  2JJD A;  3H2X A;  2M3V A;  3I80 A;  5KA2 A;  4KI9 A;  3QCG A;  2YDU A;  3V0E A;  2H4V A;  3F41 A;  3AWG A;  1EEH A;  4WU2 A;  5K23 A;  2CM7 A;  2CMB A;  5A5F A;  2VOS A;  1FGS A;  5K9W A;  2F6W A;  2GWO A;  1JF7 A;  4KYR A;  2F6F A;  3A5J A;  4ERC A;  4YR8 B;  1PTY A;  1Q6P A;  1Q1M A;  3M4U A;  3CM3 A;  2CNH A;  2R0B A;  2I6M A;  2I42 A;  2HNQ A;  3S4O A;  1NZ7 A;  1G7G A;  2DXP A;  1P15 A;  5IBS A;  4QAP A;  1O5Z A;  4IKC A;  1GG4 A;  3D1Q A;  3O5X A;  3QCN A;  4QF5 A;  2ZMM A;  1ZCL A;  4GE6 A;  1C84 A;  5KA1 A;  1M3G A;  2H4K A;  1JBW A;  1WRM A;  2IMG A;  1KAK A;  3D9C A;  2NLK A;  1E8C A;  1YGR A;  5BZX A;  5K22 A;  1BZC A;  3V0G A;  1E0D A;  3F9A A;  1XXP A;  1YTS A;  2HC2 A;  4DGX A;  2CFV A;  5KAA A;  2J16 A;  4BUB A;  1GFY A;  3QCH A;  5KAB A;  1ZZW A;  2QCT A;  2QBR A;  4ICZ A;  3NRS A;  1XXV A;  2F6Z A;  3EB1 A;  3ZM3 A;  2B4O A;  5I6V A;  5LXQ B;  1LYV A;  2PI7 A;  3S3H A;  4CVL A;  1UAG A;  3BM8 A;  5KA9 A;  2B4S A;  1PXH A;  1NWL A;  1YTW A;  1W7K A; 
#chains in the Genus database with same CATH homology
 4D3R A;  4WOH A;  3B7O A;  2VEV A;  1C83 A;  1Q6N A;  3A5K A;  2F6T A;  2BZL A;  3QCD A;  2QEP A;  3S4E A;  2HCM A;  1I9S A;  4OHH A;  3ZMP A;  1D5R A;  4Z6B A;  2C7S A;  5EHR A;  2HXP A;  2OC3 A;  3S3F A;  1OHD A;  3F81 A;  4QUM A;  1OEV A;  4WTY A;  4ZI4 A;  2NT7 A;  1C86 A;  1YN9 A;  4TVV A;  4NYH A;  4ZRT A;  4Y14 A;  3BLU A;  1WCH A;  3BLT A;  1U25 A;  1YTN A;  4ZN5 A;  2P6X A;  2CNE A;  3CWE A;  2I6I A;  1L8G A;  4GS0 A;  1YGU A;  4OHE A;  3PS5 A;  3OMH A;  1LQF A;  2QBS A;  3V0J A;  1C85 A;  1OET A;  1RXD A;  4R0T A;  5GTJ A;  4GRZ A;  2Y2F A;  3GXH A;  2QDP A;  4JMJ A;  1NO6 A;  3O4T A;  4MBB A;  2FH7 A;  4HRF A;  3MOZ A;  1PA9 A;  2C46 A;  1L8K A;  2HY3 A;  4BJO A;  1SUG A;  3QCK A;  1X24 A;  3AWE A;  3AWF A;  5BUG A;  3QCB A;  2BIJ A;  1J4X A;  4H1O A;  2CNI A;  2CMA A;  2H02 A;  2I3R A;  4JBC A;  4GFV A;  4YAA A;  2OZ5 A;  5KAC A;  2CMC A;  1QXK A;  5KA3 A;  3QCL A;  5KA7 A;  4KYQ A;  1PTT A;  3V0I A;  5AWX A;  5HDE A;  4GE5 A;  2CM2 A;  2F71 A;  3LJ8 A;  2PBN A;  2VEY A;  4R30 A;  4RI5 A;  3V0D A;  4HJP A;  3O4U A;  1YPT A;  2AHS A;  3QCJ A;  4D3Q A;  2NV5 A;  1G1H A;  1OES A;  2ZN7 A;  3QCE A;  3O3L A;  5KA4 A;  2BGE A;  3RO1 A;  4JNB A;  3ZM0 A;  1NWE A;  1OEO X;  4S0G A;  4Y2E A;  2HVL A;  2VEX A;  4HJQ A;  4GFU A;  5BX1 A;  3SR9 A;  4AZ1 A;  2PT0 A;  1BZJ A;  1EEO A;  2GJT A;  1EEN A;  1NL9 A;  2F70 A;  4RHG A;  1C88 A;  3I7Z A;  3ZM2 A;  1ECV A;  1T49 A;  5J8R A;  1PTU A;  1VHR A;  3RZ2 A;  4H34 A;  3F9B A;  2I4H A;  2NZ6 A;  3ZM1 A;  3EU0 A;  2QBP A;  1AAX A;  2CNF A;  5BZZ A;  1LAR A;  3QCM A;  3N0A A;  2PQ5 A;  2QCJ A;  3NME A;  2H04 A;  2CM3 A;  2FJN A;  3U96 A;  4JMK A;  1C87 A;  1MKP A;  1PTV A;  3V0F A;  2Q05 A;  2F46 A;  4QUN A;  5KAD A;  3I36 A;  1G7F A;  1A5Y A;  4QAH A;  1FPZ A;  2I6J A;  4PVG A;  3OLR A;  2WGP A;  1FQ1 A;  1NNY A;  3ZMQ A;  1XM2 A;  2F6V A;  2I75 A;  2OOQ A;  2NTA A;  2PSZ A;  3D44 A;  2NT2 A;  4NWF A;  1OEM X;  1Q6T A;  1WAX A;  3ZV2 A;  2B07 A;  5KA0 A;  4J51 A;  3D1H A;  2HNP A;  1U24 A;  2Y96 A;  1G1F A;  1BZH A;  1PA1 A;  4OHI A;  2CNG A;  5K25 A;  1ONZ A;  2H03 A;  3RGO A;  1JLN A;  2QBQ A;  3QKQ A;  3QCI A;  4GWF A;  2A8B A;  3S3E A;  2B49 A;  1OHE A;  5KA8 A;  3MMJ A;  5M43 A;  1RPM A;  3MOW A;  1YFO A;  2I3U A;  4WU3 A;  3F99 A;  3EMU A;  2I5X A;  1T4J A;  5IBM A;  2OUD A;  4R0S A;  3V0H A;  3O4S A;  2BV5 A;  1Q6S A;  1XBO A;  2E0T A;  2CJZ A;  1R6H A;  2B4P A;  4RI4 A;  1OHC A;  1YZ4 A;  2SHP A;  4I8N A;  3BRH A;  3EZZ A;  4QBE A;  4D3P A;  2QDM A;  2I4E A;  2VEW A;  2VEU A;  1G4W R;  1GWZ A;  1YWF A;  2I4G A;  2PA5 A;  1I9T A;  3D42 A;  3RGQ A;  2QDC A;  1U26 A;  2B4U A;  3QKP A;  2I6P A;  5K9V A;  1OEU A;  1Q6M A;  4RDD A;  2HB1 A;  5EHP A;  2RF6 A;  2J17 A;  4BPC A;  2H4G A;  2Q47 A;  5K24 A;  4NWG A;  2ESB A;  1QZ0 A;  2CM8 A;  4OHL A;  1PYN A;  1Q6J A;  1G4U S;  1I57 A;  1ONY A;  4RKK A;  1ZC0 A;  4GRY A;  5MMZ B;  3SME A;  4OHD A;  1V3A A;  2GP0 A;  1PH0 A;  4NND A;  2I1Y A;  4RH9 A;  3EAX A;  1FPR A;  2MBC A;  4PYH A;  2G59 A;  3GXG A;  4RH5 A;  3QCC A;  2J16 B;  2A3K A;  1G1G A;  2BGD A;  4DGP A;  4NX8 A;  4QBW A;  2AZR A;  3D1O A;  2F6Y A;  3S3K A;  2B3O A;  2P4D A;  4GE2 A;  1T48 A;  1XRI A;  1ZCK A;  4B04 A;  1KAV A;  3QCF A;  2HC1 A;  2I6O A;  2G6Z A;  2FJM A;  2JJD A;  3H2X A;  2M3V A;  3I80 A;  5KA2 A;  4KI9 A;  3QCG A;  2YDU A;  3V0E A;  2H4V A;  3F41 A;  3AWG A;  4WU2 A;  5K23 A;  2CM7 A;  2CMB A;  5K9W A;  2F6W A;  2GWO A;  1JF7 A;  4KYR A;  2F6F A;  3A5J A;  4ERC A;  4YR8 B;  1PTY A;  1Q6P A;  1Q1M A;  3M4U A;  3CM3 A;  2CNH A;  2R0B A;  2I6M A;  2I42 A;  2HNQ A;  3S4O A;  1NZ7 A;  1G7G A;  2DXP A;  1P15 A;  5IBS A;  4QAP A;  4IKC A;  3O5X A;  3D1Q A;  3QCN A;  2ZMM A;  1ZCL A;  4GE6 A;  1C84 A;  5KA1 A;  1M3G A;  2H4K A;  1WRM A;  2IMG A;  1KAK A;  3D9C A;  2NLK A;  1YGR A;  5BZX A;  5K22 A;  1BZC A;  3V0G A;  3F9A A;  1XXP A;  1YTS A;  2HC2 A;  4DGX A;  2CFV A;  5KAA A;  2J16 A;  1GFY A;  3QCH A;  5KAB A;  1ZZW A;  2QCT A;  2QBR A;  4ICZ A;  1XXV A;  2F6Z A;  3EB1 A;  3ZM3 A;  2B4O A;  5I6V A;  5LXQ B;  1LYV A;  2PI7 A;  3S3H A;  3BM8 A;  5KA9 A;  2B4S A;  1PXH A;  1NWL A;  1YTW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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