2BGEA

Structure-based design of protein tyrosine phosphatase-1b inhibitors
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
297
structure length
297
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 108
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2bgeA00
4HJPA 4OHIA 1YTNA 3S3EA 2CMBA 5IBSA 3PS5A 1I9TA 1BZJA 1MKPA 2A8BA 1Q6PA 2HCMA 2A3KA 4GFUA 3V0HA 2FJMA 2CFVA 2CNIA 3BLTA 3O3LA 5K24A 1NO6A 2F6ZA 4GFVA 1QZ0A 2F71A 2CMAA 1C84A 2I75A 1C83A 2VEXA 4QUNA 1LQFA 2HNPA 1ZZWA 1G4US 2P4DA 2CNFA 3MOZA 2I4GA 1PTVA 1XM2A 3I80A 1ONZA 4D3RA 3S3FA 2QBPA 4D3PA 2NTAA 4H34A 4BJOA 5KA7A 2PQ5A 5MMZB 2PT0A 1PTTA 3QCJA 3A5JA 1WAXA 2J17A 1G1HA 2FH7A 3BRHA 3CM3A 1GFYA 4AZ1A 4ICZA 1WCHA 1NWEA 2B3OA 2P6XA 1C86A 2DXPA 3U96A 3QCLA 1G4WR 4B04A 3QKPA 2PBNA 1L8KA 1YWFA 1NWLA 2BIJA 4HJQA 3SMEA 2I4HA 3A5KA 2G59A 2I6PA 3SR9A 2H4KA 4JMJA 3ZM3A 1Q1MA 1RPMA 2I6JA 2HC1A 3M4UA 1YGRA 2F70A 2B4UA 5K23A 1OEUA 3QCBA 4GE5A 2BZLA 2H04A 1XXPA 2OC3A 3RO1A 3ZV2A 3AWGA 1I9SA 2H4VA 5KA8A 3CWEA 2HC2A 5KA3A 2I5XA 3QCKA 4QAPA 4RH5A 2VEVA 2CMCA 4JMKA 1T48A 3D1HA 1PA1A 4Y14A 3S4EA 2HY3A 3EAXA 4WU3A 2CJZA 1OHCA 4RI5A 1FQ1A 5KA2A 2H4GA 2I1YA 2GWOA 1A5YA 2ESBA 4GWFA 2WGPA 3EZZA 1G7FA 4DGXA 5KADA 2Q47A 2CM3A 4NWGA 2G6ZA 4HRFA 1ZCLA 1PTUA 3QCMA 2PI7A 2H02A 2OOQA 3ZM1A 1GWZA 2GJTA 5BUGA 4GE2A 4YR8B 2HXPA 2HVLA 4ERCA 1Q6NA 1JLNA 3N0AA 3OLRA 1LARA 1I57A 3QCGA 1YTWA 5LXQB 2BGDA 2CM8A 2ZMMA 1P15A 3AWEA 2VEWA 1OEVA 5I6VA 1XXVA 2CNHA 1OETA 1C85A 1PTYA 2Q05A 4RHGA 4R0SA 4NWFA 4J51A 3QCDA 4WTYA 4MBBA 1YFOA 2I6IA 2I6MA 3O4UA 4R0TA 4RKKA 4GS0A 1C88A 3EB1A 5AWXA 4QBWA 2NLKA 3D9CA 1U26A 3F99A 1YZ4A 3D1QA 2AZRA 4OHHA 1J4XA 1U24A 4D3QA 5IBMA 3O5XA 2F6TA 4ZI4A 3B7OA 2NZ6A 2NT2A 3MMJA 5EHRA 1NL9A 2QDMA 2GP0A 5KABA 5EHPA 2I4EA 1C87A 3O4SA 5K9WA 3I7ZA 4GRZA 1KAVA 2Y96A 4DGPA 2H03A 4GRYA 1G7GA 3S3KA 2I3UA 3D44A 4WU2A 4NNDA 3V0FA 1VHRA 1EEOA 1ZCKA 4OHDA 4H1OA 5K22A 5KA9A 3H2XA 4RH9A 2B4OA 2QCJA 3RGQA 5J8RA 2JJDA 2QBSA 2CNGA 1R6HA 1OESA 3NMEA 1OHDA 2ZN7A 4OHEA 3QCNA 1G1FA 3QKQA 4IKCA 3ZMPA 2B07A 2FJNA 2QDCA 3O4TA 2VEYA 3V0JA 3EMUA 1YTSA 4TVVA 2E0TA 2R0BA 1X24A 2MBCA 2J16B 1ONYA 5BZZA 4KYRA 4S0GA 1RXDA 3QCCA 2HB1A 2QEPA 3F9AA 2QDPA 5KA0A 2QBRA 4R30A 3F9BA 2QBQA 4RDDA 4PVGA 4GE6A 4NX8A 2I42A 2Y2FA 3F41A 3OMHA 2F6FA 4Z6BA 5K25A 3ZM0A 2I3RA 2BV5A 3GXGA 2F46A 2C7SA 1T49A 4RI4A 1XBOA 1EENA 4QBEA 4QUMA 3I36A 2I6OA 5HDEA 1PXHA 3D1OA 2C46A 2CM7A 1BZCA 3EU0A 2NT7A 2OUDA 1OHEA 4JNBA 4ZN5A 5M43A 4PYHA 2AHSA 4WOHA 1U25A 5KAAA 3QCHA 1YPTA 2CNEA 5GTJA 5BZXA 3MOWA 1PYNA 3V0DA 2F6VA 5KACA 4Y2EA 3ZM2A 4JBCA 4QAHA 5BX1A 1Q6TA 4ZRTA 2B49A 1FPRA 3S3HA 3V0EA 3QCIA 1T4JA 3BLUA 2VEUA 3QCEA 2SHPA 1YN9A 1FPZA 5KA4A 1Q6JA 2IMGA 2OZ5A 5K9VA 1SUGA 1AAXA 1V3AA 2M3VA 3RZ2A 3BM8A 2J16A 2YDUA 3S4OA 2B4SA 1OEOX 2CM2A 1G1GA 1ZC0A 3AWFA 3LJ8A 4KI9A 1XRIA 2B4PA 1ECVA 3V0IA 2PA5A 2QCTA 3F81A 1WRMA 1LYVA 4OHLA 4NYHA 1NZ7A 4I8NA 1L8GA 3RGOA 4KYQA 2F6WA 1PA9A 1QXKA 1PH0A 2HNQA 1BZHA 2BGEA 3QCFA 1OEMX 1YGUA 4BPCA 1D5RA 1Q6MA 3GXHA 2RF6A 3ZMQA 2NV5A 5KA1A 1NNYA 1Q6SA 1JF7A 3D42A 1KAKA 4YAAA 2PSZA 1M3GA 2F6YA 3V0GA
chains in the Genus database with same CATH superfamily
4HJPA 4OHIA 1YTNA 3S3EA 4ZIYA 2CMBA 5IBSA 2X5OA 3PS5A 1I9TA 1BZJA 1MKPA 1P31A 2A8BA 1Q6PA 2HCMA 2A3KA 4GFUA 3V0HA 2FJMA 2CFVA 2CNIA 3BLTA 3O3LA 5K24A 1NO6A 2F6ZA 4GFVA 1QZ0A 2F71A 2VOSA 2JFGA 3N2AA 2CMAA 1C84A 2I75A 1C83A 2VEXA 4QUNA 1LQFA 2HNPA 1ZZWA 1G4US 2P4DA 2CNFA 3MOZA 2I4GA 1PTVA 2WJPA 1XM2A 3I80A 1ONZA 4D3RA 3S3FA 2QBPA 4D3PA 2NTAA 4H34A 4BJOA 5KA7A 2PQ5A 2GC6A 2PT0A 5MMZB 1PTTA 3QCJA 3A5JA 1WAXA 2J17A 1G1HA 2FH7A 4C13A 3BRHA 4BUCA 3CM3A 1GFYA 4AZ1A 4ICZA 1WCHA 1NWEA 2B3OA 2P6XA 1C86A 2DXPA 3U96A 3QCLA 1G4WR 2VTEA 4B04A 3QKPA 2PBNA 1L8KA 1YWFA 1NWLA 2BIJA 4HJQA 3SMEA 2F00A 2I4HA 3A5KA 2G59A 2I6PA 3SR9A 2WTZA 2H4KA 1E8CA 4JMJA 3ZM3A 1Q1MA 1RPMA 2I6JA 2HC1A 3M4UA 1YGRA 2GCAA 2F70A 2B4UA 5K23A 1OEUA 1JBWA 3QCBA 4GE5A 2BZLA 2H04A 1XXPA 2OC3A 3RO1A 3ZV2A 3AWGA 1I9SA 4HV4A 2H4VA 5KA8A 2Y1OA 3CWEA 2HC2A 5KA3A 2I5XA 3QCKA 4QAPA 4RH5A 2VEVA 2CMCA 4JMKA 1T48A 3D1HA 1PA1A 4Y14A 3S4EA 2HY3A 3EAXA 4C12A 4WU3A 2CJZA 1OHCA 4RI5A 1FQ1A 5KA2A 2H4GA 2I1YA 2GWOA 1A5YA 2ESBA 4GWFA 2WGPA 3EZZA 1G7FA 4DGXA 5KADA 2Q47A 2CM3A 4NWGA 2G6ZA 4HRFA 1ZCLA 1PTUA 3QCMA 2PI7A 2H02A 2OOQA 3ZM1A 1EEHA 1GWZA 2GJTA 2Y67A 5BUGA 4GE2A 4YR8B 2HXPA 1GG4A 2HVLA 4ERCA 1Q6NA 1JLNA 3HN7A 3N0AA 3OLRA 3ZL8A 1LARA 1I57A 3QCGA 1YTWA 5LXQB 2BGDA 2CM8A 4CVLA 2ZMMA 1P15A 3AWEA 2VEWA 1OEVA 5I6VA 1XXVA 2CNHA 1OETA 1C85A 1PTYA 2Q05A 4UAGA 4RHGA 4R0SA 4NWFA 4J51A 3QCDA 4WTYA 4MBBA 1YFOA 2I6IA 2I6MA 3O4UA 4R0TA 4RKKA 4GS0A 2JFHA 1C88A 4CVMA 3EB1A 5AWXA 1W7KA 5A5EA 4QBWA 4QDIA 2NLKA 2VTDA 3D9CA 2XPCA 1U26A 3F99A 1YZ4A 3D1QA 2UUPA 2AZRA 3NRSA 1J4XA 1U24A 4OHHA 2GCBA 4D3QA 5IBMA 3O5XA 2F6TA 1E0DA 4ZI4A 3B7OA 2NZ6A 2NT2A 3MMJA 5EHRA 1NL9A 2QDMA 4CVKA 2GP0A 5KABA 5EHPA 2I4EA 1C87A 3O4SA 5K9WA 3I7ZA 4GRZA 1KAVA 1FGSA 2Y96A 4DGPA 2H03A 4GRYA 1G7GA 3S3KA 2I3UA 3D44A 4WU2A 4NNDA 3V0FA 1VHRA 3ZM6A 1EEOA 1ZCKA 4OHDA 4H1OA 5K22A 5KA9A 2Y66A 3H2XA 4RH9A 2B4OA 2QCJA 3RGQA 5J8RA 2JJDA 1W78A 2QBSA 2CNGA 1R6HA 2XJAA 2Y68A 1OESA 3NMEA 1OHDA 2ZN7A 4OHEA 4QF5A 3QCNA 1G1FA 3QKQA 2GC5A 4IKCA 3ZMPA 2B07A 2FJNA 2QDCA 3O4TA 2VEYA 3V0JA 3EMUA 1YTSA 4TVVA 2E0TA 2R0BA 1X24A 2MBCA 3PYZA 2J16B 1ONYA 5BZZA 4KYRA 4S0GA 1RXDA 3QCCA 1UAGA 2HB1A 2QEPA 2UAGA 3F9AA 2QDPA 5KA0A 2QBRA 2JFFA 4R30A 3QCZA 3F9BA 2QBQA 4RDDA 4PVGA 4GE6A 4NX8A 2I42A 2Y2FA 3F41A 3OMHA 2F6FA 4Z6BA 5K25A 3MVNA 3ZM0A 2I3RA 2BV5A 3GXGA 2F46A 2C7SA 1T49A 2AM1A 4RI4A 3ZM5A 1J6UA 1XBOA 1EENA 4QBEA 4QUMA 3I36A 2I6OA 5HDEA 1PXHA 3UAGA 3D1OA 2C46A 2CM7A 1BZCA 3EU0A 2NT7A 2OUDA 1OHEA 4JNBA 4ZN5A 5M43A 4PYHA 2AHSA 4WOHA 1U25A 1GQYA 5KAAA 3QCHA 1YPTA 2CNEA 4BUBA 5GTJA 5BZXA 3MOWA 1PYNA 3V0DA 2F6VA 5KACA 4Y2EA 3ZM2A 4JBCA 4QAHA 5BX1A 1Q6TA 4ZRTA 2B49A 1FPRA 3S3HA 3V0EA 1P3DA 3QCIA 1T4JA 3BLUA 2VEUA 2UUOA 3QCEA 2SHPA 1YN9A 2AM2A 1FPZA 5KA4A 1Q6JA 2IMGA 2OZ5A 5K9VA 1SUGA 1AAXA 1V3AA 2M3VA 3RZ2A 3BM8A 2J16A 2YDUA 1JBVA 3S4OA 2B4SA 1OEOX 2CM2A 1G1GA 1ZC0A 3AWFA 3LJ8A 2VORA 4KI9A 1XRIA 2B4PA 5A5FA 1ECVA 3V0IA 2PA5A 2QCTA 3F81A 1WRMA 3LK7A 1LYVA 4OHLA 1GQQA 4NYHA 1NZ7A 4I8NA 1L8GA 3RGOA 4KYQA 2F6WA 1PA9A 1QXKA 1PH0A 2HNQA 1BZHA 2BGEA 3QCFA 1OEMX 1YGUA 4BPCA 1D5RA 1Q6MA 3GXHA 1O5ZA 2RF6A 3ZMQA 2NV5A 5KA1A 1NNYA 1Q6SA 1JF7A 3D42A 1KAKA 4YAAA 2PSZA 1M3GA 2F6YA 3V0GA
chains in the Genus database with same CATH topology
4HJPA 4OHIA 1YTNA 3S3EA 2CMBA 5IBSA 3PS5A 1I9TA 1BZJA 1MKPA 2A8BA 1Q6PA 2HCMA 2A3KA 4GFUA 3V0HA 2FJMA 2CFVA 2CNIA 3BLTA 3O3LA 5K24A 1NO6A 2F6ZA 4GFVA 1QZ0A 2F71A 2CMAA 1C84A 2I75A 1C83A 2VEXA 4QUNA 1LQFA 2HNPA 1ZZWA 1G4US 2P4DA 2CNFA 3MOZA 2I4GA 1PTVA 1XM2A 3I80A 1ONZA 4D3RA 3S3FA 2QBPA 4D3PA 2NTAA 4H34A 4BJOA 5KA7A 2PQ5A 5MMZB 2PT0A 1PTTA 3QCJA 3A5JA 1WAXA 2J17A 1G1HA 2FH7A 3BRHA 3CM3A 1GFYA 4AZ1A 4ICZA 1WCHA 1NWEA 2B3OA 2P6XA 1C86A 2DXPA 3U96A 3QCLA 1G4WR 4B04A 3QKPA 2PBNA 1L8KA 1YWFA 1NWLA 2BIJA 4HJQA 3SMEA 2I4HA 3A5KA 2G59A 2I6PA 3SR9A 2H4KA 4JMJA 3ZM3A 1Q1MA 1RPMA 2I6JA 2HC1A 3M4UA 1YGRA 2F70A 2B4UA 5K23A 1OEUA 3QCBA 4GE5A 2BZLA 2H04A 1XXPA 2OC3A 3RO1A 3ZV2A 3AWGA 1I9SA 2H4VA 5KA8A 3CWEA 2HC2A 5KA3A 2I5XA 3QCKA 4QAPA 4RH5A 2VEVA 2CMCA 4JMKA 1T48A 3D1HA 1PA1A 4Y14A 3S4EA 2HY3A 3EAXA 4WU3A 2CJZA 1OHCA 4RI5A 1FQ1A 5KA2A 2H4GA 2I1YA 2GWOA 1A5YA 2ESBA 4GWFA 2WGPA 3EZZA 1G7FA 4DGXA 5KADA 2Q47A 2CM3A 4NWGA 2G6ZA 4HRFA 1ZCLA 1PTUA 3QCMA 2PI7A 2H02A 2OOQA 3ZM1A 1GWZA 2GJTA 5BUGA 4GE2A 4YR8B 2HXPA 2HVLA 4ERCA 1Q6NA 1JLNA 3N0AA 3OLRA 1LARA 1I57A 3QCGA 1YTWA 5LXQB 2BGDA 2CM8A 2ZMMA 1P15A 3AWEA 2VEWA 1OEVA 5I6VA 1XXVA 2CNHA 1OETA 1C85A 1PTYA 2Q05A 4RHGA 4R0SA 4NWFA 4J51A 3QCDA 4WTYA 4MBBA 1YFOA 2I6IA 2I6MA 3O4UA 4R0TA 4RKKA 4GS0A 1C88A 3EB1A 5AWXA 4QBWA 2NLKA 3D9CA 1U26A 3F99A 1YZ4A 3D1QA 2AZRA 4OHHA 1J4XA 1U24A 4D3QA 5IBMA 3O5XA 2F6TA 4ZI4A 3B7OA 2NZ6A 2NT2A 3MMJA 5EHRA 1NL9A 2QDMA 2GP0A 5KABA 5EHPA 2I4EA 1C87A 3O4SA 5K9WA 3I7ZA 4GRZA 1KAVA 2Y96A 4DGPA 2H03A 4GRYA 1G7GA 3S3KA 2I3UA 3D44A 4WU2A 4NNDA 3V0FA 1VHRA 1EEOA 1ZCKA 4OHDA 4H1OA 5K22A 5KA9A 3H2XA 4RH9A 2B4OA 2QCJA 3RGQA 5J8RA 2JJDA 2QBSA 2CNGA 1R6HA 1OESA 3NMEA 1OHDA 2ZN7A 4OHEA 3QCNA 1G1FA 3QKQA 4IKCA 3ZMPA 2B07A 2FJNA 2QDCA 3O4TA 2VEYA 3V0JA 3EMUA 1YTSA 4TVVA 2E0TA 2R0BA 1X24A 2MBCA 2J16B 1ONYA 5BZZA 4KYRA 4S0GA 1RXDA 3QCCA 2HB1A 2QEPA 3F9AA 2QDPA 5KA0A 2QBRA 4R30A 3F9BA 2QBQA 4RDDA 4PVGA 4GE6A 4NX8A 2I42A 2Y2FA 3F41A 3OMHA 2F6FA 4Z6BA 5K25A 3ZM0A 2I3RA 2BV5A 3GXGA 2F46A 2C7SA 1T49A 4RI4A 1XBOA 1EENA 4QBEA 4QUMA 3I36A 2I6OA 5HDEA 1PXHA 3D1OA 2C46A 2CM7A 1BZCA 3EU0A 2NT7A 2OUDA 1OHEA 4JNBA 4ZN5A 5M43A 4PYHA 2AHSA 4WOHA 1U25A 5KAAA 3QCHA 1YPTA 2CNEA 5GTJA 5BZXA 3MOWA 1PYNA 3V0DA 2F6VA 5KACA 4Y2EA 3ZM2A 4JBCA 4QAHA 5BX1A 1Q6TA 4ZRTA 2B49A 1FPRA 3S3HA 3V0EA 3QCIA 1T4JA 3BLUA 2VEUA 3QCEA 2SHPA 1YN9A 1FPZA 5KA4A 1Q6JA 2IMGA 2OZ5A 5K9VA 1SUGA 1AAXA 1V3AA 2M3VA 3RZ2A 3BM8A 2J16A 2YDUA 3S4OA 2B4SA 1OEOX 2CM2A 1G1GA 1ZC0A 3AWFA 3LJ8A 4KI9A 1XRIA 2B4PA 1ECVA 3V0IA 2PA5A 2QCTA 3F81A 1WRMA 1LYVA 4OHLA 4NYHA 1NZ7A 4I8NA 1L8GA 3RGOA 4KYQA 2F6WA 1PA9A 1QXKA 1PH0A 2HNQA 1BZHA 2BGEA 3QCFA 1OEMX 1YGUA 4BPCA 1D5RA 1Q6MA 3GXHA 2RF6A 3ZMQA 2NV5A 5KA1A 1NNYA 1Q6SA 1JF7A 3D42A 1KAKA 4YAAA 2PSZA 1M3GA 2F6YA 3V0GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HJP A;  4OHI A;  1YTN A;  3S3E A;  2CMB A;  5IBS A;  3PS5 A;  1I9T A;  1BZJ A;  1MKP A;  2A8B A;  1Q6P A;  2HCM A;  2A3K A;  4GFU A;  3V0H A;  2FJM A;  2CFV A;  2CNI A;  3BLT A;  3O3L A;  5K24 A;  1NO6 A;  2F6Z A;  4GFV A;  1QZ0 A;  2F71 A;  2CMA A;  1C84 A;  2I75 A;  1C83 A;  2VEX A;  4QUN A;  1LQF A;  2HNP A;  1ZZW A;  1G4U S;  2P4D A;  2CNF A;  3MOZ A;  2I4G A;  1PTV A;  1XM2 A;  3I80 A;  1ONZ A;  4D3R A;  3S3F A;  2QBP A;  4D3P A;  2NTA A;  4H34 A;  4BJO A;  5KA7 A;  2PQ5 A;  5MMZ B;  2PT0 A;  1PTT A;  3QCJ A;  3A5J A;  1WAX A;  2J17 A;  1G1H A;  2FH7 A;  3BRH A;  3CM3 A;  1GFY A;  4AZ1 A;  4ICZ A;  1WCH A;  1NWE A;  2B3O A;  2P6X A;  1C86 A;  2DXP A;  3U96 A;  3QCL A;  1G4W R;  4B04 A;  3QKP A;  2PBN A;  1L8K A;  1YWF A;  1NWL A;  2BIJ A;  4HJQ A;  3SME A;  2I4H A;  3A5K A;  2G59 A;  2I6P A;  3SR9 A;  2H4K A;  4JMJ A;  3ZM3 A;  1Q1M A;  1RPM A;  2I6J A;  2HC1 A;  3M4U A;  1YGR A;  2F70 A;  2B4U A;  5K23 A;  1OEU A;  3QCB A;  4GE5 A;  2BZL A;  2H04 A;  1XXP A;  2OC3 A;  3RO1 A;  3ZV2 A;  3AWG A;  1I9S A;  2H4V A;  5KA8 A;  3CWE A;  2HC2 A;  5KA3 A;  2I5X A;  3QCK A;  4QAP A;  4RH5 A;  2VEV A;  2CMC A;  4JMK A;  1T48 A;  3D1H A;  1PA1 A;  4Y14 A;  3S4E A;  2HY3 A;  3EAX A;  4WU3 A;  2CJZ A;  1OHC A;  4RI5 A;  1FQ1 A;  5KA2 A;  2H4G A;  2I1Y A;  2GWO A;  1A5Y A;  2ESB A;  4GWF A;  2WGP A;  3EZZ A;  1G7F A;  4DGX A;  5KAD A;  2Q47 A;  2CM3 A;  4NWG A;  2G6Z A;  4HRF A;  1ZCL A;  1PTU A;  3QCM A;  2PI7 A;  2H02 A;  2OOQ A;  3ZM1 A;  1GWZ A;  2GJT A;  5BUG A;  4GE2 A;  4YR8 B;  2HXP A;  2HVL A;  4ERC A;  1Q6N A;  1JLN A;  3N0A A;  3OLR A;  1LAR A;  1I57 A;  3QCG A;  1YTW A;  5LXQ B;  2BGD A;  2CM8 A;  2ZMM A;  1P15 A;  3AWE A;  2VEW A;  1OEV A;  5I6V A;  1XXV A;  2CNH A;  1OET A;  1C85 A;  1PTY A;  2Q05 A;  4RHG A;  4R0S A;  4NWF A;  4J51 A;  3QCD A;  4WTY A;  4MBB A;  1YFO A;  2I6I A;  2I6M A;  3O4U A;  4R0T A;  4RKK A;  4GS0 A;  1C88 A;  3EB1 A;  5AWX A;  4QBW A;  2NLK A;  3D9C A;  1U26 A;  3F99 A;  1YZ4 A;  3D1Q A;  2AZR A;  4OHH A;  1J4X A;  1U24 A;  4D3Q A;  5IBM A;  3O5X A;  2F6T A;  4ZI4 A;  3B7O A;  2NZ6 A;  2NT2 A;  3MMJ A;  5EHR A;  1NL9 A;  2QDM A;  2GP0 A;  5KAB A;  5EHP A;  2I4E A;  1C87 A;  3O4S A;  5K9W A;  3I7Z A;  4GRZ A;  1KAV A;  2Y96 A;  4DGP A;  2H03 A;  4GRY A;  1G7G A;  3S3K A;  2I3U A;  3D44 A;  4WU2 A;  4NND A;  3V0F A;  1VHR A;  1EEO A;  1ZCK A;  4OHD A;  4H1O A;  5K22 A;  5KA9 A;  3H2X A;  4RH9 A;  2B4O A;  2QCJ A;  3RGQ A;  5J8R A;  2JJD A;  2QBS A;  2CNG A;  1R6H A;  1OES A;  3NME A;  1OHD A;  2ZN7 A;  4OHE A;  3QCN A;  1G1F A;  3QKQ A;  4IKC A;  3ZMP A;  2B07 A;  2FJN A;  2QDC A;  3O4T A;  2VEY A;  3V0J A;  3EMU A;  1YTS A;  4TVV A;  2E0T A;  2R0B A;  1X24 A;  2MBC A;  2J16 B;  1ONY A;  5BZZ A;  4KYR A;  4S0G A;  1RXD A;  3QCC A;  2HB1 A;  2QEP A;  3F9A A;  2QDP A;  5KA0 A;  2QBR A;  4R30 A;  3F9B A;  2QBQ A;  4RDD A;  4PVG A;  4GE6 A;  4NX8 A;  2I42 A;  2Y2F A;  3F41 A;  3OMH A;  2F6F A;  4Z6B A;  5K25 A;  3ZM0 A;  2I3R A;  2BV5 A;  3GXG A;  2F46 A;  2C7S A;  1T49 A;  4RI4 A;  1XBO A;  1EEN A;  4QBE A;  4QUM A;  3I36 A;  2I6O A;  5HDE A;  1PXH A;  3D1O A;  2C46 A;  2CM7 A;  1BZC A;  3EU0 A;  2NT7 A;  2OUD A;  1OHE A;  4JNB A;  4ZN5 A;  5M43 A;  4PYH A;  2AHS A;  4WOH A;  1U25 A;  5KAA A;  3QCH A;  1YPT A;  2CNE A;  5GTJ A;  5BZX A;  3MOW A;  1PYN A;  3V0D A;  2F6V A;  5KAC A;  4Y2E A;  3ZM2 A;  4JBC A;  4QAH A;  5BX1 A;  1Q6T A;  4ZRT A;  2B49 A;  1FPR A;  3S3H A;  3V0E A;  3QCI A;  1T4J A;  3BLU A;  2VEU A;  3QCE A;  2SHP A;  1YN9 A;  1FPZ A;  5KA4 A;  1Q6J A;  2IMG A;  2OZ5 A;  5K9V A;  1SUG A;  1AAX A;  1V3A A;  2M3V A;  3RZ2 A;  3BM8 A;  2J16 A;  2YDU A;  3S4O A;  2B4S A;  1OEO X;  2CM2 A;  1G1G A;  1ZC0 A;  3AWF A;  3LJ8 A;  4KI9 A;  1XRI A;  2B4P A;  1ECV A;  3V0I A;  2PA5 A;  2QCT A;  3F81 A;  1WRM A;  1LYV A;  4OHL A;  4NYH A;  1NZ7 A;  4I8N A;  1L8G A;  3RGO A;  4KYQ A;  2F6W A;  1PA9 A;  1QXK A;  1PH0 A;  2HNQ A;  1BZH A;  2BGE A;  3QCF A;  1OEM X;  1YGU A;  4BPC A;  1D5R A;  1Q6M A;  3GXH A;  2RF6 A;  3ZMQ A;  2NV5 A;  5KA1 A;  1NNY A;  1Q6S A;  1JF7 A;  3D42 A;  1KAK A;  4YAA A;  2PSZ A;  1M3G A;  2F6Y A;  3V0G A; 
#chains in the Genus database with same CATH topology
 4HJP A;  4OHI A;  1YTN A;  3S3E A;  4ZIY A;  2CMB A;  5IBS A;  2X5O A;  3PS5 A;  1I9T A;  1BZJ A;  1MKP A;  1P31 A;  2A8B A;  1Q6P A;  2HCM A;  2A3K A;  4GFU A;  3V0H A;  2FJM A;  2CFV A;  2CNI A;  3BLT A;  3O3L A;  5K24 A;  1NO6 A;  2F6Z A;  4GFV A;  1QZ0 A;  2F71 A;  2VOS A;  2JFG A;  3N2A A;  2CMA A;  1C84 A;  2I75 A;  1C83 A;  2VEX A;  4QUN A;  1LQF A;  2HNP A;  1ZZW A;  1G4U S;  2P4D A;  2CNF A;  3MOZ A;  2I4G A;  1PTV A;  2WJP A;  1XM2 A;  3I80 A;  1ONZ A;  4D3R A;  3S3F A;  2QBP A;  4D3P A;  2NTA A;  4H34 A;  4BJO A;  5KA7 A;  2PQ5 A;  2GC6 A;  2PT0 A;  5MMZ B;  1PTT A;  3QCJ A;  3A5J A;  1WAX A;  2J17 A;  1G1H A;  2FH7 A;  4C13 A;  3BRH A;  4BUC A;  3CM3 A;  1GFY A;  4AZ1 A;  4ICZ A;  1WCH A;  1NWE A;  2B3O A;  2P6X A;  1C86 A;  2DXP A;  3U96 A;  3QCL A;  1G4W R;  2VTE A;  4B04 A;  3QKP A;  2PBN A;  1L8K A;  1YWF A;  1NWL A;  2BIJ A;  4HJQ A;  3SME A;  2F00 A;  2I4H A;  3A5K A;  2G59 A;  2I6P A;  3SR9 A;  2WTZ A;  2H4K A;  1E8C A;  4JMJ A;  3ZM3 A;  1Q1M A;  1RPM A;  2I6J A;  2HC1 A;  3M4U A;  1YGR A;  2GCA A;  2F70 A;  2B4U A;  5K23 A;  1OEU A;  1JBW A;  3QCB A;  4GE5 A;  2BZL A;  2H04 A;  1XXP A;  2OC3 A;  3RO1 A;  3ZV2 A;  3AWG A;  1I9S A;  4HV4 A;  2H4V A;  5KA8 A;  2Y1O A;  3CWE A;  2HC2 A;  5KA3 A;  2I5X A;  3QCK A;  4QAP A;  4RH5 A;  2VEV A;  2CMC A;  4JMK A;  1T48 A;  3D1H A;  1PA1 A;  4Y14 A;  3S4E A;  2HY3 A;  3EAX A;  4C12 A;  4WU3 A;  2CJZ A;  1OHC A;  4RI5 A;  1FQ1 A;  5KA2 A;  2H4G A;  2I1Y A;  2GWO A;  1A5Y A;  2ESB A;  4GWF A;  2WGP A;  3EZZ A;  1G7F A;  4DGX A;  5KAD A;  2Q47 A;  2CM3 A;  4NWG A;  2G6Z A;  4HRF A;  1ZCL A;  1PTU A;  3QCM A;  2PI7 A;  2H02 A;  2OOQ A;  3ZM1 A;  1EEH A;  1GWZ A;  2GJT A;  2Y67 A;  5BUG A;  4GE2 A;  4YR8 B;  2HXP A;  1GG4 A;  2HVL A;  4ERC A;  1Q6N A;  1JLN A;  3HN7 A;  3N0A A;  3OLR A;  3ZL8 A;  1LAR A;  1I57 A;  3QCG A;  1YTW A;  5LXQ B;  2BGD A;  2CM8 A;  4CVL A;  2ZMM A;  1P15 A;  3AWE A;  2VEW A;  1OEV A;  5I6V A;  1XXV A;  2CNH A;  1OET A;  1C85 A;  1PTY A;  2Q05 A;  4UAG A;  4RHG A;  4R0S A;  4NWF A;  4J51 A;  3QCD A;  4WTY A;  4MBB A;  1YFO A;  2I6I A;  2I6M A;  3O4U A;  4R0T A;  4RKK A;  4GS0 A;  2JFH A;  1C88 A;  4CVM A;  3EB1 A;  5AWX A;  1W7K A;  5A5E A;  4QBW A;  4QDI A;  2NLK A;  2VTD A;  3D9C A;  2XPC A;  1U26 A;  3F99 A;  1YZ4 A;  3D1Q A;  2UUP A;  2AZR A;  3NRS A;  1J4X A;  1U24 A;  4OHH A;  2GCB A;  4D3Q A;  5IBM A;  3O5X A;  2F6T A;  1E0D A;  4ZI4 A;  3B7O A;  2NZ6 A;  2NT2 A;  3MMJ A;  5EHR A;  1NL9 A;  2QDM A;  4CVK A;  2GP0 A;  5KAB A;  5EHP A;  2I4E A;  1C87 A;  3O4S A;  5K9W A;  3I7Z A;  4GRZ A;  1KAV A;  1FGS A;  2Y96 A;  4DGP A;  2H03 A;  4GRY A;  1G7G A;  3S3K A;  2I3U A;  3D44 A;  4WU2 A;  4NND A;  3V0F A;  1VHR A;  3ZM6 A;  1EEO A;  1ZCK A;  4OHD A;  4H1O A;  5K22 A;  5KA9 A;  2Y66 A;  3H2X A;  4RH9 A;  2B4O A;  2QCJ A;  3RGQ A;  5J8R A;  2JJD A;  1W78 A;  2QBS A;  2CNG A;  1R6H A;  2XJA A;  2Y68 A;  1OES A;  3NME A;  1OHD A;  2ZN7 A;  4OHE A;  4QF5 A;  3QCN A;  1G1F A;  3QKQ A;  2GC5 A;  4IKC A;  3ZMP A;  2B07 A;  2FJN A;  2QDC A;  3O4T A;  2VEY A;  3V0J A;  3EMU A;  1YTS A;  4TVV A;  2E0T A;  2R0B A;  1X24 A;  2MBC A;  3PYZ A;  2J16 B;  1ONY A;  5BZZ A;  4KYR A;  4S0G A;  1RXD A;  3QCC A;  1UAG A;  2HB1 A;  2QEP A;  2UAG A;  3F9A A;  2QDP A;  5KA0 A;  2QBR A;  2JFF A;  4R30 A;  3QCZ A;  3F9B A;  2QBQ A;  4RDD A;  4PVG A;  4GE6 A;  4NX8 A;  2I42 A;  2Y2F A;  3F41 A;  3OMH A;  2F6F A;  4Z6B A;  5K25 A;  3MVN A;  3ZM0 A;  2I3R A;  2BV5 A;  3GXG A;  2F46 A;  2C7S A;  1T49 A;  2AM1 A;  4RI4 A;  3ZM5 A;  1J6U A;  1XBO A;  1EEN A;  4QBE A;  4QUM A;  3I36 A;  2I6O A;  5HDE A;  1PXH A;  3UAG A;  3D1O A;  2C46 A;  2CM7 A;  1BZC A;  3EU0 A;  2NT7 A;  2OUD A;  1OHE A;  4JNB A;  4ZN5 A;  5M43 A;  4PYH A;  2AHS A;  4WOH A;  1U25 A;  1GQY A;  5KAA A;  3QCH A;  1YPT A;  2CNE A;  4BUB A;  5GTJ A;  5BZX A;  3MOW A;  1PYN A;  3V0D A;  2F6V A;  5KAC A;  4Y2E A;  3ZM2 A;  4JBC A;  4QAH A;  5BX1 A;  1Q6T A;  4ZRT A;  2B49 A;  1FPR A;  3S3H A;  3V0E A;  1P3D A;  3QCI A;  1T4J A;  3BLU A;  2VEU A;  2UUO A;  3QCE A;  2SHP A;  1YN9 A;  2AM2 A;  1FPZ A;  5KA4 A;  1Q6J A;  2IMG A;  2OZ5 A;  5K9V A;  1SUG A;  1AAX A;  1V3A A;  2M3V A;  3RZ2 A;  3BM8 A;  2J16 A;  2YDU A;  1JBV A;  3S4O A;  2B4S A;  1OEO X;  2CM2 A;  1G1G A;  1ZC0 A;  3AWF A;  3LJ8 A;  2VOR A;  4KI9 A;  1XRI A;  2B4P A;  5A5F A;  1ECV A;  3V0I A;  2PA5 A;  2QCT A;  3F81 A;  1WRM A;  3LK7 A;  1LYV A;  4OHL A;  1GQQ A;  4NYH A;  1NZ7 A;  4I8N A;  1L8G A;  3RGO A;  4KYQ A;  2F6W A;  1PA9 A;  1QXK A;  1PH0 A;  2HNQ A;  1BZH A;  2BGE A;  3QCF A;  1OEM X;  1YGU A;  4BPC A;  1D5R A;  1Q6M A;  3GXH A;  1O5Z A;  2RF6 A;  3ZMQ A;  2NV5 A;  5KA1 A;  1NNY A;  1Q6S A;  1JF7 A;  3D42 A;  1KAK A;  4YAA A;  2PSZ A;  1M3G A;  2F6Y A;  3V0G A; 
#chains in the Genus database with same CATH homology
 4HJP A;  4OHI A;  1YTN A;  3S3E A;  2CMB A;  5IBS A;  3PS5 A;  1I9T A;  1BZJ A;  1MKP A;  2A8B A;  1Q6P A;  2HCM A;  2A3K A;  4GFU A;  3V0H A;  2FJM A;  2CFV A;  2CNI A;  3BLT A;  3O3L A;  5K24 A;  1NO6 A;  2F6Z A;  4GFV A;  1QZ0 A;  2F71 A;  2CMA A;  1C84 A;  2I75 A;  1C83 A;  2VEX A;  4QUN A;  1LQF A;  2HNP A;  1ZZW A;  1G4U S;  2P4D A;  2CNF A;  3MOZ A;  2I4G A;  1PTV A;  1XM2 A;  3I80 A;  1ONZ A;  4D3R A;  3S3F A;  2QBP A;  4D3P A;  2NTA A;  4H34 A;  4BJO A;  5KA7 A;  2PQ5 A;  5MMZ B;  2PT0 A;  1PTT A;  3QCJ A;  3A5J A;  1WAX A;  2J17 A;  1G1H A;  2FH7 A;  3BRH A;  3CM3 A;  1GFY A;  4AZ1 A;  4ICZ A;  1WCH A;  1NWE A;  2B3O A;  2P6X A;  1C86 A;  2DXP A;  3U96 A;  3QCL A;  1G4W R;  4B04 A;  3QKP A;  2PBN A;  1L8K A;  1YWF A;  1NWL A;  2BIJ A;  4HJQ A;  3SME A;  2I4H A;  3A5K A;  2G59 A;  2I6P A;  3SR9 A;  2H4K A;  4JMJ A;  3ZM3 A;  1Q1M A;  1RPM A;  2I6J A;  2HC1 A;  3M4U A;  1YGR A;  2F70 A;  2B4U A;  5K23 A;  1OEU A;  3QCB A;  4GE5 A;  2BZL A;  2H04 A;  1XXP A;  2OC3 A;  3RO1 A;  3ZV2 A;  3AWG A;  1I9S A;  2H4V A;  5KA8 A;  3CWE A;  2HC2 A;  5KA3 A;  2I5X A;  3QCK A;  4QAP A;  4RH5 A;  2VEV A;  2CMC A;  4JMK A;  1T48 A;  3D1H A;  1PA1 A;  4Y14 A;  3S4E A;  2HY3 A;  3EAX A;  4WU3 A;  2CJZ A;  1OHC A;  4RI5 A;  1FQ1 A;  5KA2 A;  2H4G A;  2I1Y A;  2GWO A;  1A5Y A;  2ESB A;  4GWF A;  2WGP A;  3EZZ A;  1G7F A;  4DGX A;  5KAD A;  2Q47 A;  2CM3 A;  4NWG A;  2G6Z A;  4HRF A;  1ZCL A;  1PTU A;  3QCM A;  2PI7 A;  2H02 A;  2OOQ A;  3ZM1 A;  1GWZ A;  2GJT A;  5BUG A;  4GE2 A;  4YR8 B;  2HXP A;  2HVL A;  4ERC A;  1Q6N A;  1JLN A;  3N0A A;  3OLR A;  1LAR A;  1I57 A;  3QCG A;  1YTW A;  5LXQ B;  2BGD A;  2CM8 A;  2ZMM A;  1P15 A;  3AWE A;  2VEW A;  1OEV A;  5I6V A;  1XXV A;  2CNH A;  1OET A;  1C85 A;  1PTY A;  2Q05 A;  4RHG A;  4R0S A;  4NWF A;  4J51 A;  3QCD A;  4WTY A;  4MBB A;  1YFO A;  2I6I A;  2I6M A;  3O4U A;  4R0T A;  4RKK A;  4GS0 A;  1C88 A;  3EB1 A;  5AWX A;  4QBW A;  2NLK A;  3D9C A;  1U26 A;  3F99 A;  1YZ4 A;  3D1Q A;  2AZR A;  4OHH A;  1J4X A;  1U24 A;  4D3Q A;  5IBM A;  3O5X A;  2F6T A;  4ZI4 A;  3B7O A;  2NZ6 A;  2NT2 A;  3MMJ A;  5EHR A;  1NL9 A;  2QDM A;  2GP0 A;  5KAB A;  5EHP A;  2I4E A;  1C87 A;  3O4S A;  5K9W A;  3I7Z A;  4GRZ A;  1KAV A;  2Y96 A;  4DGP A;  2H03 A;  4GRY A;  1G7G A;  3S3K A;  2I3U A;  3D44 A;  4WU2 A;  4NND A;  3V0F A;  1VHR A;  1EEO A;  1ZCK A;  4OHD A;  4H1O A;  5K22 A;  5KA9 A;  3H2X A;  4RH9 A;  2B4O A;  2QCJ A;  3RGQ A;  5J8R A;  2JJD A;  2QBS A;  2CNG A;  1R6H A;  1OES A;  3NME A;  1OHD A;  2ZN7 A;  4OHE A;  3QCN A;  1G1F A;  3QKQ A;  4IKC A;  3ZMP A;  2B07 A;  2FJN A;  2QDC A;  3O4T A;  2VEY A;  3V0J A;  3EMU A;  1YTS A;  4TVV A;  2E0T A;  2R0B A;  1X24 A;  2MBC A;  2J16 B;  1ONY A;  5BZZ A;  4KYR A;  4S0G A;  1RXD A;  3QCC A;  2HB1 A;  2QEP A;  3F9A A;  2QDP A;  5KA0 A;  2QBR A;  4R30 A;  3F9B A;  2QBQ A;  4RDD A;  4PVG A;  4GE6 A;  4NX8 A;  2I42 A;  2Y2F A;  3F41 A;  3OMH A;  2F6F A;  4Z6B A;  5K25 A;  3ZM0 A;  2I3R A;  2BV5 A;  3GXG A;  2F46 A;  2C7S A;  1T49 A;  4RI4 A;  1XBO A;  1EEN A;  4QBE A;  4QUM A;  3I36 A;  2I6O A;  5HDE A;  1PXH A;  3D1O A;  2C46 A;  2CM7 A;  1BZC A;  3EU0 A;  2NT7 A;  2OUD A;  1OHE A;  4JNB A;  4ZN5 A;  5M43 A;  4PYH A;  2AHS A;  4WOH A;  1U25 A;  5KAA A;  3QCH A;  1YPT A;  2CNE A;  5GTJ A;  5BZX A;  3MOW A;  1PYN A;  3V0D A;  2F6V A;  5KAC A;  4Y2E A;  3ZM2 A;  4JBC A;  4QAH A;  5BX1 A;  1Q6T A;  4ZRT A;  2B49 A;  1FPR A;  3S3H A;  3V0E A;  3QCI A;  1T4J A;  3BLU A;  2VEU A;  3QCE A;  2SHP A;  1YN9 A;  1FPZ A;  5KA4 A;  1Q6J A;  2IMG A;  2OZ5 A;  5K9V A;  1SUG A;  1AAX A;  1V3A A;  2M3V A;  3RZ2 A;  3BM8 A;  2J16 A;  2YDU A;  3S4O A;  2B4S A;  1OEO X;  2CM2 A;  1G1G A;  1ZC0 A;  3AWF A;  3LJ8 A;  4KI9 A;  1XRI A;  2B4P A;  1ECV A;  3V0I A;  2PA5 A;  2QCT A;  3F81 A;  1WRM A;  1LYV A;  4OHL A;  4NYH A;  1NZ7 A;  4I8N A;  1L8G A;  3RGO A;  4KYQ A;  2F6W A;  1PA9 A;  1QXK A;  1PH0 A;  2HNQ A;  1BZH A;  2BGE A;  3QCF A;  1OEM X;  1YGU A;  4BPC A;  1D5R A;  1Q6M A;  3GXH A;  2RF6 A;  3ZMQ A;  2NV5 A;  5KA1 A;  1NNY A;  1Q6S A;  1JF7 A;  3D42 A;  1KAK A;  4YAA A;  2PSZ A;  1M3G A;  2F6Y A;  3V0G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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