2I4GA

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with a sulfamic acid (soaking experiment)
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
293
structure length
289
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase beta
total genus 100
structure length 289
sequence length 293
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2i4gA00
3V0JA 2F71A 1P15A 2B4SA 1C88A 2RF6A 3D44A 3S3EA 2Y2FA 2H02A 4OHIA 2F6FA 1OESA 2AZRA 3O5XA 2VEYA 3ZM3A 2ZMMA 1KAVA 4QUNA 3S3KA 3EMUA 5GTJA 3EAXA 3EB1A 3NMEA 2H4KA 1Q6NA 1FPZA 2I4GA 5KADA 4ERCA 4MBBA 3RGQA 3I80A 2FJMA 2OOQA 4GFUA 2HC2A 4JBCA 2BIJA 2NTAA 1X24A 2CNEA 3ZM1A 2J17A 2HNQA 2IMGA 2F6WA 3S4OA 5KACA 1C86A 2HCMA 5K25A 1OHDA 3H2XA 1RXDA 1OEVA 1G1GA 2H04A 1ONZA 2Y96A 1XM2A 1YTWA 2HY3A 4NWGA 1AAXA 4HJPA 1C87A 3ZMQA 1OEOX 5K23A 2PI7A 1Q1MA 1ZCLA 2I1YA 4NX8A 3OMHA 1T48A 1QXKA 1YTNA 4D3PA 1PTTA 2CNHA 2JJDA 5KA1A 3QCJA 2CM7A 4HJQA 1T49A 1FPRA 3SR9A 2SHPA 2M3VA 3V0EA 2NT7A 4H34A 3V0HA 5BUGA 2H4GA 3A5KA 3QCBA 2I3RA 2BGDA 2QBQA 1MKPA 1I9TA 1C83A 3LJ8A 4OHEA 2I6IA 1G7FA 2PA5A 1A5YA 3BRHA 2I6OA 4JNBA 1PA9A 1BZCA 3I7ZA 1G7GA 1WCHA 2VEWA 2PQ5A 3U96A 2B3OA 2QBPA 1PYNA 3ZV2A 2B4UA 2I6PA 1PH0A 4DGPA 1OHEA 1G1FA 4RI5A 1I9SA 2F6YA 1OETA 3B7OA 2FJNA 3D42A 1EENA 1ZC0A 3QCCA 2HVLA 3F9BA 1NWEA 1PTYA 5BZXA 2PT0A 4B04A 5BX1A 3V0IA 2CMBA 4KYRA 2P4DA 1XBOA 3QCMA 2Q05A 4OHDA 3QCNA 4GWFA 4RI4A 4GE6A 1C84A 2QDPA 1PTUA 3BLUA 3CWEA 1ZZWA 2QCTA 1M3GA 3F9AA 3QCGA 2NV5A 4D3QA 1YFOA 3AWGA 4H1OA 4Y2EA 1U25A 4IKCA 2QBSA 4WU2A 3PS5A 2VEUA 2I75A 4GS0A 2CFVA 2H4VA 2QCJA 1OHCA 1XRIA 2HXPA 5M43A 4GE5A 2CM8A 1PA1A 2H03A 2CM3A 1U26A 5I6VA 1QZ0A 4AZ1A 3GXHA 2FH7A 1YTSA 3ZMPA 3A5JA 2B4PA 5K9VA 3BM8A 4QBEA 3S3FA 1JF7A 1PTVA 3V0DA 5IBMA 2QDCA 1Q6JA 5KA7A 2NLKA 5KA0A 5IBSA 4WTYA 1JLNA 3D1QA 1Q6PA 3S4EA 2CNIA 5EHRA 2PBNA 4OHLA 4RHGA 1SUGA 4RKKA 3MOWA 3QCEA 1C85A 3RZ2A 1ZCKA 4QUMA 1YGRA 5K9WA 4RH9A 1NNYA 2HC1A 1BZJA 2C7SA 3F99A 3O4TA 5KA3A 5KAAA 4R30A 3AWEA 4GE2A 2B07A 1FQ1A 2I6MA 4ICZA 1NWLA 2CM2A 2GJTA 1ECVA 2Q47A 2DXPA 3V0GA 2NT2A 2G6ZA 3S3HA 3D1HA 3O4SA 2GP0A 3EZZA 1G1HA 5BZZA 4BJOA 5KABA 1XXPA 5J8RA 1Q6TA 1VHRA 4GFVA 4QAHA 4RDDA 2CMCA 4HRFA 4R0TA 3BLTA 2QBRA 4GRYA 2J16A 4ZRTA 4JMJA 2BGEA 1G4US 4PVGA 4YAAA 1XXVA 2G59A 3QCFA 1EEOA 2CJZA 2I42A 2YDUA 2B4OA 3GXGA 2MBCA 3MMJA 2OZ5A 2QEPA 2J16B 1WRMA 2GWOA 2HNPA 4D3RA 1U24A 2P6XA 2OC3A 4NNDA 2A8BA 3OLRA 1OEMX 1R6HA 4KYQA 4ZI4A 1OEUA 5HDEA 1YN9A 3D1OA 2F6VA 2I4EA 4GRZA 1YPTA 4J51A 2NZ6A 1V3AA 3CM3A 1NL9A 3QCDA 5KA2A 2I3UA 1LQFA 3D9CA 3N0AA 1YWFA 3QCLA 1NZ7A 2BZLA 2F6ZA 4JMKA 4BPCA 1NO6A 3SMEA 1T4JA 3QKQA 1Q6SA 4QBWA 3ZM0A 2F70A 2ESBA 3QCKA 4OHHA 4PYHA 5EHPA 3F41A 4DGXA 1J4XA 4NYHA 2R0BA 3V0FA 5KA4A 4S0GA 1D5RA 3O3LA 2BV5A 1LYVA 2CNGA 3M4UA 1Q6MA 4Z6BA 3ZM2A 3AWFA 4RH5A 4Y14A 5KA8A 1LARA 4I8NA 2F6TA 2VEXA 5LXQB 2C46A 5K24A 5K22A 5KA9A 4QAPA 1YGUA 2VEVA 1YZ4A 1WAXA 3O4UA 1ONYA 2HB1A 2A3KA 3F81A 4WOHA 2AHSA 1G4WR 1BZHA 2CMAA 1PXHA 3QCHA 1GFYA 3QCIA 2E0TA 4ZN5A 2OUDA 3EU0A 3I36A 2I5XA 2CNFA 4KI9A 2WGPA 4TVVA 5AWXA 3RGOA 4WU3A 3RO1A 2QDMA 3QKPA 4R0SA 2I6JA 5MMZB 1GWZA 3MOZA 2F46A 4YR8B 2ZN7A 1I57A 2I4HA 1KAKA 1L8GA 1RPMA 2PSZA 4NWFA 1L8KA 2B49A
chains in the Genus database with same CATH superfamily
3V0JA 2F71A 1P15A 2B4SA 1C88A 2RF6A 3D44A 4QF5A 3S3EA 2Y2FA 2WJPA 2H02A 4OHIA 2F6FA 1JBWA 1OESA 2Y68A 2AZRA 3O5XA 2VEYA 3ZM3A 2ZMMA 1KAVA 4QUNA 3S3KA 3EMUA 5GTJA 3EAXA 2GC6A 3EB1A 3NMEA 2H4KA 1Q6NA 1FPZA 2GC5A 2I4GA 3HN7A 5KADA 4ERCA 4MBBA 3RGQA 3I80A 2FJMA 2OOQA 4GFUA 2HC2A 4JBCA 2BIJA 2NTAA 1X24A 2CNEA 3ZM1A 2J17A 2HNQA 2IMGA 2F6WA 3S4OA 5KACA 1C86A 2HCMA 5K25A 4ZIYA 1OHDA 4QDIA 3H2XA 1RXDA 2VORA 1OEVA 1G1GA 2H04A 2JFFA 1ONZA 2VOSA 2Y96A 1XM2A 1YTWA 2HY3A 4NWGA 1AAXA 4HJPA 1C87A 3ZMQA 1OEOX 5K23A 2PI7A 1P3DA 1Q1MA 1ZCLA 2I1YA 4NX8A 3OMHA 1T48A 1QXKA 1JBVA 1YTNA 4D3PA 1PTTA 1GG4A 2CNHA 2JJDA 2Y66A 3QCJA 2CM7A 4HJQA 5KA1A 1T49A 1FPRA 3SR9A 2SHPA 2M3VA 3V0EA 2NT7A 4H34A 3V0HA 5BUGA 2H4GA 3A5KA 3QCBA 2I3RA 2BGDA 2QBQA 1MKPA 1I9TA 1C83A 3LJ8A 4OHEA 4BUCA 2I6IA 4HV4A 1G7FA 2PA5A 1A5YA 3BRHA 2I6OA 4JNBA 1PA9A 1BZCA 3I7ZA 1G7GA 1WCHA 2VEWA 2PQ5A 3U96A 2B3OA 2QBPA 1PYNA 3ZV2A 2B4UA 2I6PA 1O5ZA 1PH0A 4DGPA 3ZM5A 1OHEA 1G1FA 2AM1A 4RI5A 2F00A 1I9SA 2F6YA 4UAGA 1OETA 3B7OA 2FJNA 3D42A 2UUOA 1EENA 1ZC0A 3QCCA 2HVLA 3F9BA 1NWEA 1PTYA 5BZXA 1GQQA 2PT0A 4B04A 5BX1A 3V0IA 2CMBA 4KYRA 2P4DA 1XBOA 3QCMA 2Q05A 4OHDA 3QCNA 4GWFA 4RI4A 4GE6A 1C84A 2QDPA 1PTUA 3BLUA 3CWEA 1ZZWA 2QCTA 1M3GA 3F9AA 3QCGA 2NV5A 4D3QA 1YFOA 3AWGA 4H1OA 4Y2EA 1U25A 4IKCA 1W7KA 2QBSA 4WU2A 2VEUA 3PS5A 2I75A 4GS0A 2CFVA 2H4VA 2QCJA 1OHCA 1XRIA 2HXPA 3UAGA 5M43A 4GE5A 2CM8A 1PA1A 3PYZA 2H03A 2CM3A 4BUBA 1U26A 5I6VA 1QZ0A 4AZ1A 2UUPA 3GXHA 2FH7A 1YTSA 3ZMPA 3A5JA 2B4PA 5K9VA 3BM8A 2WTZA 4QBEA 1P31A 3S3FA 1PTVA 1JF7A 1GQYA 3V0DA 5IBMA 2QDCA 1Q6JA 5KA7A 2NLKA 5KA0A 5IBSA 4WTYA 1E0DA 1JLNA 3D1QA 1Q6PA 3S4EA 2CNIA 5EHRA 2PBNA 4OHLA 4RHGA 1SUGA 4RKKA 3MOWA 2VTEA 2XJAA 3QCEA 1C85A 3RZ2A 1ZCKA 4QUMA 1YGRA 5K9WA 2VTDA 2GCAA 4RH9A 1NNYA 2HC1A 1BZJA 2C7SA 3F99A 3O4TA 5KA3A 5KAAA 4R30A 3AWEA 4GE2A 2B07A 1FQ1A 2I6MA 4ICZA 1NWLA 2CM2A 2GJTA 1ECVA 2Q47A 2DXPA 3V0GA 2NT2A 2G6ZA 3S3HA 3D1HA 3O4SA 2GP0A 3EZZA 1G1HA 5BZZA 4BJOA 5KABA 4CVKA 1XXPA 5J8RA 1Q6TA 1VHRA 4GFVA 4QAHA 4RDDA 2CMCA 4HRFA 4R0TA 3BLTA 2QBRA 4GRYA 2UAGA 2J16A 4ZRTA 4JMJA 2BGEA 1G4US 4C13A 3ZM6A 4PVGA 1EEHA 1XXVA 2G59A 4YAAA 1E8CA 3QCFA 1EEOA 2CJZA 2I42A 2YDUA 2B4OA 2Y1OA 3GXGA 2MBCA 3MMJA 2OZ5A 2QEPA 2J16B 1WRMA 2GWOA 2HNPA 4D3RA 3ZL8A 1U24A 2P6XA 2OC3A 4C12A 4NNDA 2A8BA 3OLRA 1OEMX 1UAGA 1R6HA 4KYQA 4ZI4A 5A5EA 1OEUA 5HDEA 1YN9A 3D1OA 2F6VA 2GCBA 2JFGA 2I4EA 4GRZA 1YPTA 4J51A 2NZ6A 1V3AA 3CM3A 1NL9A 3QCDA 3QCZA 5KA2A 2I3UA 1LQFA 3D9CA 3N0AA 1YWFA 3QCLA 2X5OA 1NZ7A 2JFHA 2BZLA 2F6ZA 4JMKA 4BPCA 1NO6A 3SMEA 1T4JA 3QKQA 1Q6SA 4QBWA 3MVNA 3ZM0A 2F70A 2ESBA 3QCKA 4OHHA 4PYHA 5EHPA 3F41A 4DGXA 1J4XA 1J6UA 4NYHA 2R0BA 3V0FA 5KA4A 4S0GA 1D5RA 3O3LA 2BV5A 1LYVA 2CNGA 3M4UA 1Q6MA 4Z6BA 3ZM2A 3AWFA 4RH5A 4Y14A 5KA8A 1LARA 4CVMA 2Y67A 4I8NA 2F6TA 2VEXA 5LXQB 2C46A 5K24A 3N2AA 5K22A 5KA9A 4QAPA 1YGUA 2VEVA 1YZ4A 1WAXA 3O4UA 1ONYA 2HB1A 2A3KA 2AM2A 3F81A 4WOHA 2AHSA 1G4WR 1BZHA 2CMAA 1PXHA 3QCHA 1GFYA 1W78A 3QCIA 3LK7A 2E0TA 4ZN5A 2OUDA 3EU0A 3I36A 2I5XA 2CNFA 4KI9A 2WGPA 1FGSA 4TVVA 5AWXA 3RGOA 3NRSA 4WU3A 2XPCA 3RO1A 2QDMA 3QKPA 4CVLA 4R0SA 2I6JA 5MMZB 1GWZA 3MOZA 2F46A 4YR8B 2ZN7A 1I57A 2I4HA 5A5FA 1KAKA 1L8GA 1RPMA 2PSZA 4NWFA 1L8KA 2B49A
chains in the Genus database with same CATH topology
3V0JA 2F71A 1P15A 2B4SA 1C88A 2RF6A 3D44A 3S3EA 2Y2FA 2H02A 4OHIA 2F6FA 1OESA 2AZRA 3O5XA 2VEYA 3ZM3A 2ZMMA 1KAVA 4QUNA 3S3KA 3EMUA 5GTJA 3EAXA 3EB1A 3NMEA 2H4KA 1Q6NA 1FPZA 2I4GA 5KADA 4ERCA 4MBBA 3RGQA 3I80A 2FJMA 2OOQA 4GFUA 2HC2A 4JBCA 2BIJA 2NTAA 1X24A 2CNEA 3ZM1A 2J17A 2HNQA 2IMGA 2F6WA 3S4OA 5KACA 1C86A 2HCMA 5K25A 1OHDA 3H2XA 1RXDA 1OEVA 1G1GA 2H04A 1ONZA 2Y96A 1XM2A 1YTWA 2HY3A 4NWGA 1AAXA 4HJPA 1C87A 3ZMQA 1OEOX 5K23A 2PI7A 1Q1MA 1ZCLA 2I1YA 4NX8A 3OMHA 1T48A 1QXKA 1YTNA 4D3PA 1PTTA 2CNHA 2JJDA 5KA1A 3QCJA 2CM7A 4HJQA 1T49A 1FPRA 3SR9A 2SHPA 2M3VA 3V0EA 2NT7A 4H34A 3V0HA 5BUGA 2H4GA 3A5KA 3QCBA 2I3RA 2BGDA 2QBQA 1MKPA 1I9TA 1C83A 3LJ8A 4OHEA 2I6IA 1G7FA 2PA5A 1A5YA 3BRHA 2I6OA 4JNBA 1PA9A 1BZCA 3I7ZA 1G7GA 1WCHA 2VEWA 2PQ5A 3U96A 2B3OA 2QBPA 1PYNA 3ZV2A 2B4UA 2I6PA 1PH0A 4DGPA 1OHEA 1G1FA 4RI5A 1I9SA 2F6YA 1OETA 3B7OA 2FJNA 3D42A 1EENA 1ZC0A 3QCCA 2HVLA 3F9BA 1NWEA 1PTYA 5BZXA 2PT0A 4B04A 5BX1A 3V0IA 2CMBA 4KYRA 2P4DA 1XBOA 3QCMA 2Q05A 4OHDA 3QCNA 4GWFA 4RI4A 4GE6A 1C84A 2QDPA 1PTUA 3BLUA 3CWEA 1ZZWA 2QCTA 1M3GA 3F9AA 3QCGA 2NV5A 4D3QA 1YFOA 3AWGA 4H1OA 4Y2EA 1U25A 4IKCA 2QBSA 4WU2A 3PS5A 2VEUA 2I75A 4GS0A 2CFVA 2H4VA 2QCJA 1OHCA 1XRIA 2HXPA 5M43A 4GE5A 2CM8A 1PA1A 2H03A 2CM3A 1U26A 5I6VA 1QZ0A 4AZ1A 3GXHA 2FH7A 1YTSA 3ZMPA 3A5JA 2B4PA 5K9VA 3BM8A 4QBEA 3S3FA 1JF7A 1PTVA 3V0DA 5IBMA 2QDCA 1Q6JA 5KA7A 2NLKA 5KA0A 5IBSA 4WTYA 1JLNA 3D1QA 1Q6PA 3S4EA 2CNIA 5EHRA 2PBNA 4OHLA 4RHGA 1SUGA 4RKKA 3MOWA 3QCEA 1C85A 3RZ2A 1ZCKA 4QUMA 1YGRA 5K9WA 4RH9A 1NNYA 2HC1A 1BZJA 2C7SA 3F99A 3O4TA 5KA3A 5KAAA 4R30A 3AWEA 4GE2A 2B07A 1FQ1A 2I6MA 4ICZA 1NWLA 2CM2A 2GJTA 1ECVA 2Q47A 2DXPA 3V0GA 2NT2A 2G6ZA 3S3HA 3D1HA 3O4SA 2GP0A 3EZZA 1G1HA 5BZZA 4BJOA 5KABA 1XXPA 5J8RA 1Q6TA 1VHRA 4GFVA 4QAHA 4RDDA 2CMCA 4HRFA 4R0TA 3BLTA 2QBRA 4GRYA 2J16A 4ZRTA 4JMJA 2BGEA 1G4US 4PVGA 4YAAA 1XXVA 2G59A 3QCFA 1EEOA 2CJZA 2I42A 2YDUA 2B4OA 3GXGA 2MBCA 3MMJA 2OZ5A 2QEPA 2J16B 1WRMA 2GWOA 2HNPA 4D3RA 1U24A 2P6XA 2OC3A 4NNDA 2A8BA 3OLRA 1OEMX 1R6HA 4KYQA 4ZI4A 1OEUA 5HDEA 1YN9A 3D1OA 2F6VA 2I4EA 4GRZA 1YPTA 4J51A 2NZ6A 1V3AA 3CM3A 1NL9A 3QCDA 5KA2A 2I3UA 1LQFA 3D9CA 3N0AA 1YWFA 3QCLA 1NZ7A 2BZLA 2F6ZA 4JMKA 4BPCA 1NO6A 3SMEA 1T4JA 3QKQA 1Q6SA 4QBWA 3ZM0A 2F70A 2ESBA 3QCKA 4OHHA 4PYHA 5EHPA 3F41A 4DGXA 1J4XA 4NYHA 2R0BA 3V0FA 5KA4A 4S0GA 1D5RA 3O3LA 2BV5A 1LYVA 2CNGA 3M4UA 1Q6MA 4Z6BA 3ZM2A 3AWFA 4RH5A 4Y14A 5KA8A 1LARA 4I8NA 2F6TA 2VEXA 5LXQB 2C46A 5K24A 5K22A 5KA9A 4QAPA 1YGUA 2VEVA 1YZ4A 1WAXA 3O4UA 1ONYA 2HB1A 2A3KA 3F81A 4WOHA 2AHSA 1G4WR 1BZHA 2CMAA 1PXHA 3QCHA 1GFYA 3QCIA 2E0TA 4ZN5A 2OUDA 3EU0A 3I36A 2I5XA 2CNFA 4KI9A 2WGPA 4TVVA 5AWXA 3RGOA 4WU3A 3RO1A 2QDMA 3QKPA 4R0SA 2I6JA 5MMZB 1GWZA 3MOZA 2F46A 4YR8B 2ZN7A 1I57A 2I4HA 1KAKA 1L8GA 1RPMA 2PSZA 4NWFA 1L8KA 2B49A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V0J A;  2F71 A;  1P15 A;  2B4S A;  1C88 A;  2RF6 A;  3D44 A;  3S3E A;  2Y2F A;  2H02 A;  4OHI A;  2F6F A;  1OES A;  2AZR A;  3O5X A;  2VEY A;  3ZM3 A;  2ZMM A;  1KAV A;  4QUN A;  3S3K A;  3EMU A;  5GTJ A;  3EAX A;  3EB1 A;  3NME A;  2H4K A;  1Q6N A;  1FPZ A;  2I4G A;  5KAD A;  4ERC A;  4MBB A;  3RGQ A;  3I80 A;  2FJM A;  2OOQ A;  4GFU A;  2HC2 A;  4JBC A;  2BIJ A;  2NTA A;  1X24 A;  2CNE A;  3ZM1 A;  2J17 A;  2HNQ A;  2IMG A;  2F6W A;  3S4O A;  5KAC A;  1C86 A;  2HCM A;  5K25 A;  1OHD A;  3H2X A;  1RXD A;  1OEV A;  1G1G A;  2H04 A;  1ONZ A;  2Y96 A;  1XM2 A;  1YTW A;  2HY3 A;  4NWG A;  1AAX A;  4HJP A;  1C87 A;  3ZMQ A;  1OEO X;  5K23 A;  2PI7 A;  1Q1M A;  1ZCL A;  2I1Y A;  4NX8 A;  3OMH A;  1T48 A;  1QXK A;  1YTN A;  4D3P A;  1PTT A;  2CNH A;  2JJD A;  5KA1 A;  3QCJ A;  2CM7 A;  4HJQ A;  1T49 A;  1FPR A;  3SR9 A;  2SHP A;  2M3V A;  3V0E A;  2NT7 A;  4H34 A;  3V0H A;  5BUG A;  2H4G A;  3A5K A;  3QCB A;  2I3R A;  2BGD A;  2QBQ A;  1MKP A;  1I9T A;  1C83 A;  3LJ8 A;  4OHE A;  2I6I A;  1G7F A;  2PA5 A;  1A5Y A;  3BRH A;  2I6O A;  4JNB A;  1PA9 A;  1BZC A;  3I7Z A;  1G7G A;  1WCH A;  2VEW A;  2PQ5 A;  3U96 A;  2B3O A;  2QBP A;  1PYN A;  3ZV2 A;  2B4U A;  2I6P A;  1PH0 A;  4DGP A;  1OHE A;  1G1F A;  4RI5 A;  1I9S A;  2F6Y A;  1OET A;  3B7O A;  2FJN A;  3D42 A;  1EEN A;  1ZC0 A;  3QCC A;  2HVL A;  3F9B A;  1NWE A;  1PTY A;  5BZX A;  2PT0 A;  4B04 A;  5BX1 A;  3V0I A;  2CMB A;  4KYR A;  2P4D A;  1XBO A;  3QCM A;  2Q05 A;  4OHD A;  3QCN A;  4GWF A;  4RI4 A;  4GE6 A;  1C84 A;  2QDP A;  1PTU A;  3BLU A;  3CWE A;  1ZZW A;  2QCT A;  1M3G A;  3F9A A;  3QCG A;  2NV5 A;  4D3Q A;  1YFO A;  3AWG A;  4H1O A;  4Y2E A;  1U25 A;  4IKC A;  2QBS A;  4WU2 A;  3PS5 A;  2VEU A;  2I75 A;  4GS0 A;  2CFV A;  2H4V A;  2QCJ A;  1OHC A;  1XRI A;  2HXP A;  5M43 A;  4GE5 A;  2CM8 A;  1PA1 A;  2H03 A;  2CM3 A;  1U26 A;  5I6V A;  1QZ0 A;  4AZ1 A;  3GXH A;  2FH7 A;  1YTS A;  3ZMP A;  3A5J A;  2B4P A;  5K9V A;  3BM8 A;  4QBE A;  3S3F A;  1JF7 A;  1PTV A;  3V0D A;  5IBM A;  2QDC A;  1Q6J A;  5KA7 A;  2NLK A;  5KA0 A;  5IBS A;  4WTY A;  1JLN A;  3D1Q A;  1Q6P A;  3S4E A;  2CNI A;  5EHR A;  2PBN A;  4OHL A;  4RHG A;  1SUG A;  4RKK A;  3MOW A;  3QCE A;  1C85 A;  3RZ2 A;  1ZCK A;  4QUM A;  1YGR A;  5K9W A;  4RH9 A;  1NNY A;  2HC1 A;  1BZJ A;  2C7S A;  3F99 A;  3O4T A;  5KA3 A;  5KAA A;  4R30 A;  3AWE A;  4GE2 A;  2B07 A;  1FQ1 A;  2I6M A;  4ICZ A;  1NWL A;  2CM2 A;  2GJT A;  1ECV A;  2Q47 A;  2DXP A;  3V0G A;  2NT2 A;  2G6Z A;  3S3H A;  3D1H A;  3O4S A;  2GP0 A;  3EZZ A;  1G1H A;  5BZZ A;  4BJO A;  5KAB A;  1XXP A;  5J8R A;  1Q6T A;  1VHR A;  4GFV A;  4QAH A;  4RDD A;  2CMC A;  4HRF A;  4R0T A;  3BLT A;  2QBR A;  4GRY A;  2J16 A;  4ZRT A;  4JMJ A;  2BGE A;  1G4U S;  4PVG A;  4YAA A;  1XXV A;  2G59 A;  3QCF A;  1EEO A;  2CJZ A;  2I42 A;  2YDU A;  2B4O A;  3GXG A;  2MBC A;  3MMJ A;  2OZ5 A;  2QEP A;  2J16 B;  1WRM A;  2GWO A;  2HNP A;  4D3R A;  1U24 A;  2P6X A;  2OC3 A;  4NND A;  2A8B A;  3OLR A;  1OEM X;  1R6H A;  4KYQ A;  4ZI4 A;  1OEU A;  5HDE A;  1YN9 A;  3D1O A;  2F6V A;  2I4E A;  4GRZ A;  1YPT A;  4J51 A;  2NZ6 A;  1V3A A;  3CM3 A;  1NL9 A;  3QCD A;  5KA2 A;  2I3U A;  1LQF A;  3D9C A;  3N0A A;  1YWF A;  3QCL A;  1NZ7 A;  2BZL A;  2F6Z A;  4JMK A;  4BPC A;  1NO6 A;  3SME A;  1T4J A;  3QKQ A;  1Q6S A;  4QBW A;  3ZM0 A;  2F70 A;  2ESB A;  3QCK A;  4OHH A;  4PYH A;  5EHP A;  3F41 A;  4DGX A;  1J4X A;  4NYH A;  2R0B A;  3V0F A;  5KA4 A;  4S0G A;  1D5R A;  3O3L A;  2BV5 A;  1LYV A;  2CNG A;  3M4U A;  1Q6M A;  4Z6B A;  3ZM2 A;  3AWF A;  4RH5 A;  4Y14 A;  5KA8 A;  1LAR A;  4I8N A;  2F6T A;  2VEX A;  5LXQ B;  2C46 A;  5K24 A;  5K22 A;  5KA9 A;  4QAP A;  1YGU A;  2VEV A;  1YZ4 A;  1WAX A;  3O4U A;  1ONY A;  2HB1 A;  2A3K A;  3F81 A;  4WOH A;  2AHS A;  1G4W R;  1BZH A;  2CMA A;  1PXH A;  3QCH A;  1GFY A;  3QCI A;  2E0T A;  4ZN5 A;  2OUD A;  3EU0 A;  3I36 A;  2I5X A;  2CNF A;  4KI9 A;  2WGP A;  4TVV A;  5AWX A;  3RGO A;  4WU3 A;  3RO1 A;  2QDM A;  3QKP A;  4R0S A;  2I6J A;  5MMZ B;  1GWZ A;  3MOZ A;  2F46 A;  4YR8 B;  2ZN7 A;  1I57 A;  2I4H A;  1KAK A;  1L8G A;  1RPM A;  2PSZ A;  4NWF A;  1L8K A;  2B49 A; 
#chains in the Genus database with same CATH topology
 3V0J A;  2F71 A;  1P15 A;  2B4S A;  1C88 A;  2RF6 A;  3D44 A;  4QF5 A;  3S3E A;  2Y2F A;  2WJP A;  2H02 A;  4OHI A;  2F6F A;  1JBW A;  1OES A;  2Y68 A;  2AZR A;  3O5X A;  2VEY A;  3ZM3 A;  2ZMM A;  1KAV A;  4QUN A;  3S3K A;  3EMU A;  5GTJ A;  3EAX A;  2GC6 A;  3EB1 A;  3NME A;  2H4K A;  1Q6N A;  1FPZ A;  2GC5 A;  2I4G A;  3HN7 A;  5KAD A;  4ERC A;  4MBB A;  3RGQ A;  3I80 A;  2FJM A;  2OOQ A;  4GFU A;  2HC2 A;  4JBC A;  2BIJ A;  2NTA A;  1X24 A;  2CNE A;  3ZM1 A;  2J17 A;  2HNQ A;  2IMG A;  2F6W A;  3S4O A;  5KAC A;  1C86 A;  2HCM A;  5K25 A;  4ZIY A;  1OHD A;  4QDI A;  3H2X A;  1RXD A;  2VOR A;  1OEV A;  1G1G A;  2H04 A;  2JFF A;  1ONZ A;  2VOS A;  2Y96 A;  1XM2 A;  1YTW A;  2HY3 A;  4NWG A;  1AAX A;  4HJP A;  1C87 A;  3ZMQ A;  1OEO X;  5K23 A;  2PI7 A;  1P3D A;  1Q1M A;  1ZCL A;  2I1Y A;  4NX8 A;  3OMH A;  1T48 A;  1QXK A;  1JBV A;  1YTN A;  4D3P A;  1PTT A;  1GG4 A;  2CNH A;  2JJD A;  2Y66 A;  3QCJ A;  2CM7 A;  4HJQ A;  5KA1 A;  1T49 A;  1FPR A;  3SR9 A;  2SHP A;  2M3V A;  3V0E A;  2NT7 A;  4H34 A;  3V0H A;  5BUG A;  2H4G A;  3A5K A;  3QCB A;  2I3R A;  2BGD A;  2QBQ A;  1MKP A;  1I9T A;  1C83 A;  3LJ8 A;  4OHE A;  4BUC A;  2I6I A;  4HV4 A;  1G7F A;  2PA5 A;  1A5Y A;  3BRH A;  2I6O A;  4JNB A;  1PA9 A;  1BZC A;  3I7Z A;  1G7G A;  1WCH A;  2VEW A;  2PQ5 A;  3U96 A;  2B3O A;  2QBP A;  1PYN A;  3ZV2 A;  2B4U A;  2I6P A;  1O5Z A;  1PH0 A;  4DGP A;  3ZM5 A;  1OHE A;  1G1F A;  2AM1 A;  4RI5 A;  2F00 A;  1I9S A;  2F6Y A;  4UAG A;  1OET A;  3B7O A;  2FJN A;  3D42 A;  2UUO A;  1EEN A;  1ZC0 A;  3QCC A;  2HVL A;  3F9B A;  1NWE A;  1PTY A;  5BZX A;  1GQQ A;  2PT0 A;  4B04 A;  5BX1 A;  3V0I A;  2CMB A;  4KYR A;  2P4D A;  1XBO A;  3QCM A;  2Q05 A;  4OHD A;  3QCN A;  4GWF A;  4RI4 A;  4GE6 A;  1C84 A;  2QDP A;  1PTU A;  3BLU A;  3CWE A;  1ZZW A;  2QCT A;  1M3G A;  3F9A A;  3QCG A;  2NV5 A;  4D3Q A;  1YFO A;  3AWG A;  4H1O A;  4Y2E A;  1U25 A;  4IKC A;  1W7K A;  2QBS A;  4WU2 A;  2VEU A;  3PS5 A;  2I75 A;  4GS0 A;  2CFV A;  2H4V A;  2QCJ A;  1OHC A;  1XRI A;  2HXP A;  3UAG A;  5M43 A;  4GE5 A;  2CM8 A;  1PA1 A;  3PYZ A;  2H03 A;  2CM3 A;  4BUB A;  1U26 A;  5I6V A;  1QZ0 A;  4AZ1 A;  2UUP A;  3GXH A;  2FH7 A;  1YTS A;  3ZMP A;  3A5J A;  2B4P A;  5K9V A;  3BM8 A;  2WTZ A;  4QBE A;  1P31 A;  3S3F A;  1PTV A;  1JF7 A;  1GQY A;  3V0D A;  5IBM A;  2QDC A;  1Q6J A;  5KA7 A;  2NLK A;  5KA0 A;  5IBS A;  4WTY A;  1E0D A;  1JLN A;  3D1Q A;  1Q6P A;  3S4E A;  2CNI A;  5EHR A;  2PBN A;  4OHL A;  4RHG A;  1SUG A;  4RKK A;  3MOW A;  2VTE A;  2XJA A;  3QCE A;  1C85 A;  3RZ2 A;  1ZCK A;  4QUM A;  1YGR A;  5K9W A;  2VTD A;  2GCA A;  4RH9 A;  1NNY A;  2HC1 A;  1BZJ A;  2C7S A;  3F99 A;  3O4T A;  5KA3 A;  5KAA A;  4R30 A;  3AWE A;  4GE2 A;  2B07 A;  1FQ1 A;  2I6M A;  4ICZ A;  1NWL A;  2CM2 A;  2GJT A;  1ECV A;  2Q47 A;  2DXP A;  3V0G A;  2NT2 A;  2G6Z A;  3S3H A;  3D1H A;  3O4S A;  2GP0 A;  3EZZ A;  1G1H A;  5BZZ A;  4BJO A;  5KAB A;  4CVK A;  1XXP A;  5J8R A;  1Q6T A;  1VHR A;  4GFV A;  4QAH A;  4RDD A;  2CMC A;  4HRF A;  4R0T A;  3BLT A;  2QBR A;  4GRY A;  2UAG A;  2J16 A;  4ZRT A;  4JMJ A;  2BGE A;  1G4U S;  4C13 A;  3ZM6 A;  4PVG A;  1EEH A;  1XXV A;  2G59 A;  4YAA A;  1E8C A;  3QCF A;  1EEO A;  2CJZ A;  2I42 A;  2YDU A;  2B4O A;  2Y1O A;  3GXG A;  2MBC A;  3MMJ A;  2OZ5 A;  2QEP A;  2J16 B;  1WRM A;  2GWO A;  2HNP A;  4D3R A;  3ZL8 A;  1U24 A;  2P6X A;  2OC3 A;  4C12 A;  4NND A;  2A8B A;  3OLR A;  1OEM X;  1UAG A;  1R6H A;  4KYQ A;  4ZI4 A;  5A5E A;  1OEU A;  5HDE A;  1YN9 A;  3D1O A;  2F6V A;  2GCB A;  2JFG A;  2I4E A;  4GRZ A;  1YPT A;  4J51 A;  2NZ6 A;  1V3A A;  3CM3 A;  1NL9 A;  3QCD A;  3QCZ A;  5KA2 A;  2I3U A;  1LQF A;  3D9C A;  3N0A A;  1YWF A;  3QCL A;  2X5O A;  1NZ7 A;  2JFH A;  2BZL A;  2F6Z A;  4JMK A;  4BPC A;  1NO6 A;  3SME A;  1T4J A;  3QKQ A;  1Q6S A;  4QBW A;  3MVN A;  3ZM0 A;  2F70 A;  2ESB A;  3QCK A;  4OHH A;  4PYH A;  5EHP A;  3F41 A;  4DGX A;  1J4X A;  1J6U A;  4NYH A;  2R0B A;  3V0F A;  5KA4 A;  4S0G A;  1D5R A;  3O3L A;  2BV5 A;  1LYV A;  2CNG A;  3M4U A;  1Q6M A;  4Z6B A;  3ZM2 A;  3AWF A;  4RH5 A;  4Y14 A;  5KA8 A;  1LAR A;  4CVM A;  2Y67 A;  4I8N A;  2F6T A;  2VEX A;  5LXQ B;  2C46 A;  5K24 A;  3N2A A;  5K22 A;  5KA9 A;  4QAP A;  1YGU A;  2VEV A;  1YZ4 A;  1WAX A;  3O4U A;  1ONY A;  2HB1 A;  2A3K A;  2AM2 A;  3F81 A;  4WOH A;  2AHS A;  1G4W R;  1BZH A;  2CMA A;  1PXH A;  3QCH A;  1GFY A;  1W78 A;  3QCI A;  3LK7 A;  2E0T A;  4ZN5 A;  2OUD A;  3EU0 A;  3I36 A;  2I5X A;  2CNF A;  4KI9 A;  2WGP A;  1FGS A;  4TVV A;  5AWX A;  3RGO A;  3NRS A;  4WU3 A;  2XPC A;  3RO1 A;  2QDM A;  3QKP A;  4CVL A;  4R0S A;  2I6J A;  5MMZ B;  1GWZ A;  3MOZ A;  2F46 A;  4YR8 B;  2ZN7 A;  1I57 A;  2I4H A;  5A5F A;  1KAK A;  1L8G A;  1RPM A;  2PSZ A;  4NWF A;  1L8K A;  2B49 A; 
#chains in the Genus database with same CATH homology
 3V0J A;  2F71 A;  1P15 A;  2B4S A;  1C88 A;  2RF6 A;  3D44 A;  3S3E A;  2Y2F A;  2H02 A;  4OHI A;  2F6F A;  1OES A;  2AZR A;  3O5X A;  2VEY A;  3ZM3 A;  2ZMM A;  1KAV A;  4QUN A;  3S3K A;  3EMU A;  5GTJ A;  3EAX A;  3EB1 A;  3NME A;  2H4K A;  1Q6N A;  1FPZ A;  2I4G A;  5KAD A;  4ERC A;  4MBB A;  3RGQ A;  3I80 A;  2FJM A;  2OOQ A;  4GFU A;  2HC2 A;  4JBC A;  2BIJ A;  2NTA A;  1X24 A;  2CNE A;  3ZM1 A;  2J17 A;  2HNQ A;  2IMG A;  2F6W A;  3S4O A;  5KAC A;  1C86 A;  2HCM A;  5K25 A;  1OHD A;  3H2X A;  1RXD A;  1OEV A;  1G1G A;  2H04 A;  1ONZ A;  2Y96 A;  1XM2 A;  1YTW A;  2HY3 A;  4NWG A;  1AAX A;  4HJP A;  1C87 A;  3ZMQ A;  1OEO X;  5K23 A;  2PI7 A;  1Q1M A;  1ZCL A;  2I1Y A;  4NX8 A;  3OMH A;  1T48 A;  1QXK A;  1YTN A;  4D3P A;  1PTT A;  2CNH A;  2JJD A;  5KA1 A;  3QCJ A;  2CM7 A;  4HJQ A;  1T49 A;  1FPR A;  3SR9 A;  2SHP A;  2M3V A;  3V0E A;  2NT7 A;  4H34 A;  3V0H A;  5BUG A;  2H4G A;  3A5K A;  3QCB A;  2I3R A;  2BGD A;  2QBQ A;  1MKP A;  1I9T A;  1C83 A;  3LJ8 A;  4OHE A;  2I6I A;  1G7F A;  2PA5 A;  1A5Y A;  3BRH A;  2I6O A;  4JNB A;  1PA9 A;  1BZC A;  3I7Z A;  1G7G A;  1WCH A;  2VEW A;  2PQ5 A;  3U96 A;  2B3O A;  2QBP A;  1PYN A;  3ZV2 A;  2B4U A;  2I6P A;  1PH0 A;  4DGP A;  1OHE A;  1G1F A;  4RI5 A;  1I9S A;  2F6Y A;  1OET A;  3B7O A;  2FJN A;  3D42 A;  1EEN A;  1ZC0 A;  3QCC A;  2HVL A;  3F9B A;  1NWE A;  1PTY A;  5BZX A;  2PT0 A;  4B04 A;  5BX1 A;  3V0I A;  2CMB A;  4KYR A;  2P4D A;  1XBO A;  3QCM A;  2Q05 A;  4OHD A;  3QCN A;  4GWF A;  4RI4 A;  4GE6 A;  1C84 A;  2QDP A;  1PTU A;  3BLU A;  3CWE A;  1ZZW A;  2QCT A;  1M3G A;  3F9A A;  3QCG A;  2NV5 A;  4D3Q A;  1YFO A;  3AWG A;  4H1O A;  4Y2E A;  1U25 A;  4IKC A;  2QBS A;  4WU2 A;  3PS5 A;  2VEU A;  2I75 A;  4GS0 A;  2CFV A;  2H4V A;  2QCJ A;  1OHC A;  1XRI A;  2HXP A;  5M43 A;  4GE5 A;  2CM8 A;  1PA1 A;  2H03 A;  2CM3 A;  1U26 A;  5I6V A;  1QZ0 A;  4AZ1 A;  3GXH A;  2FH7 A;  1YTS A;  3ZMP A;  3A5J A;  2B4P A;  5K9V A;  3BM8 A;  4QBE A;  3S3F A;  1JF7 A;  1PTV A;  3V0D A;  5IBM A;  2QDC A;  1Q6J A;  5KA7 A;  2NLK A;  5KA0 A;  5IBS A;  4WTY A;  1JLN A;  3D1Q A;  1Q6P A;  3S4E A;  2CNI A;  5EHR A;  2PBN A;  4OHL A;  4RHG A;  1SUG A;  4RKK A;  3MOW A;  3QCE A;  1C85 A;  3RZ2 A;  1ZCK A;  4QUM A;  1YGR A;  5K9W A;  4RH9 A;  1NNY A;  2HC1 A;  1BZJ A;  2C7S A;  3F99 A;  3O4T A;  5KA3 A;  5KAA A;  4R30 A;  3AWE A;  4GE2 A;  2B07 A;  1FQ1 A;  2I6M A;  4ICZ A;  1NWL A;  2CM2 A;  2GJT A;  1ECV A;  2Q47 A;  2DXP A;  3V0G A;  2NT2 A;  2G6Z A;  3S3H A;  3D1H A;  3O4S A;  2GP0 A;  3EZZ A;  1G1H A;  5BZZ A;  4BJO A;  5KAB A;  1XXP A;  5J8R A;  1Q6T A;  1VHR A;  4GFV A;  4QAH A;  4RDD A;  2CMC A;  4HRF A;  4R0T A;  3BLT A;  2QBR A;  4GRY A;  2J16 A;  4ZRT A;  4JMJ A;  2BGE A;  1G4U S;  4PVG A;  4YAA A;  1XXV A;  2G59 A;  3QCF A;  1EEO A;  2CJZ A;  2I42 A;  2YDU A;  2B4O A;  3GXG A;  2MBC A;  3MMJ A;  2OZ5 A;  2QEP A;  2J16 B;  1WRM A;  2GWO A;  2HNP A;  4D3R A;  1U24 A;  2P6X A;  2OC3 A;  4NND A;  2A8B A;  3OLR A;  1OEM X;  1R6H A;  4KYQ A;  4ZI4 A;  1OEU A;  5HDE A;  1YN9 A;  3D1O A;  2F6V A;  2I4E A;  4GRZ A;  1YPT A;  4J51 A;  2NZ6 A;  1V3A A;  3CM3 A;  1NL9 A;  3QCD A;  5KA2 A;  2I3U A;  1LQF A;  3D9C A;  3N0A A;  1YWF A;  3QCL A;  1NZ7 A;  2BZL A;  2F6Z A;  4JMK A;  4BPC A;  1NO6 A;  3SME A;  1T4J A;  3QKQ A;  1Q6S A;  4QBW A;  3ZM0 A;  2F70 A;  2ESB A;  3QCK A;  4OHH A;  4PYH A;  5EHP A;  3F41 A;  4DGX A;  1J4X A;  4NYH A;  2R0B A;  3V0F A;  5KA4 A;  4S0G A;  1D5R A;  3O3L A;  2BV5 A;  1LYV A;  2CNG A;  3M4U A;  1Q6M A;  4Z6B A;  3ZM2 A;  3AWF A;  4RH5 A;  4Y14 A;  5KA8 A;  1LAR A;  4I8N A;  2F6T A;  2VEX A;  5LXQ B;  2C46 A;  5K24 A;  5K22 A;  5KA9 A;  4QAP A;  1YGU A;  2VEV A;  1YZ4 A;  1WAX A;  3O4U A;  1ONY A;  2HB1 A;  2A3K A;  3F81 A;  4WOH A;  2AHS A;  1G4W R;  1BZH A;  2CMA A;  1PXH A;  3QCH A;  1GFY A;  3QCI A;  2E0T A;  4ZN5 A;  2OUD A;  3EU0 A;  3I36 A;  2I5X A;  2CNF A;  4KI9 A;  2WGP A;  4TVV A;  5AWX A;  3RGO A;  4WU3 A;  3RO1 A;  2QDM A;  3QKP A;  4R0S A;  2I6J A;  5MMZ B;  1GWZ A;  3MOZ A;  2F46 A;  4YR8 B;  2ZN7 A;  1I57 A;  2I4H A;  1KAK A;  1L8G A;  1RPM A;  2PSZ A;  4NWF A;  1L8K A;  2B49 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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