2NTA | Genus

Total Genus 106

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	106
sequence length	297
structure length	297
Chain Sequence	EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Probing acid replacements of thiophene PTP1B inhibitors. pubmed doi rcsb
molecule keywords	Tyrosine-protein phosphatase non-receptor type 1
total genus	106
structure length	297
sequence length	297
ec nomenclature	ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date	2006-11-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00102	Y_phosphatase	Protein-tyrosine phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.190.10	Alpha Beta	Alpha-Beta Complex	Protein-Tyrosine Phosphatase; Chain A	Protein tyrosine phosphatase superfamily	2ntaA00

2A3KA 1U25A 2BGDA 3QCNA 2PI7A 1NZ7A 5KA8A 4S0GA 5KADA 2F6TA 1AAXA 1Q6MA 1Q6PA 2JJDA 2CMCA 3O4UA 1LYVA 1NL9A 3RGQA 1YPTA 1XBOA 3D1HA 1ZCLA 3MOWA 1LARA 2CM7A 2H4GA 4NWGA 5HDEA 2B4UA 4QUMA 2I4EA 2AZRA 2NT2A 3RO1A 1ZC0A 3N0AA 1Q6SA 4BJOA 2E0TA 3F41A 1U26A 4OHEA 2CM2A 1P15A 1GWZA 2BZLA 2CNGA 3EAXA 3SMEA 4OHHA 4R0TA 3ZMPA 5KABA 5KAAA 1C84A 2HCMA 1XM2A 4RHGA 4R30A 2YDUA 3QCFA 3CWEA 2F6ZA 1Q6NA 1KAKA 1BZJA 5KA7A 3S3FA 4JBCA 2I75A 2B4OA 2B4PA 3O3LA 4H34A 2I3RA 2VEVA 3EU0A 3EMUA 4BPCA 1C88A 3AWGA 3RZ2A 1G4WR 4KI9A 2H4KA 4I8NA 1KAVA 2CMAA 3V0IA 4NNDA 1ZZWA 4ERCA 2ESBA 1OETA 5K25A 2I6PA 2F71A 1M3GA 2I1YA 3F99A 4ZI4A 3MOZA 4GE5A 2CMBA 1YFOA 1T48A 2FJMA 3EZZA 4RI4A 3A5KA 2H4VA 3QCDA 2FH7A 2F6VA 3V0EA 3S3KA 2G6ZA 3ZMQA 1OEOX 2I6MA 4B04A 4MBBA 1OEUA 3QCLA 4WTYA 5AWXA 2DXPA 2OUDA 5BX1A 3V0HA 1OESA 1OEMX 1PTUA 1V3AA 2OOQA 5KA0A 3S4EA 1WAXA 1ECVA 4DGPA 1U24A 2HXPA 1L8KA 1OHEA 4HJQA 4RDDA 3QCKA 3QCGA 1C87A 1PA9A 3M4UA 1R6HA 2HNQA 4GE6A 2Q05A 4GFUA 5EHPA 2NZ6A 4ZN5A 3GXGA 4TVVA 1I57A 1XRIA 3D1QA 1NWEA 2VEUA 2VEYA 1Q1MA 2B07A 5KA9A 2BIJA 1LQFA 4WU3A 3S3EA 2MBCA 3I80A 3I7ZA 3O5XA 2PQ5A 3QCIA 5EHRA 1C86A 1YTWA 3O4SA 5GTJA 2QDCA 2ZN7A 3AWFA 1YZ4A 3D44A 2AHSA 2CNFA 1OEVA 2I6JA 3QCCA 3H2XA 3QCHA 1RPMA 2I4HA 4PYHA 3ZM3A 2QBQA 1ZCKA 1Q6JA 2M3VA 2IMGA 4J51A 4HRFA 4AZ1A 1WRMA 2CNIA 4JMKA 3S3HA 4HJPA 4H1OA 4OHIA 2VEWA 3QCBA 2SHPA 2NTAA 1QZ0A 1BZCA 2WGPA 2B49A 3U96A 3V0FA 2ZMMA 3MMJA 5MMZB 5I6VA 2J17A 1PXHA 4D3PA 2C7SA 2QDPA 3BLTA 2HNPA 4QUNA 1G1FA 1QXKA 1EENA 1YGRA 4Y2EA 4QAPA 1OHCA 5M43A 2QCTA 4RH9A 3QKPA 4Z6BA 3B7OA 2Y96A 2J16A 4GS0A 2RF6A 1RXDA 2GWOA 2PBNA 1FPRA 2CFVA 5IBSA 2F6YA 1VHRA 1I9SA 5KA3A 1G7FA 4RI5A 1PTTA 3SR9A 2OC3A 4D3QA 1A5YA 1Q6TA 1ONYA 2CNEA 2H03A 2J16B 3CM3A 4YAAA 1X24A 5J8RA 1FQ1A 4WOHA 2QEPA 1XXVA 4IKCA 1C85A 3ZM2A 1PH0A 3EB1A 2NLKA 4GWFA 1PTVA 2I6IA 1YTNA 4PVGA 5LXQB 4KYQA 1YTSA 1YWFA 4NYHA 2I6OA 4DGXA 4ICZA 3D1OA 2F6WA 4QBEA 4R0SA 1BZHA 1D5RA 2QCJA 2B3OA 1EEOA 4NX8A 5KACA 4GRYA 2A8BA 1OHDA 1NO6A 1NNYA 3PS5A 2H04A 3BRHA 2I3UA 1G7GA 2F70A 5KA2A 2I5XA 3AWEA 3GXHA 3F81A 1FPZA 3QCEA 5K23A 2HVLA 4ZRTA 2F46A 2I42A 2QDMA 3LJ8A 4QAHA 1T49A 2Q47A 4QBWA 2F6FA 3V0JA 5K9WA 2H02A 3V0DA 3OLRA 1GFYA 5K24A 4JNBA 2VEXA 1T4JA 2PA5A 4NWFA 1C83A 2C46A 2R0BA 1NWLA 2I4GA 5BZXA 1L8GA 3F9AA 2HC2A 2CNHA 2HC1A 2P6XA 3D9CA 5K9VA 2P4DA 2G59A 5IBMA 2QBSA 4D3RA 2QBPA 3QKQA 2QBRA 3O4TA 5BZZA 1PTYA 2GP0A 4RKKA 2PSZA 3ZM0A 1XXPA 4OHLA 2CM3A 4RH5A 3RGOA 1G1HA 3ZM1A 2OZ5A 5KA1A 1ONZA 2PT0A 1SUGA 1WCHA 3V0GA 1JLNA 3BLUA 1PA1A 2Y2FA 3D42A 4YR8B 4WU2A 3NMEA 1JF7A 1G1GA 5K22A 1MKPA 1YN9A 2BGEA 2CM8A 2B4SA 1YGUA 3QCJA 5BUGA 1J4XA 3F9BA 3ZV2A 4GRZA 3OMHA 4KYRA 2NT7A 4Y14A 2HY3A 3S4OA 2NV5A 1PYNA 1I9TA 3BM8A 4GFVA 2FJNA 5KA4A 4JMJA 4GE2A 2HB1A 2GJTA 4OHDA 3QCMA 3I36A 2CJZA 3A5JA 2BV5A 1G4US
chains in the Genus database with same CATH superfamily

2A3KA 2UUPA 1U25A 2BGDA 3QCNA 4UAGA 2PI7A 1NZ7A 5KA8A 4S0GA 5KADA 2F6TA 1AAXA 1Q6MA 2Y67A 1Q6PA 2JJDA 2CMCA 3O4UA 1LYVA 1NL9A 3RGQA 1YPTA 1XBOA 2VTDA 1ZCLA 3D1HA 3MOWA 1LARA 2CM7A 2H4GA 4NWGA 5HDEA 2B4UA 4QUMA 2I4EA 2AZRA 2AM2A 2NT2A 3RO1A 1ZC0A 1EEHA 3N0AA 1GG4A 1Q6SA 4BJOA 2E0TA 3F41A 1U26A 4OHEA 2CM2A 1P15A 1GWZA 2BZLA 2CNGA 3EAXA 3SMEA 4OHHA 4R0TA 3ZMPA 5KABA 5KAAA 1C84A 2HCMA 1XM2A 1FGSA 2XPCA 4RHGA 1O5ZA 2YDUA 4R30A 3QCFA 2JFHA 3CWEA 2F6ZA 1Q6NA 1KAKA 1BZJA 5KA7A 3S3FA 4JBCA 2I75A 2B4OA 2B4PA 3O3LA 4H34A 1W78A 2I3RA 3ZL8A 2VEVA 4BUBA 4CVLA 3EU0A 3EMUA 4BPCA 1C88A 3AWGA 3RZ2A 1G4WR 4KI9A 2H4KA 4I8NA 1KAVA 2CMAA 3V0IA 3UAGA 4NNDA 1ZZWA 4ERCA 2ESBA 1JBWA 1OETA 5K25A 2I6PA 2F71A 1M3GA 2UUOA 2I1YA 3F99A 4ZI4A 3MOZA 2GC5A 4GE5A 1E0DA 2CMBA 1YFOA 1T48A 2FJMA 3EZZA 4RI4A 3A5KA 2H4VA 3QCDA 2FH7A 2F6VA 3V0EA 3S3KA 1E8CA 2G6ZA 3ZMQA 1OEOX 3MVNA 4BUCA 1P31A 2I6MA 4B04A 4MBBA 1OEUA 3QCLA 4WTYA 5AWXA 2DXPA 2OUDA 1J6UA 5BX1A 3V0HA 1OESA 1OEMX 1PTUA 1V3AA 2OOQA 2VORA 5KA0A 3S4EA 1WAXA 1ECVA 3N2AA 4DGPA 1U24A 2HXPA 1L8KA 1OHEA 4HJQA 4RDDA 3QCKA 3QCGA 1C87A 1PA9A 3M4UA 1R6HA 2F00A 2HNQA 4GE6A 2Q05A 4GFUA 5EHPA 2NZ6A 4ZN5A 2VOSA 3GXGA 4TVVA 1I57A 1XRIA 3D1QA 1NWEA 2JFGA 2VEUA 2VEYA 1Q1MA 2B07A 3PYZA 5KA9A 2BIJA 1LQFA 4WU3A 3S3EA 2MBCA 3I80A 2Y66A 3I7ZA 3O5XA 2PQ5A 3QCIA 5EHRA 1C86A 3ZM6A 1YTWA 3O4SA 5GTJA 2QDCA 2ZN7A 3AWFA 1YZ4A 3D44A 2AHSA 2CNFA 1OEVA 2I6JA 3QCCA 3H2XA 3QCHA 1RPMA 2I4HA 4PYHA 3ZM3A 2QBQA 1ZCKA 1Q6JA 2M3VA 2IMGA 4J51A 4HRFA 4AZ1A 1WRMA 5A5EA 2CNIA 4JMKA 3S3HA 2X5OA 1UAGA 4HJPA 2JFFA 4H1OA 4OHIA 2VEWA 3QCBA 2SHPA 2NTAA 1QZ0A 1BZCA 2WGPA 2B49A 3U96A 3V0FA 2ZMMA 3MMJA 5MMZB 5I6VA 2J17A 1PXHA 4D3PA 4CVKA 2C7SA 2QDPA 3BLTA 2HNPA 4QUNA 1G1FA 1QXKA 1EENA 1YGRA 4Y2EA 4QAPA 1OHCA 5M43A 2QCTA 4RH9A 3QKPA 1W7KA 4Z6BA 3B7OA 2Y96A 2J16A 4GS0A 2RF6A 1P3DA 1RXDA 2GWOA 2PBNA 1FPRA 2CFVA 2Y1OA 5IBSA 2F6YA 2GCBA 1VHRA 3ZM5A 1I9SA 5KA3A 1G7FA 4RI5A 1PTTA 3SR9A 2OC3A 2WJPA 2WTZA 4D3QA 1A5YA 1Q6TA 1ONYA 2CNEA 2H03A 3LK7A 2J16B 2GCAA 3CM3A 4YAAA 1X24A 5J8RA 1FQ1A 4WOHA 2QEPA 1XXVA 3HN7A 4IKCA 1C85A 3ZM2A 1PH0A 3EB1A 2NLKA 4GWFA 1PTVA 2I6IA 1YTNA 4PVGA 5LXQB 4KYQA 1YTSA 1YWFA 4NYHA 2I6OA 4QDIA 4DGXA 4ICZA 3D1OA 2UAGA 2F6WA 4QBEA 1GQQA 4R0SA 1BZHA 1D5RA 2QCJA 2B3OA 1EEOA 4NX8A 5KACA 4GRYA 2A8BA 1OHDA 1NO6A 1NNYA 3PS5A 2H04A 3BRHA 2I3UA 1G7GA 2F70A 5KA2A 2I5XA 3AWEA 3GXHA 3F81A 1FPZA 3QCEA 5K23A 2HVLA 4ZRTA 2F46A 2I42A 2QDMA 3LJ8A 4QAHA 1T49A 2GC6A 2Q47A 5A5FA 2Y68A 4QBWA 2F6FA 3V0JA 5K9WA 2H02A 3V0DA 3OLRA 4HV4A 1GFYA 5K24A 4JNBA 4QF5A 2VEXA 1T4JA 2PA5A 4NWFA 1C83A 2C46A 2R0BA 1NWLA 2I4GA 5BZXA 1L8GA 3F9AA 2HC2A 2CNHA 2HC1A 2P6XA 3D9CA 5K9VA 2P4DA 2G59A 2XJAA 5IBMA 2QBSA 4D3RA 2QBPA 3QKQA 2QBRA 3O4TA 5BZZA 1GQYA 1PTYA 2GP0A 4RKKA 2PSZA 3ZM0A 1XXPA 4OHLA 2CM3A 4RH5A 3RGOA 1G1HA 3ZM1A 2OZ5A 5KA1A 2AM1A 1ONZA 2PT0A 1SUGA 1WCHA 3V0GA 1JLNA 2VTEA 3NRSA 3BLUA 1PA1A 2Y2FA 3D42A 4YR8B 4WU2A 3NMEA 4C12A 1JF7A 1G1GA 5K22A 1MKPA 1YN9A 4C13A 1JBVA 2BGEA 2CM8A 2B4SA 1YGUA 3QCJA 5BUGA 1J4XA 3F9BA 3ZV2A 4GRZA 3OMHA 4KYRA 2NT7A 4Y14A 2HY3A 3S4OA 2NV5A 1PYNA 1I9TA 3BM8A 4GFVA 2FJNA 5KA4A 3QCZA 4CVMA 4JMJA 4GE2A 2HB1A 2GJTA 4OHDA 4ZIYA 3QCMA 3I36A 2CJZA 3A5JA 2BV5A 1G4US
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2A3K A;  1U25 A;  2BGD A;  3QCN A;  2PI7 A;  1NZ7 A;  5KA8 A;  4S0G A;  5KAD A;  2F6T A;  1AAX A;  1Q6M A;  1Q6P A;  2JJD A;  2CMC A;  3O4U A;  1LYV A;  1NL9 A;  3RGQ A;  1YPT A;  1XBO A;  3D1H A;  1ZCL A;  3MOW A;  1LAR A;  2CM7 A;  2H4G A;  4NWG A;  5HDE A;  2B4U A;  4QUM A;  2I4E A;  2AZR A;  2NT2 A;  3RO1 A;  1ZC0 A;  3N0A A;  1Q6S A;  4BJO A;  2E0T A;  3F41 A;  1U26 A;  4OHE A;  2CM2 A;  1P15 A;  1GWZ A;  2BZL A;  2CNG A;  3EAX A;  3SME A;  4OHH A;  4R0T A;  3ZMP A;  5KAB A;  5KAA A;  1C84 A;  2HCM A;  1XM2 A;  4RHG A;  4R30 A;  2YDU A;  3QCF A;  3CWE A;  2F6Z A;  1Q6N A;  1KAK A;  1BZJ A;  5KA7 A;  3S3F A;  4JBC A;  2I75 A;  2B4O A;  2B4P A;  3O3L A;  4H34 A;  2I3R A;  2VEV A;  3EU0 A;  3EMU A;  4BPC A;  1C88 A;  3AWG A;  3RZ2 A;  1G4W R;  4KI9 A;  2H4K A;  4I8N A;  1KAV A;  2CMA A;  3V0I A;  4NND A;  1ZZW A;  4ERC A;  2ESB A;  1OET A;  5K25 A;  2I6P A;  2F71 A;  1M3G A;  2I1Y A;  3F99 A;  4ZI4 A;  3MOZ A;  4GE5 A;  2CMB A;  1YFO A;  1T48 A;  2FJM A;  3EZZ A;  4RI4 A;  3A5K A;  2H4V A;  3QCD A;  2FH7 A;  2F6V A;  3V0E A;  3S3K A;  2G6Z A;  3ZMQ A;  1OEO X;  2I6M A;  4B04 A;  4MBB A;  1OEU A;  3QCL A;  4WTY A;  5AWX A;  2DXP A;  2OUD A;  5BX1 A;  3V0H A;  1OES A;  1OEM X;  1PTU A;  1V3A A;  2OOQ A;  5KA0 A;  3S4E A;  1WAX A;  1ECV A;  4DGP A;  1U24 A;  2HXP A;  1L8K A;  1OHE A;  4HJQ A;  4RDD A;  3QCK A;  3QCG A;  1C87 A;  1PA9 A;  3M4U A;  1R6H A;  2HNQ A;  4GE6 A;  2Q05 A;  4GFU A;  5EHP A;  2NZ6 A;  4ZN5 A;  3GXG A;  4TVV A;  1I57 A;  1XRI A;  3D1Q A;  1NWE A;  2VEU A;  2VEY A;  1Q1M A;  2B07 A;  5KA9 A;  2BIJ A;  1LQF A;  4WU3 A;  3S3E A;  2MBC A;  3I80 A;  3I7Z A;  3O5X A;  2PQ5 A;  3QCI A;  5EHR A;  1C86 A;  1YTW A;  3O4S A;  5GTJ A;  2QDC A;  2ZN7 A;  3AWF A;  1YZ4 A;  3D44 A;  2AHS A;  2CNF A;  1OEV A;  2I6J A;  3QCC A;  3H2X A;  3QCH A;  1RPM A;  2I4H A;  4PYH A;  3ZM3 A;  2QBQ A;  1ZCK A;  1Q6J A;  2M3V A;  2IMG A;  4J51 A;  4HRF A;  4AZ1 A;  1WRM A;  2CNI A;  4JMK A;  3S3H A;  4HJP A;  4H1O A;  4OHI A;  2VEW A;  3QCB A;  2SHP A;  2NTA A;  1QZ0 A;  1BZC A;  2WGP A;  2B49 A;  3U96 A;  3V0F A;  2ZMM A;  3MMJ A;  5MMZ B;  5I6V A;  2J17 A;  1PXH A;  4D3P A;  2C7S A;  2QDP A;  3BLT A;  2HNP A;  4QUN A;  1G1F A;  1QXK A;  1EEN A;  1YGR A;  4Y2E A;  4QAP A;  1OHC A;  5M43 A;  2QCT A;  4RH9 A;  3QKP A;  4Z6B A;  3B7O A;  2Y96 A;  2J16 A;  4GS0 A;  2RF6 A;  1RXD A;  2GWO A;  2PBN A;  1FPR A;  2CFV A;  5IBS A;  2F6Y A;  1VHR A;  1I9S A;  5KA3 A;  1G7F A;  4RI5 A;  1PTT A;  3SR9 A;  2OC3 A;  4D3Q A;  1A5Y A;  1Q6T A;  1ONY A;  2CNE A;  2H03 A;  2J16 B;  3CM3 A;  4YAA A;  1X24 A;  5J8R A;  1FQ1 A;  4WOH A;  2QEP A;  1XXV A;  4IKC A;  1C85 A;  3ZM2 A;  1PH0 A;  3EB1 A;  2NLK A;  4GWF A;  1PTV A;  2I6I A;  1YTN A;  4PVG A;  5LXQ B;  4KYQ A;  1YTS A;  1YWF A;  4NYH A;  2I6O A;  4DGX A;  4ICZ A;  3D1O A;  2F6W A;  4QBE A;  4R0S A;  1BZH A;  1D5R A;  2QCJ A;  2B3O A;  1EEO A;  4NX8 A;  5KAC A;  4GRY A;  2A8B A;  1OHD A;  1NO6 A;  1NNY A;  3PS5 A;  2H04 A;  3BRH A;  2I3U A;  1G7G A;  2F70 A;  5KA2 A;  2I5X A;  3AWE A;  3GXH A;  3F81 A;  1FPZ A;  3QCE A;  5K23 A;  2HVL A;  4ZRT A;  2F46 A;  2I42 A;  2QDM A;  3LJ8 A;  4QAH A;  1T49 A;  2Q47 A;  4QBW A;  2F6F A;  3V0J A;  5K9W A;  2H02 A;  3V0D A;  3OLR A;  1GFY A;  5K24 A;  4JNB A;  2VEX A;  1T4J A;  2PA5 A;  4NWF A;  1C83 A;  2C46 A;  2R0B A;  1NWL A;  2I4G A;  5BZX A;  1L8G A;  3F9A A;  2HC2 A;  2CNH A;  2HC1 A;  2P6X A;  3D9C A;  5K9V A;  2P4D A;  2G59 A;  5IBM A;  2QBS A;  4D3R A;  2QBP A;  3QKQ A;  2QBR A;  3O4T A;  5BZZ A;  1PTY A;  2GP0 A;  4RKK A;  2PSZ A;  3ZM0 A;  1XXP A;  4OHL A;  2CM3 A;  4RH5 A;  3RGO A;  1G1H A;  3ZM1 A;  2OZ5 A;  5KA1 A;  1ONZ A;  2PT0 A;  1SUG A;  1WCH A;  3V0G A;  1JLN A;  3BLU A;  1PA1 A;  2Y2F A;  3D42 A;  4YR8 B;  4WU2 A;  3NME A;  1JF7 A;  1G1G A;  5K22 A;  1MKP A;  1YN9 A;  2BGE A;  2CM8 A;  2B4S A;  1YGU A;  3QCJ A;  5BUG A;  1J4X A;  3F9B A;  3ZV2 A;  4GRZ A;  3OMH A;  4KYR A;  2NT7 A;  4Y14 A;  2HY3 A;  3S4O A;  2NV5 A;  1PYN A;  1I9T A;  3BM8 A;  4GFV A;  2FJN A;  5KA4 A;  4JMJ A;  4GE2 A;  2HB1 A;  2GJT A;  4OHD A;  3QCM A;  3I36 A;  2CJZ A;  3A5J A;  2BV5 A;  1G4U S; 
#chains in the Genus database with same CATH topology
 2A3K A;  2UUP A;  1U25 A;  2BGD A;  3QCN A;  4UAG A;  2PI7 A;  1NZ7 A;  5KA8 A;  4S0G A;  5KAD A;  2F6T A;  1AAX A;  1Q6M A;  2Y67 A;  1Q6P A;  2JJD A;  2CMC A;  3O4U A;  1LYV A;  1NL9 A;  3RGQ A;  1YPT A;  1XBO A;  2VTD A;  1ZCL A;  3D1H A;  3MOW A;  1LAR A;  2CM7 A;  2H4G A;  4NWG A;  5HDE A;  2B4U A;  4QUM A;  2I4E A;  2AZR A;  2AM2 A;  2NT2 A;  3RO1 A;  1ZC0 A;  1EEH A;  3N0A A;  1GG4 A;  1Q6S A;  4BJO A;  2E0T A;  3F41 A;  1U26 A;  4OHE A;  2CM2 A;  1P15 A;  1GWZ A;  2BZL A;  2CNG A;  3EAX A;  3SME A;  4OHH A;  4R0T A;  3ZMP A;  5KAB A;  5KAA A;  1C84 A;  2HCM A;  1XM2 A;  1FGS A;  2XPC A;  4RHG A;  1O5Z A;  2YDU A;  4R30 A;  3QCF A;  2JFH A;  3CWE A;  2F6Z A;  1Q6N A;  1KAK A;  1BZJ A;  5KA7 A;  3S3F A;  4JBC A;  2I75 A;  2B4O A;  2B4P A;  3O3L A;  4H34 A;  1W78 A;  2I3R A;  3ZL8 A;  2VEV A;  4BUB A;  4CVL A;  3EU0 A;  3EMU A;  4BPC A;  1C88 A;  3AWG A;  3RZ2 A;  1G4W R;  4KI9 A;  2H4K A;  4I8N A;  1KAV A;  2CMA A;  3V0I A;  3UAG A;  4NND A;  1ZZW A;  4ERC A;  2ESB A;  1JBW A;  1OET A;  5K25 A;  2I6P A;  2F71 A;  1M3G A;  2UUO A;  2I1Y A;  3F99 A;  4ZI4 A;  3MOZ A;  2GC5 A;  4GE5 A;  1E0D A;  2CMB A;  1YFO A;  1T48 A;  2FJM A;  3EZZ A;  4RI4 A;  3A5K A;  2H4V A;  3QCD A;  2FH7 A;  2F6V A;  3V0E A;  3S3K A;  1E8C A;  2G6Z A;  3ZMQ A;  1OEO X;  3MVN A;  4BUC A;  1P31 A;  2I6M A;  4B04 A;  4MBB A;  1OEU A;  3QCL A;  4WTY A;  5AWX A;  2DXP A;  2OUD A;  1J6U A;  5BX1 A;  3V0H A;  1OES A;  1OEM X;  1PTU A;  1V3A A;  2OOQ A;  2VOR A;  5KA0 A;  3S4E A;  1WAX A;  1ECV A;  3N2A A;  4DGP A;  1U24 A;  2HXP A;  1L8K A;  1OHE A;  4HJQ A;  4RDD A;  3QCK A;  3QCG A;  1C87 A;  1PA9 A;  3M4U A;  1R6H A;  2F00 A;  2HNQ A;  4GE6 A;  2Q05 A;  4GFU A;  5EHP A;  2NZ6 A;  4ZN5 A;  2VOS A;  3GXG A;  4TVV A;  1I57 A;  1XRI A;  3D1Q A;  1NWE A;  2JFG A;  2VEU A;  2VEY A;  1Q1M A;  2B07 A;  3PYZ A;  5KA9 A;  2BIJ A;  1LQF A;  4WU3 A;  3S3E A;  2MBC A;  3I80 A;  2Y66 A;  3I7Z A;  3O5X A;  2PQ5 A;  3QCI A;  5EHR A;  1C86 A;  3ZM6 A;  1YTW A;  3O4S A;  5GTJ A;  2QDC A;  2ZN7 A;  3AWF A;  1YZ4 A;  3D44 A;  2AHS A;  2CNF A;  1OEV A;  2I6J A;  3QCC A;  3H2X A;  3QCH A;  1RPM A;  2I4H A;  4PYH A;  3ZM3 A;  2QBQ A;  1ZCK A;  1Q6J A;  2M3V A;  2IMG A;  4J51 A;  4HRF A;  4AZ1 A;  1WRM A;  5A5E A;  2CNI A;  4JMK A;  3S3H A;  2X5O A;  1UAG A;  4HJP A;  2JFF A;  4H1O A;  4OHI A;  2VEW A;  3QCB A;  2SHP A;  2NTA A;  1QZ0 A;  1BZC A;  2WGP A;  2B49 A;  3U96 A;  3V0F A;  2ZMM A;  3MMJ A;  5MMZ B;  5I6V A;  2J17 A;  1PXH A;  4D3P A;  4CVK A;  2C7S A;  2QDP A;  3BLT A;  2HNP A;  4QUN A;  1G1F A;  1QXK A;  1EEN A;  1YGR A;  4Y2E A;  4QAP A;  1OHC A;  5M43 A;  2QCT A;  4RH9 A;  3QKP A;  1W7K A;  4Z6B A;  3B7O A;  2Y96 A;  2J16 A;  4GS0 A;  2RF6 A;  1P3D A;  1RXD A;  2GWO A;  2PBN A;  1FPR A;  2CFV A;  2Y1O A;  5IBS A;  2F6Y A;  2GCB A;  1VHR A;  3ZM5 A;  1I9S A;  5KA3 A;  1G7F A;  4RI5 A;  1PTT A;  3SR9 A;  2OC3 A;  2WJP A;  2WTZ A;  4D3Q A;  1A5Y A;  1Q6T A;  1ONY A;  2CNE A;  2H03 A;  3LK7 A;  2J16 B;  2GCA A;  3CM3 A;  4YAA A;  1X24 A;  5J8R A;  1FQ1 A;  4WOH A;  2QEP A;  1XXV A;  3HN7 A;  4IKC A;  1C85 A;  3ZM2 A;  1PH0 A;  3EB1 A;  2NLK A;  4GWF A;  1PTV A;  2I6I A;  1YTN A;  4PVG A;  5LXQ B;  4KYQ A;  1YTS A;  1YWF A;  4NYH A;  2I6O A;  4QDI A;  4DGX A;  4ICZ A;  3D1O A;  2UAG A;  2F6W A;  4QBE A;  1GQQ A;  4R0S A;  1BZH A;  1D5R A;  2QCJ A;  2B3O A;  1EEO A;  4NX8 A;  5KAC A;  4GRY A;  2A8B A;  1OHD A;  1NO6 A;  1NNY A;  3PS5 A;  2H04 A;  3BRH A;  2I3U A;  1G7G A;  2F70 A;  5KA2 A;  2I5X A;  3AWE A;  3GXH A;  3F81 A;  1FPZ A;  3QCE A;  5K23 A;  2HVL A;  4ZRT A;  2F46 A;  2I42 A;  2QDM A;  3LJ8 A;  4QAH A;  1T49 A;  2GC6 A;  2Q47 A;  5A5F A;  2Y68 A;  4QBW A;  2F6F A;  3V0J A;  5K9W A;  2H02 A;  3V0D A;  3OLR A;  4HV4 A;  1GFY A;  5K24 A;  4JNB A;  4QF5 A;  2VEX A;  1T4J A;  2PA5 A;  4NWF A;  1C83 A;  2C46 A;  2R0B A;  1NWL A;  2I4G A;  5BZX A;  1L8G A;  3F9A A;  2HC2 A;  2CNH A;  2HC1 A;  2P6X A;  3D9C A;  5K9V A;  2P4D A;  2G59 A;  2XJA A;  5IBM A;  2QBS A;  4D3R A;  2QBP A;  3QKQ A;  2QBR A;  3O4T A;  5BZZ A;  1GQY A;  1PTY A;  2GP0 A;  4RKK A;  2PSZ A;  3ZM0 A;  1XXP A;  4OHL A;  2CM3 A;  4RH5 A;  3RGO A;  1G1H A;  3ZM1 A;  2OZ5 A;  5KA1 A;  2AM1 A;  1ONZ A;  2PT0 A;  1SUG A;  1WCH A;  3V0G A;  1JLN A;  2VTE A;  3NRS A;  3BLU A;  1PA1 A;  2Y2F A;  3D42 A;  4YR8 B;  4WU2 A;  3NME A;  4C12 A;  1JF7 A;  1G1G A;  5K22 A;  1MKP A;  1YN9 A;  4C13 A;  1JBV A;  2BGE A;  2CM8 A;  2B4S A;  1YGU A;  3QCJ A;  5BUG A;  1J4X A;  3F9B A;  3ZV2 A;  4GRZ A;  3OMH A;  4KYR A;  2NT7 A;  4Y14 A;  2HY3 A;  3S4O A;  2NV5 A;  1PYN A;  1I9T A;  3BM8 A;  4GFV A;  2FJN A;  5KA4 A;  3QCZ A;  4CVM A;  4JMJ A;  4GE2 A;  2HB1 A;  2GJT A;  4OHD A;  4ZIY A;  3QCM A;  3I36 A;  2CJZ A;  3A5J A;  2BV5 A;  1G4U S; 
#chains in the Genus database with same CATH homology
 2A3K A;  1U25 A;  2BGD A;  3QCN A;  2PI7 A;  1NZ7 A;  5KA8 A;  4S0G A;  5KAD A;  2F6T A;  1AAX A;  1Q6M A;  1Q6P A;  2JJD A;  2CMC A;  3O4U A;  1LYV A;  1NL9 A;  3RGQ A;  1YPT A;  1XBO A;  3D1H A;  1ZCL A;  3MOW A;  1LAR A;  2CM7 A;  2H4G A;  4NWG A;  5HDE A;  2B4U A;  4QUM A;  2I4E A;  2AZR A;  2NT2 A;  3RO1 A;  1ZC0 A;  3N0A A;  1Q6S A;  4BJO A;  2E0T A;  3F41 A;  1U26 A;  4OHE A;  2CM2 A;  1P15 A;  1GWZ A;  2BZL A;  2CNG A;  3EAX A;  3SME A;  4OHH A;  4R0T A;  3ZMP A;  5KAB A;  5KAA A;  1C84 A;  2HCM A;  1XM2 A;  4RHG A;  4R30 A;  2YDU A;  3QCF A;  3CWE A;  2F6Z A;  1Q6N A;  1KAK A;  1BZJ A;  5KA7 A;  3S3F A;  4JBC A;  2I75 A;  2B4O A;  2B4P A;  3O3L A;  4H34 A;  2I3R A;  2VEV A;  3EU0 A;  3EMU A;  4BPC A;  1C88 A;  3AWG A;  3RZ2 A;  1G4W R;  4KI9 A;  2H4K A;  4I8N A;  1KAV A;  2CMA A;  3V0I A;  4NND A;  1ZZW A;  4ERC A;  2ESB A;  1OET A;  5K25 A;  2I6P A;  2F71 A;  1M3G A;  2I1Y A;  3F99 A;  4ZI4 A;  3MOZ A;  4GE5 A;  2CMB A;  1YFO A;  1T48 A;  2FJM A;  3EZZ A;  4RI4 A;  3A5K A;  2H4V A;  3QCD A;  2FH7 A;  2F6V A;  3V0E A;  3S3K A;  2G6Z A;  3ZMQ A;  1OEO X;  2I6M A;  4B04 A;  4MBB A;  1OEU A;  3QCL A;  4WTY A;  5AWX A;  2DXP A;  2OUD A;  5BX1 A;  3V0H A;  1OES A;  1OEM X;  1PTU A;  1V3A A;  2OOQ A;  5KA0 A;  3S4E A;  1WAX A;  1ECV A;  4DGP A;  1U24 A;  2HXP A;  1L8K A;  1OHE A;  4HJQ A;  4RDD A;  3QCK A;  3QCG A;  1C87 A;  1PA9 A;  3M4U A;  1R6H A;  2HNQ A;  4GE6 A;  2Q05 A;  4GFU A;  5EHP A;  2NZ6 A;  4ZN5 A;  3GXG A;  4TVV A;  1I57 A;  1XRI A;  3D1Q A;  1NWE A;  2VEU A;  2VEY A;  1Q1M A;  2B07 A;  5KA9 A;  2BIJ A;  1LQF A;  4WU3 A;  3S3E A;  2MBC A;  3I80 A;  3I7Z A;  3O5X A;  2PQ5 A;  3QCI A;  5EHR A;  1C86 A;  1YTW A;  3O4S A;  5GTJ A;  2QDC A;  2ZN7 A;  3AWF A;  1YZ4 A;  3D44 A;  2AHS A;  2CNF A;  1OEV A;  2I6J A;  3QCC A;  3H2X A;  3QCH A;  1RPM A;  2I4H A;  4PYH A;  3ZM3 A;  2QBQ A;  1ZCK A;  1Q6J A;  2M3V A;  2IMG A;  4J51 A;  4HRF A;  4AZ1 A;  1WRM A;  2CNI A;  4JMK A;  3S3H A;  4HJP A;  4H1O A;  4OHI A;  2VEW A;  3QCB A;  2SHP A;  2NTA A;  1QZ0 A;  1BZC A;  2WGP A;  2B49 A;  3U96 A;  3V0F A;  2ZMM A;  3MMJ A;  5MMZ B;  5I6V A;  2J17 A;  1PXH A;  4D3P A;  2C7S A;  2QDP A;  3BLT A;  2HNP A;  4QUN A;  1G1F A;  1QXK A;  1EEN A;  1YGR A;  4Y2E A;  4QAP A;  1OHC A;  5M43 A;  2QCT A;  4RH9 A;  3QKP A;  4Z6B A;  3B7O A;  2Y96 A;  2J16 A;  4GS0 A;  2RF6 A;  1RXD A;  2GWO A;  2PBN A;  1FPR A;  2CFV A;  5IBS A;  2F6Y A;  1VHR A;  1I9S A;  5KA3 A;  1G7F A;  4RI5 A;  1PTT A;  3SR9 A;  2OC3 A;  4D3Q A;  1A5Y A;  1Q6T A;  1ONY A;  2CNE A;  2H03 A;  2J16 B;  3CM3 A;  4YAA A;  1X24 A;  5J8R A;  1FQ1 A;  4WOH A;  2QEP A;  1XXV A;  4IKC A;  1C85 A;  3ZM2 A;  1PH0 A;  3EB1 A;  2NLK A;  4GWF A;  1PTV A;  2I6I A;  1YTN A;  4PVG A;  5LXQ B;  4KYQ A;  1YTS A;  1YWF A;  4NYH A;  2I6O A;  4DGX A;  4ICZ A;  3D1O A;  2F6W A;  4QBE A;  4R0S A;  1BZH A;  1D5R A;  2QCJ A;  2B3O A;  1EEO A;  4NX8 A;  5KAC A;  4GRY A;  2A8B A;  1OHD A;  1NO6 A;  1NNY A;  3PS5 A;  2H04 A;  3BRH A;  2I3U A;  1G7G A;  2F70 A;  5KA2 A;  2I5X A;  3AWE A;  3GXH A;  3F81 A;  1FPZ A;  3QCE A;  5K23 A;  2HVL A;  4ZRT A;  2F46 A;  2I42 A;  2QDM A;  3LJ8 A;  4QAH A;  1T49 A;  2Q47 A;  4QBW A;  2F6F A;  3V0J A;  5K9W A;  2H02 A;  3V0D A;  3OLR A;  1GFY A;  5K24 A;  4JNB A;  2VEX A;  1T4J A;  2PA5 A;  4NWF A;  1C83 A;  2C46 A;  2R0B A;  1NWL A;  2I4G A;  5BZX A;  1L8G A;  3F9A A;  2HC2 A;  2CNH A;  2HC1 A;  2P6X A;  3D9C A;  5K9V A;  2P4D A;  2G59 A;  5IBM A;  2QBS A;  4D3R A;  2QBP A;  3QKQ A;  2QBR A;  3O4T A;  5BZZ A;  1PTY A;  2GP0 A;  4RKK A;  2PSZ A;  3ZM0 A;  1XXP A;  4OHL A;  2CM3 A;  4RH5 A;  3RGO A;  1G1H A;  3ZM1 A;  2OZ5 A;  5KA1 A;  1ONZ A;  2PT0 A;  1SUG A;  1WCH A;  3V0G A;  1JLN A;  3BLU A;  1PA1 A;  2Y2F A;  3D42 A;  4YR8 B;  4WU2 A;  3NME A;  1JF7 A;  1G1G A;  5K22 A;  1MKP A;  1YN9 A;  2BGE A;  2CM8 A;  2B4S A;  1YGU A;  3QCJ A;  5BUG A;  1J4X A;  3F9B A;  3ZV2 A;  4GRZ A;  3OMH A;  4KYR A;  2NT7 A;  4Y14 A;  2HY3 A;  3S4O A;  2NV5 A;  1PYN A;  1I9T A;  3BM8 A;  4GFV A;  2FJN A;  5KA4 A;  4JMJ A;  4GE2 A;  2HB1 A;  2GJT A;  4OHD A;  3QCM A;  3I36 A;  2CJZ A;  3A5J A;  2BV5 A;  1G4U S;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2NTAA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations