2ZN7 | Genus

Total Genus 106

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	106
sequence length	297
structure length	297
Chain Sequence	EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24 pubmed doi rcsb
molecule keywords	Tyrosine-protein phosphatase non-receptor type 1
total genus	106
structure length	297
sequence length	297
ec nomenclature	ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date	2008-04-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00102	Y_phosphatase	Protein-tyrosine phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.190.10	Alpha Beta	Alpha-Beta Complex	Protein-Tyrosine Phosphatase; Chain A	Protein tyrosine phosphatase superfamily	2zn7A00

3AWGA 2QEPA 2B07A 2HNQA 2FH7A 1OHCA 3F9AA 1T4JA 2QBPA 1RXDA 4RI4A 1T48A 4GE5A 2HCMA 3PS5A 1FPRA 3D44A 3GXGA 4ERCA 1YGUA 2P6XA 1G1HA 3OMHA 1YTSA 2Q05A 3MMJA 4QBWA 4I8NA 2NT2A 2CM8A 2VEVA 2BZLA 4YAAA 5K23A 2I75A 1BZCA 4HRFA 1I9TA 1PTTA 4GE2A 2BGEA 5KACA 2HXPA 2VEYA 1OETA 3O4TA 1VHRA 3D42A 4R30A 2QCTA 4WTYA 2GP0A 4OHIA 1XXVA 1EEOA 2B3OA 2HB1A 2H03A 2VEUA 5K22A 3O4UA 3N0AA 2WGPA 1JLNA 2B4SA 2PQ5A 1OEOX 4ZI4A 2H4KA 1I57A 4B04A 2RF6A 4NWGA 1PXHA 1XRIA 2IMGA 2BV5A 1U25A 5KA0A 5KA2A 2CMBA 2QBSA 3ZMPA 1QXKA 5KA3A 2A3KA 3QCEA 1ZCKA 4KI9A 2F46A 5KA9A 2HNPA 5KADA 2OC3A 4DGPA 3QCJA 2I5XA 2Y2FA 2NTAA 1OESA 2ZN7A 3RZ2A 3V0EA 3CM3A 4RI5A 1LQFA 2CNHA 2CMAA 3V0FA 2C46A 3QCDA 1G4US 4QUMA 1GFYA 1ONZA 1C84A 4WU3A 4JBCA 3S3EA 3U96A 2CNFA 3EAXA 2CM7A 1OHEA 2DXPA 2QBRA 3EU0A 2R0BA 1KAVA 2I6OA 3RGOA 1T49A 2QDMA 4NX8A 1BZHA 5K24A 3ZMQA 3I7ZA 3QKPA 2ESBA 3ZM2A 4JMKA 1L8GA 3BRHA 1JF7A 4Y14A 4S0GA 2CNEA 1ONYA 1NWEA 4H34A 3ZV2A 1FQ1A 4BPCA 1Q6PA 2PT0A 1XBOA 2Y96A 4Z6BA 4D3QA 1YFOA 1Q6MA 3V0HA 1XM2A 2BGDA 1LARA 5IBSA 1L8KA 1LYVA 1Q6NA 4NWFA 2HVLA 1MKPA 2F6YA 2I42A 5EHRA 3EZZA 2C7SA 3NMEA 1NL9A 2F6TA 1PA9A 4RH9A 4PYHA 4WOHA 5KA7A 2I4EA 1V3AA 5J8RA 3D1HA 1ZCLA 1FPZA 1BZJA 1R6HA 3F41A 4PVGA 1NO6A 5IBMA 4OHLA 3M4UA 2F70A 2Q47A 1PYNA 4OHDA 4GFVA 3MOWA 5BX1A 4GRZA 4ICZA 4NNDA 1WAXA 1YTWA 1G7FA 2F6FA 4JMJA 3S3HA 5LXQB 2QCJA 1U26A 2FJNA 3V0DA 1PTUA 3D1QA 5KABA 3QKQA 3V0JA 5M43A 4ZRTA 1G1GA 5BZXA 1J4XA 2HC1A 4RDDA 1RPMA 2P4DA 3F9BA 2CJZA 2H04A 2E0TA 2SHPA 4OHEA 1X24A 3S3FA 2VEWA 2B4UA 4QAHA 4R0TA 3D9CA 3QCNA 2H4GA 5KA8A 2I6IA 2NZ6A 1OHDA 4GE6A 2J16B 2QDPA 3O3LA 2NLKA 5BZZA 2B4OA 5K9WA 2CMCA 1PA1A 2GWOA 3D1OA 1OEVA 2F71A 4YR8B 5I6VA 1QZ0A 3BM8A 4QUNA 4RKKA 2NV5A 3A5JA 4DGXA 1A5YA 1GWZA 3O5XA 2J17A 1PH0A 1I9SA 3S3KA 4MBBA 3F81A 2I3RA 4HJPA 1YZ4A 2F6VA 4NYHA 2AHSA 2F6ZA 3ZM3A 4Y2EA 1G7GA 1Q6SA 1C87A 2PI7A 4RHGA 2J16A 2ZMMA 3B7OA 2B4PA 4KYRA 3EMUA 1YTNA 1ECVA 2HY3A 2I3UA 3V0GA 2BIJA 2OUDA 1AAXA 4GS0A 4AZ1A 3MOZA 1G4WR 2FJMA 3OLRA 4D3PA 3BLUA 5BUGA 2G59A 1PTVA 1D5RA 2B49A 3RO1A 1EENA 5K25A 3QCCA 4KYQA 3A5KA 3QCKA 4BJOA 3QCFA 3BLTA 2CM3A 4GFUA 5MMZB 1WRMA 4TVVA 5EHPA 3I80A 5HDEA 2OZ5A 1NWLA 4QAPA 5KA4A 3S4OA 1OEUA 2GJTA 3EB1A 2CNIA 4IKCA 3F99A 1SUGA 4RH5A 2PSZA 2JJDA 2HC2A 3QCGA 1YN9A 2VEXA 3O4SA 3ZM0A 3CWEA 4D3RA 1C85A 3AWEA 4ZN5A 1C86A 4R0SA 1YGRA 2QDCA 3SR9A 3AWFA 1OEMX 4OHHA 5KAAA 1YWFA 1WCHA 3SMEA 4GWFA 3S4EA 5K9VA 1C83A 3I36A 1KAKA 1C88A 1Q6TA 3V0IA 2QBQA 2I6PA 2I6JA 2PA5A 2CM2A 1NNYA 3QCMA 2AZRA 3GXHA 3RGQA 3QCLA 2F6WA 3QCHA 3QCBA 2A8BA 3H2XA 4HJQA 1P15A 3LJ8A 4WU2A 1NZ7A 2CFVA 1Q1MA 4GRYA 4H1OA 2H4VA 2PBNA 3ZM1A 2CNGA 3QCIA 2G6ZA 5KA1A 5AWXA 4JNBA 4QBEA 2H02A 1G1FA 1YPTA 2M3VA 2I4HA 1ZZWA 2MBCA 2I1YA 2I4GA 2NT7A 1ZC0A 1M3GA 1PTYA 4J51A 5GTJA 1U24A 2YDUA 1Q6JA 2I6MA 2OOQA 1XXPA
chains in the Genus database with same CATH superfamily

3AWGA 1GQQA 4ZIYA 2QEPA 3LK7A 2B07A 2HNQA 2FH7A 1OHCA 3F9AA 1T4JA 2QBPA 1RXDA 4RI4A 1T48A 4GE5A 2HCMA 3PS5A 2Y66A 1FPRA 3D44A 3GXGA 4ERCA 1YGUA 2P6XA 1G1HA 3OMHA 1YTSA 2Q05A 3MMJA 4QBWA 4I8NA 2NT2A 2CM8A 2VEVA 2BZLA 4YAAA 5K23A 2I75A 1BZCA 4HRFA 1I9TA 1PTTA 4GE2A 2BGEA 5KACA 2HXPA 2VEYA 1OETA 3O4TA 1VHRA 3D42A 4R30A 2QCTA 4WTYA 2GP0A 4OHIA 2GCAA 1XXVA 1EEOA 2B3OA 2HB1A 2H03A 2VEUA 5K22A 3O4UA 2GC6A 1E8CA 3N0AA 2WGPA 1JLNA 2B4SA 2PQ5A 1OEOX 4ZI4A 2H4KA 1I57A 4B04A 2RF6A 4NWGA 1PXHA 1XRIA 2IMGA 2BV5A 1U25A 4QDIA 5KA0A 5KA2A 2WTZA 2CMBA 2QBSA 3ZMPA 1QXKA 4BUCA 2A3KA 3QCEA 5KA3A 1ZCKA 4KI9A 2F46A 5KA9A 2HNPA 5KADA 2OC3A 4UAGA 4DGPA 3QCJA 2I5XA 2Y2FA 2NTAA 1OESA 2ZN7A 3RZ2A 3V0EA 3CM3A 4RI5A 1LQFA 2CNHA 2CMAA 2Y1OA 3V0FA 1O5ZA 2C46A 3QCDA 1G4US 4QUMA 1GFYA 4CVMA 1ONZA 1C84A 4WU3A 4JBCA 3S3EA 3U96A 2CNFA 3EAXA 2CM7A 1OHEA 2DXPA 2QBRA 3EU0A 2R0BA 1KAVA 2I6OA 3RGOA 1T49A 2QDMA 4NX8A 1BZHA 5K24A 3MVNA 3ZMQA 3I7ZA 3QKPA 2ESBA 2X5OA 3ZM2A 1W78A 4JMKA 1L8GA 3BRHA 1FGSA 1JF7A 4Y14A 4S0GA 2CNEA 3HN7A 1ONYA 1NWEA 4H34A 3ZV2A 1FQ1A 4BPCA 1Q6PA 2PT0A 1XBOA 2Y96A 4Z6BA 4D3QA 1EEHA 1YFOA 1Q6MA 3V0HA 1XM2A 2BGDA 1LARA 2VTEA 5IBSA 1L8KA 3NRSA 1LYVA 1Q6NA 4NWFA 2HVLA 1MKPA 2F6YA 2UAGA 3PYZA 2I42A 5EHRA 3EZZA 2C7SA 3NMEA 1NL9A 2F6TA 1PA9A 4RH9A 4PYHA 4WOHA 5KA7A 2I4EA 1V3AA 5J8RA 3D1HA 1ZCLA 1FPZA 1BZJA 1R6HA 3F41A 4PVGA 1NO6A 5IBMA 3ZM5A 4OHLA 4HV4A 1JBWA 3M4UA 2F70A 2AM2A 2Q47A 1PYNA 4OHDA 4GFVA 3MOWA 5BX1A 4GRZA 4ICZA 4NNDA 1WAXA 2JFGA 1P3DA 1YTWA 1G7FA 2F6FA 2Y68A 4JMJA 3S3HA 5LXQB 1GQYA 2QCJA 2UUOA 1U26A 2FJNA 3V0DA 1PTUA 3D1QA 5KABA 3QKQA 2VORA 3V0JA 5A5FA 5M43A 4ZRTA 1G1GA 1JBVA 5BZXA 1J4XA 2HC1A 4RDDA 1RPMA 2P4DA 3F9BA 2CJZA 2H04A 2E0TA 2SHPA 4OHEA 1X24A 3S3FA 2VEWA 2B4UA 4QAHA 4R0TA 3D9CA 3QCNA 2H4GA 5A5EA 5KA8A 2I6IA 2JFFA 2F00A 2NZ6A 1OHDA 4GE6A 2J16B 2QDPA 3O3LA 2NLKA 5BZZA 1GG4A 2B4OA 5K9WA 2CMCA 1PA1A 3QCZA 2GWOA 4C12A 3D1OA 1OEVA 2F71A 4YR8B 5I6VA 2UUPA 1P31A 1QZ0A 3BM8A 4QUNA 1E0DA 4RKKA 2NV5A 3A5JA 4DGXA 3ZM6A 1A5YA 1GWZA 3O5XA 2J17A 1PH0A 1I9SA 2XPCA 3S3KA 4MBBA 2WJPA 3F81A 4BUBA 2I3RA 4HJPA 1YZ4A 2F6VA 4NYHA 2Y67A 2AHSA 2F6ZA 3ZM3A 4Y2EA 1G7GA 1Q6SA 1C87A 2PI7A 4RHGA 2J16A 2ZMMA 3B7OA 2B4PA 4KYRA 3EMUA 1YTNA 3ZL8A 1ECVA 2HY3A 2I3UA 3V0GA 2BIJA 2OUDA 1AAXA 4CVLA 4GS0A 4AZ1A 3MOZA 1G4WR 2FJMA 3OLRA 4D3PA 3BLUA 5BUGA 2G59A 1PTVA 1D5RA 2B49A 3RO1A 1EENA 5K25A 3QCCA 4KYQA 2AM1A 3A5KA 3QCKA 4BJOA 3QCFA 3BLTA 1J6UA 2CM3A 4GFUA 5MMZB 1WRMA 4TVVA 2VTDA 5EHPA 3I80A 5HDEA 2OZ5A 1NWLA 4QAPA 5KA4A 3S4OA 1OEUA 2GC5A 2GJTA 3EB1A 2CNIA 4IKCA 3F99A 1SUGA 4RH5A 4CVKA 2PSZA 2JJDA 2HC2A 3QCGA 1YN9A 2VEXA 3O4SA 3ZM0A 3CWEA 4D3RA 1C85A 3AWEA 4ZN5A 1C86A 4R0SA 1YGRA 2QDCA 3SR9A 3AWFA 1OEMX 4OHHA 3UAGA 5KAAA 1YWFA 1WCHA 3SMEA 4GWFA 3S4EA 5K9VA 1C83A 3I36A 1KAKA 1C88A 1Q6TA 2XJAA 3V0IA 2QBQA 2I6PA 2I6JA 2PA5A 2CM2A 1NNYA 3QCMA 4C13A 1W7KA 2AZRA 3GXHA 3RGQA 3QCLA 2F6WA 3QCHA 3QCBA 2A8BA 2GCBA 3H2XA 1P15A 4HJQA 1UAGA 3LJ8A 4WU2A 1NZ7A 2CFVA 1Q1MA 4QF5A 4GRYA 4H1OA 2H4VA 2PBNA 3ZM1A 2CNGA 3QCIA 2G6ZA 3N2AA 5KA1A 5AWXA 4JNBA 4QBEA 2H02A 1G1FA 1YPTA 2M3VA 2JFHA 2I4HA 1ZZWA 2MBCA 2I1YA 2I4GA 2NT7A 1ZC0A 1M3GA 1PTYA 4J51A 5GTJA 1U24A 2YDUA 1Q6JA 2I6MA 2OOQA 2VOSA 1XXPA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3AWG A;  2QEP A;  2B07 A;  2HNQ A;  2FH7 A;  1OHC A;  3F9A A;  1T4J A;  2QBP A;  1RXD A;  4RI4 A;  1T48 A;  4GE5 A;  2HCM A;  3PS5 A;  1FPR A;  3D44 A;  3GXG A;  4ERC A;  1YGU A;  2P6X A;  1G1H A;  3OMH A;  1YTS A;  2Q05 A;  3MMJ A;  4QBW A;  4I8N A;  2NT2 A;  2CM8 A;  2VEV A;  2BZL A;  4YAA A;  5K23 A;  2I75 A;  1BZC A;  4HRF A;  1I9T A;  1PTT A;  4GE2 A;  2BGE A;  5KAC A;  2HXP A;  2VEY A;  1OET A;  3O4T A;  1VHR A;  3D42 A;  4R30 A;  2QCT A;  4WTY A;  2GP0 A;  4OHI A;  1XXV A;  1EEO A;  2B3O A;  2HB1 A;  2H03 A;  2VEU A;  5K22 A;  3O4U A;  3N0A A;  2WGP A;  1JLN A;  2B4S A;  2PQ5 A;  1OEO X;  4ZI4 A;  2H4K A;  1I57 A;  4B04 A;  2RF6 A;  4NWG A;  1PXH A;  1XRI A;  2IMG A;  2BV5 A;  1U25 A;  5KA0 A;  5KA2 A;  2CMB A;  2QBS A;  3ZMP A;  1QXK A;  5KA3 A;  2A3K A;  3QCE A;  1ZCK A;  4KI9 A;  2F46 A;  5KA9 A;  2HNP A;  5KAD A;  2OC3 A;  4DGP A;  3QCJ A;  2I5X A;  2Y2F A;  2NTA A;  1OES A;  2ZN7 A;  3RZ2 A;  3V0E A;  3CM3 A;  4RI5 A;  1LQF A;  2CNH A;  2CMA A;  3V0F A;  2C46 A;  3QCD A;  1G4U S;  4QUM A;  1GFY A;  1ONZ A;  1C84 A;  4WU3 A;  4JBC A;  3S3E A;  3U96 A;  2CNF A;  3EAX A;  2CM7 A;  1OHE A;  2DXP A;  2QBR A;  3EU0 A;  2R0B A;  1KAV A;  2I6O A;  3RGO A;  1T49 A;  2QDM A;  4NX8 A;  1BZH A;  5K24 A;  3ZMQ A;  3I7Z A;  3QKP A;  2ESB A;  3ZM2 A;  4JMK A;  1L8G A;  3BRH A;  1JF7 A;  4Y14 A;  4S0G A;  2CNE A;  1ONY A;  1NWE A;  4H34 A;  3ZV2 A;  1FQ1 A;  4BPC A;  1Q6P A;  2PT0 A;  1XBO A;  2Y96 A;  4Z6B A;  4D3Q A;  1YFO A;  1Q6M A;  3V0H A;  1XM2 A;  2BGD A;  1LAR A;  5IBS A;  1L8K A;  1LYV A;  1Q6N A;  4NWF A;  2HVL A;  1MKP A;  2F6Y A;  2I42 A;  5EHR A;  3EZZ A;  2C7S A;  3NME A;  1NL9 A;  2F6T A;  1PA9 A;  4RH9 A;  4PYH A;  4WOH A;  5KA7 A;  2I4E A;  1V3A A;  5J8R A;  3D1H A;  1ZCL A;  1FPZ A;  1BZJ A;  1R6H A;  3F41 A;  4PVG A;  1NO6 A;  5IBM A;  4OHL A;  3M4U A;  2F70 A;  2Q47 A;  1PYN A;  4OHD A;  4GFV A;  3MOW A;  5BX1 A;  4GRZ A;  4ICZ A;  4NND A;  1WAX A;  1YTW A;  1G7F A;  2F6F A;  4JMJ A;  3S3H A;  5LXQ B;  2QCJ A;  1U26 A;  2FJN A;  3V0D A;  1PTU A;  3D1Q A;  5KAB A;  3QKQ A;  3V0J A;  5M43 A;  4ZRT A;  1G1G A;  5BZX A;  1J4X A;  2HC1 A;  4RDD A;  1RPM A;  2P4D A;  3F9B A;  2CJZ A;  2H04 A;  2E0T A;  2SHP A;  4OHE A;  1X24 A;  3S3F A;  2VEW A;  2B4U A;  4QAH A;  4R0T A;  3D9C A;  3QCN A;  2H4G A;  5KA8 A;  2I6I A;  2NZ6 A;  1OHD A;  4GE6 A;  2J16 B;  2QDP A;  3O3L A;  2NLK A;  5BZZ A;  2B4O A;  5K9W A;  2CMC A;  1PA1 A;  2GWO A;  3D1O A;  1OEV A;  2F71 A;  4YR8 B;  5I6V A;  1QZ0 A;  3BM8 A;  4QUN A;  4RKK A;  2NV5 A;  3A5J A;  4DGX A;  1A5Y A;  1GWZ A;  3O5X A;  2J17 A;  1PH0 A;  1I9S A;  3S3K A;  4MBB A;  3F81 A;  2I3R A;  4HJP A;  1YZ4 A;  2F6V A;  4NYH A;  2AHS A;  2F6Z A;  3ZM3 A;  4Y2E A;  1G7G A;  1Q6S A;  1C87 A;  2PI7 A;  4RHG A;  2J16 A;  2ZMM A;  3B7O A;  2B4P A;  4KYR A;  3EMU A;  1YTN A;  1ECV A;  2HY3 A;  2I3U A;  3V0G A;  2BIJ A;  2OUD A;  1AAX A;  4GS0 A;  4AZ1 A;  3MOZ A;  1G4W R;  2FJM A;  3OLR A;  4D3P A;  3BLU A;  5BUG A;  2G59 A;  1PTV A;  1D5R A;  2B49 A;  3RO1 A;  1EEN A;  5K25 A;  3QCC A;  4KYQ A;  3A5K A;  3QCK A;  4BJO A;  3QCF A;  3BLT A;  2CM3 A;  4GFU A;  5MMZ B;  1WRM A;  4TVV A;  5EHP A;  3I80 A;  5HDE A;  2OZ5 A;  1NWL A;  4QAP A;  5KA4 A;  3S4O A;  1OEU A;  2GJT A;  3EB1 A;  2CNI A;  4IKC A;  3F99 A;  1SUG A;  4RH5 A;  2PSZ A;  2JJD A;  2HC2 A;  3QCG A;  1YN9 A;  2VEX A;  3O4S A;  3ZM0 A;  3CWE A;  4D3R A;  1C85 A;  3AWE A;  4ZN5 A;  1C86 A;  4R0S A;  1YGR A;  2QDC A;  3SR9 A;  3AWF A;  1OEM X;  4OHH A;  5KAA A;  1YWF A;  1WCH A;  3SME A;  4GWF A;  3S4E A;  5K9V A;  1C83 A;  3I36 A;  1KAK A;  1C88 A;  1Q6T A;  3V0I A;  2QBQ A;  2I6P A;  2I6J A;  2PA5 A;  2CM2 A;  1NNY A;  3QCM A;  2AZR A;  3GXH A;  3RGQ A;  3QCL A;  2F6W A;  3QCH A;  3QCB A;  2A8B A;  3H2X A;  4HJQ A;  1P15 A;  3LJ8 A;  4WU2 A;  1NZ7 A;  2CFV A;  1Q1M A;  4GRY A;  4H1O A;  2H4V A;  2PBN A;  3ZM1 A;  2CNG A;  3QCI A;  2G6Z A;  5KA1 A;  5AWX A;  4JNB A;  4QBE A;  2H02 A;  1G1F A;  1YPT A;  2M3V A;  2I4H A;  1ZZW A;  2MBC A;  2I1Y A;  2I4G A;  2NT7 A;  1ZC0 A;  1M3G A;  1PTY A;  4J51 A;  5GTJ A;  1U24 A;  2YDU A;  1Q6J A;  2I6M A;  2OOQ A;  1XXP A; 
#chains in the Genus database with same CATH topology
 3AWG A;  1GQQ A;  4ZIY A;  2QEP A;  3LK7 A;  2B07 A;  2HNQ A;  2FH7 A;  1OHC A;  3F9A A;  1T4J A;  2QBP A;  1RXD A;  4RI4 A;  1T48 A;  4GE5 A;  2HCM A;  3PS5 A;  2Y66 A;  1FPR A;  3D44 A;  3GXG A;  4ERC A;  1YGU A;  2P6X A;  1G1H A;  3OMH A;  1YTS A;  2Q05 A;  3MMJ A;  4QBW A;  4I8N A;  2NT2 A;  2CM8 A;  2VEV A;  2BZL A;  4YAA A;  5K23 A;  2I75 A;  1BZC A;  4HRF A;  1I9T A;  1PTT A;  4GE2 A;  2BGE A;  5KAC A;  2HXP A;  2VEY A;  1OET A;  3O4T A;  1VHR A;  3D42 A;  4R30 A;  2QCT A;  4WTY A;  2GP0 A;  4OHI A;  2GCA A;  1XXV A;  1EEO A;  2B3O A;  2HB1 A;  2H03 A;  2VEU A;  5K22 A;  3O4U A;  2GC6 A;  1E8C A;  3N0A A;  2WGP A;  1JLN A;  2B4S A;  2PQ5 A;  1OEO X;  4ZI4 A;  2H4K A;  1I57 A;  4B04 A;  2RF6 A;  4NWG A;  1PXH A;  1XRI A;  2IMG A;  2BV5 A;  1U25 A;  4QDI A;  5KA0 A;  5KA2 A;  2WTZ A;  2CMB A;  2QBS A;  3ZMP A;  1QXK A;  4BUC A;  2A3K A;  3QCE A;  5KA3 A;  1ZCK A;  4KI9 A;  2F46 A;  5KA9 A;  2HNP A;  5KAD A;  2OC3 A;  4UAG A;  4DGP A;  3QCJ A;  2I5X A;  2Y2F A;  2NTA A;  1OES A;  2ZN7 A;  3RZ2 A;  3V0E A;  3CM3 A;  4RI5 A;  1LQF A;  2CNH A;  2CMA A;  2Y1O A;  3V0F A;  1O5Z A;  2C46 A;  3QCD A;  1G4U S;  4QUM A;  1GFY A;  4CVM A;  1ONZ A;  1C84 A;  4WU3 A;  4JBC A;  3S3E A;  3U96 A;  2CNF A;  3EAX A;  2CM7 A;  1OHE A;  2DXP A;  2QBR A;  3EU0 A;  2R0B A;  1KAV A;  2I6O A;  3RGO A;  1T49 A;  2QDM A;  4NX8 A;  1BZH A;  5K24 A;  3MVN A;  3ZMQ A;  3I7Z A;  3QKP A;  2ESB A;  2X5O A;  3ZM2 A;  1W78 A;  4JMK A;  1L8G A;  3BRH A;  1FGS A;  1JF7 A;  4Y14 A;  4S0G A;  2CNE A;  3HN7 A;  1ONY A;  1NWE A;  4H34 A;  3ZV2 A;  1FQ1 A;  4BPC A;  1Q6P A;  2PT0 A;  1XBO A;  2Y96 A;  4Z6B A;  4D3Q A;  1EEH A;  1YFO A;  1Q6M A;  3V0H A;  1XM2 A;  2BGD A;  1LAR A;  2VTE A;  5IBS A;  1L8K A;  3NRS A;  1LYV A;  1Q6N A;  4NWF A;  2HVL A;  1MKP A;  2F6Y A;  2UAG A;  3PYZ A;  2I42 A;  5EHR A;  3EZZ A;  2C7S A;  3NME A;  1NL9 A;  2F6T A;  1PA9 A;  4RH9 A;  4PYH A;  4WOH A;  5KA7 A;  2I4E A;  1V3A A;  5J8R A;  3D1H A;  1ZCL A;  1FPZ A;  1BZJ A;  1R6H A;  3F41 A;  4PVG A;  1NO6 A;  5IBM A;  3ZM5 A;  4OHL A;  4HV4 A;  1JBW A;  3M4U A;  2F70 A;  2AM2 A;  2Q47 A;  1PYN A;  4OHD A;  4GFV A;  3MOW A;  5BX1 A;  4GRZ A;  4ICZ A;  4NND A;  1WAX A;  2JFG A;  1P3D A;  1YTW A;  1G7F A;  2F6F A;  2Y68 A;  4JMJ A;  3S3H A;  5LXQ B;  1GQY A;  2QCJ A;  2UUO A;  1U26 A;  2FJN A;  3V0D A;  1PTU A;  3D1Q A;  5KAB A;  3QKQ A;  2VOR A;  3V0J A;  5A5F A;  5M43 A;  4ZRT A;  1G1G A;  1JBV A;  5BZX A;  1J4X A;  2HC1 A;  4RDD A;  1RPM A;  2P4D A;  3F9B A;  2CJZ A;  2H04 A;  2E0T A;  2SHP A;  4OHE A;  1X24 A;  3S3F A;  2VEW A;  2B4U A;  4QAH A;  4R0T A;  3D9C A;  3QCN A;  2H4G A;  5A5E A;  5KA8 A;  2I6I A;  2JFF A;  2F00 A;  2NZ6 A;  1OHD A;  4GE6 A;  2J16 B;  2QDP A;  3O3L A;  2NLK A;  5BZZ A;  1GG4 A;  2B4O A;  5K9W A;  2CMC A;  1PA1 A;  3QCZ A;  2GWO A;  4C12 A;  3D1O A;  1OEV A;  2F71 A;  4YR8 B;  5I6V A;  2UUP A;  1P31 A;  1QZ0 A;  3BM8 A;  4QUN A;  1E0D A;  4RKK A;  2NV5 A;  3A5J A;  4DGX A;  3ZM6 A;  1A5Y A;  1GWZ A;  3O5X A;  2J17 A;  1PH0 A;  1I9S A;  2XPC A;  3S3K A;  4MBB A;  2WJP A;  3F81 A;  4BUB A;  2I3R A;  4HJP A;  1YZ4 A;  2F6V A;  4NYH A;  2Y67 A;  2AHS A;  2F6Z A;  3ZM3 A;  4Y2E A;  1G7G A;  1Q6S A;  1C87 A;  2PI7 A;  4RHG A;  2J16 A;  2ZMM A;  3B7O A;  2B4P A;  4KYR A;  3EMU A;  1YTN A;  3ZL8 A;  1ECV A;  2HY3 A;  2I3U A;  3V0G A;  2BIJ A;  2OUD A;  1AAX A;  4CVL A;  4GS0 A;  4AZ1 A;  3MOZ A;  1G4W R;  2FJM A;  3OLR A;  4D3P A;  3BLU A;  5BUG A;  2G59 A;  1PTV A;  1D5R A;  2B49 A;  3RO1 A;  1EEN A;  5K25 A;  3QCC A;  4KYQ A;  2AM1 A;  3A5K A;  3QCK A;  4BJO A;  3QCF A;  3BLT A;  1J6U A;  2CM3 A;  4GFU A;  5MMZ B;  1WRM A;  4TVV A;  2VTD A;  5EHP A;  3I80 A;  5HDE A;  2OZ5 A;  1NWL A;  4QAP A;  5KA4 A;  3S4O A;  1OEU A;  2GC5 A;  2GJT A;  3EB1 A;  2CNI A;  4IKC A;  3F99 A;  1SUG A;  4RH5 A;  4CVK A;  2PSZ A;  2JJD A;  2HC2 A;  3QCG A;  1YN9 A;  2VEX A;  3O4S A;  3ZM0 A;  3CWE A;  4D3R A;  1C85 A;  3AWE A;  4ZN5 A;  1C86 A;  4R0S A;  1YGR A;  2QDC A;  3SR9 A;  3AWF A;  1OEM X;  4OHH A;  3UAG A;  5KAA A;  1YWF A;  1WCH A;  3SME A;  4GWF A;  3S4E A;  5K9V A;  1C83 A;  3I36 A;  1KAK A;  1C88 A;  1Q6T A;  2XJA A;  3V0I A;  2QBQ A;  2I6P A;  2I6J A;  2PA5 A;  2CM2 A;  1NNY A;  3QCM A;  4C13 A;  1W7K A;  2AZR A;  3GXH A;  3RGQ A;  3QCL A;  2F6W A;  3QCH A;  3QCB A;  2A8B A;  2GCB A;  3H2X A;  1P15 A;  4HJQ A;  1UAG A;  3LJ8 A;  4WU2 A;  1NZ7 A;  2CFV A;  1Q1M A;  4QF5 A;  4GRY A;  4H1O A;  2H4V A;  2PBN A;  3ZM1 A;  2CNG A;  3QCI A;  2G6Z A;  3N2A A;  5KA1 A;  5AWX A;  4JNB A;  4QBE A;  2H02 A;  1G1F A;  1YPT A;  2M3V A;  2JFH A;  2I4H A;  1ZZW A;  2MBC A;  2I1Y A;  2I4G A;  2NT7 A;  1ZC0 A;  1M3G A;  1PTY A;  4J51 A;  5GTJ A;  1U24 A;  2YDU A;  1Q6J A;  2I6M A;  2OOQ A;  2VOS A;  1XXP A; 
#chains in the Genus database with same CATH homology
 3AWG A;  2QEP A;  2B07 A;  2HNQ A;  2FH7 A;  1OHC A;  3F9A A;  1T4J A;  2QBP A;  1RXD A;  4RI4 A;  1T48 A;  4GE5 A;  2HCM A;  3PS5 A;  1FPR A;  3D44 A;  3GXG A;  4ERC A;  1YGU A;  2P6X A;  1G1H A;  3OMH A;  1YTS A;  2Q05 A;  3MMJ A;  4QBW A;  4I8N A;  2NT2 A;  2CM8 A;  2VEV A;  2BZL A;  4YAA A;  5K23 A;  2I75 A;  1BZC A;  4HRF A;  1I9T A;  1PTT A;  4GE2 A;  2BGE A;  5KAC A;  2HXP A;  2VEY A;  1OET A;  3O4T A;  1VHR A;  3D42 A;  4R30 A;  2QCT A;  4WTY A;  2GP0 A;  4OHI A;  1XXV A;  1EEO A;  2B3O A;  2HB1 A;  2H03 A;  2VEU A;  5K22 A;  3O4U A;  3N0A A;  2WGP A;  1JLN A;  2B4S A;  2PQ5 A;  1OEO X;  4ZI4 A;  2H4K A;  1I57 A;  4B04 A;  2RF6 A;  4NWG A;  1PXH A;  1XRI A;  2IMG A;  2BV5 A;  1U25 A;  5KA0 A;  5KA2 A;  2CMB A;  2QBS A;  3ZMP A;  1QXK A;  5KA3 A;  2A3K A;  3QCE A;  1ZCK A;  4KI9 A;  2F46 A;  5KA9 A;  2HNP A;  5KAD A;  2OC3 A;  4DGP A;  3QCJ A;  2I5X A;  2Y2F A;  2NTA A;  1OES A;  2ZN7 A;  3RZ2 A;  3V0E A;  3CM3 A;  4RI5 A;  1LQF A;  2CNH A;  2CMA A;  3V0F A;  2C46 A;  3QCD A;  1G4U S;  4QUM A;  1GFY A;  1ONZ A;  1C84 A;  4WU3 A;  4JBC A;  3S3E A;  3U96 A;  2CNF A;  3EAX A;  2CM7 A;  1OHE A;  2DXP A;  2QBR A;  3EU0 A;  2R0B A;  1KAV A;  2I6O A;  3RGO A;  1T49 A;  2QDM A;  4NX8 A;  1BZH A;  5K24 A;  3ZMQ A;  3I7Z A;  3QKP A;  2ESB A;  3ZM2 A;  4JMK A;  1L8G A;  3BRH A;  1JF7 A;  4Y14 A;  4S0G A;  2CNE A;  1ONY A;  1NWE A;  4H34 A;  3ZV2 A;  1FQ1 A;  4BPC A;  1Q6P A;  2PT0 A;  1XBO A;  2Y96 A;  4Z6B A;  4D3Q A;  1YFO A;  1Q6M A;  3V0H A;  1XM2 A;  2BGD A;  1LAR A;  5IBS A;  1L8K A;  1LYV A;  1Q6N A;  4NWF A;  2HVL A;  1MKP A;  2F6Y A;  2I42 A;  5EHR A;  3EZZ A;  2C7S A;  3NME A;  1NL9 A;  2F6T A;  1PA9 A;  4RH9 A;  4PYH A;  4WOH A;  5KA7 A;  2I4E A;  1V3A A;  5J8R A;  3D1H A;  1ZCL A;  1FPZ A;  1BZJ A;  1R6H A;  3F41 A;  4PVG A;  1NO6 A;  5IBM A;  4OHL A;  3M4U A;  2F70 A;  2Q47 A;  1PYN A;  4OHD A;  4GFV A;  3MOW A;  5BX1 A;  4GRZ A;  4ICZ A;  4NND A;  1WAX A;  1YTW A;  1G7F A;  2F6F A;  4JMJ A;  3S3H A;  5LXQ B;  2QCJ A;  1U26 A;  2FJN A;  3V0D A;  1PTU A;  3D1Q A;  5KAB A;  3QKQ A;  3V0J A;  5M43 A;  4ZRT A;  1G1G A;  5BZX A;  1J4X A;  2HC1 A;  4RDD A;  1RPM A;  2P4D A;  3F9B A;  2CJZ A;  2H04 A;  2E0T A;  2SHP A;  4OHE A;  1X24 A;  3S3F A;  2VEW A;  2B4U A;  4QAH A;  4R0T A;  3D9C A;  3QCN A;  2H4G A;  5KA8 A;  2I6I A;  2NZ6 A;  1OHD A;  4GE6 A;  2J16 B;  2QDP A;  3O3L A;  2NLK A;  5BZZ A;  2B4O A;  5K9W A;  2CMC A;  1PA1 A;  2GWO A;  3D1O A;  1OEV A;  2F71 A;  4YR8 B;  5I6V A;  1QZ0 A;  3BM8 A;  4QUN A;  4RKK A;  2NV5 A;  3A5J A;  4DGX A;  1A5Y A;  1GWZ A;  3O5X A;  2J17 A;  1PH0 A;  1I9S A;  3S3K A;  4MBB A;  3F81 A;  2I3R A;  4HJP A;  1YZ4 A;  2F6V A;  4NYH A;  2AHS A;  2F6Z A;  3ZM3 A;  4Y2E A;  1G7G A;  1Q6S A;  1C87 A;  2PI7 A;  4RHG A;  2J16 A;  2ZMM A;  3B7O A;  2B4P A;  4KYR A;  3EMU A;  1YTN A;  1ECV A;  2HY3 A;  2I3U A;  3V0G A;  2BIJ A;  2OUD A;  1AAX A;  4GS0 A;  4AZ1 A;  3MOZ A;  1G4W R;  2FJM A;  3OLR A;  4D3P A;  3BLU A;  5BUG A;  2G59 A;  1PTV A;  1D5R A;  2B49 A;  3RO1 A;  1EEN A;  5K25 A;  3QCC A;  4KYQ A;  3A5K A;  3QCK A;  4BJO A;  3QCF A;  3BLT A;  2CM3 A;  4GFU A;  5MMZ B;  1WRM A;  4TVV A;  5EHP A;  3I80 A;  5HDE A;  2OZ5 A;  1NWL A;  4QAP A;  5KA4 A;  3S4O A;  1OEU A;  2GJT A;  3EB1 A;  2CNI A;  4IKC A;  3F99 A;  1SUG A;  4RH5 A;  2PSZ A;  2JJD A;  2HC2 A;  3QCG A;  1YN9 A;  2VEX A;  3O4S A;  3ZM0 A;  3CWE A;  4D3R A;  1C85 A;  3AWE A;  4ZN5 A;  1C86 A;  4R0S A;  1YGR A;  2QDC A;  3SR9 A;  3AWF A;  1OEM X;  4OHH A;  5KAA A;  1YWF A;  1WCH A;  3SME A;  4GWF A;  3S4E A;  5K9V A;  1C83 A;  3I36 A;  1KAK A;  1C88 A;  1Q6T A;  3V0I A;  2QBQ A;  2I6P A;  2I6J A;  2PA5 A;  2CM2 A;  1NNY A;  3QCM A;  2AZR A;  3GXH A;  3RGQ A;  3QCL A;  2F6W A;  3QCH A;  3QCB A;  2A8B A;  3H2X A;  4HJQ A;  1P15 A;  3LJ8 A;  4WU2 A;  1NZ7 A;  2CFV A;  1Q1M A;  4GRY A;  4H1O A;  2H4V A;  2PBN A;  3ZM1 A;  2CNG A;  3QCI A;  2G6Z A;  5KA1 A;  5AWX A;  4JNB A;  4QBE A;  2H02 A;  1G1F A;  1YPT A;  2M3V A;  2I4H A;  1ZZW A;  2MBC A;  2I1Y A;  2I4G A;  2NT7 A;  1ZC0 A;  1M3G A;  1PTY A;  4J51 A;  5GTJ A;  1U24 A;  2YDU A;  1Q6J A;  2I6M A;  2OOQ A;  1XXP A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2ZN7A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations