2A8BA

Crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
283
structure length
283
Chain Sequence
IPSRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAET
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase R
total genus 99
structure length 283
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2a8bA00
1YWFA 2NLKA 4GE6A 4PYHA 2CNHA 3H2XA 1VHRA 2R0BA 1SUGA 5MMZB 2QBSA 2I6PA 3O4UA 4RDDA 1ECVA 1YTSA 5IBSA 4OHIA 4OHEA 2I6OA 4H34A 2F6FA 2HNPA 3V0HA 2I42A 1LARA 4QAPA 2CNFA 1OESA 2FJMA 1PYNA 3S4EA 3D1OA 1G1FA 1J4XA 1I9TA 1X24A 3RZ2A 1C85A 2QBQA 4QUMA 2WGPA 4GRYA 2OZ5A 4JMKA 2JJDA 2PA5A 1Q1MA 3SMEA 4DGPA 2BGEA 1M3GA 3F99A 4RI5A 5KA9A 2VEXA 5KAAA 2CFVA 5K25A 1YTNA 4I8NA 1YTWA 4YR8B 2BZLA 1QZ0A 2B4SA 1YGUA 3MOZA 5BX1A 1XM2A 2HC2A 3QCEA 4D3QA 5K22A 2PQ5A 2Q05A 4KYQA 4OHDA 4ZN5A 1L8GA 4QAHA 2F6WA 4Y2EA 2AHSA 3EZZA 3QCGA 1G1HA 4MBBA 4JNBA 3V0DA 2I6IA 4BPCA 2CM2A 1AAXA 2FH7A 3OMHA 4HJPA 4ZRTA 2NTAA 1WRMA 5BZZA 2F6YA 2PBNA 3EU0A 4RH5A 2I3UA 3BLUA 5EHRA 2CM7A 2ZN7A 5KA8A 2CMCA 1OEVA 1T48A 4RHGA 3QCCA 3RGQA 2ESBA 4QUNA 3QCBA 3BM8A 4R30A 1EEOA 1OHEA 3D1HA 4NYHA 4D3RA 2I4HA 4HJQA 1G4US 2H04A 1ZCLA 3B7OA 4NWGA 4RKKA 3S4OA 2A3KA 2OC3A 2GJTA 4Y14A 3F9AA 2C7SA 1OHCA 3QCDA 3QCMA 1GWZA 2H4GA 5BZXA 1PA9A 3ZM1A 3ZV2A 1JLNA 2PSZA 5K23A 1U26A 2CNIA 2HXPA 1OEOX 3V0FA 2I4EA 3QCNA 2GP0A 4WU3A 3I7ZA 4J51A 1XBOA 3ZM0A 1ONZA 1A5YA 3SR9A 2QDMA 1FPZA 3A5JA 2F71A 3QCIA 2P4DA 2Y2FA 1WCHA 1ZC0A 5KACA 4GFVA 1R6HA 2B4UA 4NNDA 3RO1A 5KA3A 1NNYA 4PVGA 3CM3A 4GS0A 4GFUA 1KAVA 5KABA 1YZ4A 3V0GA 2QCTA 1U24A 1C86A 3NMEA 3F81A 1D5RA 3QCLA 4JBCA 2CMBA 2CM8A 2P6XA 3D9CA 1P15A 2I1YA 3V0IA 4ZI4A 1T49A 2H03A 1JF7A 2B4PA 1NL9A 4BJOA 1BZHA 3D1QA 2SHPA 2RF6A 1PTTA 5HDEA 1YGRA 3EAXA 4QBEA 2Y96A 2B07A 2PT0A 1C83A 3D42A 4AZ1A 4WTYA 4TVVA 3U96A 3QCFA 1FQ1A 4S0GA 2H4KA 1PTYA 2C46A 3AWEA 3ZM3A 4QBWA 5LXQB 2F6ZA 3S3EA 2GWOA 2NV5A 1EENA 3F41A 3S3KA 2VEYA 3GXHA 4HRFA 2CNGA 2QDPA 2HB1A 3ZMPA 1ONYA 3QCKA 1NWLA 3BRHA 2VEWA 4Z6BA 3EMUA 4ICZA 2HC1A 5BUGA 2J16B 1XXPA 2B4OA 2FJNA 4RI4A 5KA0A 1FPRA 2NT2A 1Q6NA 2B3OA 1YFOA 1C88A 2BIJA 1MKPA 3ZM2A 5I6VA 1PA1A 4IKCA 1G7GA 3OLRA 3O4SA 1GFYA 2OOQA 1BZCA 2VEVA 2F46A 2J17A 4OHLA 1C87A 4JMJA 1PXHA 3D44A 4GE5A 5K9VA 3EB1A 1LQFA 5EHPA 2DXPA 3V0EA 4KYRA 1KAKA 3MMJA 3O4TA 2I4GA 4KI9A 4GWFA 4GRZA 1PTVA 2QBPA 1G4WR 5KADA 2HVLA 5KA2A 5M43A 3GXGA 1PTUA 2QDCA 1RXDA 1NO6A 1QXKA 4R0TA 1Q6SA 1U25A 2NT7A 1YPTA 2F70A 3QKPA 4WOHA 2I75A 2J16A 4OHHA 2BV5A 2F6VA 4NX8A 3LJ8A 2NZ6A 1G7FA 2Q47A 1I9SA 2IMGA 5J8RA 1XRIA 2HCMA 1ZZWA 1PH0A 2CM3A 2VEUA 2MBCA 2OUDA 2CNEA 3O5XA 1T4JA 2I6JA 2B49A 2YDUA 2QCJA 1OETA 2G59A 3BLTA 3M4UA 5K9WA 3N0AA 3I80A 1L8KA 1OHDA 2F6TA 3AWGA 2HY3A 2QEPA 4YAAA 1NZ7A 1WAXA 2CJZA 4R0SA 5K24A 1Q6MA 2M3VA 3I36A 3O3LA 4GE2A 4RH9A 2PI7A 4D3PA 5KA7A 5AWXA 2H02A 4H1OA 3S3HA 2I6MA 1RPMA 3S3FA 1Q6JA 3ZMQA 1XXVA 5GTJA 4ERCA 1V3AA 1YN9A 3AWFA 2I5XA 1Q6TA 3MOWA 2AZRA 2I3RA 3QKQA 2QBRA 3QCHA 2H4VA 3V0JA 3RGOA 3A5KA 1OEUA 2CMAA 5KA4A 2BGDA 1BZJA 2HNQA 1Q6PA 1LYVA 3F9BA 3QCJA 2E0TA 3CWEA 3PS5A 1OEMX 4NWFA 1C84A 1NWEA 4B04A 1ZCKA 2A8BA 2G6ZA 1I57A 4WU2A 5IBMA 5KA1A 4DGXA 1G1GA 2ZMMA
chains in the Genus database with same CATH superfamily
1YWFA 2NLKA 4GE6A 4PYHA 2CNHA 3H2XA 1VHRA 2R0BA 1SUGA 2VTDA 5MMZB 2QBSA 2I6PA 3O4UA 4RDDA 1ECVA 1YTSA 5IBSA 4OHIA 4OHEA 2I6OA 4H34A 2F6FA 2HNPA 3V0HA 2I42A 1LARA 4QAPA 2CNFA 1OESA 2FJMA 1PYNA 3S4EA 3D1OA 1G1FA 5A5EA 1J4XA 1I9TA 1X24A 3ZL8A 1W78A 3RZ2A 1C85A 2QBQA 3MVNA 4QUMA 2WGPA 4GRYA 1J6UA 2OZ5A 4JMKA 2JJDA 2PA5A 1Q1MA 3SMEA 4DGPA 2BGEA 1M3GA 2VORA 3F99A 4RI5A 5KA9A 2VEXA 5KAAA 2Y66A 2CFVA 5K25A 1YTNA 4I8NA 1YTWA 4YR8B 2BZLA 1QZ0A 2B4SA 1YGUA 3MOZA 5BX1A 1XM2A 2HC2A 3QCEA 4D3QA 5K22A 2PQ5A 2Q05A 4BUCA 4KYQA 4OHDA 2Y67A 4ZN5A 1L8GA 4QAHA 2F6WA 4Y2EA 2AHSA 3EZZA 3QCGA 1G1HA 4MBBA 4JNBA 3V0DA 2I6IA 4BPCA 2CM2A 1AAXA 2FH7A 3OMHA 4HJPA 4ZRTA 2NTAA 1WRMA 5BZZA 2VOSA 2F6YA 2PBNA 3EU0A 4RH5A 2I3UA 3BLUA 5EHRA 2CM7A 1W7KA 2ZN7A 5KA8A 2CMCA 1OEVA 1T48A 4RHGA 3QCCA 3RGQA 2ESBA 4QUNA 1E8CA 3LK7A 3QCBA 3BM8A 4R30A 1EEOA 1OHEA 3D1HA 4NYHA 4D3RA 1O5ZA 2I4HA 4HJQA 1G4US 1GG4A 2H04A 1ZCLA 3B7OA 4NWGA 4BUBA 4RKKA 2GCAA 3S4OA 2A3KA 2OC3A 2GJTA 4Y14A 3F9AA 2C7SA 1OHCA 3QCDA 3QCMA 4QF5A 4CVMA 1GWZA 2H4GA 5BZXA 1PA9A 3ZM1A 3ZV2A 1JLNA 2PSZA 5K23A 1U26A 2CNIA 2HXPA 1OEOX 3V0FA 3N2AA 1EEHA 2I4EA 3QCNA 2GP0A 4WU3A 2XJAA 3I7ZA 4J51A 1XBOA 2F00A 2Y68A 3ZM0A 1ONZA 1A5YA 3SR9A 2QDMA 1FPZA 3A5JA 2F71A 3QCIA 2P4DA 2Y2FA 1WCHA 1ZC0A 5KACA 4GFVA 1E0DA 1R6HA 2B4UA 3QCZA 4NNDA 3RO1A 5KA3A 1NNYA 4PVGA 3CM3A 4GS0A 4GFUA 2JFHA 1KAVA 5KABA 1YZ4A 2UAGA 3V0GA 2QCTA 1U24A 1C86A 3NMEA 3F81A 1D5RA 3QCLA 1JBVA 4JBCA 2CMBA 2CM8A 2P6XA 3D9CA 1P15A 2I1YA 3V0IA 4ZI4A 1JBWA 1T49A 2H03A 1FGSA 3HN7A 1JF7A 2B4PA 1NL9A 4BJOA 1BZHA 3D1QA 2SHPA 2RF6A 2GC5A 1PTTA 5HDEA 1YGRA 3EAXA 2Y1OA 4QBEA 2Y96A 4C12A 5A5FA 2B07A 2PT0A 1C83A 3D42A 4AZ1A 4WTYA 4TVVA 3U96A 3QCFA 1FQ1A 4S0GA 2H4KA 1PTYA 2C46A 3AWEA 3ZM3A 3NRSA 4QBWA 5LXQB 2F6ZA 3S3EA 2GWOA 2UUPA 2NV5A 1EENA 2X5OA 3F41A 3S3KA 2VEYA 3GXHA 4HRFA 2CNGA 2QDPA 2HB1A 3ZMPA 1ONYA 3QCKA 1NWLA 3BRHA 3UAGA 2VEWA 4Z6BA 3EMUA 4ICZA 2HC1A 5BUGA 2J16B 1XXPA 2B4OA 2FJNA 4RI4A 5KA0A 1FPRA 2NT2A 1Q6NA 2B3OA 1YFOA 1C88A 2BIJA 1MKPA 2VTEA 3ZM2A 5I6VA 1PA1A 4QDIA 4IKCA 1G7GA 3OLRA 3O4SA 2WJPA 1GFYA 2AM1A 2OOQA 1BZCA 2VEVA 2F46A 2J17A 4OHLA 1C87A 4JMJA 1PXHA 3D44A 4GE5A 5K9VA 3EB1A 2XPCA 1GQYA 1LQFA 5EHPA 2DXPA 3V0EA 4KYRA 1KAKA 3MMJA 3O4TA 2I4GA 4KI9A 4GWFA 4GRZA 1PTVA 2QBPA 1G4WR 5KADA 1GQQA 2JFGA 1P31A 2HVLA 5KA2A 5M43A 3GXGA 1PTUA 2QDCA 1RXDA 1NO6A 1QXKA 4R0TA 1Q6SA 1U25A 2NT7A 1YPTA 2F70A 3QKPA 4WOHA 2I75A 2J16A 4OHHA 2BV5A 2F6VA 4NX8A 3LJ8A 2NZ6A 1G7FA 2Q47A 1I9SA 2IMGA 5J8RA 1XRIA 4CVLA 2HCMA 1ZZWA 2GC6A 1PH0A 2CM3A 2VEUA 2MBCA 2OUDA 2CNEA 3O5XA 1T4JA 2I6JA 2B49A 2YDUA 2QCJA 1P3DA 2WTZA 1OETA 2G59A 3BLTA 3M4UA 5K9WA 3N0AA 3I80A 1L8KA 1OHDA 2F6TA 3AWGA 2HY3A 2QEPA 4YAAA 1NZ7A 1WAXA 2CJZA 4R0SA 5K24A 1Q6MA 2M3VA 4ZIYA 3I36A 2AM2A 4UAGA 3PYZA 3O3LA 4GE2A 4RH9A 2PI7A 2JFFA 4D3PA 5KA7A 5AWXA 2H02A 4H1OA 3S3HA 2I6MA 1RPMA 1UAGA 3S3FA 4C13A 1Q6JA 3ZMQA 1XXVA 5GTJA 3ZM6A 4ERCA 1V3AA 1YN9A 3AWFA 2I5XA 3ZM5A 1Q6TA 3MOWA 2AZRA 2UUOA 2I3RA 3QKQA 4HV4A 2QBRA 3QCHA 2H4VA 3V0JA 3RGOA 3A5KA 1OEUA 2CMAA 5KA4A 2BGDA 1BZJA 2HNQA 1Q6PA 1LYVA 3F9BA 3QCJA 2E0TA 2GCBA 3CWEA 3PS5A 1OEMX 4NWFA 1C84A 1NWEA 4B04A 1ZCKA 2A8BA 2G6ZA 1I57A 4WU2A 5IBMA 5KA1A 4DGXA 4CVKA 1G1GA 2ZMMA
chains in the Genus database with same CATH topology
1YWFA 2NLKA 4GE6A 4PYHA 2CNHA 3H2XA 1VHRA 2R0BA 1SUGA 5MMZB 2QBSA 2I6PA 3O4UA 4RDDA 1ECVA 1YTSA 5IBSA 4OHIA 4OHEA 2I6OA 4H34A 2F6FA 2HNPA 3V0HA 2I42A 1LARA 4QAPA 2CNFA 1OESA 2FJMA 1PYNA 3S4EA 3D1OA 1G1FA 1J4XA 1I9TA 1X24A 3RZ2A 1C85A 2QBQA 4QUMA 2WGPA 4GRYA 2OZ5A 4JMKA 2JJDA 2PA5A 1Q1MA 3SMEA 4DGPA 2BGEA 1M3GA 3F99A 4RI5A 5KA9A 2VEXA 5KAAA 2CFVA 5K25A 1YTNA 4I8NA 1YTWA 4YR8B 2BZLA 1QZ0A 2B4SA 1YGUA 3MOZA 5BX1A 1XM2A 2HC2A 3QCEA 4D3QA 5K22A 2PQ5A 2Q05A 4KYQA 4OHDA 4ZN5A 1L8GA 4QAHA 2F6WA 4Y2EA 2AHSA 3EZZA 3QCGA 1G1HA 4MBBA 4JNBA 3V0DA 2I6IA 4BPCA 2CM2A 1AAXA 2FH7A 3OMHA 4HJPA 4ZRTA 2NTAA 1WRMA 5BZZA 2F6YA 2PBNA 3EU0A 4RH5A 2I3UA 3BLUA 5EHRA 2CM7A 2ZN7A 5KA8A 2CMCA 1OEVA 1T48A 4RHGA 3QCCA 3RGQA 2ESBA 4QUNA 3QCBA 3BM8A 4R30A 1EEOA 1OHEA 3D1HA 4NYHA 4D3RA 2I4HA 4HJQA 1G4US 2H04A 1ZCLA 3B7OA 4NWGA 4RKKA 3S4OA 2A3KA 2OC3A 2GJTA 4Y14A 3F9AA 2C7SA 1OHCA 3QCDA 3QCMA 1GWZA 2H4GA 5BZXA 1PA9A 3ZM1A 3ZV2A 1JLNA 2PSZA 5K23A 1U26A 2CNIA 2HXPA 1OEOX 3V0FA 2I4EA 3QCNA 2GP0A 4WU3A 3I7ZA 4J51A 1XBOA 3ZM0A 1ONZA 1A5YA 3SR9A 2QDMA 1FPZA 3A5JA 2F71A 3QCIA 2P4DA 2Y2FA 1WCHA 1ZC0A 5KACA 4GFVA 1R6HA 2B4UA 4NNDA 3RO1A 5KA3A 1NNYA 4PVGA 3CM3A 4GS0A 4GFUA 1KAVA 5KABA 1YZ4A 3V0GA 2QCTA 1U24A 1C86A 3NMEA 3F81A 1D5RA 3QCLA 4JBCA 2CMBA 2CM8A 2P6XA 3D9CA 1P15A 2I1YA 3V0IA 4ZI4A 1T49A 2H03A 1JF7A 2B4PA 1NL9A 4BJOA 1BZHA 3D1QA 2SHPA 2RF6A 1PTTA 5HDEA 1YGRA 3EAXA 4QBEA 2Y96A 2B07A 2PT0A 1C83A 3D42A 4AZ1A 4WTYA 4TVVA 3U96A 3QCFA 1FQ1A 4S0GA 2H4KA 1PTYA 2C46A 3AWEA 3ZM3A 4QBWA 5LXQB 2F6ZA 3S3EA 2GWOA 2NV5A 1EENA 3F41A 3S3KA 2VEYA 3GXHA 4HRFA 2CNGA 2QDPA 2HB1A 3ZMPA 1ONYA 3QCKA 1NWLA 3BRHA 2VEWA 4Z6BA 3EMUA 4ICZA 2HC1A 5BUGA 2J16B 1XXPA 2B4OA 2FJNA 4RI4A 5KA0A 1FPRA 2NT2A 1Q6NA 2B3OA 1YFOA 1C88A 2BIJA 1MKPA 3ZM2A 5I6VA 1PA1A 4IKCA 1G7GA 3OLRA 3O4SA 1GFYA 2OOQA 1BZCA 2VEVA 2F46A 2J17A 4OHLA 1C87A 4JMJA 1PXHA 3D44A 4GE5A 5K9VA 3EB1A 1LQFA 5EHPA 2DXPA 3V0EA 4KYRA 1KAKA 3MMJA 3O4TA 2I4GA 4KI9A 4GWFA 4GRZA 1PTVA 2QBPA 1G4WR 5KADA 2HVLA 5KA2A 5M43A 3GXGA 1PTUA 2QDCA 1RXDA 1NO6A 1QXKA 4R0TA 1Q6SA 1U25A 2NT7A 1YPTA 2F70A 3QKPA 4WOHA 2I75A 2J16A 4OHHA 2BV5A 2F6VA 4NX8A 3LJ8A 2NZ6A 1G7FA 2Q47A 1I9SA 2IMGA 5J8RA 1XRIA 2HCMA 1ZZWA 1PH0A 2CM3A 2VEUA 2MBCA 2OUDA 2CNEA 3O5XA 1T4JA 2I6JA 2B49A 2YDUA 2QCJA 1OETA 2G59A 3BLTA 3M4UA 5K9WA 3N0AA 3I80A 1L8KA 1OHDA 2F6TA 3AWGA 2HY3A 2QEPA 4YAAA 1NZ7A 1WAXA 2CJZA 4R0SA 5K24A 1Q6MA 2M3VA 3I36A 3O3LA 4GE2A 4RH9A 2PI7A 4D3PA 5KA7A 5AWXA 2H02A 4H1OA 3S3HA 2I6MA 1RPMA 3S3FA 1Q6JA 3ZMQA 1XXVA 5GTJA 4ERCA 1V3AA 1YN9A 3AWFA 2I5XA 1Q6TA 3MOWA 2AZRA 2I3RA 3QKQA 2QBRA 3QCHA 2H4VA 3V0JA 3RGOA 3A5KA 1OEUA 2CMAA 5KA4A 2BGDA 1BZJA 2HNQA 1Q6PA 1LYVA 3F9BA 3QCJA 2E0TA 3CWEA 3PS5A 1OEMX 4NWFA 1C84A 1NWEA 4B04A 1ZCKA 2A8BA 2G6ZA 1I57A 4WU2A 5IBMA 5KA1A 4DGXA 1G1GA 2ZMMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YWF A;  2NLK A;  4GE6 A;  4PYH A;  2CNH A;  3H2X A;  1VHR A;  2R0B A;  1SUG A;  5MMZ B;  2QBS A;  2I6P A;  3O4U A;  4RDD A;  1ECV A;  1YTS A;  5IBS A;  4OHI A;  4OHE A;  2I6O A;  4H34 A;  2F6F A;  2HNP A;  3V0H A;  2I42 A;  1LAR A;  4QAP A;  2CNF A;  1OES A;  2FJM A;  1PYN A;  3S4E A;  3D1O A;  1G1F A;  1J4X A;  1I9T A;  1X24 A;  3RZ2 A;  1C85 A;  2QBQ A;  4QUM A;  2WGP A;  4GRY A;  2OZ5 A;  4JMK A;  2JJD A;  2PA5 A;  1Q1M A;  3SME A;  4DGP A;  2BGE A;  1M3G A;  3F99 A;  4RI5 A;  5KA9 A;  2VEX A;  5KAA A;  2CFV A;  5K25 A;  1YTN A;  4I8N A;  1YTW A;  4YR8 B;  2BZL A;  1QZ0 A;  2B4S A;  1YGU A;  3MOZ A;  5BX1 A;  1XM2 A;  2HC2 A;  3QCE A;  4D3Q A;  5K22 A;  2PQ5 A;  2Q05 A;  4KYQ A;  4OHD A;  4ZN5 A;  1L8G A;  4QAH A;  2F6W A;  4Y2E A;  2AHS A;  3EZZ A;  3QCG A;  1G1H A;  4MBB A;  4JNB A;  3V0D A;  2I6I A;  4BPC A;  2CM2 A;  1AAX A;  2FH7 A;  3OMH A;  4HJP A;  4ZRT A;  2NTA A;  1WRM A;  5BZZ A;  2F6Y A;  2PBN A;  3EU0 A;  4RH5 A;  2I3U A;  3BLU A;  5EHR A;  2CM7 A;  2ZN7 A;  5KA8 A;  2CMC A;  1OEV A;  1T48 A;  4RHG A;  3QCC A;  3RGQ A;  2ESB A;  4QUN A;  3QCB A;  3BM8 A;  4R30 A;  1EEO A;  1OHE A;  3D1H A;  4NYH A;  4D3R A;  2I4H A;  4HJQ A;  1G4U S;  2H04 A;  1ZCL A;  3B7O A;  4NWG A;  4RKK A;  3S4O A;  2A3K A;  2OC3 A;  2GJT A;  4Y14 A;  3F9A A;  2C7S A;  1OHC A;  3QCD A;  3QCM A;  1GWZ A;  2H4G A;  5BZX A;  1PA9 A;  3ZM1 A;  3ZV2 A;  1JLN A;  2PSZ A;  5K23 A;  1U26 A;  2CNI A;  2HXP A;  1OEO X;  3V0F A;  2I4E A;  3QCN A;  2GP0 A;  4WU3 A;  3I7Z A;  4J51 A;  1XBO A;  3ZM0 A;  1ONZ A;  1A5Y A;  3SR9 A;  2QDM A;  1FPZ A;  3A5J A;  2F71 A;  3QCI A;  2P4D A;  2Y2F A;  1WCH A;  1ZC0 A;  5KAC A;  4GFV A;  1R6H A;  2B4U A;  4NND A;  3RO1 A;  5KA3 A;  1NNY A;  4PVG A;  3CM3 A;  4GS0 A;  4GFU A;  1KAV A;  5KAB A;  1YZ4 A;  3V0G A;  2QCT A;  1U24 A;  1C86 A;  3NME A;  3F81 A;  1D5R A;  3QCL A;  4JBC A;  2CMB A;  2CM8 A;  2P6X A;  3D9C A;  1P15 A;  2I1Y A;  3V0I A;  4ZI4 A;  1T49 A;  2H03 A;  1JF7 A;  2B4P A;  1NL9 A;  4BJO A;  1BZH A;  3D1Q A;  2SHP A;  2RF6 A;  1PTT A;  5HDE A;  1YGR A;  3EAX A;  4QBE A;  2Y96 A;  2B07 A;  2PT0 A;  1C83 A;  3D42 A;  4AZ1 A;  4WTY A;  4TVV A;  3U96 A;  3QCF A;  1FQ1 A;  4S0G A;  2H4K A;  1PTY A;  2C46 A;  3AWE A;  3ZM3 A;  4QBW A;  5LXQ B;  2F6Z A;  3S3E A;  2GWO A;  2NV5 A;  1EEN A;  3F41 A;  3S3K A;  2VEY A;  3GXH A;  4HRF A;  2CNG A;  2QDP A;  2HB1 A;  3ZMP A;  1ONY A;  3QCK A;  1NWL A;  3BRH A;  2VEW A;  4Z6B A;  3EMU A;  4ICZ A;  2HC1 A;  5BUG A;  2J16 B;  1XXP A;  2B4O A;  2FJN A;  4RI4 A;  5KA0 A;  1FPR A;  2NT2 A;  1Q6N A;  2B3O A;  1YFO A;  1C88 A;  2BIJ A;  1MKP A;  3ZM2 A;  5I6V A;  1PA1 A;  4IKC A;  1G7G A;  3OLR A;  3O4S A;  1GFY A;  2OOQ A;  1BZC A;  2VEV A;  2F46 A;  2J17 A;  4OHL A;  1C87 A;  4JMJ A;  1PXH A;  3D44 A;  4GE5 A;  5K9V A;  3EB1 A;  1LQF A;  5EHP A;  2DXP A;  3V0E A;  4KYR A;  1KAK A;  3MMJ A;  3O4T A;  2I4G A;  4KI9 A;  4GWF A;  4GRZ A;  1PTV A;  2QBP A;  1G4W R;  5KAD A;  2HVL A;  5KA2 A;  5M43 A;  3GXG A;  1PTU A;  2QDC A;  1RXD A;  1NO6 A;  1QXK A;  4R0T A;  1Q6S A;  1U25 A;  2NT7 A;  1YPT A;  2F70 A;  3QKP A;  4WOH A;  2I75 A;  2J16 A;  4OHH A;  2BV5 A;  2F6V A;  4NX8 A;  3LJ8 A;  2NZ6 A;  1G7F A;  2Q47 A;  1I9S A;  2IMG A;  5J8R A;  1XRI A;  2HCM A;  1ZZW A;  1PH0 A;  2CM3 A;  2VEU A;  2MBC A;  2OUD A;  2CNE A;  3O5X A;  1T4J A;  2I6J A;  2B49 A;  2YDU A;  2QCJ A;  1OET A;  2G59 A;  3BLT A;  3M4U A;  5K9W A;  3N0A A;  3I80 A;  1L8K A;  1OHD A;  2F6T A;  3AWG A;  2HY3 A;  2QEP A;  4YAA A;  1NZ7 A;  1WAX A;  2CJZ A;  4R0S A;  5K24 A;  1Q6M A;  2M3V A;  3I36 A;  3O3L A;  4GE2 A;  4RH9 A;  2PI7 A;  4D3P A;  5KA7 A;  5AWX A;  2H02 A;  4H1O A;  3S3H A;  2I6M A;  1RPM A;  3S3F A;  1Q6J A;  3ZMQ A;  1XXV A;  5GTJ A;  4ERC A;  1V3A A;  1YN9 A;  3AWF A;  2I5X A;  1Q6T A;  3MOW A;  2AZR A;  2I3R A;  3QKQ A;  2QBR A;  3QCH A;  2H4V A;  3V0J A;  3RGO A;  3A5K A;  1OEU A;  2CMA A;  5KA4 A;  2BGD A;  1BZJ A;  2HNQ A;  1Q6P A;  1LYV A;  3F9B A;  3QCJ A;  2E0T A;  3CWE A;  3PS5 A;  1OEM X;  4NWF A;  1C84 A;  1NWE A;  4B04 A;  1ZCK A;  2A8B A;  2G6Z A;  1I57 A;  4WU2 A;  5IBM A;  5KA1 A;  4DGX A;  1G1G A;  2ZMM A; 
#chains in the Genus database with same CATH topology
 1YWF A;  2NLK A;  4GE6 A;  4PYH A;  2CNH A;  3H2X A;  1VHR A;  2R0B A;  1SUG A;  2VTD A;  5MMZ B;  2QBS A;  2I6P A;  3O4U A;  4RDD A;  1ECV A;  1YTS A;  5IBS A;  4OHI A;  4OHE A;  2I6O A;  4H34 A;  2F6F A;  2HNP A;  3V0H A;  2I42 A;  1LAR A;  4QAP A;  2CNF A;  1OES A;  2FJM A;  1PYN A;  3S4E A;  3D1O A;  1G1F A;  5A5E A;  1J4X A;  1I9T A;  1X24 A;  3ZL8 A;  1W78 A;  3RZ2 A;  1C85 A;  2QBQ A;  3MVN A;  4QUM A;  2WGP A;  4GRY A;  1J6U A;  2OZ5 A;  4JMK A;  2JJD A;  2PA5 A;  1Q1M A;  3SME A;  4DGP A;  2BGE A;  1M3G A;  2VOR A;  3F99 A;  4RI5 A;  5KA9 A;  2VEX A;  5KAA A;  2Y66 A;  2CFV A;  5K25 A;  1YTN A;  4I8N A;  1YTW A;  4YR8 B;  2BZL A;  1QZ0 A;  2B4S A;  1YGU A;  3MOZ A;  5BX1 A;  1XM2 A;  2HC2 A;  3QCE A;  4D3Q A;  5K22 A;  2PQ5 A;  2Q05 A;  4BUC A;  4KYQ A;  4OHD A;  2Y67 A;  4ZN5 A;  1L8G A;  4QAH A;  2F6W A;  4Y2E A;  2AHS A;  3EZZ A;  3QCG A;  1G1H A;  4MBB A;  4JNB A;  3V0D A;  2I6I A;  4BPC A;  2CM2 A;  1AAX A;  2FH7 A;  3OMH A;  4HJP A;  4ZRT A;  2NTA A;  1WRM A;  5BZZ A;  2VOS A;  2F6Y A;  2PBN A;  3EU0 A;  4RH5 A;  2I3U A;  3BLU A;  5EHR A;  2CM7 A;  1W7K A;  2ZN7 A;  5KA8 A;  2CMC A;  1OEV A;  1T48 A;  4RHG A;  3QCC A;  3RGQ A;  2ESB A;  4QUN A;  1E8C A;  3LK7 A;  3QCB A;  3BM8 A;  4R30 A;  1EEO A;  1OHE A;  3D1H A;  4NYH A;  4D3R A;  1O5Z A;  2I4H A;  4HJQ A;  1G4U S;  1GG4 A;  2H04 A;  1ZCL A;  3B7O A;  4NWG A;  4BUB A;  4RKK A;  2GCA A;  3S4O A;  2A3K A;  2OC3 A;  2GJT A;  4Y14 A;  3F9A A;  2C7S A;  1OHC A;  3QCD A;  3QCM A;  4QF5 A;  4CVM A;  1GWZ A;  2H4G A;  5BZX A;  1PA9 A;  3ZM1 A;  3ZV2 A;  1JLN A;  2PSZ A;  5K23 A;  1U26 A;  2CNI A;  2HXP A;  1OEO X;  3V0F A;  3N2A A;  1EEH A;  2I4E A;  3QCN A;  2GP0 A;  4WU3 A;  2XJA A;  3I7Z A;  4J51 A;  1XBO A;  2F00 A;  2Y68 A;  3ZM0 A;  1ONZ A;  1A5Y A;  3SR9 A;  2QDM A;  1FPZ A;  3A5J A;  2F71 A;  3QCI A;  2P4D A;  2Y2F A;  1WCH A;  1ZC0 A;  5KAC A;  4GFV A;  1E0D A;  1R6H A;  2B4U A;  3QCZ A;  4NND A;  3RO1 A;  5KA3 A;  1NNY A;  4PVG A;  3CM3 A;  4GS0 A;  4GFU A;  2JFH A;  1KAV A;  5KAB A;  1YZ4 A;  2UAG A;  3V0G A;  2QCT A;  1U24 A;  1C86 A;  3NME A;  3F81 A;  1D5R A;  3QCL A;  1JBV A;  4JBC A;  2CMB A;  2CM8 A;  2P6X A;  3D9C A;  1P15 A;  2I1Y A;  3V0I A;  4ZI4 A;  1JBW A;  1T49 A;  2H03 A;  1FGS A;  3HN7 A;  1JF7 A;  2B4P A;  1NL9 A;  4BJO A;  1BZH A;  3D1Q A;  2SHP A;  2RF6 A;  2GC5 A;  1PTT A;  5HDE A;  1YGR A;  3EAX A;  2Y1O A;  4QBE A;  2Y96 A;  4C12 A;  5A5F A;  2B07 A;  2PT0 A;  1C83 A;  3D42 A;  4AZ1 A;  4WTY A;  4TVV A;  3U96 A;  3QCF A;  1FQ1 A;  4S0G A;  2H4K A;  1PTY A;  2C46 A;  3AWE A;  3ZM3 A;  3NRS A;  4QBW A;  5LXQ B;  2F6Z A;  3S3E A;  2GWO A;  2UUP A;  2NV5 A;  1EEN A;  2X5O A;  3F41 A;  3S3K A;  2VEY A;  3GXH A;  4HRF A;  2CNG A;  2QDP A;  2HB1 A;  3ZMP A;  1ONY A;  3QCK A;  1NWL A;  3BRH A;  3UAG A;  2VEW A;  4Z6B A;  3EMU A;  4ICZ A;  2HC1 A;  5BUG A;  2J16 B;  1XXP A;  2B4O A;  2FJN A;  4RI4 A;  5KA0 A;  1FPR A;  2NT2 A;  1Q6N A;  2B3O A;  1YFO A;  1C88 A;  2BIJ A;  1MKP A;  2VTE A;  3ZM2 A;  5I6V A;  1PA1 A;  4QDI A;  4IKC A;  1G7G A;  3OLR A;  3O4S A;  2WJP A;  1GFY A;  2AM1 A;  2OOQ A;  1BZC A;  2VEV A;  2F46 A;  2J17 A;  4OHL A;  1C87 A;  4JMJ A;  1PXH A;  3D44 A;  4GE5 A;  5K9V A;  3EB1 A;  2XPC A;  1GQY A;  1LQF A;  5EHP A;  2DXP A;  3V0E A;  4KYR A;  1KAK A;  3MMJ A;  3O4T A;  2I4G A;  4KI9 A;  4GWF A;  4GRZ A;  1PTV A;  2QBP A;  1G4W R;  5KAD A;  1GQQ A;  2JFG A;  1P31 A;  2HVL A;  5KA2 A;  5M43 A;  3GXG A;  1PTU A;  2QDC A;  1RXD A;  1NO6 A;  1QXK A;  4R0T A;  1Q6S A;  1U25 A;  2NT7 A;  1YPT A;  2F70 A;  3QKP A;  4WOH A;  2I75 A;  2J16 A;  4OHH A;  2BV5 A;  2F6V A;  4NX8 A;  3LJ8 A;  2NZ6 A;  1G7F A;  2Q47 A;  1I9S A;  2IMG A;  5J8R A;  1XRI A;  4CVL A;  2HCM A;  1ZZW A;  2GC6 A;  1PH0 A;  2CM3 A;  2VEU A;  2MBC A;  2OUD A;  2CNE A;  3O5X A;  1T4J A;  2I6J A;  2B49 A;  2YDU A;  2QCJ A;  1P3D A;  2WTZ A;  1OET A;  2G59 A;  3BLT A;  3M4U A;  5K9W A;  3N0A A;  3I80 A;  1L8K A;  1OHD A;  2F6T A;  3AWG A;  2HY3 A;  2QEP A;  4YAA A;  1NZ7 A;  1WAX A;  2CJZ A;  4R0S A;  5K24 A;  1Q6M A;  2M3V A;  4ZIY A;  3I36 A;  2AM2 A;  4UAG A;  3PYZ A;  3O3L A;  4GE2 A;  4RH9 A;  2PI7 A;  2JFF A;  4D3P A;  5KA7 A;  5AWX A;  2H02 A;  4H1O A;  3S3H A;  2I6M A;  1RPM A;  1UAG A;  3S3F A;  4C13 A;  1Q6J A;  3ZMQ A;  1XXV A;  5GTJ A;  3ZM6 A;  4ERC A;  1V3A A;  1YN9 A;  3AWF A;  2I5X A;  3ZM5 A;  1Q6T A;  3MOW A;  2AZR A;  2UUO A;  2I3R A;  3QKQ A;  4HV4 A;  2QBR A;  3QCH A;  2H4V A;  3V0J A;  3RGO A;  3A5K A;  1OEU A;  2CMA A;  5KA4 A;  2BGD A;  1BZJ A;  2HNQ A;  1Q6P A;  1LYV A;  3F9B A;  3QCJ A;  2E0T A;  2GCB A;  3CWE A;  3PS5 A;  1OEM X;  4NWF A;  1C84 A;  1NWE A;  4B04 A;  1ZCK A;  2A8B A;  2G6Z A;  1I57 A;  4WU2 A;  5IBM A;  5KA1 A;  4DGX A;  4CVK A;  1G1G A;  2ZMM A; 
#chains in the Genus database with same CATH homology
 1YWF A;  2NLK A;  4GE6 A;  4PYH A;  2CNH A;  3H2X A;  1VHR A;  2R0B A;  1SUG A;  5MMZ B;  2QBS A;  2I6P A;  3O4U A;  4RDD A;  1ECV A;  1YTS A;  5IBS A;  4OHI A;  4OHE A;  2I6O A;  4H34 A;  2F6F A;  2HNP A;  3V0H A;  2I42 A;  1LAR A;  4QAP A;  2CNF A;  1OES A;  2FJM A;  1PYN A;  3S4E A;  3D1O A;  1G1F A;  1J4X A;  1I9T A;  1X24 A;  3RZ2 A;  1C85 A;  2QBQ A;  4QUM A;  2WGP A;  4GRY A;  2OZ5 A;  4JMK A;  2JJD A;  2PA5 A;  1Q1M A;  3SME A;  4DGP A;  2BGE A;  1M3G A;  3F99 A;  4RI5 A;  5KA9 A;  2VEX A;  5KAA A;  2CFV A;  5K25 A;  1YTN A;  4I8N A;  1YTW A;  4YR8 B;  2BZL A;  1QZ0 A;  2B4S A;  1YGU A;  3MOZ A;  5BX1 A;  1XM2 A;  2HC2 A;  3QCE A;  4D3Q A;  5K22 A;  2PQ5 A;  2Q05 A;  4KYQ A;  4OHD A;  4ZN5 A;  1L8G A;  4QAH A;  2F6W A;  4Y2E A;  2AHS A;  3EZZ A;  3QCG A;  1G1H A;  4MBB A;  4JNB A;  3V0D A;  2I6I A;  4BPC A;  2CM2 A;  1AAX A;  2FH7 A;  3OMH A;  4HJP A;  4ZRT A;  2NTA A;  1WRM A;  5BZZ A;  2F6Y A;  2PBN A;  3EU0 A;  4RH5 A;  2I3U A;  3BLU A;  5EHR A;  2CM7 A;  2ZN7 A;  5KA8 A;  2CMC A;  1OEV A;  1T48 A;  4RHG A;  3QCC A;  3RGQ A;  2ESB A;  4QUN A;  3QCB A;  3BM8 A;  4R30 A;  1EEO A;  1OHE A;  3D1H A;  4NYH A;  4D3R A;  2I4H A;  4HJQ A;  1G4U S;  2H04 A;  1ZCL A;  3B7O A;  4NWG A;  4RKK A;  3S4O A;  2A3K A;  2OC3 A;  2GJT A;  4Y14 A;  3F9A A;  2C7S A;  1OHC A;  3QCD A;  3QCM A;  1GWZ A;  2H4G A;  5BZX A;  1PA9 A;  3ZM1 A;  3ZV2 A;  1JLN A;  2PSZ A;  5K23 A;  1U26 A;  2CNI A;  2HXP A;  1OEO X;  3V0F A;  2I4E A;  3QCN A;  2GP0 A;  4WU3 A;  3I7Z A;  4J51 A;  1XBO A;  3ZM0 A;  1ONZ A;  1A5Y A;  3SR9 A;  2QDM A;  1FPZ A;  3A5J A;  2F71 A;  3QCI A;  2P4D A;  2Y2F A;  1WCH A;  1ZC0 A;  5KAC A;  4GFV A;  1R6H A;  2B4U A;  4NND A;  3RO1 A;  5KA3 A;  1NNY A;  4PVG A;  3CM3 A;  4GS0 A;  4GFU A;  1KAV A;  5KAB A;  1YZ4 A;  3V0G A;  2QCT A;  1U24 A;  1C86 A;  3NME A;  3F81 A;  1D5R A;  3QCL A;  4JBC A;  2CMB A;  2CM8 A;  2P6X A;  3D9C A;  1P15 A;  2I1Y A;  3V0I A;  4ZI4 A;  1T49 A;  2H03 A;  1JF7 A;  2B4P A;  1NL9 A;  4BJO A;  1BZH A;  3D1Q A;  2SHP A;  2RF6 A;  1PTT A;  5HDE A;  1YGR A;  3EAX A;  4QBE A;  2Y96 A;  2B07 A;  2PT0 A;  1C83 A;  3D42 A;  4AZ1 A;  4WTY A;  4TVV A;  3U96 A;  3QCF A;  1FQ1 A;  4S0G A;  2H4K A;  1PTY A;  2C46 A;  3AWE A;  3ZM3 A;  4QBW A;  5LXQ B;  2F6Z A;  3S3E A;  2GWO A;  2NV5 A;  1EEN A;  3F41 A;  3S3K A;  2VEY A;  3GXH A;  4HRF A;  2CNG A;  2QDP A;  2HB1 A;  3ZMP A;  1ONY A;  3QCK A;  1NWL A;  3BRH A;  2VEW A;  4Z6B A;  3EMU A;  4ICZ A;  2HC1 A;  5BUG A;  2J16 B;  1XXP A;  2B4O A;  2FJN A;  4RI4 A;  5KA0 A;  1FPR A;  2NT2 A;  1Q6N A;  2B3O A;  1YFO A;  1C88 A;  2BIJ A;  1MKP A;  3ZM2 A;  5I6V A;  1PA1 A;  4IKC A;  1G7G A;  3OLR A;  3O4S A;  1GFY A;  2OOQ A;  1BZC A;  2VEV A;  2F46 A;  2J17 A;  4OHL A;  1C87 A;  4JMJ A;  1PXH A;  3D44 A;  4GE5 A;  5K9V A;  3EB1 A;  1LQF A;  5EHP A;  2DXP A;  3V0E A;  4KYR A;  1KAK A;  3MMJ A;  3O4T A;  2I4G A;  4KI9 A;  4GWF A;  4GRZ A;  1PTV A;  2QBP A;  1G4W R;  5KAD A;  2HVL A;  5KA2 A;  5M43 A;  3GXG A;  1PTU A;  2QDC A;  1RXD A;  1NO6 A;  1QXK A;  4R0T A;  1Q6S A;  1U25 A;  2NT7 A;  1YPT A;  2F70 A;  3QKP A;  4WOH A;  2I75 A;  2J16 A;  4OHH A;  2BV5 A;  2F6V A;  4NX8 A;  3LJ8 A;  2NZ6 A;  1G7F A;  2Q47 A;  1I9S A;  2IMG A;  5J8R A;  1XRI A;  2HCM A;  1ZZW A;  1PH0 A;  2CM3 A;  2VEU A;  2MBC A;  2OUD A;  2CNE A;  3O5X A;  1T4J A;  2I6J A;  2B49 A;  2YDU A;  2QCJ A;  1OET A;  2G59 A;  3BLT A;  3M4U A;  5K9W A;  3N0A A;  3I80 A;  1L8K A;  1OHD A;  2F6T A;  3AWG A;  2HY3 A;  2QEP A;  4YAA A;  1NZ7 A;  1WAX A;  2CJZ A;  4R0S A;  5K24 A;  1Q6M A;  2M3V A;  3I36 A;  3O3L A;  4GE2 A;  4RH9 A;  2PI7 A;  4D3P A;  5KA7 A;  5AWX A;  2H02 A;  4H1O A;  3S3H A;  2I6M A;  1RPM A;  3S3F A;  1Q6J A;  3ZMQ A;  1XXV A;  5GTJ A;  4ERC A;  1V3A A;  1YN9 A;  3AWF A;  2I5X A;  1Q6T A;  3MOW A;  2AZR A;  2I3R A;  3QKQ A;  2QBR A;  3QCH A;  2H4V A;  3V0J A;  3RGO A;  3A5K A;  1OEU A;  2CMA A;  5KA4 A;  2BGD A;  1BZJ A;  2HNQ A;  1Q6P A;  1LYV A;  3F9B A;  3QCJ A;  2E0T A;  3CWE A;  3PS5 A;  1OEM X;  4NWF A;  1C84 A;  1NWE A;  4B04 A;  1ZCK A;  2A8B A;  2G6Z A;  1I57 A;  4WU2 A;  5IBM A;  5KA1 A;  4DGX A;  1G1G A;  2ZMM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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