2AZRA

Crystal structure of ptp1b with bicyclic thiophene inhibitor
Total Genus 105
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 105
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2azrA00
1PH0A 2HVLA 4R0TA 1Q6NA 2CNGA 1I57A 1P15A 3GXHA 4BJOA 2F6WA 1PTYA 2VEUA 1YN9A 4QBEA 4Y14A 3D1OA 2PA5A 4ZN5A 5EHRA 2QDCA 2H4VA 4KYRA 3I36A 1FPRA 2WGPA 2HC1A 2HC2A 2QBRA 1G1FA 4GE2A 3M4UA 5BUGA 3V0EA 2Q47A 3ZM0A 3LJ8A 1LYVA 1BZCA 1YZ4A 5IBMA 2I75A 4J51A 4WU2A 5K24A 3O3LA 1RPMA 1XRIA 5GTJA 5K22A 3AWGA 1ECVA 2PQ5A 2PT0A 1C88A 2I6OA 1OEVA 2M3VA 1XXPA 4NNDA 1C84A 5K9VA 2QBQA 3GXGA 5KA1A 4D3QA 4WTYA 3S3HA 4ERCA 3NMEA 5KA0A 4Y2EA 4DGPA 2F6FA 1PTVA 5KA2A 1I9SA 1GFYA 2CM7A 2PI7A 3S4EA 3MMJA 3V0FA 3ZM3A 1Q6PA 1NWEA 2J17A 4ZRTA 3O4UA 1C86A 2QEPA 1T49A 1U24A 4WU3A 2CM2A 2FJMA 3I80A 3U96A 2A3KA 2I5XA 4GRYA 1C85A 4NWFA 2NT2A 3QCIA 1SUGA 2YDUA 4IKCA 1U26A 2HB1A 1BZJA 2I42A 2H02A 2B4UA 1G1HA 5K23A 1PXHA 5MMZB 3QCEA 2CNHA 2JJDA 4GWFA 4MBBA 2PBNA 1PTTA 2QBSA 1OEOX 5KA3A 2I6MA 2F6TA 2I6JA 1NWLA 3OMHA 3EAXA 2F6YA 3BLTA 5I6VA 1T48A 1YPTA 3QCJA 3QCFA 1OESA 3QCHA 5EHPA 1G1GA 1L8KA 1OHDA 3V0GA 5KA9A 4OHEA 1QZ0A 1ZCKA 1V3AA 4RKKA 5IBSA 2I6PA 3V0IA 1YWFA 3QCBA 3CWEA 1YGRA 3S4OA 3V0JA 3H2XA 4RI4A 2FJNA 3ZV2A 3F99A 5BX1A 2NV5A 2HCMA 1R6HA 4S0GA 5AWXA 3D44A 3F81A 4RH9A 2ZN7A 4NYHA 1G4US 3SMEA 1G4WR 3QKQA 4RI5A 5KACA 2F70A 1YTWA 4OHIA 2BGDA 2OOQA 1Q6JA 1U25A 3MOWA 3F9AA 1A5YA 2HNQA 2Q05A 2OUDA 1KAVA 3MOZA 2P6XA 2OZ5A 5KA7A 1FPZA 2CMBA 1NO6A 1PYNA 1WRMA 1OHCA 1KAKA 2R0BA 3ZM2A 2HXPA 2ESBA 2HNPA 1ZZWA 2F71A 2CM3A 2BZLA 2I4GA 3CM3A 2B3OA 4JBCA 4JMKA 3B7OA 3I7ZA 4RHGA 4GS0A 3O4SA 1PTUA 3D42A 2NLKA 4YR8B 2P4DA 3QCCA 2A8BA 1J4XA 4OHHA 1WAXA 2C46A 4PYHA 2CMAA 2HY3A 1ONZA 3ZMPA 5HDEA 2CFVA 2GWOA 2F6ZA 3RGQA 2RF6A 1C83A 4HRFA 2IMGA 4Z6BA 3QCNA 3O5XA 4NX8A 2I1YA 3BLUA 2VEYA 2VEXA 5KABA 1NNYA 4AZ1A 3V0DA 2CJZA 3F9BA 2FH7A 4QUMA 5BZZA 2NTAA 3N0AA 1ZC0A 1X24A 4OHLA 4HJPA 1VHRA 2G6ZA 3PS5A 4BPCA 3QCDA 2J16B 3QCGA 3RO1A 1L8GA 4HJQA 1OHEA 4GE6A 4WOHA 1MKPA 1OETA 4RDDA 1NL9A 4KI9A 3EMUA 3S3FA 4GFUA 2CM8A 3OLRA 2BGEA 1D5RA 2I3UA 3QCMA 2CNIA 3RZ2A 2B4SA 4RH5A 3EB1A 2CNEA 3QCKA 4D3PA 5BZXA 4KYQA 5J8RA 3S3KA 2DXPA 4I8NA 2SHPA 5M43A 3BM8A 4R0SA 2QDPA 4QAHA 1YFOA 1BZHA 1ZCLA 3O4TA 1G7GA 1YTNA 2H4KA 3EZZA 1YTSA 1AAXA 2OC3A 2B49A 5KA4A 1NZ7A 1OEUA 1QXKA 2H03A 4OHDA 2J16A 1WCHA 4YAAA 1XXVA 2B4OA 2CNFA 5KA8A 4QAPA 2MBCA 2VEVA 2QCJA 4H1OA 4R30A 1XM2A 3F41A 4ZI4A 1M3GA 4GFVA 1ONYA 2GP0A 2QCTA 1JF7A 4QBWA 4B04A 4JMJA 2C7SA 2E0TA 3D1HA 2BV5A 2H4GA 4NWGA 1T4JA 4TVVA 1OEMX 3A5JA 2G59A 1Q6MA 1LQFA 1Q1MA 4QUNA 2NZ6A 3AWEA 2ZMMA 5KADA 4ICZA 1XBOA 1I9TA 4DGXA 4GE5A 1Q6TA 3BRHA 1EEOA 1G7FA 2AZRA 4H34A 2GJTA 1FQ1A 3QCLA 5K9WA 1EENA 3S3EA 2I6IA 1JLNA 2QDMA 5LXQB 3A5KA 1C87A 2Y2FA 3SR9A 3AWFA 3D9CA 1Q6SA 2B07A 2I4EA 1PA1A 1RXDA 2I3RA 2QBPA 1LARA 2F46A 4GRZA 3ZMQA 2CMCA 2I4HA 5K25A 2BIJA 2PSZA 2Y96A 3ZM1A 2H04A 3QKPA 1GWZA 4D3RA 3RGOA 4PVGA 5KAAA 3V0HA 2AHSA 3EU0A 4JNBA 2B4PA 1PA9A 2F6VA 2VEWA 1YGUA 3D1QA 2NT7A
chains in the Genus database with same CATH superfamily
1PH0A 2HVLA 2XJAA 4R0TA 1Q6NA 2CNGA 1I57A 1P15A 3GXHA 4BJOA 2F6WA 1PTYA 2VEUA 1YN9A 4QBEA 4Y14A 3D1OA 2PA5A 4ZN5A 5EHRA 2QDCA 2H4VA 4KYRA 4HV4A 3I36A 4C13A 2JFGA 1FPRA 2WGPA 2HC1A 1JBVA 2HC2A 3MVNA 2QBRA 1G1FA 3HN7A 4GE2A 4ZIYA 3M4UA 5BUGA 3V0EA 2Q47A 3ZM6A 3ZM0A 3LJ8A 1LYVA 1BZCA 1YZ4A 5IBMA 2I75A 2GCAA 4J51A 4WU2A 5K24A 3O3LA 1RPMA 1XRIA 5GTJA 5K22A 3AWGA 1ECVA 2PQ5A 2PT0A 1C88A 2I6OA 1OEVA 2M3VA 1XXPA 4NNDA 1C84A 5K9VA 2QBQA 3GXGA 2VTEA 5KA1A 4D3QA 4WTYA 3S3HA 4ERCA 3NMEA 5KA0A 4Y2EA 2Y66A 2F6FA 1PTVA 5KA2A 4DGPA 1I9SA 1GFYA 2XPCA 1E8CA 2CM7A 2PI7A 3S4EA 3MMJA 3V0FA 3ZM3A 1Q6PA 1NWEA 2X5OA 2J17A 4ZRTA 3O4UA 1C86A 2GC6A 2QEPA 1T49A 1U24A 3NRSA 4WU3A 2CM2A 2FJMA 3I80A 3U96A 4CVKA 2A3KA 2VORA 2VTDA 2I5XA 2Y67A 4GRYA 1C85A 4NWFA 2NT2A 3QCIA 1SUGA 2YDUA 2AM2A 4IKCA 1U26A 2HB1A 1BZJA 2GC5A 2I42A 4C12A 2H02A 2B4UA 1G1HA 5K23A 1PXHA 5MMZB 3QCEA 2CNHA 2JJDA 4GWFA 4MBBA 1P31A 2PBNA 3QCZA 1PTTA 2QBSA 1OEOX 5KA3A 2I6MA 2F6TA 2I6JA 1NWLA 3OMHA 3EAXA 2F6YA 3BLTA 5I6VA 1T48A 1YPTA 3QCJA 3QCFA 1OESA 3QCHA 5EHPA 1G1GA 1L8KA 1OHDA 3V0GA 5KA9A 4OHEA 1QZ0A 1ZCKA 1V3AA 1GG4A 4RKKA 5IBSA 2I6PA 3V0IA 1YWFA 3QCBA 3CWEA 1YGRA 3S4OA 3V0JA 3H2XA 4RI4A 4UAGA 2FJNA 3ZV2A 3F99A 5BX1A 2NV5A 2HCMA 1R6HA 4S0GA 4QF5A 5AWXA 3D44A 3F81A 4RH9A 2ZN7A 4NYHA 4CVLA 1G4US 3SMEA 1G4WR 3QKQA 4RI5A 2WTZA 5KACA 2F70A 1YTWA 4OHIA 2BGDA 2OOQA 1Q6JA 1U25A 3MOWA 2VOSA 3F9AA 1A5YA 2HNQA 2Q05A 2OUDA 1KAVA 3MOZA 3UAGA 2P6XA 3LK7A 2OZ5A 5KA7A 1FPZA 2CMBA 1NO6A 1PYNA 1WRMA 1OHCA 1KAKA 2R0BA 3ZM2A 2JFHA 2HXPA 2ESBA 2HNPA 1ZZWA 2F71A 2CM3A 2BZLA 2GCBA 2I4GA 3CM3A 2B3OA 3N2AA 4JBCA 4JMKA 3B7OA 3I7ZA 2UUPA 4RHGA 4CVMA 4GS0A 1W78A 1W7KA 3O4SA 1PTUA 3D42A 2NLKA 3PYZA 2F00A 4YR8B 2P4DA 3QCCA 1E0DA 2A8BA 1J4XA 4OHHA 1WAXA 2C46A 4BUBA 4PYHA 2CMAA 2HY3A 1ONZA 2UAGA 3ZMPA 5HDEA 2CFVA 2GWOA 2F6ZA 3RGQA 2RF6A 1C83A 4HRFA 2IMGA 4Z6BA 3ZL8A 3QCNA 3O5XA 4NX8A 2I1YA 3BLUA 2VEYA 2VEXA 1GQYA 2WJPA 5KABA 1NNYA 4AZ1A 3V0DA 4QDIA 2CJZA 3F9BA 2FH7A 5A5FA 4QUMA 5BZZA 2NTAA 3N0AA 1ZC0A 1X24A 4OHLA 4HJPA 1VHRA 2G6ZA 3PS5A 4BPCA 3QCDA 2J16B 3QCGA 3RO1A 1L8GA 4HJQA 1OHEA 4GE6A 4WOHA 1MKPA 1OETA 4RDDA 1FGSA 1NL9A 4KI9A 3EMUA 3S3FA 4GFUA 2CM8A 3OLRA 2BGEA 1P3DA 1D5RA 2I3UA 3QCMA 2CNIA 3ZM5A 3RZ2A 2B4SA 1J6UA 4RH5A 3EB1A 2CNEA 3QCKA 4D3PA 5BZXA 4KYQA 5J8RA 3S3KA 2DXPA 4I8NA 1UAGA 2SHPA 5M43A 3BM8A 4R0SA 2QDPA 4QAHA 1YFOA 1BZHA 4BUCA 1ZCLA 3O4TA 1G7GA 1YTNA 2H4KA 2Y1OA 3EZZA 1YTSA 1AAXA 2OC3A 2B49A 5KA4A 1NZ7A 1OEUA 1QXKA 2H03A 4OHDA 2J16A 1WCHA 4YAAA 1XXVA 2B4OA 2CNFA 5KA8A 4QAPA 2MBCA 2VEVA 2QCJA 4H1OA 4R30A 1XM2A 3F41A 4ZI4A 1M3GA 4GFVA 1ONYA 2GP0A 2QCTA 1JF7A 1GQQA 4QBWA 4B04A 4JMJA 2C7SA 2E0TA 3D1HA 2BV5A 2H4GA 4NWGA 1T4JA 4TVVA 1OEMX 3A5JA 2G59A 1Q6MA 1LQFA 1Q1MA 4QUNA 2NZ6A 1JBWA 3AWEA 2ZMMA 5KADA 4ICZA 1XBOA 1I9TA 4DGXA 4GE5A 2AM1A 1Q6TA 3BRHA 1EEOA 1G7FA 2AZRA 4H34A 2GJTA 1FQ1A 3QCLA 5K9WA 1EENA 3S3EA 2I6IA 1JLNA 2QDMA 5LXQB 3A5KA 1C87A 2Y2FA 2Y68A 3SR9A 5A5EA 3AWFA 3D9CA 1EEHA 1Q6SA 2B07A 2I4EA 1PA1A 1RXDA 2I3RA 2QBPA 1LARA 2F46A 4GRZA 3ZMQA 2CMCA 2I4HA 5K25A 2BIJA 2UUOA 2PSZA 2Y96A 3ZM1A 2H04A 3QKPA 1GWZA 4D3RA 3RGOA 4PVGA 2JFFA 5KAAA 1O5ZA 3V0HA 2AHSA 3EU0A 4JNBA 2B4PA 1PA9A 2F6VA 2VEWA 1YGUA 3D1QA 2NT7A
chains in the Genus database with same CATH topology
1PH0A 2HVLA 4R0TA 1Q6NA 2CNGA 1I57A 1P15A 3GXHA 4BJOA 2F6WA 1PTYA 2VEUA 1YN9A 4QBEA 4Y14A 3D1OA 2PA5A 4ZN5A 5EHRA 2QDCA 2H4VA 4KYRA 3I36A 1FPRA 2WGPA 2HC1A 2HC2A 2QBRA 1G1FA 4GE2A 3M4UA 5BUGA 3V0EA 2Q47A 3ZM0A 3LJ8A 1LYVA 1BZCA 1YZ4A 5IBMA 2I75A 4J51A 4WU2A 5K24A 3O3LA 1RPMA 1XRIA 5GTJA 5K22A 3AWGA 1ECVA 2PQ5A 2PT0A 1C88A 2I6OA 1OEVA 2M3VA 1XXPA 4NNDA 1C84A 5K9VA 2QBQA 3GXGA 5KA1A 4D3QA 4WTYA 3S3HA 4ERCA 3NMEA 5KA0A 4Y2EA 4DGPA 2F6FA 1PTVA 5KA2A 1I9SA 1GFYA 2CM7A 2PI7A 3S4EA 3MMJA 3V0FA 3ZM3A 1Q6PA 1NWEA 2J17A 4ZRTA 3O4UA 1C86A 2QEPA 1T49A 1U24A 4WU3A 2CM2A 2FJMA 3I80A 3U96A 2A3KA 2I5XA 4GRYA 1C85A 4NWFA 2NT2A 3QCIA 1SUGA 2YDUA 4IKCA 1U26A 2HB1A 1BZJA 2I42A 2H02A 2B4UA 1G1HA 5K23A 1PXHA 5MMZB 3QCEA 2CNHA 2JJDA 4GWFA 4MBBA 2PBNA 1PTTA 2QBSA 1OEOX 5KA3A 2I6MA 2F6TA 2I6JA 1NWLA 3OMHA 3EAXA 2F6YA 3BLTA 5I6VA 1T48A 1YPTA 3QCJA 3QCFA 1OESA 3QCHA 5EHPA 1G1GA 1L8KA 1OHDA 3V0GA 5KA9A 4OHEA 1QZ0A 1ZCKA 1V3AA 4RKKA 5IBSA 2I6PA 3V0IA 1YWFA 3QCBA 3CWEA 1YGRA 3S4OA 3V0JA 3H2XA 4RI4A 2FJNA 3ZV2A 3F99A 5BX1A 2NV5A 2HCMA 1R6HA 4S0GA 5AWXA 3D44A 3F81A 4RH9A 2ZN7A 4NYHA 1G4US 3SMEA 1G4WR 3QKQA 4RI5A 5KACA 2F70A 1YTWA 4OHIA 2BGDA 2OOQA 1Q6JA 1U25A 3MOWA 3F9AA 1A5YA 2HNQA 2Q05A 2OUDA 1KAVA 3MOZA 2P6XA 2OZ5A 5KA7A 1FPZA 2CMBA 1NO6A 1PYNA 1WRMA 1OHCA 1KAKA 2R0BA 3ZM2A 2HXPA 2ESBA 2HNPA 1ZZWA 2F71A 2CM3A 2BZLA 2I4GA 3CM3A 2B3OA 4JBCA 4JMKA 3B7OA 3I7ZA 4RHGA 4GS0A 3O4SA 1PTUA 3D42A 2NLKA 4YR8B 2P4DA 3QCCA 2A8BA 1J4XA 4OHHA 1WAXA 2C46A 4PYHA 2CMAA 2HY3A 1ONZA 3ZMPA 5HDEA 2CFVA 2GWOA 2F6ZA 3RGQA 2RF6A 1C83A 4HRFA 2IMGA 4Z6BA 3QCNA 3O5XA 4NX8A 2I1YA 3BLUA 2VEYA 2VEXA 5KABA 1NNYA 4AZ1A 3V0DA 2CJZA 3F9BA 2FH7A 4QUMA 5BZZA 2NTAA 3N0AA 1ZC0A 1X24A 4OHLA 4HJPA 1VHRA 2G6ZA 3PS5A 4BPCA 3QCDA 2J16B 3QCGA 3RO1A 1L8GA 4HJQA 1OHEA 4GE6A 4WOHA 1MKPA 1OETA 4RDDA 1NL9A 4KI9A 3EMUA 3S3FA 4GFUA 2CM8A 3OLRA 2BGEA 1D5RA 2I3UA 3QCMA 2CNIA 3RZ2A 2B4SA 4RH5A 3EB1A 2CNEA 3QCKA 4D3PA 5BZXA 4KYQA 5J8RA 3S3KA 2DXPA 4I8NA 2SHPA 5M43A 3BM8A 4R0SA 2QDPA 4QAHA 1YFOA 1BZHA 1ZCLA 3O4TA 1G7GA 1YTNA 2H4KA 3EZZA 1YTSA 1AAXA 2OC3A 2B49A 5KA4A 1NZ7A 1OEUA 1QXKA 2H03A 4OHDA 2J16A 1WCHA 4YAAA 1XXVA 2B4OA 2CNFA 5KA8A 4QAPA 2MBCA 2VEVA 2QCJA 4H1OA 4R30A 1XM2A 3F41A 4ZI4A 1M3GA 4GFVA 1ONYA 2GP0A 2QCTA 1JF7A 4QBWA 4B04A 4JMJA 2C7SA 2E0TA 3D1HA 2BV5A 2H4GA 4NWGA 1T4JA 4TVVA 1OEMX 3A5JA 2G59A 1Q6MA 1LQFA 1Q1MA 4QUNA 2NZ6A 3AWEA 2ZMMA 5KADA 4ICZA 1XBOA 1I9TA 4DGXA 4GE5A 1Q6TA 3BRHA 1EEOA 1G7FA 2AZRA 4H34A 2GJTA 1FQ1A 3QCLA 5K9WA 1EENA 3S3EA 2I6IA 1JLNA 2QDMA 5LXQB 3A5KA 1C87A 2Y2FA 3SR9A 3AWFA 3D9CA 1Q6SA 2B07A 2I4EA 1PA1A 1RXDA 2I3RA 2QBPA 1LARA 2F46A 4GRZA 3ZMQA 2CMCA 2I4HA 5K25A 2BIJA 2PSZA 2Y96A 3ZM1A 2H04A 3QKPA 1GWZA 4D3RA 3RGOA 4PVGA 5KAAA 3V0HA 2AHSA 3EU0A 4JNBA 2B4PA 1PA9A 2F6VA 2VEWA 1YGUA 3D1QA 2NT7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PH0 A;  2HVL A;  4R0T A;  1Q6N A;  2CNG A;  1I57 A;  1P15 A;  3GXH A;  4BJO A;  2F6W A;  1PTY A;  2VEU A;  1YN9 A;  4QBE A;  4Y14 A;  3D1O A;  2PA5 A;  4ZN5 A;  5EHR A;  2QDC A;  2H4V A;  4KYR A;  3I36 A;  1FPR A;  2WGP A;  2HC1 A;  2HC2 A;  2QBR A;  1G1F A;  4GE2 A;  3M4U A;  5BUG A;  3V0E A;  2Q47 A;  3ZM0 A;  3LJ8 A;  1LYV A;  1BZC A;  1YZ4 A;  5IBM A;  2I75 A;  4J51 A;  4WU2 A;  5K24 A;  3O3L A;  1RPM A;  1XRI A;  5GTJ A;  5K22 A;  3AWG A;  1ECV A;  2PQ5 A;  2PT0 A;  1C88 A;  2I6O A;  1OEV A;  2M3V A;  1XXP A;  4NND A;  1C84 A;  5K9V A;  2QBQ A;  3GXG A;  5KA1 A;  4D3Q A;  4WTY A;  3S3H A;  4ERC A;  3NME A;  5KA0 A;  4Y2E A;  4DGP A;  2F6F A;  1PTV A;  5KA2 A;  1I9S A;  1GFY A;  2CM7 A;  2PI7 A;  3S4E A;  3MMJ A;  3V0F A;  3ZM3 A;  1Q6P A;  1NWE A;  2J17 A;  4ZRT A;  3O4U A;  1C86 A;  2QEP A;  1T49 A;  1U24 A;  4WU3 A;  2CM2 A;  2FJM A;  3I80 A;  3U96 A;  2A3K A;  2I5X A;  4GRY A;  1C85 A;  4NWF A;  2NT2 A;  3QCI A;  1SUG A;  2YDU A;  4IKC A;  1U26 A;  2HB1 A;  1BZJ A;  2I42 A;  2H02 A;  2B4U A;  1G1H A;  5K23 A;  1PXH A;  5MMZ B;  3QCE A;  2CNH A;  2JJD A;  4GWF A;  4MBB A;  2PBN A;  1PTT A;  2QBS A;  1OEO X;  5KA3 A;  2I6M A;  2F6T A;  2I6J A;  1NWL A;  3OMH A;  3EAX A;  2F6Y A;  3BLT A;  5I6V A;  1T48 A;  1YPT A;  3QCJ A;  3QCF A;  1OES A;  3QCH A;  5EHP A;  1G1G A;  1L8K A;  1OHD A;  3V0G A;  5KA9 A;  4OHE A;  1QZ0 A;  1ZCK A;  1V3A A;  4RKK A;  5IBS A;  2I6P A;  3V0I A;  1YWF A;  3QCB A;  3CWE A;  1YGR A;  3S4O A;  3V0J A;  3H2X A;  4RI4 A;  2FJN A;  3ZV2 A;  3F99 A;  5BX1 A;  2NV5 A;  2HCM A;  1R6H A;  4S0G A;  5AWX A;  3D44 A;  3F81 A;  4RH9 A;  2ZN7 A;  4NYH A;  1G4U S;  3SME A;  1G4W R;  3QKQ A;  4RI5 A;  5KAC A;  2F70 A;  1YTW A;  4OHI A;  2BGD A;  2OOQ A;  1Q6J A;  1U25 A;  3MOW A;  3F9A A;  1A5Y A;  2HNQ A;  2Q05 A;  2OUD A;  1KAV A;  3MOZ A;  2P6X A;  2OZ5 A;  5KA7 A;  1FPZ A;  2CMB A;  1NO6 A;  1PYN A;  1WRM A;  1OHC A;  1KAK A;  2R0B A;  3ZM2 A;  2HXP A;  2ESB A;  2HNP A;  1ZZW A;  2F71 A;  2CM3 A;  2BZL A;  2I4G A;  3CM3 A;  2B3O A;  4JBC A;  4JMK A;  3B7O A;  3I7Z A;  4RHG A;  4GS0 A;  3O4S A;  1PTU A;  3D42 A;  2NLK A;  4YR8 B;  2P4D A;  3QCC A;  2A8B A;  1J4X A;  4OHH A;  1WAX A;  2C46 A;  4PYH A;  2CMA A;  2HY3 A;  1ONZ A;  3ZMP A;  5HDE A;  2CFV A;  2GWO A;  2F6Z A;  3RGQ A;  2RF6 A;  1C83 A;  4HRF A;  2IMG A;  4Z6B A;  3QCN A;  3O5X A;  4NX8 A;  2I1Y A;  3BLU A;  2VEY A;  2VEX A;  5KAB A;  1NNY A;  4AZ1 A;  3V0D A;  2CJZ A;  3F9B A;  2FH7 A;  4QUM A;  5BZZ A;  2NTA A;  3N0A A;  1ZC0 A;  1X24 A;  4OHL A;  4HJP A;  1VHR A;  2G6Z A;  3PS5 A;  4BPC A;  3QCD A;  2J16 B;  3QCG A;  3RO1 A;  1L8G A;  4HJQ A;  1OHE A;  4GE6 A;  4WOH A;  1MKP A;  1OET A;  4RDD A;  1NL9 A;  4KI9 A;  3EMU A;  3S3F A;  4GFU A;  2CM8 A;  3OLR A;  2BGE A;  1D5R A;  2I3U A;  3QCM A;  2CNI A;  3RZ2 A;  2B4S A;  4RH5 A;  3EB1 A;  2CNE A;  3QCK A;  4D3P A;  5BZX A;  4KYQ A;  5J8R A;  3S3K A;  2DXP A;  4I8N A;  2SHP A;  5M43 A;  3BM8 A;  4R0S A;  2QDP A;  4QAH A;  1YFO A;  1BZH A;  1ZCL A;  3O4T A;  1G7G A;  1YTN A;  2H4K A;  3EZZ A;  1YTS A;  1AAX A;  2OC3 A;  2B49 A;  5KA4 A;  1NZ7 A;  1OEU A;  1QXK A;  2H03 A;  4OHD A;  2J16 A;  1WCH A;  4YAA A;  1XXV A;  2B4O A;  2CNF A;  5KA8 A;  4QAP A;  2MBC A;  2VEV A;  2QCJ A;  4H1O A;  4R30 A;  1XM2 A;  3F41 A;  4ZI4 A;  1M3G A;  4GFV A;  1ONY A;  2GP0 A;  2QCT A;  1JF7 A;  4QBW A;  4B04 A;  4JMJ A;  2C7S A;  2E0T A;  3D1H A;  2BV5 A;  2H4G A;  4NWG A;  1T4J A;  4TVV A;  1OEM X;  3A5J A;  2G59 A;  1Q6M A;  1LQF A;  1Q1M A;  4QUN A;  2NZ6 A;  3AWE A;  2ZMM A;  5KAD A;  4ICZ A;  1XBO A;  1I9T A;  4DGX A;  4GE5 A;  1Q6T A;  3BRH A;  1EEO A;  1G7F A;  2AZR A;  4H34 A;  2GJT A;  1FQ1 A;  3QCL A;  5K9W A;  1EEN A;  3S3E A;  2I6I A;  1JLN A;  2QDM A;  5LXQ B;  3A5K A;  1C87 A;  2Y2F A;  3SR9 A;  3AWF A;  3D9C A;  1Q6S A;  2B07 A;  2I4E A;  1PA1 A;  1RXD A;  2I3R A;  2QBP A;  1LAR A;  2F46 A;  4GRZ A;  3ZMQ A;  2CMC A;  2I4H A;  5K25 A;  2BIJ A;  2PSZ A;  2Y96 A;  3ZM1 A;  2H04 A;  3QKP A;  1GWZ A;  4D3R A;  3RGO A;  4PVG A;  5KAA A;  3V0H A;  2AHS A;  3EU0 A;  4JNB A;  2B4P A;  1PA9 A;  2F6V A;  2VEW A;  1YGU A;  3D1Q A;  2NT7 A; 
#chains in the Genus database with same CATH topology
 1PH0 A;  2HVL A;  2XJA A;  4R0T A;  1Q6N A;  2CNG A;  1I57 A;  1P15 A;  3GXH A;  4BJO A;  2F6W A;  1PTY A;  2VEU A;  1YN9 A;  4QBE A;  4Y14 A;  3D1O A;  2PA5 A;  4ZN5 A;  5EHR A;  2QDC A;  2H4V A;  4KYR A;  4HV4 A;  3I36 A;  4C13 A;  2JFG A;  1FPR A;  2WGP A;  2HC1 A;  1JBV A;  2HC2 A;  3MVN A;  2QBR A;  1G1F A;  3HN7 A;  4GE2 A;  4ZIY A;  3M4U A;  5BUG A;  3V0E A;  2Q47 A;  3ZM6 A;  3ZM0 A;  3LJ8 A;  1LYV A;  1BZC A;  1YZ4 A;  5IBM A;  2I75 A;  2GCA A;  4J51 A;  4WU2 A;  5K24 A;  3O3L A;  1RPM A;  1XRI A;  5GTJ A;  5K22 A;  3AWG A;  1ECV A;  2PQ5 A;  2PT0 A;  1C88 A;  2I6O A;  1OEV A;  2M3V A;  1XXP A;  4NND A;  1C84 A;  5K9V A;  2QBQ A;  3GXG A;  2VTE A;  5KA1 A;  4D3Q A;  4WTY A;  3S3H A;  4ERC A;  3NME A;  5KA0 A;  4Y2E A;  2Y66 A;  2F6F A;  1PTV A;  5KA2 A;  4DGP A;  1I9S A;  1GFY A;  2XPC A;  1E8C A;  2CM7 A;  2PI7 A;  3S4E A;  3MMJ A;  3V0F A;  3ZM3 A;  1Q6P A;  1NWE A;  2X5O A;  2J17 A;  4ZRT A;  3O4U A;  1C86 A;  2GC6 A;  2QEP A;  1T49 A;  1U24 A;  3NRS A;  4WU3 A;  2CM2 A;  2FJM A;  3I80 A;  3U96 A;  4CVK A;  2A3K A;  2VOR A;  2VTD A;  2I5X A;  2Y67 A;  4GRY A;  1C85 A;  4NWF A;  2NT2 A;  3QCI A;  1SUG A;  2YDU A;  2AM2 A;  4IKC A;  1U26 A;  2HB1 A;  1BZJ A;  2GC5 A;  2I42 A;  4C12 A;  2H02 A;  2B4U A;  1G1H A;  5K23 A;  1PXH A;  5MMZ B;  3QCE A;  2CNH A;  2JJD A;  4GWF A;  4MBB A;  1P31 A;  2PBN A;  3QCZ A;  1PTT A;  2QBS A;  1OEO X;  5KA3 A;  2I6M A;  2F6T A;  2I6J A;  1NWL A;  3OMH A;  3EAX A;  2F6Y A;  3BLT A;  5I6V A;  1T48 A;  1YPT A;  3QCJ A;  3QCF A;  1OES A;  3QCH A;  5EHP A;  1G1G A;  1L8K A;  1OHD A;  3V0G A;  5KA9 A;  4OHE A;  1QZ0 A;  1ZCK A;  1V3A A;  1GG4 A;  4RKK A;  5IBS A;  2I6P A;  3V0I A;  1YWF A;  3QCB A;  3CWE A;  1YGR A;  3S4O A;  3V0J A;  3H2X A;  4RI4 A;  4UAG A;  2FJN A;  3ZV2 A;  3F99 A;  5BX1 A;  2NV5 A;  2HCM A;  1R6H A;  4S0G A;  4QF5 A;  5AWX A;  3D44 A;  3F81 A;  4RH9 A;  2ZN7 A;  4NYH A;  4CVL A;  1G4U S;  3SME A;  1G4W R;  3QKQ A;  4RI5 A;  2WTZ A;  5KAC A;  2F70 A;  1YTW A;  4OHI A;  2BGD A;  2OOQ A;  1Q6J A;  1U25 A;  3MOW A;  2VOS A;  3F9A A;  1A5Y A;  2HNQ A;  2Q05 A;  2OUD A;  1KAV A;  3MOZ A;  3UAG A;  2P6X A;  3LK7 A;  2OZ5 A;  5KA7 A;  1FPZ A;  2CMB A;  1NO6 A;  1PYN A;  1WRM A;  1OHC A;  1KAK A;  2R0B A;  3ZM2 A;  2JFH A;  2HXP A;  2ESB A;  2HNP A;  1ZZW A;  2F71 A;  2CM3 A;  2BZL A;  2GCB A;  2I4G A;  3CM3 A;  2B3O A;  3N2A A;  4JBC A;  4JMK A;  3B7O A;  3I7Z A;  2UUP A;  4RHG A;  4CVM A;  4GS0 A;  1W78 A;  1W7K A;  3O4S A;  1PTU A;  3D42 A;  2NLK A;  3PYZ A;  2F00 A;  4YR8 B;  2P4D A;  3QCC A;  1E0D A;  2A8B A;  1J4X A;  4OHH A;  1WAX A;  2C46 A;  4BUB A;  4PYH A;  2CMA A;  2HY3 A;  1ONZ A;  2UAG A;  3ZMP A;  5HDE A;  2CFV A;  2GWO A;  2F6Z A;  3RGQ A;  2RF6 A;  1C83 A;  4HRF A;  2IMG A;  4Z6B A;  3ZL8 A;  3QCN A;  3O5X A;  4NX8 A;  2I1Y A;  3BLU A;  2VEY A;  2VEX A;  1GQY A;  2WJP A;  5KAB A;  1NNY A;  4AZ1 A;  3V0D A;  4QDI A;  2CJZ A;  3F9B A;  2FH7 A;  5A5F A;  4QUM A;  5BZZ A;  2NTA A;  3N0A A;  1ZC0 A;  1X24 A;  4OHL A;  4HJP A;  1VHR A;  2G6Z A;  3PS5 A;  4BPC A;  3QCD A;  2J16 B;  3QCG A;  3RO1 A;  1L8G A;  4HJQ A;  1OHE A;  4GE6 A;  4WOH A;  1MKP A;  1OET A;  4RDD A;  1FGS A;  1NL9 A;  4KI9 A;  3EMU A;  3S3F A;  4GFU A;  2CM8 A;  3OLR A;  2BGE A;  1P3D A;  1D5R A;  2I3U A;  3QCM A;  2CNI A;  3ZM5 A;  3RZ2 A;  2B4S A;  1J6U A;  4RH5 A;  3EB1 A;  2CNE A;  3QCK A;  4D3P A;  5BZX A;  4KYQ A;  5J8R A;  3S3K A;  2DXP A;  4I8N A;  1UAG A;  2SHP A;  5M43 A;  3BM8 A;  4R0S A;  2QDP A;  4QAH A;  1YFO A;  1BZH A;  4BUC A;  1ZCL A;  3O4T A;  1G7G A;  1YTN A;  2H4K A;  2Y1O A;  3EZZ A;  1YTS A;  1AAX A;  2OC3 A;  2B49 A;  5KA4 A;  1NZ7 A;  1OEU A;  1QXK A;  2H03 A;  4OHD A;  2J16 A;  1WCH A;  4YAA A;  1XXV A;  2B4O A;  2CNF A;  5KA8 A;  4QAP A;  2MBC A;  2VEV A;  2QCJ A;  4H1O A;  4R30 A;  1XM2 A;  3F41 A;  4ZI4 A;  1M3G A;  4GFV A;  1ONY A;  2GP0 A;  2QCT A;  1JF7 A;  1GQQ A;  4QBW A;  4B04 A;  4JMJ A;  2C7S A;  2E0T A;  3D1H A;  2BV5 A;  2H4G A;  4NWG A;  1T4J A;  4TVV A;  1OEM X;  3A5J A;  2G59 A;  1Q6M A;  1LQF A;  1Q1M A;  4QUN A;  2NZ6 A;  1JBW A;  3AWE A;  2ZMM A;  5KAD A;  4ICZ A;  1XBO A;  1I9T A;  4DGX A;  4GE5 A;  2AM1 A;  1Q6T A;  3BRH A;  1EEO A;  1G7F A;  2AZR A;  4H34 A;  2GJT A;  1FQ1 A;  3QCL A;  5K9W A;  1EEN A;  3S3E A;  2I6I A;  1JLN A;  2QDM A;  5LXQ B;  3A5K A;  1C87 A;  2Y2F A;  2Y68 A;  3SR9 A;  5A5E A;  3AWF A;  3D9C A;  1EEH A;  1Q6S A;  2B07 A;  2I4E A;  1PA1 A;  1RXD A;  2I3R A;  2QBP A;  1LAR A;  2F46 A;  4GRZ A;  3ZMQ A;  2CMC A;  2I4H A;  5K25 A;  2BIJ A;  2UUO A;  2PSZ A;  2Y96 A;  3ZM1 A;  2H04 A;  3QKP A;  1GWZ A;  4D3R A;  3RGO A;  4PVG A;  2JFF A;  5KAA A;  1O5Z A;  3V0H A;  2AHS A;  3EU0 A;  4JNB A;  2B4P A;  1PA9 A;  2F6V A;  2VEW A;  1YGU A;  3D1Q A;  2NT7 A; 
#chains in the Genus database with same CATH homology
 1PH0 A;  2HVL A;  4R0T A;  1Q6N A;  2CNG A;  1I57 A;  1P15 A;  3GXH A;  4BJO A;  2F6W A;  1PTY A;  2VEU A;  1YN9 A;  4QBE A;  4Y14 A;  3D1O A;  2PA5 A;  4ZN5 A;  5EHR A;  2QDC A;  2H4V A;  4KYR A;  3I36 A;  1FPR A;  2WGP A;  2HC1 A;  2HC2 A;  2QBR A;  1G1F A;  4GE2 A;  3M4U A;  5BUG A;  3V0E A;  2Q47 A;  3ZM0 A;  3LJ8 A;  1LYV A;  1BZC A;  1YZ4 A;  5IBM A;  2I75 A;  4J51 A;  4WU2 A;  5K24 A;  3O3L A;  1RPM A;  1XRI A;  5GTJ A;  5K22 A;  3AWG A;  1ECV A;  2PQ5 A;  2PT0 A;  1C88 A;  2I6O A;  1OEV A;  2M3V A;  1XXP A;  4NND A;  1C84 A;  5K9V A;  2QBQ A;  3GXG A;  5KA1 A;  4D3Q A;  4WTY A;  3S3H A;  4ERC A;  3NME A;  5KA0 A;  4Y2E A;  4DGP A;  2F6F A;  1PTV A;  5KA2 A;  1I9S A;  1GFY A;  2CM7 A;  2PI7 A;  3S4E A;  3MMJ A;  3V0F A;  3ZM3 A;  1Q6P A;  1NWE A;  2J17 A;  4ZRT A;  3O4U A;  1C86 A;  2QEP A;  1T49 A;  1U24 A;  4WU3 A;  2CM2 A;  2FJM A;  3I80 A;  3U96 A;  2A3K A;  2I5X A;  4GRY A;  1C85 A;  4NWF A;  2NT2 A;  3QCI A;  1SUG A;  2YDU A;  4IKC A;  1U26 A;  2HB1 A;  1BZJ A;  2I42 A;  2H02 A;  2B4U A;  1G1H A;  5K23 A;  1PXH A;  5MMZ B;  3QCE A;  2CNH A;  2JJD A;  4GWF A;  4MBB A;  2PBN A;  1PTT A;  2QBS A;  1OEO X;  5KA3 A;  2I6M A;  2F6T A;  2I6J A;  1NWL A;  3OMH A;  3EAX A;  2F6Y A;  3BLT A;  5I6V A;  1T48 A;  1YPT A;  3QCJ A;  3QCF A;  1OES A;  3QCH A;  5EHP A;  1G1G A;  1L8K A;  1OHD A;  3V0G A;  5KA9 A;  4OHE A;  1QZ0 A;  1ZCK A;  1V3A A;  4RKK A;  5IBS A;  2I6P A;  3V0I A;  1YWF A;  3QCB A;  3CWE A;  1YGR A;  3S4O A;  3V0J A;  3H2X A;  4RI4 A;  2FJN A;  3ZV2 A;  3F99 A;  5BX1 A;  2NV5 A;  2HCM A;  1R6H A;  4S0G A;  5AWX A;  3D44 A;  3F81 A;  4RH9 A;  2ZN7 A;  4NYH A;  1G4U S;  3SME A;  1G4W R;  3QKQ A;  4RI5 A;  5KAC A;  2F70 A;  1YTW A;  4OHI A;  2BGD A;  2OOQ A;  1Q6J A;  1U25 A;  3MOW A;  3F9A A;  1A5Y A;  2HNQ A;  2Q05 A;  2OUD A;  1KAV A;  3MOZ A;  2P6X A;  2OZ5 A;  5KA7 A;  1FPZ A;  2CMB A;  1NO6 A;  1PYN A;  1WRM A;  1OHC A;  1KAK A;  2R0B A;  3ZM2 A;  2HXP A;  2ESB A;  2HNP A;  1ZZW A;  2F71 A;  2CM3 A;  2BZL A;  2I4G A;  3CM3 A;  2B3O A;  4JBC A;  4JMK A;  3B7O A;  3I7Z A;  4RHG A;  4GS0 A;  3O4S A;  1PTU A;  3D42 A;  2NLK A;  4YR8 B;  2P4D A;  3QCC A;  2A8B A;  1J4X A;  4OHH A;  1WAX A;  2C46 A;  4PYH A;  2CMA A;  2HY3 A;  1ONZ A;  3ZMP A;  5HDE A;  2CFV A;  2GWO A;  2F6Z A;  3RGQ A;  2RF6 A;  1C83 A;  4HRF A;  2IMG A;  4Z6B A;  3QCN A;  3O5X A;  4NX8 A;  2I1Y A;  3BLU A;  2VEY A;  2VEX A;  5KAB A;  1NNY A;  4AZ1 A;  3V0D A;  2CJZ A;  3F9B A;  2FH7 A;  4QUM A;  5BZZ A;  2NTA A;  3N0A A;  1ZC0 A;  1X24 A;  4OHL A;  4HJP A;  1VHR A;  2G6Z A;  3PS5 A;  4BPC A;  3QCD A;  2J16 B;  3QCG A;  3RO1 A;  1L8G A;  4HJQ A;  1OHE A;  4GE6 A;  4WOH A;  1MKP A;  1OET A;  4RDD A;  1NL9 A;  4KI9 A;  3EMU A;  3S3F A;  4GFU A;  2CM8 A;  3OLR A;  2BGE A;  1D5R A;  2I3U A;  3QCM A;  2CNI A;  3RZ2 A;  2B4S A;  4RH5 A;  3EB1 A;  2CNE A;  3QCK A;  4D3P A;  5BZX A;  4KYQ A;  5J8R A;  3S3K A;  2DXP A;  4I8N A;  2SHP A;  5M43 A;  3BM8 A;  4R0S A;  2QDP A;  4QAH A;  1YFO A;  1BZH A;  1ZCL A;  3O4T A;  1G7G A;  1YTN A;  2H4K A;  3EZZ A;  1YTS A;  1AAX A;  2OC3 A;  2B49 A;  5KA4 A;  1NZ7 A;  1OEU A;  1QXK A;  2H03 A;  4OHD A;  2J16 A;  1WCH A;  4YAA A;  1XXV A;  2B4O A;  2CNF A;  5KA8 A;  4QAP A;  2MBC A;  2VEV A;  2QCJ A;  4H1O A;  4R30 A;  1XM2 A;  3F41 A;  4ZI4 A;  1M3G A;  4GFV A;  1ONY A;  2GP0 A;  2QCT A;  1JF7 A;  4QBW A;  4B04 A;  4JMJ A;  2C7S A;  2E0T A;  3D1H A;  2BV5 A;  2H4G A;  4NWG A;  1T4J A;  4TVV A;  1OEM X;  3A5J A;  2G59 A;  1Q6M A;  1LQF A;  1Q1M A;  4QUN A;  2NZ6 A;  3AWE A;  2ZMM A;  5KAD A;  4ICZ A;  1XBO A;  1I9T A;  4DGX A;  4GE5 A;  1Q6T A;  3BRH A;  1EEO A;  1G7F A;  2AZR A;  4H34 A;  2GJT A;  1FQ1 A;  3QCL A;  5K9W A;  1EEN A;  3S3E A;  2I6I A;  1JLN A;  2QDM A;  5LXQ B;  3A5K A;  1C87 A;  2Y2F A;  3SR9 A;  3AWF A;  3D9C A;  1Q6S A;  2B07 A;  2I4E A;  1PA1 A;  1RXD A;  2I3R A;  2QBP A;  1LAR A;  2F46 A;  4GRZ A;  3ZMQ A;  2CMC A;  2I4H A;  5K25 A;  2BIJ A;  2PSZ A;  2Y96 A;  3ZM1 A;  2H04 A;  3QKP A;  1GWZ A;  4D3R A;  3RGO A;  4PVG A;  5KAA A;  3V0H A;  2AHS A;  3EU0 A;  4JNB A;  2B4P A;  1PA9 A;  2F6V A;  2VEW A;  1YGU A;  3D1Q A;  2NT7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...