2B4SA

Crystal structure of a complex between ptp1b and the insulin receptor tyrosine kinase
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
291
structure length
289
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Complex between Protein Tyrosine Phosphatase 1B and the Insulin Receptor Tyrosine Kinase.
pubmed doi rcsb
molecule tags Hydrolase/transferase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 95
structure length 289
sequence length 291
chains with identical sequence C
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2b4sA00
3QCFA 5K9WA 4NNDA 2VEUA 2CM2A 2GWOA 4Y14A 5LXQB 3LJ8A 4OHLA 4QAHA 2SHPA 3RGOA 4GRYA 3GXGA 1ECVA 4Y2EA 3PS5A 3F9BA 3OMHA 2NV5A 2IMGA 2P4DA 2F70A 1Q1MA 3S3KA 5BX1A 3O4UA 2OZ5A 2I6PA 1EENA 4QUNA 3NMEA 3U96A 1P15A 2G6ZA 2OUDA 3B7OA 4D3QA 3BM8A 2NT2A 4QAPA 1OEUA 3F81A 2I6OA 3O4SA 3ZMPA 5EHRA 1Q6NA 5K22A 1I9SA 5J8RA 4R0TA 5MMZB 2CM3A 3QCBA 2HC1A 1R6HA 2Y2FA 4NX8A 3QKPA 2B4OA 3S3FA 4RDDA 3EB1A 2C46A 5KA3A 2I6JA 3QCNA 1JF7A 2H03A 2B4PA 2B4SA 1G7FA 1G7GA 2B49A 1V3AA 1NZ7A 3I36A 5K24A 2H04A 2RF6A 2NLKA 5IBMA 1YGRA 2QBSA 1WRMA 1ZC0A 1NWEA 4HJPA 5KA2A 1C88A 1G4WR 2F6VA 1ZZWA 1OETA 2H4KA 4OHDA 2B4UA 2I75A 1X24A 3O3LA 4R30A 3AWEA 2HY3A 3S4EA 1PYNA 4YR8B 3RO1A 1C83A 3I80A 2JJDA 3A5JA 4HRFA 1QXKA 4RKKA 2OC3A 2BGEA 1YTWA 4RHGA 4ZRTA 4KYQA 1SUGA 5KA8A 3V0EA 4JMJA 4GFUA 5K25A 2BIJA 2I4EA 1XXVA 3MOWA 1NNYA 5KA7A 1L8GA 4TVVA 1OEMX 2I42A 1YN9A 2NTAA 4WU2A 4H34A 1YZ4A 3ZM2A 2A3KA 2AZRA 2HB1A 2H4VA 1NWLA 1XRIA 4DGXA 1XXPA 4OHIA 1G4US 2P6XA 3D1QA 1JLNA 1OHEA 1U25A 3M4UA 2FJNA 2BGDA 4JNBA 1G1HA 1KAVA 2QDCA 2VEWA 5EHPA 1ONZA 2F6WA 1I57A 4H1OA 4BPCA 2B07A 4GE2A 3SR9A 2GP0A 2Q47A 1I9TA 3A5KA 4PVGA 2I3UA 4AZ1A 1Q6PA 2E0TA 2FJMA 2ZN7A 1ZCLA 2I6IA 3H2XA 3V0JA 1NL9A 3EMUA 1ONYA 1Q6JA 4ZI4A 3ZMQA 3QCEA 3S3EA 3ZM3A 4NWFA 1VHRA 1LARA 3EZZA 1NO6A 2HVLA 3N0AA 1ZCKA 3QKQA 5KABA 1C84A 2ESBA 1BZHA 2HXPA 3AWGA 2CMBA 2FH7A 2R0BA 4PYHA 1YFOA 2CMCA 1OHCA 3D42A 4Z6BA 3GXHA 4RI5A 1Q6SA 2F6TA 1U24A 2PQ5A 3AWFA 4D3RA 3O4TA 5IBSA 2CNIA 2QBRA 4NYHA 4RI4A 4BJOA 1RXDA 1AAXA 5GTJA 4GFVA 3OLRA 4GE6A 2QDMA 4QBEA 4J51A 3V0HA 2PBNA 3V0GA 3S4OA 2I1YA 1BZJA 2BV5A 1YPTA 3ZV2A 4RH5A 1U26A 5AWXA 2WGPA 2F46A 2Y96A 3SMEA 1T48A 2HC2A 4ZN5A 2G59A 2QCTA 2F71A 2DXPA 2J17A 1XBOA 2VEXA 2CNEA 1PH0A 2MBCA 2Q05A 4GE5A 4GRZA 4R0SA 4S0GA 3RZ2A 1PTUA 1OHDA 1FQ1A 1T4JA 2H02A 2F6ZA 2C7SA 2J16A 3V0IA 5KACA 4DGPA 5BUGA 1Q6TA 1OESA 2B3OA 2I4HA 3QCDA 5KA9A 3V0FA 4JMKA 1C86A 1G1GA 3BRHA 1G1FA 1LQFA 3QCKA 1GFYA 5K23A 2VEYA 4KYRA 4YAAA 1LYVA 2PT0A 3EAXA 1A5YA 2CMAA 5I6VA 5K9VA 3V0DA 1RPMA 1QZ0A 1PA9A 4ICZA 1C87A 2CM7A 2I3RA 1WCHA 2CJZA 2PA5A 3EU0A 2CNHA 2PSZA 5BZXA 3ZM0A 5KAAA 4OHEA 3D1OA 3QCCA 4QBWA 3F9AA 5KA4A 2I6MA 2F6FA 2F6YA 4WU3A 4KI9A 4WOHA 2CNGA 3O5XA 1EEOA 1PTYA 1PA1A 2HNQA 4ERCA 2QBPA 3F99A 3QCGA 3ZM1A 3CM3A 1M3GA 4QUMA 1XM2A 1L8KA 2HCMA 4IKCA 4HJQA 1YTNA 4JBCA 4WTYA 1C85A 5BZZA 3QCIA 3CWEA 1T49A 4OHHA 2GJTA 3D9CA 5M43A 2H4GA 2M3VA 3QCLA 3QCHA 2NZ6A 3MMJA 2QDPA 1YGUA 2I5XA 1KAKA 2QBQA 2CNFA 2CM8A 2BZLA 4NWGA 2NT7A 1YTSA 4RH9A 3S3HA 5KADA 4D3PA 2QEPA 4I8NA 1MKPA 3RGQA 1YWFA 2I4GA 5KA0A 1OEOX 2J16B 2QCJA 1PTTA 1PTVA 2HNPA 3QCMA 3I7ZA 1FPZA 1OEVA 4GWFA 2ZMMA 1Q6MA 2A8BA 1J4XA 1BZCA 3D1HA 5KA1A 3F41A 4B04A 1GWZA 1PXHA 3MOZA 2YDUA 5HDEA 3BLTA 2AHSA 3D44A 2PI7A 4MBBA 1WAXA 2CFVA 2VEVA 1FPRA 4GS0A 2OOQA 1D5RA 3BLUA 3QCJA
chains in the Genus database with same CATH superfamily
3QCFA 5K9WA 4NNDA 2VEUA 2CM2A 2GWOA 4Y14A 5LXQB 3LJ8A 4OHLA 4QAHA 2SHPA 3RGOA 3ZM6A 4GRYA 3GXGA 1ECVA 4Y2EA 3PS5A 3F9BA 3OMHA 2NV5A 2IMGA 2P4DA 1EEHA 2F70A 1E0DA 1Q1MA 3S3KA 5BX1A 3O4UA 2OZ5A 2I6PA 1W7KA 1E8CA 1EENA 4QUNA 3NMEA 3U96A 1P15A 2G6ZA 2OUDA 3B7OA 4D3QA 3BM8A 2NT2A 4QAPA 1OEUA 3F81A 2I6OA 3O4SA 3ZMPA 5EHRA 2UUOA 1Q6NA 5K22A 1I9SA 5J8RA 4R0TA 5MMZB 2CM3A 3QCBA 2HC1A 1R6HA 2Y2FA 4NX8A 3QKPA 2B4OA 3S3FA 4RDDA 3EB1A 2C46A 5KA3A 2I6JA 3QCNA 1JF7A 2H03A 2Y67A 2B4PA 2B4SA 1G7FA 1G7GA 2B49A 1V3AA 1NZ7A 4CVKA 3I36A 5K24A 2H04A 2RF6A 1P3DA 2NLKA 5IBMA 1YGRA 2QBSA 1WRMA 1ZC0A 1NWEA 2GC6A 2GCAA 4HJPA 5KA2A 1C88A 1G4WR 1J6UA 2F6VA 1ZZWA 1OETA 2H4KA 4OHDA 2B4UA 2I75A 1X24A 3O3LA 4R30A 3AWEA 4CVMA 2HY3A 3S4EA 1PYNA 4YR8B 2UAGA 3RO1A 1C83A 3I80A 2JJDA 3ZL8A 3A5JA 4HRFA 1QXKA 4RKKA 2OC3A 2BGEA 1YTWA 2GCBA 4RHGA 4ZRTA 4KYQA 1SUGA 5KA8A 3V0EA 4JMJA 4GFUA 5K25A 2BIJA 2I4EA 1XXVA 3MOWA 1NNYA 5KA7A 1L8GA 4TVVA 1W78A 1OEMX 1GQYA 2I42A 1YN9A 2NTAA 4WU2A 4H34A 1YZ4A 3ZM2A 2A3KA 2AZRA 2HB1A 2H4VA 1NWLA 1XRIA 4DGXA 1XXPA 3LK7A 4OHIA 1G4US 2P6XA 2X5OA 3D1QA 1JLNA 1OHEA 1U25A 4QF5A 3M4UA 2FJNA 2XPCA 2BGDA 4JNBA 1G1HA 3PYZA 1KAVA 2QDCA 2VEWA 5EHPA 1ONZA 2F6WA 1I57A 4H1OA 4BPCA 2Y1OA 2B07A 4GE2A 3SR9A 2GP0A 2Q47A 1I9TA 4UAGA 3A5KA 4PVGA 2I3UA 4AZ1A 1Q6PA 2E0TA 2FJMA 2ZN7A 2VTDA 1O5ZA 1ZCLA 2I6IA 3H2XA 3V0JA 1NL9A 3EMUA 1ONYA 1Q6JA 4ZI4A 3ZMQA 3QCEA 2WTZA 3S3EA 3ZM3A 4NWFA 1VHRA 1LARA 3EZZA 1NO6A 2HVLA 3N0AA 3UAGA 2VORA 1ZCKA 3QKQA 5KABA 1C84A 2ESBA 1BZHA 2HXPA 3AWGA 3ZM5A 2CMBA 2FH7A 2R0BA 4PYHA 2Y66A 1YFOA 1P31A 2CMCA 1OHCA 3D42A 4Z6BA 3GXHA 4RI5A 1Q6SA 2F6TA 1U24A 2PQ5A 3AWFA 4D3RA 3O4TA 4CVLA 5IBSA 2CNIA 2QBRA 4NYHA 4RI4A 4BJOA 1RXDA 1GQQA 1AAXA 5GTJA 4ZIYA 4GFVA 3OLRA 4GE6A 3QCZA 2QDMA 4QBEA 4J51A 3V0HA 2PBNA 3V0GA 3S4OA 2I1YA 4HV4A 4QDIA 1BZJA 2BV5A 5A5FA 1YPTA 1UAGA 3ZV2A 4RH5A 1U26A 5AWXA 2WGPA 2F46A 2Y96A 2VTEA 3SMEA 3NRSA 1T48A 2HC2A 4ZN5A 2G59A 2QCTA 2JFHA 2F71A 2DXPA 2J17A 1XBOA 2VEXA 2CNEA 1PH0A 2MBCA 2Q05A 4GE5A 4GRZA 4R0SA 4S0GA 3RZ2A 1PTUA 1OHDA 1FQ1A 1T4JA 4C13A 2H02A 2F6ZA 2C7SA 2J16A 3V0IA 5KACA 4DGPA 5BUGA 1Q6TA 1OESA 2B3OA 2I4HA 3QCDA 5KA9A 1FGSA 3V0FA 4JMKA 1C86A 1G1GA 3BRHA 4BUBA 1G1FA 1LQFA 3QCKA 1GFYA 3MVNA 2AM1A 5K23A 2VEYA 4KYRA 2JFGA 4YAAA 1LYVA 2PT0A 3EAXA 1A5YA 2CMAA 5I6VA 5K9VA 3V0DA 1RPMA 1QZ0A 1PA9A 4ICZA 3HN7A 1C87A 2CM7A 2I3RA 1WCHA 2CJZA 2PA5A 3EU0A 2CNHA 2PSZA 5BZXA 3ZM0A 5KAAA 4OHEA 3D1OA 3QCCA 4QBWA 3F9AA 5KA4A 2I6MA 5A5EA 2F6FA 2AM2A 2F6YA 4WU3A 2WJPA 4KI9A 4WOHA 2CNGA 3O5XA 1EEOA 1PTYA 1PA1A 2HNQA 4ERCA 2QBPA 3F99A 3QCGA 3ZM1A 3CM3A 1M3GA 4QUMA 1XM2A 1L8KA 2HCMA 2UUPA 4IKCA 4HJQA 1YTNA 4JBCA 4WTYA 1C85A 5BZZA 3QCIA 3CWEA 1T49A 2JFFA 4C12A 4OHHA 2GJTA 3D9CA 5M43A 2H4GA 2M3VA 3QCLA 3QCHA 1JBWA 2NZ6A 3MMJA 2QDPA 1YGUA 2I5XA 2VOSA 1KAKA 2QBQA 2CNFA 2CM8A 2BZLA 4NWGA 2NT7A 1YTSA 4RH9A 3S3HA 2GC5A 5KADA 4D3PA 2QEPA 4I8NA 1MKPA 3N2AA 3RGQA 1YWFA 2I4GA 5KA0A 1OEOX 4BUCA 2J16B 2QCJA 1PTTA 1PTVA 2HNPA 3QCMA 3I7ZA 1FPZA 1OEVA 4GWFA 2ZMMA 1Q6MA 2A8BA 1J4XA 1BZCA 1GG4A 2F00A 3D1HA 3F41A 2Y68A 4B04A 5KA1A 1GWZA 1PXHA 3MOZA 2YDUA 5HDEA 3BLTA 2AHSA 3D44A 2PI7A 4MBBA 1JBVA 1WAXA 2CFVA 2XJAA 2VEVA 1FPRA 4GS0A 2OOQA 1D5RA 3BLUA 3QCJA
chains in the Genus database with same CATH topology
3QCFA 5K9WA 4NNDA 2VEUA 2CM2A 2GWOA 4Y14A 5LXQB 3LJ8A 4OHLA 4QAHA 2SHPA 3RGOA 4GRYA 3GXGA 1ECVA 4Y2EA 3PS5A 3F9BA 3OMHA 2NV5A 2IMGA 2P4DA 2F70A 1Q1MA 3S3KA 5BX1A 3O4UA 2OZ5A 2I6PA 1EENA 4QUNA 3NMEA 3U96A 1P15A 2G6ZA 2OUDA 3B7OA 4D3QA 3BM8A 2NT2A 4QAPA 1OEUA 3F81A 2I6OA 3O4SA 3ZMPA 5EHRA 1Q6NA 5K22A 1I9SA 5J8RA 4R0TA 5MMZB 2CM3A 3QCBA 2HC1A 1R6HA 2Y2FA 4NX8A 3QKPA 2B4OA 3S3FA 4RDDA 3EB1A 2C46A 5KA3A 2I6JA 3QCNA 1JF7A 2H03A 2B4PA 2B4SA 1G7FA 1G7GA 2B49A 1V3AA 1NZ7A 3I36A 5K24A 2H04A 2RF6A 2NLKA 5IBMA 1YGRA 2QBSA 1WRMA 1ZC0A 1NWEA 4HJPA 5KA2A 1C88A 1G4WR 2F6VA 1ZZWA 1OETA 2H4KA 4OHDA 2B4UA 2I75A 1X24A 3O3LA 4R30A 3AWEA 2HY3A 3S4EA 1PYNA 4YR8B 3RO1A 1C83A 3I80A 2JJDA 3A5JA 4HRFA 1QXKA 4RKKA 2OC3A 2BGEA 1YTWA 4RHGA 4ZRTA 4KYQA 1SUGA 5KA8A 3V0EA 4JMJA 4GFUA 5K25A 2BIJA 2I4EA 1XXVA 3MOWA 1NNYA 5KA7A 1L8GA 4TVVA 1OEMX 2I42A 1YN9A 2NTAA 4WU2A 4H34A 1YZ4A 3ZM2A 2A3KA 2AZRA 2HB1A 2H4VA 1NWLA 1XRIA 4DGXA 1XXPA 4OHIA 1G4US 2P6XA 3D1QA 1JLNA 1OHEA 1U25A 3M4UA 2FJNA 2BGDA 4JNBA 1G1HA 1KAVA 2QDCA 2VEWA 5EHPA 1ONZA 2F6WA 1I57A 4H1OA 4BPCA 2B07A 4GE2A 3SR9A 2GP0A 2Q47A 1I9TA 3A5KA 4PVGA 2I3UA 4AZ1A 1Q6PA 2E0TA 2FJMA 2ZN7A 1ZCLA 2I6IA 3H2XA 3V0JA 1NL9A 3EMUA 1ONYA 1Q6JA 4ZI4A 3ZMQA 3QCEA 3S3EA 3ZM3A 4NWFA 1VHRA 1LARA 3EZZA 1NO6A 2HVLA 3N0AA 1ZCKA 3QKQA 5KABA 1C84A 2ESBA 1BZHA 2HXPA 3AWGA 2CMBA 2FH7A 2R0BA 4PYHA 1YFOA 2CMCA 1OHCA 3D42A 4Z6BA 3GXHA 4RI5A 1Q6SA 2F6TA 1U24A 2PQ5A 3AWFA 4D3RA 3O4TA 5IBSA 2CNIA 2QBRA 4NYHA 4RI4A 4BJOA 1RXDA 1AAXA 5GTJA 4GFVA 3OLRA 4GE6A 2QDMA 4QBEA 4J51A 3V0HA 2PBNA 3V0GA 3S4OA 2I1YA 1BZJA 2BV5A 1YPTA 3ZV2A 4RH5A 1U26A 5AWXA 2WGPA 2F46A 2Y96A 3SMEA 1T48A 2HC2A 4ZN5A 2G59A 2QCTA 2F71A 2DXPA 2J17A 1XBOA 2VEXA 2CNEA 1PH0A 2MBCA 2Q05A 4GE5A 4GRZA 4R0SA 4S0GA 3RZ2A 1PTUA 1OHDA 1FQ1A 1T4JA 2H02A 2F6ZA 2C7SA 2J16A 3V0IA 5KACA 4DGPA 5BUGA 1Q6TA 1OESA 2B3OA 2I4HA 3QCDA 5KA9A 3V0FA 4JMKA 1C86A 1G1GA 3BRHA 1G1FA 1LQFA 3QCKA 1GFYA 5K23A 2VEYA 4KYRA 4YAAA 1LYVA 2PT0A 3EAXA 1A5YA 2CMAA 5I6VA 5K9VA 3V0DA 1RPMA 1QZ0A 1PA9A 4ICZA 1C87A 2CM7A 2I3RA 1WCHA 2CJZA 2PA5A 3EU0A 2CNHA 2PSZA 5BZXA 3ZM0A 5KAAA 4OHEA 3D1OA 3QCCA 4QBWA 3F9AA 5KA4A 2I6MA 2F6FA 2F6YA 4WU3A 4KI9A 4WOHA 2CNGA 3O5XA 1EEOA 1PTYA 1PA1A 2HNQA 4ERCA 2QBPA 3F99A 3QCGA 3ZM1A 3CM3A 1M3GA 4QUMA 1XM2A 1L8KA 2HCMA 4IKCA 4HJQA 1YTNA 4JBCA 4WTYA 1C85A 5BZZA 3QCIA 3CWEA 1T49A 4OHHA 2GJTA 3D9CA 5M43A 2H4GA 2M3VA 3QCLA 3QCHA 2NZ6A 3MMJA 2QDPA 1YGUA 2I5XA 1KAKA 2QBQA 2CNFA 2CM8A 2BZLA 4NWGA 2NT7A 1YTSA 4RH9A 3S3HA 5KADA 4D3PA 2QEPA 4I8NA 1MKPA 3RGQA 1YWFA 2I4GA 5KA0A 1OEOX 2J16B 2QCJA 1PTTA 1PTVA 2HNPA 3QCMA 3I7ZA 1FPZA 1OEVA 4GWFA 2ZMMA 1Q6MA 2A8BA 1J4XA 1BZCA 3D1HA 5KA1A 3F41A 4B04A 1GWZA 1PXHA 3MOZA 2YDUA 5HDEA 3BLTA 2AHSA 3D44A 2PI7A 4MBBA 1WAXA 2CFVA 2VEVA 1FPRA 4GS0A 2OOQA 1D5RA 3BLUA 3QCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCF A;  5K9W A;  4NND A;  2VEU A;  2CM2 A;  2GWO A;  4Y14 A;  5LXQ B;  3LJ8 A;  4OHL A;  4QAH A;  2SHP A;  3RGO A;  4GRY A;  3GXG A;  1ECV A;  4Y2E A;  3PS5 A;  3F9B A;  3OMH A;  2NV5 A;  2IMG A;  2P4D A;  2F70 A;  1Q1M A;  3S3K A;  5BX1 A;  3O4U A;  2OZ5 A;  2I6P A;  1EEN A;  4QUN A;  3NME A;  3U96 A;  1P15 A;  2G6Z A;  2OUD A;  3B7O A;  4D3Q A;  3BM8 A;  2NT2 A;  4QAP A;  1OEU A;  3F81 A;  2I6O A;  3O4S A;  3ZMP A;  5EHR A;  1Q6N A;  5K22 A;  1I9S A;  5J8R A;  4R0T A;  5MMZ B;  2CM3 A;  3QCB A;  2HC1 A;  1R6H A;  2Y2F A;  4NX8 A;  3QKP A;  2B4O A;  3S3F A;  4RDD A;  3EB1 A;  2C46 A;  5KA3 A;  2I6J A;  3QCN A;  1JF7 A;  2H03 A;  2B4P A;  2B4S A;  1G7F A;  1G7G A;  2B49 A;  1V3A A;  1NZ7 A;  3I36 A;  5K24 A;  2H04 A;  2RF6 A;  2NLK A;  5IBM A;  1YGR A;  2QBS A;  1WRM A;  1ZC0 A;  1NWE A;  4HJP A;  5KA2 A;  1C88 A;  1G4W R;  2F6V A;  1ZZW A;  1OET A;  2H4K A;  4OHD A;  2B4U A;  2I75 A;  1X24 A;  3O3L A;  4R30 A;  3AWE A;  2HY3 A;  3S4E A;  1PYN A;  4YR8 B;  3RO1 A;  1C83 A;  3I80 A;  2JJD A;  3A5J A;  4HRF A;  1QXK A;  4RKK A;  2OC3 A;  2BGE A;  1YTW A;  4RHG A;  4ZRT A;  4KYQ A;  1SUG A;  5KA8 A;  3V0E A;  4JMJ A;  4GFU A;  5K25 A;  2BIJ A;  2I4E A;  1XXV A;  3MOW A;  1NNY A;  5KA7 A;  1L8G A;  4TVV A;  1OEM X;  2I42 A;  1YN9 A;  2NTA A;  4WU2 A;  4H34 A;  1YZ4 A;  3ZM2 A;  2A3K A;  2AZR A;  2HB1 A;  2H4V A;  1NWL A;  1XRI A;  4DGX A;  1XXP A;  4OHI A;  1G4U S;  2P6X A;  3D1Q A;  1JLN A;  1OHE A;  1U25 A;  3M4U A;  2FJN A;  2BGD A;  4JNB A;  1G1H A;  1KAV A;  2QDC A;  2VEW A;  5EHP A;  1ONZ A;  2F6W A;  1I57 A;  4H1O A;  4BPC A;  2B07 A;  4GE2 A;  3SR9 A;  2GP0 A;  2Q47 A;  1I9T A;  3A5K A;  4PVG A;  2I3U A;  4AZ1 A;  1Q6P A;  2E0T A;  2FJM A;  2ZN7 A;  1ZCL A;  2I6I A;  3H2X A;  3V0J A;  1NL9 A;  3EMU A;  1ONY A;  1Q6J A;  4ZI4 A;  3ZMQ A;  3QCE A;  3S3E A;  3ZM3 A;  4NWF A;  1VHR A;  1LAR A;  3EZZ A;  1NO6 A;  2HVL A;  3N0A A;  1ZCK A;  3QKQ A;  5KAB A;  1C84 A;  2ESB A;  1BZH A;  2HXP A;  3AWG A;  2CMB A;  2FH7 A;  2R0B A;  4PYH A;  1YFO A;  2CMC A;  1OHC A;  3D42 A;  4Z6B A;  3GXH A;  4RI5 A;  1Q6S A;  2F6T A;  1U24 A;  2PQ5 A;  3AWF A;  4D3R A;  3O4T A;  5IBS A;  2CNI A;  2QBR A;  4NYH A;  4RI4 A;  4BJO A;  1RXD A;  1AAX A;  5GTJ A;  4GFV A;  3OLR A;  4GE6 A;  2QDM A;  4QBE A;  4J51 A;  3V0H A;  2PBN A;  3V0G A;  3S4O A;  2I1Y A;  1BZJ A;  2BV5 A;  1YPT A;  3ZV2 A;  4RH5 A;  1U26 A;  5AWX A;  2WGP A;  2F46 A;  2Y96 A;  3SME A;  1T48 A;  2HC2 A;  4ZN5 A;  2G59 A;  2QCT A;  2F71 A;  2DXP A;  2J17 A;  1XBO A;  2VEX A;  2CNE A;  1PH0 A;  2MBC A;  2Q05 A;  4GE5 A;  4GRZ A;  4R0S A;  4S0G A;  3RZ2 A;  1PTU A;  1OHD A;  1FQ1 A;  1T4J A;  2H02 A;  2F6Z A;  2C7S A;  2J16 A;  3V0I A;  5KAC A;  4DGP A;  5BUG A;  1Q6T A;  1OES A;  2B3O A;  2I4H A;  3QCD A;  5KA9 A;  3V0F A;  4JMK A;  1C86 A;  1G1G A;  3BRH A;  1G1F A;  1LQF A;  3QCK A;  1GFY A;  5K23 A;  2VEY A;  4KYR A;  4YAA A;  1LYV A;  2PT0 A;  3EAX A;  1A5Y A;  2CMA A;  5I6V A;  5K9V A;  3V0D A;  1RPM A;  1QZ0 A;  1PA9 A;  4ICZ A;  1C87 A;  2CM7 A;  2I3R A;  1WCH A;  2CJZ A;  2PA5 A;  3EU0 A;  2CNH A;  2PSZ A;  5BZX A;  3ZM0 A;  5KAA A;  4OHE A;  3D1O A;  3QCC A;  4QBW A;  3F9A A;  5KA4 A;  2I6M A;  2F6F A;  2F6Y A;  4WU3 A;  4KI9 A;  4WOH A;  2CNG A;  3O5X A;  1EEO A;  1PTY A;  1PA1 A;  2HNQ A;  4ERC A;  2QBP A;  3F99 A;  3QCG A;  3ZM1 A;  3CM3 A;  1M3G A;  4QUM A;  1XM2 A;  1L8K A;  2HCM A;  4IKC A;  4HJQ A;  1YTN A;  4JBC A;  4WTY A;  1C85 A;  5BZZ A;  3QCI A;  3CWE A;  1T49 A;  4OHH A;  2GJT A;  3D9C A;  5M43 A;  2H4G A;  2M3V A;  3QCL A;  3QCH A;  2NZ6 A;  3MMJ A;  2QDP A;  1YGU A;  2I5X A;  1KAK A;  2QBQ A;  2CNF A;  2CM8 A;  2BZL A;  4NWG A;  2NT7 A;  1YTS A;  4RH9 A;  3S3H A;  5KAD A;  4D3P A;  2QEP A;  4I8N A;  1MKP A;  3RGQ A;  1YWF A;  2I4G A;  5KA0 A;  1OEO X;  2J16 B;  2QCJ A;  1PTT A;  1PTV A;  2HNP A;  3QCM A;  3I7Z A;  1FPZ A;  1OEV A;  4GWF A;  2ZMM A;  1Q6M A;  2A8B A;  1J4X A;  1BZC A;  3D1H A;  5KA1 A;  3F41 A;  4B04 A;  1GWZ A;  1PXH A;  3MOZ A;  2YDU A;  5HDE A;  3BLT A;  2AHS A;  3D44 A;  2PI7 A;  4MBB A;  1WAX A;  2CFV A;  2VEV A;  1FPR A;  4GS0 A;  2OOQ A;  1D5R A;  3BLU A;  3QCJ A; 
#chains in the Genus database with same CATH topology
 3QCF A;  5K9W A;  4NND A;  2VEU A;  2CM2 A;  2GWO A;  4Y14 A;  5LXQ B;  3LJ8 A;  4OHL A;  4QAH A;  2SHP A;  3RGO A;  3ZM6 A;  4GRY A;  3GXG A;  1ECV A;  4Y2E A;  3PS5 A;  3F9B A;  3OMH A;  2NV5 A;  2IMG A;  2P4D A;  1EEH A;  2F70 A;  1E0D A;  1Q1M A;  3S3K A;  5BX1 A;  3O4U A;  2OZ5 A;  2I6P A;  1W7K A;  1E8C A;  1EEN A;  4QUN A;  3NME A;  3U96 A;  1P15 A;  2G6Z A;  2OUD A;  3B7O A;  4D3Q A;  3BM8 A;  2NT2 A;  4QAP A;  1OEU A;  3F81 A;  2I6O A;  3O4S A;  3ZMP A;  5EHR A;  2UUO A;  1Q6N A;  5K22 A;  1I9S A;  5J8R A;  4R0T A;  5MMZ B;  2CM3 A;  3QCB A;  2HC1 A;  1R6H A;  2Y2F A;  4NX8 A;  3QKP A;  2B4O A;  3S3F A;  4RDD A;  3EB1 A;  2C46 A;  5KA3 A;  2I6J A;  3QCN A;  1JF7 A;  2H03 A;  2Y67 A;  2B4P A;  2B4S A;  1G7F A;  1G7G A;  2B49 A;  1V3A A;  1NZ7 A;  4CVK A;  3I36 A;  5K24 A;  2H04 A;  2RF6 A;  1P3D A;  2NLK A;  5IBM A;  1YGR A;  2QBS A;  1WRM A;  1ZC0 A;  1NWE A;  2GC6 A;  2GCA A;  4HJP A;  5KA2 A;  1C88 A;  1G4W R;  1J6U A;  2F6V A;  1ZZW A;  1OET A;  2H4K A;  4OHD A;  2B4U A;  2I75 A;  1X24 A;  3O3L A;  4R30 A;  3AWE A;  4CVM A;  2HY3 A;  3S4E A;  1PYN A;  4YR8 B;  2UAG A;  3RO1 A;  1C83 A;  3I80 A;  2JJD A;  3ZL8 A;  3A5J A;  4HRF A;  1QXK A;  4RKK A;  2OC3 A;  2BGE A;  1YTW A;  2GCB A;  4RHG A;  4ZRT A;  4KYQ A;  1SUG A;  5KA8 A;  3V0E A;  4JMJ A;  4GFU A;  5K25 A;  2BIJ A;  2I4E A;  1XXV A;  3MOW A;  1NNY A;  5KA7 A;  1L8G A;  4TVV A;  1W78 A;  1OEM X;  1GQY A;  2I42 A;  1YN9 A;  2NTA A;  4WU2 A;  4H34 A;  1YZ4 A;  3ZM2 A;  2A3K A;  2AZR A;  2HB1 A;  2H4V A;  1NWL A;  1XRI A;  4DGX A;  1XXP A;  3LK7 A;  4OHI A;  1G4U S;  2P6X A;  2X5O A;  3D1Q A;  1JLN A;  1OHE A;  1U25 A;  4QF5 A;  3M4U A;  2FJN A;  2XPC A;  2BGD A;  4JNB A;  1G1H A;  3PYZ A;  1KAV A;  2QDC A;  2VEW A;  5EHP A;  1ONZ A;  2F6W A;  1I57 A;  4H1O A;  4BPC A;  2Y1O A;  2B07 A;  4GE2 A;  3SR9 A;  2GP0 A;  2Q47 A;  1I9T A;  4UAG A;  3A5K A;  4PVG A;  2I3U A;  4AZ1 A;  1Q6P A;  2E0T A;  2FJM A;  2ZN7 A;  2VTD A;  1O5Z A;  1ZCL A;  2I6I A;  3H2X A;  3V0J A;  1NL9 A;  3EMU A;  1ONY A;  1Q6J A;  4ZI4 A;  3ZMQ A;  3QCE A;  2WTZ A;  3S3E A;  3ZM3 A;  4NWF A;  1VHR A;  1LAR A;  3EZZ A;  1NO6 A;  2HVL A;  3N0A A;  3UAG A;  2VOR A;  1ZCK A;  3QKQ A;  5KAB A;  1C84 A;  2ESB A;  1BZH A;  2HXP A;  3AWG A;  3ZM5 A;  2CMB A;  2FH7 A;  2R0B A;  4PYH A;  2Y66 A;  1YFO A;  1P31 A;  2CMC A;  1OHC A;  3D42 A;  4Z6B A;  3GXH A;  4RI5 A;  1Q6S A;  2F6T A;  1U24 A;  2PQ5 A;  3AWF A;  4D3R A;  3O4T A;  4CVL A;  5IBS A;  2CNI A;  2QBR A;  4NYH A;  4RI4 A;  4BJO A;  1RXD A;  1GQQ A;  1AAX A;  5GTJ A;  4ZIY A;  4GFV A;  3OLR A;  4GE6 A;  3QCZ A;  2QDM A;  4QBE A;  4J51 A;  3V0H A;  2PBN A;  3V0G A;  3S4O A;  2I1Y A;  4HV4 A;  4QDI A;  1BZJ A;  2BV5 A;  5A5F A;  1YPT A;  1UAG A;  3ZV2 A;  4RH5 A;  1U26 A;  5AWX A;  2WGP A;  2F46 A;  2Y96 A;  2VTE A;  3SME A;  3NRS A;  1T48 A;  2HC2 A;  4ZN5 A;  2G59 A;  2QCT A;  2JFH A;  2F71 A;  2DXP A;  2J17 A;  1XBO A;  2VEX A;  2CNE A;  1PH0 A;  2MBC A;  2Q05 A;  4GE5 A;  4GRZ A;  4R0S A;  4S0G A;  3RZ2 A;  1PTU A;  1OHD A;  1FQ1 A;  1T4J A;  4C13 A;  2H02 A;  2F6Z A;  2C7S A;  2J16 A;  3V0I A;  5KAC A;  4DGP A;  5BUG A;  1Q6T A;  1OES A;  2B3O A;  2I4H A;  3QCD A;  5KA9 A;  1FGS A;  3V0F A;  4JMK A;  1C86 A;  1G1G A;  3BRH A;  4BUB A;  1G1F A;  1LQF A;  3QCK A;  1GFY A;  3MVN A;  2AM1 A;  5K23 A;  2VEY A;  4KYR A;  2JFG A;  4YAA A;  1LYV A;  2PT0 A;  3EAX A;  1A5Y A;  2CMA A;  5I6V A;  5K9V A;  3V0D A;  1RPM A;  1QZ0 A;  1PA9 A;  4ICZ A;  3HN7 A;  1C87 A;  2CM7 A;  2I3R A;  1WCH A;  2CJZ A;  2PA5 A;  3EU0 A;  2CNH A;  2PSZ A;  5BZX A;  3ZM0 A;  5KAA A;  4OHE A;  3D1O A;  3QCC A;  4QBW A;  3F9A A;  5KA4 A;  2I6M A;  5A5E A;  2F6F A;  2AM2 A;  2F6Y A;  4WU3 A;  2WJP A;  4KI9 A;  4WOH A;  2CNG A;  3O5X A;  1EEO A;  1PTY A;  1PA1 A;  2HNQ A;  4ERC A;  2QBP A;  3F99 A;  3QCG A;  3ZM1 A;  3CM3 A;  1M3G A;  4QUM A;  1XM2 A;  1L8K A;  2HCM A;  2UUP A;  4IKC A;  4HJQ A;  1YTN A;  4JBC A;  4WTY A;  1C85 A;  5BZZ A;  3QCI A;  3CWE A;  1T49 A;  2JFF A;  4C12 A;  4OHH A;  2GJT A;  3D9C A;  5M43 A;  2H4G A;  2M3V A;  3QCL A;  3QCH A;  1JBW A;  2NZ6 A;  3MMJ A;  2QDP A;  1YGU A;  2I5X A;  2VOS A;  1KAK A;  2QBQ A;  2CNF A;  2CM8 A;  2BZL A;  4NWG A;  2NT7 A;  1YTS A;  4RH9 A;  3S3H A;  2GC5 A;  5KAD A;  4D3P A;  2QEP A;  4I8N A;  1MKP A;  3N2A A;  3RGQ A;  1YWF A;  2I4G A;  5KA0 A;  1OEO X;  4BUC A;  2J16 B;  2QCJ A;  1PTT A;  1PTV A;  2HNP A;  3QCM A;  3I7Z A;  1FPZ A;  1OEV A;  4GWF A;  2ZMM A;  1Q6M A;  2A8B A;  1J4X A;  1BZC A;  1GG4 A;  2F00 A;  3D1H A;  3F41 A;  2Y68 A;  4B04 A;  5KA1 A;  1GWZ A;  1PXH A;  3MOZ A;  2YDU A;  5HDE A;  3BLT A;  2AHS A;  3D44 A;  2PI7 A;  4MBB A;  1JBV A;  1WAX A;  2CFV A;  2XJA A;  2VEV A;  1FPR A;  4GS0 A;  2OOQ A;  1D5R A;  3BLU A;  3QCJ A; 
#chains in the Genus database with same CATH homology
 3QCF A;  5K9W A;  4NND A;  2VEU A;  2CM2 A;  2GWO A;  4Y14 A;  5LXQ B;  3LJ8 A;  4OHL A;  4QAH A;  2SHP A;  3RGO A;  4GRY A;  3GXG A;  1ECV A;  4Y2E A;  3PS5 A;  3F9B A;  3OMH A;  2NV5 A;  2IMG A;  2P4D A;  2F70 A;  1Q1M A;  3S3K A;  5BX1 A;  3O4U A;  2OZ5 A;  2I6P A;  1EEN A;  4QUN A;  3NME A;  3U96 A;  1P15 A;  2G6Z A;  2OUD A;  3B7O A;  4D3Q A;  3BM8 A;  2NT2 A;  4QAP A;  1OEU A;  3F81 A;  2I6O A;  3O4S A;  3ZMP A;  5EHR A;  1Q6N A;  5K22 A;  1I9S A;  5J8R A;  4R0T A;  5MMZ B;  2CM3 A;  3QCB A;  2HC1 A;  1R6H A;  2Y2F A;  4NX8 A;  3QKP A;  2B4O A;  3S3F A;  4RDD A;  3EB1 A;  2C46 A;  5KA3 A;  2I6J A;  3QCN A;  1JF7 A;  2H03 A;  2B4P A;  2B4S A;  1G7F A;  1G7G A;  2B49 A;  1V3A A;  1NZ7 A;  3I36 A;  5K24 A;  2H04 A;  2RF6 A;  2NLK A;  5IBM A;  1YGR A;  2QBS A;  1WRM A;  1ZC0 A;  1NWE A;  4HJP A;  5KA2 A;  1C88 A;  1G4W R;  2F6V A;  1ZZW A;  1OET A;  2H4K A;  4OHD A;  2B4U A;  2I75 A;  1X24 A;  3O3L A;  4R30 A;  3AWE A;  2HY3 A;  3S4E A;  1PYN A;  4YR8 B;  3RO1 A;  1C83 A;  3I80 A;  2JJD A;  3A5J A;  4HRF A;  1QXK A;  4RKK A;  2OC3 A;  2BGE A;  1YTW A;  4RHG A;  4ZRT A;  4KYQ A;  1SUG A;  5KA8 A;  3V0E A;  4JMJ A;  4GFU A;  5K25 A;  2BIJ A;  2I4E A;  1XXV A;  3MOW A;  1NNY A;  5KA7 A;  1L8G A;  4TVV A;  1OEM X;  2I42 A;  1YN9 A;  2NTA A;  4WU2 A;  4H34 A;  1YZ4 A;  3ZM2 A;  2A3K A;  2AZR A;  2HB1 A;  2H4V A;  1NWL A;  1XRI A;  4DGX A;  1XXP A;  4OHI A;  1G4U S;  2P6X A;  3D1Q A;  1JLN A;  1OHE A;  1U25 A;  3M4U A;  2FJN A;  2BGD A;  4JNB A;  1G1H A;  1KAV A;  2QDC A;  2VEW A;  5EHP A;  1ONZ A;  2F6W A;  1I57 A;  4H1O A;  4BPC A;  2B07 A;  4GE2 A;  3SR9 A;  2GP0 A;  2Q47 A;  1I9T A;  3A5K A;  4PVG A;  2I3U A;  4AZ1 A;  1Q6P A;  2E0T A;  2FJM A;  2ZN7 A;  1ZCL A;  2I6I A;  3H2X A;  3V0J A;  1NL9 A;  3EMU A;  1ONY A;  1Q6J A;  4ZI4 A;  3ZMQ A;  3QCE A;  3S3E A;  3ZM3 A;  4NWF A;  1VHR A;  1LAR A;  3EZZ A;  1NO6 A;  2HVL A;  3N0A A;  1ZCK A;  3QKQ A;  5KAB A;  1C84 A;  2ESB A;  1BZH A;  2HXP A;  3AWG A;  2CMB A;  2FH7 A;  2R0B A;  4PYH A;  1YFO A;  2CMC A;  1OHC A;  3D42 A;  4Z6B A;  3GXH A;  4RI5 A;  1Q6S A;  2F6T A;  1U24 A;  2PQ5 A;  3AWF A;  4D3R A;  3O4T A;  5IBS A;  2CNI A;  2QBR A;  4NYH A;  4RI4 A;  4BJO A;  1RXD A;  1AAX A;  5GTJ A;  4GFV A;  3OLR A;  4GE6 A;  2QDM A;  4QBE A;  4J51 A;  3V0H A;  2PBN A;  3V0G A;  3S4O A;  2I1Y A;  1BZJ A;  2BV5 A;  1YPT A;  3ZV2 A;  4RH5 A;  1U26 A;  5AWX A;  2WGP A;  2F46 A;  2Y96 A;  3SME A;  1T48 A;  2HC2 A;  4ZN5 A;  2G59 A;  2QCT A;  2F71 A;  2DXP A;  2J17 A;  1XBO A;  2VEX A;  2CNE A;  1PH0 A;  2MBC A;  2Q05 A;  4GE5 A;  4GRZ A;  4R0S A;  4S0G A;  3RZ2 A;  1PTU A;  1OHD A;  1FQ1 A;  1T4J A;  2H02 A;  2F6Z A;  2C7S A;  2J16 A;  3V0I A;  5KAC A;  4DGP A;  5BUG A;  1Q6T A;  1OES A;  2B3O A;  2I4H A;  3QCD A;  5KA9 A;  3V0F A;  4JMK A;  1C86 A;  1G1G A;  3BRH A;  1G1F A;  1LQF A;  3QCK A;  1GFY A;  5K23 A;  2VEY A;  4KYR A;  4YAA A;  1LYV A;  2PT0 A;  3EAX A;  1A5Y A;  2CMA A;  5I6V A;  5K9V A;  3V0D A;  1RPM A;  1QZ0 A;  1PA9 A;  4ICZ A;  1C87 A;  2CM7 A;  2I3R A;  1WCH A;  2CJZ A;  2PA5 A;  3EU0 A;  2CNH A;  2PSZ A;  5BZX A;  3ZM0 A;  5KAA A;  4OHE A;  3D1O A;  3QCC A;  4QBW A;  3F9A A;  5KA4 A;  2I6M A;  2F6F A;  2F6Y A;  4WU3 A;  4KI9 A;  4WOH A;  2CNG A;  3O5X A;  1EEO A;  1PTY A;  1PA1 A;  2HNQ A;  4ERC A;  2QBP A;  3F99 A;  3QCG A;  3ZM1 A;  3CM3 A;  1M3G A;  4QUM A;  1XM2 A;  1L8K A;  2HCM A;  4IKC A;  4HJQ A;  1YTN A;  4JBC A;  4WTY A;  1C85 A;  5BZZ A;  3QCI A;  3CWE A;  1T49 A;  4OHH A;  2GJT A;  3D9C A;  5M43 A;  2H4G A;  2M3V A;  3QCL A;  3QCH A;  2NZ6 A;  3MMJ A;  2QDP A;  1YGU A;  2I5X A;  1KAK A;  2QBQ A;  2CNF A;  2CM8 A;  2BZL A;  4NWG A;  2NT7 A;  1YTS A;  4RH9 A;  3S3H A;  5KAD A;  4D3P A;  2QEP A;  4I8N A;  1MKP A;  3RGQ A;  1YWF A;  2I4G A;  5KA0 A;  1OEO X;  2J16 B;  2QCJ A;  1PTT A;  1PTV A;  2HNP A;  3QCM A;  3I7Z A;  1FPZ A;  1OEV A;  4GWF A;  2ZMM A;  1Q6M A;  2A8B A;  1J4X A;  1BZC A;  3D1H A;  5KA1 A;  3F41 A;  4B04 A;  1GWZ A;  1PXH A;  3MOZ A;  2YDU A;  5HDE A;  3BLT A;  2AHS A;  3D44 A;  2PI7 A;  4MBB A;  1WAX A;  2CFV A;  2VEV A;  1FPR A;  4GS0 A;  2OOQ A;  1D5R A;  3BLU A;  3QCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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