2BGEA

Structure-based design of protein tyrosine phosphatase-1b inhibitors
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
297
structure length
297
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 108
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2bgeA00
3QCCA 3EAXA 1I9SA 4QAHA 1ECVA 4RKKA 3F41A 3AWEA 2I4GA 2B4OA 2H4GA 3SMEA 3D42A 4JMJA 2WGPA 1VHRA 2QDPA 1T48A 5KA4A 4RI4A 1C86A 4R30A 5LXQB 4OHDA 4RHGA 1ONZA 1YWFA 1PTTA 1PTVA 3QCLA 2HNPA 4ICZA 2HXPA 3BM8A 5BZXA 4JNBA 2RF6A 2I75A 2VEUA 2B4UA 1LYVA 2F6FA 4D3QA 2F6ZA 1OHDA 1LQFA 4HJQA 1V3AA 3I36A 4PYHA 2P6XA 1JF7A 4R0SA 1J4XA 1G4WR 3B7OA 2I4EA 2CMAA 4OHLA 1L8KA 2NZ6A 2GP0A 1G7FA 3EZZA 3QCIA 1A5YA 1YPTA 4IKCA 1YN9A 1G4US 3QCBA 3V0HA 4NX8A 1EENA 2H03A 2QBPA 2G6ZA 2I6JA 1I57A 2CNEA 1OEVA 1WRMA 5BUGA 2Q05A 1ONYA 1QZ0A 2PI7A 1C87A 1G1GA 2QEPA 2B4PA 3D1HA 2CMBA 3U96A 1PYNA 1ZCLA 4WOHA 2H4VA 4MBBA 4S0GA 2F6TA 2I6OA 2J16B 1P15A 5EHRA 1QXKA 4D3PA 3S3FA 1OEMX 4GWFA 1Q6JA 5EHPA 3CM3A 2E0TA 2I6PA 3QCFA 2M3VA 2H04A 1LARA 1OHCA 1KAVA 3F99A 2JJDA 3V0JA 3OMHA 4NNDA 3V0EA 5KA0A 2HC2A 4ZI4A 2Y2FA 3QCJA 5IBSA 1RPMA 1GFYA 4Y2EA 3EB1A 4RH9A 5I6VA 3F9AA 4QAPA 1ZCKA 5GTJA 3S3EA 1U25A 2HVLA 3V0FA 1C83A 2I6MA 2NV5A 3V0GA 1PTUA 4OHHA 4KI9A 4GS0A 2OC3A 3EU0A 3MMJA 4WU2A 2ESBA 1OEOX 2QBRA 4GE5A 1Q6NA 5K9WA 4QBEA 3OLRA 1SUGA 1OESA 1OEUA 3RGQA 1C85A 1FPZA 5KA8A 3S4OA 3EMUA 2F70A 2QCTA 2CMCA 4R0TA 3ZM2A 3LJ8A 4WU3A 5K25A 2F6VA 4D3RA 1PTYA 3ZM0A 1WCHA 1FQ1A 5AWXA 1Q6SA 2PQ5A 5KA7A 3AWFA 2CM2A 3S4EA 3V0IA 4DGXA 4JBCA 4RI5A 4JMKA 2FJMA 2ZN7A 1U24A 3QCKA 2HC1A 2I6IA 2PSZA 1OHEA 4NYHA 3N0AA 3S3KA 4I8NA 1C88A 2J17A 4RH5A 5IBMA 3CWEA 5BZZA 3QCMA 2PA5A 5KADA 2BGDA 3M4UA 4YAAA 5KAAA 1G7GA 2J16A 1BZJA 3D9CA 5KABA 2OUDA 2A3KA 2QDMA 4J51A 4OHIA 2VEYA 2NT7A 2QBQA 1ZC0A 5K23A 5MMZB 2BGEA 3RGOA 3O3LA 3A5JA 3GXGA 2G59A 4GRZA 1NO6A 2PBNA 4HJPA 3O4TA 5HDEA 2CNIA 4GRYA 2QBSA 1YGRA 5J8RA 3ZMPA 2R0BA 2C46A 1RXDA 2ZMMA 2C7SA 4NWFA 2F6YA 4BJOA 1Q6MA 2IMGA 2B07A 5K9VA 4ERCA 5BX1A 2Q47A 4KYRA 3MOZA 3ZMQA 3O4SA 2CJZA 2HNQA 3RO1A 4HRFA 1KAKA 2FJNA 2NT2A 3QCNA 5KA1A 3V0DA 2B3OA 3QCDA 4DGPA 3BLTA 2PT0A 2CNFA 3MOWA 5KA9A 4B04A 4GFUA 1I9TA 2CM8A 3RZ2A 3ZM1A 5KA2A 2NTAA 1YTWA 2AZRA 4H34A 1MKPA 1YTNA 1EEOA 4RDDA 1Q6PA 2F46A 2HY3A 2YDUA 1T4JA 2F71A 1T49A 2DXPA 2CM3A 4YR8B 3O4UA 4GE6A 2BIJA 1NWLA 2I42A 2VEVA 1XBOA 3PS5A 1Q6TA 3D1QA 3D1OA 2I4HA 4AZ1A 3D44A 1Q1MA 1WAXA 1PH0A 1XXVA 1M3GA 2I3RA 2AHSA 2HB1A 1YZ4A 4TVVA 1X24A 3GXHA 1BZCA 2CFVA 2NLKA 4OHEA 1YTSA 2A8BA 2OOQA 1NZ7A 1D5RA 4QUMA 4ZN5A 4QUNA 5M43A 4QBWA 4PVGA 1FPRA 2H02A 3A5KA 1BZHA 1YFOA 3QKPA 4GFVA 1NNYA 2CNHA 1JLNA 1NL9A 4ZRTA 5K24A 2Y96A 1L8GA 1AAXA 1ZZWA 2CM7A 4Z6BA 3QCEA 1PA1A 2CNGA 2I3UA 4KYQA 3SR9A 1NWEA 2VEWA 1G1FA 2OZ5A 3QCHA 2HCMA 4NWGA 2QCJA 1GWZA 3QCGA 2MBCA 2BV5A 3ZM3A 2H4KA 1C84A 2SHPA 3F81A 3S3HA 1XXPA 1YGUA 3I80A 2QDCA 2BZLA 5K22A 3I7ZA 4GE2A 2F6WA 4H1OA 2B49A 3F9BA 2B4SA 3ZV2A 3BLUA 1XM2A 2GWOA 2GJTA 4BPCA 2P4DA 2VEXA 3BRHA 4WTYA 4Y14A 5KACA 2I5XA 3AWGA 1G1HA 3H2XA 1PXHA 1PA9A 5KA3A 1U26A 3NMEA 3O5XA 1OETA 2FH7A 1XRIA 3QKQA 2I1YA 1R6HA
chains in the Genus database with same CATH superfamily
3QCCA 3EAXA 1I9SA 4QAHA 4QDIA 1ECVA 4RKKA 3F41A 5A5FA 3AWEA 2I4GA 2B4OA 2H4GA 3SMEA 3D42A 4JMJA 2WGPA 1VHRA 2QDPA 1T48A 5KA4A 4RI4A 1C86A 4R30A 5LXQB 4OHDA 4RHGA 2Y1OA 1ONZA 1YWFA 3ZM6A 1PTTA 3HN7A 1PTVA 3QCLA 2HNPA 4ICZA 2HXPA 3BM8A 5BZXA 1GQQA 4JNBA 2RF6A 2JFFA 2I75A 4QF5A 2VEUA 2B4UA 1LYVA 2F6FA 4D3QA 2F6ZA 1OHDA 1LQFA 3ZL8A 4HJQA 1V3AA 3I36A 4PYHA 2P6XA 1JF7A 4R0SA 1J4XA 1G4WR 3B7OA 2I4EA 2CMAA 4OHLA 1L8KA 2NZ6A 2GC5A 2GP0A 1G7FA 3EZZA 3QCIA 1A5YA 1YPTA 4IKCA 1YN9A 1G4US 3QCBA 3V0HA 4NX8A 1EENA 2H03A 2QBPA 2G6ZA 2I6JA 1I57A 2CNEA 1OEVA 1WRMA 2JFHA 5BUGA 2Q05A 1ONYA 3PYZA 1QZ0A 2PI7A 1C87A 1O5ZA 1G1GA 2QEPA 2B4PA 3D1HA 4BUCA 2CMBA 3U96A 1PYNA 1P3DA 1ZCLA 4WOHA 2H4VA 4MBBA 4S0GA 2F6TA 2I6OA 2J16B 1P15A 5EHRA 1QXKA 1GG4A 4D3PA 3S3FA 1OEMX 4GWFA 1Q6JA 5EHPA 3CM3A 2E0TA 2I6PA 3QCFA 2M3VA 3ZM5A 4CVKA 2H04A 1LARA 2AM2A 1OHCA 2XPCA 1KAVA 3UAGA 3F99A 2JJDA 3V0JA 3OMHA 4NNDA 3V0EA 5KA0A 2HC2A 4ZI4A 2Y2FA 3QCJA 5IBSA 1RPMA 1GFYA 4Y2EA 3EB1A 4RH9A 5I6VA 2VORA 3F9AA 2WJPA 4QAPA 1ZCKA 5GTJA 3S3EA 1U25A 2HVLA 3V0FA 3N2AA 1C83A 2I6MA 2NV5A 3V0GA 1PTUA 4OHHA 4KI9A 4GS0A 2OC3A 3EU0A 3MMJA 4WU2A 1E8CA 2ESBA 1OEOX 2QBRA 4GE5A 1Q6NA 5K9WA 2Y67A 3OLRA 1SUGA 4QBEA 1OESA 1OEUA 3RGQA 4C13A 1C85A 1FPZA 5KA8A 3S4OA 3EMUA 2F70A 2QCTA 2CMCA 4R0TA 3ZM2A 3LJ8A 2XJAA 4WU3A 5K25A 2F6VA 4D3RA 1PTYA 3ZM0A 1WCHA 1FQ1A 5AWXA 1Q6SA 2PQ5A 5KA7A 3AWFA 2CM2A 3S4EA 3V0IA 4DGXA 4JBCA 4RI5A 4JMKA 2FJMA 2ZN7A 1U24A 3QCKA 2HC1A 2I6IA 3NRSA 2PSZA 1OHEA 4NYHA 3N0AA 3S3KA 4I8NA 1W7KA 1C88A 2J17A 4RH5A 1P31A 5IBMA 3CWEA 5BZZA 3QCMA 2PA5A 5KADA 2BGDA 3M4UA 4YAAA 5KAAA 1G7GA 2UAGA 2J16A 1BZJA 3D9CA 1EEHA 5KABA 2OUDA 2A3KA 2QDMA 4J51A 4OHIA 2VEYA 2NT7A 2QBQA 1ZC0A 2JFGA 5K23A 5MMZB 2BGEA 2GC6A 3RGOA 3O3LA 3A5JA 3GXGA 2G59A 4GRZA 1NO6A 2PBNA 4HJPA 3O4TA 5HDEA 4HV4A 2CNIA 1E0DA 4GRYA 2QBSA 1YGRA 5J8RA 3ZMPA 2R0BA 2C46A 1RXDA 2ZMMA 1FGSA 2C7SA 2GCAA 4NWFA 2F6YA 4BJOA 1Q6MA 2IMGA 2B07A 5K9VA 4ERCA 5BX1A 1J6UA 2Q47A 4KYRA 3MOZA 3ZMQA 3O4SA 2CJZA 2HNQA 3RO1A 4HRFA 1KAKA 2FJNA 2NT2A 3QCNA 5KA1A 3V0DA 2B3OA 3QCDA 4DGPA 3BLTA 4ZIYA 5A5EA 2PT0A 4C12A 2CNFA 3MOWA 5KA9A 4B04A 4GFUA 1I9TA 2CM8A 3RZ2A 3ZM1A 5KA2A 2NTAA 1YTWA 2AZRA 4H34A 1MKPA 1YTNA 1EEOA 4RDDA 1Q6PA 2F46A 2HY3A 2YDUA 1T4JA 2F71A 2VTDA 1T49A 2DXPA 2CM3A 4YR8B 4BUBA 1JBWA 3O4UA 4GE6A 2BIJA 1NWLA 2I42A 2VEVA 1XBOA 3PS5A 1Q6TA 3D1QA 3D1OA 2I4HA 4AZ1A 3D44A 1Q1MA 1WAXA 1PH0A 1XXVA 2F00A 2X5OA 1M3GA 2UUPA 2I3RA 2AHSA 3MVNA 2HB1A 1YZ4A 4TVVA 1X24A 3GXHA 1BZCA 2Y66A 2CFVA 2NLKA 3LK7A 2AM1A 4OHEA 1YTSA 2A8BA 2OOQA 1NZ7A 1D5RA 4QUMA 4ZN5A 4QUNA 5M43A 4QBWA 4PVGA 1FPRA 2H02A 3A5KA 1BZHA 1YFOA 3QKPA 4GFVA 1NNYA 2CNHA 1JLNA 1NL9A 4ZRTA 5K24A 1JBVA 2Y96A 2VOSA 1L8GA 1AAXA 1ZZWA 2CM7A 3QCZA 4Z6BA 1W78A 3QCEA 1PA1A 2CNGA 2I3UA 4KYQA 3SR9A 1NWEA 2VEWA 2GCBA 1G1FA 2OZ5A 3QCHA 4CVMA 2Y68A 2HCMA 4NWGA 2QCJA 1GWZA 2WTZA 3QCGA 2MBCA 2BV5A 3ZM3A 1GQYA 2H4KA 1C84A 2SHPA 3F81A 3S3HA 1XXPA 1YGUA 4UAGA 3I80A 2QDCA 2BZLA 5K22A 3I7ZA 4CVLA 4GE2A 2F6WA 4H1OA 2B49A 3F9BA 2B4SA 3ZV2A 3BLUA 1XM2A 2GWOA 2GJTA 4BPCA 2P4DA 2VEXA 3BRHA 4WTYA 4Y14A 5KACA 1UAGA 2I5XA 3AWGA 1G1HA 3H2XA 1PXHA 1PA9A 2UUOA 5KA3A 1U26A 3NMEA 3O5XA 1OETA 2FH7A 2VTEA 1XRIA 3QKQA 2I1YA 1R6HA
chains in the Genus database with same CATH topology
3QCCA 3EAXA 1I9SA 4QAHA 1ECVA 4RKKA 3F41A 3AWEA 2I4GA 2B4OA 2H4GA 3SMEA 3D42A 4JMJA 2WGPA 1VHRA 2QDPA 1T48A 5KA4A 4RI4A 1C86A 4R30A 5LXQB 4OHDA 4RHGA 1ONZA 1YWFA 1PTTA 1PTVA 3QCLA 2HNPA 4ICZA 2HXPA 3BM8A 5BZXA 4JNBA 2RF6A 2I75A 2VEUA 2B4UA 1LYVA 2F6FA 4D3QA 2F6ZA 1OHDA 1LQFA 4HJQA 1V3AA 3I36A 4PYHA 2P6XA 1JF7A 4R0SA 1J4XA 1G4WR 3B7OA 2I4EA 2CMAA 4OHLA 1L8KA 2NZ6A 2GP0A 1G7FA 3EZZA 3QCIA 1A5YA 1YPTA 4IKCA 1YN9A 1G4US 3QCBA 3V0HA 4NX8A 1EENA 2H03A 2QBPA 2G6ZA 2I6JA 1I57A 2CNEA 1OEVA 1WRMA 5BUGA 2Q05A 1ONYA 1QZ0A 2PI7A 1C87A 1G1GA 2QEPA 2B4PA 3D1HA 2CMBA 3U96A 1PYNA 1ZCLA 4WOHA 2H4VA 4MBBA 4S0GA 2F6TA 2I6OA 2J16B 1P15A 5EHRA 1QXKA 4D3PA 3S3FA 1OEMX 4GWFA 1Q6JA 5EHPA 3CM3A 2E0TA 2I6PA 3QCFA 2M3VA 2H04A 1LARA 1OHCA 1KAVA 3F99A 2JJDA 3V0JA 3OMHA 4NNDA 3V0EA 5KA0A 2HC2A 4ZI4A 2Y2FA 3QCJA 5IBSA 1RPMA 1GFYA 4Y2EA 3EB1A 4RH9A 5I6VA 3F9AA 4QAPA 1ZCKA 5GTJA 3S3EA 1U25A 2HVLA 3V0FA 1C83A 2I6MA 2NV5A 3V0GA 1PTUA 4OHHA 4KI9A 4GS0A 2OC3A 3EU0A 3MMJA 4WU2A 2ESBA 1OEOX 2QBRA 4GE5A 1Q6NA 5K9WA 4QBEA 3OLRA 1SUGA 1OESA 1OEUA 3RGQA 1C85A 1FPZA 5KA8A 3S4OA 3EMUA 2F70A 2QCTA 2CMCA 4R0TA 3ZM2A 3LJ8A 4WU3A 5K25A 2F6VA 4D3RA 1PTYA 3ZM0A 1WCHA 1FQ1A 5AWXA 1Q6SA 2PQ5A 5KA7A 3AWFA 2CM2A 3S4EA 3V0IA 4DGXA 4JBCA 4RI5A 4JMKA 2FJMA 2ZN7A 1U24A 3QCKA 2HC1A 2I6IA 2PSZA 1OHEA 4NYHA 3N0AA 3S3KA 4I8NA 1C88A 2J17A 4RH5A 5IBMA 3CWEA 5BZZA 3QCMA 2PA5A 5KADA 2BGDA 3M4UA 4YAAA 5KAAA 1G7GA 2J16A 1BZJA 3D9CA 5KABA 2OUDA 2A3KA 2QDMA 4J51A 4OHIA 2VEYA 2NT7A 2QBQA 1ZC0A 5K23A 5MMZB 2BGEA 3RGOA 3O3LA 3A5JA 3GXGA 2G59A 4GRZA 1NO6A 2PBNA 4HJPA 3O4TA 5HDEA 2CNIA 4GRYA 2QBSA 1YGRA 5J8RA 3ZMPA 2R0BA 2C46A 1RXDA 2ZMMA 2C7SA 4NWFA 2F6YA 4BJOA 1Q6MA 2IMGA 2B07A 5K9VA 4ERCA 5BX1A 2Q47A 4KYRA 3MOZA 3ZMQA 3O4SA 2CJZA 2HNQA 3RO1A 4HRFA 1KAKA 2FJNA 2NT2A 3QCNA 5KA1A 3V0DA 2B3OA 3QCDA 4DGPA 3BLTA 2PT0A 2CNFA 3MOWA 5KA9A 4B04A 4GFUA 1I9TA 2CM8A 3RZ2A 3ZM1A 5KA2A 2NTAA 1YTWA 2AZRA 4H34A 1MKPA 1YTNA 1EEOA 4RDDA 1Q6PA 2F46A 2HY3A 2YDUA 1T4JA 2F71A 1T49A 2DXPA 2CM3A 4YR8B 3O4UA 4GE6A 2BIJA 1NWLA 2I42A 2VEVA 1XBOA 3PS5A 1Q6TA 3D1QA 3D1OA 2I4HA 4AZ1A 3D44A 1Q1MA 1WAXA 1PH0A 1XXVA 1M3GA 2I3RA 2AHSA 2HB1A 1YZ4A 4TVVA 1X24A 3GXHA 1BZCA 2CFVA 2NLKA 4OHEA 1YTSA 2A8BA 2OOQA 1NZ7A 1D5RA 4QUMA 4ZN5A 4QUNA 5M43A 4QBWA 4PVGA 1FPRA 2H02A 3A5KA 1BZHA 1YFOA 3QKPA 4GFVA 1NNYA 2CNHA 1JLNA 1NL9A 4ZRTA 5K24A 2Y96A 1L8GA 1AAXA 1ZZWA 2CM7A 4Z6BA 3QCEA 1PA1A 2CNGA 2I3UA 4KYQA 3SR9A 1NWEA 2VEWA 1G1FA 2OZ5A 3QCHA 2HCMA 4NWGA 2QCJA 1GWZA 3QCGA 2MBCA 2BV5A 3ZM3A 2H4KA 1C84A 2SHPA 3F81A 3S3HA 1XXPA 1YGUA 3I80A 2QDCA 2BZLA 5K22A 3I7ZA 4GE2A 2F6WA 4H1OA 2B49A 3F9BA 2B4SA 3ZV2A 3BLUA 1XM2A 2GWOA 2GJTA 4BPCA 2P4DA 2VEXA 3BRHA 4WTYA 4Y14A 5KACA 2I5XA 3AWGA 1G1HA 3H2XA 1PXHA 1PA9A 5KA3A 1U26A 3NMEA 3O5XA 1OETA 2FH7A 1XRIA 3QKQA 2I1YA 1R6HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCC A;  3EAX A;  1I9S A;  4QAH A;  1ECV A;  4RKK A;  3F41 A;  3AWE A;  2I4G A;  2B4O A;  2H4G A;  3SME A;  3D42 A;  4JMJ A;  2WGP A;  1VHR A;  2QDP A;  1T48 A;  5KA4 A;  4RI4 A;  1C86 A;  4R30 A;  5LXQ B;  4OHD A;  4RHG A;  1ONZ A;  1YWF A;  1PTT A;  1PTV A;  3QCL A;  2HNP A;  4ICZ A;  2HXP A;  3BM8 A;  5BZX A;  4JNB A;  2RF6 A;  2I75 A;  2VEU A;  2B4U A;  1LYV A;  2F6F A;  4D3Q A;  2F6Z A;  1OHD A;  1LQF A;  4HJQ A;  1V3A A;  3I36 A;  4PYH A;  2P6X A;  1JF7 A;  4R0S A;  1J4X A;  1G4W R;  3B7O A;  2I4E A;  2CMA A;  4OHL A;  1L8K A;  2NZ6 A;  2GP0 A;  1G7F A;  3EZZ A;  3QCI A;  1A5Y A;  1YPT A;  4IKC A;  1YN9 A;  1G4U S;  3QCB A;  3V0H A;  4NX8 A;  1EEN A;  2H03 A;  2QBP A;  2G6Z A;  2I6J A;  1I57 A;  2CNE A;  1OEV A;  1WRM A;  5BUG A;  2Q05 A;  1ONY A;  1QZ0 A;  2PI7 A;  1C87 A;  1G1G A;  2QEP A;  2B4P A;  3D1H A;  2CMB A;  3U96 A;  1PYN A;  1ZCL A;  4WOH A;  2H4V A;  4MBB A;  4S0G A;  2F6T A;  2I6O A;  2J16 B;  1P15 A;  5EHR A;  1QXK A;  4D3P A;  3S3F A;  1OEM X;  4GWF A;  1Q6J A;  5EHP A;  3CM3 A;  2E0T A;  2I6P A;  3QCF A;  2M3V A;  2H04 A;  1LAR A;  1OHC A;  1KAV A;  3F99 A;  2JJD A;  3V0J A;  3OMH A;  4NND A;  3V0E A;  5KA0 A;  2HC2 A;  4ZI4 A;  2Y2F A;  3QCJ A;  5IBS A;  1RPM A;  1GFY A;  4Y2E A;  3EB1 A;  4RH9 A;  5I6V A;  3F9A A;  4QAP A;  1ZCK A;  5GTJ A;  3S3E A;  1U25 A;  2HVL A;  3V0F A;  1C83 A;  2I6M A;  2NV5 A;  3V0G A;  1PTU A;  4OHH A;  4KI9 A;  4GS0 A;  2OC3 A;  3EU0 A;  3MMJ A;  4WU2 A;  2ESB A;  1OEO X;  2QBR A;  4GE5 A;  1Q6N A;  5K9W A;  4QBE A;  3OLR A;  1SUG A;  1OES A;  1OEU A;  3RGQ A;  1C85 A;  1FPZ A;  5KA8 A;  3S4O A;  3EMU A;  2F70 A;  2QCT A;  2CMC A;  4R0T A;  3ZM2 A;  3LJ8 A;  4WU3 A;  5K25 A;  2F6V A;  4D3R A;  1PTY A;  3ZM0 A;  1WCH A;  1FQ1 A;  5AWX A;  1Q6S A;  2PQ5 A;  5KA7 A;  3AWF A;  2CM2 A;  3S4E A;  3V0I A;  4DGX A;  4JBC A;  4RI5 A;  4JMK A;  2FJM A;  2ZN7 A;  1U24 A;  3QCK A;  2HC1 A;  2I6I A;  2PSZ A;  1OHE A;  4NYH A;  3N0A A;  3S3K A;  4I8N A;  1C88 A;  2J17 A;  4RH5 A;  5IBM A;  3CWE A;  5BZZ A;  3QCM A;  2PA5 A;  5KAD A;  2BGD A;  3M4U A;  4YAA A;  5KAA A;  1G7G A;  2J16 A;  1BZJ A;  3D9C A;  5KAB A;  2OUD A;  2A3K A;  2QDM A;  4J51 A;  4OHI A;  2VEY A;  2NT7 A;  2QBQ A;  1ZC0 A;  5K23 A;  5MMZ B;  2BGE A;  3RGO A;  3O3L A;  3A5J A;  3GXG A;  2G59 A;  4GRZ A;  1NO6 A;  2PBN A;  4HJP A;  3O4T A;  5HDE A;  2CNI A;  4GRY A;  2QBS A;  1YGR A;  5J8R A;  3ZMP A;  2R0B A;  2C46 A;  1RXD A;  2ZMM A;  2C7S A;  4NWF A;  2F6Y A;  4BJO A;  1Q6M A;  2IMG A;  2B07 A;  5K9V A;  4ERC A;  5BX1 A;  2Q47 A;  4KYR A;  3MOZ A;  3ZMQ A;  3O4S A;  2CJZ A;  2HNQ A;  3RO1 A;  4HRF A;  1KAK A;  2FJN A;  2NT2 A;  3QCN A;  5KA1 A;  3V0D A;  2B3O A;  3QCD A;  4DGP A;  3BLT A;  2PT0 A;  2CNF A;  3MOW A;  5KA9 A;  4B04 A;  4GFU A;  1I9T A;  2CM8 A;  3RZ2 A;  3ZM1 A;  5KA2 A;  2NTA A;  1YTW A;  2AZR A;  4H34 A;  1MKP A;  1YTN A;  1EEO A;  4RDD A;  1Q6P A;  2F46 A;  2HY3 A;  2YDU A;  1T4J A;  2F71 A;  1T49 A;  2DXP A;  2CM3 A;  4YR8 B;  3O4U A;  4GE6 A;  2BIJ A;  1NWL A;  2I42 A;  2VEV A;  1XBO A;  3PS5 A;  1Q6T A;  3D1Q A;  3D1O A;  2I4H A;  4AZ1 A;  3D44 A;  1Q1M A;  1WAX A;  1PH0 A;  1XXV A;  1M3G A;  2I3R A;  2AHS A;  2HB1 A;  1YZ4 A;  4TVV A;  1X24 A;  3GXH A;  1BZC A;  2CFV A;  2NLK A;  4OHE A;  1YTS A;  2A8B A;  2OOQ A;  1NZ7 A;  1D5R A;  4QUM A;  4ZN5 A;  4QUN A;  5M43 A;  4QBW A;  4PVG A;  1FPR A;  2H02 A;  3A5K A;  1BZH A;  1YFO A;  3QKP A;  4GFV A;  1NNY A;  2CNH A;  1JLN A;  1NL9 A;  4ZRT A;  5K24 A;  2Y96 A;  1L8G A;  1AAX A;  1ZZW A;  2CM7 A;  4Z6B A;  3QCE A;  1PA1 A;  2CNG A;  2I3U A;  4KYQ A;  3SR9 A;  1NWE A;  2VEW A;  1G1F A;  2OZ5 A;  3QCH A;  2HCM A;  4NWG A;  2QCJ A;  1GWZ A;  3QCG A;  2MBC A;  2BV5 A;  3ZM3 A;  2H4K A;  1C84 A;  2SHP A;  3F81 A;  3S3H A;  1XXP A;  1YGU A;  3I80 A;  2QDC A;  2BZL A;  5K22 A;  3I7Z A;  4GE2 A;  2F6W A;  4H1O A;  2B49 A;  3F9B A;  2B4S A;  3ZV2 A;  3BLU A;  1XM2 A;  2GWO A;  2GJT A;  4BPC A;  2P4D A;  2VEX A;  3BRH A;  4WTY A;  4Y14 A;  5KAC A;  2I5X A;  3AWG A;  1G1H A;  3H2X A;  1PXH A;  1PA9 A;  5KA3 A;  1U26 A;  3NME A;  3O5X A;  1OET A;  2FH7 A;  1XRI A;  3QKQ A;  2I1Y A;  1R6H A; 
#chains in the Genus database with same CATH topology
 3QCC A;  3EAX A;  1I9S A;  4QAH A;  4QDI A;  1ECV A;  4RKK A;  3F41 A;  5A5F A;  3AWE A;  2I4G A;  2B4O A;  2H4G A;  3SME A;  3D42 A;  4JMJ A;  2WGP A;  1VHR A;  2QDP A;  1T48 A;  5KA4 A;  4RI4 A;  1C86 A;  4R30 A;  5LXQ B;  4OHD A;  4RHG A;  2Y1O A;  1ONZ A;  1YWF A;  3ZM6 A;  1PTT A;  3HN7 A;  1PTV A;  3QCL A;  2HNP A;  4ICZ A;  2HXP A;  3BM8 A;  5BZX A;  1GQQ A;  4JNB A;  2RF6 A;  2JFF A;  2I75 A;  4QF5 A;  2VEU A;  2B4U A;  1LYV A;  2F6F A;  4D3Q A;  2F6Z A;  1OHD A;  1LQF A;  3ZL8 A;  4HJQ A;  1V3A A;  3I36 A;  4PYH A;  2P6X A;  1JF7 A;  4R0S A;  1J4X A;  1G4W R;  3B7O A;  2I4E A;  2CMA A;  4OHL A;  1L8K A;  2NZ6 A;  2GC5 A;  2GP0 A;  1G7F A;  3EZZ A;  3QCI A;  1A5Y A;  1YPT A;  4IKC A;  1YN9 A;  1G4U S;  3QCB A;  3V0H A;  4NX8 A;  1EEN A;  2H03 A;  2QBP A;  2G6Z A;  2I6J A;  1I57 A;  2CNE A;  1OEV A;  1WRM A;  2JFH A;  5BUG A;  2Q05 A;  1ONY A;  3PYZ A;  1QZ0 A;  2PI7 A;  1C87 A;  1O5Z A;  1G1G A;  2QEP A;  2B4P A;  3D1H A;  4BUC A;  2CMB A;  3U96 A;  1PYN A;  1P3D A;  1ZCL A;  4WOH A;  2H4V A;  4MBB A;  4S0G A;  2F6T A;  2I6O A;  2J16 B;  1P15 A;  5EHR A;  1QXK A;  1GG4 A;  4D3P A;  3S3F A;  1OEM X;  4GWF A;  1Q6J A;  5EHP A;  3CM3 A;  2E0T A;  2I6P A;  3QCF A;  2M3V A;  3ZM5 A;  4CVK A;  2H04 A;  1LAR A;  2AM2 A;  1OHC A;  2XPC A;  1KAV A;  3UAG A;  3F99 A;  2JJD A;  3V0J A;  3OMH A;  4NND A;  3V0E A;  5KA0 A;  2HC2 A;  4ZI4 A;  2Y2F A;  3QCJ A;  5IBS A;  1RPM A;  1GFY A;  4Y2E A;  3EB1 A;  4RH9 A;  5I6V A;  2VOR A;  3F9A A;  2WJP A;  4QAP A;  1ZCK A;  5GTJ A;  3S3E A;  1U25 A;  2HVL A;  3V0F A;  3N2A A;  1C83 A;  2I6M A;  2NV5 A;  3V0G A;  1PTU A;  4OHH A;  4KI9 A;  4GS0 A;  2OC3 A;  3EU0 A;  3MMJ A;  4WU2 A;  1E8C A;  2ESB A;  1OEO X;  2QBR A;  4GE5 A;  1Q6N A;  5K9W A;  2Y67 A;  3OLR A;  1SUG A;  4QBE A;  1OES A;  1OEU A;  3RGQ A;  4C13 A;  1C85 A;  1FPZ A;  5KA8 A;  3S4O A;  3EMU A;  2F70 A;  2QCT A;  2CMC A;  4R0T A;  3ZM2 A;  3LJ8 A;  2XJA A;  4WU3 A;  5K25 A;  2F6V A;  4D3R A;  1PTY A;  3ZM0 A;  1WCH A;  1FQ1 A;  5AWX A;  1Q6S A;  2PQ5 A;  5KA7 A;  3AWF A;  2CM2 A;  3S4E A;  3V0I A;  4DGX A;  4JBC A;  4RI5 A;  4JMK A;  2FJM A;  2ZN7 A;  1U24 A;  3QCK A;  2HC1 A;  2I6I A;  3NRS A;  2PSZ A;  1OHE A;  4NYH A;  3N0A A;  3S3K A;  4I8N A;  1W7K A;  1C88 A;  2J17 A;  4RH5 A;  1P31 A;  5IBM A;  3CWE A;  5BZZ A;  3QCM A;  2PA5 A;  5KAD A;  2BGD A;  3M4U A;  4YAA A;  5KAA A;  1G7G A;  2UAG A;  2J16 A;  1BZJ A;  3D9C A;  1EEH A;  5KAB A;  2OUD A;  2A3K A;  2QDM A;  4J51 A;  4OHI A;  2VEY A;  2NT7 A;  2QBQ A;  1ZC0 A;  2JFG A;  5K23 A;  5MMZ B;  2BGE A;  2GC6 A;  3RGO A;  3O3L A;  3A5J A;  3GXG A;  2G59 A;  4GRZ A;  1NO6 A;  2PBN A;  4HJP A;  3O4T A;  5HDE A;  4HV4 A;  2CNI A;  1E0D A;  4GRY A;  2QBS A;  1YGR A;  5J8R A;  3ZMP A;  2R0B A;  2C46 A;  1RXD A;  2ZMM A;  1FGS A;  2C7S A;  2GCA A;  4NWF A;  2F6Y A;  4BJO A;  1Q6M A;  2IMG A;  2B07 A;  5K9V A;  4ERC A;  5BX1 A;  1J6U A;  2Q47 A;  4KYR A;  3MOZ A;  3ZMQ A;  3O4S A;  2CJZ A;  2HNQ A;  3RO1 A;  4HRF A;  1KAK A;  2FJN A;  2NT2 A;  3QCN A;  5KA1 A;  3V0D A;  2B3O A;  3QCD A;  4DGP A;  3BLT A;  4ZIY A;  5A5E A;  2PT0 A;  4C12 A;  2CNF A;  3MOW A;  5KA9 A;  4B04 A;  4GFU A;  1I9T A;  2CM8 A;  3RZ2 A;  3ZM1 A;  5KA2 A;  2NTA A;  1YTW A;  2AZR A;  4H34 A;  1MKP A;  1YTN A;  1EEO A;  4RDD A;  1Q6P A;  2F46 A;  2HY3 A;  2YDU A;  1T4J A;  2F71 A;  2VTD A;  1T49 A;  2DXP A;  2CM3 A;  4YR8 B;  4BUB A;  1JBW A;  3O4U A;  4GE6 A;  2BIJ A;  1NWL A;  2I42 A;  2VEV A;  1XBO A;  3PS5 A;  1Q6T A;  3D1Q A;  3D1O A;  2I4H A;  4AZ1 A;  3D44 A;  1Q1M A;  1WAX A;  1PH0 A;  1XXV A;  2F00 A;  2X5O A;  1M3G A;  2UUP A;  2I3R A;  2AHS A;  3MVN A;  2HB1 A;  1YZ4 A;  4TVV A;  1X24 A;  3GXH A;  1BZC A;  2Y66 A;  2CFV A;  2NLK A;  3LK7 A;  2AM1 A;  4OHE A;  1YTS A;  2A8B A;  2OOQ A;  1NZ7 A;  1D5R A;  4QUM A;  4ZN5 A;  4QUN A;  5M43 A;  4QBW A;  4PVG A;  1FPR A;  2H02 A;  3A5K A;  1BZH A;  1YFO A;  3QKP A;  4GFV A;  1NNY A;  2CNH A;  1JLN A;  1NL9 A;  4ZRT A;  5K24 A;  1JBV A;  2Y96 A;  2VOS A;  1L8G A;  1AAX A;  1ZZW A;  2CM7 A;  3QCZ A;  4Z6B A;  1W78 A;  3QCE A;  1PA1 A;  2CNG A;  2I3U A;  4KYQ A;  3SR9 A;  1NWE A;  2VEW A;  2GCB A;  1G1F A;  2OZ5 A;  3QCH A;  4CVM A;  2Y68 A;  2HCM A;  4NWG A;  2QCJ A;  1GWZ A;  2WTZ A;  3QCG A;  2MBC A;  2BV5 A;  3ZM3 A;  1GQY A;  2H4K A;  1C84 A;  2SHP A;  3F81 A;  3S3H A;  1XXP A;  1YGU A;  4UAG A;  3I80 A;  2QDC A;  2BZL A;  5K22 A;  3I7Z A;  4CVL A;  4GE2 A;  2F6W A;  4H1O A;  2B49 A;  3F9B A;  2B4S A;  3ZV2 A;  3BLU A;  1XM2 A;  2GWO A;  2GJT A;  4BPC A;  2P4D A;  2VEX A;  3BRH A;  4WTY A;  4Y14 A;  5KAC A;  1UAG A;  2I5X A;  3AWG A;  1G1H A;  3H2X A;  1PXH A;  1PA9 A;  2UUO A;  5KA3 A;  1U26 A;  3NME A;  3O5X A;  1OET A;  2FH7 A;  2VTE A;  1XRI A;  3QKQ A;  2I1Y A;  1R6H A; 
#chains in the Genus database with same CATH homology
 3QCC A;  3EAX A;  1I9S A;  4QAH A;  1ECV A;  4RKK A;  3F41 A;  3AWE A;  2I4G A;  2B4O A;  2H4G A;  3SME A;  3D42 A;  4JMJ A;  2WGP A;  1VHR A;  2QDP A;  1T48 A;  5KA4 A;  4RI4 A;  1C86 A;  4R30 A;  5LXQ B;  4OHD A;  4RHG A;  1ONZ A;  1YWF A;  1PTT A;  1PTV A;  3QCL A;  2HNP A;  4ICZ A;  2HXP A;  3BM8 A;  5BZX A;  4JNB A;  2RF6 A;  2I75 A;  2VEU A;  2B4U A;  1LYV A;  2F6F A;  4D3Q A;  2F6Z A;  1OHD A;  1LQF A;  4HJQ A;  1V3A A;  3I36 A;  4PYH A;  2P6X A;  1JF7 A;  4R0S A;  1J4X A;  1G4W R;  3B7O A;  2I4E A;  2CMA A;  4OHL A;  1L8K A;  2NZ6 A;  2GP0 A;  1G7F A;  3EZZ A;  3QCI A;  1A5Y A;  1YPT A;  4IKC A;  1YN9 A;  1G4U S;  3QCB A;  3V0H A;  4NX8 A;  1EEN A;  2H03 A;  2QBP A;  2G6Z A;  2I6J A;  1I57 A;  2CNE A;  1OEV A;  1WRM A;  5BUG A;  2Q05 A;  1ONY A;  1QZ0 A;  2PI7 A;  1C87 A;  1G1G A;  2QEP A;  2B4P A;  3D1H A;  2CMB A;  3U96 A;  1PYN A;  1ZCL A;  4WOH A;  2H4V A;  4MBB A;  4S0G A;  2F6T A;  2I6O A;  2J16 B;  1P15 A;  5EHR A;  1QXK A;  4D3P A;  3S3F A;  1OEM X;  4GWF A;  1Q6J A;  5EHP A;  3CM3 A;  2E0T A;  2I6P A;  3QCF A;  2M3V A;  2H04 A;  1LAR A;  1OHC A;  1KAV A;  3F99 A;  2JJD A;  3V0J A;  3OMH A;  4NND A;  3V0E A;  5KA0 A;  2HC2 A;  4ZI4 A;  2Y2F A;  3QCJ A;  5IBS A;  1RPM A;  1GFY A;  4Y2E A;  3EB1 A;  4RH9 A;  5I6V A;  3F9A A;  4QAP A;  1ZCK A;  5GTJ A;  3S3E A;  1U25 A;  2HVL A;  3V0F A;  1C83 A;  2I6M A;  2NV5 A;  3V0G A;  1PTU A;  4OHH A;  4KI9 A;  4GS0 A;  2OC3 A;  3EU0 A;  3MMJ A;  4WU2 A;  2ESB A;  1OEO X;  2QBR A;  4GE5 A;  1Q6N A;  5K9W A;  4QBE A;  3OLR A;  1SUG A;  1OES A;  1OEU A;  3RGQ A;  1C85 A;  1FPZ A;  5KA8 A;  3S4O A;  3EMU A;  2F70 A;  2QCT A;  2CMC A;  4R0T A;  3ZM2 A;  3LJ8 A;  4WU3 A;  5K25 A;  2F6V A;  4D3R A;  1PTY A;  3ZM0 A;  1WCH A;  1FQ1 A;  5AWX A;  1Q6S A;  2PQ5 A;  5KA7 A;  3AWF A;  2CM2 A;  3S4E A;  3V0I A;  4DGX A;  4JBC A;  4RI5 A;  4JMK A;  2FJM A;  2ZN7 A;  1U24 A;  3QCK A;  2HC1 A;  2I6I A;  2PSZ A;  1OHE A;  4NYH A;  3N0A A;  3S3K A;  4I8N A;  1C88 A;  2J17 A;  4RH5 A;  5IBM A;  3CWE A;  5BZZ A;  3QCM A;  2PA5 A;  5KAD A;  2BGD A;  3M4U A;  4YAA A;  5KAA A;  1G7G A;  2J16 A;  1BZJ A;  3D9C A;  5KAB A;  2OUD A;  2A3K A;  2QDM A;  4J51 A;  4OHI A;  2VEY A;  2NT7 A;  2QBQ A;  1ZC0 A;  5K23 A;  5MMZ B;  2BGE A;  3RGO A;  3O3L A;  3A5J A;  3GXG A;  2G59 A;  4GRZ A;  1NO6 A;  2PBN A;  4HJP A;  3O4T A;  5HDE A;  2CNI A;  4GRY A;  2QBS A;  1YGR A;  5J8R A;  3ZMP A;  2R0B A;  2C46 A;  1RXD A;  2ZMM A;  2C7S A;  4NWF A;  2F6Y A;  4BJO A;  1Q6M A;  2IMG A;  2B07 A;  5K9V A;  4ERC A;  5BX1 A;  2Q47 A;  4KYR A;  3MOZ A;  3ZMQ A;  3O4S A;  2CJZ A;  2HNQ A;  3RO1 A;  4HRF A;  1KAK A;  2FJN A;  2NT2 A;  3QCN A;  5KA1 A;  3V0D A;  2B3O A;  3QCD A;  4DGP A;  3BLT A;  2PT0 A;  2CNF A;  3MOW A;  5KA9 A;  4B04 A;  4GFU A;  1I9T A;  2CM8 A;  3RZ2 A;  3ZM1 A;  5KA2 A;  2NTA A;  1YTW A;  2AZR A;  4H34 A;  1MKP A;  1YTN A;  1EEO A;  4RDD A;  1Q6P A;  2F46 A;  2HY3 A;  2YDU A;  1T4J A;  2F71 A;  1T49 A;  2DXP A;  2CM3 A;  4YR8 B;  3O4U A;  4GE6 A;  2BIJ A;  1NWL A;  2I42 A;  2VEV A;  1XBO A;  3PS5 A;  1Q6T A;  3D1Q A;  3D1O A;  2I4H A;  4AZ1 A;  3D44 A;  1Q1M A;  1WAX A;  1PH0 A;  1XXV A;  1M3G A;  2I3R A;  2AHS A;  2HB1 A;  1YZ4 A;  4TVV A;  1X24 A;  3GXH A;  1BZC A;  2CFV A;  2NLK A;  4OHE A;  1YTS A;  2A8B A;  2OOQ A;  1NZ7 A;  1D5R A;  4QUM A;  4ZN5 A;  4QUN A;  5M43 A;  4QBW A;  4PVG A;  1FPR A;  2H02 A;  3A5K A;  1BZH A;  1YFO A;  3QKP A;  4GFV A;  1NNY A;  2CNH A;  1JLN A;  1NL9 A;  4ZRT A;  5K24 A;  2Y96 A;  1L8G A;  1AAX A;  1ZZW A;  2CM7 A;  4Z6B A;  3QCE A;  1PA1 A;  2CNG A;  2I3U A;  4KYQ A;  3SR9 A;  1NWE A;  2VEW A;  1G1F A;  2OZ5 A;  3QCH A;  2HCM A;  4NWG A;  2QCJ A;  1GWZ A;  3QCG A;  2MBC A;  2BV5 A;  3ZM3 A;  2H4K A;  1C84 A;  2SHP A;  3F81 A;  3S3H A;  1XXP A;  1YGU A;  3I80 A;  2QDC A;  2BZL A;  5K22 A;  3I7Z A;  4GE2 A;  2F6W A;  4H1O A;  2B49 A;  3F9B A;  2B4S A;  3ZV2 A;  3BLU A;  1XM2 A;  2GWO A;  2GJT A;  4BPC A;  2P4D A;  2VEX A;  3BRH A;  4WTY A;  4Y14 A;  5KAC A;  2I5X A;  3AWG A;  1G1H A;  3H2X A;  1PXH A;  1PA9 A;  5KA3 A;  1U26 A;  3NME A;  3O5X A;  1OET A;  2FH7 A;  1XRI A;  3QKQ A;  2I1Y A;  1R6H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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