2CM2A

Structure of protein tyrosine phosphatase 1b (p212121)
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
283
structure length
283
Chain Sequence
HHEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 103
structure length 283
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cm2A00
3QCBA 2NT7A 3BLTA 1ZCKA 2CMCA 1PYNA 3EMUA 2VEWA 2CNIA 3MMJA 1T48A 4RHGA 3OLRA 4GRZA 4WOHA 2QBRA 2B49A 4H1OA 2R0BA 1C83A 1WCHA 2B4UA 2NZ6A 4Y14A 1AAXA 2PA5A 1PXHA 2FH7A 4RH5A 2I1YA 1OEUA 2PI7A 1KAKA 1RPMA 2CM8A 2ZN7A 4HRFA 3ZM3A 2QBSA 2CM3A 3QCHA 4S0GA 3D1OA 4RI4A 4GS0A 1U25A 4GE2A 3V0DA 2HC1A 3ZM0A 1I57A 2NTAA 3ZM2A 4RKKA 1NL9A 5KA2A 1PA1A 2I4EA 2PT0A 2SHPA 1LYVA 1L8KA 4JMKA 1C87A 3S3EA 1C88A 4RDDA 1G1HA 2GWOA 4J51A 1FPRA 3V0FA 5EHRA 4D3RA 4OHEA 3V0GA 4BPCA 1G1FA 1WRMA 3GXGA 3EU0A 2OZ5A 4Z6BA 2IMGA 4I8NA 4YR8B 5BZZA 4JBCA 4GFUA 3S4EA 1BZJA 2F6ZA 3QCFA 1VHRA 1XM2A 4ZN5A 2P6XA 1X24A 2I6OA 2BV5A 3ZMPA 2OUDA 1A5YA 3OMHA 5KA7A 5KAAA 2NV5A 4QBEA 4R0TA 4ERCA 1RXDA 1OHEA 2F6YA 2I4HA 3QCJA 3CM3A 2QDPA 3NMEA 1EEOA 4PVGA 3CWEA 1NWEA 1I9TA 2H4GA 3EZZA 2OC3A 1C85A 2CNFA 2PQ5A 1YZ4A 2AHSA 3H2XA 3BRHA 1Q6SA 2HVLA 1G7GA 1YTNA 2NLKA 2HCMA 2J17A 1Q1MA 1MKPA 2FJMA 2BZLA 1LQFA 4GE5A 2H4KA 3O4UA 3D42A 1Q6MA 2CJZA 2I3RA 3QCMA 1J4XA 2HNQA 3I7ZA 5K9VA 2GJTA 3O3LA 4OHHA 4AZ1A 5KACA 5AWXA 2F6WA 1BZCA 4GFVA 1NWLA 1D5RA 1I9SA 1ZCLA 4QBWA 1G4WR 3D9CA 4R30A 1JLNA 2B4OA 2G59A 2HB1A 4NX8A 2Y2FA 2VEUA 3BLUA 2F46A 2QBQA 5BX1A 3QCDA 3MOZA 4ZRTA 1C86A 1JF7A 2NT2A 5IBMA 2I6JA 4DGPA 1U24A 3D1QA 4WU2A 3M4UA 2H04A 2WGPA 4GWFA 3V0IA 2H4VA 1OEMX 4QAHA 5K23A 4HJQA 3B7OA 2CM2A 2QCJA 2DXPA 1P15A 3EB1A 3O4TA 2ZMMA 2CMAA 3RZ2A 4JNBA 1QZ0A 2HXPA 1YPTA 2HY3A 2M3VA 2GP0A 3D1HA 4GRYA 1YTWA 1XBOA 5KA8A 4IKCA 2JJDA 5LXQB 2F70A 2CMBA 2HNPA 1YTSA 5K25A 4JMJA 2B4SA 3QCIA 5J8RA 5KA4A 5K24A 4BJOA 4NWFA 5K9WA 2Q05A 2A3KA 3I80A 1ONZA 2J16B 2Q47A 4KYRA 1BZHA 3LJ8A 1YGUA 1M3GA 2G6ZA 4D3QA 3O5XA 1G7FA 3V0JA 2A8BA 3RO1A 1XXVA 4QAPA 4ZI4A 5BZXA 5IBSA 1NO6A 1PH0A 2I42A 1PTTA 4OHIA 5KA1A 2CFVA 3PS5A 1Q6JA 2Y96A 4YAAA 1U26A 4H34A 3SR9A 3AWEA 2QEPA 1C84A 3QKQA 3ZMQA 2VEXA 3V0EA 5HDEA 2CNGA 3S3FA 2BIJA 2F71A 2ESBA 1R6HA 3GXHA 5GTJA 1SUGA 2HC2A 5I6VA 3QCCA 1XRIA 1GFYA 3QKPA 4R0SA 1NZ7A 2F6TA 5KA9A 1T4JA 1OEOX 1G1GA 2P4DA 1OEVA 1XXPA 1ONYA 2I6PA 2MBCA 4OHLA 1V3AA 3D44A 3S4OA 2B3OA 2VEVA 3F41A 3QCEA 3SMEA 1KAVA 2F6FA 5KABA 2I5XA 4ICZA 3MOWA 1PTUA 3N0AA 4HJPA 3RGOA 3BM8A 1YGRA 3S3KA 1LARA 3A5KA 1PA9A 1Q6TA 2OOQA 4PYHA 1PTYA 3QCKA 2B07A 1ZZWA 4B04A 2VEYA 2I4GA 4QUMA 4DGXA 2YDUA 4WU3A 5K22A 1PTVA 2H02A 3U96A 3AWFA 4NWGA 2C46A 2FJNA 2BGDA 4GE6A 1ZC0A 4WTYA 1NNYA 1OESA 4QUNA 2QCTA 5M43A 3AWGA 2E0TA 1FQ1A 2I75A 3F9BA 1L8GA 5KA0A 4D3PA 1YFOA 4RH9A 3S3HA 3ZM1A 3O4SA 3F99A 2CNHA 1EENA 1Q6NA 2QDCA 1WAXA 3I36A 5KA3A 2PBNA 2CM7A 2I6MA 3V0HA 5MMZB 4NNDA 1G4US 3F81A 4RI5A 1OHDA 4MBBA 5KADA 3RGQA 1FPZA 1YWFA 3A5JA 1OHCA 4KYQA 1Q6PA 1ECVA 1GWZA 2AZRA 4TVVA 2B4PA 3ZV2A 2RF6A 5EHPA 2C7SA 1OETA 4KI9A 2QDMA 2CNEA 3QCNA 2F6VA 4NYHA 2I6IA 2QBPA 5BUGA 3QCGA 3F9AA 3EAXA 2BGEA 2PSZA 1YN9A 4Y2EA 2I3UA 1QXKA 4OHDA 1T49A 2H03A 2J16A 3QCLA
chains in the Genus database with same CATH superfamily
3QCBA 2NT7A 3BLTA 1ZCKA 2CMCA 1PYNA 3EMUA 2VEWA 2CNIA 3MMJA 1T48A 4RHGA 3OLRA 4GRZA 4WOHA 2QBRA 2B49A 4H1OA 2R0BA 1C83A 1WCHA 2B4UA 2NZ6A 4Y14A 1AAXA 2PA5A 1PXHA 2FH7A 4RH5A 4ZIYA 2I1YA 2X5OA 1OEUA 2PI7A 1KAKA 2Y68A 1RPMA 2CM8A 2ZN7A 4HRFA 3ZM3A 2QBSA 2CM3A 3QCHA 1JBVA 4S0GA 3D1OA 4RI4A 2XPCA 4GS0A 1U25A 4GE2A 3V0DA 2HC1A 3ZM0A 1I57A 2NTAA 3ZM2A 4RKKA 1NL9A 5KA2A 1PA1A 2I4EA 2PT0A 1W78A 2SHPA 1LYVA 1L8KA 4JMKA 1C87A 3S3EA 1C88A 4RDDA 1G1HA 2XJAA 2GWOA 4J51A 1FPRA 3V0FA 5EHRA 2JFFA 3HN7A 4D3RA 4OHEA 3V0GA 4CVMA 1GQQA 1G1FA 4BPCA 1WRMA 2AM1A 3GXGA 3EU0A 2OZ5A 4Z6BA 2IMGA 4I8NA 4YR8B 5BZZA 4JBCA 4GFUA 3S4EA 1BZJA 2VOSA 2F6ZA 4HV4A 2GCBA 1VHRA 1XM2A 3QCFA 4ZN5A 2P6XA 1X24A 2I6OA 4QDIA 2BV5A 3ZMPA 2JFHA 2OUDA 2UAGA 1A5YA 3OMHA 5KA7A 5KAAA 2NV5A 4QBEA 4R0TA 4ERCA 1RXDA 4BUCA 1EEHA 1OHEA 2F6YA 2I4HA 3QCJA 3CM3A 2QDPA 3NMEA 1EEOA 4PVGA 1E8CA 3CWEA 1NWEA 1I9TA 2H4GA 3EZZA 2OC3A 1C85A 2CNFA 2PQ5A 1YZ4A 2VTDA 4UAGA 2GC5A 2AHSA 3H2XA 3BRHA 1Q6SA 2HVLA 1G7GA 1YTNA 2NLKA 2HCMA 1GG4A 2J17A 2VORA 1Q1MA 4C13A 1MKPA 2FJMA 2BZLA 1LQFA 4GE5A 2H4KA 3O4UA 3D42A 1Q6MA 2CJZA 2I3RA 3QCMA 1J4XA 1E0DA 2HNQA 3I7ZA 5K9VA 2GJTA 3O3LA 4OHHA 4AZ1A 5KACA 5AWXA 2F6WA 1BZCA 4GFVA 2WTZA 1NWLA 1D5RA 1I9SA 1ZCLA 4QBWA 1G4WR 3D9CA 4R30A 1JLNA 2B4OA 2G59A 2HB1A 4NX8A 2Y2FA 2VEUA 3BLUA 2F46A 2QBQA 5BX1A 3QCDA 3MOZA 4ZRTA 1C86A 1JF7A 2NT2A 5IBMA 2I6JA 4DGPA 1U24A 3D1QA 4WU2A 3M4UA 2H04A 2WGPA 4GWFA 1UAGA 3V0IA 2H4VA 1OEMX 4QAHA 5K23A 4HJQA 3B7OA 2CM2A 2QCJA 2DXPA 1P15A 3EB1A 3O4TA 1J6UA 2ZMMA 2CMAA 3RZ2A 4CVKA 4JNBA 1QZ0A 2HXPA 1YPTA 2HY3A 2M3VA 2GP0A 3D1HA 4GRYA 2Y66A 1YTWA 1XBOA 5KA8A 4IKCA 2JJDA 5LXQB 2F70A 2CMBA 5A5FA 2HNPA 1JBWA 1YTSA 5K25A 2GCAA 4JMJA 2B4SA 3QCIA 5J8RA 5KA4A 5K24A 4BJOA 4NWFA 5K9WA 2Q05A 2A3KA 3I80A 1ONZA 2J16B 2Q47A 4KYRA 1BZHA 3LJ8A 1YGUA 2Y1OA 1M3GA 2G6ZA 4D3QA 3O5XA 1G7FA 3V0JA 2UUPA 2A8BA 3RO1A 1XXVA 4QAPA 4ZI4A 3NRSA 5BZXA 5IBSA 1NO6A 1PH0A 2I42A 1PTTA 4OHIA 5KA1A 2CFVA 3PS5A 1Q6JA 2AM2A 2Y96A 4YAAA 3UAGA 1U26A 4H34A 3SR9A 1W7KA 2VTEA 3AWEA 2QEPA 1C84A 3QKQA 3ZMQA 2VEXA 3V0EA 5HDEA 2CNGA 3S3FA 2BIJA 2F71A 2ESBA 4QF5A 1R6HA 3GXHA 5GTJA 1SUGA 2HC2A 5I6VA 3QCCA 1XRIA 1GFYA 3QKPA 4R0SA 1NZ7A 1P31A 2F6TA 3ZM5A 5KA9A 2Y67A 1T4JA 1OEOX 1G1GA 2P4DA 1OEVA 1XXPA 1ONYA 2I6PA 2MBCA 4OHLA 1V3AA 3D44A 3S4OA 2B3OA 2VEVA 3F41A 3QCEA 3SMEA 1KAVA 2F6FA 5KABA 2I5XA 3N2AA 4ICZA 2UUOA 3MOWA 1PTUA 3N0AA 3LK7A 4HJPA 3BM8A 1YGRA 3RGOA 3S3KA 1LARA 3A5KA 1PA9A 1Q6TA 2OOQA 4PYHA 2WJPA 3MVNA 1PTYA 3QCKA 2B07A 1ZZWA 4B04A 3ZM6A 2VEYA 2I4GA 4C12A 1FGSA 4BUBA 2GC6A 4QUMA 4DGXA 2YDUA 4WU3A 5K22A 1PTVA 2H02A 5A5EA 3U96A 3AWFA 4NWGA 2C46A 2FJNA 2BGDA 4CVLA 4GE6A 1ZC0A 4WTYA 1NNYA 1OESA 3PYZA 4QUNA 2QCTA 5M43A 3AWGA 2E0TA 1FQ1A 2I75A 3F9BA 1L8GA 5KA0A 4D3PA 1YFOA 3QCZA 4RH9A 3S3HA 3ZM1A 3O4SA 3F99A 2CNHA 1EENA 1Q6NA 2QDCA 1WAXA 3I36A 5KA3A 2PBNA 2CM7A 2I6MA 3V0HA 5MMZB 4NNDA 1G4US 3F81A 1O5ZA 4RI5A 1OHDA 4MBBA 5KADA 3RGQA 1FPZA 1YWFA 3A5JA 1OHCA 4KYQA 1P3DA 1Q6PA 1ECVA 1GWZA 2AZRA 4TVVA 2B4PA 3ZV2A 2RF6A 5EHPA 2C7SA 1OETA 4KI9A 3ZL8A 1GQYA 2QDMA 2CNEA 3QCNA 2F6VA 4NYHA 2I6IA 2QBPA 5BUGA 2F00A 3QCGA 3F9AA 3EAXA 2BGEA 2JFGA 2PSZA 1YN9A 4Y2EA 2I3UA 1QXKA 4OHDA 1T49A 2H03A 2J16A 3QCLA
chains in the Genus database with same CATH topology
3QCBA 2NT7A 3BLTA 1ZCKA 2CMCA 1PYNA 3EMUA 2VEWA 2CNIA 3MMJA 1T48A 4RHGA 3OLRA 4GRZA 4WOHA 2QBRA 2B49A 4H1OA 2R0BA 1C83A 1WCHA 2B4UA 2NZ6A 4Y14A 1AAXA 2PA5A 1PXHA 2FH7A 4RH5A 2I1YA 1OEUA 2PI7A 1KAKA 1RPMA 2CM8A 2ZN7A 4HRFA 3ZM3A 2QBSA 2CM3A 3QCHA 4S0GA 3D1OA 4RI4A 4GS0A 1U25A 4GE2A 3V0DA 2HC1A 3ZM0A 1I57A 2NTAA 3ZM2A 4RKKA 1NL9A 5KA2A 1PA1A 2I4EA 2PT0A 2SHPA 1LYVA 1L8KA 4JMKA 1C87A 3S3EA 1C88A 4RDDA 1G1HA 2GWOA 4J51A 1FPRA 3V0FA 5EHRA 4D3RA 4OHEA 3V0GA 4BPCA 1G1FA 1WRMA 3GXGA 3EU0A 2OZ5A 4Z6BA 2IMGA 4I8NA 4YR8B 5BZZA 4JBCA 4GFUA 3S4EA 1BZJA 2F6ZA 3QCFA 1VHRA 1XM2A 4ZN5A 2P6XA 1X24A 2I6OA 2BV5A 3ZMPA 2OUDA 1A5YA 3OMHA 5KA7A 5KAAA 2NV5A 4QBEA 4R0TA 4ERCA 1RXDA 1OHEA 2F6YA 2I4HA 3QCJA 3CM3A 2QDPA 3NMEA 1EEOA 4PVGA 3CWEA 1NWEA 1I9TA 2H4GA 3EZZA 2OC3A 1C85A 2CNFA 2PQ5A 1YZ4A 2AHSA 3H2XA 3BRHA 1Q6SA 2HVLA 1G7GA 1YTNA 2NLKA 2HCMA 2J17A 1Q1MA 1MKPA 2FJMA 2BZLA 1LQFA 4GE5A 2H4KA 3O4UA 3D42A 1Q6MA 2CJZA 2I3RA 3QCMA 1J4XA 2HNQA 3I7ZA 5K9VA 2GJTA 3O3LA 4OHHA 4AZ1A 5KACA 5AWXA 2F6WA 1BZCA 4GFVA 1NWLA 1D5RA 1I9SA 1ZCLA 4QBWA 1G4WR 3D9CA 4R30A 1JLNA 2B4OA 2G59A 2HB1A 4NX8A 2Y2FA 2VEUA 3BLUA 2F46A 2QBQA 5BX1A 3QCDA 3MOZA 4ZRTA 1C86A 1JF7A 2NT2A 5IBMA 2I6JA 4DGPA 1U24A 3D1QA 4WU2A 3M4UA 2H04A 2WGPA 4GWFA 3V0IA 2H4VA 1OEMX 4QAHA 5K23A 4HJQA 3B7OA 2CM2A 2QCJA 2DXPA 1P15A 3EB1A 3O4TA 2ZMMA 2CMAA 3RZ2A 4JNBA 1QZ0A 2HXPA 1YPTA 2HY3A 2M3VA 2GP0A 3D1HA 4GRYA 1YTWA 1XBOA 5KA8A 4IKCA 2JJDA 5LXQB 2F70A 2CMBA 2HNPA 1YTSA 5K25A 4JMJA 2B4SA 3QCIA 5J8RA 5KA4A 5K24A 4BJOA 4NWFA 5K9WA 2Q05A 2A3KA 3I80A 1ONZA 2J16B 2Q47A 4KYRA 1BZHA 3LJ8A 1YGUA 1M3GA 2G6ZA 4D3QA 3O5XA 1G7FA 3V0JA 2A8BA 3RO1A 1XXVA 4QAPA 4ZI4A 5BZXA 5IBSA 1NO6A 1PH0A 2I42A 1PTTA 4OHIA 5KA1A 2CFVA 3PS5A 1Q6JA 2Y96A 4YAAA 1U26A 4H34A 3SR9A 3AWEA 2QEPA 1C84A 3QKQA 3ZMQA 2VEXA 3V0EA 5HDEA 2CNGA 3S3FA 2BIJA 2F71A 2ESBA 1R6HA 3GXHA 5GTJA 1SUGA 2HC2A 5I6VA 3QCCA 1XRIA 1GFYA 3QKPA 4R0SA 1NZ7A 2F6TA 5KA9A 1T4JA 1OEOX 1G1GA 2P4DA 1OEVA 1XXPA 1ONYA 2I6PA 2MBCA 4OHLA 1V3AA 3D44A 3S4OA 2B3OA 2VEVA 3F41A 3QCEA 3SMEA 1KAVA 2F6FA 5KABA 2I5XA 4ICZA 3MOWA 1PTUA 3N0AA 4HJPA 3RGOA 3BM8A 1YGRA 3S3KA 1LARA 3A5KA 1PA9A 1Q6TA 2OOQA 4PYHA 1PTYA 3QCKA 2B07A 1ZZWA 4B04A 2VEYA 2I4GA 4QUMA 4DGXA 2YDUA 4WU3A 5K22A 1PTVA 2H02A 3U96A 3AWFA 4NWGA 2C46A 2FJNA 2BGDA 4GE6A 1ZC0A 4WTYA 1NNYA 1OESA 4QUNA 2QCTA 5M43A 3AWGA 2E0TA 1FQ1A 2I75A 3F9BA 1L8GA 5KA0A 4D3PA 1YFOA 4RH9A 3S3HA 3ZM1A 3O4SA 3F99A 2CNHA 1EENA 1Q6NA 2QDCA 1WAXA 3I36A 5KA3A 2PBNA 2CM7A 2I6MA 3V0HA 5MMZB 4NNDA 1G4US 3F81A 4RI5A 1OHDA 4MBBA 5KADA 3RGQA 1FPZA 1YWFA 3A5JA 1OHCA 4KYQA 1Q6PA 1ECVA 1GWZA 2AZRA 4TVVA 2B4PA 3ZV2A 2RF6A 5EHPA 2C7SA 1OETA 4KI9A 2QDMA 2CNEA 3QCNA 2F6VA 4NYHA 2I6IA 2QBPA 5BUGA 3QCGA 3F9AA 3EAXA 2BGEA 2PSZA 1YN9A 4Y2EA 2I3UA 1QXKA 4OHDA 1T49A 2H03A 2J16A 3QCLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCB A;  2NT7 A;  3BLT A;  1ZCK A;  2CMC A;  1PYN A;  3EMU A;  2VEW A;  2CNI A;  3MMJ A;  1T48 A;  4RHG A;  3OLR A;  4GRZ A;  4WOH A;  2QBR A;  2B49 A;  4H1O A;  2R0B A;  1C83 A;  1WCH A;  2B4U A;  2NZ6 A;  4Y14 A;  1AAX A;  2PA5 A;  1PXH A;  2FH7 A;  4RH5 A;  2I1Y A;  1OEU A;  2PI7 A;  1KAK A;  1RPM A;  2CM8 A;  2ZN7 A;  4HRF A;  3ZM3 A;  2QBS A;  2CM3 A;  3QCH A;  4S0G A;  3D1O A;  4RI4 A;  4GS0 A;  1U25 A;  4GE2 A;  3V0D A;  2HC1 A;  3ZM0 A;  1I57 A;  2NTA A;  3ZM2 A;  4RKK A;  1NL9 A;  5KA2 A;  1PA1 A;  2I4E A;  2PT0 A;  2SHP A;  1LYV A;  1L8K A;  4JMK A;  1C87 A;  3S3E A;  1C88 A;  4RDD A;  1G1H A;  2GWO A;  4J51 A;  1FPR A;  3V0F A;  5EHR A;  4D3R A;  4OHE A;  3V0G A;  4BPC A;  1G1F A;  1WRM A;  3GXG A;  3EU0 A;  2OZ5 A;  4Z6B A;  2IMG A;  4I8N A;  4YR8 B;  5BZZ A;  4JBC A;  4GFU A;  3S4E A;  1BZJ A;  2F6Z A;  3QCF A;  1VHR A;  1XM2 A;  4ZN5 A;  2P6X A;  1X24 A;  2I6O A;  2BV5 A;  3ZMP A;  2OUD A;  1A5Y A;  3OMH A;  5KA7 A;  5KAA A;  2NV5 A;  4QBE A;  4R0T A;  4ERC A;  1RXD A;  1OHE A;  2F6Y A;  2I4H A;  3QCJ A;  3CM3 A;  2QDP A;  3NME A;  1EEO A;  4PVG A;  3CWE A;  1NWE A;  1I9T A;  2H4G A;  3EZZ A;  2OC3 A;  1C85 A;  2CNF A;  2PQ5 A;  1YZ4 A;  2AHS A;  3H2X A;  3BRH A;  1Q6S A;  2HVL A;  1G7G A;  1YTN A;  2NLK A;  2HCM A;  2J17 A;  1Q1M A;  1MKP A;  2FJM A;  2BZL A;  1LQF A;  4GE5 A;  2H4K A;  3O4U A;  3D42 A;  1Q6M A;  2CJZ A;  2I3R A;  3QCM A;  1J4X A;  2HNQ A;  3I7Z A;  5K9V A;  2GJT A;  3O3L A;  4OHH A;  4AZ1 A;  5KAC A;  5AWX A;  2F6W A;  1BZC A;  4GFV A;  1NWL A;  1D5R A;  1I9S A;  1ZCL A;  4QBW A;  1G4W R;  3D9C A;  4R30 A;  1JLN A;  2B4O A;  2G59 A;  2HB1 A;  4NX8 A;  2Y2F A;  2VEU A;  3BLU A;  2F46 A;  2QBQ A;  5BX1 A;  3QCD A;  3MOZ A;  4ZRT A;  1C86 A;  1JF7 A;  2NT2 A;  5IBM A;  2I6J A;  4DGP A;  1U24 A;  3D1Q A;  4WU2 A;  3M4U A;  2H04 A;  2WGP A;  4GWF A;  3V0I A;  2H4V A;  1OEM X;  4QAH A;  5K23 A;  4HJQ A;  3B7O A;  2CM2 A;  2QCJ A;  2DXP A;  1P15 A;  3EB1 A;  3O4T A;  2ZMM A;  2CMA A;  3RZ2 A;  4JNB A;  1QZ0 A;  2HXP A;  1YPT A;  2HY3 A;  2M3V A;  2GP0 A;  3D1H A;  4GRY A;  1YTW A;  1XBO A;  5KA8 A;  4IKC A;  2JJD A;  5LXQ B;  2F70 A;  2CMB A;  2HNP A;  1YTS A;  5K25 A;  4JMJ A;  2B4S A;  3QCI A;  5J8R A;  5KA4 A;  5K24 A;  4BJO A;  4NWF A;  5K9W A;  2Q05 A;  2A3K A;  3I80 A;  1ONZ A;  2J16 B;  2Q47 A;  4KYR A;  1BZH A;  3LJ8 A;  1YGU A;  1M3G A;  2G6Z A;  4D3Q A;  3O5X A;  1G7F A;  3V0J A;  2A8B A;  3RO1 A;  1XXV A;  4QAP A;  4ZI4 A;  5BZX A;  5IBS A;  1NO6 A;  1PH0 A;  2I42 A;  1PTT A;  4OHI A;  5KA1 A;  2CFV A;  3PS5 A;  1Q6J A;  2Y96 A;  4YAA A;  1U26 A;  4H34 A;  3SR9 A;  3AWE A;  2QEP A;  1C84 A;  3QKQ A;  3ZMQ A;  2VEX A;  3V0E A;  5HDE A;  2CNG A;  3S3F A;  2BIJ A;  2F71 A;  2ESB A;  1R6H A;  3GXH A;  5GTJ A;  1SUG A;  2HC2 A;  5I6V A;  3QCC A;  1XRI A;  1GFY A;  3QKP A;  4R0S A;  1NZ7 A;  2F6T A;  5KA9 A;  1T4J A;  1OEO X;  1G1G A;  2P4D A;  1OEV A;  1XXP A;  1ONY A;  2I6P A;  2MBC A;  4OHL A;  1V3A A;  3D44 A;  3S4O A;  2B3O A;  2VEV A;  3F41 A;  3QCE A;  3SME A;  1KAV A;  2F6F A;  5KAB A;  2I5X A;  4ICZ A;  3MOW A;  1PTU A;  3N0A A;  4HJP A;  3RGO A;  3BM8 A;  1YGR A;  3S3K A;  1LAR A;  3A5K A;  1PA9 A;  1Q6T A;  2OOQ A;  4PYH A;  1PTY A;  3QCK A;  2B07 A;  1ZZW A;  4B04 A;  2VEY A;  2I4G A;  4QUM A;  4DGX A;  2YDU A;  4WU3 A;  5K22 A;  1PTV A;  2H02 A;  3U96 A;  3AWF A;  4NWG A;  2C46 A;  2FJN A;  2BGD A;  4GE6 A;  1ZC0 A;  4WTY A;  1NNY A;  1OES A;  4QUN A;  2QCT A;  5M43 A;  3AWG A;  2E0T A;  1FQ1 A;  2I75 A;  3F9B A;  1L8G A;  5KA0 A;  4D3P A;  1YFO A;  4RH9 A;  3S3H A;  3ZM1 A;  3O4S A;  3F99 A;  2CNH A;  1EEN A;  1Q6N A;  2QDC A;  1WAX A;  3I36 A;  5KA3 A;  2PBN A;  2CM7 A;  2I6M A;  3V0H A;  5MMZ B;  4NND A;  1G4U S;  3F81 A;  4RI5 A;  1OHD A;  4MBB A;  5KAD A;  3RGQ A;  1FPZ A;  1YWF A;  3A5J A;  1OHC A;  4KYQ A;  1Q6P A;  1ECV A;  1GWZ A;  2AZR A;  4TVV A;  2B4P A;  3ZV2 A;  2RF6 A;  5EHP A;  2C7S A;  1OET A;  4KI9 A;  2QDM A;  2CNE A;  3QCN A;  2F6V A;  4NYH A;  2I6I A;  2QBP A;  5BUG A;  3QCG A;  3F9A A;  3EAX A;  2BGE A;  2PSZ A;  1YN9 A;  4Y2E A;  2I3U A;  1QXK A;  4OHD A;  1T49 A;  2H03 A;  2J16 A;  3QCL A; 
#chains in the Genus database with same CATH topology
 3QCB A;  2NT7 A;  3BLT A;  1ZCK A;  2CMC A;  1PYN A;  3EMU A;  2VEW A;  2CNI A;  3MMJ A;  1T48 A;  4RHG A;  3OLR A;  4GRZ A;  4WOH A;  2QBR A;  2B49 A;  4H1O A;  2R0B A;  1C83 A;  1WCH A;  2B4U A;  2NZ6 A;  4Y14 A;  1AAX A;  2PA5 A;  1PXH A;  2FH7 A;  4RH5 A;  4ZIY A;  2I1Y A;  2X5O A;  1OEU A;  2PI7 A;  1KAK A;  2Y68 A;  1RPM A;  2CM8 A;  2ZN7 A;  4HRF A;  3ZM3 A;  2QBS A;  2CM3 A;  3QCH A;  1JBV A;  4S0G A;  3D1O A;  4RI4 A;  2XPC A;  4GS0 A;  1U25 A;  4GE2 A;  3V0D A;  2HC1 A;  3ZM0 A;  1I57 A;  2NTA A;  3ZM2 A;  4RKK A;  1NL9 A;  5KA2 A;  1PA1 A;  2I4E A;  2PT0 A;  1W78 A;  2SHP A;  1LYV A;  1L8K A;  4JMK A;  1C87 A;  3S3E A;  1C88 A;  4RDD A;  1G1H A;  2XJA A;  2GWO A;  4J51 A;  1FPR A;  3V0F A;  5EHR A;  2JFF A;  3HN7 A;  4D3R A;  4OHE A;  3V0G A;  4CVM A;  1GQQ A;  1G1F A;  4BPC A;  1WRM A;  2AM1 A;  3GXG A;  3EU0 A;  2OZ5 A;  4Z6B A;  2IMG A;  4I8N A;  4YR8 B;  5BZZ A;  4JBC A;  4GFU A;  3S4E A;  1BZJ A;  2VOS A;  2F6Z A;  4HV4 A;  2GCB A;  1VHR A;  1XM2 A;  3QCF A;  4ZN5 A;  2P6X A;  1X24 A;  2I6O A;  4QDI A;  2BV5 A;  3ZMP A;  2JFH A;  2OUD A;  2UAG A;  1A5Y A;  3OMH A;  5KA7 A;  5KAA A;  2NV5 A;  4QBE A;  4R0T A;  4ERC A;  1RXD A;  4BUC A;  1EEH A;  1OHE A;  2F6Y A;  2I4H A;  3QCJ A;  3CM3 A;  2QDP A;  3NME A;  1EEO A;  4PVG A;  1E8C A;  3CWE A;  1NWE A;  1I9T A;  2H4G A;  3EZZ A;  2OC3 A;  1C85 A;  2CNF A;  2PQ5 A;  1YZ4 A;  2VTD A;  4UAG A;  2GC5 A;  2AHS A;  3H2X A;  3BRH A;  1Q6S A;  2HVL A;  1G7G A;  1YTN A;  2NLK A;  2HCM A;  1GG4 A;  2J17 A;  2VOR A;  1Q1M A;  4C13 A;  1MKP A;  2FJM A;  2BZL A;  1LQF A;  4GE5 A;  2H4K A;  3O4U A;  3D42 A;  1Q6M A;  2CJZ A;  2I3R A;  3QCM A;  1J4X A;  1E0D A;  2HNQ A;  3I7Z A;  5K9V A;  2GJT A;  3O3L A;  4OHH A;  4AZ1 A;  5KAC A;  5AWX A;  2F6W A;  1BZC A;  4GFV A;  2WTZ A;  1NWL A;  1D5R A;  1I9S A;  1ZCL A;  4QBW A;  1G4W R;  3D9C A;  4R30 A;  1JLN A;  2B4O A;  2G59 A;  2HB1 A;  4NX8 A;  2Y2F A;  2VEU A;  3BLU A;  2F46 A;  2QBQ A;  5BX1 A;  3QCD A;  3MOZ A;  4ZRT A;  1C86 A;  1JF7 A;  2NT2 A;  5IBM A;  2I6J A;  4DGP A;  1U24 A;  3D1Q A;  4WU2 A;  3M4U A;  2H04 A;  2WGP A;  4GWF A;  1UAG A;  3V0I A;  2H4V A;  1OEM X;  4QAH A;  5K23 A;  4HJQ A;  3B7O A;  2CM2 A;  2QCJ A;  2DXP A;  1P15 A;  3EB1 A;  3O4T A;  1J6U A;  2ZMM A;  2CMA A;  3RZ2 A;  4CVK A;  4JNB A;  1QZ0 A;  2HXP A;  1YPT A;  2HY3 A;  2M3V A;  2GP0 A;  3D1H A;  4GRY A;  2Y66 A;  1YTW A;  1XBO A;  5KA8 A;  4IKC A;  2JJD A;  5LXQ B;  2F70 A;  2CMB A;  5A5F A;  2HNP A;  1JBW A;  1YTS A;  5K25 A;  2GCA A;  4JMJ A;  2B4S A;  3QCI A;  5J8R A;  5KA4 A;  5K24 A;  4BJO A;  4NWF A;  5K9W A;  2Q05 A;  2A3K A;  3I80 A;  1ONZ A;  2J16 B;  2Q47 A;  4KYR A;  1BZH A;  3LJ8 A;  1YGU A;  2Y1O A;  1M3G A;  2G6Z A;  4D3Q A;  3O5X A;  1G7F A;  3V0J A;  2UUP A;  2A8B A;  3RO1 A;  1XXV A;  4QAP A;  4ZI4 A;  3NRS A;  5BZX A;  5IBS A;  1NO6 A;  1PH0 A;  2I42 A;  1PTT A;  4OHI A;  5KA1 A;  2CFV A;  3PS5 A;  1Q6J A;  2AM2 A;  2Y96 A;  4YAA A;  3UAG A;  1U26 A;  4H34 A;  3SR9 A;  1W7K A;  2VTE A;  3AWE A;  2QEP A;  1C84 A;  3QKQ A;  3ZMQ A;  2VEX A;  3V0E A;  5HDE A;  2CNG A;  3S3F A;  2BIJ A;  2F71 A;  2ESB A;  4QF5 A;  1R6H A;  3GXH A;  5GTJ A;  1SUG A;  2HC2 A;  5I6V A;  3QCC A;  1XRI A;  1GFY A;  3QKP A;  4R0S A;  1NZ7 A;  1P31 A;  2F6T A;  3ZM5 A;  5KA9 A;  2Y67 A;  1T4J A;  1OEO X;  1G1G A;  2P4D A;  1OEV A;  1XXP A;  1ONY A;  2I6P A;  2MBC A;  4OHL A;  1V3A A;  3D44 A;  3S4O A;  2B3O A;  2VEV A;  3F41 A;  3QCE A;  3SME A;  1KAV A;  2F6F A;  5KAB A;  2I5X A;  3N2A A;  4ICZ A;  2UUO A;  3MOW A;  1PTU A;  3N0A A;  3LK7 A;  4HJP A;  3BM8 A;  1YGR A;  3RGO A;  3S3K A;  1LAR A;  3A5K A;  1PA9 A;  1Q6T A;  2OOQ A;  4PYH A;  2WJP A;  3MVN A;  1PTY A;  3QCK A;  2B07 A;  1ZZW A;  4B04 A;  3ZM6 A;  2VEY A;  2I4G A;  4C12 A;  1FGS A;  4BUB A;  2GC6 A;  4QUM A;  4DGX A;  2YDU A;  4WU3 A;  5K22 A;  1PTV A;  2H02 A;  5A5E A;  3U96 A;  3AWF A;  4NWG A;  2C46 A;  2FJN A;  2BGD A;  4CVL A;  4GE6 A;  1ZC0 A;  4WTY A;  1NNY A;  1OES A;  3PYZ A;  4QUN A;  2QCT A;  5M43 A;  3AWG A;  2E0T A;  1FQ1 A;  2I75 A;  3F9B A;  1L8G A;  5KA0 A;  4D3P A;  1YFO A;  3QCZ A;  4RH9 A;  3S3H A;  3ZM1 A;  3O4S A;  3F99 A;  2CNH A;  1EEN A;  1Q6N A;  2QDC A;  1WAX A;  3I36 A;  5KA3 A;  2PBN A;  2CM7 A;  2I6M A;  3V0H A;  5MMZ B;  4NND A;  1G4U S;  3F81 A;  1O5Z A;  4RI5 A;  1OHD A;  4MBB A;  5KAD A;  3RGQ A;  1FPZ A;  1YWF A;  3A5J A;  1OHC A;  4KYQ A;  1P3D A;  1Q6P A;  1ECV A;  1GWZ A;  2AZR A;  4TVV A;  2B4P A;  3ZV2 A;  2RF6 A;  5EHP A;  2C7S A;  1OET A;  4KI9 A;  3ZL8 A;  1GQY A;  2QDM A;  2CNE A;  3QCN A;  2F6V A;  4NYH A;  2I6I A;  2QBP A;  5BUG A;  2F00 A;  3QCG A;  3F9A A;  3EAX A;  2BGE A;  2JFG A;  2PSZ A;  1YN9 A;  4Y2E A;  2I3U A;  1QXK A;  4OHD A;  1T49 A;  2H03 A;  2J16 A;  3QCL A; 
#chains in the Genus database with same CATH homology
 3QCB A;  2NT7 A;  3BLT A;  1ZCK A;  2CMC A;  1PYN A;  3EMU A;  2VEW A;  2CNI A;  3MMJ A;  1T48 A;  4RHG A;  3OLR A;  4GRZ A;  4WOH A;  2QBR A;  2B49 A;  4H1O A;  2R0B A;  1C83 A;  1WCH A;  2B4U A;  2NZ6 A;  4Y14 A;  1AAX A;  2PA5 A;  1PXH A;  2FH7 A;  4RH5 A;  2I1Y A;  1OEU A;  2PI7 A;  1KAK A;  1RPM A;  2CM8 A;  2ZN7 A;  4HRF A;  3ZM3 A;  2QBS A;  2CM3 A;  3QCH A;  4S0G A;  3D1O A;  4RI4 A;  4GS0 A;  1U25 A;  4GE2 A;  3V0D A;  2HC1 A;  3ZM0 A;  1I57 A;  2NTA A;  3ZM2 A;  4RKK A;  1NL9 A;  5KA2 A;  1PA1 A;  2I4E A;  2PT0 A;  2SHP A;  1LYV A;  1L8K A;  4JMK A;  1C87 A;  3S3E A;  1C88 A;  4RDD A;  1G1H A;  2GWO A;  4J51 A;  1FPR A;  3V0F A;  5EHR A;  4D3R A;  4OHE A;  3V0G A;  4BPC A;  1G1F A;  1WRM A;  3GXG A;  3EU0 A;  2OZ5 A;  4Z6B A;  2IMG A;  4I8N A;  4YR8 B;  5BZZ A;  4JBC A;  4GFU A;  3S4E A;  1BZJ A;  2F6Z A;  3QCF A;  1VHR A;  1XM2 A;  4ZN5 A;  2P6X A;  1X24 A;  2I6O A;  2BV5 A;  3ZMP A;  2OUD A;  1A5Y A;  3OMH A;  5KA7 A;  5KAA A;  2NV5 A;  4QBE A;  4R0T A;  4ERC A;  1RXD A;  1OHE A;  2F6Y A;  2I4H A;  3QCJ A;  3CM3 A;  2QDP A;  3NME A;  1EEO A;  4PVG A;  3CWE A;  1NWE A;  1I9T A;  2H4G A;  3EZZ A;  2OC3 A;  1C85 A;  2CNF A;  2PQ5 A;  1YZ4 A;  2AHS A;  3H2X A;  3BRH A;  1Q6S A;  2HVL A;  1G7G A;  1YTN A;  2NLK A;  2HCM A;  2J17 A;  1Q1M A;  1MKP A;  2FJM A;  2BZL A;  1LQF A;  4GE5 A;  2H4K A;  3O4U A;  3D42 A;  1Q6M A;  2CJZ A;  2I3R A;  3QCM A;  1J4X A;  2HNQ A;  3I7Z A;  5K9V A;  2GJT A;  3O3L A;  4OHH A;  4AZ1 A;  5KAC A;  5AWX A;  2F6W A;  1BZC A;  4GFV A;  1NWL A;  1D5R A;  1I9S A;  1ZCL A;  4QBW A;  1G4W R;  3D9C A;  4R30 A;  1JLN A;  2B4O A;  2G59 A;  2HB1 A;  4NX8 A;  2Y2F A;  2VEU A;  3BLU A;  2F46 A;  2QBQ A;  5BX1 A;  3QCD A;  3MOZ A;  4ZRT A;  1C86 A;  1JF7 A;  2NT2 A;  5IBM A;  2I6J A;  4DGP A;  1U24 A;  3D1Q A;  4WU2 A;  3M4U A;  2H04 A;  2WGP A;  4GWF A;  3V0I A;  2H4V A;  1OEM X;  4QAH A;  5K23 A;  4HJQ A;  3B7O A;  2CM2 A;  2QCJ A;  2DXP A;  1P15 A;  3EB1 A;  3O4T A;  2ZMM A;  2CMA A;  3RZ2 A;  4JNB A;  1QZ0 A;  2HXP A;  1YPT A;  2HY3 A;  2M3V A;  2GP0 A;  3D1H A;  4GRY A;  1YTW A;  1XBO A;  5KA8 A;  4IKC A;  2JJD A;  5LXQ B;  2F70 A;  2CMB A;  2HNP A;  1YTS A;  5K25 A;  4JMJ A;  2B4S A;  3QCI A;  5J8R A;  5KA4 A;  5K24 A;  4BJO A;  4NWF A;  5K9W A;  2Q05 A;  2A3K A;  3I80 A;  1ONZ A;  2J16 B;  2Q47 A;  4KYR A;  1BZH A;  3LJ8 A;  1YGU A;  1M3G A;  2G6Z A;  4D3Q A;  3O5X A;  1G7F A;  3V0J A;  2A8B A;  3RO1 A;  1XXV A;  4QAP A;  4ZI4 A;  5BZX A;  5IBS A;  1NO6 A;  1PH0 A;  2I42 A;  1PTT A;  4OHI A;  5KA1 A;  2CFV A;  3PS5 A;  1Q6J A;  2Y96 A;  4YAA A;  1U26 A;  4H34 A;  3SR9 A;  3AWE A;  2QEP A;  1C84 A;  3QKQ A;  3ZMQ A;  2VEX A;  3V0E A;  5HDE A;  2CNG A;  3S3F A;  2BIJ A;  2F71 A;  2ESB A;  1R6H A;  3GXH A;  5GTJ A;  1SUG A;  2HC2 A;  5I6V A;  3QCC A;  1XRI A;  1GFY A;  3QKP A;  4R0S A;  1NZ7 A;  2F6T A;  5KA9 A;  1T4J A;  1OEO X;  1G1G A;  2P4D A;  1OEV A;  1XXP A;  1ONY A;  2I6P A;  2MBC A;  4OHL A;  1V3A A;  3D44 A;  3S4O A;  2B3O A;  2VEV A;  3F41 A;  3QCE A;  3SME A;  1KAV A;  2F6F A;  5KAB A;  2I5X A;  4ICZ A;  3MOW A;  1PTU A;  3N0A A;  4HJP A;  3RGO A;  3BM8 A;  1YGR A;  3S3K A;  1LAR A;  3A5K A;  1PA9 A;  1Q6T A;  2OOQ A;  4PYH A;  1PTY A;  3QCK A;  2B07 A;  1ZZW A;  4B04 A;  2VEY A;  2I4G A;  4QUM A;  4DGX A;  2YDU A;  4WU3 A;  5K22 A;  1PTV A;  2H02 A;  3U96 A;  3AWF A;  4NWG A;  2C46 A;  2FJN A;  2BGD A;  4GE6 A;  1ZC0 A;  4WTY A;  1NNY A;  1OES A;  4QUN A;  2QCT A;  5M43 A;  3AWG A;  2E0T A;  1FQ1 A;  2I75 A;  3F9B A;  1L8G A;  5KA0 A;  4D3P A;  1YFO A;  4RH9 A;  3S3H A;  3ZM1 A;  3O4S A;  3F99 A;  2CNH A;  1EEN A;  1Q6N A;  2QDC A;  1WAX A;  3I36 A;  5KA3 A;  2PBN A;  2CM7 A;  2I6M A;  3V0H A;  5MMZ B;  4NND A;  1G4U S;  3F81 A;  4RI5 A;  1OHD A;  4MBB A;  5KAD A;  3RGQ A;  1FPZ A;  1YWF A;  3A5J A;  1OHC A;  4KYQ A;  1Q6P A;  1ECV A;  1GWZ A;  2AZR A;  4TVV A;  2B4P A;  3ZV2 A;  2RF6 A;  5EHP A;  2C7S A;  1OET A;  4KI9 A;  2QDM A;  2CNE A;  3QCN A;  2F6V A;  4NYH A;  2I6I A;  2QBP A;  5BUG A;  3QCG A;  3F9A A;  3EAX A;  2BGE A;  2PSZ A;  1YN9 A;  4Y2E A;  2I3U A;  1QXK A;  4OHD A;  1T49 A;  2H03 A;  2J16 A;  3QCL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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