2CM7A

Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
296
structure length
296
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 104
structure length 296
sequence length 296
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cm7A00
3QCCA 2NLKA 1PTTA 1OEUA 4OHIA 3I36A 4GRYA 2CM3A 2F71A 2F6ZA 2QCTA 5KABA 2OZ5A 3O4SA 2DXPA 4J51A 1R6HA 2J16B 3PS5A 2CFVA 3MOZA 2Q47A 1G4US 1MKPA 1Q6PA 1XXVA 4QAPA 4NNDA 1PH0A 4HJPA 2Y2FA 2I6MA 2PBNA 2I75A 4HRFA 2I4EA 4KYQA 4MBBA 2F6VA 4GE6A 4ZRTA 5KA3A 3N0AA 2NTAA 5M43A 2RF6A 3QCIA 3AWEA 3ZV2A 1NL9A 2AHSA 2SHPA 1ECVA 3F81A 4RH5A 1NNYA 1QZ0A 2E0TA 5MMZB 3BLTA 3EAXA 4IKCA 4QUNA 1C86A 1G7GA 5HDEA 4DGXA 2FJMA 3SMEA 1ZCKA 3V0FA 3ZMPA 2G59A 1XBOA 4QBEA 2BGEA 4HJQA 3ZM2A 1C84A 2CM7A 2CNEA 5KA9A 3CWEA 3S3EA 3OMHA 2H4KA 1OHCA 2CM2A 1T48A 1OHDA 3QCJA 4RHGA 4R0SA 4AZ1A 1G1HA 3D9CA 4S0GA 2B4OA 1D5RA 3CM3A 3S4EA 5KA0A 5BZZA 1M3GA 2VEWA 2B4PA 4WTYA 1P15A 1PTYA 3EU0A 3I7ZA 3D42A 5KAAA 3V0EA 2I6JA 3A5KA 4JMKA 4ZI4A 4I8NA 2NZ6A 3D44A 3QCKA 3S3FA 4ICZA 5KA4A 4GWFA 2R0BA 3GXHA 4B04A 5KA7A 2A8BA 3V0JA 1V3AA 2J16A 1PTUA 1YZ4A 2HC2A 1A5YA 1NWLA 4DGPA 4H1OA 3SR9A 1PA9A 2OOQA 3D1OA 1BZHA 1PTVA 3LJ8A 4JBCA 3O3LA 2I4GA 3QCHA 3MMJA 2F6FA 2CNHA 1WCHA 4NX8A 4PYHA 1Q6SA 2I5XA 5IBMA 2M3VA 2HNPA 1Q6TA 1FPRA 1YTSA 2VEXA 4RI4A 2HCMA 1OEOX 1PYNA 1C87A 4R0TA 4R30A 1BZJA 3EB1A 2NT7A 3EMUA 4RH9A 2CMBA 1KAVA 2HNQA 5IBSA 1OEMX 2QBRA 3U96A 1QXKA 1BZCA 1YWFA 1I9TA 3D1QA 4Y14A 1YTWA 3RO1A 2NT2A 4GFVA 3QCNA 1LQFA 2MBCA 2PSZA 1KAKA 2HY3A 1NO6A 3BLUA 4WU3A 3QCEA 4ERCA 1ZCLA 1C88A 2VEUA 5I6VA 2H4GA 2QDMA 5J8RA 3ZM3A 2CMCA 1U24A 4D3QA 2GP0A 3QCLA 4GRZA 1PA1A 5KACA 5BZXA 1G7FA 2ESBA 1G1GA 1YFOA 3D1HA 2I4HA 5K23A 2NV5A 4GE5A 2B4UA 3S3KA 4ZN5A 2VEYA 1U26A 2CNFA 3V0GA 5BX1A 2CM8A 1ONZA 2ZMMA 2BZLA 1WAXA 4WOHA 5K9WA 2QCJA 4RI5A 3ZMQA 1XM2A 3NMEA 2BIJA 1WRMA 4RDDA 3BM8A 2H02A 3ZM1A 2I6PA 1Q6MA 2HC1A 2IMGA 1NZ7A 4H34A 4WU2A 2I1YA 2I3UA 1L8GA 2PI7A 2HXPA 5LXQB 3ZM0A 1Q1MA 2PA5A 1JLNA 1OHEA 2HVLA 1EEOA 4D3PA 2B3OA 1J4XA 4GFUA 4TVVA 1LARA 1L8KA 4YAAA 4OHLA 1VHRA 4OHDA 1G1FA 2B49A 1XXPA 1LYVA 1PXHA 3F9BA 3V0IA 2H4VA 4YR8B 1EENA 3QCGA 3QCFA 2FJNA 3F99A 3S4OA 1I57A 1G4WR 4NYHA 2YDUA 5EHPA 1YGRA 2H04A 3V0HA 1Q6JA 1C85A 3V0DA 2A3KA 2QDPA 3H2XA 1NWEA 4QUMA 2CMAA 3F9AA 4OHEA 2JJDA 2AZRA 5EHRA 1YGUA 2HB1A 3QKQA 1Q6NA 3QKPA 2OC3A 4KYRA 2Q05A 3S3HA 2H03A 5GTJA 2QEPA 3RGQA 3O4TA 5KA1A 5K25A 2CNIA 2C7SA 2WGPA 2CNGA 5KADA 3O5XA 1RPMA 5K24A 1C83A 3I80A 1OETA 2F46A 3RGOA 3OLRA 3O4UA 4QAHA 1OESA 2QBQA 4GE2A 4BJOA 1ONYA 2P4DA 3AWFA 1SUGA 4JNBA 5K22A 3F41A 2QBPA 2B07A 3A5JA 2VEVA 1ZC0A 5AWXA 1RXDA 2I6IA 4JMJA 4NWFA 4NWGA 4D3RA 2F6YA 1GFYA 2G6ZA 3MOWA 1AAXA 1XRIA 5BUGA 1T4JA 5K9VA 1U25A 2I42A 4BPCA 1GWZA 2BGDA 2GJTA 3RZ2A 3AWGA 3M4UA 2CJZA 5KA2A 1YTNA 2J17A 2C46A 2Y96A 2PT0A 4KI9A 1YN9A 4RKKA 1T49A 4OHHA 4GS0A 2PQ5A 1YPTA 2GWOA 2QDCA 2QBSA 3BRHA 4PVGA 2F6WA 1JF7A 5KA8A 2I6OA 3QCDA 2P6XA 1I9SA 3QCMA 4QBWA 1OEVA 2F70A 3QCBA 1ZZWA 2B4SA 3B7OA 3GXGA 1X24A 2F6TA 4Z6BA 1FPZA 4Y2EA 1FQ1A 2I3RA 3EZZA 2BV5A 2ZN7A 2OUDA 2FH7A
chains in the Genus database with same CATH superfamily
3QCCA 2NLKA 1PTTA 1OEUA 5A5EA 4OHIA 3I36A 4GRYA 2CM3A 2Y66A 2F71A 2F6ZA 2QCTA 5KABA 2OZ5A 3O4SA 4CVLA 2X5OA 2DXPA 2GC5A 4J51A 1R6HA 2J16B 3PS5A 2CFVA 3MOZA 2Q47A 1G4US 1MKPA 1Q6PA 1XXVA 4QAPA 4NNDA 1P31A 1PH0A 4HJPA 2Y2FA 2I6MA 2PBNA 2F00A 3PYZA 2I75A 2GCAA 4HRFA 2I4EA 4KYQA 4MBBA 2F6VA 4GE6A 4ZRTA 5KA3A 3N0AA 2NTAA 5M43A 2RF6A 3QCIA 3AWEA 3ZV2A 1NL9A 2AHSA 2SHPA 1FGSA 1ECVA 3F81A 4RH5A 1GG4A 1NNYA 1QZ0A 2E0TA 1O5ZA 5MMZB 3NRSA 3BLTA 3EAXA 4IKCA 4UAGA 4QUNA 1C86A 1G7GA 2XJAA 5HDEA 4DGXA 2FJMA 3SMEA 1ZCKA 4BUCA 3V0FA 3ZMPA 2G59A 1XBOA 4QBEA 2BGEA 2VTDA 4HJQA 3ZM2A 1C84A 2CM7A 2CNEA 5KA9A 3CWEA 3S3EA 3OMHA 2H4KA 1OHCA 2CM2A 1T48A 1OHDA 3QCJA 4RHGA 4R0SA 4AZ1A 1G1HA 3D9CA 4S0GA 2B4OA 2UAGA 1D5RA 3CM3A 4CVMA 2GC6A 3S4EA 5KA0A 5BZZA 2VOSA 1M3GA 5A5FA 2VEWA 2B4PA 4WTYA 1W7KA 1P15A 1PTYA 3EU0A 3I7ZA 3D42A 5KAAA 3V0EA 2I6JA 3A5KA 4JMKA 4ZI4A 2UUPA 4I8NA 2NZ6A 2GCBA 3D44A 3QCKA 3S3FA 2JFGA 4ICZA 5KA4A 4C13A 4GWFA 2R0BA 3GXHA 4B04A 5KA7A 1GQYA 2A8BA 3V0JA 1V3AA 2J16A 1PTUA 1YZ4A 2HC2A 1A5YA 1NWLA 4DGPA 4H1OA 3SR9A 2VTEA 1PA9A 2OOQA 3D1OA 1BZHA 1PTVA 3ZM5A 3LJ8A 4JBCA 2WTZA 3HN7A 3O3LA 2I4GA 3QCHA 3MMJA 2F6FA 2CNHA 1J6UA 1WCHA 4NX8A 4PYHA 4QF5A 1Q6SA 2I5XA 5IBMA 2M3VA 2HNPA 1Q6TA 1FPRA 3LK7A 1YTSA 3ZM6A 3ZL8A 2VEXA 1JBVA 4RI4A 2HCMA 1OEOX 1PYNA 1C87A 4R0TA 4R30A 1BZJA 3EB1A 3N2AA 2NT7A 3EMUA 4RH9A 2CMBA 1KAVA 2HNQA 5IBSA 1OEMX 2QBRA 3U96A 1QXKA 1BZCA 1YWFA 1I9TA 2UUOA 3D1QA 4Y14A 1YTWA 3RO1A 2NT2A 4GFVA 3QCNA 1LQFA 2MBCA 2PSZA 1KAKA 2HY3A 1NO6A 3BLUA 4WU3A 3QCEA 4ERCA 1ZCLA 2WJPA 1C88A 2VEUA 5I6VA 2H4GA 2QDMA 5J8RA 3ZM3A 2CMCA 1U24A 4D3QA 2GP0A 3QCLA 4GRZA 1PA1A 5KACA 1P3DA 5BZXA 1G7FA 2ESBA 1G1GA 1YFOA 3D1HA 2I4HA 5K23A 2NV5A 4GE5A 2B4UA 3S3KA 4ZN5A 2VEYA 2VORA 1U26A 2CNFA 3V0GA 5BX1A 2CM8A 1ONZA 1E8CA 2ZMMA 2BZLA 1WAXA 4WOHA 5K9WA 2QCJA 4RI5A 3ZMQA 1XM2A 3NMEA 2BIJA 3UAGA 1WRMA 4RDDA 3BM8A 2H02A 3ZM1A 2Y1OA 2I6PA 1Q6MA 2HC1A 2IMGA 1NZ7A 4H34A 4WU2A 2I1YA 2I3UA 1L8GA 2PI7A 2AM1A 2HXPA 5LXQB 3ZM0A 4C12A 1E0DA 4HV4A 1Q1MA 2PA5A 1JLNA 1OHEA 2HVLA 1EEOA 4D3PA 2B3OA 2Y67A 1J4XA 1GQQA 4GFUA 4TVVA 1LARA 1L8KA 4YAAA 4ZIYA 4OHLA 1VHRA 4OHDA 1G1FA 2B49A 1XXPA 1LYVA 1PXHA 3F9BA 3V0IA 2H4VA 4YR8B 1EENA 3QCGA 3QCFA 2FJNA 3F99A 3S4OA 1I57A 1G4WR 4NYHA 3MVNA 2YDUA 5EHPA 1YGRA 2H04A 3V0HA 1Q6JA 1C85A 3V0DA 2A3KA 2AM2A 2QDPA 3H2XA 1NWEA 4QUMA 2CMAA 3F9AA 4OHEA 2JJDA 1UAGA 2AZRA 5EHRA 4BUBA 1YGUA 2HB1A 3QKQA 1W78A 1Q6NA 3QKPA 2OC3A 4KYRA 2Q05A 3S3HA 2JFFA 2H03A 5GTJA 2QEPA 3RGQA 3O4TA 5KA1A 5K25A 2CNIA 2C7SA 2WGPA 2CNGA 5KADA 3O5XA 1RPMA 5K24A 1C83A 3I80A 1OETA 2F46A 3RGOA 3OLRA 3O4UA 4QAHA 1OESA 2QBQA 4GE2A 4BJOA 1ONYA 2P4DA 3AWFA 1SUGA 4JNBA 5K22A 3F41A 2QBPA 2B07A 3A5JA 2VEVA 1ZC0A 5AWXA 2Y68A 1RXDA 2I6IA 4JMJA 4NWFA 2XPCA 4NWGA 4D3RA 2F6YA 1GFYA 2G6ZA 3MOWA 1AAXA 1XRIA 5BUGA 1T4JA 5K9VA 1U25A 2I42A 1EEHA 4BPCA 1GWZA 2BGDA 2GJTA 3RZ2A 3AWGA 3M4UA 2CJZA 5KA2A 1YTNA 2J17A 2C46A 2Y96A 2PT0A 4KI9A 4CVKA 1YN9A 4RKKA 1T49A 4OHHA 4GS0A 2PQ5A 1YPTA 2GWOA 2QDCA 2QBSA 3BRHA 2JFHA 4PVGA 2F6WA 1JF7A 5KA8A 2I6OA 3QCDA 1JBWA 2P6XA 1I9SA 3QCMA 3QCZA 1OEVA 2F70A 4QBWA 3QCBA 1ZZWA 2B4SA 3B7OA 3GXGA 1X24A 2F6TA 4QDIA 4Z6BA 1FPZA 4Y2EA 1FQ1A 2I3RA 3EZZA 2BV5A 2ZN7A 2OUDA 2FH7A
chains in the Genus database with same CATH topology
3QCCA 2NLKA 1PTTA 1OEUA 4OHIA 3I36A 4GRYA 2CM3A 2F71A 2F6ZA 2QCTA 5KABA 2OZ5A 3O4SA 2DXPA 4J51A 1R6HA 2J16B 3PS5A 2CFVA 3MOZA 2Q47A 1G4US 1MKPA 1Q6PA 1XXVA 4QAPA 4NNDA 1PH0A 4HJPA 2Y2FA 2I6MA 2PBNA 2I75A 4HRFA 2I4EA 4KYQA 4MBBA 2F6VA 4GE6A 4ZRTA 5KA3A 3N0AA 2NTAA 5M43A 2RF6A 3QCIA 3AWEA 3ZV2A 1NL9A 2AHSA 2SHPA 1ECVA 3F81A 4RH5A 1NNYA 1QZ0A 2E0TA 5MMZB 3BLTA 3EAXA 4IKCA 4QUNA 1C86A 1G7GA 5HDEA 4DGXA 2FJMA 3SMEA 1ZCKA 3V0FA 3ZMPA 2G59A 1XBOA 4QBEA 2BGEA 4HJQA 3ZM2A 1C84A 2CM7A 2CNEA 5KA9A 3CWEA 3S3EA 3OMHA 2H4KA 1OHCA 2CM2A 1T48A 1OHDA 3QCJA 4RHGA 4R0SA 4AZ1A 1G1HA 3D9CA 4S0GA 2B4OA 1D5RA 3CM3A 3S4EA 5KA0A 5BZZA 1M3GA 2VEWA 2B4PA 4WTYA 1P15A 1PTYA 3EU0A 3I7ZA 3D42A 5KAAA 3V0EA 2I6JA 3A5KA 4JMKA 4ZI4A 4I8NA 2NZ6A 3D44A 3QCKA 3S3FA 4ICZA 5KA4A 4GWFA 2R0BA 3GXHA 4B04A 5KA7A 2A8BA 3V0JA 1V3AA 2J16A 1PTUA 1YZ4A 2HC2A 1A5YA 1NWLA 4DGPA 4H1OA 3SR9A 1PA9A 2OOQA 3D1OA 1BZHA 1PTVA 3LJ8A 4JBCA 3O3LA 2I4GA 3QCHA 3MMJA 2F6FA 2CNHA 1WCHA 4NX8A 4PYHA 1Q6SA 2I5XA 5IBMA 2M3VA 2HNPA 1Q6TA 1FPRA 1YTSA 2VEXA 4RI4A 2HCMA 1OEOX 1PYNA 1C87A 4R0TA 4R30A 1BZJA 3EB1A 2NT7A 3EMUA 4RH9A 2CMBA 1KAVA 2HNQA 5IBSA 1OEMX 2QBRA 3U96A 1QXKA 1BZCA 1YWFA 1I9TA 3D1QA 4Y14A 1YTWA 3RO1A 2NT2A 4GFVA 3QCNA 1LQFA 2MBCA 2PSZA 1KAKA 2HY3A 1NO6A 3BLUA 4WU3A 3QCEA 4ERCA 1ZCLA 1C88A 2VEUA 5I6VA 2H4GA 2QDMA 5J8RA 3ZM3A 2CMCA 1U24A 4D3QA 2GP0A 3QCLA 4GRZA 1PA1A 5KACA 5BZXA 1G7FA 2ESBA 1G1GA 1YFOA 3D1HA 2I4HA 5K23A 2NV5A 4GE5A 2B4UA 3S3KA 4ZN5A 2VEYA 1U26A 2CNFA 3V0GA 5BX1A 2CM8A 1ONZA 2ZMMA 2BZLA 1WAXA 4WOHA 5K9WA 2QCJA 4RI5A 3ZMQA 1XM2A 3NMEA 2BIJA 1WRMA 4RDDA 3BM8A 2H02A 3ZM1A 2I6PA 1Q6MA 2HC1A 2IMGA 1NZ7A 4H34A 4WU2A 2I1YA 2I3UA 1L8GA 2PI7A 2HXPA 5LXQB 3ZM0A 1Q1MA 2PA5A 1JLNA 1OHEA 2HVLA 1EEOA 4D3PA 2B3OA 1J4XA 4GFUA 4TVVA 1LARA 1L8KA 4YAAA 4OHLA 1VHRA 4OHDA 1G1FA 2B49A 1XXPA 1LYVA 1PXHA 3F9BA 3V0IA 2H4VA 4YR8B 1EENA 3QCGA 3QCFA 2FJNA 3F99A 3S4OA 1I57A 1G4WR 4NYHA 2YDUA 5EHPA 1YGRA 2H04A 3V0HA 1Q6JA 1C85A 3V0DA 2A3KA 2QDPA 3H2XA 1NWEA 4QUMA 2CMAA 3F9AA 4OHEA 2JJDA 2AZRA 5EHRA 1YGUA 2HB1A 3QKQA 1Q6NA 3QKPA 2OC3A 4KYRA 2Q05A 3S3HA 2H03A 5GTJA 2QEPA 3RGQA 3O4TA 5KA1A 5K25A 2CNIA 2C7SA 2WGPA 2CNGA 5KADA 3O5XA 1RPMA 5K24A 1C83A 3I80A 1OETA 2F46A 3RGOA 3OLRA 3O4UA 4QAHA 1OESA 2QBQA 4GE2A 4BJOA 1ONYA 2P4DA 3AWFA 1SUGA 4JNBA 5K22A 3F41A 2QBPA 2B07A 3A5JA 2VEVA 1ZC0A 5AWXA 1RXDA 2I6IA 4JMJA 4NWFA 4NWGA 4D3RA 2F6YA 1GFYA 2G6ZA 3MOWA 1AAXA 1XRIA 5BUGA 1T4JA 5K9VA 1U25A 2I42A 4BPCA 1GWZA 2BGDA 2GJTA 3RZ2A 3AWGA 3M4UA 2CJZA 5KA2A 1YTNA 2J17A 2C46A 2Y96A 2PT0A 4KI9A 1YN9A 4RKKA 1T49A 4OHHA 4GS0A 2PQ5A 1YPTA 2GWOA 2QDCA 2QBSA 3BRHA 4PVGA 2F6WA 1JF7A 5KA8A 2I6OA 3QCDA 2P6XA 1I9SA 3QCMA 4QBWA 1OEVA 2F70A 3QCBA 1ZZWA 2B4SA 3B7OA 3GXGA 1X24A 2F6TA 4Z6BA 1FPZA 4Y2EA 1FQ1A 2I3RA 3EZZA 2BV5A 2ZN7A 2OUDA 2FH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCC A;  2NLK A;  1PTT A;  1OEU A;  4OHI A;  3I36 A;  4GRY A;  2CM3 A;  2F71 A;  2F6Z A;  2QCT A;  5KAB A;  2OZ5 A;  3O4S A;  2DXP A;  4J51 A;  1R6H A;  2J16 B;  3PS5 A;  2CFV A;  3MOZ A;  2Q47 A;  1G4U S;  1MKP A;  1Q6P A;  1XXV A;  4QAP A;  4NND A;  1PH0 A;  4HJP A;  2Y2F A;  2I6M A;  2PBN A;  2I75 A;  4HRF A;  2I4E A;  4KYQ A;  4MBB A;  2F6V A;  4GE6 A;  4ZRT A;  5KA3 A;  3N0A A;  2NTA A;  5M43 A;  2RF6 A;  3QCI A;  3AWE A;  3ZV2 A;  1NL9 A;  2AHS A;  2SHP A;  1ECV A;  3F81 A;  4RH5 A;  1NNY A;  1QZ0 A;  2E0T A;  5MMZ B;  3BLT A;  3EAX A;  4IKC A;  4QUN A;  1C86 A;  1G7G A;  5HDE A;  4DGX A;  2FJM A;  3SME A;  1ZCK A;  3V0F A;  3ZMP A;  2G59 A;  1XBO A;  4QBE A;  2BGE A;  4HJQ A;  3ZM2 A;  1C84 A;  2CM7 A;  2CNE A;  5KA9 A;  3CWE A;  3S3E A;  3OMH A;  2H4K A;  1OHC A;  2CM2 A;  1T48 A;  1OHD A;  3QCJ A;  4RHG A;  4R0S A;  4AZ1 A;  1G1H A;  3D9C A;  4S0G A;  2B4O A;  1D5R A;  3CM3 A;  3S4E A;  5KA0 A;  5BZZ A;  1M3G A;  2VEW A;  2B4P A;  4WTY A;  1P15 A;  1PTY A;  3EU0 A;  3I7Z A;  3D42 A;  5KAA A;  3V0E A;  2I6J A;  3A5K A;  4JMK A;  4ZI4 A;  4I8N A;  2NZ6 A;  3D44 A;  3QCK A;  3S3F A;  4ICZ A;  5KA4 A;  4GWF A;  2R0B A;  3GXH A;  4B04 A;  5KA7 A;  2A8B A;  3V0J A;  1V3A A;  2J16 A;  1PTU A;  1YZ4 A;  2HC2 A;  1A5Y A;  1NWL A;  4DGP A;  4H1O A;  3SR9 A;  1PA9 A;  2OOQ A;  3D1O A;  1BZH A;  1PTV A;  3LJ8 A;  4JBC A;  3O3L A;  2I4G A;  3QCH A;  3MMJ A;  2F6F A;  2CNH A;  1WCH A;  4NX8 A;  4PYH A;  1Q6S A;  2I5X A;  5IBM A;  2M3V A;  2HNP A;  1Q6T A;  1FPR A;  1YTS A;  2VEX A;  4RI4 A;  2HCM A;  1OEO X;  1PYN A;  1C87 A;  4R0T A;  4R30 A;  1BZJ A;  3EB1 A;  2NT7 A;  3EMU A;  4RH9 A;  2CMB A;  1KAV A;  2HNQ A;  5IBS A;  1OEM X;  2QBR A;  3U96 A;  1QXK A;  1BZC A;  1YWF A;  1I9T A;  3D1Q A;  4Y14 A;  1YTW A;  3RO1 A;  2NT2 A;  4GFV A;  3QCN A;  1LQF A;  2MBC A;  2PSZ A;  1KAK A;  2HY3 A;  1NO6 A;  3BLU A;  4WU3 A;  3QCE A;  4ERC A;  1ZCL A;  1C88 A;  2VEU A;  5I6V A;  2H4G A;  2QDM A;  5J8R A;  3ZM3 A;  2CMC A;  1U24 A;  4D3Q A;  2GP0 A;  3QCL A;  4GRZ A;  1PA1 A;  5KAC A;  5BZX A;  1G7F A;  2ESB A;  1G1G A;  1YFO A;  3D1H A;  2I4H A;  5K23 A;  2NV5 A;  4GE5 A;  2B4U A;  3S3K A;  4ZN5 A;  2VEY A;  1U26 A;  2CNF A;  3V0G A;  5BX1 A;  2CM8 A;  1ONZ A;  2ZMM A;  2BZL A;  1WAX A;  4WOH A;  5K9W A;  2QCJ A;  4RI5 A;  3ZMQ A;  1XM2 A;  3NME A;  2BIJ A;  1WRM A;  4RDD A;  3BM8 A;  2H02 A;  3ZM1 A;  2I6P A;  1Q6M A;  2HC1 A;  2IMG A;  1NZ7 A;  4H34 A;  4WU2 A;  2I1Y A;  2I3U A;  1L8G A;  2PI7 A;  2HXP A;  5LXQ B;  3ZM0 A;  1Q1M A;  2PA5 A;  1JLN A;  1OHE A;  2HVL A;  1EEO A;  4D3P A;  2B3O A;  1J4X A;  4GFU A;  4TVV A;  1LAR A;  1L8K A;  4YAA A;  4OHL A;  1VHR A;  4OHD A;  1G1F A;  2B49 A;  1XXP A;  1LYV A;  1PXH A;  3F9B A;  3V0I A;  2H4V A;  4YR8 B;  1EEN A;  3QCG A;  3QCF A;  2FJN A;  3F99 A;  3S4O A;  1I57 A;  1G4W R;  4NYH A;  2YDU A;  5EHP A;  1YGR A;  2H04 A;  3V0H A;  1Q6J A;  1C85 A;  3V0D A;  2A3K A;  2QDP A;  3H2X A;  1NWE A;  4QUM A;  2CMA A;  3F9A A;  4OHE A;  2JJD A;  2AZR A;  5EHR A;  1YGU A;  2HB1 A;  3QKQ A;  1Q6N A;  3QKP A;  2OC3 A;  4KYR A;  2Q05 A;  3S3H A;  2H03 A;  5GTJ A;  2QEP A;  3RGQ A;  3O4T A;  5KA1 A;  5K25 A;  2CNI A;  2C7S A;  2WGP A;  2CNG A;  5KAD A;  3O5X A;  1RPM A;  5K24 A;  1C83 A;  3I80 A;  1OET A;  2F46 A;  3RGO A;  3OLR A;  3O4U A;  4QAH A;  1OES A;  2QBQ A;  4GE2 A;  4BJO A;  1ONY A;  2P4D A;  3AWF A;  1SUG A;  4JNB A;  5K22 A;  3F41 A;  2QBP A;  2B07 A;  3A5J A;  2VEV A;  1ZC0 A;  5AWX A;  1RXD A;  2I6I A;  4JMJ A;  4NWF A;  4NWG A;  4D3R A;  2F6Y A;  1GFY A;  2G6Z A;  3MOW A;  1AAX A;  1XRI A;  5BUG A;  1T4J A;  5K9V A;  1U25 A;  2I42 A;  4BPC A;  1GWZ A;  2BGD A;  2GJT A;  3RZ2 A;  3AWG A;  3M4U A;  2CJZ A;  5KA2 A;  1YTN A;  2J17 A;  2C46 A;  2Y96 A;  2PT0 A;  4KI9 A;  1YN9 A;  4RKK A;  1T49 A;  4OHH A;  4GS0 A;  2PQ5 A;  1YPT A;  2GWO A;  2QDC A;  2QBS A;  3BRH A;  4PVG A;  2F6W A;  1JF7 A;  5KA8 A;  2I6O A;  3QCD A;  2P6X A;  1I9S A;  3QCM A;  4QBW A;  1OEV A;  2F70 A;  3QCB A;  1ZZW A;  2B4S A;  3B7O A;  3GXG A;  1X24 A;  2F6T A;  4Z6B A;  1FPZ A;  4Y2E A;  1FQ1 A;  2I3R A;  3EZZ A;  2BV5 A;  2ZN7 A;  2OUD A;  2FH7 A; 
#chains in the Genus database with same CATH topology
 3QCC A;  2NLK A;  1PTT A;  1OEU A;  5A5E A;  4OHI A;  3I36 A;  4GRY A;  2CM3 A;  2Y66 A;  2F71 A;  2F6Z A;  2QCT A;  5KAB A;  2OZ5 A;  3O4S A;  4CVL A;  2X5O A;  2DXP A;  2GC5 A;  4J51 A;  1R6H A;  2J16 B;  3PS5 A;  2CFV A;  3MOZ A;  2Q47 A;  1G4U S;  1MKP A;  1Q6P A;  1XXV A;  4QAP A;  4NND A;  1P31 A;  1PH0 A;  4HJP A;  2Y2F A;  2I6M A;  2PBN A;  2F00 A;  3PYZ A;  2I75 A;  2GCA A;  4HRF A;  2I4E A;  4KYQ A;  4MBB A;  2F6V A;  4GE6 A;  4ZRT A;  5KA3 A;  3N0A A;  2NTA A;  5M43 A;  2RF6 A;  3QCI A;  3AWE A;  3ZV2 A;  1NL9 A;  2AHS A;  2SHP A;  1FGS A;  1ECV A;  3F81 A;  4RH5 A;  1GG4 A;  1NNY A;  1QZ0 A;  2E0T A;  1O5Z A;  5MMZ B;  3NRS A;  3BLT A;  3EAX A;  4IKC A;  4UAG A;  4QUN A;  1C86 A;  1G7G A;  2XJA A;  5HDE A;  4DGX A;  2FJM A;  3SME A;  1ZCK A;  4BUC A;  3V0F A;  3ZMP A;  2G59 A;  1XBO A;  4QBE A;  2BGE A;  2VTD A;  4HJQ A;  3ZM2 A;  1C84 A;  2CM7 A;  2CNE A;  5KA9 A;  3CWE A;  3S3E A;  3OMH A;  2H4K A;  1OHC A;  2CM2 A;  1T48 A;  1OHD A;  3QCJ A;  4RHG A;  4R0S A;  4AZ1 A;  1G1H A;  3D9C A;  4S0G A;  2B4O A;  2UAG A;  1D5R A;  3CM3 A;  4CVM A;  2GC6 A;  3S4E A;  5KA0 A;  5BZZ A;  2VOS A;  1M3G A;  5A5F A;  2VEW A;  2B4P A;  4WTY A;  1W7K A;  1P15 A;  1PTY A;  3EU0 A;  3I7Z A;  3D42 A;  5KAA A;  3V0E A;  2I6J A;  3A5K A;  4JMK A;  4ZI4 A;  2UUP A;  4I8N A;  2NZ6 A;  2GCB A;  3D44 A;  3QCK A;  3S3F A;  2JFG A;  4ICZ A;  5KA4 A;  4C13 A;  4GWF A;  2R0B A;  3GXH A;  4B04 A;  5KA7 A;  1GQY A;  2A8B A;  3V0J A;  1V3A A;  2J16 A;  1PTU A;  1YZ4 A;  2HC2 A;  1A5Y A;  1NWL A;  4DGP A;  4H1O A;  3SR9 A;  2VTE A;  1PA9 A;  2OOQ A;  3D1O A;  1BZH A;  1PTV A;  3ZM5 A;  3LJ8 A;  4JBC A;  2WTZ A;  3HN7 A;  3O3L A;  2I4G A;  3QCH A;  3MMJ A;  2F6F A;  2CNH A;  1J6U A;  1WCH A;  4NX8 A;  4PYH A;  4QF5 A;  1Q6S A;  2I5X A;  5IBM A;  2M3V A;  2HNP A;  1Q6T A;  1FPR A;  3LK7 A;  1YTS A;  3ZM6 A;  3ZL8 A;  2VEX A;  1JBV A;  4RI4 A;  2HCM A;  1OEO X;  1PYN A;  1C87 A;  4R0T A;  4R30 A;  1BZJ A;  3EB1 A;  3N2A A;  2NT7 A;  3EMU A;  4RH9 A;  2CMB A;  1KAV A;  2HNQ A;  5IBS A;  1OEM X;  2QBR A;  3U96 A;  1QXK A;  1BZC A;  1YWF A;  1I9T A;  2UUO A;  3D1Q A;  4Y14 A;  1YTW A;  3RO1 A;  2NT2 A;  4GFV A;  3QCN A;  1LQF A;  2MBC A;  2PSZ A;  1KAK A;  2HY3 A;  1NO6 A;  3BLU A;  4WU3 A;  3QCE A;  4ERC A;  1ZCL A;  2WJP A;  1C88 A;  2VEU A;  5I6V A;  2H4G A;  2QDM A;  5J8R A;  3ZM3 A;  2CMC A;  1U24 A;  4D3Q A;  2GP0 A;  3QCL A;  4GRZ A;  1PA1 A;  5KAC A;  1P3D A;  5BZX A;  1G7F A;  2ESB A;  1G1G A;  1YFO A;  3D1H A;  2I4H A;  5K23 A;  2NV5 A;  4GE5 A;  2B4U A;  3S3K A;  4ZN5 A;  2VEY A;  2VOR A;  1U26 A;  2CNF A;  3V0G A;  5BX1 A;  2CM8 A;  1ONZ A;  1E8C A;  2ZMM A;  2BZL A;  1WAX A;  4WOH A;  5K9W A;  2QCJ A;  4RI5 A;  3ZMQ A;  1XM2 A;  3NME A;  2BIJ A;  3UAG A;  1WRM A;  4RDD A;  3BM8 A;  2H02 A;  3ZM1 A;  2Y1O A;  2I6P A;  1Q6M A;  2HC1 A;  2IMG A;  1NZ7 A;  4H34 A;  4WU2 A;  2I1Y A;  2I3U A;  1L8G A;  2PI7 A;  2AM1 A;  2HXP A;  5LXQ B;  3ZM0 A;  4C12 A;  1E0D A;  4HV4 A;  1Q1M A;  2PA5 A;  1JLN A;  1OHE A;  2HVL A;  1EEO A;  4D3P A;  2B3O A;  2Y67 A;  1J4X A;  1GQQ A;  4GFU A;  4TVV A;  1LAR A;  1L8K A;  4YAA A;  4ZIY A;  4OHL A;  1VHR A;  4OHD A;  1G1F A;  2B49 A;  1XXP A;  1LYV A;  1PXH A;  3F9B A;  3V0I A;  2H4V A;  4YR8 B;  1EEN A;  3QCG A;  3QCF A;  2FJN A;  3F99 A;  3S4O A;  1I57 A;  1G4W R;  4NYH A;  3MVN A;  2YDU A;  5EHP A;  1YGR A;  2H04 A;  3V0H A;  1Q6J A;  1C85 A;  3V0D A;  2A3K A;  2AM2 A;  2QDP A;  3H2X A;  1NWE A;  4QUM A;  2CMA A;  3F9A A;  4OHE A;  2JJD A;  1UAG A;  2AZR A;  5EHR A;  4BUB A;  1YGU A;  2HB1 A;  3QKQ A;  1W78 A;  1Q6N A;  3QKP A;  2OC3 A;  4KYR A;  2Q05 A;  3S3H A;  2JFF A;  2H03 A;  5GTJ A;  2QEP A;  3RGQ A;  3O4T A;  5KA1 A;  5K25 A;  2CNI A;  2C7S A;  2WGP A;  2CNG A;  5KAD A;  3O5X A;  1RPM A;  5K24 A;  1C83 A;  3I80 A;  1OET A;  2F46 A;  3RGO A;  3OLR A;  3O4U A;  4QAH A;  1OES A;  2QBQ A;  4GE2 A;  4BJO A;  1ONY A;  2P4D A;  3AWF A;  1SUG A;  4JNB A;  5K22 A;  3F41 A;  2QBP A;  2B07 A;  3A5J A;  2VEV A;  1ZC0 A;  5AWX A;  2Y68 A;  1RXD A;  2I6I A;  4JMJ A;  4NWF A;  2XPC A;  4NWG A;  4D3R A;  2F6Y A;  1GFY A;  2G6Z A;  3MOW A;  1AAX A;  1XRI A;  5BUG A;  1T4J A;  5K9V A;  1U25 A;  2I42 A;  1EEH A;  4BPC A;  1GWZ A;  2BGD A;  2GJT A;  3RZ2 A;  3AWG A;  3M4U A;  2CJZ A;  5KA2 A;  1YTN A;  2J17 A;  2C46 A;  2Y96 A;  2PT0 A;  4KI9 A;  4CVK A;  1YN9 A;  4RKK A;  1T49 A;  4OHH A;  4GS0 A;  2PQ5 A;  1YPT A;  2GWO A;  2QDC A;  2QBS A;  3BRH A;  2JFH A;  4PVG A;  2F6W A;  1JF7 A;  5KA8 A;  2I6O A;  3QCD A;  1JBW A;  2P6X A;  1I9S A;  3QCM A;  3QCZ A;  1OEV A;  2F70 A;  4QBW A;  3QCB A;  1ZZW A;  2B4S A;  3B7O A;  3GXG A;  1X24 A;  2F6T A;  4QDI A;  4Z6B A;  1FPZ A;  4Y2E A;  1FQ1 A;  2I3R A;  3EZZ A;  2BV5 A;  2ZN7 A;  2OUD A;  2FH7 A; 
#chains in the Genus database with same CATH homology
 3QCC A;  2NLK A;  1PTT A;  1OEU A;  4OHI A;  3I36 A;  4GRY A;  2CM3 A;  2F71 A;  2F6Z A;  2QCT A;  5KAB A;  2OZ5 A;  3O4S A;  2DXP A;  4J51 A;  1R6H A;  2J16 B;  3PS5 A;  2CFV A;  3MOZ A;  2Q47 A;  1G4U S;  1MKP A;  1Q6P A;  1XXV A;  4QAP A;  4NND A;  1PH0 A;  4HJP A;  2Y2F A;  2I6M A;  2PBN A;  2I75 A;  4HRF A;  2I4E A;  4KYQ A;  4MBB A;  2F6V A;  4GE6 A;  4ZRT A;  5KA3 A;  3N0A A;  2NTA A;  5M43 A;  2RF6 A;  3QCI A;  3AWE A;  3ZV2 A;  1NL9 A;  2AHS A;  2SHP A;  1ECV A;  3F81 A;  4RH5 A;  1NNY A;  1QZ0 A;  2E0T A;  5MMZ B;  3BLT A;  3EAX A;  4IKC A;  4QUN A;  1C86 A;  1G7G A;  5HDE A;  4DGX A;  2FJM A;  3SME A;  1ZCK A;  3V0F A;  3ZMP A;  2G59 A;  1XBO A;  4QBE A;  2BGE A;  4HJQ A;  3ZM2 A;  1C84 A;  2CM7 A;  2CNE A;  5KA9 A;  3CWE A;  3S3E A;  3OMH A;  2H4K A;  1OHC A;  2CM2 A;  1T48 A;  1OHD A;  3QCJ A;  4RHG A;  4R0S A;  4AZ1 A;  1G1H A;  3D9C A;  4S0G A;  2B4O A;  1D5R A;  3CM3 A;  3S4E A;  5KA0 A;  5BZZ A;  1M3G A;  2VEW A;  2B4P A;  4WTY A;  1P15 A;  1PTY A;  3EU0 A;  3I7Z A;  3D42 A;  5KAA A;  3V0E A;  2I6J A;  3A5K A;  4JMK A;  4ZI4 A;  4I8N A;  2NZ6 A;  3D44 A;  3QCK A;  3S3F A;  4ICZ A;  5KA4 A;  4GWF A;  2R0B A;  3GXH A;  4B04 A;  5KA7 A;  2A8B A;  3V0J A;  1V3A A;  2J16 A;  1PTU A;  1YZ4 A;  2HC2 A;  1A5Y A;  1NWL A;  4DGP A;  4H1O A;  3SR9 A;  1PA9 A;  2OOQ A;  3D1O A;  1BZH A;  1PTV A;  3LJ8 A;  4JBC A;  3O3L A;  2I4G A;  3QCH A;  3MMJ A;  2F6F A;  2CNH A;  1WCH A;  4NX8 A;  4PYH A;  1Q6S A;  2I5X A;  5IBM A;  2M3V A;  2HNP A;  1Q6T A;  1FPR A;  1YTS A;  2VEX A;  4RI4 A;  2HCM A;  1OEO X;  1PYN A;  1C87 A;  4R0T A;  4R30 A;  1BZJ A;  3EB1 A;  2NT7 A;  3EMU A;  4RH9 A;  2CMB A;  1KAV A;  2HNQ A;  5IBS A;  1OEM X;  2QBR A;  3U96 A;  1QXK A;  1BZC A;  1YWF A;  1I9T A;  3D1Q A;  4Y14 A;  1YTW A;  3RO1 A;  2NT2 A;  4GFV A;  3QCN A;  1LQF A;  2MBC A;  2PSZ A;  1KAK A;  2HY3 A;  1NO6 A;  3BLU A;  4WU3 A;  3QCE A;  4ERC A;  1ZCL A;  1C88 A;  2VEU A;  5I6V A;  2H4G A;  2QDM A;  5J8R A;  3ZM3 A;  2CMC A;  1U24 A;  4D3Q A;  2GP0 A;  3QCL A;  4GRZ A;  1PA1 A;  5KAC A;  5BZX A;  1G7F A;  2ESB A;  1G1G A;  1YFO A;  3D1H A;  2I4H A;  5K23 A;  2NV5 A;  4GE5 A;  2B4U A;  3S3K A;  4ZN5 A;  2VEY A;  1U26 A;  2CNF A;  3V0G A;  5BX1 A;  2CM8 A;  1ONZ A;  2ZMM A;  2BZL A;  1WAX A;  4WOH A;  5K9W A;  2QCJ A;  4RI5 A;  3ZMQ A;  1XM2 A;  3NME A;  2BIJ A;  1WRM A;  4RDD A;  3BM8 A;  2H02 A;  3ZM1 A;  2I6P A;  1Q6M A;  2HC1 A;  2IMG A;  1NZ7 A;  4H34 A;  4WU2 A;  2I1Y A;  2I3U A;  1L8G A;  2PI7 A;  2HXP A;  5LXQ B;  3ZM0 A;  1Q1M A;  2PA5 A;  1JLN A;  1OHE A;  2HVL A;  1EEO A;  4D3P A;  2B3O A;  1J4X A;  4GFU A;  4TVV A;  1LAR A;  1L8K A;  4YAA A;  4OHL A;  1VHR A;  4OHD A;  1G1F A;  2B49 A;  1XXP A;  1LYV A;  1PXH A;  3F9B A;  3V0I A;  2H4V A;  4YR8 B;  1EEN A;  3QCG A;  3QCF A;  2FJN A;  3F99 A;  3S4O A;  1I57 A;  1G4W R;  4NYH A;  2YDU A;  5EHP A;  1YGR A;  2H04 A;  3V0H A;  1Q6J A;  1C85 A;  3V0D A;  2A3K A;  2QDP A;  3H2X A;  1NWE A;  4QUM A;  2CMA A;  3F9A A;  4OHE A;  2JJD A;  2AZR A;  5EHR A;  1YGU A;  2HB1 A;  3QKQ A;  1Q6N A;  3QKP A;  2OC3 A;  4KYR A;  2Q05 A;  3S3H A;  2H03 A;  5GTJ A;  2QEP A;  3RGQ A;  3O4T A;  5KA1 A;  5K25 A;  2CNI A;  2C7S A;  2WGP A;  2CNG A;  5KAD A;  3O5X A;  1RPM A;  5K24 A;  1C83 A;  3I80 A;  1OET A;  2F46 A;  3RGO A;  3OLR A;  3O4U A;  4QAH A;  1OES A;  2QBQ A;  4GE2 A;  4BJO A;  1ONY A;  2P4D A;  3AWF A;  1SUG A;  4JNB A;  5K22 A;  3F41 A;  2QBP A;  2B07 A;  3A5J A;  2VEV A;  1ZC0 A;  5AWX A;  1RXD A;  2I6I A;  4JMJ A;  4NWF A;  4NWG A;  4D3R A;  2F6Y A;  1GFY A;  2G6Z A;  3MOW A;  1AAX A;  1XRI A;  5BUG A;  1T4J A;  5K9V A;  1U25 A;  2I42 A;  4BPC A;  1GWZ A;  2BGD A;  2GJT A;  3RZ2 A;  3AWG A;  3M4U A;  2CJZ A;  5KA2 A;  1YTN A;  2J17 A;  2C46 A;  2Y96 A;  2PT0 A;  4KI9 A;  1YN9 A;  4RKK A;  1T49 A;  4OHH A;  4GS0 A;  2PQ5 A;  1YPT A;  2GWO A;  2QDC A;  2QBS A;  3BRH A;  4PVG A;  2F6W A;  1JF7 A;  5KA8 A;  2I6O A;  3QCD A;  2P6X A;  1I9S A;  3QCM A;  4QBW A;  1OEV A;  2F70 A;  3QCB A;  1ZZW A;  2B4S A;  3B7O A;  3GXG A;  1X24 A;  2F6T A;  4Z6B A;  1FPZ A;  4Y2E A;  1FQ1 A;  2I3R A;  3EZZ A;  2BV5 A;  2ZN7 A;  2OUD A;  2FH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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