2CMAA

Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
296
structure length
296
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 102
structure length 296
sequence length 296
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cmaA00
4RH5A 2F6VA 2H02A 1Q6MA 1QXKA 1Q6NA 3RGOA 2QBPA 1WCHA 1FQ1A 2F6TA 3D1OA 4GRYA 2C7SA 2B49A 3F41A 3EAXA 4NX8A 1G1GA 5KA8A 1BZCA 1BZHA 2BIJA 2CNHA 2QBRA 2AZRA 5BX1A 5K25A 2DXPA 4QBWA 4GRZA 5KABA 1MKPA 3F9BA 2AHSA 3BLUA 3EB1A 3LJ8A 4RHGA 1PYNA 2B3OA 1U26A 2F70A 1ZZWA 2I5XA 2I1YA 3QCJA 2QDCA 1PA9A 1RPMA 2GWOA 4NWGA 2J17A 1XBOA 1L8KA 2Y2FA 4ZRTA 3S3HA 1NO6A 1WRMA 3SR9A 3V0GA 3QCLA 2VEVA 3ZV2A 1P15A 2CJZA 2H03A 4Y14A 3N0AA 3M4UA 5K9VA 2HNPA 2I4GA 4RDDA 4D3RA 1C84A 5KA1A 1PTTA 3B7OA 4GS0A 1J4XA 5EHPA 2NLKA 4H1OA 1SUGA 1I57A 3V0HA 2HB1A 3CWEA 1PA1A 1M3GA 2ZMMA 2J16A 4TVVA 2QBSA 3GXHA 1T49A 2NT2A 2GP0A 2HXPA 3I7ZA 2ESBA 2HC2A 2VEYA 1L8GA 3QCDA 4PYHA 2OZ5A 4WU3A 5EHRA 2G6ZA 5LXQB 1OESA 1OHDA 3RGQA 4QAHA 5KA4A 2F71A 3I36A 2BZLA 1GWZA 5IBSA 1YGRA 2CMBA 1JLNA 4BJOA 4HJQA 1FPZA 2QCTA 1OHEA 3BM8A 2PT0A 4YAAA 3QKQA 3H2XA 2QBQA 1C88A 2CNGA 2PQ5A 2CNEA 1V3AA 5MMZB 5AWXA 3QKPA 5BZZA 1XXPA 3V0DA 2CM2A 1G7FA 1NNYA 3AWEA 2QDPA 2H4KA 1D5RA 5KA0A 3S4EA 3BRHA 2VEUA 1OHCA 2F6FA 3A5JA 1KAKA 3F9AA 4JNBA 1G7GA 3MOZA 4IKCA 4GE6A 3ZM1A 4RH9A 2J16B 2I6MA 2RF6A 5KADA 5KA7A 2CM3A 1R6HA 1FPRA 1U25A 4GFUA 2B07A 2IMGA 4ERCA 1ZCLA 2E0TA 3O4SA 2H4VA 3U96A 5GTJA 3NMEA 1OEVA 2B4OA 1G4US 2I6JA 2PSZA 5I6VA 5K24A 1EEOA 1A5YA 3D44A 2JJDA 2CM7A 4RI4A 2OUDA 3EZZA 2PA5A 1YGUA 5KA2A 2I4HA 1LQFA 1X24A 1XM2A 1ZCKA 4WTYA 3ZM0A 4DGPA 2OOQA 3D1HA 3S3EA 4ZN5A 2I75A 2CNFA 2HC1A 4H34A 2B4SA 3OMHA 2CMAA 2I6IA 3AWGA 2FH7A 3SMEA 4AZ1A 4OHIA 2R0BA 1YN9A 2WGPA 1YPTA 1Q6TA 4WOHA 4RI5A 1C86A 4J51A 2HCMA 2GJTA 3F81A 3EMUA 3ZMQA 3MMJA 4QUNA 4KYRA 4JBCA 3F99A 1G1HA 5KAAA 3O4TA 1ZC0A 1Q6PA 4JMKA 4Y2EA 1XRIA 2F46A 2NV5A 1OEUA 5BZXA 5K22A 1OEMX 1C85A 4R0TA 4OHLA 2F6YA 4YR8B 4R30A 3QCBA 1KAVA 1Q6JA 4QBEA 4ZI4A 3QCCA 3MOWA 2PBNA 3AWFA 1Q6SA 2QEPA 1ONZA 2PI7A 3CM3A 3D9CA 4KYQA 4KI9A 1YWFA 2B4UA 1GFYA 2H4GA 3QCFA 5M43A 2SHPA 1C87A 3BLTA 2I42A 2Q05A 4PVGA 4NWFA 2HNQA 4NYHA 1LARA 3I80A 3GXGA 4ICZA 3V0JA 5K23A 3D1QA 4QAPA 3PS5A 1G1FA 1AAXA 2QDMA 4BPCA 2I6OA 3ZM3A 3V0FA 2A3KA 1NL9A 4GFVA 1T4JA 3RZ2A 2MBCA 1NWEA 4GE2A 4S0GA 2F6WA 4I8NA 4OHEA 3S3KA 1OEOX 4RKKA 1ECVA 2HVLA 3V0EA 4B04A 4Z6BA 2I6PA 3O3LA 3EU0A 2CNIA 1YFOA 1EENA 1YTNA 1BZJA 2BV5A 3V0IA 1JF7A 2VEWA 4GE5A 3ZMPA 3S3FA 1YTSA 2QCJA 1RXDA 2Y96A 1PXHA 2Q47A 1Q1MA 2CMCA 2P6XA 2F6ZA 4MBBA 2I3UA 5HDEA 1XXVA 2M3VA 2B4PA 2CFVA 4HRFA 2G59A 4OHHA 1U24A 3QCHA 2A8BA 3D42A 2H04A 3QCNA 2ZN7A 2VEXA 2I3RA 1C83A 1T48A 4QUMA 1PTUA 4JMJA 5KA9A 3QCKA 2YDUA 1PH0A 2BGDA 4WU2A 1YZ4A 1I9TA 2BGEA 1QZ0A 1YTWA 3QCIA 1PTYA 1NZ7A 1G4WR 1LYVA 3QCMA 2HY3A 4OHDA 5J8RA 1ONYA 1VHRA 4R0SA 3ZM2A 2NZ6A 4D3PA 1I9SA 2I4EA 3O4UA 4NNDA 2NT7A 2CM8A 5BUGA 3OLRA 3QCEA 2FJMA 5K9WA 3RO1A 1OETA 5KACA 3A5KA 3O5XA 3S4OA 1WAXA 2FJNA 1PTVA 2C46A 2P4DA 4DGXA 5KA3A 4D3QA 4GWFA 3QCGA 5IBMA 2OC3A 2NTAA 1NWLA 4HJPA
chains in the Genus database with same CATH superfamily
1P31A 4RH5A 2F6VA 2WJPA 2H02A 1Q6MA 2Y67A 1QXKA 1Q6NA 3RGOA 2QBPA 1WCHA 1FQ1A 4C12A 2F6TA 2VORA 3D1OA 5A5EA 4GRYA 2C7SA 2B49A 3F41A 3EAXA 4NX8A 1G1GA 5KA8A 1BZCA 1BZHA 2BIJA 2Y1OA 2CNHA 2QBRA 2AZRA 5BX1A 5K25A 2DXPA 2XPCA 2GCBA 4QBWA 4GRZA 5KABA 2X5OA 1MKPA 3F9BA 2AHSA 3BLUA 3EB1A 3LJ8A 4RHGA 1PYNA 2B3OA 1U26A 2F70A 1ZZWA 2I5XA 2I1YA 3QCJA 2QDCA 1PA9A 1RPMA 2GWOA 4NWGA 1GQYA 2J17A 1XBOA 2UUOA 1L8KA 2Y2FA 4ZRTA 3S3HA 1NO6A 1WRMA 2VTDA 3SR9A 3V0GA 3HN7A 3QCLA 2VEVA 3ZV2A 1FGSA 1P15A 2CJZA 2H03A 4Y14A 3N0AA 3M4UA 5K9VA 2HNPA 3ZL8A 2I4GA 4RDDA 4D3RA 1C84A 5KA1A 1PTTA 3B7OA 4GS0A 1J4XA 5EHPA 2NLKA 4H1OA 1SUGA 1I57A 3V0HA 2HB1A 3CWEA 1PA1A 1M3GA 2ZMMA 2J16A 4TVVA 2QBSA 1UAGA 3GXHA 1T49A 2NT2A 2GP0A 2HXPA 3I7ZA 2ESBA 2HC2A 2VEYA 1L8GA 3QCDA 4PYHA 2OZ5A 4WU3A 1EEHA 2G6ZA 5EHRA 5LXQB 1OESA 1OHDA 3RGQA 4QAHA 5KA4A 2F71A 2XJAA 3I36A 2BZLA 1GWZA 5IBSA 1YGRA 2CMBA 1JLNA 4BJOA 4HJQA 1FPZA 2VTEA 2QCTA 1OHEA 3BM8A 2PT0A 4YAAA 3QKQA 3H2XA 4ZIYA 2QBQA 1C88A 2CNGA 2PQ5A 3UAGA 2CNEA 1V3AA 5MMZB 5AWXA 3QKPA 5BZZA 1XXPA 3V0DA 2CM2A 1G7FA 4C13A 1NNYA 3AWEA 2JFFA 2QDPA 2H4KA 1D5RA 5KA0A 3S4EA 3BRHA 2VEUA 1OHCA 2F6FA 3A5JA 1KAKA 3F9AA 4JNBA 1G7GA 3MOZA 4IKCA 4GE6A 3ZM1A 4RH9A 2J16B 2I6MA 2RF6A 5KADA 5KA7A 2CM3A 1R6HA 1FPRA 3N2AA 1U25A 4GFUA 2B07A 2IMGA 4ERCA 1GG4A 2GC5A 1ZCLA 2E0TA 3O4SA 2H4VA 3U96A 5GTJA 1E0DA 3NMEA 1OEVA 2B4OA 1G4US 2I6JA 2PSZA 5I6VA 5K24A 1EEOA 1A5YA 3D44A 2JJDA 2CM7A 4RI4A 2OUDA 3EZZA 2PA5A 1YGUA 5KA2A 2I4HA 1LQFA 4QDIA 1X24A 2JFHA 1W78A 1XM2A 1ZCKA 4WTYA 2Y66A 2WTZA 3ZM0A 4DGPA 2OOQA 3D1HA 3S3EA 4ZN5A 2I75A 2CNFA 2HC1A 4H34A 2B4SA 3OMHA 2CMAA 2I6IA 3AWGA 2FH7A 3SMEA 4CVKA 4AZ1A 4OHIA 2R0BA 1YN9A 2WGPA 1YPTA 1Q6TA 5A5FA 4WOHA 4RI5A 1C86A 4J51A 2HCMA 2GJTA 3F81A 3EMUA 3ZMQA 3MMJA 4QUNA 2VOSA 4KYRA 2UUPA 4BUCA 4JBCA 3F99A 1G1HA 5KAAA 3O4TA 1ZC0A 1Q6PA 2GC6A 4JMKA 4Y2EA 1XRIA 2F46A 3NRSA 2NV5A 1OEUA 5BZXA 5K22A 1OEMX 1C85A 4R0TA 4OHLA 2F6YA 2UAGA 4YR8B 4R30A 3QCBA 1KAVA 1Q6JA 4QBEA 4ZI4A 3QCCA 3MOWA 2PBNA 3AWFA 1P3DA 3PYZA 4BUBA 1Q6SA 2QEPA 1ONZA 1J6UA 2PI7A 3CM3A 3D9CA 2AM1A 4QF5A 1O5ZA 4KYQA 4KI9A 1YWFA 2B4UA 1GFYA 2H4GA 3QCFA 5M43A 2SHPA 1C87A 3BLTA 2I42A 2Q05A 4PVGA 4NWFA 2HNQA 4NYHA 1LARA 3I80A 3GXGA 4ICZA 4CVMA 3V0JA 5K23A 3D1QA 2AM2A 2GCAA 4QAPA 3PS5A 1G1FA 1AAXA 2QDMA 4BPCA 2I6OA 3MVNA 3ZM3A 3V0FA 2A3KA 1NL9A 4GFVA 1T4JA 3RZ2A 2MBCA 1NWEA 4GE2A 4S0GA 2F6WA 4I8NA 4OHEA 3S3KA 1OEOX 4RKKA 1ECVA 2HVLA 3V0EA 4HV4A 4B04A 4Z6BA 2I6PA 1JBWA 3O3LA 3EU0A 2CNIA 1YFOA 1EENA 1YTNA 1BZJA 2BV5A 3V0IA 1JF7A 2VEWA 4GE5A 3ZMPA 3S3FA 1YTSA 2QCJA 1RXDA 2Y96A 1PXHA 2Q47A 1Q1MA 2CMCA 2P6XA 2F6ZA 4MBBA 2I3UA 5HDEA 1XXVA 2M3VA 2B4PA 2CFVA 4HRFA 2G59A 4OHHA 4CVLA 2Y68A 1U24A 3QCHA 2A8BA 3D42A 2JFGA 2H04A 1JBVA 3QCNA 2ZN7A 2VEXA 2I3RA 1C83A 1T48A 4QUMA 1PTUA 4JMJA 3QCZA 5KA9A 1GQQA 3QCKA 2YDUA 1PH0A 2BGDA 4WU2A 1YZ4A 1I9TA 2BGEA 1QZ0A 1YTWA 3QCIA 1PTYA 1W7KA 1NZ7A 1G4WR 1LYVA 3QCMA 2HY3A 4OHDA 5J8RA 1ONYA 1VHRA 3ZM5A 4R0SA 3ZM2A 2NZ6A 4D3PA 1I9SA 2I4EA 3O4UA 3LK7A 2F00A 4NNDA 2NT7A 2CM8A 5BUGA 3OLRA 3ZM6A 4UAGA 3QCEA 2FJMA 5K9WA 3RO1A 1OETA 5KACA 3A5KA 3O5XA 1E8CA 3S4OA 2P4DA 1WAXA 2FJNA 1PTVA 2C46A 4DGXA 5KA3A 4D3QA 4GWFA 3QCGA 5IBMA 2OC3A 2NTAA 1NWLA 4HJPA
chains in the Genus database with same CATH topology
4RH5A 2F6VA 2H02A 1Q6MA 1QXKA 1Q6NA 3RGOA 2QBPA 1WCHA 1FQ1A 2F6TA 3D1OA 4GRYA 2C7SA 2B49A 3F41A 3EAXA 4NX8A 1G1GA 5KA8A 1BZCA 1BZHA 2BIJA 2CNHA 2QBRA 2AZRA 5BX1A 5K25A 2DXPA 4QBWA 4GRZA 5KABA 1MKPA 3F9BA 2AHSA 3BLUA 3EB1A 3LJ8A 4RHGA 1PYNA 2B3OA 1U26A 2F70A 1ZZWA 2I5XA 2I1YA 3QCJA 2QDCA 1PA9A 1RPMA 2GWOA 4NWGA 2J17A 1XBOA 1L8KA 2Y2FA 4ZRTA 3S3HA 1NO6A 1WRMA 3SR9A 3V0GA 3QCLA 2VEVA 3ZV2A 1P15A 2CJZA 2H03A 4Y14A 3N0AA 3M4UA 5K9VA 2HNPA 2I4GA 4RDDA 4D3RA 1C84A 5KA1A 1PTTA 3B7OA 4GS0A 1J4XA 5EHPA 2NLKA 4H1OA 1SUGA 1I57A 3V0HA 2HB1A 3CWEA 1PA1A 1M3GA 2ZMMA 2J16A 4TVVA 2QBSA 3GXHA 1T49A 2NT2A 2GP0A 2HXPA 3I7ZA 2ESBA 2HC2A 2VEYA 1L8GA 3QCDA 4PYHA 2OZ5A 4WU3A 5EHRA 2G6ZA 5LXQB 1OESA 1OHDA 3RGQA 4QAHA 5KA4A 2F71A 3I36A 2BZLA 1GWZA 5IBSA 1YGRA 2CMBA 1JLNA 4BJOA 4HJQA 1FPZA 2QCTA 1OHEA 3BM8A 2PT0A 4YAAA 3QKQA 3H2XA 2QBQA 1C88A 2CNGA 2PQ5A 2CNEA 1V3AA 5MMZB 5AWXA 3QKPA 5BZZA 1XXPA 3V0DA 2CM2A 1G7FA 1NNYA 3AWEA 2QDPA 2H4KA 1D5RA 5KA0A 3S4EA 3BRHA 2VEUA 1OHCA 2F6FA 3A5JA 1KAKA 3F9AA 4JNBA 1G7GA 3MOZA 4IKCA 4GE6A 3ZM1A 4RH9A 2J16B 2I6MA 2RF6A 5KADA 5KA7A 2CM3A 1R6HA 1FPRA 1U25A 4GFUA 2B07A 2IMGA 4ERCA 1ZCLA 2E0TA 3O4SA 2H4VA 3U96A 5GTJA 3NMEA 1OEVA 2B4OA 1G4US 2I6JA 2PSZA 5I6VA 5K24A 1EEOA 1A5YA 3D44A 2JJDA 2CM7A 4RI4A 2OUDA 3EZZA 2PA5A 1YGUA 5KA2A 2I4HA 1LQFA 1X24A 1XM2A 1ZCKA 4WTYA 3ZM0A 4DGPA 2OOQA 3D1HA 3S3EA 4ZN5A 2I75A 2CNFA 2HC1A 4H34A 2B4SA 3OMHA 2CMAA 2I6IA 3AWGA 2FH7A 3SMEA 4AZ1A 4OHIA 2R0BA 1YN9A 2WGPA 1YPTA 1Q6TA 4WOHA 4RI5A 1C86A 4J51A 2HCMA 2GJTA 3F81A 3EMUA 3ZMQA 3MMJA 4QUNA 4KYRA 4JBCA 3F99A 1G1HA 5KAAA 3O4TA 1ZC0A 1Q6PA 4JMKA 4Y2EA 1XRIA 2F46A 2NV5A 1OEUA 5BZXA 5K22A 1OEMX 1C85A 4R0TA 4OHLA 2F6YA 4YR8B 4R30A 3QCBA 1KAVA 1Q6JA 4QBEA 4ZI4A 3QCCA 3MOWA 2PBNA 3AWFA 1Q6SA 2QEPA 1ONZA 2PI7A 3CM3A 3D9CA 4KYQA 4KI9A 1YWFA 2B4UA 1GFYA 2H4GA 3QCFA 5M43A 2SHPA 1C87A 3BLTA 2I42A 2Q05A 4PVGA 4NWFA 2HNQA 4NYHA 1LARA 3I80A 3GXGA 4ICZA 3V0JA 5K23A 3D1QA 4QAPA 3PS5A 1G1FA 1AAXA 2QDMA 4BPCA 2I6OA 3ZM3A 3V0FA 2A3KA 1NL9A 4GFVA 1T4JA 3RZ2A 2MBCA 1NWEA 4GE2A 4S0GA 2F6WA 4I8NA 4OHEA 3S3KA 1OEOX 4RKKA 1ECVA 2HVLA 3V0EA 4B04A 4Z6BA 2I6PA 3O3LA 3EU0A 2CNIA 1YFOA 1EENA 1YTNA 1BZJA 2BV5A 3V0IA 1JF7A 2VEWA 4GE5A 3ZMPA 3S3FA 1YTSA 2QCJA 1RXDA 2Y96A 1PXHA 2Q47A 1Q1MA 2CMCA 2P6XA 2F6ZA 4MBBA 2I3UA 5HDEA 1XXVA 2M3VA 2B4PA 2CFVA 4HRFA 2G59A 4OHHA 1U24A 3QCHA 2A8BA 3D42A 2H04A 3QCNA 2ZN7A 2VEXA 2I3RA 1C83A 1T48A 4QUMA 1PTUA 4JMJA 5KA9A 3QCKA 2YDUA 1PH0A 2BGDA 4WU2A 1YZ4A 1I9TA 2BGEA 1QZ0A 1YTWA 3QCIA 1PTYA 1NZ7A 1G4WR 1LYVA 3QCMA 2HY3A 4OHDA 5J8RA 1ONYA 1VHRA 4R0SA 3ZM2A 2NZ6A 4D3PA 1I9SA 2I4EA 3O4UA 4NNDA 2NT7A 2CM8A 5BUGA 3OLRA 3QCEA 2FJMA 5K9WA 3RO1A 1OETA 5KACA 3A5KA 3O5XA 3S4OA 1WAXA 2FJNA 1PTVA 2C46A 2P4DA 4DGXA 5KA3A 4D3QA 4GWFA 3QCGA 5IBMA 2OC3A 2NTAA 1NWLA 4HJPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RH5 A;  2F6V A;  2H02 A;  1Q6M A;  1QXK A;  1Q6N A;  3RGO A;  2QBP A;  1WCH A;  1FQ1 A;  2F6T A;  3D1O A;  4GRY A;  2C7S A;  2B49 A;  3F41 A;  3EAX A;  4NX8 A;  1G1G A;  5KA8 A;  1BZC A;  1BZH A;  2BIJ A;  2CNH A;  2QBR A;  2AZR A;  5BX1 A;  5K25 A;  2DXP A;  4QBW A;  4GRZ A;  5KAB A;  1MKP A;  3F9B A;  2AHS A;  3BLU A;  3EB1 A;  3LJ8 A;  4RHG A;  1PYN A;  2B3O A;  1U26 A;  2F70 A;  1ZZW A;  2I5X A;  2I1Y A;  3QCJ A;  2QDC A;  1PA9 A;  1RPM A;  2GWO A;  4NWG A;  2J17 A;  1XBO A;  1L8K A;  2Y2F A;  4ZRT A;  3S3H A;  1NO6 A;  1WRM A;  3SR9 A;  3V0G A;  3QCL A;  2VEV A;  3ZV2 A;  1P15 A;  2CJZ A;  2H03 A;  4Y14 A;  3N0A A;  3M4U A;  5K9V A;  2HNP A;  2I4G A;  4RDD A;  4D3R A;  1C84 A;  5KA1 A;  1PTT A;  3B7O A;  4GS0 A;  1J4X A;  5EHP A;  2NLK A;  4H1O A;  1SUG A;  1I57 A;  3V0H A;  2HB1 A;  3CWE A;  1PA1 A;  1M3G A;  2ZMM A;  2J16 A;  4TVV A;  2QBS A;  3GXH A;  1T49 A;  2NT2 A;  2GP0 A;  2HXP A;  3I7Z A;  2ESB A;  2HC2 A;  2VEY A;  1L8G A;  3QCD A;  4PYH A;  2OZ5 A;  4WU3 A;  5EHR A;  2G6Z A;  5LXQ B;  1OES A;  1OHD A;  3RGQ A;  4QAH A;  5KA4 A;  2F71 A;  3I36 A;  2BZL A;  1GWZ A;  5IBS A;  1YGR A;  2CMB A;  1JLN A;  4BJO A;  4HJQ A;  1FPZ A;  2QCT A;  1OHE A;  3BM8 A;  2PT0 A;  4YAA A;  3QKQ A;  3H2X A;  2QBQ A;  1C88 A;  2CNG A;  2PQ5 A;  2CNE A;  1V3A A;  5MMZ B;  5AWX A;  3QKP A;  5BZZ A;  1XXP A;  3V0D A;  2CM2 A;  1G7F A;  1NNY A;  3AWE A;  2QDP A;  2H4K A;  1D5R A;  5KA0 A;  3S4E A;  3BRH A;  2VEU A;  1OHC A;  2F6F A;  3A5J A;  1KAK A;  3F9A A;  4JNB A;  1G7G A;  3MOZ A;  4IKC A;  4GE6 A;  3ZM1 A;  4RH9 A;  2J16 B;  2I6M A;  2RF6 A;  5KAD A;  5KA7 A;  2CM3 A;  1R6H A;  1FPR A;  1U25 A;  4GFU A;  2B07 A;  2IMG A;  4ERC A;  1ZCL A;  2E0T A;  3O4S A;  2H4V A;  3U96 A;  5GTJ A;  3NME A;  1OEV A;  2B4O A;  1G4U S;  2I6J A;  2PSZ A;  5I6V A;  5K24 A;  1EEO A;  1A5Y A;  3D44 A;  2JJD A;  2CM7 A;  4RI4 A;  2OUD A;  3EZZ A;  2PA5 A;  1YGU A;  5KA2 A;  2I4H A;  1LQF A;  1X24 A;  1XM2 A;  1ZCK A;  4WTY A;  3ZM0 A;  4DGP A;  2OOQ A;  3D1H A;  3S3E A;  4ZN5 A;  2I75 A;  2CNF A;  2HC1 A;  4H34 A;  2B4S A;  3OMH A;  2CMA A;  2I6I A;  3AWG A;  2FH7 A;  3SME A;  4AZ1 A;  4OHI A;  2R0B A;  1YN9 A;  2WGP A;  1YPT A;  1Q6T A;  4WOH A;  4RI5 A;  1C86 A;  4J51 A;  2HCM A;  2GJT A;  3F81 A;  3EMU A;  3ZMQ A;  3MMJ A;  4QUN A;  4KYR A;  4JBC A;  3F99 A;  1G1H A;  5KAA A;  3O4T A;  1ZC0 A;  1Q6P A;  4JMK A;  4Y2E A;  1XRI A;  2F46 A;  2NV5 A;  1OEU A;  5BZX A;  5K22 A;  1OEM X;  1C85 A;  4R0T A;  4OHL A;  2F6Y A;  4YR8 B;  4R30 A;  3QCB A;  1KAV A;  1Q6J A;  4QBE A;  4ZI4 A;  3QCC A;  3MOW A;  2PBN A;  3AWF A;  1Q6S A;  2QEP A;  1ONZ A;  2PI7 A;  3CM3 A;  3D9C A;  4KYQ A;  4KI9 A;  1YWF A;  2B4U A;  1GFY A;  2H4G A;  3QCF A;  5M43 A;  2SHP A;  1C87 A;  3BLT A;  2I42 A;  2Q05 A;  4PVG A;  4NWF A;  2HNQ A;  4NYH A;  1LAR A;  3I80 A;  3GXG A;  4ICZ A;  3V0J A;  5K23 A;  3D1Q A;  4QAP A;  3PS5 A;  1G1F A;  1AAX A;  2QDM A;  4BPC A;  2I6O A;  3ZM3 A;  3V0F A;  2A3K A;  1NL9 A;  4GFV A;  1T4J A;  3RZ2 A;  2MBC A;  1NWE A;  4GE2 A;  4S0G A;  2F6W A;  4I8N A;  4OHE A;  3S3K A;  1OEO X;  4RKK A;  1ECV A;  2HVL A;  3V0E A;  4B04 A;  4Z6B A;  2I6P A;  3O3L A;  3EU0 A;  2CNI A;  1YFO A;  1EEN A;  1YTN A;  1BZJ A;  2BV5 A;  3V0I A;  1JF7 A;  2VEW A;  4GE5 A;  3ZMP A;  3S3F A;  1YTS A;  2QCJ A;  1RXD A;  2Y96 A;  1PXH A;  2Q47 A;  1Q1M A;  2CMC A;  2P6X A;  2F6Z A;  4MBB A;  2I3U A;  5HDE A;  1XXV A;  2M3V A;  2B4P A;  2CFV A;  4HRF A;  2G59 A;  4OHH A;  1U24 A;  3QCH A;  2A8B A;  3D42 A;  2H04 A;  3QCN A;  2ZN7 A;  2VEX A;  2I3R A;  1C83 A;  1T48 A;  4QUM A;  1PTU A;  4JMJ A;  5KA9 A;  3QCK A;  2YDU A;  1PH0 A;  2BGD A;  4WU2 A;  1YZ4 A;  1I9T A;  2BGE A;  1QZ0 A;  1YTW A;  3QCI A;  1PTY A;  1NZ7 A;  1G4W R;  1LYV A;  3QCM A;  2HY3 A;  4OHD A;  5J8R A;  1ONY A;  1VHR A;  4R0S A;  3ZM2 A;  2NZ6 A;  4D3P A;  1I9S A;  2I4E A;  3O4U A;  4NND A;  2NT7 A;  2CM8 A;  5BUG A;  3OLR A;  3QCE A;  2FJM A;  5K9W A;  3RO1 A;  1OET A;  5KAC A;  3A5K A;  3O5X A;  3S4O A;  1WAX A;  2FJN A;  1PTV A;  2C46 A;  2P4D A;  4DGX A;  5KA3 A;  4D3Q A;  4GWF A;  3QCG A;  5IBM A;  2OC3 A;  2NTA A;  1NWL A;  4HJP A; 
#chains in the Genus database with same CATH topology
 1P31 A;  4RH5 A;  2F6V A;  2WJP A;  2H02 A;  1Q6M A;  2Y67 A;  1QXK A;  1Q6N A;  3RGO A;  2QBP A;  1WCH A;  1FQ1 A;  4C12 A;  2F6T A;  2VOR A;  3D1O A;  5A5E A;  4GRY A;  2C7S A;  2B49 A;  3F41 A;  3EAX A;  4NX8 A;  1G1G A;  5KA8 A;  1BZC A;  1BZH A;  2BIJ A;  2Y1O A;  2CNH A;  2QBR A;  2AZR A;  5BX1 A;  5K25 A;  2DXP A;  2XPC A;  2GCB A;  4QBW A;  4GRZ A;  5KAB A;  2X5O A;  1MKP A;  3F9B A;  2AHS A;  3BLU A;  3EB1 A;  3LJ8 A;  4RHG A;  1PYN A;  2B3O A;  1U26 A;  2F70 A;  1ZZW A;  2I5X A;  2I1Y A;  3QCJ A;  2QDC A;  1PA9 A;  1RPM A;  2GWO A;  4NWG A;  1GQY A;  2J17 A;  1XBO A;  2UUO A;  1L8K A;  2Y2F A;  4ZRT A;  3S3H A;  1NO6 A;  1WRM A;  2VTD A;  3SR9 A;  3V0G A;  3HN7 A;  3QCL A;  2VEV A;  3ZV2 A;  1FGS A;  1P15 A;  2CJZ A;  2H03 A;  4Y14 A;  3N0A A;  3M4U A;  5K9V A;  2HNP A;  3ZL8 A;  2I4G A;  4RDD A;  4D3R A;  1C84 A;  5KA1 A;  1PTT A;  3B7O A;  4GS0 A;  1J4X A;  5EHP A;  2NLK A;  4H1O A;  1SUG A;  1I57 A;  3V0H A;  2HB1 A;  3CWE A;  1PA1 A;  1M3G A;  2ZMM A;  2J16 A;  4TVV A;  2QBS A;  1UAG A;  3GXH A;  1T49 A;  2NT2 A;  2GP0 A;  2HXP A;  3I7Z A;  2ESB A;  2HC2 A;  2VEY A;  1L8G A;  3QCD A;  4PYH A;  2OZ5 A;  4WU3 A;  1EEH A;  2G6Z A;  5EHR A;  5LXQ B;  1OES A;  1OHD A;  3RGQ A;  4QAH A;  5KA4 A;  2F71 A;  2XJA A;  3I36 A;  2BZL A;  1GWZ A;  5IBS A;  1YGR A;  2CMB A;  1JLN A;  4BJO A;  4HJQ A;  1FPZ A;  2VTE A;  2QCT A;  1OHE A;  3BM8 A;  2PT0 A;  4YAA A;  3QKQ A;  3H2X A;  4ZIY A;  2QBQ A;  1C88 A;  2CNG A;  2PQ5 A;  3UAG A;  2CNE A;  1V3A A;  5MMZ B;  5AWX A;  3QKP A;  5BZZ A;  1XXP A;  3V0D A;  2CM2 A;  1G7F A;  4C13 A;  1NNY A;  3AWE A;  2JFF A;  2QDP A;  2H4K A;  1D5R A;  5KA0 A;  3S4E A;  3BRH A;  2VEU A;  1OHC A;  2F6F A;  3A5J A;  1KAK A;  3F9A A;  4JNB A;  1G7G A;  3MOZ A;  4IKC A;  4GE6 A;  3ZM1 A;  4RH9 A;  2J16 B;  2I6M A;  2RF6 A;  5KAD A;  5KA7 A;  2CM3 A;  1R6H A;  1FPR A;  3N2A A;  1U25 A;  4GFU A;  2B07 A;  2IMG A;  4ERC A;  1GG4 A;  2GC5 A;  1ZCL A;  2E0T A;  3O4S A;  2H4V A;  3U96 A;  5GTJ A;  1E0D A;  3NME A;  1OEV A;  2B4O A;  1G4U S;  2I6J A;  2PSZ A;  5I6V A;  5K24 A;  1EEO A;  1A5Y A;  3D44 A;  2JJD A;  2CM7 A;  4RI4 A;  2OUD A;  3EZZ A;  2PA5 A;  1YGU A;  5KA2 A;  2I4H A;  1LQF A;  4QDI A;  1X24 A;  2JFH A;  1W78 A;  1XM2 A;  1ZCK A;  4WTY A;  2Y66 A;  2WTZ A;  3ZM0 A;  4DGP A;  2OOQ A;  3D1H A;  3S3E A;  4ZN5 A;  2I75 A;  2CNF A;  2HC1 A;  4H34 A;  2B4S A;  3OMH A;  2CMA A;  2I6I A;  3AWG A;  2FH7 A;  3SME A;  4CVK A;  4AZ1 A;  4OHI A;  2R0B A;  1YN9 A;  2WGP A;  1YPT A;  1Q6T A;  5A5F A;  4WOH A;  4RI5 A;  1C86 A;  4J51 A;  2HCM A;  2GJT A;  3F81 A;  3EMU A;  3ZMQ A;  3MMJ A;  4QUN A;  2VOS A;  4KYR A;  2UUP A;  4BUC A;  4JBC A;  3F99 A;  1G1H A;  5KAA A;  3O4T A;  1ZC0 A;  1Q6P A;  2GC6 A;  4JMK A;  4Y2E A;  1XRI A;  2F46 A;  3NRS A;  2NV5 A;  1OEU A;  5BZX A;  5K22 A;  1OEM X;  1C85 A;  4R0T A;  4OHL A;  2F6Y A;  2UAG A;  4YR8 B;  4R30 A;  3QCB A;  1KAV A;  1Q6J A;  4QBE A;  4ZI4 A;  3QCC A;  3MOW A;  2PBN A;  3AWF A;  1P3D A;  3PYZ A;  4BUB A;  1Q6S A;  2QEP A;  1ONZ A;  1J6U A;  2PI7 A;  3CM3 A;  3D9C A;  2AM1 A;  4QF5 A;  1O5Z A;  4KYQ A;  4KI9 A;  1YWF A;  2B4U A;  1GFY A;  2H4G A;  3QCF A;  5M43 A;  2SHP A;  1C87 A;  3BLT A;  2I42 A;  2Q05 A;  4PVG A;  4NWF A;  2HNQ A;  4NYH A;  1LAR A;  3I80 A;  3GXG A;  4ICZ A;  4CVM A;  3V0J A;  5K23 A;  3D1Q A;  2AM2 A;  2GCA A;  4QAP A;  3PS5 A;  1G1F A;  1AAX A;  2QDM A;  4BPC A;  2I6O A;  3MVN A;  3ZM3 A;  3V0F A;  2A3K A;  1NL9 A;  4GFV A;  1T4J A;  3RZ2 A;  2MBC A;  1NWE A;  4GE2 A;  4S0G A;  2F6W A;  4I8N A;  4OHE A;  3S3K A;  1OEO X;  4RKK A;  1ECV A;  2HVL A;  3V0E A;  4HV4 A;  4B04 A;  4Z6B A;  2I6P A;  1JBW A;  3O3L A;  3EU0 A;  2CNI A;  1YFO A;  1EEN A;  1YTN A;  1BZJ A;  2BV5 A;  3V0I A;  1JF7 A;  2VEW A;  4GE5 A;  3ZMP A;  3S3F A;  1YTS A;  2QCJ A;  1RXD A;  2Y96 A;  1PXH A;  2Q47 A;  1Q1M A;  2CMC A;  2P6X A;  2F6Z A;  4MBB A;  2I3U A;  5HDE A;  1XXV A;  2M3V A;  2B4P A;  2CFV A;  4HRF A;  2G59 A;  4OHH A;  4CVL A;  2Y68 A;  1U24 A;  3QCH A;  2A8B A;  3D42 A;  2JFG A;  2H04 A;  1JBV A;  3QCN A;  2ZN7 A;  2VEX A;  2I3R A;  1C83 A;  1T48 A;  4QUM A;  1PTU A;  4JMJ A;  3QCZ A;  5KA9 A;  1GQQ A;  3QCK A;  2YDU A;  1PH0 A;  2BGD A;  4WU2 A;  1YZ4 A;  1I9T A;  2BGE A;  1QZ0 A;  1YTW A;  3QCI A;  1PTY A;  1W7K A;  1NZ7 A;  1G4W R;  1LYV A;  3QCM A;  2HY3 A;  4OHD A;  5J8R A;  1ONY A;  1VHR A;  3ZM5 A;  4R0S A;  3ZM2 A;  2NZ6 A;  4D3P A;  1I9S A;  2I4E A;  3O4U A;  3LK7 A;  2F00 A;  4NND A;  2NT7 A;  2CM8 A;  5BUG A;  3OLR A;  3ZM6 A;  4UAG A;  3QCE A;  2FJM A;  5K9W A;  3RO1 A;  1OET A;  5KAC A;  3A5K A;  3O5X A;  1E8C A;  3S4O A;  2P4D A;  1WAX A;  2FJN A;  1PTV A;  2C46 A;  4DGX A;  5KA3 A;  4D3Q A;  4GWF A;  3QCG A;  5IBM A;  2OC3 A;  2NTA A;  1NWL A;  4HJP A; 
#chains in the Genus database with same CATH homology
 4RH5 A;  2F6V A;  2H02 A;  1Q6M A;  1QXK A;  1Q6N A;  3RGO A;  2QBP A;  1WCH A;  1FQ1 A;  2F6T A;  3D1O A;  4GRY A;  2C7S A;  2B49 A;  3F41 A;  3EAX A;  4NX8 A;  1G1G A;  5KA8 A;  1BZC A;  1BZH A;  2BIJ A;  2CNH A;  2QBR A;  2AZR A;  5BX1 A;  5K25 A;  2DXP A;  4QBW A;  4GRZ A;  5KAB A;  1MKP A;  3F9B A;  2AHS A;  3BLU A;  3EB1 A;  3LJ8 A;  4RHG A;  1PYN A;  2B3O A;  1U26 A;  2F70 A;  1ZZW A;  2I5X A;  2I1Y A;  3QCJ A;  2QDC A;  1PA9 A;  1RPM A;  2GWO A;  4NWG A;  2J17 A;  1XBO A;  1L8K A;  2Y2F A;  4ZRT A;  3S3H A;  1NO6 A;  1WRM A;  3SR9 A;  3V0G A;  3QCL A;  2VEV A;  3ZV2 A;  1P15 A;  2CJZ A;  2H03 A;  4Y14 A;  3N0A A;  3M4U A;  5K9V A;  2HNP A;  2I4G A;  4RDD A;  4D3R A;  1C84 A;  5KA1 A;  1PTT A;  3B7O A;  4GS0 A;  1J4X A;  5EHP A;  2NLK A;  4H1O A;  1SUG A;  1I57 A;  3V0H A;  2HB1 A;  3CWE A;  1PA1 A;  1M3G A;  2ZMM A;  2J16 A;  4TVV A;  2QBS A;  3GXH A;  1T49 A;  2NT2 A;  2GP0 A;  2HXP A;  3I7Z A;  2ESB A;  2HC2 A;  2VEY A;  1L8G A;  3QCD A;  4PYH A;  2OZ5 A;  4WU3 A;  5EHR A;  2G6Z A;  5LXQ B;  1OES A;  1OHD A;  3RGQ A;  4QAH A;  5KA4 A;  2F71 A;  3I36 A;  2BZL A;  1GWZ A;  5IBS A;  1YGR A;  2CMB A;  1JLN A;  4BJO A;  4HJQ A;  1FPZ A;  2QCT A;  1OHE A;  3BM8 A;  2PT0 A;  4YAA A;  3QKQ A;  3H2X A;  2QBQ A;  1C88 A;  2CNG A;  2PQ5 A;  2CNE A;  1V3A A;  5MMZ B;  5AWX A;  3QKP A;  5BZZ A;  1XXP A;  3V0D A;  2CM2 A;  1G7F A;  1NNY A;  3AWE A;  2QDP A;  2H4K A;  1D5R A;  5KA0 A;  3S4E A;  3BRH A;  2VEU A;  1OHC A;  2F6F A;  3A5J A;  1KAK A;  3F9A A;  4JNB A;  1G7G A;  3MOZ A;  4IKC A;  4GE6 A;  3ZM1 A;  4RH9 A;  2J16 B;  2I6M A;  2RF6 A;  5KAD A;  5KA7 A;  2CM3 A;  1R6H A;  1FPR A;  1U25 A;  4GFU A;  2B07 A;  2IMG A;  4ERC A;  1ZCL A;  2E0T A;  3O4S A;  2H4V A;  3U96 A;  5GTJ A;  3NME A;  1OEV A;  2B4O A;  1G4U S;  2I6J A;  2PSZ A;  5I6V A;  5K24 A;  1EEO A;  1A5Y A;  3D44 A;  2JJD A;  2CM7 A;  4RI4 A;  2OUD A;  3EZZ A;  2PA5 A;  1YGU A;  5KA2 A;  2I4H A;  1LQF A;  1X24 A;  1XM2 A;  1ZCK A;  4WTY A;  3ZM0 A;  4DGP A;  2OOQ A;  3D1H A;  3S3E A;  4ZN5 A;  2I75 A;  2CNF A;  2HC1 A;  4H34 A;  2B4S A;  3OMH A;  2CMA A;  2I6I A;  3AWG A;  2FH7 A;  3SME A;  4AZ1 A;  4OHI A;  2R0B A;  1YN9 A;  2WGP A;  1YPT A;  1Q6T A;  4WOH A;  4RI5 A;  1C86 A;  4J51 A;  2HCM A;  2GJT A;  3F81 A;  3EMU A;  3ZMQ A;  3MMJ A;  4QUN A;  4KYR A;  4JBC A;  3F99 A;  1G1H A;  5KAA A;  3O4T A;  1ZC0 A;  1Q6P A;  4JMK A;  4Y2E A;  1XRI A;  2F46 A;  2NV5 A;  1OEU A;  5BZX A;  5K22 A;  1OEM X;  1C85 A;  4R0T A;  4OHL A;  2F6Y A;  4YR8 B;  4R30 A;  3QCB A;  1KAV A;  1Q6J A;  4QBE A;  4ZI4 A;  3QCC A;  3MOW A;  2PBN A;  3AWF A;  1Q6S A;  2QEP A;  1ONZ A;  2PI7 A;  3CM3 A;  3D9C A;  4KYQ A;  4KI9 A;  1YWF A;  2B4U A;  1GFY A;  2H4G A;  3QCF A;  5M43 A;  2SHP A;  1C87 A;  3BLT A;  2I42 A;  2Q05 A;  4PVG A;  4NWF A;  2HNQ A;  4NYH A;  1LAR A;  3I80 A;  3GXG A;  4ICZ A;  3V0J A;  5K23 A;  3D1Q A;  4QAP A;  3PS5 A;  1G1F A;  1AAX A;  2QDM A;  4BPC A;  2I6O A;  3ZM3 A;  3V0F A;  2A3K A;  1NL9 A;  4GFV A;  1T4J A;  3RZ2 A;  2MBC A;  1NWE A;  4GE2 A;  4S0G A;  2F6W A;  4I8N A;  4OHE A;  3S3K A;  1OEO X;  4RKK A;  1ECV A;  2HVL A;  3V0E A;  4B04 A;  4Z6B A;  2I6P A;  3O3L A;  3EU0 A;  2CNI A;  1YFO A;  1EEN A;  1YTN A;  1BZJ A;  2BV5 A;  3V0I A;  1JF7 A;  2VEW A;  4GE5 A;  3ZMP A;  3S3F A;  1YTS A;  2QCJ A;  1RXD A;  2Y96 A;  1PXH A;  2Q47 A;  1Q1M A;  2CMC A;  2P6X A;  2F6Z A;  4MBB A;  2I3U A;  5HDE A;  1XXV A;  2M3V A;  2B4P A;  2CFV A;  4HRF A;  2G59 A;  4OHH A;  1U24 A;  3QCH A;  2A8B A;  3D42 A;  2H04 A;  3QCN A;  2ZN7 A;  2VEX A;  2I3R A;  1C83 A;  1T48 A;  4QUM A;  1PTU A;  4JMJ A;  5KA9 A;  3QCK A;  2YDU A;  1PH0 A;  2BGD A;  4WU2 A;  1YZ4 A;  1I9T A;  2BGE A;  1QZ0 A;  1YTW A;  3QCI A;  1PTY A;  1NZ7 A;  1G4W R;  1LYV A;  3QCM A;  2HY3 A;  4OHD A;  5J8R A;  1ONY A;  1VHR A;  4R0S A;  3ZM2 A;  2NZ6 A;  4D3P A;  1I9S A;  2I4E A;  3O4U A;  4NND A;  2NT7 A;  2CM8 A;  5BUG A;  3OLR A;  3QCE A;  2FJM A;  5K9W A;  3RO1 A;  1OET A;  5KAC A;  3A5K A;  3O5X A;  3S4O A;  1WAX A;  2FJN A;  1PTV A;  2C46 A;  2P4D A;  4DGX A;  5KA3 A;  4D3Q A;  4GWF A;  3QCG A;  5IBM A;  2OC3 A;  2NTA A;  1NWL A;  4HJP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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