2CNIA

Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
299
structure length
299
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 104
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cniA00
1G1GA 2GP0A 1ONZA 3RGQA 2HY3A 3S4EA 2P4DA 3F81A 2GWOA 3EMUA 4OHIA 5M43A 3D44A 1FQ1A 2I6MA 4R0TA 2NT2A 2I4HA 1Q6SA 3V0FA 1NNYA 1FPRA 2HC2A 3QCKA 3O4UA 4NNDA 2CNEA 1V3AA 1OHCA 4GS0A 4OHDA 3D1OA 2QDCA 3QCGA 1OESA 4D3QA 2HNPA 5KA8A 1G1HA 2A8BA 1YWFA 1LYVA 1OEUA 2BGEA 4HRFA 2H03A 2R0BA 5KA1A 4KI9A 3V0HA 4QAHA 2I6OA 3EZZA 1GWZA 3EAXA 5IBSA 5K23A 1PA1A 3ZM3A 2G6ZA 1WRMA 4WU2A 3I80A 4RI4A 1T48A 3NMEA 1PYNA 2G59A 2B3OA 2WGPA 2OC3A 3QCLA 1YTNA 4ZI4A 1MKPA 4JMJA 4D3PA 5KAAA 2PSZA 2B4UA 4NYHA 3ZMPA 1L8GA 1XRIA 4WTYA 4TVVA 1ZZWA 2QBQA 2NV5A 4GFUA 4Z6BA 2CNIA 2I6JA 4YR8B 2H4KA 1G4US 2VEUA 2PQ5A 3V0DA 1YGRA 4H34A 2YDUA 2CMBA 3QCIA 1RXDA 1EENA 1JLNA 1PA9A 2I42A 2I5XA 5K22A 3S3FA 5EHRA 5AWXA 4JBCA 2F6YA 1U25A 5BZZA 4JMKA 1ZC0A 3D1QA 1U24A 2HNQA 4I8NA 2QEPA 4J51A 2B49A 1YN9A 5K25A 4S0GA 2SHPA 3QKPA 2VEVA 2F6TA 1ONYA 2PT0A 4PYHA 1VHRA 3QCMA 1I9TA 5K24A 4RHGA 2J17A 3S3HA 2PBNA 2ESBA 4NX8A 3D42A 3ZV2A 3ZM0A 1C88A 3S3KA 3F41A 1L8KA 5KACA 2A3KA 4H1OA 1BZHA 3F9AA 3B7OA 2I4GA 4GE2A 5K9VA 2C46A 4RKKA 3N0AA 1C87A 2F6VA 1R6HA 2CNHA 2NT7A 2QDPA 3O3LA 5GTJA 3O4TA 4GWFA 2HCMA 1J4XA 3QCCA 1PXHA 1NWEA 3V0JA 1GFYA 2H4GA 2QBPA 2F6FA 4GRZA 3F9BA 4GE6A 2P6XA 4GRYA 4ICZA 4NWGA 4IKCA 2NLKA 1BZCA 2B4PA 5LXQB 4JNBA 2B07A 1P15A 3V0GA 5BUGA 2I6PA 1WAXA 2F70A 4YAAA 2CM2A 1D5RA 4PVGA 4AZ1A 2I6IA 5J8RA 2FH7A 1NZ7A 1ZCLA 1Q6NA 1PTVA 1LARA 2CM7A 1Q6TA 2ZN7A 3CWEA 3MMJA 3S4OA 2BZLA 1OEOX 1G7GA 5KABA 1XBOA 1XXVA 2I3UA 2GJTA 2J16B 4QBEA 2NZ6A 1X24A 1G7FA 4QUMA 2I1YA 2Q05A 5KA0A 4D3RA 2VEYA 3SR9A 2Q47A 3GXHA 1NWLA 2J16A 3RO1A 1G4WR 2C7SA 2OOQA 1OHEA 4BPCA 1U26A 1QZ0A 3RGOA 2DXPA 4ZRTA 2CMCA 1PTYA 1Q6JA 2IMGA 1I57A 4OHHA 4RH5A 3ZM1A 2CJZA 4GFVA 2CFVA 3EB1A 5KADA 4QBWA 1ZCKA 3QCDA 5KA2A 4GE5A 3V0IA 4OHEA 1SUGA 4DGXA 4NWFA 2QBSA 2QCTA 5BX1A 5I6VA 4WU3A 4KYQA 4RI5A 3ZMQA 2OUDA 3AWGA 4RH9A 4BJOA 2VEXA 3M4UA 1YFOA 1C86A 2B4OA 4R30A 5KA9A 2VEWA 2M3VA 3QKQA 2HC1A 5MMZB 1I9SA 1OEMX 2BIJA 1YPTA 1Q1MA 1EEOA 2CM8A 1QXKA 5BZXA 1M3GA 2BV5A 1FPZA 2PA5A 3BLTA 2QCJA 3BRHA 2HXPA 3O4SA 3MOWA 2F71A 2FJNA 2QBRA 1WCHA 3BM8A 2F46A 3CM3A 2I3RA 2B4SA 3SMEA 2E0TA 2CNGA 5EHPA 1AAXA 3RZ2A 1YTSA 1BZJA 3OLRA 1OHDA 1XM2A 4HJQA 1LQFA 4ZN5A 3QCEA 3OMHA 1NL9A 3QCNA 4ERCA 1YZ4A 4Y14A 2FJMA 2QDMA 4OHLA 3A5JA 2H04A 2OZ5A 1C83A 1OEVA 1XXPA 2I4EA 3PS5A 4WOHA 4HJPA 4DGPA 1Q6PA 1T49A 1Q6MA 2AZRA 2H02A 3AWEA 2F6ZA 1PTTA 1YTWA 2Y96A 3EU0A 2JJDA 3U96A 5IBMA 1A5YA 4B04A 2H4VA 2MBCA 2HVLA 3F99A 2F6WA 1G1FA 1JF7A 1C85A 1RPMA 3BLUA 3QCFA 3O5XA 1OETA 3GXGA 1ECVA 4QAPA 1C84A 3LJ8A 2CMAA 3D1HA 2PI7A 3QCBA 1YGUA 3H2XA 3S3EA 2NTAA 3QCHA 2HB1A 2BGDA 3V0EA 2ZMMA 2RF6A 3I36A 4KYRA 1T4JA 5KA4A 2Y2FA 3D9CA 1PTUA 3AWFA 1PH0A 1NO6A 3MOZA 5K9WA 4MBBA 3A5KA 1KAKA 3QCJA 4R0SA 4Y2EA 2CNFA 3ZM2A 2AHSA 2I75A 3I7ZA 5HDEA 4RDDA 4QUNA 1KAVA 2CM3A 5KA7A 5KA3A
chains in the Genus database with same CATH superfamily
1G1GA 2GP0A 4ZIYA 1P31A 1ONZA 3RGQA 2HY3A 3NRSA 3S4EA 2P4DA 2WJPA 3F81A 2GWOA 3EMUA 4OHIA 5M43A 3ZM5A 3D44A 1FQ1A 2I6MA 4R0TA 2NT2A 2I4HA 1Q6SA 3V0FA 1NNYA 2Y67A 1FPRA 2HC2A 3QCKA 3O4UA 4NNDA 1GQYA 2Y68A 2CNEA 1V3AA 1OHCA 2JFGA 4GS0A 4OHDA 3D1OA 2QDCA 2JFHA 3QCGA 1OESA 4D3QA 2HNPA 5KA8A 1G1HA 2A8BA 1YWFA 1LYVA 1OEUA 2WTZA 2BGEA 1J6UA 2H03A 4HRFA 3UAGA 2R0BA 5KA1A 2F00A 4KI9A 3V0HA 4QAHA 2I6OA 3EZZA 2GCBA 1GWZA 3EAXA 5IBSA 5K23A 1E8CA 1PA1A 3ZM3A 2G6ZA 1WRMA 4WU2A 3I80A 4RI4A 1T48A 3NMEA 1PYNA 2G59A 2B3OA 2WGPA 2OC3A 3QCLA 1YTNA 4ZI4A 1MKPA 4JMJA 4D3PA 5KAAA 2PSZA 2B4UA 4NYHA 3ZMPA 2UUOA 4BUBA 1L8GA 1XRIA 4WTYA 4TVVA 1ZZWA 2QBQA 2NV5A 4GFUA 4Z6BA 2CNIA 2I6JA 4YR8B 2H4KA 1G4US 2VEUA 2PQ5A 3LK7A 3HN7A 3V0DA 4CVKA 2VOSA 1YGRA 1P3DA 4H34A 2YDUA 2CMBA 3QCIA 1RXDA 1EENA 1JLNA 1JBVA 1PA9A 2I42A 2I5XA 5K22A 3S3FA 5EHRA 5AWXA 4JBCA 2F6YA 1U25A 5BZZA 4JMKA 1ZC0A 3D1QA 1U24A 2HNQA 4I8NA 2QEPA 4J51A 2B49A 1YN9A 5K25A 1FGSA 4S0GA 2SHPA 3QKPA 2VEVA 2F6TA 1ONYA 2PT0A 4PYHA 4BUCA 3ZL8A 1VHRA 3QCMA 1O5ZA 1I9TA 5K24A 4RHGA 2J17A 3S3HA 2PBNA 2ESBA 4NX8A 3D42A 3ZV2A 3ZM0A 1C88A 2X5OA 3S3KA 3F41A 1L8KA 5KACA 2A3KA 4H1OA 1BZHA 3F9AA 3B7OA 2I4GA 4GE2A 5K9VA 2C46A 4RKKA 2GC5A 2VTEA 3N0AA 1C87A 2F6VA 1R6HA 2CNHA 2NT7A 2QDPA 3O3LA 2JFFA 5GTJA 2XPCA 3O4TA 4GWFA 2HCMA 1J4XA 3QCCA 1PXHA 1NWEA 3V0JA 1GFYA 2H4GA 2QBPA 2F6FA 4GRZA 3F9BA 4GE6A 2GC6A 2P6XA 4C13A 4GRYA 4ICZA 5A5FA 4NWGA 4IKCA 2NLKA 1BZCA 4UAGA 2B4PA 5LXQB 4JNBA 2AM2A 4QDIA 2B07A 1P15A 3V0GA 3ZM6A 5BUGA 2I6PA 1WAXA 2F70A 4YAAA 2CM2A 1D5RA 4PVGA 4AZ1A 2I6IA 5J8RA 2FH7A 1NZ7A 1ZCLA 1Q6NA 1PTVA 1LARA 2CM7A 1Q6TA 2ZN7A 3CWEA 3MMJA 3S4OA 2BZLA 1OEOX 1G7GA 5KABA 1XBOA 1XXVA 2I3UA 2GJTA 1E0DA 2J16B 4QBEA 2NZ6A 1X24A 1G7FA 4QUMA 2I1YA 2Q05A 5KA0A 4D3RA 2VEYA 3SR9A 2Q47A 3GXHA 1NWLA 2J16A 3RO1A 1G4WR 2C7SA 2OOQA 1OHEA 4BPCA 4HV4A 1U26A 1QZ0A 3RGOA 2DXPA 4ZRTA 2CMCA 1PTYA 1Q6JA 2IMGA 1I57A 4OHHA 4RH5A 3ZM1A 2CJZA 4GFVA 2CFVA 3EB1A 5KADA 2VORA 4QBWA 2XJAA 1ZCKA 3QCDA 5KA2A 4GE5A 3V0IA 4OHEA 1SUGA 4DGXA 4NWFA 2QBSA 2QCTA 5BX1A 3PYZA 5I6VA 4WU3A 4KYQA 4RI5A 3ZMQA 2OUDA 3AWGA 4RH9A 4BJOA 1UAGA 2VEXA 3M4UA 1YFOA 1C86A 2B4OA 2GCAA 4R30A 5KA9A 1W78A 2VEWA 2M3VA 2UUPA 3QKQA 2HC1A 5MMZB 1I9SA 1OEMX 5A5EA 2BIJA 1YPTA 1Q1MA 1EEOA 2CM8A 1QXKA 5BZXA 1M3GA 2BV5A 1FPZA 2PA5A 3BLTA 2QCJA 3BRHA 2HXPA 3O4SA 4QF5A 3MOWA 2F71A 2FJNA 2QBRA 1WCHA 3BM8A 2F46A 3CM3A 2I3RA 2B4SA 3SMEA 2E0TA 2CNGA 5EHPA 4C12A 1AAXA 3RZ2A 1YTSA 1BZJA 3OLRA 1OHDA 1XM2A 4HJQA 1LQFA 4ZN5A 1GQQA 3QCEA 3OMHA 1NL9A 3QCNA 4ERCA 1YZ4A 4Y14A 2FJMA 2QDMA 4OHLA 3A5JA 2H04A 2UAGA 2OZ5A 1C83A 1OEVA 1XXPA 2I4EA 3PS5A 4WOHA 4HJPA 4DGPA 1Q6PA 1T49A 1Q6MA 2AZRA 2H02A 3AWEA 2F6ZA 1EEHA 1PTTA 1YTWA 3QCZA 2Y96A 3N2AA 3EU0A 2JJDA 3U96A 5IBMA 1A5YA 4B04A 2H4VA 2MBCA 2HVLA 3F99A 2F6WA 1G1FA 1JF7A 1C85A 1RPMA 3BLUA 3QCFA 3O5XA 1OETA 3GXGA 1ECVA 4QAPA 1JBWA 1C84A 3LJ8A 2CMAA 3D1HA 4CVMA 2PI7A 4CVLA 3MVNA 3QCBA 1GG4A 1YGUA 3H2XA 3S3EA 2NTAA 3QCHA 2AM1A 2HB1A 1W7KA 2BGDA 3V0EA 2ZMMA 2RF6A 3I36A 4KYRA 1T4JA 5KA4A 2Y2FA 2VTDA 3D9CA 1PTUA 2Y66A 3AWFA 1PH0A 1NO6A 3MOZA 5K9WA 4MBBA 3A5KA 1KAKA 3QCJA 4R0SA 4Y2EA 2CNFA 3ZM2A 2AHSA 2I75A 3I7ZA 5HDEA 4RDDA 2Y1OA 4QUNA 1KAVA 2CM3A 5KA7A 5KA3A
chains in the Genus database with same CATH topology
1G1GA 2GP0A 1ONZA 3RGQA 2HY3A 3S4EA 2P4DA 3F81A 2GWOA 3EMUA 4OHIA 5M43A 3D44A 1FQ1A 2I6MA 4R0TA 2NT2A 2I4HA 1Q6SA 3V0FA 1NNYA 1FPRA 2HC2A 3QCKA 3O4UA 4NNDA 2CNEA 1V3AA 1OHCA 4GS0A 4OHDA 3D1OA 2QDCA 3QCGA 1OESA 4D3QA 2HNPA 5KA8A 1G1HA 2A8BA 1YWFA 1LYVA 1OEUA 2BGEA 4HRFA 2H03A 2R0BA 5KA1A 4KI9A 3V0HA 4QAHA 2I6OA 3EZZA 1GWZA 3EAXA 5IBSA 5K23A 1PA1A 3ZM3A 2G6ZA 1WRMA 4WU2A 3I80A 4RI4A 1T48A 3NMEA 1PYNA 2G59A 2B3OA 2WGPA 2OC3A 3QCLA 1YTNA 4ZI4A 1MKPA 4JMJA 4D3PA 5KAAA 2PSZA 2B4UA 4NYHA 3ZMPA 1L8GA 1XRIA 4WTYA 4TVVA 1ZZWA 2QBQA 2NV5A 4GFUA 4Z6BA 2CNIA 2I6JA 4YR8B 2H4KA 1G4US 2VEUA 2PQ5A 3V0DA 1YGRA 4H34A 2YDUA 2CMBA 3QCIA 1RXDA 1EENA 1JLNA 1PA9A 2I42A 2I5XA 5K22A 3S3FA 5EHRA 5AWXA 4JBCA 2F6YA 1U25A 5BZZA 4JMKA 1ZC0A 3D1QA 1U24A 2HNQA 4I8NA 2QEPA 4J51A 2B49A 1YN9A 5K25A 4S0GA 2SHPA 3QKPA 2VEVA 2F6TA 1ONYA 2PT0A 4PYHA 1VHRA 3QCMA 1I9TA 5K24A 4RHGA 2J17A 3S3HA 2PBNA 2ESBA 4NX8A 3D42A 3ZV2A 3ZM0A 1C88A 3S3KA 3F41A 1L8KA 5KACA 2A3KA 4H1OA 1BZHA 3F9AA 3B7OA 2I4GA 4GE2A 5K9VA 2C46A 4RKKA 3N0AA 1C87A 2F6VA 1R6HA 2CNHA 2NT7A 2QDPA 3O3LA 5GTJA 3O4TA 4GWFA 2HCMA 1J4XA 3QCCA 1PXHA 1NWEA 3V0JA 1GFYA 2H4GA 2QBPA 2F6FA 4GRZA 3F9BA 4GE6A 2P6XA 4GRYA 4ICZA 4NWGA 4IKCA 2NLKA 1BZCA 2B4PA 5LXQB 4JNBA 2B07A 1P15A 3V0GA 5BUGA 2I6PA 1WAXA 2F70A 4YAAA 2CM2A 1D5RA 4PVGA 4AZ1A 2I6IA 5J8RA 2FH7A 1NZ7A 1ZCLA 1Q6NA 1PTVA 1LARA 2CM7A 1Q6TA 2ZN7A 3CWEA 3MMJA 3S4OA 2BZLA 1OEOX 1G7GA 5KABA 1XBOA 1XXVA 2I3UA 2GJTA 2J16B 4QBEA 2NZ6A 1X24A 1G7FA 4QUMA 2I1YA 2Q05A 5KA0A 4D3RA 2VEYA 3SR9A 2Q47A 3GXHA 1NWLA 2J16A 3RO1A 1G4WR 2C7SA 2OOQA 1OHEA 4BPCA 1U26A 1QZ0A 3RGOA 2DXPA 4ZRTA 2CMCA 1PTYA 1Q6JA 2IMGA 1I57A 4OHHA 4RH5A 3ZM1A 2CJZA 4GFVA 2CFVA 3EB1A 5KADA 4QBWA 1ZCKA 3QCDA 5KA2A 4GE5A 3V0IA 4OHEA 1SUGA 4DGXA 4NWFA 2QBSA 2QCTA 5BX1A 5I6VA 4WU3A 4KYQA 4RI5A 3ZMQA 2OUDA 3AWGA 4RH9A 4BJOA 2VEXA 3M4UA 1YFOA 1C86A 2B4OA 4R30A 5KA9A 2VEWA 2M3VA 3QKQA 2HC1A 5MMZB 1I9SA 1OEMX 2BIJA 1YPTA 1Q1MA 1EEOA 2CM8A 1QXKA 5BZXA 1M3GA 2BV5A 1FPZA 2PA5A 3BLTA 2QCJA 3BRHA 2HXPA 3O4SA 3MOWA 2F71A 2FJNA 2QBRA 1WCHA 3BM8A 2F46A 3CM3A 2I3RA 2B4SA 3SMEA 2E0TA 2CNGA 5EHPA 1AAXA 3RZ2A 1YTSA 1BZJA 3OLRA 1OHDA 1XM2A 4HJQA 1LQFA 4ZN5A 3QCEA 3OMHA 1NL9A 3QCNA 4ERCA 1YZ4A 4Y14A 2FJMA 2QDMA 4OHLA 3A5JA 2H04A 2OZ5A 1C83A 1OEVA 1XXPA 2I4EA 3PS5A 4WOHA 4HJPA 4DGPA 1Q6PA 1T49A 1Q6MA 2AZRA 2H02A 3AWEA 2F6ZA 1PTTA 1YTWA 2Y96A 3EU0A 2JJDA 3U96A 5IBMA 1A5YA 4B04A 2H4VA 2MBCA 2HVLA 3F99A 2F6WA 1G1FA 1JF7A 1C85A 1RPMA 3BLUA 3QCFA 3O5XA 1OETA 3GXGA 1ECVA 4QAPA 1C84A 3LJ8A 2CMAA 3D1HA 2PI7A 3QCBA 1YGUA 3H2XA 3S3EA 2NTAA 3QCHA 2HB1A 2BGDA 3V0EA 2ZMMA 2RF6A 3I36A 4KYRA 1T4JA 5KA4A 2Y2FA 3D9CA 1PTUA 3AWFA 1PH0A 1NO6A 3MOZA 5K9WA 4MBBA 3A5KA 1KAKA 3QCJA 4R0SA 4Y2EA 2CNFA 3ZM2A 2AHSA 2I75A 3I7ZA 5HDEA 4RDDA 4QUNA 1KAVA 2CM3A 5KA7A 5KA3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G1G A;  2GP0 A;  1ONZ A;  3RGQ A;  2HY3 A;  3S4E A;  2P4D A;  3F81 A;  2GWO A;  3EMU A;  4OHI A;  5M43 A;  3D44 A;  1FQ1 A;  2I6M A;  4R0T A;  2NT2 A;  2I4H A;  1Q6S A;  3V0F A;  1NNY A;  1FPR A;  2HC2 A;  3QCK A;  3O4U A;  4NND A;  2CNE A;  1V3A A;  1OHC A;  4GS0 A;  4OHD A;  3D1O A;  2QDC A;  3QCG A;  1OES A;  4D3Q A;  2HNP A;  5KA8 A;  1G1H A;  2A8B A;  1YWF A;  1LYV A;  1OEU A;  2BGE A;  4HRF A;  2H03 A;  2R0B A;  5KA1 A;  4KI9 A;  3V0H A;  4QAH A;  2I6O A;  3EZZ A;  1GWZ A;  3EAX A;  5IBS A;  5K23 A;  1PA1 A;  3ZM3 A;  2G6Z A;  1WRM A;  4WU2 A;  3I80 A;  4RI4 A;  1T48 A;  3NME A;  1PYN A;  2G59 A;  2B3O A;  2WGP A;  2OC3 A;  3QCL A;  1YTN A;  4ZI4 A;  1MKP A;  4JMJ A;  4D3P A;  5KAA A;  2PSZ A;  2B4U A;  4NYH A;  3ZMP A;  1L8G A;  1XRI A;  4WTY A;  4TVV A;  1ZZW A;  2QBQ A;  2NV5 A;  4GFU A;  4Z6B A;  2CNI A;  2I6J A;  4YR8 B;  2H4K A;  1G4U S;  2VEU A;  2PQ5 A;  3V0D A;  1YGR A;  4H34 A;  2YDU A;  2CMB A;  3QCI A;  1RXD A;  1EEN A;  1JLN A;  1PA9 A;  2I42 A;  2I5X A;  5K22 A;  3S3F A;  5EHR A;  5AWX A;  4JBC A;  2F6Y A;  1U25 A;  5BZZ A;  4JMK A;  1ZC0 A;  3D1Q A;  1U24 A;  2HNQ A;  4I8N A;  2QEP A;  4J51 A;  2B49 A;  1YN9 A;  5K25 A;  4S0G A;  2SHP A;  3QKP A;  2VEV A;  2F6T A;  1ONY A;  2PT0 A;  4PYH A;  1VHR A;  3QCM A;  1I9T A;  5K24 A;  4RHG A;  2J17 A;  3S3H A;  2PBN A;  2ESB A;  4NX8 A;  3D42 A;  3ZV2 A;  3ZM0 A;  1C88 A;  3S3K A;  3F41 A;  1L8K A;  5KAC A;  2A3K A;  4H1O A;  1BZH A;  3F9A A;  3B7O A;  2I4G A;  4GE2 A;  5K9V A;  2C46 A;  4RKK A;  3N0A A;  1C87 A;  2F6V A;  1R6H A;  2CNH A;  2NT7 A;  2QDP A;  3O3L A;  5GTJ A;  3O4T A;  4GWF A;  2HCM A;  1J4X A;  3QCC A;  1PXH A;  1NWE A;  3V0J A;  1GFY A;  2H4G A;  2QBP A;  2F6F A;  4GRZ A;  3F9B A;  4GE6 A;  2P6X A;  4GRY A;  4ICZ A;  4NWG A;  4IKC A;  2NLK A;  1BZC A;  2B4P A;  5LXQ B;  4JNB A;  2B07 A;  1P15 A;  3V0G A;  5BUG A;  2I6P A;  1WAX A;  2F70 A;  4YAA A;  2CM2 A;  1D5R A;  4PVG A;  4AZ1 A;  2I6I A;  5J8R A;  2FH7 A;  1NZ7 A;  1ZCL A;  1Q6N A;  1PTV A;  1LAR A;  2CM7 A;  1Q6T A;  2ZN7 A;  3CWE A;  3MMJ A;  3S4O A;  2BZL A;  1OEO X;  1G7G A;  5KAB A;  1XBO A;  1XXV A;  2I3U A;  2GJT A;  2J16 B;  4QBE A;  2NZ6 A;  1X24 A;  1G7F A;  4QUM A;  2I1Y A;  2Q05 A;  5KA0 A;  4D3R A;  2VEY A;  3SR9 A;  2Q47 A;  3GXH A;  1NWL A;  2J16 A;  3RO1 A;  1G4W R;  2C7S A;  2OOQ A;  1OHE A;  4BPC A;  1U26 A;  1QZ0 A;  3RGO A;  2DXP A;  4ZRT A;  2CMC A;  1PTY A;  1Q6J A;  2IMG A;  1I57 A;  4OHH A;  4RH5 A;  3ZM1 A;  2CJZ A;  4GFV A;  2CFV A;  3EB1 A;  5KAD A;  4QBW A;  1ZCK A;  3QCD A;  5KA2 A;  4GE5 A;  3V0I A;  4OHE A;  1SUG A;  4DGX A;  4NWF A;  2QBS A;  2QCT A;  5BX1 A;  5I6V A;  4WU3 A;  4KYQ A;  4RI5 A;  3ZMQ A;  2OUD A;  3AWG A;  4RH9 A;  4BJO A;  2VEX A;  3M4U A;  1YFO A;  1C86 A;  2B4O A;  4R30 A;  5KA9 A;  2VEW A;  2M3V A;  3QKQ A;  2HC1 A;  5MMZ B;  1I9S A;  1OEM X;  2BIJ A;  1YPT A;  1Q1M A;  1EEO A;  2CM8 A;  1QXK A;  5BZX A;  1M3G A;  2BV5 A;  1FPZ A;  2PA5 A;  3BLT A;  2QCJ A;  3BRH A;  2HXP A;  3O4S A;  3MOW A;  2F71 A;  2FJN A;  2QBR A;  1WCH A;  3BM8 A;  2F46 A;  3CM3 A;  2I3R A;  2B4S A;  3SME A;  2E0T A;  2CNG A;  5EHP A;  1AAX A;  3RZ2 A;  1YTS A;  1BZJ A;  3OLR A;  1OHD A;  1XM2 A;  4HJQ A;  1LQF A;  4ZN5 A;  3QCE A;  3OMH A;  1NL9 A;  3QCN A;  4ERC A;  1YZ4 A;  4Y14 A;  2FJM A;  2QDM A;  4OHL A;  3A5J A;  2H04 A;  2OZ5 A;  1C83 A;  1OEV A;  1XXP A;  2I4E A;  3PS5 A;  4WOH A;  4HJP A;  4DGP A;  1Q6P A;  1T49 A;  1Q6M A;  2AZR A;  2H02 A;  3AWE A;  2F6Z A;  1PTT A;  1YTW A;  2Y96 A;  3EU0 A;  2JJD A;  3U96 A;  5IBM A;  1A5Y A;  4B04 A;  2H4V A;  2MBC A;  2HVL A;  3F99 A;  2F6W A;  1G1F A;  1JF7 A;  1C85 A;  1RPM A;  3BLU A;  3QCF A;  3O5X A;  1OET A;  3GXG A;  1ECV A;  4QAP A;  1C84 A;  3LJ8 A;  2CMA A;  3D1H A;  2PI7 A;  3QCB A;  1YGU A;  3H2X A;  3S3E A;  2NTA A;  3QCH A;  2HB1 A;  2BGD A;  3V0E A;  2ZMM A;  2RF6 A;  3I36 A;  4KYR A;  1T4J A;  5KA4 A;  2Y2F A;  3D9C A;  1PTU A;  3AWF A;  1PH0 A;  1NO6 A;  3MOZ A;  5K9W A;  4MBB A;  3A5K A;  1KAK A;  3QCJ A;  4R0S A;  4Y2E A;  2CNF A;  3ZM2 A;  2AHS A;  2I75 A;  3I7Z A;  5HDE A;  4RDD A;  4QUN A;  1KAV A;  2CM3 A;  5KA7 A;  5KA3 A; 
#chains in the Genus database with same CATH topology
 1G1G A;  2GP0 A;  4ZIY A;  1P31 A;  1ONZ A;  3RGQ A;  2HY3 A;  3NRS A;  3S4E A;  2P4D A;  2WJP A;  3F81 A;  2GWO A;  3EMU A;  4OHI A;  5M43 A;  3ZM5 A;  3D44 A;  1FQ1 A;  2I6M A;  4R0T A;  2NT2 A;  2I4H A;  1Q6S A;  3V0F A;  1NNY A;  2Y67 A;  1FPR A;  2HC2 A;  3QCK A;  3O4U A;  4NND A;  1GQY A;  2Y68 A;  2CNE A;  1V3A A;  1OHC A;  2JFG A;  4GS0 A;  4OHD A;  3D1O A;  2QDC A;  2JFH A;  3QCG A;  1OES A;  4D3Q A;  2HNP A;  5KA8 A;  1G1H A;  2A8B A;  1YWF A;  1LYV A;  1OEU A;  2WTZ A;  2BGE A;  1J6U A;  2H03 A;  4HRF A;  3UAG A;  2R0B A;  5KA1 A;  2F00 A;  4KI9 A;  3V0H A;  4QAH A;  2I6O A;  3EZZ A;  2GCB A;  1GWZ A;  3EAX A;  5IBS A;  5K23 A;  1E8C A;  1PA1 A;  3ZM3 A;  2G6Z A;  1WRM A;  4WU2 A;  3I80 A;  4RI4 A;  1T48 A;  3NME A;  1PYN A;  2G59 A;  2B3O A;  2WGP A;  2OC3 A;  3QCL A;  1YTN A;  4ZI4 A;  1MKP A;  4JMJ A;  4D3P A;  5KAA A;  2PSZ A;  2B4U A;  4NYH A;  3ZMP A;  2UUO A;  4BUB A;  1L8G A;  1XRI A;  4WTY A;  4TVV A;  1ZZW A;  2QBQ A;  2NV5 A;  4GFU A;  4Z6B A;  2CNI A;  2I6J A;  4YR8 B;  2H4K A;  1G4U S;  2VEU A;  2PQ5 A;  3LK7 A;  3HN7 A;  3V0D A;  4CVK A;  2VOS A;  1YGR A;  1P3D A;  4H34 A;  2YDU A;  2CMB A;  3QCI A;  1RXD A;  1EEN A;  1JLN A;  1JBV A;  1PA9 A;  2I42 A;  2I5X A;  5K22 A;  3S3F A;  5EHR A;  5AWX A;  4JBC A;  2F6Y A;  1U25 A;  5BZZ A;  4JMK A;  1ZC0 A;  3D1Q A;  1U24 A;  2HNQ A;  4I8N A;  2QEP A;  4J51 A;  2B49 A;  1YN9 A;  5K25 A;  1FGS A;  4S0G A;  2SHP A;  3QKP A;  2VEV A;  2F6T A;  1ONY A;  2PT0 A;  4PYH A;  4BUC A;  3ZL8 A;  1VHR A;  3QCM A;  1O5Z A;  1I9T A;  5K24 A;  4RHG A;  2J17 A;  3S3H A;  2PBN A;  2ESB A;  4NX8 A;  3D42 A;  3ZV2 A;  3ZM0 A;  1C88 A;  2X5O A;  3S3K A;  3F41 A;  1L8K A;  5KAC A;  2A3K A;  4H1O A;  1BZH A;  3F9A A;  3B7O A;  2I4G A;  4GE2 A;  5K9V A;  2C46 A;  4RKK A;  2GC5 A;  2VTE A;  3N0A A;  1C87 A;  2F6V A;  1R6H A;  2CNH A;  2NT7 A;  2QDP A;  3O3L A;  2JFF A;  5GTJ A;  2XPC A;  3O4T A;  4GWF A;  2HCM A;  1J4X A;  3QCC A;  1PXH A;  1NWE A;  3V0J A;  1GFY A;  2H4G A;  2QBP A;  2F6F A;  4GRZ A;  3F9B A;  4GE6 A;  2GC6 A;  2P6X A;  4C13 A;  4GRY A;  4ICZ A;  5A5F A;  4NWG A;  4IKC A;  2NLK A;  1BZC A;  4UAG A;  2B4P A;  5LXQ B;  4JNB A;  2AM2 A;  4QDI A;  2B07 A;  1P15 A;  3V0G A;  3ZM6 A;  5BUG A;  2I6P A;  1WAX A;  2F70 A;  4YAA A;  2CM2 A;  1D5R A;  4PVG A;  4AZ1 A;  2I6I A;  5J8R A;  2FH7 A;  1NZ7 A;  1ZCL A;  1Q6N A;  1PTV A;  1LAR A;  2CM7 A;  1Q6T A;  2ZN7 A;  3CWE A;  3MMJ A;  3S4O A;  2BZL A;  1OEO X;  1G7G A;  5KAB A;  1XBO A;  1XXV A;  2I3U A;  2GJT A;  1E0D A;  2J16 B;  4QBE A;  2NZ6 A;  1X24 A;  1G7F A;  4QUM A;  2I1Y A;  2Q05 A;  5KA0 A;  4D3R A;  2VEY A;  3SR9 A;  2Q47 A;  3GXH A;  1NWL A;  2J16 A;  3RO1 A;  1G4W R;  2C7S A;  2OOQ A;  1OHE A;  4BPC A;  4HV4 A;  1U26 A;  1QZ0 A;  3RGO A;  2DXP A;  4ZRT A;  2CMC A;  1PTY A;  1Q6J A;  2IMG A;  1I57 A;  4OHH A;  4RH5 A;  3ZM1 A;  2CJZ A;  4GFV A;  2CFV A;  3EB1 A;  5KAD A;  2VOR A;  4QBW A;  2XJA A;  1ZCK A;  3QCD A;  5KA2 A;  4GE5 A;  3V0I A;  4OHE A;  1SUG A;  4DGX A;  4NWF A;  2QBS A;  2QCT A;  5BX1 A;  3PYZ A;  5I6V A;  4WU3 A;  4KYQ A;  4RI5 A;  3ZMQ A;  2OUD A;  3AWG A;  4RH9 A;  4BJO A;  1UAG A;  2VEX A;  3M4U A;  1YFO A;  1C86 A;  2B4O A;  2GCA A;  4R30 A;  5KA9 A;  1W78 A;  2VEW A;  2M3V A;  2UUP A;  3QKQ A;  2HC1 A;  5MMZ B;  1I9S A;  1OEM X;  5A5E A;  2BIJ A;  1YPT A;  1Q1M A;  1EEO A;  2CM8 A;  1QXK A;  5BZX A;  1M3G A;  2BV5 A;  1FPZ A;  2PA5 A;  3BLT A;  2QCJ A;  3BRH A;  2HXP A;  3O4S A;  4QF5 A;  3MOW A;  2F71 A;  2FJN A;  2QBR A;  1WCH A;  3BM8 A;  2F46 A;  3CM3 A;  2I3R A;  2B4S A;  3SME A;  2E0T A;  2CNG A;  5EHP A;  4C12 A;  1AAX A;  3RZ2 A;  1YTS A;  1BZJ A;  3OLR A;  1OHD A;  1XM2 A;  4HJQ A;  1LQF A;  4ZN5 A;  1GQQ A;  3QCE A;  3OMH A;  1NL9 A;  3QCN A;  4ERC A;  1YZ4 A;  4Y14 A;  2FJM A;  2QDM A;  4OHL A;  3A5J A;  2H04 A;  2UAG A;  2OZ5 A;  1C83 A;  1OEV A;  1XXP A;  2I4E A;  3PS5 A;  4WOH A;  4HJP A;  4DGP A;  1Q6P A;  1T49 A;  1Q6M A;  2AZR A;  2H02 A;  3AWE A;  2F6Z A;  1EEH A;  1PTT A;  1YTW A;  3QCZ A;  2Y96 A;  3N2A A;  3EU0 A;  2JJD A;  3U96 A;  5IBM A;  1A5Y A;  4B04 A;  2H4V A;  2MBC A;  2HVL A;  3F99 A;  2F6W A;  1G1F A;  1JF7 A;  1C85 A;  1RPM A;  3BLU A;  3QCF A;  3O5X A;  1OET A;  3GXG A;  1ECV A;  4QAP A;  1JBW A;  1C84 A;  3LJ8 A;  2CMA A;  3D1H A;  4CVM A;  2PI7 A;  4CVL A;  3MVN A;  3QCB A;  1GG4 A;  1YGU A;  3H2X A;  3S3E A;  2NTA A;  3QCH A;  2AM1 A;  2HB1 A;  1W7K A;  2BGD A;  3V0E A;  2ZMM A;  2RF6 A;  3I36 A;  4KYR A;  1T4J A;  5KA4 A;  2Y2F A;  2VTD A;  3D9C A;  1PTU A;  2Y66 A;  3AWF A;  1PH0 A;  1NO6 A;  3MOZ A;  5K9W A;  4MBB A;  3A5K A;  1KAK A;  3QCJ A;  4R0S A;  4Y2E A;  2CNF A;  3ZM2 A;  2AHS A;  2I75 A;  3I7Z A;  5HDE A;  4RDD A;  2Y1O A;  4QUN A;  1KAV A;  2CM3 A;  5KA7 A;  5KA3 A; 
#chains in the Genus database with same CATH homology
 1G1G A;  2GP0 A;  1ONZ A;  3RGQ A;  2HY3 A;  3S4E A;  2P4D A;  3F81 A;  2GWO A;  3EMU A;  4OHI A;  5M43 A;  3D44 A;  1FQ1 A;  2I6M A;  4R0T A;  2NT2 A;  2I4H A;  1Q6S A;  3V0F A;  1NNY A;  1FPR A;  2HC2 A;  3QCK A;  3O4U A;  4NND A;  2CNE A;  1V3A A;  1OHC A;  4GS0 A;  4OHD A;  3D1O A;  2QDC A;  3QCG A;  1OES A;  4D3Q A;  2HNP A;  5KA8 A;  1G1H A;  2A8B A;  1YWF A;  1LYV A;  1OEU A;  2BGE A;  4HRF A;  2H03 A;  2R0B A;  5KA1 A;  4KI9 A;  3V0H A;  4QAH A;  2I6O A;  3EZZ A;  1GWZ A;  3EAX A;  5IBS A;  5K23 A;  1PA1 A;  3ZM3 A;  2G6Z A;  1WRM A;  4WU2 A;  3I80 A;  4RI4 A;  1T48 A;  3NME A;  1PYN A;  2G59 A;  2B3O A;  2WGP A;  2OC3 A;  3QCL A;  1YTN A;  4ZI4 A;  1MKP A;  4JMJ A;  4D3P A;  5KAA A;  2PSZ A;  2B4U A;  4NYH A;  3ZMP A;  1L8G A;  1XRI A;  4WTY A;  4TVV A;  1ZZW A;  2QBQ A;  2NV5 A;  4GFU A;  4Z6B A;  2CNI A;  2I6J A;  4YR8 B;  2H4K A;  1G4U S;  2VEU A;  2PQ5 A;  3V0D A;  1YGR A;  4H34 A;  2YDU A;  2CMB A;  3QCI A;  1RXD A;  1EEN A;  1JLN A;  1PA9 A;  2I42 A;  2I5X A;  5K22 A;  3S3F A;  5EHR A;  5AWX A;  4JBC A;  2F6Y A;  1U25 A;  5BZZ A;  4JMK A;  1ZC0 A;  3D1Q A;  1U24 A;  2HNQ A;  4I8N A;  2QEP A;  4J51 A;  2B49 A;  1YN9 A;  5K25 A;  4S0G A;  2SHP A;  3QKP A;  2VEV A;  2F6T A;  1ONY A;  2PT0 A;  4PYH A;  1VHR A;  3QCM A;  1I9T A;  5K24 A;  4RHG A;  2J17 A;  3S3H A;  2PBN A;  2ESB A;  4NX8 A;  3D42 A;  3ZV2 A;  3ZM0 A;  1C88 A;  3S3K A;  3F41 A;  1L8K A;  5KAC A;  2A3K A;  4H1O A;  1BZH A;  3F9A A;  3B7O A;  2I4G A;  4GE2 A;  5K9V A;  2C46 A;  4RKK A;  3N0A A;  1C87 A;  2F6V A;  1R6H A;  2CNH A;  2NT7 A;  2QDP A;  3O3L A;  5GTJ A;  3O4T A;  4GWF A;  2HCM A;  1J4X A;  3QCC A;  1PXH A;  1NWE A;  3V0J A;  1GFY A;  2H4G A;  2QBP A;  2F6F A;  4GRZ A;  3F9B A;  4GE6 A;  2P6X A;  4GRY A;  4ICZ A;  4NWG A;  4IKC A;  2NLK A;  1BZC A;  2B4P A;  5LXQ B;  4JNB A;  2B07 A;  1P15 A;  3V0G A;  5BUG A;  2I6P A;  1WAX A;  2F70 A;  4YAA A;  2CM2 A;  1D5R A;  4PVG A;  4AZ1 A;  2I6I A;  5J8R A;  2FH7 A;  1NZ7 A;  1ZCL A;  1Q6N A;  1PTV A;  1LAR A;  2CM7 A;  1Q6T A;  2ZN7 A;  3CWE A;  3MMJ A;  3S4O A;  2BZL A;  1OEO X;  1G7G A;  5KAB A;  1XBO A;  1XXV A;  2I3U A;  2GJT A;  2J16 B;  4QBE A;  2NZ6 A;  1X24 A;  1G7F A;  4QUM A;  2I1Y A;  2Q05 A;  5KA0 A;  4D3R A;  2VEY A;  3SR9 A;  2Q47 A;  3GXH A;  1NWL A;  2J16 A;  3RO1 A;  1G4W R;  2C7S A;  2OOQ A;  1OHE A;  4BPC A;  1U26 A;  1QZ0 A;  3RGO A;  2DXP A;  4ZRT A;  2CMC A;  1PTY A;  1Q6J A;  2IMG A;  1I57 A;  4OHH A;  4RH5 A;  3ZM1 A;  2CJZ A;  4GFV A;  2CFV A;  3EB1 A;  5KAD A;  4QBW A;  1ZCK A;  3QCD A;  5KA2 A;  4GE5 A;  3V0I A;  4OHE A;  1SUG A;  4DGX A;  4NWF A;  2QBS A;  2QCT A;  5BX1 A;  5I6V A;  4WU3 A;  4KYQ A;  4RI5 A;  3ZMQ A;  2OUD A;  3AWG A;  4RH9 A;  4BJO A;  2VEX A;  3M4U A;  1YFO A;  1C86 A;  2B4O A;  4R30 A;  5KA9 A;  2VEW A;  2M3V A;  3QKQ A;  2HC1 A;  5MMZ B;  1I9S A;  1OEM X;  2BIJ A;  1YPT A;  1Q1M A;  1EEO A;  2CM8 A;  1QXK A;  5BZX A;  1M3G A;  2BV5 A;  1FPZ A;  2PA5 A;  3BLT A;  2QCJ A;  3BRH A;  2HXP A;  3O4S A;  3MOW A;  2F71 A;  2FJN A;  2QBR A;  1WCH A;  3BM8 A;  2F46 A;  3CM3 A;  2I3R A;  2B4S A;  3SME A;  2E0T A;  2CNG A;  5EHP A;  1AAX A;  3RZ2 A;  1YTS A;  1BZJ A;  3OLR A;  1OHD A;  1XM2 A;  4HJQ A;  1LQF A;  4ZN5 A;  3QCE A;  3OMH A;  1NL9 A;  3QCN A;  4ERC A;  1YZ4 A;  4Y14 A;  2FJM A;  2QDM A;  4OHL A;  3A5J A;  2H04 A;  2OZ5 A;  1C83 A;  1OEV A;  1XXP A;  2I4E A;  3PS5 A;  4WOH A;  4HJP A;  4DGP A;  1Q6P A;  1T49 A;  1Q6M A;  2AZR A;  2H02 A;  3AWE A;  2F6Z A;  1PTT A;  1YTW A;  2Y96 A;  3EU0 A;  2JJD A;  3U96 A;  5IBM A;  1A5Y A;  4B04 A;  2H4V A;  2MBC A;  2HVL A;  3F99 A;  2F6W A;  1G1F A;  1JF7 A;  1C85 A;  1RPM A;  3BLU A;  3QCF A;  3O5X A;  1OET A;  3GXG A;  1ECV A;  4QAP A;  1C84 A;  3LJ8 A;  2CMA A;  3D1H A;  2PI7 A;  3QCB A;  1YGU A;  3H2X A;  3S3E A;  2NTA A;  3QCH A;  2HB1 A;  2BGD A;  3V0E A;  2ZMM A;  2RF6 A;  3I36 A;  4KYR A;  1T4J A;  5KA4 A;  2Y2F A;  3D9C A;  1PTU A;  3AWF A;  1PH0 A;  1NO6 A;  3MOZ A;  5K9W A;  4MBB A;  3A5K A;  1KAK A;  3QCJ A;  4R0S A;  4Y2E A;  2CNF A;  3ZM2 A;  2AHS A;  2I75 A;  3I7Z A;  5HDE A;  4RDD A;  4QUN A;  1KAV A;  2CM3 A;  5KA7 A;  5KA3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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