2F6VA

Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 109
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2f6vA00
1LARA 1QZ0A 2I6PA 3RGQA 4RI5A 1PA1A 2I42A 1C87A 3MOWA 2HB1A 4QAHA 4AZ1A 4OHHA 4ZRTA 2WGPA 1ZC0A 5KADA 3RZ2A 4R30A 2B4UA 2I6JA 2B3OA 3OLRA 2AHSA 5BZZA 4KYQA 3QCFA 4WU2A 1NO6A 1X24A 4RI4A 2NLKA 1BZJA 3AWEA 2HY3A 1NNYA 2J17A 5K25A 4D3RA 2H04A 2QDPA 3S4EA 2FJNA 4J51A 1L8GA 2CNGA 2OZ5A 4WOHA 3LJ8A 2HC1A 3M4UA 4NNDA 2B07A 3QCMA 2NV5A 1P15A 1XM2A 1XRIA 2BV5A 2C7SA 3S4OA 2NT7A 2H4KA 2J16B 3OMHA 1OHDA 4OHIA 1SUGA 2F6ZA 2OC3A 5BUGA 2VEYA 5BZXA 1BZHA 5KABA 1PH0A 3EU0A 1L8KA 3A5KA 3MOZA 1PYNA 3GXGA 2E0TA 1OEOX 2BGEA 2Y96A 2Q47A 5BX1A 5IBMA 4ERCA 2HXPA 2RF6A 3QCKA 2NTAA 1NWEA 1PXHA 1U25A 2F6YA 1YGUA 1FPZA 2DXPA 2VEVA 1XBOA 2I6MA 1ZCLA 2F70A 1BZCA 2I6IA 2A3KA 4NWGA 1J4XA 3ZMQA 2CFVA 2HC2A 2R0BA 4DGXA 2AZRA 2B49A 3ZM0A 5K24A 1M3GA 3CWEA 1ZZWA 1PTYA 1EEOA 2FJMA 3D1HA 2PI7A 3I7ZA 3QCBA 3B7OA 2CM3A 1V3AA 4H34A 5I6VA 5KA8A 4JNBA 4KYRA 2BIJA 2I75A 2I6OA 1ECVA 5K22A 2PQ5A 5KA3A 2QEPA 3ZM1A 3V0FA 3V0HA 3I80A 4TVVA 2M3VA 3BRHA 3QCIA 2P6XA 2HNPA 3D1QA 4YR8B 5KACA 2ZMMA 2BGDA 4H1OA 3F99A 1G4US 1WAXA 4JMJA 1LYVA 1YGRA 4PYHA 3SR9A 2F6TA 5K9WA 1AAXA 1OEMX 5KA0A 4GE2A 2FH7A 1G7FA 4ICZA 4IKCA 2YDUA 2PBNA 1RPMA 1PTVA 2NT2A 1T4JA 2OUDA 3D1OA 2G59A 1G1HA 2F6FA 4ZN5A 5K9VA 1D5RA 1Q6SA 1GFYA 1R6HA 3F81A 3QKPA 5EHRA 3MMJA 4KI9A 3V0EA 3F9BA 3ZM3A 4GWFA 1ONZA 2ESBA 3V0JA 1KAKA 4WU3A 3NMEA 1PTTA 4PVGA 3H2XA 4D3PA 2PSZA 4OHDA 1Q6TA 1Q6JA 3U96A 3QCHA 2QCTA 1OETA 1T49A 1WRMA 2GWOA 3D9CA 3S3KA 3QCEA 4QAPA 1OEVA 2G6ZA 3SMEA 4OHLA 4OHEA 1OHCA 4HJPA 3CM3A 1YZ4A 4MBBA 2BZLA 5KAAA 2QDCA 2VEXA 2P4DA 2QBPA 2HNQA 4R0TA 2SHPA 3O4UA 2Y2FA 2I4EA 2B4OA 4I8NA 4Z6BA 1G1GA 2I1YA 2A8BA 2J16A 3O4TA 1NL9A 3ZM2A 1LQFA 1WCHA 4RDDA 1RXDA 2VEWA 3ZMPA 4GRZA 5HDEA 1YPTA 1YWFA 3PS5A 1GWZA 1PTUA 3F41A 4QBEA 2F6VA 3AWGA 4QUNA 2CM2A 3ZV2A 4GE6A 2I5XA 3QCGA 3V0GA 1I9TA 1YN9A 2H4GA 2H4VA 4B04A 2QBSA 4GFVA 3O5XA 2CMCA 2CMBA 3V0IA 4Y14A 1C84A 1EENA 3O4SA 1XXVA 4HJQA 1U26A 2H03A 1ONYA 3EMUA 1FPRA 1Q6NA 5J8RA 1C88A 3S3FA 2F6WA 1I57A 2QBQA 3I36A 3O3LA 4RH5A 3N0AA 4HRFA 5MMZB 1C86A 3BLUA 3QCLA 3F9AA 1G7GA 4R0SA 4NX8A 2ZN7A 4RH9A 2GJTA 1G4WR 4GRYA 4GE5A 1I9SA 4RHGA 1NWLA 5KA1A 2CNIA 3QCCA 2CMAA 4GS0A 4GFUA 3RO1A 2MBCA 2CM7A 1A5YA 1JF7A 4QUMA 1VHRA 1QXKA 2QDMA 2CNFA 2I3RA 1U24A 2CNEA 4DGPA 5KA4A 1YTWA 1C85A 2IMGA 1OHEA 4BPCA 1YTNA 3QCNA 1OESA 5LXQB 1PA9A 2I4GA 2JJDA 2B4SA 1XXPA 2QBRA 2I4HA 2OOQA 1T48A 2HCMA 2NZ6A 3GXHA 3S3EA 3A5JA 1G1FA 2C46A 4YAAA 2GP0A 5AWXA 4NYHA 2QCJA 1KAVA 3QKQA 3QCDA 5K23A 2F46A 3S3HA 3QCJA 2H02A 2CJZA 4RKKA 2PA5A 2I3UA 4NWFA 3D44A 4S0GA 3V0DA 2PT0A 1YFOA 1YTSA 3BLTA 4D3QA 4WTYA 2Q05A 4QBWA 4JBCA 5EHPA 1JLNA 1Q6PA 1MKPA 4Y2EA 5IBSA 4JMKA 3AWFA 1C83A 1FQ1A 2CNHA 5KA9A 4BJOA 5M43A 2F71A 3BM8A 3RGOA 1OEUA 2VEUA 1ZCKA 3D42A 2CM8A 1NZ7A 1Q6MA 2HVLA 2B4PA 3EAXA 3EZZA 1Q1MA 5KA2A 5GTJA 3EB1A 4ZI4A 5KA7A
chains in the Genus database with same CATH superfamily
1O5ZA 3HN7A 1LARA 1QZ0A 2UUOA 2I6PA 3RGQA 4RI5A 1PA1A 2I42A 1C87A 3MOWA 2HB1A 4QAHA 4AZ1A 4OHHA 2VOSA 4ZRTA 2WGPA 1ZC0A 4HV4A 3N2AA 5KADA 3RZ2A 4R30A 2B4UA 2I6JA 2B3OA 3OLRA 2AHSA 5BZZA 4KYQA 3QCFA 4WU2A 1NO6A 1X24A 4RI4A 2NLKA 2XPCA 1BZJA 3AWEA 2HY3A 1NNYA 2J17A 5K25A 4D3RA 2H04A 2QDPA 3S4EA 2FJNA 4J51A 1L8GA 2CNGA 2OZ5A 2GCBA 4WOHA 3LJ8A 2HC1A 3M4UA 4NNDA 2B07A 3QCMA 2NV5A 1P15A 2GC5A 1XM2A 1XRIA 2BV5A 2C7SA 3S4OA 2Y66A 2NT7A 2H4KA 2J16B 3OMHA 1OHDA 4OHIA 3NRSA 1SUGA 2F6ZA 2OC3A 5BUGA 2VEYA 5BZXA 1BZHA 5KABA 1FGSA 1PH0A 3EU0A 1L8KA 3A5KA 3MOZA 1PYNA 3GXGA 2E0TA 1OEOX 2BGEA 2Y96A 2Q47A 5BX1A 5IBMA 4ERCA 2HXPA 2RF6A 3QCKA 2NTAA 1NWEA 1PXHA 1U25A 2F6YA 4UAGA 1YGUA 1FPZA 2DXPA 2VEVA 1XBOA 2I6MA 1ZCLA 2F70A 1BZCA 2I6IA 2A3KA 4NWGA 1J4XA 3ZMQA 3ZM5A 2CFVA 2HC2A 2R0BA 4DGXA 4C12A 2AZRA 2Y67A 2B49A 3ZM0A 5K24A 1M3GA 3CWEA 1ZZWA 1PTYA 2UUPA 1EEOA 2UAGA 2FJMA 3D1HA 2PI7A 3I7ZA 3QCBA 3B7OA 4CVLA 2CM3A 1V3AA 4H34A 5I6VA 5KA8A 4JNBA 4KYRA 2BIJA 2JFHA 2I75A 2I6OA 2WTZA 1ECVA 5K22A 2PQ5A 5KA3A 2QEPA 3ZM1A 3V0FA 3V0HA 3I80A 4TVVA 2M3VA 2F00A 3BRHA 3QCIA 2P6XA 4QF5A 1W78A 2HNPA 3D1QA 4YR8B 5KACA 2ZMMA 2BGDA 4H1OA 3F99A 1G4US 1WAXA 4JMJA 1LYVA 4CVKA 1YGRA 4PYHA 3SR9A 5A5EA 4QDIA 2GCAA 2F6TA 5K9WA 1AAXA 1OEMX 5KA0A 4GE2A 2FH7A 1G7FA 4ICZA 3QCZA 3ZL8A 4IKCA 2YDUA 2PBNA 1RPMA 1PTVA 2NT2A 2VTEA 1GG4A 1T4JA 2OUDA 3D1OA 2G59A 1J6UA 1G1HA 2F6FA 2JFFA 1EEHA 4ZN5A 2XJAA 5K9VA 1D5RA 1Q6SA 1GFYA 1R6HA 3F81A 3QKPA 5EHRA 3MMJA 4KI9A 3V0EA 3F9BA 3ZM3A 4GWFA 1ONZA 2ESBA 3V0JA 1KAKA 4WU3A 3NMEA 1PTTA 4PVGA 3H2XA 4D3PA 3UAGA 2PSZA 3PYZA 4OHDA 1Q6TA 1Q6JA 3U96A 3QCHA 2QCTA 1OETA 5A5FA 1T49A 1WRMA 2GWOA 3D9CA 3S3KA 3QCEA 4QAPA 1OEVA 2G6ZA 3SMEA 4OHLA 4OHEA 1OHCA 4HJPA 3CM3A 1YZ4A 4MBBA 2BZLA 5KAAA 2QDCA 2VEXA 2P4DA 2QBPA 2HNQA 4R0TA 2SHPA 1P3DA 3O4UA 2Y2FA 2I4EA 2B4OA 4I8NA 4Z6BA 1G1GA 2I1YA 2A8BA 2J16A 3O4TA 1NL9A 3ZM2A 1LQFA 1WCHA 4RDDA 1RXDA 4BUCA 1GQYA 2VEWA 3ZMPA 4GRZA 5HDEA 1YPTA 1YWFA 3PS5A 1GWZA 1PTUA 2VTDA 3F41A 4QBEA 2F6VA 3AWGA 4QUNA 2CM2A 3ZV2A 4GE6A 2I5XA 3QCGA 3V0GA 1I9TA 1YN9A 2H4GA 2H4VA 4B04A 1P31A 2QBSA 4GFVA 3O5XA 2CMCA 2CMBA 3V0IA 4Y14A 1C84A 1EENA 2AM2A 3O4SA 1XXVA 1E8CA 3MVNA 4HJQA 1U26A 2H03A 1ONYA 3EMUA 1FPRA 1Q6NA 5J8RA 1C88A 2X5OA 4C13A 3S3FA 2F6WA 1I57A 2QBQA 3I36A 3O3LA 4RH5A 3N0AA 4HRFA 5MMZB 1C86A 1W7KA 3BLUA 3QCLA 3F9AA 1G7GA 4R0SA 4NX8A 2ZN7A 4RH9A 2GJTA 1G4WR 4GRYA 2AM1A 3ZM6A 4GE5A 1I9SA 4BUBA 4RHGA 1NWLA 3LK7A 5KA1A 2CNIA 3QCCA 2CMAA 4GS0A 4GFUA 3RO1A 2MBCA 2CM7A 1A5YA 1JF7A 4QUMA 1VHRA 1QXKA 2QDMA 2CNFA 2I3RA 1U24A 2CNEA 4DGPA 5KA4A 1UAGA 1YTWA 1C85A 2IMGA 1OHEA 4ZIYA 4BPCA 1YTNA 3QCNA 1OESA 5LXQB 1PA9A 2I4GA 2JJDA 2B4SA 1GQQA 1XXPA 2QBRA 1JBWA 2I4HA 2Y68A 2OOQA 1T48A 2HCMA 2NZ6A 1JBVA 3GXHA 3S3EA 2VORA 3A5JA 1G1FA 2C46A 4YAAA 2GP0A 5AWXA 4NYHA 2QCJA 1KAVA 3QKQA 3QCDA 5K23A 2F46A 3S3HA 4CVMA 2WJPA 3QCJA 2H02A 2CJZA 4RKKA 2PA5A 2I3UA 4NWFA 3D44A 4S0GA 3V0DA 2PT0A 1YFOA 1YTSA 3BLTA 4D3QA 4WTYA 2Q05A 4QBWA 4JBCA 5EHPA 1JLNA 1Q6PA 1MKPA 4Y2EA 5IBSA 4JMKA 3AWFA 1E0DA 2GC6A 1C83A 1FQ1A 2CNHA 5KA9A 4BJOA 5M43A 2F71A 3BM8A 3RGOA 1OEUA 2VEUA 1ZCKA 3D42A 2Y1OA 2CM8A 1NZ7A 1Q6MA 2HVLA 2B4PA 3EAXA 3EZZA 1Q1MA 5KA2A 5GTJA 3EB1A 2JFGA 4ZI4A 5KA7A
chains in the Genus database with same CATH topology
1LARA 1QZ0A 2I6PA 3RGQA 4RI5A 1PA1A 2I42A 1C87A 3MOWA 2HB1A 4QAHA 4AZ1A 4OHHA 4ZRTA 2WGPA 1ZC0A 5KADA 3RZ2A 4R30A 2B4UA 2I6JA 2B3OA 3OLRA 2AHSA 5BZZA 4KYQA 3QCFA 4WU2A 1NO6A 1X24A 4RI4A 2NLKA 1BZJA 3AWEA 2HY3A 1NNYA 2J17A 5K25A 4D3RA 2H04A 2QDPA 3S4EA 2FJNA 4J51A 1L8GA 2CNGA 2OZ5A 4WOHA 3LJ8A 2HC1A 3M4UA 4NNDA 2B07A 3QCMA 2NV5A 1P15A 1XM2A 1XRIA 2BV5A 2C7SA 3S4OA 2NT7A 2H4KA 2J16B 3OMHA 1OHDA 4OHIA 1SUGA 2F6ZA 2OC3A 5BUGA 2VEYA 5BZXA 1BZHA 5KABA 1PH0A 3EU0A 1L8KA 3A5KA 3MOZA 1PYNA 3GXGA 2E0TA 1OEOX 2BGEA 2Y96A 2Q47A 5BX1A 5IBMA 4ERCA 2HXPA 2RF6A 3QCKA 2NTAA 1NWEA 1PXHA 1U25A 2F6YA 1YGUA 1FPZA 2DXPA 2VEVA 1XBOA 2I6MA 1ZCLA 2F70A 1BZCA 2I6IA 2A3KA 4NWGA 1J4XA 3ZMQA 2CFVA 2HC2A 2R0BA 4DGXA 2AZRA 2B49A 3ZM0A 5K24A 1M3GA 3CWEA 1ZZWA 1PTYA 1EEOA 2FJMA 3D1HA 2PI7A 3I7ZA 3QCBA 3B7OA 2CM3A 1V3AA 4H34A 5I6VA 5KA8A 4JNBA 4KYRA 2BIJA 2I75A 2I6OA 1ECVA 5K22A 2PQ5A 5KA3A 2QEPA 3ZM1A 3V0FA 3V0HA 3I80A 4TVVA 2M3VA 3BRHA 3QCIA 2P6XA 2HNPA 3D1QA 4YR8B 5KACA 2ZMMA 2BGDA 4H1OA 3F99A 1G4US 1WAXA 4JMJA 1LYVA 1YGRA 4PYHA 3SR9A 2F6TA 5K9WA 1AAXA 1OEMX 5KA0A 4GE2A 2FH7A 1G7FA 4ICZA 4IKCA 2YDUA 2PBNA 1RPMA 1PTVA 2NT2A 1T4JA 2OUDA 3D1OA 2G59A 1G1HA 2F6FA 4ZN5A 5K9VA 1D5RA 1Q6SA 1GFYA 1R6HA 3F81A 3QKPA 5EHRA 3MMJA 4KI9A 3V0EA 3F9BA 3ZM3A 4GWFA 1ONZA 2ESBA 3V0JA 1KAKA 4WU3A 3NMEA 1PTTA 4PVGA 3H2XA 4D3PA 2PSZA 4OHDA 1Q6TA 1Q6JA 3U96A 3QCHA 2QCTA 1OETA 1T49A 1WRMA 2GWOA 3D9CA 3S3KA 3QCEA 4QAPA 1OEVA 2G6ZA 3SMEA 4OHLA 4OHEA 1OHCA 4HJPA 3CM3A 1YZ4A 4MBBA 2BZLA 5KAAA 2QDCA 2VEXA 2P4DA 2QBPA 2HNQA 4R0TA 2SHPA 3O4UA 2Y2FA 2I4EA 2B4OA 4I8NA 4Z6BA 1G1GA 2I1YA 2A8BA 2J16A 3O4TA 1NL9A 3ZM2A 1LQFA 1WCHA 4RDDA 1RXDA 2VEWA 3ZMPA 4GRZA 5HDEA 1YPTA 1YWFA 3PS5A 1GWZA 1PTUA 3F41A 4QBEA 2F6VA 3AWGA 4QUNA 2CM2A 3ZV2A 4GE6A 2I5XA 3QCGA 3V0GA 1I9TA 1YN9A 2H4GA 2H4VA 4B04A 2QBSA 4GFVA 3O5XA 2CMCA 2CMBA 3V0IA 4Y14A 1C84A 1EENA 3O4SA 1XXVA 4HJQA 1U26A 2H03A 1ONYA 3EMUA 1FPRA 1Q6NA 5J8RA 1C88A 3S3FA 2F6WA 1I57A 2QBQA 3I36A 3O3LA 4RH5A 3N0AA 4HRFA 5MMZB 1C86A 3BLUA 3QCLA 3F9AA 1G7GA 4R0SA 4NX8A 2ZN7A 4RH9A 2GJTA 1G4WR 4GRYA 4GE5A 1I9SA 4RHGA 1NWLA 5KA1A 2CNIA 3QCCA 2CMAA 4GS0A 4GFUA 3RO1A 2MBCA 2CM7A 1A5YA 1JF7A 4QUMA 1VHRA 1QXKA 2QDMA 2CNFA 2I3RA 1U24A 2CNEA 4DGPA 5KA4A 1YTWA 1C85A 2IMGA 1OHEA 4BPCA 1YTNA 3QCNA 1OESA 5LXQB 1PA9A 2I4GA 2JJDA 2B4SA 1XXPA 2QBRA 2I4HA 2OOQA 1T48A 2HCMA 2NZ6A 3GXHA 3S3EA 3A5JA 1G1FA 2C46A 4YAAA 2GP0A 5AWXA 4NYHA 2QCJA 1KAVA 3QKQA 3QCDA 5K23A 2F46A 3S3HA 3QCJA 2H02A 2CJZA 4RKKA 2PA5A 2I3UA 4NWFA 3D44A 4S0GA 3V0DA 2PT0A 1YFOA 1YTSA 3BLTA 4D3QA 4WTYA 2Q05A 4QBWA 4JBCA 5EHPA 1JLNA 1Q6PA 1MKPA 4Y2EA 5IBSA 4JMKA 3AWFA 1C83A 1FQ1A 2CNHA 5KA9A 4BJOA 5M43A 2F71A 3BM8A 3RGOA 1OEUA 2VEUA 1ZCKA 3D42A 2CM8A 1NZ7A 1Q6MA 2HVLA 2B4PA 3EAXA 3EZZA 1Q1MA 5KA2A 5GTJA 3EB1A 4ZI4A 5KA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LAR A;  1QZ0 A;  2I6P A;  3RGQ A;  4RI5 A;  1PA1 A;  2I42 A;  1C87 A;  3MOW A;  2HB1 A;  4QAH A;  4AZ1 A;  4OHH A;  4ZRT A;  2WGP A;  1ZC0 A;  5KAD A;  3RZ2 A;  4R30 A;  2B4U A;  2I6J A;  2B3O A;  3OLR A;  2AHS A;  5BZZ A;  4KYQ A;  3QCF A;  4WU2 A;  1NO6 A;  1X24 A;  4RI4 A;  2NLK A;  1BZJ A;  3AWE A;  2HY3 A;  1NNY A;  2J17 A;  5K25 A;  4D3R A;  2H04 A;  2QDP A;  3S4E A;  2FJN A;  4J51 A;  1L8G A;  2CNG A;  2OZ5 A;  4WOH A;  3LJ8 A;  2HC1 A;  3M4U A;  4NND A;  2B07 A;  3QCM A;  2NV5 A;  1P15 A;  1XM2 A;  1XRI A;  2BV5 A;  2C7S A;  3S4O A;  2NT7 A;  2H4K A;  2J16 B;  3OMH A;  1OHD A;  4OHI A;  1SUG A;  2F6Z A;  2OC3 A;  5BUG A;  2VEY A;  5BZX A;  1BZH A;  5KAB A;  1PH0 A;  3EU0 A;  1L8K A;  3A5K A;  3MOZ A;  1PYN A;  3GXG A;  2E0T A;  1OEO X;  2BGE A;  2Y96 A;  2Q47 A;  5BX1 A;  5IBM A;  4ERC A;  2HXP A;  2RF6 A;  3QCK A;  2NTA A;  1NWE A;  1PXH A;  1U25 A;  2F6Y A;  1YGU A;  1FPZ A;  2DXP A;  2VEV A;  1XBO A;  2I6M A;  1ZCL A;  2F70 A;  1BZC A;  2I6I A;  2A3K A;  4NWG A;  1J4X A;  3ZMQ A;  2CFV A;  2HC2 A;  2R0B A;  4DGX A;  2AZR A;  2B49 A;  3ZM0 A;  5K24 A;  1M3G A;  3CWE A;  1ZZW A;  1PTY A;  1EEO A;  2FJM A;  3D1H A;  2PI7 A;  3I7Z A;  3QCB A;  3B7O A;  2CM3 A;  1V3A A;  4H34 A;  5I6V A;  5KA8 A;  4JNB A;  4KYR A;  2BIJ A;  2I75 A;  2I6O A;  1ECV A;  5K22 A;  2PQ5 A;  5KA3 A;  2QEP A;  3ZM1 A;  3V0F A;  3V0H A;  3I80 A;  4TVV A;  2M3V A;  3BRH A;  3QCI A;  2P6X A;  2HNP A;  3D1Q A;  4YR8 B;  5KAC A;  2ZMM A;  2BGD A;  4H1O A;  3F99 A;  1G4U S;  1WAX A;  4JMJ A;  1LYV A;  1YGR A;  4PYH A;  3SR9 A;  2F6T A;  5K9W A;  1AAX A;  1OEM X;  5KA0 A;  4GE2 A;  2FH7 A;  1G7F A;  4ICZ A;  4IKC A;  2YDU A;  2PBN A;  1RPM A;  1PTV A;  2NT2 A;  1T4J A;  2OUD A;  3D1O A;  2G59 A;  1G1H A;  2F6F A;  4ZN5 A;  5K9V A;  1D5R A;  1Q6S A;  1GFY A;  1R6H A;  3F81 A;  3QKP A;  5EHR A;  3MMJ A;  4KI9 A;  3V0E A;  3F9B A;  3ZM3 A;  4GWF A;  1ONZ A;  2ESB A;  3V0J A;  1KAK A;  4WU3 A;  3NME A;  1PTT A;  4PVG A;  3H2X A;  4D3P A;  2PSZ A;  4OHD A;  1Q6T A;  1Q6J A;  3U96 A;  3QCH A;  2QCT A;  1OET A;  1T49 A;  1WRM A;  2GWO A;  3D9C A;  3S3K A;  3QCE A;  4QAP A;  1OEV A;  2G6Z A;  3SME A;  4OHL A;  4OHE A;  1OHC A;  4HJP A;  3CM3 A;  1YZ4 A;  4MBB A;  2BZL A;  5KAA A;  2QDC A;  2VEX A;  2P4D A;  2QBP A;  2HNQ A;  4R0T A;  2SHP A;  3O4U A;  2Y2F A;  2I4E A;  2B4O A;  4I8N A;  4Z6B A;  1G1G A;  2I1Y A;  2A8B A;  2J16 A;  3O4T A;  1NL9 A;  3ZM2 A;  1LQF A;  1WCH A;  4RDD A;  1RXD A;  2VEW A;  3ZMP A;  4GRZ A;  5HDE A;  1YPT A;  1YWF A;  3PS5 A;  1GWZ A;  1PTU A;  3F41 A;  4QBE A;  2F6V A;  3AWG A;  4QUN A;  2CM2 A;  3ZV2 A;  4GE6 A;  2I5X A;  3QCG A;  3V0G A;  1I9T A;  1YN9 A;  2H4G A;  2H4V A;  4B04 A;  2QBS A;  4GFV A;  3O5X A;  2CMC A;  2CMB A;  3V0I A;  4Y14 A;  1C84 A;  1EEN A;  3O4S A;  1XXV A;  4HJQ A;  1U26 A;  2H03 A;  1ONY A;  3EMU A;  1FPR A;  1Q6N A;  5J8R A;  1C88 A;  3S3F A;  2F6W A;  1I57 A;  2QBQ A;  3I36 A;  3O3L A;  4RH5 A;  3N0A A;  4HRF A;  5MMZ B;  1C86 A;  3BLU A;  3QCL A;  3F9A A;  1G7G A;  4R0S A;  4NX8 A;  2ZN7 A;  4RH9 A;  2GJT A;  1G4W R;  4GRY A;  4GE5 A;  1I9S A;  4RHG A;  1NWL A;  5KA1 A;  2CNI A;  3QCC A;  2CMA A;  4GS0 A;  4GFU A;  3RO1 A;  2MBC A;  2CM7 A;  1A5Y A;  1JF7 A;  4QUM A;  1VHR A;  1QXK A;  2QDM A;  2CNF A;  2I3R A;  1U24 A;  2CNE A;  4DGP A;  5KA4 A;  1YTW A;  1C85 A;  2IMG A;  1OHE A;  4BPC A;  1YTN A;  3QCN A;  1OES A;  5LXQ B;  1PA9 A;  2I4G A;  2JJD A;  2B4S A;  1XXP A;  2QBR A;  2I4H A;  2OOQ A;  1T48 A;  2HCM A;  2NZ6 A;  3GXH A;  3S3E A;  3A5J A;  1G1F A;  2C46 A;  4YAA A;  2GP0 A;  5AWX A;  4NYH A;  2QCJ A;  1KAV A;  3QKQ A;  3QCD A;  5K23 A;  2F46 A;  3S3H A;  3QCJ A;  2H02 A;  2CJZ A;  4RKK A;  2PA5 A;  2I3U A;  4NWF A;  3D44 A;  4S0G A;  3V0D A;  2PT0 A;  1YFO A;  1YTS A;  3BLT A;  4D3Q A;  4WTY A;  2Q05 A;  4QBW A;  4JBC A;  5EHP A;  1JLN A;  1Q6P A;  1MKP A;  4Y2E A;  5IBS A;  4JMK A;  3AWF A;  1C83 A;  1FQ1 A;  2CNH A;  5KA9 A;  4BJO A;  5M43 A;  2F71 A;  3BM8 A;  3RGO A;  1OEU A;  2VEU A;  1ZCK A;  3D42 A;  2CM8 A;  1NZ7 A;  1Q6M A;  2HVL A;  2B4P A;  3EAX A;  3EZZ A;  1Q1M A;  5KA2 A;  5GTJ A;  3EB1 A;  4ZI4 A;  5KA7 A; 
#chains in the Genus database with same CATH topology
 1O5Z A;  3HN7 A;  1LAR A;  1QZ0 A;  2UUO A;  2I6P A;  3RGQ A;  4RI5 A;  1PA1 A;  2I42 A;  1C87 A;  3MOW A;  2HB1 A;  4QAH A;  4AZ1 A;  4OHH A;  2VOS A;  4ZRT A;  2WGP A;  1ZC0 A;  4HV4 A;  3N2A A;  5KAD A;  3RZ2 A;  4R30 A;  2B4U A;  2I6J A;  2B3O A;  3OLR A;  2AHS A;  5BZZ A;  4KYQ A;  3QCF A;  4WU2 A;  1NO6 A;  1X24 A;  4RI4 A;  2NLK A;  2XPC A;  1BZJ A;  3AWE A;  2HY3 A;  1NNY A;  2J17 A;  5K25 A;  4D3R A;  2H04 A;  2QDP A;  3S4E A;  2FJN A;  4J51 A;  1L8G A;  2CNG A;  2OZ5 A;  2GCB A;  4WOH A;  3LJ8 A;  2HC1 A;  3M4U A;  4NND A;  2B07 A;  3QCM A;  2NV5 A;  1P15 A;  2GC5 A;  1XM2 A;  1XRI A;  2BV5 A;  2C7S A;  3S4O A;  2Y66 A;  2NT7 A;  2H4K A;  2J16 B;  3OMH A;  1OHD A;  4OHI A;  3NRS A;  1SUG A;  2F6Z A;  2OC3 A;  5BUG A;  2VEY A;  5BZX A;  1BZH A;  5KAB A;  1FGS A;  1PH0 A;  3EU0 A;  1L8K A;  3A5K A;  3MOZ A;  1PYN A;  3GXG A;  2E0T A;  1OEO X;  2BGE A;  2Y96 A;  2Q47 A;  5BX1 A;  5IBM A;  4ERC A;  2HXP A;  2RF6 A;  3QCK A;  2NTA A;  1NWE A;  1PXH A;  1U25 A;  2F6Y A;  4UAG A;  1YGU A;  1FPZ A;  2DXP A;  2VEV A;  1XBO A;  2I6M A;  1ZCL A;  2F70 A;  1BZC A;  2I6I A;  2A3K A;  4NWG A;  1J4X A;  3ZMQ A;  3ZM5 A;  2CFV A;  2HC2 A;  2R0B A;  4DGX A;  4C12 A;  2AZR A;  2Y67 A;  2B49 A;  3ZM0 A;  5K24 A;  1M3G A;  3CWE A;  1ZZW A;  1PTY A;  2UUP A;  1EEO A;  2UAG A;  2FJM A;  3D1H A;  2PI7 A;  3I7Z A;  3QCB A;  3B7O A;  4CVL A;  2CM3 A;  1V3A A;  4H34 A;  5I6V A;  5KA8 A;  4JNB A;  4KYR A;  2BIJ A;  2JFH A;  2I75 A;  2I6O A;  2WTZ A;  1ECV A;  5K22 A;  2PQ5 A;  5KA3 A;  2QEP A;  3ZM1 A;  3V0F A;  3V0H A;  3I80 A;  4TVV A;  2M3V A;  2F00 A;  3BRH A;  3QCI A;  2P6X A;  4QF5 A;  1W78 A;  2HNP A;  3D1Q A;  4YR8 B;  5KAC A;  2ZMM A;  2BGD A;  4H1O A;  3F99 A;  1G4U S;  1WAX A;  4JMJ A;  1LYV A;  4CVK A;  1YGR A;  4PYH A;  3SR9 A;  5A5E A;  4QDI A;  2GCA A;  2F6T A;  5K9W A;  1AAX A;  1OEM X;  5KA0 A;  4GE2 A;  2FH7 A;  1G7F A;  4ICZ A;  3QCZ A;  3ZL8 A;  4IKC A;  2YDU A;  2PBN A;  1RPM A;  1PTV A;  2NT2 A;  2VTE A;  1GG4 A;  1T4J A;  2OUD A;  3D1O A;  2G59 A;  1J6U A;  1G1H A;  2F6F A;  2JFF A;  1EEH A;  4ZN5 A;  2XJA A;  5K9V A;  1D5R A;  1Q6S A;  1GFY A;  1R6H A;  3F81 A;  3QKP A;  5EHR A;  3MMJ A;  4KI9 A;  3V0E A;  3F9B A;  3ZM3 A;  4GWF A;  1ONZ A;  2ESB A;  3V0J A;  1KAK A;  4WU3 A;  3NME A;  1PTT A;  4PVG A;  3H2X A;  4D3P A;  3UAG A;  2PSZ A;  3PYZ A;  4OHD A;  1Q6T A;  1Q6J A;  3U96 A;  3QCH A;  2QCT A;  1OET A;  5A5F A;  1T49 A;  1WRM A;  2GWO A;  3D9C A;  3S3K A;  3QCE A;  4QAP A;  1OEV A;  2G6Z A;  3SME A;  4OHL A;  4OHE A;  1OHC A;  4HJP A;  3CM3 A;  1YZ4 A;  4MBB A;  2BZL A;  5KAA A;  2QDC A;  2VEX A;  2P4D A;  2QBP A;  2HNQ A;  4R0T A;  2SHP A;  1P3D A;  3O4U A;  2Y2F A;  2I4E A;  2B4O A;  4I8N A;  4Z6B A;  1G1G A;  2I1Y A;  2A8B A;  2J16 A;  3O4T A;  1NL9 A;  3ZM2 A;  1LQF A;  1WCH A;  4RDD A;  1RXD A;  4BUC A;  1GQY A;  2VEW A;  3ZMP A;  4GRZ A;  5HDE A;  1YPT A;  1YWF A;  3PS5 A;  1GWZ A;  1PTU A;  2VTD A;  3F41 A;  4QBE A;  2F6V A;  3AWG A;  4QUN A;  2CM2 A;  3ZV2 A;  4GE6 A;  2I5X A;  3QCG A;  3V0G A;  1I9T A;  1YN9 A;  2H4G A;  2H4V A;  4B04 A;  1P31 A;  2QBS A;  4GFV A;  3O5X A;  2CMC A;  2CMB A;  3V0I A;  4Y14 A;  1C84 A;  1EEN A;  2AM2 A;  3O4S A;  1XXV A;  1E8C A;  3MVN A;  4HJQ A;  1U26 A;  2H03 A;  1ONY A;  3EMU A;  1FPR A;  1Q6N A;  5J8R A;  1C88 A;  2X5O A;  4C13 A;  3S3F A;  2F6W A;  1I57 A;  2QBQ A;  3I36 A;  3O3L A;  4RH5 A;  3N0A A;  4HRF A;  5MMZ B;  1C86 A;  1W7K A;  3BLU A;  3QCL A;  3F9A A;  1G7G A;  4R0S A;  4NX8 A;  2ZN7 A;  4RH9 A;  2GJT A;  1G4W R;  4GRY A;  2AM1 A;  3ZM6 A;  4GE5 A;  1I9S A;  4BUB A;  4RHG A;  1NWL A;  3LK7 A;  5KA1 A;  2CNI A;  3QCC A;  2CMA A;  4GS0 A;  4GFU A;  3RO1 A;  2MBC A;  2CM7 A;  1A5Y A;  1JF7 A;  4QUM A;  1VHR A;  1QXK A;  2QDM A;  2CNF A;  2I3R A;  1U24 A;  2CNE A;  4DGP A;  5KA4 A;  1UAG A;  1YTW A;  1C85 A;  2IMG A;  1OHE A;  4ZIY A;  4BPC A;  1YTN A;  3QCN A;  1OES A;  5LXQ B;  1PA9 A;  2I4G A;  2JJD A;  2B4S A;  1GQQ A;  1XXP A;  2QBR A;  1JBW A;  2I4H A;  2Y68 A;  2OOQ A;  1T48 A;  2HCM A;  2NZ6 A;  1JBV A;  3GXH A;  3S3E A;  2VOR A;  3A5J A;  1G1F A;  2C46 A;  4YAA A;  2GP0 A;  5AWX A;  4NYH A;  2QCJ A;  1KAV A;  3QKQ A;  3QCD A;  5K23 A;  2F46 A;  3S3H A;  4CVM A;  2WJP A;  3QCJ A;  2H02 A;  2CJZ A;  4RKK A;  2PA5 A;  2I3U A;  4NWF A;  3D44 A;  4S0G A;  3V0D A;  2PT0 A;  1YFO A;  1YTS A;  3BLT A;  4D3Q A;  4WTY A;  2Q05 A;  4QBW A;  4JBC A;  5EHP A;  1JLN A;  1Q6P A;  1MKP A;  4Y2E A;  5IBS A;  4JMK A;  3AWF A;  1E0D A;  2GC6 A;  1C83 A;  1FQ1 A;  2CNH A;  5KA9 A;  4BJO A;  5M43 A;  2F71 A;  3BM8 A;  3RGO A;  1OEU A;  2VEU A;  1ZCK A;  3D42 A;  2Y1O A;  2CM8 A;  1NZ7 A;  1Q6M A;  2HVL A;  2B4P A;  3EAX A;  3EZZ A;  1Q1M A;  5KA2 A;  5GTJ A;  3EB1 A;  2JFG A;  4ZI4 A;  5KA7 A; 
#chains in the Genus database with same CATH homology
 1LAR A;  1QZ0 A;  2I6P A;  3RGQ A;  4RI5 A;  1PA1 A;  2I42 A;  1C87 A;  3MOW A;  2HB1 A;  4QAH A;  4AZ1 A;  4OHH A;  4ZRT A;  2WGP A;  1ZC0 A;  5KAD A;  3RZ2 A;  4R30 A;  2B4U A;  2I6J A;  2B3O A;  3OLR A;  2AHS A;  5BZZ A;  4KYQ A;  3QCF A;  4WU2 A;  1NO6 A;  1X24 A;  4RI4 A;  2NLK A;  1BZJ A;  3AWE A;  2HY3 A;  1NNY A;  2J17 A;  5K25 A;  4D3R A;  2H04 A;  2QDP A;  3S4E A;  2FJN A;  4J51 A;  1L8G A;  2CNG A;  2OZ5 A;  4WOH A;  3LJ8 A;  2HC1 A;  3M4U A;  4NND A;  2B07 A;  3QCM A;  2NV5 A;  1P15 A;  1XM2 A;  1XRI A;  2BV5 A;  2C7S A;  3S4O A;  2NT7 A;  2H4K A;  2J16 B;  3OMH A;  1OHD A;  4OHI A;  1SUG A;  2F6Z A;  2OC3 A;  5BUG A;  2VEY A;  5BZX A;  1BZH A;  5KAB A;  1PH0 A;  3EU0 A;  1L8K A;  3A5K A;  3MOZ A;  1PYN A;  3GXG A;  2E0T A;  1OEO X;  2BGE A;  2Y96 A;  2Q47 A;  5BX1 A;  5IBM A;  4ERC A;  2HXP A;  2RF6 A;  3QCK A;  2NTA A;  1NWE A;  1PXH A;  1U25 A;  2F6Y A;  1YGU A;  1FPZ A;  2DXP A;  2VEV A;  1XBO A;  2I6M A;  1ZCL A;  2F70 A;  1BZC A;  2I6I A;  2A3K A;  4NWG A;  1J4X A;  3ZMQ A;  2CFV A;  2HC2 A;  2R0B A;  4DGX A;  2AZR A;  2B49 A;  3ZM0 A;  5K24 A;  1M3G A;  3CWE A;  1ZZW A;  1PTY A;  1EEO A;  2FJM A;  3D1H A;  2PI7 A;  3I7Z A;  3QCB A;  3B7O A;  2CM3 A;  1V3A A;  4H34 A;  5I6V A;  5KA8 A;  4JNB A;  4KYR A;  2BIJ A;  2I75 A;  2I6O A;  1ECV A;  5K22 A;  2PQ5 A;  5KA3 A;  2QEP A;  3ZM1 A;  3V0F A;  3V0H A;  3I80 A;  4TVV A;  2M3V A;  3BRH A;  3QCI A;  2P6X A;  2HNP A;  3D1Q A;  4YR8 B;  5KAC A;  2ZMM A;  2BGD A;  4H1O A;  3F99 A;  1G4U S;  1WAX A;  4JMJ A;  1LYV A;  1YGR A;  4PYH A;  3SR9 A;  2F6T A;  5K9W A;  1AAX A;  1OEM X;  5KA0 A;  4GE2 A;  2FH7 A;  1G7F A;  4ICZ A;  4IKC A;  2YDU A;  2PBN A;  1RPM A;  1PTV A;  2NT2 A;  1T4J A;  2OUD A;  3D1O A;  2G59 A;  1G1H A;  2F6F A;  4ZN5 A;  5K9V A;  1D5R A;  1Q6S A;  1GFY A;  1R6H A;  3F81 A;  3QKP A;  5EHR A;  3MMJ A;  4KI9 A;  3V0E A;  3F9B A;  3ZM3 A;  4GWF A;  1ONZ A;  2ESB A;  3V0J A;  1KAK A;  4WU3 A;  3NME A;  1PTT A;  4PVG A;  3H2X A;  4D3P A;  2PSZ A;  4OHD A;  1Q6T A;  1Q6J A;  3U96 A;  3QCH A;  2QCT A;  1OET A;  1T49 A;  1WRM A;  2GWO A;  3D9C A;  3S3K A;  3QCE A;  4QAP A;  1OEV A;  2G6Z A;  3SME A;  4OHL A;  4OHE A;  1OHC A;  4HJP A;  3CM3 A;  1YZ4 A;  4MBB A;  2BZL A;  5KAA A;  2QDC A;  2VEX A;  2P4D A;  2QBP A;  2HNQ A;  4R0T A;  2SHP A;  3O4U A;  2Y2F A;  2I4E A;  2B4O A;  4I8N A;  4Z6B A;  1G1G A;  2I1Y A;  2A8B A;  2J16 A;  3O4T A;  1NL9 A;  3ZM2 A;  1LQF A;  1WCH A;  4RDD A;  1RXD A;  2VEW A;  3ZMP A;  4GRZ A;  5HDE A;  1YPT A;  1YWF A;  3PS5 A;  1GWZ A;  1PTU A;  3F41 A;  4QBE A;  2F6V A;  3AWG A;  4QUN A;  2CM2 A;  3ZV2 A;  4GE6 A;  2I5X A;  3QCG A;  3V0G A;  1I9T A;  1YN9 A;  2H4G A;  2H4V A;  4B04 A;  2QBS A;  4GFV A;  3O5X A;  2CMC A;  2CMB A;  3V0I A;  4Y14 A;  1C84 A;  1EEN A;  3O4S A;  1XXV A;  4HJQ A;  1U26 A;  2H03 A;  1ONY A;  3EMU A;  1FPR A;  1Q6N A;  5J8R A;  1C88 A;  3S3F A;  2F6W A;  1I57 A;  2QBQ A;  3I36 A;  3O3L A;  4RH5 A;  3N0A A;  4HRF A;  5MMZ B;  1C86 A;  3BLU A;  3QCL A;  3F9A A;  1G7G A;  4R0S A;  4NX8 A;  2ZN7 A;  4RH9 A;  2GJT A;  1G4W R;  4GRY A;  4GE5 A;  1I9S A;  4RHG A;  1NWL A;  5KA1 A;  2CNI A;  3QCC A;  2CMA A;  4GS0 A;  4GFU A;  3RO1 A;  2MBC A;  2CM7 A;  1A5Y A;  1JF7 A;  4QUM A;  1VHR A;  1QXK A;  2QDM A;  2CNF A;  2I3R A;  1U24 A;  2CNE A;  4DGP A;  5KA4 A;  1YTW A;  1C85 A;  2IMG A;  1OHE A;  4BPC A;  1YTN A;  3QCN A;  1OES A;  5LXQ B;  1PA9 A;  2I4G A;  2JJD A;  2B4S A;  1XXP A;  2QBR A;  2I4H A;  2OOQ A;  1T48 A;  2HCM A;  2NZ6 A;  3GXH A;  3S3E A;  3A5J A;  1G1F A;  2C46 A;  4YAA A;  2GP0 A;  5AWX A;  4NYH A;  2QCJ A;  1KAV A;  3QKQ A;  3QCD A;  5K23 A;  2F46 A;  3S3H A;  3QCJ A;  2H02 A;  2CJZ A;  4RKK A;  2PA5 A;  2I3U A;  4NWF A;  3D44 A;  4S0G A;  3V0D A;  2PT0 A;  1YFO A;  1YTS A;  3BLT A;  4D3Q A;  4WTY A;  2Q05 A;  4QBW A;  4JBC A;  5EHP A;  1JLN A;  1Q6P A;  1MKP A;  4Y2E A;  5IBS A;  4JMK A;  3AWF A;  1C83 A;  1FQ1 A;  2CNH A;  5KA9 A;  4BJO A;  5M43 A;  2F71 A;  3BM8 A;  3RGO A;  1OEU A;  2VEU A;  1ZCK A;  3D42 A;  2CM8 A;  1NZ7 A;  1Q6M A;  2HVL A;  2B4P A;  3EAX A;  3EZZ A;  1Q1M A;  5KA2 A;  5GTJ A;  3EB1 A;  4ZI4 A;  5KA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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