2F70A

Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 108
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2f70A00
2MBCA 2J17A 3D42A 4H1OA 1I9SA 4B04A 2B4UA 3S3EA 2QBRA 4PYHA 3F41A 2I6IA 2BV5A 2CNEA 2F71A 4GE2A 1C84A 1YPTA 1NWLA 2YDUA 2PQ5A 4TVVA 1FQ1A 4GRYA 1G4WR 1R6HA 4GS0A 2NZ6A 4NWFA 4NWGA 2B49A 1JF7A 5KAAA 2P6XA 3F9BA 4PVGA 5KA8A 5KA0A 1FPRA 2F70A 3ZM0A 2B07A 4QUMA 5M43A 3V0EA 4J51A 2CM7A 2I5XA 2FJNA 5KADA 2OUDA 4R0SA 1LARA 4RKKA 1VHRA 3V0DA 2HB1A 2I1YA 5KA2A 3MMJA 3QCBA 5BUGA 1D5RA 3D44A 5KA1A 3N0AA 1XRIA 2C7SA 4QBWA 2QBPA 1I9TA 2HNPA 3D1OA 2PA5A 1LYVA 1U26A 3QCDA 3QCHA 2F6VA 5IBMA 2GWOA 3V0IA 2H04A 1Q6PA 4HJQA 2Q05A 1GWZA 5KA4A 1PYNA 1YGUA 2C46A 1OEMX 2CNFA 3OMHA 2QEPA 1FPZA 1OESA 1V3AA 2HC1A 2WGPA 4ZI4A 3QCNA 3V0GA 1EENA 2OZ5A 2AHSA 2I6MA 4WTYA 4KI9A 2SHPA 2F6WA 2B3OA 1BZJA 5K9WA 3ZMQA 2G6ZA 1OEVA 5BZZA 1BZHA 2IMGA 1ZZWA 2QDCA 2CM8A 4ERCA 1WRMA 2I4EA 1P15A 1WAXA 5K22A 1RPMA 4QAPA 2PSZA 3AWFA 4S0GA 4DGPA 5K25A 1ZCLA 3D9CA 1L8KA 1J4XA 4OHHA 4NNDA 1OEUA 2BZLA 2QDPA 2OOQA 4NYHA 3A5JA 5GTJA 2B4SA 5J8RA 4D3QA 3CM3A 2E0TA 3O4TA 3AWEA 3RGOA 2HY3A 4QAHA 3F9AA 4R30A 3BM8A 2AZRA 4JBCA 2Q47A 4KYQA 2Y96A 3QKQA 2VEVA 1OEOX 4KYRA 5KABA 2M3VA 1A5YA 1Q6SA 5KACA 4JMJA 2PI7A 3BRHA 3M4UA 2NT7A 2CM2A 4GFVA 2I6PA 1OHEA 1L8GA 1PTVA 2I75A 2R0BA 2F46A 4WOHA 5HDEA 2B4PA 2I42A 4D3RA 2H4GA 1NO6A 2F6ZA 3LJ8A 4RH9A 4AZ1A 3RGQA 4RDDA 4IKCA 3B7OA 4H34A 3QCIA 3EU0A 4YR8B 4JNBA 5BZXA 2A8BA 2NV5A 2QCTA 3QKPA 3QCEA 2CJZA 2OC3A 4Z6BA 3BLTA 1OHDA 1BZCA 3S3FA 4Y2EA 1T48A 2H4KA 3NMEA 3D1HA 3MOZA 1PTTA 3ZV2A 2RF6A 2I3UA 4Y14A 3CWEA 1PH0A 2F6TA 1ONZA 2J16A 3PS5A 1Q1MA 3S3KA 2CNIA 5K23A 4QBEA 2I4GA 4GRZA 2QBQA 3F99A 2HNQA 2P4DA 5KA3A 2CNHA 4NX8A 2CMAA 3EZZA 2FH7A 5AWXA 4HRFA 1Q6MA 2H4VA 1GFYA 2CM3A 2CMBA 2ZMMA 4D3PA 1QXKA 2VEXA 2PT0A 1G7GA 4RI4A 1ZC0A 5KA7A 1LQFA 2I6JA 2HXPA 1NWEA 2QDMA 1PTUA 1C85A 2BGDA 2NT2A 1YFOA 3QCKA 5K9VA 2I4HA 1C88A 2VEWA 2NLKA 1KAVA 1T4JA 4YAAA 1NL9A 3GXHA 1Q6NA 2JJDA 4OHIA 4BPCA 3SMEA 4OHEA 1G4US 3QCJA 3QCFA 2PBNA 4R0TA 1ECVA 2ESBA 4GE5A 1KAKA 1T49A 1RXDA 1U24A 3O4SA 4GE6A 5I6VA 1XM2A 4MBBA 2BGEA 3A5KA 3BLUA 2BIJA 4ZN5A 3V0FA 2J16B 3EB1A 1YTSA 4RI5A 1MKPA 1XXPA 3I7ZA 3AWGA 1C87A 1X24A 2B4OA 1YTNA 3QCLA 2ZN7A 3QCCA 3I80A 5KA9A 5EHRA 3F81A 1M3GA 3D1QA 3V0HA 4GFUA 4BJOA 1C83A 5EHPA 1EEOA 4RH5A 4RHGA 1PTYA 1G1FA 1QZ0A 3ZMPA 5LXQB 1I57A 1JLNA 1ONYA 1PA1A 1Q6JA 1NNYA 2CNGA 1OHCA 1G7FA 3S4OA 3U96A 2G59A 1YGRA 1YWFA 3MOWA 1SUGA 3GXGA 3O4UA 1PA9A 1G1HA 4JMKA 2A3KA 2VEYA 2I6OA 2HC2A 3SR9A 3QCMA 5MMZB 4OHDA 3S4EA 4HJPA 3I36A 1WCHA 2QBSA 3OLRA 2VEUA 1AAXA 1XBOA 3EMUA 5K24A 1YTWA 3RZ2A 3H2XA 2H02A 4WU3A 1C86A 1Q6TA 2GP0A 1XXVA 2Y2FA 1YZ4A 2FJMA 1OETA 2DXPA 3ZM3A 2F6YA 4WU2A 1ZCKA 3V0JA 3ZM1A 2NTAA 4OHLA 2F6FA 2QCJA 3RO1A 1YN9A 3EAXA 3O5XA 2CMCA 4GWFA 3S3HA 2CFVA 4I8NA 4DGXA 5IBSA 4ZRTA 4ICZA 5BX1A 1NZ7A 3O3LA 2HCMA 2GJTA 1U25A 1PXHA 2I3RA 3ZM2A 4QUNA 1G1GA 3QCGA 2HVLA 2H03A
chains in the Genus database with same CATH superfamily
2MBCA 2J17A 3D42A 4H1OA 1I9SA 4B04A 2B4UA 3S3EA 2UUOA 2QBRA 2Y67A 4PYHA 3F41A 2I6IA 2BV5A 1E0DA 2CNEA 1JBWA 2F71A 4GE2A 1C84A 1YPTA 1NWLA 2YDUA 2PQ5A 4TVVA 1FQ1A 4GRYA 1G4WR 1R6HA 4GS0A 3ZM6A 2NZ6A 4NWFA 4NWGA 2WJPA 2B49A 1JF7A 5KAAA 2P6XA 3F9BA 4PVGA 5KA8A 5KA0A 1FPRA 2F70A 2UAGA 3ZM0A 2B07A 2GC6A 4QUMA 5M43A 3V0EA 4J51A 2CM7A 2I5XA 2FJNA 5KADA 2OUDA 4R0SA 5A5EA 1LARA 4RKKA 1VHRA 3V0DA 2HB1A 2I1YA 2Y66A 5KA2A 3MMJA 3QCBA 5BUGA 1D5RA 3D44A 5KA1A 3N0AA 1XRIA 2C7SA 4QBWA 2QBPA 1I9TA 2HNPA 3D1OA 2PA5A 1LYVA 1U26A 3QCDA 2VTDA 3QCHA 2F6VA 5IBMA 2GWOA 3V0IA 2H04A 1Q6PA 2XPCA 4HJQA 4CVMA 2Q05A 1GWZA 2GCAA 5KA4A 1PYNA 1YGUA 2C46A 1OEMX 2CNFA 3OMHA 2QEPA 1FPZA 1OESA 1V3AA 2HC1A 2WGPA 4ZI4A 3QCNA 2GCBA 3V0GA 1EENA 4HV4A 2OZ5A 2AHSA 2I6MA 4WTYA 1W78A 4KI9A 2SHPA 2F6WA 2B3OA 1BZJA 5K9WA 3ZMQA 4BUBA 2G6ZA 1OEVA 5BZZA 1BZHA 2IMGA 1ZZWA 2QDCA 2CM8A 1JBVA 4ERCA 2VORA 1WRMA 2I4EA 1P15A 3PYZA 1WAXA 2UUPA 5K22A 1RPMA 4QAPA 2PSZA 3AWFA 4S0GA 4DGPA 5A5FA 5K25A 1ZCLA 3D9CA 1L8KA 1J4XA 2Y68A 4OHHA 4NNDA 1OEUA 2BZLA 2QDPA 2OOQA 4NYHA 3A5JA 5GTJA 2B4SA 5J8RA 4D3QA 3CM3A 2GC5A 2E0TA 3O4TA 3AWEA 1E8CA 3RGOA 2HY3A 4QAHA 3F9AA 4R30A 3BM8A 2AZRA 4JBCA 2Q47A 4KYQA 2Y96A 3QKQA 2VEVA 1OEOX 4KYRA 5KABA 2M3VA 1A5YA 1Q6SA 5KACA 4JMJA 4CVLA 4QF5A 2PI7A 3BRHA 3M4UA 1P31A 2NT7A 2CM2A 4GFVA 2I6PA 1OHEA 1L8GA 1PTVA 2I75A 2R0BA 2F46A 3MVNA 4WOHA 5HDEA 2B4PA 2I42A 4D3RA 2H4GA 1NO6A 2F6ZA 3LJ8A 4RH9A 4AZ1A 3RGQA 4RDDA 4IKCA 3B7OA 2X5OA 4H34A 3QCIA 3EU0A 4C13A 4YR8B 3N2AA 4JNBA 5BZXA 2A8BA 2NV5A 2F00A 2QCTA 3QKPA 3ZL8A 3QCEA 2CJZA 2OC3A 4Z6BA 3BLTA 1OHDA 1BZCA 3S3FA 1W7KA 1O5ZA 4Y2EA 1T48A 2H4KA 3NMEA 3D1HA 3MOZA 1PTTA 3ZV2A 2RF6A 2I3UA 4Y14A 3CWEA 1PH0A 2F6TA 1ONZA 2J16A 3PS5A 1Q1MA 3S3KA 2CNIA 5K23A 4QBEA 2I4GA 4GRZA 2QBQA 3F99A 2HNQA 2P4DA 5KA3A 1GQYA 2CNHA 4NX8A 2CMAA 2VOSA 3EZZA 2FH7A 5AWXA 4HRFA 1Q6MA 2H4VA 1GFYA 2CM3A 1GQQA 2CMBA 2ZMMA 4D3PA 1QXKA 2VEXA 2PT0A 1G7GA 4RI4A 1ZC0A 5KA7A 1LQFA 2I6JA 2HXPA 1NWEA 2QDMA 1PTUA 1C85A 2BGDA 2NT2A 1YFOA 3QCKA 2JFHA 5K9VA 2I4HA 3HN7A 1C88A 1J6UA 2VEWA 2NLKA 2JFGA 1KAVA 4BUCA 1T4JA 4YAAA 1NL9A 3GXHA 1Q6NA 2JJDA 4OHIA 4BPCA 3SMEA 4OHEA 1G4US 3QCJA 3QCFA 2PBNA 1EEHA 4R0TA 1ECVA 2AM1A 4ZIYA 2ESBA 3NRSA 4GE5A 1KAKA 2JFFA 1T49A 1RXDA 1U24A 3O4SA 4GE6A 5I6VA 1XM2A 4MBBA 2BGEA 3A5KA 3BLUA 2BIJA 4ZN5A 3V0FA 2J16B 3EB1A 1YTSA 4RI5A 1MKPA 1XXPA 3I7ZA 3AWGA 1C87A 1X24A 2B4OA 1YTNA 3QCLA 2ZN7A 3QCCA 3I80A 5KA9A 5EHRA 3F81A 1M3GA 3D1QA 3V0HA 4GFUA 4BJOA 1C83A 5EHPA 1EEOA 4RH5A 4RHGA 1PTYA 1G1FA 1QZ0A 3ZMPA 5LXQB 4C12A 1I57A 1JLNA 1ONYA 1PA1A 1Q6JA 1NNYA 2CNGA 1OHCA 1G7FA 3S4OA 3U96A 2Y1OA 2G59A 1GG4A 1YGRA 1YWFA 3MOWA 1SUGA 3GXGA 2VTEA 3O4UA 1PA9A 1G1HA 1P3DA 4JMKA 2A3KA 2VEYA 2I6OA 2HC2A 3SR9A 3QCMA 3ZM5A 5MMZB 4OHDA 3S4EA 4HJPA 3I36A 1WCHA 3QCZA 2QBSA 3OLRA 2VEUA 1AAXA 1XBOA 3EMUA 5K24A 1YTWA 3RZ2A 3H2XA 2H02A 4WU3A 1C86A 1Q6TA 1UAGA 4CVKA 3LK7A 2GP0A 1XXVA 2Y2FA 1YZ4A 2FJMA 1OETA 3UAGA 2DXPA 3ZM3A 2F6YA 2AM2A 4WU2A 1ZCKA 2XJAA 3V0JA 1FGSA 2NTAA 4OHLA 3ZM1A 2F6FA 2QCJA 3RO1A 1YN9A 3EAXA 3O5XA 2CMCA 4GWFA 3S3HA 2CFVA 4I8NA 4QDIA 4DGXA 5IBSA 4ZRTA 4ICZA 5BX1A 1NZ7A 3O3LA 2HCMA 2GJTA 1U25A 1PXHA 2I3RA 2WTZA 3ZM2A 4UAGA 4QUNA 1G1GA 3QCGA 2HVLA 2H03A
chains in the Genus database with same CATH topology
2MBCA 2J17A 3D42A 4H1OA 1I9SA 4B04A 2B4UA 3S3EA 2QBRA 4PYHA 3F41A 2I6IA 2BV5A 2CNEA 2F71A 4GE2A 1C84A 1YPTA 1NWLA 2YDUA 2PQ5A 4TVVA 1FQ1A 4GRYA 1G4WR 1R6HA 4GS0A 2NZ6A 4NWFA 4NWGA 2B49A 1JF7A 5KAAA 2P6XA 3F9BA 4PVGA 5KA8A 5KA0A 1FPRA 2F70A 3ZM0A 2B07A 4QUMA 5M43A 3V0EA 4J51A 2CM7A 2I5XA 2FJNA 5KADA 2OUDA 4R0SA 1LARA 4RKKA 1VHRA 3V0DA 2HB1A 2I1YA 5KA2A 3MMJA 3QCBA 5BUGA 1D5RA 3D44A 5KA1A 3N0AA 1XRIA 2C7SA 4QBWA 2QBPA 1I9TA 2HNPA 3D1OA 2PA5A 1LYVA 1U26A 3QCDA 3QCHA 2F6VA 5IBMA 2GWOA 3V0IA 2H04A 1Q6PA 4HJQA 2Q05A 1GWZA 5KA4A 1PYNA 1YGUA 2C46A 1OEMX 2CNFA 3OMHA 2QEPA 1FPZA 1OESA 1V3AA 2HC1A 2WGPA 4ZI4A 3QCNA 3V0GA 1EENA 2OZ5A 2AHSA 2I6MA 4WTYA 4KI9A 2SHPA 2F6WA 2B3OA 1BZJA 5K9WA 3ZMQA 2G6ZA 1OEVA 5BZZA 1BZHA 2IMGA 1ZZWA 2QDCA 2CM8A 4ERCA 1WRMA 2I4EA 1P15A 1WAXA 5K22A 1RPMA 4QAPA 2PSZA 3AWFA 4S0GA 4DGPA 5K25A 1ZCLA 3D9CA 1L8KA 1J4XA 4OHHA 4NNDA 1OEUA 2BZLA 2QDPA 2OOQA 4NYHA 3A5JA 5GTJA 2B4SA 5J8RA 4D3QA 3CM3A 2E0TA 3O4TA 3AWEA 3RGOA 2HY3A 4QAHA 3F9AA 4R30A 3BM8A 2AZRA 4JBCA 2Q47A 4KYQA 2Y96A 3QKQA 2VEVA 1OEOX 4KYRA 5KABA 2M3VA 1A5YA 1Q6SA 5KACA 4JMJA 2PI7A 3BRHA 3M4UA 2NT7A 2CM2A 4GFVA 2I6PA 1OHEA 1L8GA 1PTVA 2I75A 2R0BA 2F46A 4WOHA 5HDEA 2B4PA 2I42A 4D3RA 2H4GA 1NO6A 2F6ZA 3LJ8A 4RH9A 4AZ1A 3RGQA 4RDDA 4IKCA 3B7OA 4H34A 3QCIA 3EU0A 4YR8B 4JNBA 5BZXA 2A8BA 2NV5A 2QCTA 3QKPA 3QCEA 2CJZA 2OC3A 4Z6BA 3BLTA 1OHDA 1BZCA 3S3FA 4Y2EA 1T48A 2H4KA 3NMEA 3D1HA 3MOZA 1PTTA 3ZV2A 2RF6A 2I3UA 4Y14A 3CWEA 1PH0A 2F6TA 1ONZA 2J16A 3PS5A 1Q1MA 3S3KA 2CNIA 5K23A 4QBEA 2I4GA 4GRZA 2QBQA 3F99A 2HNQA 2P4DA 5KA3A 2CNHA 4NX8A 2CMAA 3EZZA 2FH7A 5AWXA 4HRFA 1Q6MA 2H4VA 1GFYA 2CM3A 2CMBA 2ZMMA 4D3PA 1QXKA 2VEXA 2PT0A 1G7GA 4RI4A 1ZC0A 5KA7A 1LQFA 2I6JA 2HXPA 1NWEA 2QDMA 1PTUA 1C85A 2BGDA 2NT2A 1YFOA 3QCKA 5K9VA 2I4HA 1C88A 2VEWA 2NLKA 1KAVA 1T4JA 4YAAA 1NL9A 3GXHA 1Q6NA 2JJDA 4OHIA 4BPCA 3SMEA 4OHEA 1G4US 3QCJA 3QCFA 2PBNA 4R0TA 1ECVA 2ESBA 4GE5A 1KAKA 1T49A 1RXDA 1U24A 3O4SA 4GE6A 5I6VA 1XM2A 4MBBA 2BGEA 3A5KA 3BLUA 2BIJA 4ZN5A 3V0FA 2J16B 3EB1A 1YTSA 4RI5A 1MKPA 1XXPA 3I7ZA 3AWGA 1C87A 1X24A 2B4OA 1YTNA 3QCLA 2ZN7A 3QCCA 3I80A 5KA9A 5EHRA 3F81A 1M3GA 3D1QA 3V0HA 4GFUA 4BJOA 1C83A 5EHPA 1EEOA 4RH5A 4RHGA 1PTYA 1G1FA 1QZ0A 3ZMPA 5LXQB 1I57A 1JLNA 1ONYA 1PA1A 1Q6JA 1NNYA 2CNGA 1OHCA 1G7FA 3S4OA 3U96A 2G59A 1YGRA 1YWFA 3MOWA 1SUGA 3GXGA 3O4UA 1PA9A 1G1HA 4JMKA 2A3KA 2VEYA 2I6OA 2HC2A 3SR9A 3QCMA 5MMZB 4OHDA 3S4EA 4HJPA 3I36A 1WCHA 2QBSA 3OLRA 2VEUA 1AAXA 1XBOA 3EMUA 5K24A 1YTWA 3RZ2A 3H2XA 2H02A 4WU3A 1C86A 1Q6TA 2GP0A 1XXVA 2Y2FA 1YZ4A 2FJMA 1OETA 2DXPA 3ZM3A 2F6YA 4WU2A 1ZCKA 3V0JA 3ZM1A 2NTAA 4OHLA 2F6FA 2QCJA 3RO1A 1YN9A 3EAXA 3O5XA 2CMCA 4GWFA 3S3HA 2CFVA 4I8NA 4DGXA 5IBSA 4ZRTA 4ICZA 5BX1A 1NZ7A 3O3LA 2HCMA 2GJTA 1U25A 1PXHA 2I3RA 3ZM2A 4QUNA 1G1GA 3QCGA 2HVLA 2H03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MBC A;  2J17 A;  3D42 A;  4H1O A;  1I9S A;  4B04 A;  2B4U A;  3S3E A;  2QBR A;  4PYH A;  3F41 A;  2I6I A;  2BV5 A;  2CNE A;  2F71 A;  4GE2 A;  1C84 A;  1YPT A;  1NWL A;  2YDU A;  2PQ5 A;  4TVV A;  1FQ1 A;  4GRY A;  1G4W R;  1R6H A;  4GS0 A;  2NZ6 A;  4NWF A;  4NWG A;  2B49 A;  1JF7 A;  5KAA A;  2P6X A;  3F9B A;  4PVG A;  5KA8 A;  5KA0 A;  1FPR A;  2F70 A;  3ZM0 A;  2B07 A;  4QUM A;  5M43 A;  3V0E A;  4J51 A;  2CM7 A;  2I5X A;  2FJN A;  5KAD A;  2OUD A;  4R0S A;  1LAR A;  4RKK A;  1VHR A;  3V0D A;  2HB1 A;  2I1Y A;  5KA2 A;  3MMJ A;  3QCB A;  5BUG A;  1D5R A;  3D44 A;  5KA1 A;  3N0A A;  1XRI A;  2C7S A;  4QBW A;  2QBP A;  1I9T A;  2HNP A;  3D1O A;  2PA5 A;  1LYV A;  1U26 A;  3QCD A;  3QCH A;  2F6V A;  5IBM A;  2GWO A;  3V0I A;  2H04 A;  1Q6P A;  4HJQ A;  2Q05 A;  1GWZ A;  5KA4 A;  1PYN A;  1YGU A;  2C46 A;  1OEM X;  2CNF A;  3OMH A;  2QEP A;  1FPZ A;  1OES A;  1V3A A;  2HC1 A;  2WGP A;  4ZI4 A;  3QCN A;  3V0G A;  1EEN A;  2OZ5 A;  2AHS A;  2I6M A;  4WTY A;  4KI9 A;  2SHP A;  2F6W A;  2B3O A;  1BZJ A;  5K9W A;  3ZMQ A;  2G6Z A;  1OEV A;  5BZZ A;  1BZH A;  2IMG A;  1ZZW A;  2QDC A;  2CM8 A;  4ERC A;  1WRM A;  2I4E A;  1P15 A;  1WAX A;  5K22 A;  1RPM A;  4QAP A;  2PSZ A;  3AWF A;  4S0G A;  4DGP A;  5K25 A;  1ZCL A;  3D9C A;  1L8K A;  1J4X A;  4OHH A;  4NND A;  1OEU A;  2BZL A;  2QDP A;  2OOQ A;  4NYH A;  3A5J A;  5GTJ A;  2B4S A;  5J8R A;  4D3Q A;  3CM3 A;  2E0T A;  3O4T A;  3AWE A;  3RGO A;  2HY3 A;  4QAH A;  3F9A A;  4R30 A;  3BM8 A;  2AZR A;  4JBC A;  2Q47 A;  4KYQ A;  2Y96 A;  3QKQ A;  2VEV A;  1OEO X;  4KYR A;  5KAB A;  2M3V A;  1A5Y A;  1Q6S A;  5KAC A;  4JMJ A;  2PI7 A;  3BRH A;  3M4U A;  2NT7 A;  2CM2 A;  4GFV A;  2I6P A;  1OHE A;  1L8G A;  1PTV A;  2I75 A;  2R0B A;  2F46 A;  4WOH A;  5HDE A;  2B4P A;  2I42 A;  4D3R A;  2H4G A;  1NO6 A;  2F6Z A;  3LJ8 A;  4RH9 A;  4AZ1 A;  3RGQ A;  4RDD A;  4IKC A;  3B7O A;  4H34 A;  3QCI A;  3EU0 A;  4YR8 B;  4JNB A;  5BZX A;  2A8B A;  2NV5 A;  2QCT A;  3QKP A;  3QCE A;  2CJZ A;  2OC3 A;  4Z6B A;  3BLT A;  1OHD A;  1BZC A;  3S3F A;  4Y2E A;  1T48 A;  2H4K A;  3NME A;  3D1H A;  3MOZ A;  1PTT A;  3ZV2 A;  2RF6 A;  2I3U A;  4Y14 A;  3CWE A;  1PH0 A;  2F6T A;  1ONZ A;  2J16 A;  3PS5 A;  1Q1M A;  3S3K A;  2CNI A;  5K23 A;  4QBE A;  2I4G A;  4GRZ A;  2QBQ A;  3F99 A;  2HNQ A;  2P4D A;  5KA3 A;  2CNH A;  4NX8 A;  2CMA A;  3EZZ A;  2FH7 A;  5AWX A;  4HRF A;  1Q6M A;  2H4V A;  1GFY A;  2CM3 A;  2CMB A;  2ZMM A;  4D3P A;  1QXK A;  2VEX A;  2PT0 A;  1G7G A;  4RI4 A;  1ZC0 A;  5KA7 A;  1LQF A;  2I6J A;  2HXP A;  1NWE A;  2QDM A;  1PTU A;  1C85 A;  2BGD A;  2NT2 A;  1YFO A;  3QCK A;  5K9V A;  2I4H A;  1C88 A;  2VEW A;  2NLK A;  1KAV A;  1T4J A;  4YAA A;  1NL9 A;  3GXH A;  1Q6N A;  2JJD A;  4OHI A;  4BPC A;  3SME A;  4OHE A;  1G4U S;  3QCJ A;  3QCF A;  2PBN A;  4R0T A;  1ECV A;  2ESB A;  4GE5 A;  1KAK A;  1T49 A;  1RXD A;  1U24 A;  3O4S A;  4GE6 A;  5I6V A;  1XM2 A;  4MBB A;  2BGE A;  3A5K A;  3BLU A;  2BIJ A;  4ZN5 A;  3V0F A;  2J16 B;  3EB1 A;  1YTS A;  4RI5 A;  1MKP A;  1XXP A;  3I7Z A;  3AWG A;  1C87 A;  1X24 A;  2B4O A;  1YTN A;  3QCL A;  2ZN7 A;  3QCC A;  3I80 A;  5KA9 A;  5EHR A;  3F81 A;  1M3G A;  3D1Q A;  3V0H A;  4GFU A;  4BJO A;  1C83 A;  5EHP A;  1EEO A;  4RH5 A;  4RHG A;  1PTY A;  1G1F A;  1QZ0 A;  3ZMP A;  5LXQ B;  1I57 A;  1JLN A;  1ONY A;  1PA1 A;  1Q6J A;  1NNY A;  2CNG A;  1OHC A;  1G7F A;  3S4O A;  3U96 A;  2G59 A;  1YGR A;  1YWF A;  3MOW A;  1SUG A;  3GXG A;  3O4U A;  1PA9 A;  1G1H A;  4JMK A;  2A3K A;  2VEY A;  2I6O A;  2HC2 A;  3SR9 A;  3QCM A;  5MMZ B;  4OHD A;  3S4E A;  4HJP A;  3I36 A;  1WCH A;  2QBS A;  3OLR A;  2VEU A;  1AAX A;  1XBO A;  3EMU A;  5K24 A;  1YTW A;  3RZ2 A;  3H2X A;  2H02 A;  4WU3 A;  1C86 A;  1Q6T A;  2GP0 A;  1XXV A;  2Y2F A;  1YZ4 A;  2FJM A;  1OET A;  2DXP A;  3ZM3 A;  2F6Y A;  4WU2 A;  1ZCK A;  3V0J A;  3ZM1 A;  2NTA A;  4OHL A;  2F6F A;  2QCJ A;  3RO1 A;  1YN9 A;  3EAX A;  3O5X A;  2CMC A;  4GWF A;  3S3H A;  2CFV A;  4I8N A;  4DGX A;  5IBS A;  4ZRT A;  4ICZ A;  5BX1 A;  1NZ7 A;  3O3L A;  2HCM A;  2GJT A;  1U25 A;  1PXH A;  2I3R A;  3ZM2 A;  4QUN A;  1G1G A;  3QCG A;  2HVL A;  2H03 A; 
#chains in the Genus database with same CATH topology
 2MBC A;  2J17 A;  3D42 A;  4H1O A;  1I9S A;  4B04 A;  2B4U A;  3S3E A;  2UUO A;  2QBR A;  2Y67 A;  4PYH A;  3F41 A;  2I6I A;  2BV5 A;  1E0D A;  2CNE A;  1JBW A;  2F71 A;  4GE2 A;  1C84 A;  1YPT A;  1NWL A;  2YDU A;  2PQ5 A;  4TVV A;  1FQ1 A;  4GRY A;  1G4W R;  1R6H A;  4GS0 A;  3ZM6 A;  2NZ6 A;  4NWF A;  4NWG A;  2WJP A;  2B49 A;  1JF7 A;  5KAA A;  2P6X A;  3F9B A;  4PVG A;  5KA8 A;  5KA0 A;  1FPR A;  2F70 A;  2UAG A;  3ZM0 A;  2B07 A;  2GC6 A;  4QUM A;  5M43 A;  3V0E A;  4J51 A;  2CM7 A;  2I5X A;  2FJN A;  5KAD A;  2OUD A;  4R0S A;  5A5E A;  1LAR A;  4RKK A;  1VHR A;  3V0D A;  2HB1 A;  2I1Y A;  2Y66 A;  5KA2 A;  3MMJ A;  3QCB A;  5BUG A;  1D5R A;  3D44 A;  5KA1 A;  3N0A A;  1XRI A;  2C7S A;  4QBW A;  2QBP A;  1I9T A;  2HNP A;  3D1O A;  2PA5 A;  1LYV A;  1U26 A;  3QCD A;  2VTD A;  3QCH A;  2F6V A;  5IBM A;  2GWO A;  3V0I A;  2H04 A;  1Q6P A;  2XPC A;  4HJQ A;  4CVM A;  2Q05 A;  1GWZ A;  2GCA A;  5KA4 A;  1PYN A;  1YGU A;  2C46 A;  1OEM X;  2CNF A;  3OMH A;  2QEP A;  1FPZ A;  1OES A;  1V3A A;  2HC1 A;  2WGP A;  4ZI4 A;  3QCN A;  2GCB A;  3V0G A;  1EEN A;  4HV4 A;  2OZ5 A;  2AHS A;  2I6M A;  4WTY A;  1W78 A;  4KI9 A;  2SHP A;  2F6W A;  2B3O A;  1BZJ A;  5K9W A;  3ZMQ A;  4BUB A;  2G6Z A;  1OEV A;  5BZZ A;  1BZH A;  2IMG A;  1ZZW A;  2QDC A;  2CM8 A;  1JBV A;  4ERC A;  2VOR A;  1WRM A;  2I4E A;  1P15 A;  3PYZ A;  1WAX A;  2UUP A;  5K22 A;  1RPM A;  4QAP A;  2PSZ A;  3AWF A;  4S0G A;  4DGP A;  5A5F A;  5K25 A;  1ZCL A;  3D9C A;  1L8K A;  1J4X A;  2Y68 A;  4OHH A;  4NND A;  1OEU A;  2BZL A;  2QDP A;  2OOQ A;  4NYH A;  3A5J A;  5GTJ A;  2B4S A;  5J8R A;  4D3Q A;  3CM3 A;  2GC5 A;  2E0T A;  3O4T A;  3AWE A;  1E8C A;  3RGO A;  2HY3 A;  4QAH A;  3F9A A;  4R30 A;  3BM8 A;  2AZR A;  4JBC A;  2Q47 A;  4KYQ A;  2Y96 A;  3QKQ A;  2VEV A;  1OEO X;  4KYR A;  5KAB A;  2M3V A;  1A5Y A;  1Q6S A;  5KAC A;  4JMJ A;  4CVL A;  4QF5 A;  2PI7 A;  3BRH A;  3M4U A;  1P31 A;  2NT7 A;  2CM2 A;  4GFV A;  2I6P A;  1OHE A;  1L8G A;  1PTV A;  2I75 A;  2R0B A;  2F46 A;  3MVN A;  4WOH A;  5HDE A;  2B4P A;  2I42 A;  4D3R A;  2H4G A;  1NO6 A;  2F6Z A;  3LJ8 A;  4RH9 A;  4AZ1 A;  3RGQ A;  4RDD A;  4IKC A;  3B7O A;  2X5O A;  4H34 A;  3QCI A;  3EU0 A;  4C13 A;  4YR8 B;  3N2A A;  4JNB A;  5BZX A;  2A8B A;  2NV5 A;  2F00 A;  2QCT A;  3QKP A;  3ZL8 A;  3QCE A;  2CJZ A;  2OC3 A;  4Z6B A;  3BLT A;  1OHD A;  1BZC A;  3S3F A;  1W7K A;  1O5Z A;  4Y2E A;  1T48 A;  2H4K A;  3NME A;  3D1H A;  3MOZ A;  1PTT A;  3ZV2 A;  2RF6 A;  2I3U A;  4Y14 A;  3CWE A;  1PH0 A;  2F6T A;  1ONZ A;  2J16 A;  3PS5 A;  1Q1M A;  3S3K A;  2CNI A;  5K23 A;  4QBE A;  2I4G A;  4GRZ A;  2QBQ A;  3F99 A;  2HNQ A;  2P4D A;  5KA3 A;  1GQY A;  2CNH A;  4NX8 A;  2CMA A;  2VOS A;  3EZZ A;  2FH7 A;  5AWX A;  4HRF A;  1Q6M A;  2H4V A;  1GFY A;  2CM3 A;  1GQQ A;  2CMB A;  2ZMM A;  4D3P A;  1QXK A;  2VEX A;  2PT0 A;  1G7G A;  4RI4 A;  1ZC0 A;  5KA7 A;  1LQF A;  2I6J A;  2HXP A;  1NWE A;  2QDM A;  1PTU A;  1C85 A;  2BGD A;  2NT2 A;  1YFO A;  3QCK A;  2JFH A;  5K9V A;  2I4H A;  3HN7 A;  1C88 A;  1J6U A;  2VEW A;  2NLK A;  2JFG A;  1KAV A;  4BUC A;  1T4J A;  4YAA A;  1NL9 A;  3GXH A;  1Q6N A;  2JJD A;  4OHI A;  4BPC A;  3SME A;  4OHE A;  1G4U S;  3QCJ A;  3QCF A;  2PBN A;  1EEH A;  4R0T A;  1ECV A;  2AM1 A;  4ZIY A;  2ESB A;  3NRS A;  4GE5 A;  1KAK A;  2JFF A;  1T49 A;  1RXD A;  1U24 A;  3O4S A;  4GE6 A;  5I6V A;  1XM2 A;  4MBB A;  2BGE A;  3A5K A;  3BLU A;  2BIJ A;  4ZN5 A;  3V0F A;  2J16 B;  3EB1 A;  1YTS A;  4RI5 A;  1MKP A;  1XXP A;  3I7Z A;  3AWG A;  1C87 A;  1X24 A;  2B4O A;  1YTN A;  3QCL A;  2ZN7 A;  3QCC A;  3I80 A;  5KA9 A;  5EHR A;  3F81 A;  1M3G A;  3D1Q A;  3V0H A;  4GFU A;  4BJO A;  1C83 A;  5EHP A;  1EEO A;  4RH5 A;  4RHG A;  1PTY A;  1G1F A;  1QZ0 A;  3ZMP A;  5LXQ B;  4C12 A;  1I57 A;  1JLN A;  1ONY A;  1PA1 A;  1Q6J A;  1NNY A;  2CNG A;  1OHC A;  1G7F A;  3S4O A;  3U96 A;  2Y1O A;  2G59 A;  1GG4 A;  1YGR A;  1YWF A;  3MOW A;  1SUG A;  3GXG A;  2VTE A;  3O4U A;  1PA9 A;  1G1H A;  1P3D A;  4JMK A;  2A3K A;  2VEY A;  2I6O A;  2HC2 A;  3SR9 A;  3QCM A;  3ZM5 A;  5MMZ B;  4OHD A;  3S4E A;  4HJP A;  3I36 A;  1WCH A;  3QCZ A;  2QBS A;  3OLR A;  2VEU A;  1AAX A;  1XBO A;  3EMU A;  5K24 A;  1YTW A;  3RZ2 A;  3H2X A;  2H02 A;  4WU3 A;  1C86 A;  1Q6T A;  1UAG A;  4CVK A;  3LK7 A;  2GP0 A;  1XXV A;  2Y2F A;  1YZ4 A;  2FJM A;  1OET A;  3UAG A;  2DXP A;  3ZM3 A;  2F6Y A;  2AM2 A;  4WU2 A;  1ZCK A;  2XJA A;  3V0J A;  1FGS A;  2NTA A;  4OHL A;  3ZM1 A;  2F6F A;  2QCJ A;  3RO1 A;  1YN9 A;  3EAX A;  3O5X A;  2CMC A;  4GWF A;  3S3H A;  2CFV A;  4I8N A;  4QDI A;  4DGX A;  5IBS A;  4ZRT A;  4ICZ A;  5BX1 A;  1NZ7 A;  3O3L A;  2HCM A;  2GJT A;  1U25 A;  1PXH A;  2I3R A;  2WTZ A;  3ZM2 A;  4UAG A;  4QUN A;  1G1G A;  3QCG A;  2HVL A;  2H03 A; 
#chains in the Genus database with same CATH homology
 2MBC A;  2J17 A;  3D42 A;  4H1O A;  1I9S A;  4B04 A;  2B4U A;  3S3E A;  2QBR A;  4PYH A;  3F41 A;  2I6I A;  2BV5 A;  2CNE A;  2F71 A;  4GE2 A;  1C84 A;  1YPT A;  1NWL A;  2YDU A;  2PQ5 A;  4TVV A;  1FQ1 A;  4GRY A;  1G4W R;  1R6H A;  4GS0 A;  2NZ6 A;  4NWF A;  4NWG A;  2B49 A;  1JF7 A;  5KAA A;  2P6X A;  3F9B A;  4PVG A;  5KA8 A;  5KA0 A;  1FPR A;  2F70 A;  3ZM0 A;  2B07 A;  4QUM A;  5M43 A;  3V0E A;  4J51 A;  2CM7 A;  2I5X A;  2FJN A;  5KAD A;  2OUD A;  4R0S A;  1LAR A;  4RKK A;  1VHR A;  3V0D A;  2HB1 A;  2I1Y A;  5KA2 A;  3MMJ A;  3QCB A;  5BUG A;  1D5R A;  3D44 A;  5KA1 A;  3N0A A;  1XRI A;  2C7S A;  4QBW A;  2QBP A;  1I9T A;  2HNP A;  3D1O A;  2PA5 A;  1LYV A;  1U26 A;  3QCD A;  3QCH A;  2F6V A;  5IBM A;  2GWO A;  3V0I A;  2H04 A;  1Q6P A;  4HJQ A;  2Q05 A;  1GWZ A;  5KA4 A;  1PYN A;  1YGU A;  2C46 A;  1OEM X;  2CNF A;  3OMH A;  2QEP A;  1FPZ A;  1OES A;  1V3A A;  2HC1 A;  2WGP A;  4ZI4 A;  3QCN A;  3V0G A;  1EEN A;  2OZ5 A;  2AHS A;  2I6M A;  4WTY A;  4KI9 A;  2SHP A;  2F6W A;  2B3O A;  1BZJ A;  5K9W A;  3ZMQ A;  2G6Z A;  1OEV A;  5BZZ A;  1BZH A;  2IMG A;  1ZZW A;  2QDC A;  2CM8 A;  4ERC A;  1WRM A;  2I4E A;  1P15 A;  1WAX A;  5K22 A;  1RPM A;  4QAP A;  2PSZ A;  3AWF A;  4S0G A;  4DGP A;  5K25 A;  1ZCL A;  3D9C A;  1L8K A;  1J4X A;  4OHH A;  4NND A;  1OEU A;  2BZL A;  2QDP A;  2OOQ A;  4NYH A;  3A5J A;  5GTJ A;  2B4S A;  5J8R A;  4D3Q A;  3CM3 A;  2E0T A;  3O4T A;  3AWE A;  3RGO A;  2HY3 A;  4QAH A;  3F9A A;  4R30 A;  3BM8 A;  2AZR A;  4JBC A;  2Q47 A;  4KYQ A;  2Y96 A;  3QKQ A;  2VEV A;  1OEO X;  4KYR A;  5KAB A;  2M3V A;  1A5Y A;  1Q6S A;  5KAC A;  4JMJ A;  2PI7 A;  3BRH A;  3M4U A;  2NT7 A;  2CM2 A;  4GFV A;  2I6P A;  1OHE A;  1L8G A;  1PTV A;  2I75 A;  2R0B A;  2F46 A;  4WOH A;  5HDE A;  2B4P A;  2I42 A;  4D3R A;  2H4G A;  1NO6 A;  2F6Z A;  3LJ8 A;  4RH9 A;  4AZ1 A;  3RGQ A;  4RDD A;  4IKC A;  3B7O A;  4H34 A;  3QCI A;  3EU0 A;  4YR8 B;  4JNB A;  5BZX A;  2A8B A;  2NV5 A;  2QCT A;  3QKP A;  3QCE A;  2CJZ A;  2OC3 A;  4Z6B A;  3BLT A;  1OHD A;  1BZC A;  3S3F A;  4Y2E A;  1T48 A;  2H4K A;  3NME A;  3D1H A;  3MOZ A;  1PTT A;  3ZV2 A;  2RF6 A;  2I3U A;  4Y14 A;  3CWE A;  1PH0 A;  2F6T A;  1ONZ A;  2J16 A;  3PS5 A;  1Q1M A;  3S3K A;  2CNI A;  5K23 A;  4QBE A;  2I4G A;  4GRZ A;  2QBQ A;  3F99 A;  2HNQ A;  2P4D A;  5KA3 A;  2CNH A;  4NX8 A;  2CMA A;  3EZZ A;  2FH7 A;  5AWX A;  4HRF A;  1Q6M A;  2H4V A;  1GFY A;  2CM3 A;  2CMB A;  2ZMM A;  4D3P A;  1QXK A;  2VEX A;  2PT0 A;  1G7G A;  4RI4 A;  1ZC0 A;  5KA7 A;  1LQF A;  2I6J A;  2HXP A;  1NWE A;  2QDM A;  1PTU A;  1C85 A;  2BGD A;  2NT2 A;  1YFO A;  3QCK A;  5K9V A;  2I4H A;  1C88 A;  2VEW A;  2NLK A;  1KAV A;  1T4J A;  4YAA A;  1NL9 A;  3GXH A;  1Q6N A;  2JJD A;  4OHI A;  4BPC A;  3SME A;  4OHE A;  1G4U S;  3QCJ A;  3QCF A;  2PBN A;  4R0T A;  1ECV A;  2ESB A;  4GE5 A;  1KAK A;  1T49 A;  1RXD A;  1U24 A;  3O4S A;  4GE6 A;  5I6V A;  1XM2 A;  4MBB A;  2BGE A;  3A5K A;  3BLU A;  2BIJ A;  4ZN5 A;  3V0F A;  2J16 B;  3EB1 A;  1YTS A;  4RI5 A;  1MKP A;  1XXP A;  3I7Z A;  3AWG A;  1C87 A;  1X24 A;  2B4O A;  1YTN A;  3QCL A;  2ZN7 A;  3QCC A;  3I80 A;  5KA9 A;  5EHR A;  3F81 A;  1M3G A;  3D1Q A;  3V0H A;  4GFU A;  4BJO A;  1C83 A;  5EHP A;  1EEO A;  4RH5 A;  4RHG A;  1PTY A;  1G1F A;  1QZ0 A;  3ZMP A;  5LXQ B;  1I57 A;  1JLN A;  1ONY A;  1PA1 A;  1Q6J A;  1NNY A;  2CNG A;  1OHC A;  1G7F A;  3S4O A;  3U96 A;  2G59 A;  1YGR A;  1YWF A;  3MOW A;  1SUG A;  3GXG A;  3O4U A;  1PA9 A;  1G1H A;  4JMK A;  2A3K A;  2VEY A;  2I6O A;  2HC2 A;  3SR9 A;  3QCM A;  5MMZ B;  4OHD A;  3S4E A;  4HJP A;  3I36 A;  1WCH A;  2QBS A;  3OLR A;  2VEU A;  1AAX A;  1XBO A;  3EMU A;  5K24 A;  1YTW A;  3RZ2 A;  3H2X A;  2H02 A;  4WU3 A;  1C86 A;  1Q6T A;  2GP0 A;  1XXV A;  2Y2F A;  1YZ4 A;  2FJM A;  1OET A;  2DXP A;  3ZM3 A;  2F6Y A;  4WU2 A;  1ZCK A;  3V0J A;  3ZM1 A;  2NTA A;  4OHL A;  2F6F A;  2QCJ A;  3RO1 A;  1YN9 A;  3EAX A;  3O5X A;  2CMC A;  4GWF A;  3S3H A;  2CFV A;  4I8N A;  4DGX A;  5IBS A;  4ZRT A;  4ICZ A;  5BX1 A;  1NZ7 A;  3O3L A;  2HCM A;  2GJT A;  1U25 A;  1PXH A;  2I3R A;  3ZM2 A;  4QUN A;  1G1G A;  3QCG A;  2HVL A;  2H03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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