2FJNA

The structure of phosphotyrosine phosphatase 1b in complex with compound 2
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
289
structure length
289
Chain Sequence
KLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 97
structure length 289
sequence length 289
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-01-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2fjnA00
1C83A 2VEYA 4MBBA 4WOHA 1G7GA 4WU3A 1Q6MA 1EEOA 2BGDA 1V3AA 3A5KA 2H02A 4D3QA 3D42A 2CNGA 2QCTA 4HJQA 4QUMA 2A8BA 2B4UA 2BGEA 3QCGA 5KA2A 1BZJA 1OHEA 2H03A 4KYRA 1P15A 4HRFA 1Q6PA 3QCCA 2I4HA 4I8NA 2HVLA 2CNHA 2Y2FA 3V0IA 1YWFA 4J51A 4YR8B 1PTVA 2HNPA 1G4US 4GFVA 4JNBA 3S4OA 4AZ1A 2P4DA 4ZI4A 1U25A 4ZRTA 4GE5A 1T4JA 4WU2A 3NMEA 4Y14A 2I6OA 1M3GA 1OHDA 2PT0A 2QBPA 4GE2A 1G1FA 5K9WA 1JF7A 2H4KA 4BJOA 2QBRA 4TVVA 1PH0A 3OLRA 1I9TA 2B3OA 4QUNA 2B07A 1YN9A 3QKPA 3V0GA 5EHPA 2QBSA 4OHEA 3OMHA 3QCJA 3QCLA 5BZZA 1YTWA 1L8GA 5KABA 4PYHA 4NNDA 2F6TA 3N0AA 4GRYA 3EMUA 4OHIA 1KAVA 1OESA 3QCKA 4RH9A 2PI7A 3M4UA 1D5RA 4R0TA 2J16A 3BM8A 2GJTA 3D1QA 1XXPA 5KA0A 2I6PA 4Z6BA 2H4VA 1OETA 2NZ6A 4GS0A 5IBSA 1G7FA 2BV5A 4KI9A 4IKCA 4RI5A 1C84A 2FH7A 1QXKA 2F6WA 3AWGA 3S3FA 2A3KA 2CM7A 2QEPA 3O5XA 2PQ5A 3F9AA 1BZHA 2ZN7A 4OHHA 1U24A 2FJMA 1NL9A 2CMBA 1WRMA 4NWGA 5LXQB 4R30A 3F9BA 2MBCA 1OHCA 5BX1A 3AWFA 2F6FA 1YGRA 3S3HA 3LJ8A 4S0GA 1LQFA 2PA5A 2B4PA 2CMCA 3QCDA 3RGOA 3D44A 2P6XA 2CM8A 2SHPA 2QDMA 2BZLA 2NTAA 3MOWA 2I6JA 3F99A 2NLKA 1ZZWA 4RDDA 5GTJA 2J17A 1T48A 4H1OA 1RXDA 2CM3A 1LARA 2PSZA 2CNFA 2VEVA 4RH5A 2I4GA 1OEOX 1YTSA 1ECVA 3S3KA 2G59A 2FJNA 1XBOA 1NWEA 5K25A 1NO6A 4YAAA 3ZM0A 2CFVA 1PXHA 4DGPA 5KAAA 1AAXA 4WTYA 2F71A 2VEXA 3I80A 1Q6JA 2AHSA 2JJDA 3GXGA 3F81A 2CM2A 3F41A 2I1YA 2F70A 2PBNA 2H04A 3BLUA 2C46A 2AZRA 3RO1A 5EHRA 3QKQA 1U26A 3PS5A 4PVGA 1PTYA 1QZ0A 2GWOA 2OC3A 2I6MA 4RHGA 1YFOA 1ZCLA 1PA9A 5KA1A 4QBEA 1XXVA 1PYNA 2I5XA 2OOQA 3O3LA 2HY3A 3I36A 3QCFA 1YZ4A 2I75A 5MMZB 1J4XA 4NYHA 4JBCA 1YGUA 3QCMA 4GE6A 5KA4A 5KA8A 3AWEA 2F6ZA 4D3RA 1FPRA 3O4UA 1Q6SA 5AWXA 2GP0A 1A5YA 3ZMPA 4GFUA 3EB1A 2WGPA 1T49A 2M3VA 2VEUA 1Q6TA 4RI4A 3MOZA 2NT7A 4KYQA 5J8RA 1OEVA 2NT2A 1G4WR 4ZN5A 1ONYA 2HC1A 4QAHA 3QCBA 3SMEA 3S4EA 1WAXA 3QCHA 3ZM1A 1YTNA 1C87A 2F6VA 3BLTA 4JMKA 1Q6NA 4HJPA 2E0TA 3ZMQA 3ZM2A 1C88A 1RPMA 1LYVA 3GXHA 4JMJA 4NX8A 3QCIA 1FPZA 1R6HA 1SUGA 2CMAA 4NWFA 5I6VA 2HB1A 4QBWA 2ZMMA 1ZCKA 4GRZA 1FQ1A 3V0HA 5KADA 2QBQA 2Y96A 1ONZA 3BRHA 4OHLA 5IBMA 1PTUA 5M43A 1VHRA 1I57A 5KACA 1WCHA 1X24A 3EZZA 2I3RA 2QDCA 3RZ2A 1GFYA 1GWZA 5K24A 5K9VA 1XRIA 4D3PA 2CNEA 1PA1A 2R0BA 4R0SA 2B4OA 3V0EA 1PTTA 2F6YA 2HNQA 2DXPA 3EAXA 2I4EA 2B49A 2OZ5A 3D1OA 2HXPA 2OUDA 5KA9A 4Y2EA 1EENA 2VEWA 1JLNA 4GWFA 3EU0A 4B04A 3D9CA 4DGXA 3S3EA 1NNYA 2I3UA 1L8KA 2HC2A 4OHDA 1C85A 2ESBA 5KA3A 5BUGA 1KAKA 1NZ7A 5K22A 2QDPA 3I7ZA 3RGQA 3H2XA 3ZM3A 2H4GA 2G6ZA 5K23A 2I42A 2Q47A 2YDUA 4RKKA 2B4SA 3V0DA 3QCEA 1G1HA 2BIJA 2J16B 3QCNA 3D1HA 3A5JA 1OEMX 5KA7A 1YPTA 2RF6A 1I9SA 2IMGA 1C86A 4BPCA 1ZC0A 4H34A 2F46A 2I6IA 3U96A 3B7OA 2QCJA 3MMJA 3O4TA 4QAPA 2NV5A 2CNIA 2C7SA 4ERCA 2Q05A 1G1GA 5BZXA 3V0JA 3V0FA 3O4SA 2CJZA 1NWLA 1OEUA 3SR9A 1BZCA 2HCMA 1Q1MA 4ICZA 1MKPA 1XM2A 3ZV2A 3CWEA 3CM3A 5HDEA
chains in the Genus database with same CATH superfamily
1C83A 2VEYA 4MBBA 4WOHA 1G7GA 4QDIA 4WU3A 1Q6MA 1EEOA 2BGDA 1V3AA 3A5KA 2H02A 4D3QA 3D42A 2CNGA 2QCTA 4HJQA 4QUMA 2A8BA 2B4UA 2BGEA 3QCGA 5KA2A 1BZJA 1OHEA 2H03A 2JFHA 1P15A 4KYRA 4HRFA 1Q6PA 4ZIYA 3QCCA 4QF5A 2I4HA 2X5OA 4I8NA 2HVLA 2CNHA 2Y2FA 3V0IA 1YWFA 4J51A 2Y1OA 4YR8B 1PTVA 2HNPA 4C13A 1G4US 4GFVA 4JNBA 3S4OA 2JFFA 4AZ1A 2P4DA 4ZI4A 1U25A 4ZRTA 4GE5A 1T4JA 4WU2A 3NMEA 4Y14A 2I6OA 1M3GA 1GQYA 2Y67A 1OHDA 2PT0A 2QBPA 4GE2A 1G1FA 5K9WA 1JF7A 2H4KA 1W78A 2AM2A 2QBRA 4TVVA 4BJOA 1PH0A 3OLRA 1I9TA 2B3OA 4QUNA 2VORA 2B07A 1YN9A 3QKPA 3V0GA 2VOSA 2QBSA 4OHEA 5EHPA 3OMHA 3QCJA 3QCLA 5BZZA 1YTWA 1L8GA 5KABA 4PYHA 4NNDA 1FGSA 2F6TA 3N0AA 4GRYA 3EMUA 4OHIA 1KAVA 1OESA 3QCKA 4RH9A 2PI7A 3M4UA 1D5RA 4R0TA 2J16A 3BM8A 3N2AA 2GJTA 3D1QA 1XXPA 2GC6A 5KA0A 2I6PA 4Z6BA 3ZL8A 1P31A 2H4VA 4UAGA 2XJAA 1OETA 2NZ6A 4GS0A 5IBSA 1G7FA 2BV5A 4KI9A 4IKCA 4RI5A 1C84A 2FH7A 1QXKA 2F6WA 3AWGA 3S3FA 2A3KA 2CM7A 2QEPA 3O5XA 1E0DA 2JFGA 2PQ5A 3F9AA 1BZHA 2ZN7A 4OHHA 1U24A 2FJMA 1NL9A 2CMBA 1WRMA 4NWGA 5LXQB 4R30A 3F9BA 2MBCA 1OHCA 5BX1A 3AWFA 2UAGA 4CVKA 2F6FA 1YGRA 3S3HA 3LJ8A 4S0GA 1LQFA 2PA5A 2B4PA 2CMCA 3QCDA 3RGOA 3D44A 2P6XA 2CM8A 2SHPA 1JBVA 3PYZA 2QDMA 4BUCA 2BZLA 1JBWA 2NTAA 3MOWA 2I6JA 3F99A 2NLKA 1ZZWA 4RDDA 5GTJA 2J17A 1T48A 4H1OA 1RXDA 2CM3A 1LARA 2PSZA 2CNFA 2VEVA 4RH5A 2I4GA 1OEOX 1EEHA 1YTSA 1ECVA 3S3KA 2G59A 2FJNA 1XBOA 1NWEA 5K25A 1NO6A 4YAAA 3ZM0A 1GG4A 2CFVA 1PXHA 4DGPA 5KAAA 1AAXA 3UAGA 4WTYA 2F71A 1J6UA 2VEXA 3I80A 5A5EA 1Q6JA 2AHSA 4C12A 2JJDA 3GXGA 3F81A 2CM2A 3F41A 2GCAA 2I1YA 2F70A 2PBNA 2H04A 3BLUA 2C46A 2AZRA 4CVMA 3RO1A 5EHRA 3QKQA 1U26A 3PS5A 4PVGA 1PTYA 1QZ0A 2GWOA 5A5FA 2OC3A 2I6MA 4RHGA 1YFOA 1ZCLA 1PA9A 2VTEA 5KA1A 4QBEA 1XXVA 1PYNA 2I5XA 2WJPA 1W7KA 2OOQA 3O3LA 2HY3A 3I36A 3QCFA 1YZ4A 2I75A 5MMZB 3ZM6A 1J4XA 4NYHA 4JBCA 1YGUA 3QCMA 4GE6A 5KA4A 5KA8A 3MVNA 3AWEA 2F6ZA 4D3RA 3NRSA 3QCZA 1FPRA 3O4UA 1Q6SA 5AWXA 2GP0A 1A5YA 3ZMPA 4GFUA 3EB1A 2WGPA 1T49A 2M3VA 2VEUA 1Q6TA 4RI4A 3MOZA 2NT7A 4KYQA 5J8RA 1OEVA 2NT2A 1GQQA 1G4WR 4ZN5A 1ONYA 2HC1A 4QAHA 3QCBA 3SMEA 3S4EA 1WAXA 3QCHA 3ZM1A 1YTNA 1C87A 2F6VA 3BLTA 4JMKA 1Q6NA 4HJPA 2E0TA 3ZMQA 3ZM2A 3ZM5A 2UUOA 1E8CA 4CVLA 1C88A 1RPMA 1LYVA 3GXHA 4JMJA 2AM1A 4NX8A 3QCIA 1FPZA 1R6HA 1SUGA 2CMAA 4NWFA 5I6VA 2HB1A 4QBWA 2UUPA 2ZMMA 1ZCKA 4GRZA 1FQ1A 3V0HA 5KADA 2QBQA 2Y96A 1ONZA 3BRHA 3HN7A 4OHLA 5IBMA 1PTUA 5M43A 1VHRA 1I57A 5KACA 3LK7A 1WCHA 1X24A 3EZZA 2I3RA 2QDCA 3RZ2A 1GFYA 1GWZA 1O5ZA 5K24A 5K9VA 1XRIA 4D3PA 2Y66A 2XPCA 2CNEA 1PA1A 2R0BA 4R0SA 2B4OA 3V0EA 1PTTA 2F6YA 2HNQA 2DXPA 3EAXA 2I4EA 2B49A 2OZ5A 3D1OA 2HXPA 2OUDA 2Y68A 1UAGA 5KA9A 2WTZA 1EENA 4Y2EA 2VEWA 1JLNA 4GWFA 3EU0A 4B04A 3D9CA 4DGXA 3S3EA 1NNYA 2I3UA 1L8KA 2HC2A 4OHDA 1C85A 2ESBA 5KA3A 5BUGA 1KAKA 1NZ7A 5K22A 2QDPA 3I7ZA 3RGQA 3H2XA 3ZM3A 2H4GA 2G6ZA 2VTDA 5K23A 2I42A 2Q47A 2YDUA 4RKKA 2B4SA 3V0DA 3QCEA 1G1HA 2BIJA 2J16B 3QCNA 3D1HA 3A5JA 1OEMX 5KA7A 1YPTA 2RF6A 1I9SA 2IMGA 1C86A 4BPCA 1ZC0A 4H34A 2F46A 2I6IA 3U96A 3B7OA 2QCJA 3MMJA 3O4TA 4QAPA 2NV5A 2CNIA 2GC5A 2C7SA 4ERCA 4BUBA 2Q05A 1G1GA 5BZXA 3V0JA 3V0FA 3O4SA 2CJZA 1NWLA 4HV4A 1OEUA 3SR9A 1BZCA 2HCMA 1Q1MA 4ICZA 1MKPA 1XM2A 1P3DA 3ZV2A 2GCBA 2F00A 3CWEA 3CM3A 5HDEA
chains in the Genus database with same CATH topology
1C83A 2VEYA 4MBBA 4WOHA 1G7GA 4WU3A 1Q6MA 1EEOA 2BGDA 1V3AA 3A5KA 2H02A 4D3QA 3D42A 2CNGA 2QCTA 4HJQA 4QUMA 2A8BA 2B4UA 2BGEA 3QCGA 5KA2A 1BZJA 1OHEA 2H03A 4KYRA 1P15A 4HRFA 1Q6PA 3QCCA 2I4HA 4I8NA 2HVLA 2CNHA 2Y2FA 3V0IA 1YWFA 4J51A 4YR8B 1PTVA 2HNPA 1G4US 4GFVA 4JNBA 3S4OA 4AZ1A 2P4DA 4ZI4A 1U25A 4ZRTA 4GE5A 1T4JA 4WU2A 3NMEA 4Y14A 2I6OA 1M3GA 1OHDA 2PT0A 2QBPA 4GE2A 1G1FA 5K9WA 1JF7A 2H4KA 4BJOA 2QBRA 4TVVA 1PH0A 3OLRA 1I9TA 2B3OA 4QUNA 2B07A 1YN9A 3QKPA 3V0GA 5EHPA 2QBSA 4OHEA 3OMHA 3QCJA 3QCLA 5BZZA 1YTWA 1L8GA 5KABA 4PYHA 4NNDA 2F6TA 3N0AA 4GRYA 3EMUA 4OHIA 1KAVA 1OESA 3QCKA 4RH9A 2PI7A 3M4UA 1D5RA 4R0TA 2J16A 3BM8A 2GJTA 3D1QA 1XXPA 5KA0A 2I6PA 4Z6BA 2H4VA 1OETA 2NZ6A 4GS0A 5IBSA 1G7FA 2BV5A 4KI9A 4IKCA 4RI5A 1C84A 2FH7A 1QXKA 2F6WA 3AWGA 3S3FA 2A3KA 2CM7A 2QEPA 3O5XA 2PQ5A 3F9AA 1BZHA 2ZN7A 4OHHA 1U24A 2FJMA 1NL9A 2CMBA 1WRMA 4NWGA 5LXQB 4R30A 3F9BA 2MBCA 1OHCA 5BX1A 3AWFA 2F6FA 1YGRA 3S3HA 3LJ8A 4S0GA 1LQFA 2PA5A 2B4PA 2CMCA 3QCDA 3RGOA 3D44A 2P6XA 2CM8A 2SHPA 2QDMA 2BZLA 2NTAA 3MOWA 2I6JA 3F99A 2NLKA 1ZZWA 4RDDA 5GTJA 2J17A 1T48A 4H1OA 1RXDA 2CM3A 1LARA 2PSZA 2CNFA 2VEVA 4RH5A 2I4GA 1OEOX 1YTSA 1ECVA 3S3KA 2G59A 2FJNA 1XBOA 1NWEA 5K25A 1NO6A 4YAAA 3ZM0A 2CFVA 1PXHA 4DGPA 5KAAA 1AAXA 4WTYA 2F71A 2VEXA 3I80A 1Q6JA 2AHSA 2JJDA 3GXGA 3F81A 2CM2A 3F41A 2I1YA 2F70A 2PBNA 2H04A 3BLUA 2C46A 2AZRA 3RO1A 5EHRA 3QKQA 1U26A 3PS5A 4PVGA 1PTYA 1QZ0A 2GWOA 2OC3A 2I6MA 4RHGA 1YFOA 1ZCLA 1PA9A 5KA1A 4QBEA 1XXVA 1PYNA 2I5XA 2OOQA 3O3LA 2HY3A 3I36A 3QCFA 1YZ4A 2I75A 5MMZB 1J4XA 4NYHA 4JBCA 1YGUA 3QCMA 4GE6A 5KA4A 5KA8A 3AWEA 2F6ZA 4D3RA 1FPRA 3O4UA 1Q6SA 5AWXA 2GP0A 1A5YA 3ZMPA 4GFUA 3EB1A 2WGPA 1T49A 2M3VA 2VEUA 1Q6TA 4RI4A 3MOZA 2NT7A 4KYQA 5J8RA 1OEVA 2NT2A 1G4WR 4ZN5A 1ONYA 2HC1A 4QAHA 3QCBA 3SMEA 3S4EA 1WAXA 3QCHA 3ZM1A 1YTNA 1C87A 2F6VA 3BLTA 4JMKA 1Q6NA 4HJPA 2E0TA 3ZMQA 3ZM2A 1C88A 1RPMA 1LYVA 3GXHA 4JMJA 4NX8A 3QCIA 1FPZA 1R6HA 1SUGA 2CMAA 4NWFA 5I6VA 2HB1A 4QBWA 2ZMMA 1ZCKA 4GRZA 1FQ1A 3V0HA 5KADA 2QBQA 2Y96A 1ONZA 3BRHA 4OHLA 5IBMA 1PTUA 5M43A 1VHRA 1I57A 5KACA 1WCHA 1X24A 3EZZA 2I3RA 2QDCA 3RZ2A 1GFYA 1GWZA 5K24A 5K9VA 1XRIA 4D3PA 2CNEA 1PA1A 2R0BA 4R0SA 2B4OA 3V0EA 1PTTA 2F6YA 2HNQA 2DXPA 3EAXA 2I4EA 2B49A 2OZ5A 3D1OA 2HXPA 2OUDA 5KA9A 4Y2EA 1EENA 2VEWA 1JLNA 4GWFA 3EU0A 4B04A 3D9CA 4DGXA 3S3EA 1NNYA 2I3UA 1L8KA 2HC2A 4OHDA 1C85A 2ESBA 5KA3A 5BUGA 1KAKA 1NZ7A 5K22A 2QDPA 3I7ZA 3RGQA 3H2XA 3ZM3A 2H4GA 2G6ZA 5K23A 2I42A 2Q47A 2YDUA 4RKKA 2B4SA 3V0DA 3QCEA 1G1HA 2BIJA 2J16B 3QCNA 3D1HA 3A5JA 1OEMX 5KA7A 1YPTA 2RF6A 1I9SA 2IMGA 1C86A 4BPCA 1ZC0A 4H34A 2F46A 2I6IA 3U96A 3B7OA 2QCJA 3MMJA 3O4TA 4QAPA 2NV5A 2CNIA 2C7SA 4ERCA 2Q05A 1G1GA 5BZXA 3V0JA 3V0FA 3O4SA 2CJZA 1NWLA 1OEUA 3SR9A 1BZCA 2HCMA 1Q1MA 4ICZA 1MKPA 1XM2A 3ZV2A 3CWEA 3CM3A 5HDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C83 A;  2VEY A;  4MBB A;  4WOH A;  1G7G A;  4WU3 A;  1Q6M A;  1EEO A;  2BGD A;  1V3A A;  3A5K A;  2H02 A;  4D3Q A;  3D42 A;  2CNG A;  2QCT A;  4HJQ A;  4QUM A;  2A8B A;  2B4U A;  2BGE A;  3QCG A;  5KA2 A;  1BZJ A;  1OHE A;  2H03 A;  4KYR A;  1P15 A;  4HRF A;  1Q6P A;  3QCC A;  2I4H A;  4I8N A;  2HVL A;  2CNH A;  2Y2F A;  3V0I A;  1YWF A;  4J51 A;  4YR8 B;  1PTV A;  2HNP A;  1G4U S;  4GFV A;  4JNB A;  3S4O A;  4AZ1 A;  2P4D A;  4ZI4 A;  1U25 A;  4ZRT A;  4GE5 A;  1T4J A;  4WU2 A;  3NME A;  4Y14 A;  2I6O A;  1M3G A;  1OHD A;  2PT0 A;  2QBP A;  4GE2 A;  1G1F A;  5K9W A;  1JF7 A;  2H4K A;  4BJO A;  2QBR A;  4TVV A;  1PH0 A;  3OLR A;  1I9T A;  2B3O A;  4QUN A;  2B07 A;  1YN9 A;  3QKP A;  3V0G A;  5EHP A;  2QBS A;  4OHE A;  3OMH A;  3QCJ A;  3QCL A;  5BZZ A;  1YTW A;  1L8G A;  5KAB A;  4PYH A;  4NND A;  2F6T A;  3N0A A;  4GRY A;  3EMU A;  4OHI A;  1KAV A;  1OES A;  3QCK A;  4RH9 A;  2PI7 A;  3M4U A;  1D5R A;  4R0T A;  2J16 A;  3BM8 A;  2GJT A;  3D1Q A;  1XXP A;  5KA0 A;  2I6P A;  4Z6B A;  2H4V A;  1OET A;  2NZ6 A;  4GS0 A;  5IBS A;  1G7F A;  2BV5 A;  4KI9 A;  4IKC A;  4RI5 A;  1C84 A;  2FH7 A;  1QXK A;  2F6W A;  3AWG A;  3S3F A;  2A3K A;  2CM7 A;  2QEP A;  3O5X A;  2PQ5 A;  3F9A A;  1BZH A;  2ZN7 A;  4OHH A;  1U24 A;  2FJM A;  1NL9 A;  2CMB A;  1WRM A;  4NWG A;  5LXQ B;  4R30 A;  3F9B A;  2MBC A;  1OHC A;  5BX1 A;  3AWF A;  2F6F A;  1YGR A;  3S3H A;  3LJ8 A;  4S0G A;  1LQF A;  2PA5 A;  2B4P A;  2CMC A;  3QCD A;  3RGO A;  3D44 A;  2P6X A;  2CM8 A;  2SHP A;  2QDM A;  2BZL A;  2NTA A;  3MOW A;  2I6J A;  3F99 A;  2NLK A;  1ZZW A;  4RDD A;  5GTJ A;  2J17 A;  1T48 A;  4H1O A;  1RXD A;  2CM3 A;  1LAR A;  2PSZ A;  2CNF A;  2VEV A;  4RH5 A;  2I4G A;  1OEO X;  1YTS A;  1ECV A;  3S3K A;  2G59 A;  2FJN A;  1XBO A;  1NWE A;  5K25 A;  1NO6 A;  4YAA A;  3ZM0 A;  2CFV A;  1PXH A;  4DGP A;  5KAA A;  1AAX A;  4WTY A;  2F71 A;  2VEX A;  3I80 A;  1Q6J A;  2AHS A;  2JJD A;  3GXG A;  3F81 A;  2CM2 A;  3F41 A;  2I1Y A;  2F70 A;  2PBN A;  2H04 A;  3BLU A;  2C46 A;  2AZR A;  3RO1 A;  5EHR A;  3QKQ A;  1U26 A;  3PS5 A;  4PVG A;  1PTY A;  1QZ0 A;  2GWO A;  2OC3 A;  2I6M A;  4RHG A;  1YFO A;  1ZCL A;  1PA9 A;  5KA1 A;  4QBE A;  1XXV A;  1PYN A;  2I5X A;  2OOQ A;  3O3L A;  2HY3 A;  3I36 A;  3QCF A;  1YZ4 A;  2I75 A;  5MMZ B;  1J4X A;  4NYH A;  4JBC A;  1YGU A;  3QCM A;  4GE6 A;  5KA4 A;  5KA8 A;  3AWE A;  2F6Z A;  4D3R A;  1FPR A;  3O4U A;  1Q6S A;  5AWX A;  2GP0 A;  1A5Y A;  3ZMP A;  4GFU A;  3EB1 A;  2WGP A;  1T49 A;  2M3V A;  2VEU A;  1Q6T A;  4RI4 A;  3MOZ A;  2NT7 A;  4KYQ A;  5J8R A;  1OEV A;  2NT2 A;  1G4W R;  4ZN5 A;  1ONY A;  2HC1 A;  4QAH A;  3QCB A;  3SME A;  3S4E A;  1WAX A;  3QCH A;  3ZM1 A;  1YTN A;  1C87 A;  2F6V A;  3BLT A;  4JMK A;  1Q6N A;  4HJP A;  2E0T A;  3ZMQ A;  3ZM2 A;  1C88 A;  1RPM A;  1LYV A;  3GXH A;  4JMJ A;  4NX8 A;  3QCI A;  1FPZ A;  1R6H A;  1SUG A;  2CMA A;  4NWF A;  5I6V A;  2HB1 A;  4QBW A;  2ZMM A;  1ZCK A;  4GRZ A;  1FQ1 A;  3V0H A;  5KAD A;  2QBQ A;  2Y96 A;  1ONZ A;  3BRH A;  4OHL A;  5IBM A;  1PTU A;  5M43 A;  1VHR A;  1I57 A;  5KAC A;  1WCH A;  1X24 A;  3EZZ A;  2I3R A;  2QDC A;  3RZ2 A;  1GFY A;  1GWZ A;  5K24 A;  5K9V A;  1XRI A;  4D3P A;  2CNE A;  1PA1 A;  2R0B A;  4R0S A;  2B4O A;  3V0E A;  1PTT A;  2F6Y A;  2HNQ A;  2DXP A;  3EAX A;  2I4E A;  2B49 A;  2OZ5 A;  3D1O A;  2HXP A;  2OUD A;  5KA9 A;  4Y2E A;  1EEN A;  2VEW A;  1JLN A;  4GWF A;  3EU0 A;  4B04 A;  3D9C A;  4DGX A;  3S3E A;  1NNY A;  2I3U A;  1L8K A;  2HC2 A;  4OHD A;  1C85 A;  2ESB A;  5KA3 A;  5BUG A;  1KAK A;  1NZ7 A;  5K22 A;  2QDP A;  3I7Z A;  3RGQ A;  3H2X A;  3ZM3 A;  2H4G A;  2G6Z A;  5K23 A;  2I42 A;  2Q47 A;  2YDU A;  4RKK A;  2B4S A;  3V0D A;  3QCE A;  1G1H A;  2BIJ A;  2J16 B;  3QCN A;  3D1H A;  3A5J A;  1OEM X;  5KA7 A;  1YPT A;  2RF6 A;  1I9S A;  2IMG A;  1C86 A;  4BPC A;  1ZC0 A;  4H34 A;  2F46 A;  2I6I A;  3U96 A;  3B7O A;  2QCJ A;  3MMJ A;  3O4T A;  4QAP A;  2NV5 A;  2CNI A;  2C7S A;  4ERC A;  2Q05 A;  1G1G A;  5BZX A;  3V0J A;  3V0F A;  3O4S A;  2CJZ A;  1NWL A;  1OEU A;  3SR9 A;  1BZC A;  2HCM A;  1Q1M A;  4ICZ A;  1MKP A;  1XM2 A;  3ZV2 A;  3CWE A;  3CM3 A;  5HDE A; 
#chains in the Genus database with same CATH topology
 1C83 A;  2VEY A;  4MBB A;  4WOH A;  1G7G A;  4QDI A;  4WU3 A;  1Q6M A;  1EEO A;  2BGD A;  1V3A A;  3A5K A;  2H02 A;  4D3Q A;  3D42 A;  2CNG A;  2QCT A;  4HJQ A;  4QUM A;  2A8B A;  2B4U A;  2BGE A;  3QCG A;  5KA2 A;  1BZJ A;  1OHE A;  2H03 A;  2JFH A;  1P15 A;  4KYR A;  4HRF A;  1Q6P A;  4ZIY A;  3QCC A;  4QF5 A;  2I4H A;  2X5O A;  4I8N A;  2HVL A;  2CNH A;  2Y2F A;  3V0I A;  1YWF A;  4J51 A;  2Y1O A;  4YR8 B;  1PTV A;  2HNP A;  4C13 A;  1G4U S;  4GFV A;  4JNB A;  3S4O A;  2JFF A;  4AZ1 A;  2P4D A;  4ZI4 A;  1U25 A;  4ZRT A;  4GE5 A;  1T4J A;  4WU2 A;  3NME A;  4Y14 A;  2I6O A;  1M3G A;  1GQY A;  2Y67 A;  1OHD A;  2PT0 A;  2QBP A;  4GE2 A;  1G1F A;  5K9W A;  1JF7 A;  2H4K A;  1W78 A;  2AM2 A;  2QBR A;  4TVV A;  4BJO A;  1PH0 A;  3OLR A;  1I9T A;  2B3O A;  4QUN A;  2VOR A;  2B07 A;  1YN9 A;  3QKP A;  3V0G A;  2VOS A;  2QBS A;  4OHE A;  5EHP A;  3OMH A;  3QCJ A;  3QCL A;  5BZZ A;  1YTW A;  1L8G A;  5KAB A;  4PYH A;  4NND A;  1FGS A;  2F6T A;  3N0A A;  4GRY A;  3EMU A;  4OHI A;  1KAV A;  1OES A;  3QCK A;  4RH9 A;  2PI7 A;  3M4U A;  1D5R A;  4R0T A;  2J16 A;  3BM8 A;  3N2A A;  2GJT A;  3D1Q A;  1XXP A;  2GC6 A;  5KA0 A;  2I6P A;  4Z6B A;  3ZL8 A;  1P31 A;  2H4V A;  4UAG A;  2XJA A;  1OET A;  2NZ6 A;  4GS0 A;  5IBS A;  1G7F A;  2BV5 A;  4KI9 A;  4IKC A;  4RI5 A;  1C84 A;  2FH7 A;  1QXK A;  2F6W A;  3AWG A;  3S3F A;  2A3K A;  2CM7 A;  2QEP A;  3O5X A;  1E0D A;  2JFG A;  2PQ5 A;  3F9A A;  1BZH A;  2ZN7 A;  4OHH A;  1U24 A;  2FJM A;  1NL9 A;  2CMB A;  1WRM A;  4NWG A;  5LXQ B;  4R30 A;  3F9B A;  2MBC A;  1OHC A;  5BX1 A;  3AWF A;  2UAG A;  4CVK A;  2F6F A;  1YGR A;  3S3H A;  3LJ8 A;  4S0G A;  1LQF A;  2PA5 A;  2B4P A;  2CMC A;  3QCD A;  3RGO A;  3D44 A;  2P6X A;  2CM8 A;  2SHP A;  1JBV A;  3PYZ A;  2QDM A;  4BUC A;  2BZL A;  1JBW A;  2NTA A;  3MOW A;  2I6J A;  3F99 A;  2NLK A;  1ZZW A;  4RDD A;  5GTJ A;  2J17 A;  1T48 A;  4H1O A;  1RXD A;  2CM3 A;  1LAR A;  2PSZ A;  2CNF A;  2VEV A;  4RH5 A;  2I4G A;  1OEO X;  1EEH A;  1YTS A;  1ECV A;  3S3K A;  2G59 A;  2FJN A;  1XBO A;  1NWE A;  5K25 A;  1NO6 A;  4YAA A;  3ZM0 A;  1GG4 A;  2CFV A;  1PXH A;  4DGP A;  5KAA A;  1AAX A;  3UAG A;  4WTY A;  2F71 A;  1J6U A;  2VEX A;  3I80 A;  5A5E A;  1Q6J A;  2AHS A;  4C12 A;  2JJD A;  3GXG A;  3F81 A;  2CM2 A;  3F41 A;  2GCA A;  2I1Y A;  2F70 A;  2PBN A;  2H04 A;  3BLU A;  2C46 A;  2AZR A;  4CVM A;  3RO1 A;  5EHR A;  3QKQ A;  1U26 A;  3PS5 A;  4PVG A;  1PTY A;  1QZ0 A;  2GWO A;  5A5F A;  2OC3 A;  2I6M A;  4RHG A;  1YFO A;  1ZCL A;  1PA9 A;  2VTE A;  5KA1 A;  4QBE A;  1XXV A;  1PYN A;  2I5X A;  2WJP A;  1W7K A;  2OOQ A;  3O3L A;  2HY3 A;  3I36 A;  3QCF A;  1YZ4 A;  2I75 A;  5MMZ B;  3ZM6 A;  1J4X A;  4NYH A;  4JBC A;  1YGU A;  3QCM A;  4GE6 A;  5KA4 A;  5KA8 A;  3MVN A;  3AWE A;  2F6Z A;  4D3R A;  3NRS A;  3QCZ A;  1FPR A;  3O4U A;  1Q6S A;  5AWX A;  2GP0 A;  1A5Y A;  3ZMP A;  4GFU A;  3EB1 A;  2WGP A;  1T49 A;  2M3V A;  2VEU A;  1Q6T A;  4RI4 A;  3MOZ A;  2NT7 A;  4KYQ A;  5J8R A;  1OEV A;  2NT2 A;  1GQQ A;  1G4W R;  4ZN5 A;  1ONY A;  2HC1 A;  4QAH A;  3QCB A;  3SME A;  3S4E A;  1WAX A;  3QCH A;  3ZM1 A;  1YTN A;  1C87 A;  2F6V A;  3BLT A;  4JMK A;  1Q6N A;  4HJP A;  2E0T A;  3ZMQ A;  3ZM2 A;  3ZM5 A;  2UUO A;  1E8C A;  4CVL A;  1C88 A;  1RPM A;  1LYV A;  3GXH A;  4JMJ A;  2AM1 A;  4NX8 A;  3QCI A;  1FPZ A;  1R6H A;  1SUG A;  2CMA A;  4NWF A;  5I6V A;  2HB1 A;  4QBW A;  2UUP A;  2ZMM A;  1ZCK A;  4GRZ A;  1FQ1 A;  3V0H A;  5KAD A;  2QBQ A;  2Y96 A;  1ONZ A;  3BRH A;  3HN7 A;  4OHL A;  5IBM A;  1PTU A;  5M43 A;  1VHR A;  1I57 A;  5KAC A;  3LK7 A;  1WCH A;  1X24 A;  3EZZ A;  2I3R A;  2QDC A;  3RZ2 A;  1GFY A;  1GWZ A;  1O5Z A;  5K24 A;  5K9V A;  1XRI A;  4D3P A;  2Y66 A;  2XPC A;  2CNE A;  1PA1 A;  2R0B A;  4R0S A;  2B4O A;  3V0E A;  1PTT A;  2F6Y A;  2HNQ A;  2DXP A;  3EAX A;  2I4E A;  2B49 A;  2OZ5 A;  3D1O A;  2HXP A;  2OUD A;  2Y68 A;  1UAG A;  5KA9 A;  2WTZ A;  1EEN A;  4Y2E A;  2VEW A;  1JLN A;  4GWF A;  3EU0 A;  4B04 A;  3D9C A;  4DGX A;  3S3E A;  1NNY A;  2I3U A;  1L8K A;  2HC2 A;  4OHD A;  1C85 A;  2ESB A;  5KA3 A;  5BUG A;  1KAK A;  1NZ7 A;  5K22 A;  2QDP A;  3I7Z A;  3RGQ A;  3H2X A;  3ZM3 A;  2H4G A;  2G6Z A;  2VTD A;  5K23 A;  2I42 A;  2Q47 A;  2YDU A;  4RKK A;  2B4S A;  3V0D A;  3QCE A;  1G1H A;  2BIJ A;  2J16 B;  3QCN A;  3D1H A;  3A5J A;  1OEM X;  5KA7 A;  1YPT A;  2RF6 A;  1I9S A;  2IMG A;  1C86 A;  4BPC A;  1ZC0 A;  4H34 A;  2F46 A;  2I6I A;  3U96 A;  3B7O A;  2QCJ A;  3MMJ A;  3O4T A;  4QAP A;  2NV5 A;  2CNI A;  2GC5 A;  2C7S A;  4ERC A;  4BUB A;  2Q05 A;  1G1G A;  5BZX A;  3V0J A;  3V0F A;  3O4S A;  2CJZ A;  1NWL A;  4HV4 A;  1OEU A;  3SR9 A;  1BZC A;  2HCM A;  1Q1M A;  4ICZ A;  1MKP A;  1XM2 A;  1P3D A;  3ZV2 A;  2GCB A;  2F00 A;  3CWE A;  3CM3 A;  5HDE A; 
#chains in the Genus database with same CATH homology
 1C83 A;  2VEY A;  4MBB A;  4WOH A;  1G7G A;  4WU3 A;  1Q6M A;  1EEO A;  2BGD A;  1V3A A;  3A5K A;  2H02 A;  4D3Q A;  3D42 A;  2CNG A;  2QCT A;  4HJQ A;  4QUM A;  2A8B A;  2B4U A;  2BGE A;  3QCG A;  5KA2 A;  1BZJ A;  1OHE A;  2H03 A;  4KYR A;  1P15 A;  4HRF A;  1Q6P A;  3QCC A;  2I4H A;  4I8N A;  2HVL A;  2CNH A;  2Y2F A;  3V0I A;  1YWF A;  4J51 A;  4YR8 B;  1PTV A;  2HNP A;  1G4U S;  4GFV A;  4JNB A;  3S4O A;  4AZ1 A;  2P4D A;  4ZI4 A;  1U25 A;  4ZRT A;  4GE5 A;  1T4J A;  4WU2 A;  3NME A;  4Y14 A;  2I6O A;  1M3G A;  1OHD A;  2PT0 A;  2QBP A;  4GE2 A;  1G1F A;  5K9W A;  1JF7 A;  2H4K A;  4BJO A;  2QBR A;  4TVV A;  1PH0 A;  3OLR A;  1I9T A;  2B3O A;  4QUN A;  2B07 A;  1YN9 A;  3QKP A;  3V0G A;  5EHP A;  2QBS A;  4OHE A;  3OMH A;  3QCJ A;  3QCL A;  5BZZ A;  1YTW A;  1L8G A;  5KAB A;  4PYH A;  4NND A;  2F6T A;  3N0A A;  4GRY A;  3EMU A;  4OHI A;  1KAV A;  1OES A;  3QCK A;  4RH9 A;  2PI7 A;  3M4U A;  1D5R A;  4R0T A;  2J16 A;  3BM8 A;  2GJT A;  3D1Q A;  1XXP A;  5KA0 A;  2I6P A;  4Z6B A;  2H4V A;  1OET A;  2NZ6 A;  4GS0 A;  5IBS A;  1G7F A;  2BV5 A;  4KI9 A;  4IKC A;  4RI5 A;  1C84 A;  2FH7 A;  1QXK A;  2F6W A;  3AWG A;  3S3F A;  2A3K A;  2CM7 A;  2QEP A;  3O5X A;  2PQ5 A;  3F9A A;  1BZH A;  2ZN7 A;  4OHH A;  1U24 A;  2FJM A;  1NL9 A;  2CMB A;  1WRM A;  4NWG A;  5LXQ B;  4R30 A;  3F9B A;  2MBC A;  1OHC A;  5BX1 A;  3AWF A;  2F6F A;  1YGR A;  3S3H A;  3LJ8 A;  4S0G A;  1LQF A;  2PA5 A;  2B4P A;  2CMC A;  3QCD A;  3RGO A;  3D44 A;  2P6X A;  2CM8 A;  2SHP A;  2QDM A;  2BZL A;  2NTA A;  3MOW A;  2I6J A;  3F99 A;  2NLK A;  1ZZW A;  4RDD A;  5GTJ A;  2J17 A;  1T48 A;  4H1O A;  1RXD A;  2CM3 A;  1LAR A;  2PSZ A;  2CNF A;  2VEV A;  4RH5 A;  2I4G A;  1OEO X;  1YTS A;  1ECV A;  3S3K A;  2G59 A;  2FJN A;  1XBO A;  1NWE A;  5K25 A;  1NO6 A;  4YAA A;  3ZM0 A;  2CFV A;  1PXH A;  4DGP A;  5KAA A;  1AAX A;  4WTY A;  2F71 A;  2VEX A;  3I80 A;  1Q6J A;  2AHS A;  2JJD A;  3GXG A;  3F81 A;  2CM2 A;  3F41 A;  2I1Y A;  2F70 A;  2PBN A;  2H04 A;  3BLU A;  2C46 A;  2AZR A;  3RO1 A;  5EHR A;  3QKQ A;  1U26 A;  3PS5 A;  4PVG A;  1PTY A;  1QZ0 A;  2GWO A;  2OC3 A;  2I6M A;  4RHG A;  1YFO A;  1ZCL A;  1PA9 A;  5KA1 A;  4QBE A;  1XXV A;  1PYN A;  2I5X A;  2OOQ A;  3O3L A;  2HY3 A;  3I36 A;  3QCF A;  1YZ4 A;  2I75 A;  5MMZ B;  1J4X A;  4NYH A;  4JBC A;  1YGU A;  3QCM A;  4GE6 A;  5KA4 A;  5KA8 A;  3AWE A;  2F6Z A;  4D3R A;  1FPR A;  3O4U A;  1Q6S A;  5AWX A;  2GP0 A;  1A5Y A;  3ZMP A;  4GFU A;  3EB1 A;  2WGP A;  1T49 A;  2M3V A;  2VEU A;  1Q6T A;  4RI4 A;  3MOZ A;  2NT7 A;  4KYQ A;  5J8R A;  1OEV A;  2NT2 A;  1G4W R;  4ZN5 A;  1ONY A;  2HC1 A;  4QAH A;  3QCB A;  3SME A;  3S4E A;  1WAX A;  3QCH A;  3ZM1 A;  1YTN A;  1C87 A;  2F6V A;  3BLT A;  4JMK A;  1Q6N A;  4HJP A;  2E0T A;  3ZMQ A;  3ZM2 A;  1C88 A;  1RPM A;  1LYV A;  3GXH A;  4JMJ A;  4NX8 A;  3QCI A;  1FPZ A;  1R6H A;  1SUG A;  2CMA A;  4NWF A;  5I6V A;  2HB1 A;  4QBW A;  2ZMM A;  1ZCK A;  4GRZ A;  1FQ1 A;  3V0H A;  5KAD A;  2QBQ A;  2Y96 A;  1ONZ A;  3BRH A;  4OHL A;  5IBM A;  1PTU A;  5M43 A;  1VHR A;  1I57 A;  5KAC A;  1WCH A;  1X24 A;  3EZZ A;  2I3R A;  2QDC A;  3RZ2 A;  1GFY A;  1GWZ A;  5K24 A;  5K9V A;  1XRI A;  4D3P A;  2CNE A;  1PA1 A;  2R0B A;  4R0S A;  2B4O A;  3V0E A;  1PTT A;  2F6Y A;  2HNQ A;  2DXP A;  3EAX A;  2I4E A;  2B49 A;  2OZ5 A;  3D1O A;  2HXP A;  2OUD A;  5KA9 A;  4Y2E A;  1EEN A;  2VEW A;  1JLN A;  4GWF A;  3EU0 A;  4B04 A;  3D9C A;  4DGX A;  3S3E A;  1NNY A;  2I3U A;  1L8K A;  2HC2 A;  4OHD A;  1C85 A;  2ESB A;  5KA3 A;  5BUG A;  1KAK A;  1NZ7 A;  5K22 A;  2QDP A;  3I7Z A;  3RGQ A;  3H2X A;  3ZM3 A;  2H4G A;  2G6Z A;  5K23 A;  2I42 A;  2Q47 A;  2YDU A;  4RKK A;  2B4S A;  3V0D A;  3QCE A;  1G1H A;  2BIJ A;  2J16 B;  3QCN A;  3D1H A;  3A5J A;  1OEM X;  5KA7 A;  1YPT A;  2RF6 A;  1I9S A;  2IMG A;  1C86 A;  4BPC A;  1ZC0 A;  4H34 A;  2F46 A;  2I6I A;  3U96 A;  3B7O A;  2QCJ A;  3MMJ A;  3O4T A;  4QAP A;  2NV5 A;  2CNI A;  2C7S A;  4ERC A;  2Q05 A;  1G1G A;  5BZX A;  3V0J A;  3V0F A;  3O4S A;  2CJZ A;  1NWL A;  1OEU A;  3SR9 A;  1BZC A;  2HCM A;  1Q1M A;  4ICZ A;  1MKP A;  1XM2 A;  3ZV2 A;  3CWE A;  3CM3 A;  5HDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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