2H02A

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
290
structure length
278
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein tyrosine phosphatase, receptor type, B,
total genus 98
structure length 278
sequence length 290
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2h02A00
3RGOA 1OEMX 2AHSA 4WOHA 2I4GA 2HXPA 2J17A 4ZI4A 4J51A 3V0GA 1L8GA 4OHHA 2FJMA 2NTAA 3F9AA 2BGEA 3RO1A 1G4US 5KABA 2I1YA 2I6MA 4IKCA 3QKQA 1PTYA 3NMEA 3ZM1A 1GWZA 2HNQA 4AZ1A 5I6VA 1NNYA 3F81A 4GE2A 5EHPA 4ZN5A 2I5XA 2I6OA 2FH7A 2F6ZA 1YWFA 3OLRA 4RI4A 2F46A 2H4KA 3V0EA 4RDDA 2PSZA 1PYNA 5HDEA 3RZ2A 4NX8A 2I4EA 1U25A 2I3UA 3AWGA 1C87A 2B4OA 1LARA 3QKPA 1RXDA 3ZMQA 1C88A 1OEUA 3A5JA 2J16B 3A5KA 2P4DA 1NL9A 3EZZA 2QCTA 4NWFA 4RH9A 2GP0A 3O5XA 1ZZWA 1YTNA 1PTVA 1XXPA 1ZCLA 2NZ6A 1C86A 1P15A 4GRZA 1PTUA 2PBNA 2I42A 2CNGA 5BUGA 5KA9A 3O4SA 4D3PA 5IBMA 3F9BA 1KAVA 2VEYA 2B4SA 3V0DA 3BM8A 1BZJA 1OEVA 2CM2A 3ZM3A 2QDMA 3PS5A 3LJ8A 2M3VA 1D5RA 2BGDA 3D1QA 2HNPA 4Y2EA 1Q6MA 3S3FA 2HY3A 3ZV2A 2C46A 2QDCA 1ONYA 1YGRA 1X24A 3CM3A 4I8NA 4HJPA 2BV5A 4QAPA 1RPMA 3GXHA 3QCGA 4R0SA 3GXGA 2FJNA 1XXVA 3V0HA 3QCHA 2C7SA 3ZM2A 4DGPA 4YAAA 2VEWA 2PI7A 2F6YA 1YN9A 5KA1A 4Z6BA 2HC2A 2BZLA 1EENA 1Q1MA 1QXKA 1OHCA 5KA3A 4WU2A 3M4UA 3SMEA 2P6XA 4GFVA 1G7GA 4H34A 4GWFA 1YZ4A 3SR9A 1ONZA 5EHRA 2OC3A 5K22A 3CWEA 2F6FA 2Y96A 2VEUA 3BRHA 2DXPA 1PXHA 1G4WR 1YPTA 3QCFA 5K25A 1C85A 2GWOA 4Y14A 2BIJA 4HRFA 5K23A 3D42A 2OOQA 4GE5A 2CMBA 2MBCA 2H4GA 1SUGA 2G6ZA 3AWFA 4QUNA 3QCIA 3QCEA 4NNDA 3V0JA 3S3KA 5M43A 5KA7A 4NWGA 4PVGA 2PQ5A 3RGQA 4JMJA 5KAAA 1C83A 1T48A 2CMCA 5GTJA 2ZMMA 4R0TA 2CNHA 3EAXA 3QCDA 5K9VA 1YTSA 2E0TA 2CMAA 2I4HA 2QBQA 4WTYA 1YGUA 2QEPA 2F6TA 1OHEA 2B49A 3V0IA 3QCKA 3EB1A 4TVVA 2I6IA 3QCNA 1G1GA 1G1HA 1G1FA 3B7OA 1M3GA 1NWEA 5KA2A 4QAHA 2CM3A 1U26A 3O3LA 3QCJA 3I80A 4KYQA 1XM2A 1AAXA 2J16A 3MMJA 1PA1A 2Q05A 2I75A 3MOWA 1PTTA 5KADA 3I36A 4JBCA 2CM8A 4GE6A 4KI9A 5AWXA 2I3RA 2CNFA 4HJQA 2I6JA 2HCMA 2ESBA 3V0FA 2H4VA 4DGXA 2Y2FA 3OMHA 1PH0A 2F70A 2NT7A 3QCBA 1Q6PA 1LQFA 1FPRA 3D1OA 2NT2A 2VEXA 4RI5A 2H04A 1MKPA 2QBRA 3D1HA 1LYVA 3ZM0A 3S4EA 2RF6A 3I7ZA 4OHEA 1GFYA 4ZRTA 3AWEA 3BLUA 1FQ1A 2CFVA 1NZ7A 2WGPA 4D3QA 5IBSA 4NYHA 2B4PA 4R30A 2I6PA 1U24A 3O4TA 1G7FA 4GFUA 3ZMPA 1QZ0A 5J8RA 1T4JA 4H1OA 1WCHA 5KA0A 2HC1A 2OUDA 3QCMA 1ZCKA 1L8KA 2B4UA 3S3HA 4JMKA 5KACA 2F6WA 1WRMA 2CJZA 2NV5A 2H02A 1BZHA 2B07A 5K9WA 1ZC0A 3F41A 1ECVA 1R6HA 2SHPA 4MBBA 4QBEA 1WAXA 1Q6JA 1FPZA 2PA5A 2HB1A 4D3RA 2A8BA 4RH5A 4PYHA 2JJDA 4WU3A 3S3EA 1A5YA 5K24A 1T49A 1EEOA 4KYRA 2GJTA 1VHRA 1Q6TA 5KA4A 2F6VA 3EU0A 3D44A 5BX1A 5LXQB 1JF7A 3N0AA 1YTWA 3D9CA 3U96A 2PT0A 1YFOA 1J4XA 5MMZB 2A3KA 4BPCA 1I57A 4GS0A 1XRIA 2AZRA 1C84A 3F99A 2F71A 3BLTA 4ICZA 2QBSA 2HVLA 1OETA 4GRYA 4QBWA 4RHGA 1KAKA 3H2XA 5BZZA 1V3AA 4B04A 4BJOA 1JLNA 2CNEA 4S0GA 1Q6NA 2CM7A 1I9SA 1OHDA 2OZ5A 2R0BA 4QUMA 4OHDA 2CNIA 4OHIA 2NLKA 4ERCA 4RKKA 1OESA 1XBOA 2QDPA 3EMUA 2YDUA 4OHLA 1NWLA 3MOZA 1NO6A 3QCCA 2H03A 5BZXA 2Q47A 3S4OA 1OEOX 5KA8A 3QCLA 2IMGA 2QBPA 2QCJA 2VEVA 4JNBA 2ZN7A 2B3OA 1Q6SA 2G59A 4YR8B 1PA9A 1BZCA 1I9TA 3O4UA
chains in the Genus database with same CATH superfamily
3RGOA 1GQYA 1OEMX 3LK7A 2AHSA 4WOHA 2I4GA 1JBWA 2HXPA 2J17A 4ZI4A 4J51A 3V0GA 1L8GA 4OHHA 2FJMA 1FGSA 2NTAA 3F9AA 2BGEA 3HN7A 3RO1A 1G4US 5KABA 2I1YA 2I6MA 4IKCA 3QKQA 1PTYA 3NMEA 3ZM1A 1GWZA 2HNQA 4AZ1A 5I6VA 1NNYA 3F81A 4GE2A 5EHPA 4ZN5A 2I5XA 2I6OA 2AM1A 2FH7A 2WTZA 3ZM5A 2F6ZA 1YWFA 3OLRA 4RI4A 1W7KA 2F46A 2H4KA 3V0EA 4RDDA 2PSZA 1PYNA 5HDEA 3RZ2A 4NX8A 2I4EA 1U25A 2I3UA 3N2AA 3AWGA 1EEHA 1W78A 1C87A 2XJAA 2B4OA 1LARA 3QKPA 1RXDA 3ZMQA 1C88A 1OEUA 3A5JA 4BUCA 2VOSA 2J16B 3A5KA 2P4DA 1O5ZA 1NL9A 3EZZA 2QCTA 4NWFA 4RH9A 3UAGA 2GP0A 4HV4A 2UAGA 3O5XA 1ZZWA 2WJPA 1YTNA 4QF5A 1PTVA 1XXPA 1ZCLA 2NZ6A 1C86A 2Y67A 1P15A 4GRZA 1PTUA 2PBNA 2I42A 2CNGA 5BUGA 5KA9A 3O4SA 4D3PA 5IBMA 3F9BA 1KAVA 2VEYA 2B4SA 3V0DA 3BM8A 4ZIYA 1BZJA 1OEVA 2CM2A 3ZM3A 2QDMA 3PS5A 3LJ8A 2M3VA 4CVMA 1D5RA 2BGDA 3D1QA 2HNPA 4Y2EA 1Q6MA 2VORA 3S3FA 2HY3A 3ZV2A 2C46A 2QDCA 1ONYA 1YGRA 2Y66A 1X24A 2UUPA 3CM3A 4I8NA 4HJPA 2BV5A 4QAPA 1RPMA 3GXHA 3QCGA 4R0SA 2AM2A 3GXGA 2FJNA 1XXVA 3V0HA 3QCHA 2C7SA 3ZM2A 4DGPA 4YAAA 2VEWA 2PI7A 2F6YA 1YN9A 1J6UA 5KA1A 4Z6BA 2HC2A 2BZLA 1EENA 5A5FA 1Q1MA 1QXKA 1OHCA 5KA3A 4WU2A 3M4UA 3SMEA 2JFGA 2P6XA 2UUOA 1G7GA 4GFVA 4H34A 4GWFA 1YZ4A 3SR9A 4CVKA 1ONZA 5EHRA 4C13A 2F00A 2OC3A 5K22A 3CWEA 2F6FA 2Y96A 2VEUA 1P3DA 3BRHA 2DXPA 1PXHA 1G4WR 1YPTA 3QCFA 5K25A 1C85A 2GWOA 4Y14A 2BIJA 4HRFA 1GQQA 3D42A 5K23A 2OOQA 4GE5A 2CMBA 2MBCA 2H4GA 1SUGA 2G6ZA 3AWFA 4QUNA 3QCIA 3QCEA 4NNDA 3V0JA 3S3KA 5M43A 5KA7A 4NWGA 4PVGA 2PQ5A 3RGQA 4JMJA 5KAAA 1C83A 1T48A 2CMCA 5GTJA 2JFFA 2ZMMA 2CNHA 3EAXA 4R0TA 3QCDA 5A5EA 5K9VA 2Y1OA 1YTSA 2E0TA 2CMAA 2I4HA 2QBQA 4WTYA 1YGUA 2QEPA 3ZM6A 2F6TA 1OHEA 2B49A 3V0IA 3QCKA 3EB1A 4TVVA 2I6IA 3ZL8A 3QCNA 1G1GA 1G1HA 1G1FA 3B7OA 1M3GA 1NWEA 5KA2A 4QAHA 2CM3A 1U26A 3O3LA 3QCJA 3I80A 4KYQA 1XM2A 1AAXA 2J16A 3MMJA 1PA1A 2VTDA 2Q05A 2I75A 2XPCA 3MOWA 1PTTA 2GCAA 5KADA 3I36A 4JBCA 2CM8A 4GE6A 4KI9A 5AWXA 2I3RA 2CNFA 4HJQA 2I6JA 1UAGA 2HCMA 2ESBA 3V0FA 2H4VA 4DGXA 2JFHA 4UAGA 2Y2FA 3OMHA 1PH0A 2F70A 2NT7A 3QCBA 1LQFA 1FPRA 1Q6PA 3D1OA 3MVNA 2NT2A 2VEXA 4RI5A 3QCZA 2GC6A 2H04A 1E8CA 1MKPA 2QBRA 3D1HA 1LYVA 3ZM0A 3S4EA 2RF6A 3I7ZA 2GCBA 4QDIA 4OHEA 1GFYA 4ZRTA 3AWEA 4C12A 3BLUA 1FQ1A 2CFVA 1NZ7A 2WGPA 4D3QA 5IBSA 4NYHA 2B4PA 4R30A 2I6PA 1U24A 3O4TA 4CVLA 1G7FA 4GFUA 3ZMPA 1QZ0A 5J8RA 1T4JA 1JBVA 4H1OA 1WCHA 5KA0A 2HC1A 2OUDA 3QCMA 1ZCKA 3NRSA 1L8KA 2B4UA 3S3HA 4JMKA 5KACA 2F6WA 1WRMA 2VTEA 2CJZA 2NV5A 2H02A 1BZHA 2B07A 5K9WA 1ZC0A 3F41A 1ECVA 1R6HA 2SHPA 4MBBA 4QBEA 1WAXA 1Q6JA 1FPZA 2PA5A 2HB1A 4D3RA 2A8BA 4RH5A 4PYHA 2JJDA 4WU3A 3S3EA 1A5YA 5K24A 1T49A 1EEOA 4KYRA 2GJTA 1VHRA 1Q6TA 5KA4A 2X5OA 2F6VA 3EU0A 3D44A 5BX1A 5LXQB 2GC5A 1JF7A 3N0AA 1YTWA 3D9CA 1P31A 2PT0A 3U96A 1YFOA 1J4XA 5MMZB 2A3KA 4BPCA 1I57A 4GS0A 2Y68A 3PYZA 1XRIA 2AZRA 1C84A 3F99A 2F71A 3BLTA 4ICZA 2QBSA 2HVLA 1OETA 4GRYA 4QBWA 4RHGA 1KAKA 3H2XA 5BZZA 1V3AA 4B04A 4BJOA 1JLNA 2CNEA 4S0GA 1Q6NA 1GG4A 2CM7A 1I9SA 1OHDA 2OZ5A 2R0BA 4QUMA 4OHDA 2CNIA 4OHIA 2NLKA 4ERCA 4RKKA 1OESA 1XBOA 2QDPA 3EMUA 2YDUA 4OHLA 1NWLA 3MOZA 1NO6A 3QCCA 2H03A 5BZXA 2Q47A 3S4OA 1OEOX 5KA8A 3QCLA 2IMGA 2QBPA 2QCJA 2VEVA 4JNBA 4BUBA 2ZN7A 2B3OA 1Q6SA 2G59A 4YR8B 1PA9A 1E0DA 1BZCA 1I9TA 3O4UA
chains in the Genus database with same CATH topology
3RGOA 1OEMX 2AHSA 4WOHA 2I4GA 2HXPA 2J17A 4ZI4A 4J51A 3V0GA 1L8GA 4OHHA 2FJMA 2NTAA 3F9AA 2BGEA 3RO1A 1G4US 5KABA 2I1YA 2I6MA 4IKCA 3QKQA 1PTYA 3NMEA 3ZM1A 1GWZA 2HNQA 4AZ1A 5I6VA 1NNYA 3F81A 4GE2A 5EHPA 4ZN5A 2I5XA 2I6OA 2FH7A 2F6ZA 1YWFA 3OLRA 4RI4A 2F46A 2H4KA 3V0EA 4RDDA 2PSZA 1PYNA 5HDEA 3RZ2A 4NX8A 2I4EA 1U25A 2I3UA 3AWGA 1C87A 2B4OA 1LARA 3QKPA 1RXDA 3ZMQA 1C88A 1OEUA 3A5JA 2J16B 3A5KA 2P4DA 1NL9A 3EZZA 2QCTA 4NWFA 4RH9A 2GP0A 3O5XA 1ZZWA 1YTNA 1PTVA 1XXPA 1ZCLA 2NZ6A 1C86A 1P15A 4GRZA 1PTUA 2PBNA 2I42A 2CNGA 5BUGA 5KA9A 3O4SA 4D3PA 5IBMA 3F9BA 1KAVA 2VEYA 2B4SA 3V0DA 3BM8A 1BZJA 1OEVA 2CM2A 3ZM3A 2QDMA 3PS5A 3LJ8A 2M3VA 1D5RA 2BGDA 3D1QA 2HNPA 4Y2EA 1Q6MA 3S3FA 2HY3A 3ZV2A 2C46A 2QDCA 1ONYA 1YGRA 1X24A 3CM3A 4I8NA 4HJPA 2BV5A 4QAPA 1RPMA 3GXHA 3QCGA 4R0SA 3GXGA 2FJNA 1XXVA 3V0HA 3QCHA 2C7SA 3ZM2A 4DGPA 4YAAA 2VEWA 2PI7A 2F6YA 1YN9A 5KA1A 4Z6BA 2HC2A 2BZLA 1EENA 1Q1MA 1QXKA 1OHCA 5KA3A 4WU2A 3M4UA 3SMEA 2P6XA 4GFVA 1G7GA 4H34A 4GWFA 1YZ4A 3SR9A 1ONZA 5EHRA 2OC3A 5K22A 3CWEA 2F6FA 2Y96A 2VEUA 3BRHA 2DXPA 1PXHA 1G4WR 1YPTA 3QCFA 5K25A 1C85A 2GWOA 4Y14A 2BIJA 4HRFA 5K23A 3D42A 2OOQA 4GE5A 2CMBA 2MBCA 2H4GA 1SUGA 2G6ZA 3AWFA 4QUNA 3QCIA 3QCEA 4NNDA 3V0JA 3S3KA 5M43A 5KA7A 4NWGA 4PVGA 2PQ5A 3RGQA 4JMJA 5KAAA 1C83A 1T48A 2CMCA 5GTJA 2ZMMA 4R0TA 2CNHA 3EAXA 3QCDA 5K9VA 1YTSA 2E0TA 2CMAA 2I4HA 2QBQA 4WTYA 1YGUA 2QEPA 2F6TA 1OHEA 2B49A 3V0IA 3QCKA 3EB1A 4TVVA 2I6IA 3QCNA 1G1GA 1G1HA 1G1FA 3B7OA 1M3GA 1NWEA 5KA2A 4QAHA 2CM3A 1U26A 3O3LA 3QCJA 3I80A 4KYQA 1XM2A 1AAXA 2J16A 3MMJA 1PA1A 2Q05A 2I75A 3MOWA 1PTTA 5KADA 3I36A 4JBCA 2CM8A 4GE6A 4KI9A 5AWXA 2I3RA 2CNFA 4HJQA 2I6JA 2HCMA 2ESBA 3V0FA 2H4VA 4DGXA 2Y2FA 3OMHA 1PH0A 2F70A 2NT7A 3QCBA 1Q6PA 1LQFA 1FPRA 3D1OA 2NT2A 2VEXA 4RI5A 2H04A 1MKPA 2QBRA 3D1HA 1LYVA 3ZM0A 3S4EA 2RF6A 3I7ZA 4OHEA 1GFYA 4ZRTA 3AWEA 3BLUA 1FQ1A 2CFVA 1NZ7A 2WGPA 4D3QA 5IBSA 4NYHA 2B4PA 4R30A 2I6PA 1U24A 3O4TA 1G7FA 4GFUA 3ZMPA 1QZ0A 5J8RA 1T4JA 4H1OA 1WCHA 5KA0A 2HC1A 2OUDA 3QCMA 1ZCKA 1L8KA 2B4UA 3S3HA 4JMKA 5KACA 2F6WA 1WRMA 2CJZA 2NV5A 2H02A 1BZHA 2B07A 5K9WA 1ZC0A 3F41A 1ECVA 1R6HA 2SHPA 4MBBA 4QBEA 1WAXA 1Q6JA 1FPZA 2PA5A 2HB1A 4D3RA 2A8BA 4RH5A 4PYHA 2JJDA 4WU3A 3S3EA 1A5YA 5K24A 1T49A 1EEOA 4KYRA 2GJTA 1VHRA 1Q6TA 5KA4A 2F6VA 3EU0A 3D44A 5BX1A 5LXQB 1JF7A 3N0AA 1YTWA 3D9CA 3U96A 2PT0A 1YFOA 1J4XA 5MMZB 2A3KA 4BPCA 1I57A 4GS0A 1XRIA 2AZRA 1C84A 3F99A 2F71A 3BLTA 4ICZA 2QBSA 2HVLA 1OETA 4GRYA 4QBWA 4RHGA 1KAKA 3H2XA 5BZZA 1V3AA 4B04A 4BJOA 1JLNA 2CNEA 4S0GA 1Q6NA 2CM7A 1I9SA 1OHDA 2OZ5A 2R0BA 4QUMA 4OHDA 2CNIA 4OHIA 2NLKA 4ERCA 4RKKA 1OESA 1XBOA 2QDPA 3EMUA 2YDUA 4OHLA 1NWLA 3MOZA 1NO6A 3QCCA 2H03A 5BZXA 2Q47A 3S4OA 1OEOX 5KA8A 3QCLA 2IMGA 2QBPA 2QCJA 2VEVA 4JNBA 2ZN7A 2B3OA 1Q6SA 2G59A 4YR8B 1PA9A 1BZCA 1I9TA 3O4UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RGO A;  1OEM X;  2AHS A;  4WOH A;  2I4G A;  2HXP A;  2J17 A;  4ZI4 A;  4J51 A;  3V0G A;  1L8G A;  4OHH A;  2FJM A;  2NTA A;  3F9A A;  2BGE A;  3RO1 A;  1G4U S;  5KAB A;  2I1Y A;  2I6M A;  4IKC A;  3QKQ A;  1PTY A;  3NME A;  3ZM1 A;  1GWZ A;  2HNQ A;  4AZ1 A;  5I6V A;  1NNY A;  3F81 A;  4GE2 A;  5EHP A;  4ZN5 A;  2I5X A;  2I6O A;  2FH7 A;  2F6Z A;  1YWF A;  3OLR A;  4RI4 A;  2F46 A;  2H4K A;  3V0E A;  4RDD A;  2PSZ A;  1PYN A;  5HDE A;  3RZ2 A;  4NX8 A;  2I4E A;  1U25 A;  2I3U A;  3AWG A;  1C87 A;  2B4O A;  1LAR A;  3QKP A;  1RXD A;  3ZMQ A;  1C88 A;  1OEU A;  3A5J A;  2J16 B;  3A5K A;  2P4D A;  1NL9 A;  3EZZ A;  2QCT A;  4NWF A;  4RH9 A;  2GP0 A;  3O5X A;  1ZZW A;  1YTN A;  1PTV A;  1XXP A;  1ZCL A;  2NZ6 A;  1C86 A;  1P15 A;  4GRZ A;  1PTU A;  2PBN A;  2I42 A;  2CNG A;  5BUG A;  5KA9 A;  3O4S A;  4D3P A;  5IBM A;  3F9B A;  1KAV A;  2VEY A;  2B4S A;  3V0D A;  3BM8 A;  1BZJ A;  1OEV A;  2CM2 A;  3ZM3 A;  2QDM A;  3PS5 A;  3LJ8 A;  2M3V A;  1D5R A;  2BGD A;  3D1Q A;  2HNP A;  4Y2E A;  1Q6M A;  3S3F A;  2HY3 A;  3ZV2 A;  2C46 A;  2QDC A;  1ONY A;  1YGR A;  1X24 A;  3CM3 A;  4I8N A;  4HJP A;  2BV5 A;  4QAP A;  1RPM A;  3GXH A;  3QCG A;  4R0S A;  3GXG A;  2FJN A;  1XXV A;  3V0H A;  3QCH A;  2C7S A;  3ZM2 A;  4DGP A;  4YAA A;  2VEW A;  2PI7 A;  2F6Y A;  1YN9 A;  5KA1 A;  4Z6B A;  2HC2 A;  2BZL A;  1EEN A;  1Q1M A;  1QXK A;  1OHC A;  5KA3 A;  4WU2 A;  3M4U A;  3SME A;  2P6X A;  4GFV A;  1G7G A;  4H34 A;  4GWF A;  1YZ4 A;  3SR9 A;  1ONZ A;  5EHR A;  2OC3 A;  5K22 A;  3CWE A;  2F6F A;  2Y96 A;  2VEU A;  3BRH A;  2DXP A;  1PXH A;  1G4W R;  1YPT A;  3QCF A;  5K25 A;  1C85 A;  2GWO A;  4Y14 A;  2BIJ A;  4HRF A;  5K23 A;  3D42 A;  2OOQ A;  4GE5 A;  2CMB A;  2MBC A;  2H4G A;  1SUG A;  2G6Z A;  3AWF A;  4QUN A;  3QCI A;  3QCE A;  4NND A;  3V0J A;  3S3K A;  5M43 A;  5KA7 A;  4NWG A;  4PVG A;  2PQ5 A;  3RGQ A;  4JMJ A;  5KAA A;  1C83 A;  1T48 A;  2CMC A;  5GTJ A;  2ZMM A;  4R0T A;  2CNH A;  3EAX A;  3QCD A;  5K9V A;  1YTS A;  2E0T A;  2CMA A;  2I4H A;  2QBQ A;  4WTY A;  1YGU A;  2QEP A;  2F6T A;  1OHE A;  2B49 A;  3V0I A;  3QCK A;  3EB1 A;  4TVV A;  2I6I A;  3QCN A;  1G1G A;  1G1H A;  1G1F A;  3B7O A;  1M3G A;  1NWE A;  5KA2 A;  4QAH A;  2CM3 A;  1U26 A;  3O3L A;  3QCJ A;  3I80 A;  4KYQ A;  1XM2 A;  1AAX A;  2J16 A;  3MMJ A;  1PA1 A;  2Q05 A;  2I75 A;  3MOW A;  1PTT A;  5KAD A;  3I36 A;  4JBC A;  2CM8 A;  4GE6 A;  4KI9 A;  5AWX A;  2I3R A;  2CNF A;  4HJQ A;  2I6J A;  2HCM A;  2ESB A;  3V0F A;  2H4V A;  4DGX A;  2Y2F A;  3OMH A;  1PH0 A;  2F70 A;  2NT7 A;  3QCB A;  1Q6P A;  1LQF A;  1FPR A;  3D1O A;  2NT2 A;  2VEX A;  4RI5 A;  2H04 A;  1MKP A;  2QBR A;  3D1H A;  1LYV A;  3ZM0 A;  3S4E A;  2RF6 A;  3I7Z A;  4OHE A;  1GFY A;  4ZRT A;  3AWE A;  3BLU A;  1FQ1 A;  2CFV A;  1NZ7 A;  2WGP A;  4D3Q A;  5IBS A;  4NYH A;  2B4P A;  4R30 A;  2I6P A;  1U24 A;  3O4T A;  1G7F A;  4GFU A;  3ZMP A;  1QZ0 A;  5J8R A;  1T4J A;  4H1O A;  1WCH A;  5KA0 A;  2HC1 A;  2OUD A;  3QCM A;  1ZCK A;  1L8K A;  2B4U A;  3S3H A;  4JMK A;  5KAC A;  2F6W A;  1WRM A;  2CJZ A;  2NV5 A;  2H02 A;  1BZH A;  2B07 A;  5K9W A;  1ZC0 A;  3F41 A;  1ECV A;  1R6H A;  2SHP A;  4MBB A;  4QBE A;  1WAX A;  1Q6J A;  1FPZ A;  2PA5 A;  2HB1 A;  4D3R A;  2A8B A;  4RH5 A;  4PYH A;  2JJD A;  4WU3 A;  3S3E A;  1A5Y A;  5K24 A;  1T49 A;  1EEO A;  4KYR A;  2GJT A;  1VHR A;  1Q6T A;  5KA4 A;  2F6V A;  3EU0 A;  3D44 A;  5BX1 A;  5LXQ B;  1JF7 A;  3N0A A;  1YTW A;  3D9C A;  3U96 A;  2PT0 A;  1YFO A;  1J4X A;  5MMZ B;  2A3K A;  4BPC A;  1I57 A;  4GS0 A;  1XRI A;  2AZR A;  1C84 A;  3F99 A;  2F71 A;  3BLT A;  4ICZ A;  2QBS A;  2HVL A;  1OET A;  4GRY A;  4QBW A;  4RHG A;  1KAK A;  3H2X A;  5BZZ A;  1V3A A;  4B04 A;  4BJO A;  1JLN A;  2CNE A;  4S0G A;  1Q6N A;  2CM7 A;  1I9S A;  1OHD A;  2OZ5 A;  2R0B A;  4QUM A;  4OHD A;  2CNI A;  4OHI A;  2NLK A;  4ERC A;  4RKK A;  1OES A;  1XBO A;  2QDP A;  3EMU A;  2YDU A;  4OHL A;  1NWL A;  3MOZ A;  1NO6 A;  3QCC A;  2H03 A;  5BZX A;  2Q47 A;  3S4O A;  1OEO X;  5KA8 A;  3QCL A;  2IMG A;  2QBP A;  2QCJ A;  2VEV A;  4JNB A;  2ZN7 A;  2B3O A;  1Q6S A;  2G59 A;  4YR8 B;  1PA9 A;  1BZC A;  1I9T A;  3O4U A; 
#chains in the Genus database with same CATH topology
 3RGO A;  1GQY A;  1OEM X;  3LK7 A;  2AHS A;  4WOH A;  2I4G A;  1JBW A;  2HXP A;  2J17 A;  4ZI4 A;  4J51 A;  3V0G A;  1L8G A;  4OHH A;  2FJM A;  1FGS A;  2NTA A;  3F9A A;  2BGE A;  3HN7 A;  3RO1 A;  1G4U S;  5KAB A;  2I1Y A;  2I6M A;  4IKC A;  3QKQ A;  1PTY A;  3NME A;  3ZM1 A;  1GWZ A;  2HNQ A;  4AZ1 A;  5I6V A;  1NNY A;  3F81 A;  4GE2 A;  5EHP A;  4ZN5 A;  2I5X A;  2I6O A;  2AM1 A;  2FH7 A;  2WTZ A;  3ZM5 A;  2F6Z A;  1YWF A;  3OLR A;  4RI4 A;  1W7K A;  2F46 A;  2H4K A;  3V0E A;  4RDD A;  2PSZ A;  1PYN A;  5HDE A;  3RZ2 A;  4NX8 A;  2I4E A;  1U25 A;  2I3U A;  3N2A A;  3AWG A;  1EEH A;  1W78 A;  1C87 A;  2XJA A;  2B4O A;  1LAR A;  3QKP A;  1RXD A;  3ZMQ A;  1C88 A;  1OEU A;  3A5J A;  4BUC A;  2VOS A;  2J16 B;  3A5K A;  2P4D A;  1O5Z A;  1NL9 A;  3EZZ A;  2QCT A;  4NWF A;  4RH9 A;  3UAG A;  2GP0 A;  4HV4 A;  2UAG A;  3O5X A;  1ZZW A;  2WJP A;  1YTN A;  4QF5 A;  1PTV A;  1XXP A;  1ZCL A;  2NZ6 A;  1C86 A;  2Y67 A;  1P15 A;  4GRZ A;  1PTU A;  2PBN A;  2I42 A;  2CNG A;  5BUG A;  5KA9 A;  3O4S A;  4D3P A;  5IBM A;  3F9B A;  1KAV A;  2VEY A;  2B4S A;  3V0D A;  3BM8 A;  4ZIY A;  1BZJ A;  1OEV A;  2CM2 A;  3ZM3 A;  2QDM A;  3PS5 A;  3LJ8 A;  2M3V A;  4CVM A;  1D5R A;  2BGD A;  3D1Q A;  2HNP A;  4Y2E A;  1Q6M A;  2VOR A;  3S3F A;  2HY3 A;  3ZV2 A;  2C46 A;  2QDC A;  1ONY A;  1YGR A;  2Y66 A;  1X24 A;  2UUP A;  3CM3 A;  4I8N A;  4HJP A;  2BV5 A;  4QAP A;  1RPM A;  3GXH A;  3QCG A;  4R0S A;  2AM2 A;  3GXG A;  2FJN A;  1XXV A;  3V0H A;  3QCH A;  2C7S A;  3ZM2 A;  4DGP A;  4YAA A;  2VEW A;  2PI7 A;  2F6Y A;  1YN9 A;  1J6U A;  5KA1 A;  4Z6B A;  2HC2 A;  2BZL A;  1EEN A;  5A5F A;  1Q1M A;  1QXK A;  1OHC A;  5KA3 A;  4WU2 A;  3M4U A;  3SME A;  2JFG A;  2P6X A;  2UUO A;  1G7G A;  4GFV A;  4H34 A;  4GWF A;  1YZ4 A;  3SR9 A;  4CVK A;  1ONZ A;  5EHR A;  4C13 A;  2F00 A;  2OC3 A;  5K22 A;  3CWE A;  2F6F A;  2Y96 A;  2VEU A;  1P3D A;  3BRH A;  2DXP A;  1PXH A;  1G4W R;  1YPT A;  3QCF A;  5K25 A;  1C85 A;  2GWO A;  4Y14 A;  2BIJ A;  4HRF A;  1GQQ A;  3D42 A;  5K23 A;  2OOQ A;  4GE5 A;  2CMB A;  2MBC A;  2H4G A;  1SUG A;  2G6Z A;  3AWF A;  4QUN A;  3QCI A;  3QCE A;  4NND A;  3V0J A;  3S3K A;  5M43 A;  5KA7 A;  4NWG A;  4PVG A;  2PQ5 A;  3RGQ A;  4JMJ A;  5KAA A;  1C83 A;  1T48 A;  2CMC A;  5GTJ A;  2JFF A;  2ZMM A;  2CNH A;  3EAX A;  4R0T A;  3QCD A;  5A5E A;  5K9V A;  2Y1O A;  1YTS A;  2E0T A;  2CMA A;  2I4H A;  2QBQ A;  4WTY A;  1YGU A;  2QEP A;  3ZM6 A;  2F6T A;  1OHE A;  2B49 A;  3V0I A;  3QCK A;  3EB1 A;  4TVV A;  2I6I A;  3ZL8 A;  3QCN A;  1G1G A;  1G1H A;  1G1F A;  3B7O A;  1M3G A;  1NWE A;  5KA2 A;  4QAH A;  2CM3 A;  1U26 A;  3O3L A;  3QCJ A;  3I80 A;  4KYQ A;  1XM2 A;  1AAX A;  2J16 A;  3MMJ A;  1PA1 A;  2VTD A;  2Q05 A;  2I75 A;  2XPC A;  3MOW A;  1PTT A;  2GCA A;  5KAD A;  3I36 A;  4JBC A;  2CM8 A;  4GE6 A;  4KI9 A;  5AWX A;  2I3R A;  2CNF A;  4HJQ A;  2I6J A;  1UAG A;  2HCM A;  2ESB A;  3V0F A;  2H4V A;  4DGX A;  2JFH A;  4UAG A;  2Y2F A;  3OMH A;  1PH0 A;  2F70 A;  2NT7 A;  3QCB A;  1LQF A;  1FPR A;  1Q6P A;  3D1O A;  3MVN A;  2NT2 A;  2VEX A;  4RI5 A;  3QCZ A;  2GC6 A;  2H04 A;  1E8C A;  1MKP A;  2QBR A;  3D1H A;  1LYV A;  3ZM0 A;  3S4E A;  2RF6 A;  3I7Z A;  2GCB A;  4QDI A;  4OHE A;  1GFY A;  4ZRT A;  3AWE A;  4C12 A;  3BLU A;  1FQ1 A;  2CFV A;  1NZ7 A;  2WGP A;  4D3Q A;  5IBS A;  4NYH A;  2B4P A;  4R30 A;  2I6P A;  1U24 A;  3O4T A;  4CVL A;  1G7F A;  4GFU A;  3ZMP A;  1QZ0 A;  5J8R A;  1T4J A;  1JBV A;  4H1O A;  1WCH A;  5KA0 A;  2HC1 A;  2OUD A;  3QCM A;  1ZCK A;  3NRS A;  1L8K A;  2B4U A;  3S3H A;  4JMK A;  5KAC A;  2F6W A;  1WRM A;  2VTE A;  2CJZ A;  2NV5 A;  2H02 A;  1BZH A;  2B07 A;  5K9W A;  1ZC0 A;  3F41 A;  1ECV A;  1R6H A;  2SHP A;  4MBB A;  4QBE A;  1WAX A;  1Q6J A;  1FPZ A;  2PA5 A;  2HB1 A;  4D3R A;  2A8B A;  4RH5 A;  4PYH A;  2JJD A;  4WU3 A;  3S3E A;  1A5Y A;  5K24 A;  1T49 A;  1EEO A;  4KYR A;  2GJT A;  1VHR A;  1Q6T A;  5KA4 A;  2X5O A;  2F6V A;  3EU0 A;  3D44 A;  5BX1 A;  5LXQ B;  2GC5 A;  1JF7 A;  3N0A A;  1YTW A;  3D9C A;  1P31 A;  2PT0 A;  3U96 A;  1YFO A;  1J4X A;  5MMZ B;  2A3K A;  4BPC A;  1I57 A;  4GS0 A;  2Y68 A;  3PYZ A;  1XRI A;  2AZR A;  1C84 A;  3F99 A;  2F71 A;  3BLT A;  4ICZ A;  2QBS A;  2HVL A;  1OET A;  4GRY A;  4QBW A;  4RHG A;  1KAK A;  3H2X A;  5BZZ A;  1V3A A;  4B04 A;  4BJO A;  1JLN A;  2CNE A;  4S0G A;  1Q6N A;  1GG4 A;  2CM7 A;  1I9S A;  1OHD A;  2OZ5 A;  2R0B A;  4QUM A;  4OHD A;  2CNI A;  4OHI A;  2NLK A;  4ERC A;  4RKK A;  1OES A;  1XBO A;  2QDP A;  3EMU A;  2YDU A;  4OHL A;  1NWL A;  3MOZ A;  1NO6 A;  3QCC A;  2H03 A;  5BZX A;  2Q47 A;  3S4O A;  1OEO X;  5KA8 A;  3QCL A;  2IMG A;  2QBP A;  2QCJ A;  2VEV A;  4JNB A;  4BUB A;  2ZN7 A;  2B3O A;  1Q6S A;  2G59 A;  4YR8 B;  1PA9 A;  1E0D A;  1BZC A;  1I9T A;  3O4U A; 
#chains in the Genus database with same CATH homology
 3RGO A;  1OEM X;  2AHS A;  4WOH A;  2I4G A;  2HXP A;  2J17 A;  4ZI4 A;  4J51 A;  3V0G A;  1L8G A;  4OHH A;  2FJM A;  2NTA A;  3F9A A;  2BGE A;  3RO1 A;  1G4U S;  5KAB A;  2I1Y A;  2I6M A;  4IKC A;  3QKQ A;  1PTY A;  3NME A;  3ZM1 A;  1GWZ A;  2HNQ A;  4AZ1 A;  5I6V A;  1NNY A;  3F81 A;  4GE2 A;  5EHP A;  4ZN5 A;  2I5X A;  2I6O A;  2FH7 A;  2F6Z A;  1YWF A;  3OLR A;  4RI4 A;  2F46 A;  2H4K A;  3V0E A;  4RDD A;  2PSZ A;  1PYN A;  5HDE A;  3RZ2 A;  4NX8 A;  2I4E A;  1U25 A;  2I3U A;  3AWG A;  1C87 A;  2B4O A;  1LAR A;  3QKP A;  1RXD A;  3ZMQ A;  1C88 A;  1OEU A;  3A5J A;  2J16 B;  3A5K A;  2P4D A;  1NL9 A;  3EZZ A;  2QCT A;  4NWF A;  4RH9 A;  2GP0 A;  3O5X A;  1ZZW A;  1YTN A;  1PTV A;  1XXP A;  1ZCL A;  2NZ6 A;  1C86 A;  1P15 A;  4GRZ A;  1PTU A;  2PBN A;  2I42 A;  2CNG A;  5BUG A;  5KA9 A;  3O4S A;  4D3P A;  5IBM A;  3F9B A;  1KAV A;  2VEY A;  2B4S A;  3V0D A;  3BM8 A;  1BZJ A;  1OEV A;  2CM2 A;  3ZM3 A;  2QDM A;  3PS5 A;  3LJ8 A;  2M3V A;  1D5R A;  2BGD A;  3D1Q A;  2HNP A;  4Y2E A;  1Q6M A;  3S3F A;  2HY3 A;  3ZV2 A;  2C46 A;  2QDC A;  1ONY A;  1YGR A;  1X24 A;  3CM3 A;  4I8N A;  4HJP A;  2BV5 A;  4QAP A;  1RPM A;  3GXH A;  3QCG A;  4R0S A;  3GXG A;  2FJN A;  1XXV A;  3V0H A;  3QCH A;  2C7S A;  3ZM2 A;  4DGP A;  4YAA A;  2VEW A;  2PI7 A;  2F6Y A;  1YN9 A;  5KA1 A;  4Z6B A;  2HC2 A;  2BZL A;  1EEN A;  1Q1M A;  1QXK A;  1OHC A;  5KA3 A;  4WU2 A;  3M4U A;  3SME A;  2P6X A;  4GFV A;  1G7G A;  4H34 A;  4GWF A;  1YZ4 A;  3SR9 A;  1ONZ A;  5EHR A;  2OC3 A;  5K22 A;  3CWE A;  2F6F A;  2Y96 A;  2VEU A;  3BRH A;  2DXP A;  1PXH A;  1G4W R;  1YPT A;  3QCF A;  5K25 A;  1C85 A;  2GWO A;  4Y14 A;  2BIJ A;  4HRF A;  5K23 A;  3D42 A;  2OOQ A;  4GE5 A;  2CMB A;  2MBC A;  2H4G A;  1SUG A;  2G6Z A;  3AWF A;  4QUN A;  3QCI A;  3QCE A;  4NND A;  3V0J A;  3S3K A;  5M43 A;  5KA7 A;  4NWG A;  4PVG A;  2PQ5 A;  3RGQ A;  4JMJ A;  5KAA A;  1C83 A;  1T48 A;  2CMC A;  5GTJ A;  2ZMM A;  4R0T A;  2CNH A;  3EAX A;  3QCD A;  5K9V A;  1YTS A;  2E0T A;  2CMA A;  2I4H A;  2QBQ A;  4WTY A;  1YGU A;  2QEP A;  2F6T A;  1OHE A;  2B49 A;  3V0I A;  3QCK A;  3EB1 A;  4TVV A;  2I6I A;  3QCN A;  1G1G A;  1G1H A;  1G1F A;  3B7O A;  1M3G A;  1NWE A;  5KA2 A;  4QAH A;  2CM3 A;  1U26 A;  3O3L A;  3QCJ A;  3I80 A;  4KYQ A;  1XM2 A;  1AAX A;  2J16 A;  3MMJ A;  1PA1 A;  2Q05 A;  2I75 A;  3MOW A;  1PTT A;  5KAD A;  3I36 A;  4JBC A;  2CM8 A;  4GE6 A;  4KI9 A;  5AWX A;  2I3R A;  2CNF A;  4HJQ A;  2I6J A;  2HCM A;  2ESB A;  3V0F A;  2H4V A;  4DGX A;  2Y2F A;  3OMH A;  1PH0 A;  2F70 A;  2NT7 A;  3QCB A;  1Q6P A;  1LQF A;  1FPR A;  3D1O A;  2NT2 A;  2VEX A;  4RI5 A;  2H04 A;  1MKP A;  2QBR A;  3D1H A;  1LYV A;  3ZM0 A;  3S4E A;  2RF6 A;  3I7Z A;  4OHE A;  1GFY A;  4ZRT A;  3AWE A;  3BLU A;  1FQ1 A;  2CFV A;  1NZ7 A;  2WGP A;  4D3Q A;  5IBS A;  4NYH A;  2B4P A;  4R30 A;  2I6P A;  1U24 A;  3O4T A;  1G7F A;  4GFU A;  3ZMP A;  1QZ0 A;  5J8R A;  1T4J A;  4H1O A;  1WCH A;  5KA0 A;  2HC1 A;  2OUD A;  3QCM A;  1ZCK A;  1L8K A;  2B4U A;  3S3H A;  4JMK A;  5KAC A;  2F6W A;  1WRM A;  2CJZ A;  2NV5 A;  2H02 A;  1BZH A;  2B07 A;  5K9W A;  1ZC0 A;  3F41 A;  1ECV A;  1R6H A;  2SHP A;  4MBB A;  4QBE A;  1WAX A;  1Q6J A;  1FPZ A;  2PA5 A;  2HB1 A;  4D3R A;  2A8B A;  4RH5 A;  4PYH A;  2JJD A;  4WU3 A;  3S3E A;  1A5Y A;  5K24 A;  1T49 A;  1EEO A;  4KYR A;  2GJT A;  1VHR A;  1Q6T A;  5KA4 A;  2F6V A;  3EU0 A;  3D44 A;  5BX1 A;  5LXQ B;  1JF7 A;  3N0A A;  1YTW A;  3D9C A;  3U96 A;  2PT0 A;  1YFO A;  1J4X A;  5MMZ B;  2A3K A;  4BPC A;  1I57 A;  4GS0 A;  1XRI A;  2AZR A;  1C84 A;  3F99 A;  2F71 A;  3BLT A;  4ICZ A;  2QBS A;  2HVL A;  1OET A;  4GRY A;  4QBW A;  4RHG A;  1KAK A;  3H2X A;  5BZZ A;  1V3A A;  4B04 A;  4BJO A;  1JLN A;  2CNE A;  4S0G A;  1Q6N A;  2CM7 A;  1I9S A;  1OHD A;  2OZ5 A;  2R0B A;  4QUM A;  4OHD A;  2CNI A;  4OHI A;  2NLK A;  4ERC A;  4RKK A;  1OES A;  1XBO A;  2QDP A;  3EMU A;  2YDU A;  4OHL A;  1NWL A;  3MOZ A;  1NO6 A;  3QCC A;  2H03 A;  5BZX A;  2Q47 A;  3S4O A;  1OEO X;  5KA8 A;  3QCL A;  2IMG A;  2QBP A;  2QCJ A;  2VEV A;  4JNB A;  2ZN7 A;  2B3O A;  1Q6S A;  2G59 A;  4YR8 B;  1PA9 A;  1BZC A;  1I9T A;  3O4U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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