2H03A

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
288
structure length
288
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSGGSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein tyrosine phosphatase, receptor type, B,
total genus 101
structure length 288
sequence length 288
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2h03A00
3QKQA 5BZXA 1T49A 3D1QA 2I42A 2C46A 1PTVA 2CM8A 2CMAA 2MBCA 4ZI4A 1Q6MA 2J16A 1YN9A 5AWXA 3I36A 2G59A 3RGQA 1NWLA 3ZMQA 2Q05A 2HVLA 1FQ1A 4KYRA 1PA1A 3EZZA 2PQ5A 4GRYA 2R0BA 3BLTA 2I3UA 1D5RA 3PS5A 2OZ5A 1ONZA 3U96A 4H34A 4OHIA 4GFVA 1Q6SA 2BGDA 4MBBA 1C87A 2BGEA 4DGPA 1JLNA 3N0AA 3LJ8A 3S3HA 4JBCA 2Y96A 4GFUA 5KA2A 2FJMA 4BJOA 1I57A 3D1OA 2HNPA 2CM3A 2F46A 2FJNA 2A3KA 4QAHA 1OEMX 3D44A 2NTAA 3F81A 4GE5A 3F99A 3H2XA 1SUGA 1JF7A 2QBRA 2CMCA 1ONYA 1BZJA 2F70A 2OUDA 4OHHA 3ZM3A 2B49A 1YWFA 3O4TA 4B04A 2F6VA 2ZMMA 1NL9A 4D3PA 4HJQA 2CNFA 3BRHA 3EU0A 3QCCA 1KAVA 1Q6TA 1L8KA 2QCTA 4RDDA 2SHPA 5KA8A 3QCBA 1OHDA 1FPZA 3QCIA 5KA1A 2PA5A 1Q6JA 3B7OA 3OLRA 5KA0A 3QCDA 3EMUA 1YTSA 1YZ4A 2P6XA 1QZ0A 1YPTA 1U25A 3GXHA 1QXKA 1PH0A 2H04A 5BUGA 2AZRA 5BX1A 2VEYA 2FH7A 1V3AA 3V0IA 1WCHA 1OEUA 3QCJA 4JMJA 4Y14A 4WU3A 2GWOA 1OEVA 2CNIA 2I6PA 3D42A 2I4EA 4WOHA 1PXHA 1T48A 2I4GA 2NZ6A 4JMKA 4ICZA 3V0FA 1ZCKA 3I80A 1YGRA 1PTUA 2HC2A 1C83A 5KA9A 1A5YA 2DXPA 2I6OA 3V0DA 1XBOA 3F41A 2I5XA 2CJZA 1PTYA 2QDPA 4OHDA 5EHPA 5KADA 2BIJA 4WU2A 4JNBA 4NWGA 3MOZA 2JJDA 1NWEA 2B3OA 1OESA 1T4JA 2CNHA 5K24A 2CNGA 5KAAA 2I1YA 4RH9A 3MOWA 2QBSA 4QAPA 4NNDA 4J51A 4R0SA 2BV5A 3F9BA 5K25A 4ZN5A 2HCMA 1G1FA 1L8GA 2PBNA 1YGUA 1PA9A 1LQFA 1GFYA 4QUMA 1RXDA 2F6WA 1C85A 2IMGA 2J16B 1OEOX 5KACA 2VEUA 1Q6PA 4AZ1A 2H03A 1I9TA 2VEVA 3I7ZA 3V0JA 1R6HA 2WGPA 2VEWA 1X24A 5I6VA 4OHLA 5K9VA 4WTYA 4Y2EA 1G1HA 4PYHA 1BZHA 5HDEA 3MMJA 1I9SA 3V0HA 3QKPA 5LXQB 1VHRA 1XM2A 1MKPA 4GE6A 4ERCA 3QCHA 3O5XA 3F9AA 2QDCA 2OOQA 2I4HA 1J4XA 3O4SA 1WAXA 1Q1MA 2B4UA 2QDMA 4GS0A 3QCKA 1AAXA 4YR8B 2NV5A 3ZM2A 2I75A 1OETA 4ZRTA 3V0EA 1G1GA 4QUNA 3QCFA 3A5KA 1YTNA 1OHEA 2QCJA 3BLUA 1GWZA 1U26A 1ZZWA 2HXPA 1ZCLA 3AWFA 1ZC0A 3S3FA 1P15A 1RPMA 2CNEA 3CM3A 2F6TA 2PSZA 2F6YA 4TVVA 4IKCA 3AWGA 4H1OA 2VEXA 2I3RA 2F6FA 2B4SA 3D9CA 4QBWA 2F6ZA 3EAXA 2HY3A 5IBMA 4RH5A 1EEOA 2AHSA 2GP0A 1NNYA 4RI4A 1XRIA 5IBSA 2M3VA 1PTTA 2H4GA 3RO1A 3BM8A 4GRZA 2ESBA 4RHGA 3SR9A 5EHRA 5KABA 2P4DA 5KA4A 1BZCA 2OC3A 3QCNA 2C7SA 1YFOA 2I6MA 3QCGA 3EB1A 2PI7A 2NLKA 2J17A 5M43A 3O3LA 4DGXA 5GTJA 2G6ZA 1G4US 3V0GA 4D3RA 1G7FA 3M4UA 3S4EA 2CM2A 4OHEA 4D3QA 5MMZB 1WRMA 2CFVA 3RGOA 3RZ2A 4GWFA 4YAAA 2ZN7A 4QBEA 3ZM1A 1PYNA 2HNQA 2CM7A 4RKKA 1U24A 2F71A 3QCLA 3AWEA 1C86A 5KA3A 4R0TA 1ECVA 2A8BA 2HB1A 2NT7A 4NX8A 4NWFA 4BPCA 3S3KA 2PT0A 4R30A 2Y2FA 3QCEA 1YTWA 4S0GA 5BZZA 4KYQA 2RF6A 5KA7A 4HRFA 1XXPA 2I6IA 2NT2A 2Q47A 1NZ7A 3ZM0A 4GE2A 2H02A 3CWEA 2H4KA 1OHCA 2CMBA 4NYHA 2YDUA 4Z6BA 3S3EA 3QCMA 3NMEA 2QBPA 3ZV2A 1M3GA 3GXGA 1C84A 2B07A 1EENA 4I8NA 1LARA 1LYVA 2BZLA 2B4PA 2HC1A 2B4OA 5J8RA 1C88A 3OMHA 5K9WA 1G4WR 1G7GA 2E0TA 4RI5A 3O4UA 1Q6NA 2H4VA 2QBQA 3D1HA 2GJTA 2QEPA 3A5JA 4HJPA 2I6JA 4KI9A 3ZMPA 5K22A 1FPRA 1XXVA 3SMEA 5K23A 1NO6A 1KAKA 4PVGA 3S4OA
chains in the Genus database with same CATH superfamily
2GC5A 3QKQA 5BZXA 1T49A 3D1QA 2I42A 2C46A 1PTVA 2CM8A 2JFFA 4CVKA 2F00A 2CMAA 2MBCA 4ZI4A 1Q6MA 2J16A 1YN9A 5AWXA 3I36A 2G59A 3RGQA 1NWLA 3ZMQA 1O5ZA 2HVLA 2Q05A 1FQ1A 4KYRA 1PA1A 3EZZA 2PQ5A 4GRYA 2R0BA 3BLTA 2I3UA 1D5RA 3PS5A 2OZ5A 1ONZA 2X5OA 3U96A 1P31A 4H34A 4OHIA 4GFVA 3LK7A 1Q6SA 2BGDA 2AM2A 4MBBA 1C87A 2BGEA 4DGPA 1JLNA 3ZM6A 3N0AA 3LJ8A 3S3HA 4JBCA 2Y96A 4C12A 4GFUA 5KA2A 2FJMA 4BJOA 1I57A 3D1OA 2HNPA 2CM3A 2F46A 2FJNA 2A3KA 4QAHA 1OEMX 3D44A 2NTAA 3F81A 4GE5A 3F99A 1UAGA 3H2XA 1SUGA 1JF7A 2QBRA 2CMCA 1ONYA 1BZJA 2F70A 2OUDA 4OHHA 3ZM3A 2B49A 1YWFA 3O4TA 4B04A 2F6VA 2ZMMA 1NL9A 4D3PA 4HJQA 2CNFA 3BRHA 3EU0A 3QCCA 1KAVA 1Q6TA 1FGSA 1L8KA 2QCTA 3MVNA 4RDDA 2SHPA 5KA8A 3QCBA 2JFGA 1OHDA 1FPZA 2VTEA 3QCIA 5KA1A 2PA5A 1Q6JA 3B7OA 3OLRA 5KA0A 3QCDA 3EMUA 1YTSA 1YZ4A 2P6XA 1QZ0A 1W78A 1YPTA 1U25A 3GXHA 1QXKA 1PH0A 2H04A 5BUGA 2AZRA 5BX1A 2VEYA 2FH7A 2WJPA 1V3AA 2Y66A 3V0IA 1WCHA 2VOSA 1OEUA 3QCJA 4JMJA 4Y14A 4WU3A 2GWOA 1OEVA 3PYZA 4UAGA 2CNIA 2I6PA 3D42A 2I4EA 4WOHA 1PXHA 2AM1A 2Y67A 1T48A 2I4GA 2NZ6A 4JMKA 4ICZA 3V0FA 2WTZA 1ZCKA 2VORA 3I80A 1J6UA 1YGRA 1PTUA 4BUBA 2HC2A 1C83A 3HN7A 1A5YA 2DXPA 5KA9A 5A5EA 2I6OA 3V0DA 1XBOA 3F41A 2I5XA 4QDIA 2CJZA 1PTYA 2QDPA 1GG4A 4OHDA 2Y68A 1E8CA 5EHPA 5KADA 2BIJA 4WU2A 4JNBA 4NWGA 3MOZA 2JJDA 1NWEA 2B3OA 1OESA 1T4JA 2CNHA 5K24A 2CNGA 5KAAA 2I1YA 4RH9A 2XJAA 3MOWA 2QBSA 4QAPA 4NNDA 4J51A 4R0SA 2BV5A 3F9BA 5K25A 4ZN5A 2HCMA 1G1FA 1L8GA 2PBNA 1YGUA 1PA9A 1LQFA 1GFYA 4QUMA 1RXDA 2F6WA 1C85A 2IMGA 3N2AA 2J16B 1OEOX 5KACA 2VEUA 1Q6PA 4AZ1A 2H03A 1I9TA 2VEVA 3I7ZA 3V0JA 1R6HA 2WGPA 2VEWA 1X24A 5I6VA 4OHLA 5K9VA 4WTYA 4Y2EA 1G1HA 3QCZA 1BZHA 4PYHA 5HDEA 3MMJA 1I9SA 1EEHA 3V0HA 5A5FA 3QKPA 5LXQB 1VHRA 2GCAA 1XM2A 3UAGA 4HV4A 1MKPA 4GE6A 4ERCA 3QCHA 3O5XA 3F9AA 2QDCA 2OOQA 2I4HA 1J4XA 3O4SA 1WAXA 1Q1MA 2B4UA 2QDMA 4GS0A 3QCKA 1AAXA 4YR8B 2NV5A 3ZM2A 2I75A 3ZL8A 1OETA 4ZRTA 3V0EA 1G1GA 4QUNA 3QCFA 3A5KA 1YTNA 1OHEA 2UAGA 2UUPA 2QCJA 3BLUA 1GWZA 1U26A 1ZZWA 2HXPA 1ZCLA 3AWFA 1ZC0A 3S3FA 1P15A 1RPMA 2CNEA 3CM3A 2F6TA 2PSZA 2F6YA 4TVVA 4IKCA 4BUCA 2JFHA 3AWGA 4H1OA 2VEXA 2I3RA 1E0DA 2F6FA 2B4SA 3D9CA 4QBWA 4C13A 2F6ZA 3EAXA 2HY3A 5IBMA 4RH5A 4CVLA 1EEOA 2AHSA 2GP0A 1NNYA 4RI4A 1XRIA 5IBSA 2M3VA 1PTTA 2H4GA 3RO1A 3BM8A 4GRZA 2ESBA 4RHGA 3SR9A 2GC6A 5EHRA 5KABA 2P4DA 2XPCA 5KA4A 1BZCA 2OC3A 3QCNA 2C7SA 1YFOA 2I6MA 3QCGA 3EB1A 2PI7A 2Y1OA 2NLKA 4CVMA 2J17A 5M43A 3O3LA 4DGXA 5GTJA 2G6ZA 1G4US 3V0GA 4D3RA 1G7FA 3M4UA 3S4EA 2CM2A 4OHEA 4D3QA 5MMZB 4ZIYA 1W7KA 1JBVA 1WRMA 2CFVA 3RGOA 3RZ2A 4GWFA 4YAAA 2ZN7A 4QBEA 3ZM1A 1JBWA 1PYNA 3NRSA 2HNQA 2CM7A 3ZM5A 4RKKA 1U24A 2F71A 3QCLA 3AWEA 1C86A 2UUOA 2GCBA 5KA3A 2VTDA 4R0TA 1P3DA 1ECVA 2A8BA 2HB1A 2NT7A 4NX8A 4NWFA 4BPCA 3S3KA 2PT0A 4R30A 2Y2FA 3QCEA 1GQYA 1YTWA 4S0GA 5BZZA 4KYQA 2RF6A 5KA7A 4HRFA 1XXPA 2I6IA 2NT2A 2Q47A 1NZ7A 3ZM0A 4GE2A 2H02A 3CWEA 2H4KA 1OHCA 2CMBA 4NYHA 2YDUA 4Z6BA 3S3EA 3QCMA 3NMEA 2QBPA 3ZV2A 1M3GA 3GXGA 1C84A 2B07A 1EENA 4I8NA 1LARA 1LYVA 2BZLA 2B4PA 2HC1A 2B4OA 5J8RA 1C88A 3OMHA 5K9WA 1G4WR 1G7GA 2E0TA 4RI5A 3O4UA 1Q6NA 2H4VA 2QBQA 3D1HA 2GJTA 2QEPA 3A5JA 4HJPA 2I6JA 4QF5A 4KI9A 3ZMPA 1GQQA 5K22A 1FPRA 1XXVA 3SMEA 5K23A 1NO6A 1KAKA 4PVGA 3S4OA
chains in the Genus database with same CATH topology
3QKQA 5BZXA 1T49A 3D1QA 2I42A 2C46A 1PTVA 2CM8A 2CMAA 2MBCA 4ZI4A 1Q6MA 2J16A 1YN9A 5AWXA 3I36A 2G59A 3RGQA 1NWLA 3ZMQA 2Q05A 2HVLA 1FQ1A 4KYRA 1PA1A 3EZZA 2PQ5A 4GRYA 2R0BA 3BLTA 2I3UA 1D5RA 3PS5A 2OZ5A 1ONZA 3U96A 4H34A 4OHIA 4GFVA 1Q6SA 2BGDA 4MBBA 1C87A 2BGEA 4DGPA 1JLNA 3N0AA 3LJ8A 3S3HA 4JBCA 2Y96A 4GFUA 5KA2A 2FJMA 4BJOA 1I57A 3D1OA 2HNPA 2CM3A 2F46A 2FJNA 2A3KA 4QAHA 1OEMX 3D44A 2NTAA 3F81A 4GE5A 3F99A 3H2XA 1SUGA 1JF7A 2QBRA 2CMCA 1ONYA 1BZJA 2F70A 2OUDA 4OHHA 3ZM3A 2B49A 1YWFA 3O4TA 4B04A 2F6VA 2ZMMA 1NL9A 4D3PA 4HJQA 2CNFA 3BRHA 3EU0A 3QCCA 1KAVA 1Q6TA 1L8KA 2QCTA 4RDDA 2SHPA 5KA8A 3QCBA 1OHDA 1FPZA 3QCIA 5KA1A 2PA5A 1Q6JA 3B7OA 3OLRA 5KA0A 3QCDA 3EMUA 1YTSA 1YZ4A 2P6XA 1QZ0A 1YPTA 1U25A 3GXHA 1QXKA 1PH0A 2H04A 5BUGA 2AZRA 5BX1A 2VEYA 2FH7A 1V3AA 3V0IA 1WCHA 1OEUA 3QCJA 4JMJA 4Y14A 4WU3A 2GWOA 1OEVA 2CNIA 2I6PA 3D42A 2I4EA 4WOHA 1PXHA 1T48A 2I4GA 2NZ6A 4JMKA 4ICZA 3V0FA 1ZCKA 3I80A 1YGRA 1PTUA 2HC2A 1C83A 5KA9A 1A5YA 2DXPA 2I6OA 3V0DA 1XBOA 3F41A 2I5XA 2CJZA 1PTYA 2QDPA 4OHDA 5EHPA 5KADA 2BIJA 4WU2A 4JNBA 4NWGA 3MOZA 2JJDA 1NWEA 2B3OA 1OESA 1T4JA 2CNHA 5K24A 2CNGA 5KAAA 2I1YA 4RH9A 3MOWA 2QBSA 4QAPA 4NNDA 4J51A 4R0SA 2BV5A 3F9BA 5K25A 4ZN5A 2HCMA 1G1FA 1L8GA 2PBNA 1YGUA 1PA9A 1LQFA 1GFYA 4QUMA 1RXDA 2F6WA 1C85A 2IMGA 2J16B 1OEOX 5KACA 2VEUA 1Q6PA 4AZ1A 2H03A 1I9TA 2VEVA 3I7ZA 3V0JA 1R6HA 2WGPA 2VEWA 1X24A 5I6VA 4OHLA 5K9VA 4WTYA 4Y2EA 1G1HA 4PYHA 1BZHA 5HDEA 3MMJA 1I9SA 3V0HA 3QKPA 5LXQB 1VHRA 1XM2A 1MKPA 4GE6A 4ERCA 3QCHA 3O5XA 3F9AA 2QDCA 2OOQA 2I4HA 1J4XA 3O4SA 1WAXA 1Q1MA 2B4UA 2QDMA 4GS0A 3QCKA 1AAXA 4YR8B 2NV5A 3ZM2A 2I75A 1OETA 4ZRTA 3V0EA 1G1GA 4QUNA 3QCFA 3A5KA 1YTNA 1OHEA 2QCJA 3BLUA 1GWZA 1U26A 1ZZWA 2HXPA 1ZCLA 3AWFA 1ZC0A 3S3FA 1P15A 1RPMA 2CNEA 3CM3A 2F6TA 2PSZA 2F6YA 4TVVA 4IKCA 3AWGA 4H1OA 2VEXA 2I3RA 2F6FA 2B4SA 3D9CA 4QBWA 2F6ZA 3EAXA 2HY3A 5IBMA 4RH5A 1EEOA 2AHSA 2GP0A 1NNYA 4RI4A 1XRIA 5IBSA 2M3VA 1PTTA 2H4GA 3RO1A 3BM8A 4GRZA 2ESBA 4RHGA 3SR9A 5EHRA 5KABA 2P4DA 5KA4A 1BZCA 2OC3A 3QCNA 2C7SA 1YFOA 2I6MA 3QCGA 3EB1A 2PI7A 2NLKA 2J17A 5M43A 3O3LA 4DGXA 5GTJA 2G6ZA 1G4US 3V0GA 4D3RA 1G7FA 3M4UA 3S4EA 2CM2A 4OHEA 4D3QA 5MMZB 1WRMA 2CFVA 3RGOA 3RZ2A 4GWFA 4YAAA 2ZN7A 4QBEA 3ZM1A 1PYNA 2HNQA 2CM7A 4RKKA 1U24A 2F71A 3QCLA 3AWEA 1C86A 5KA3A 4R0TA 1ECVA 2A8BA 2HB1A 2NT7A 4NX8A 4NWFA 4BPCA 3S3KA 2PT0A 4R30A 2Y2FA 3QCEA 1YTWA 4S0GA 5BZZA 4KYQA 2RF6A 5KA7A 4HRFA 1XXPA 2I6IA 2NT2A 2Q47A 1NZ7A 3ZM0A 4GE2A 2H02A 3CWEA 2H4KA 1OHCA 2CMBA 4NYHA 2YDUA 4Z6BA 3S3EA 3QCMA 3NMEA 2QBPA 3ZV2A 1M3GA 3GXGA 1C84A 2B07A 1EENA 4I8NA 1LARA 1LYVA 2BZLA 2B4PA 2HC1A 2B4OA 5J8RA 1C88A 3OMHA 5K9WA 1G4WR 1G7GA 2E0TA 4RI5A 3O4UA 1Q6NA 2H4VA 2QBQA 3D1HA 2GJTA 2QEPA 3A5JA 4HJPA 2I6JA 4KI9A 3ZMPA 5K22A 1FPRA 1XXVA 3SMEA 5K23A 1NO6A 1KAKA 4PVGA 3S4OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QKQ A;  5BZX A;  1T49 A;  3D1Q A;  2I42 A;  2C46 A;  1PTV A;  2CM8 A;  2CMA A;  2MBC A;  4ZI4 A;  1Q6M A;  2J16 A;  1YN9 A;  5AWX A;  3I36 A;  2G59 A;  3RGQ A;  1NWL A;  3ZMQ A;  2Q05 A;  2HVL A;  1FQ1 A;  4KYR A;  1PA1 A;  3EZZ A;  2PQ5 A;  4GRY A;  2R0B A;  3BLT A;  2I3U A;  1D5R A;  3PS5 A;  2OZ5 A;  1ONZ A;  3U96 A;  4H34 A;  4OHI A;  4GFV A;  1Q6S A;  2BGD A;  4MBB A;  1C87 A;  2BGE A;  4DGP A;  1JLN A;  3N0A A;  3LJ8 A;  3S3H A;  4JBC A;  2Y96 A;  4GFU A;  5KA2 A;  2FJM A;  4BJO A;  1I57 A;  3D1O A;  2HNP A;  2CM3 A;  2F46 A;  2FJN A;  2A3K A;  4QAH A;  1OEM X;  3D44 A;  2NTA A;  3F81 A;  4GE5 A;  3F99 A;  3H2X A;  1SUG A;  1JF7 A;  2QBR A;  2CMC A;  1ONY A;  1BZJ A;  2F70 A;  2OUD A;  4OHH A;  3ZM3 A;  2B49 A;  1YWF A;  3O4T A;  4B04 A;  2F6V A;  2ZMM A;  1NL9 A;  4D3P A;  4HJQ A;  2CNF A;  3BRH A;  3EU0 A;  3QCC A;  1KAV A;  1Q6T A;  1L8K A;  2QCT A;  4RDD A;  2SHP A;  5KA8 A;  3QCB A;  1OHD A;  1FPZ A;  3QCI A;  5KA1 A;  2PA5 A;  1Q6J A;  3B7O A;  3OLR A;  5KA0 A;  3QCD A;  3EMU A;  1YTS A;  1YZ4 A;  2P6X A;  1QZ0 A;  1YPT A;  1U25 A;  3GXH A;  1QXK A;  1PH0 A;  2H04 A;  5BUG A;  2AZR A;  5BX1 A;  2VEY A;  2FH7 A;  1V3A A;  3V0I A;  1WCH A;  1OEU A;  3QCJ A;  4JMJ A;  4Y14 A;  4WU3 A;  2GWO A;  1OEV A;  2CNI A;  2I6P A;  3D42 A;  2I4E A;  4WOH A;  1PXH A;  1T48 A;  2I4G A;  2NZ6 A;  4JMK A;  4ICZ A;  3V0F A;  1ZCK A;  3I80 A;  1YGR A;  1PTU A;  2HC2 A;  1C83 A;  5KA9 A;  1A5Y A;  2DXP A;  2I6O A;  3V0D A;  1XBO A;  3F41 A;  2I5X A;  2CJZ A;  1PTY A;  2QDP A;  4OHD A;  5EHP A;  5KAD A;  2BIJ A;  4WU2 A;  4JNB A;  4NWG A;  3MOZ A;  2JJD A;  1NWE A;  2B3O A;  1OES A;  1T4J A;  2CNH A;  5K24 A;  2CNG A;  5KAA A;  2I1Y A;  4RH9 A;  3MOW A;  2QBS A;  4QAP A;  4NND A;  4J51 A;  4R0S A;  2BV5 A;  3F9B A;  5K25 A;  4ZN5 A;  2HCM A;  1G1F A;  1L8G A;  2PBN A;  1YGU A;  1PA9 A;  1LQF A;  1GFY A;  4QUM A;  1RXD A;  2F6W A;  1C85 A;  2IMG A;  2J16 B;  1OEO X;  5KAC A;  2VEU A;  1Q6P A;  4AZ1 A;  2H03 A;  1I9T A;  2VEV A;  3I7Z A;  3V0J A;  1R6H A;  2WGP A;  2VEW A;  1X24 A;  5I6V A;  4OHL A;  5K9V A;  4WTY A;  4Y2E A;  1G1H A;  4PYH A;  1BZH A;  5HDE A;  3MMJ A;  1I9S A;  3V0H A;  3QKP A;  5LXQ B;  1VHR A;  1XM2 A;  1MKP A;  4GE6 A;  4ERC A;  3QCH A;  3O5X A;  3F9A A;  2QDC A;  2OOQ A;  2I4H A;  1J4X A;  3O4S A;  1WAX A;  1Q1M A;  2B4U A;  2QDM A;  4GS0 A;  3QCK A;  1AAX A;  4YR8 B;  2NV5 A;  3ZM2 A;  2I75 A;  1OET A;  4ZRT A;  3V0E A;  1G1G A;  4QUN A;  3QCF A;  3A5K A;  1YTN A;  1OHE A;  2QCJ A;  3BLU A;  1GWZ A;  1U26 A;  1ZZW A;  2HXP A;  1ZCL A;  3AWF A;  1ZC0 A;  3S3F A;  1P15 A;  1RPM A;  2CNE A;  3CM3 A;  2F6T A;  2PSZ A;  2F6Y A;  4TVV A;  4IKC A;  3AWG A;  4H1O A;  2VEX A;  2I3R A;  2F6F A;  2B4S A;  3D9C A;  4QBW A;  2F6Z A;  3EAX A;  2HY3 A;  5IBM A;  4RH5 A;  1EEO A;  2AHS A;  2GP0 A;  1NNY A;  4RI4 A;  1XRI A;  5IBS A;  2M3V A;  1PTT A;  2H4G A;  3RO1 A;  3BM8 A;  4GRZ A;  2ESB A;  4RHG A;  3SR9 A;  5EHR A;  5KAB A;  2P4D A;  5KA4 A;  1BZC A;  2OC3 A;  3QCN A;  2C7S A;  1YFO A;  2I6M A;  3QCG A;  3EB1 A;  2PI7 A;  2NLK A;  2J17 A;  5M43 A;  3O3L A;  4DGX A;  5GTJ A;  2G6Z A;  1G4U S;  3V0G A;  4D3R A;  1G7F A;  3M4U A;  3S4E A;  2CM2 A;  4OHE A;  4D3Q A;  5MMZ B;  1WRM A;  2CFV A;  3RGO A;  3RZ2 A;  4GWF A;  4YAA A;  2ZN7 A;  4QBE A;  3ZM1 A;  1PYN A;  2HNQ A;  2CM7 A;  4RKK A;  1U24 A;  2F71 A;  3QCL A;  3AWE A;  1C86 A;  5KA3 A;  4R0T A;  1ECV A;  2A8B A;  2HB1 A;  2NT7 A;  4NX8 A;  4NWF A;  4BPC A;  3S3K A;  2PT0 A;  4R30 A;  2Y2F A;  3QCE A;  1YTW A;  4S0G A;  5BZZ A;  4KYQ A;  2RF6 A;  5KA7 A;  4HRF A;  1XXP A;  2I6I A;  2NT2 A;  2Q47 A;  1NZ7 A;  3ZM0 A;  4GE2 A;  2H02 A;  3CWE A;  2H4K A;  1OHC A;  2CMB A;  4NYH A;  2YDU A;  4Z6B A;  3S3E A;  3QCM A;  3NME A;  2QBP A;  3ZV2 A;  1M3G A;  3GXG A;  1C84 A;  2B07 A;  1EEN A;  4I8N A;  1LAR A;  1LYV A;  2BZL A;  2B4P A;  2HC1 A;  2B4O A;  5J8R A;  1C88 A;  3OMH A;  5K9W A;  1G4W R;  1G7G A;  2E0T A;  4RI5 A;  3O4U A;  1Q6N A;  2H4V A;  2QBQ A;  3D1H A;  2GJT A;  2QEP A;  3A5J A;  4HJP A;  2I6J A;  4KI9 A;  3ZMP A;  5K22 A;  1FPR A;  1XXV A;  3SME A;  5K23 A;  1NO6 A;  1KAK A;  4PVG A;  3S4O A; 
#chains in the Genus database with same CATH topology
 2GC5 A;  3QKQ A;  5BZX A;  1T49 A;  3D1Q A;  2I42 A;  2C46 A;  1PTV A;  2CM8 A;  2JFF A;  4CVK A;  2F00 A;  2CMA A;  2MBC A;  4ZI4 A;  1Q6M A;  2J16 A;  1YN9 A;  5AWX A;  3I36 A;  2G59 A;  3RGQ A;  1NWL A;  3ZMQ A;  1O5Z A;  2HVL A;  2Q05 A;  1FQ1 A;  4KYR A;  1PA1 A;  3EZZ A;  2PQ5 A;  4GRY A;  2R0B A;  3BLT A;  2I3U A;  1D5R A;  3PS5 A;  2OZ5 A;  1ONZ A;  2X5O A;  3U96 A;  1P31 A;  4H34 A;  4OHI A;  4GFV A;  3LK7 A;  1Q6S A;  2BGD A;  2AM2 A;  4MBB A;  1C87 A;  2BGE A;  4DGP A;  1JLN A;  3ZM6 A;  3N0A A;  3LJ8 A;  3S3H A;  4JBC A;  2Y96 A;  4C12 A;  4GFU A;  5KA2 A;  2FJM A;  4BJO A;  1I57 A;  3D1O A;  2HNP A;  2CM3 A;  2F46 A;  2FJN A;  2A3K A;  4QAH A;  1OEM X;  3D44 A;  2NTA A;  3F81 A;  4GE5 A;  3F99 A;  1UAG A;  3H2X A;  1SUG A;  1JF7 A;  2QBR A;  2CMC A;  1ONY A;  1BZJ A;  2F70 A;  2OUD A;  4OHH A;  3ZM3 A;  2B49 A;  1YWF A;  3O4T A;  4B04 A;  2F6V A;  2ZMM A;  1NL9 A;  4D3P A;  4HJQ A;  2CNF A;  3BRH A;  3EU0 A;  3QCC A;  1KAV A;  1Q6T A;  1FGS A;  1L8K A;  2QCT A;  3MVN A;  4RDD A;  2SHP A;  5KA8 A;  3QCB A;  2JFG A;  1OHD A;  1FPZ A;  2VTE A;  3QCI A;  5KA1 A;  2PA5 A;  1Q6J A;  3B7O A;  3OLR A;  5KA0 A;  3QCD A;  3EMU A;  1YTS A;  1YZ4 A;  2P6X A;  1QZ0 A;  1W78 A;  1YPT A;  1U25 A;  3GXH A;  1QXK A;  1PH0 A;  2H04 A;  5BUG A;  2AZR A;  5BX1 A;  2VEY A;  2FH7 A;  2WJP A;  1V3A A;  2Y66 A;  3V0I A;  1WCH A;  2VOS A;  1OEU A;  3QCJ A;  4JMJ A;  4Y14 A;  4WU3 A;  2GWO A;  1OEV A;  3PYZ A;  4UAG A;  2CNI A;  2I6P A;  3D42 A;  2I4E A;  4WOH A;  1PXH A;  2AM1 A;  2Y67 A;  1T48 A;  2I4G A;  2NZ6 A;  4JMK A;  4ICZ A;  3V0F A;  2WTZ A;  1ZCK A;  2VOR A;  3I80 A;  1J6U A;  1YGR A;  1PTU A;  4BUB A;  2HC2 A;  1C83 A;  3HN7 A;  1A5Y A;  2DXP A;  5KA9 A;  5A5E A;  2I6O A;  3V0D A;  1XBO A;  3F41 A;  2I5X A;  4QDI A;  2CJZ A;  1PTY A;  2QDP A;  1GG4 A;  4OHD A;  2Y68 A;  1E8C A;  5EHP A;  5KAD A;  2BIJ A;  4WU2 A;  4JNB A;  4NWG A;  3MOZ A;  2JJD A;  1NWE A;  2B3O A;  1OES A;  1T4J A;  2CNH A;  5K24 A;  2CNG A;  5KAA A;  2I1Y A;  4RH9 A;  2XJA A;  3MOW A;  2QBS A;  4QAP A;  4NND A;  4J51 A;  4R0S A;  2BV5 A;  3F9B A;  5K25 A;  4ZN5 A;  2HCM A;  1G1F A;  1L8G A;  2PBN A;  1YGU A;  1PA9 A;  1LQF A;  1GFY A;  4QUM A;  1RXD A;  2F6W A;  1C85 A;  2IMG A;  3N2A A;  2J16 B;  1OEO X;  5KAC A;  2VEU A;  1Q6P A;  4AZ1 A;  2H03 A;  1I9T A;  2VEV A;  3I7Z A;  3V0J A;  1R6H A;  2WGP A;  2VEW A;  1X24 A;  5I6V A;  4OHL A;  5K9V A;  4WTY A;  4Y2E A;  1G1H A;  3QCZ A;  1BZH A;  4PYH A;  5HDE A;  3MMJ A;  1I9S A;  1EEH A;  3V0H A;  5A5F A;  3QKP A;  5LXQ B;  1VHR A;  2GCA A;  1XM2 A;  3UAG A;  4HV4 A;  1MKP A;  4GE6 A;  4ERC A;  3QCH A;  3O5X A;  3F9A A;  2QDC A;  2OOQ A;  2I4H A;  1J4X A;  3O4S A;  1WAX A;  1Q1M A;  2B4U A;  2QDM A;  4GS0 A;  3QCK A;  1AAX A;  4YR8 B;  2NV5 A;  3ZM2 A;  2I75 A;  3ZL8 A;  1OET A;  4ZRT A;  3V0E A;  1G1G A;  4QUN A;  3QCF A;  3A5K A;  1YTN A;  1OHE A;  2UAG A;  2UUP A;  2QCJ A;  3BLU A;  1GWZ A;  1U26 A;  1ZZW A;  2HXP A;  1ZCL A;  3AWF A;  1ZC0 A;  3S3F A;  1P15 A;  1RPM A;  2CNE A;  3CM3 A;  2F6T A;  2PSZ A;  2F6Y A;  4TVV A;  4IKC A;  4BUC A;  2JFH A;  3AWG A;  4H1O A;  2VEX A;  2I3R A;  1E0D A;  2F6F A;  2B4S A;  3D9C A;  4QBW A;  4C13 A;  2F6Z A;  3EAX A;  2HY3 A;  5IBM A;  4RH5 A;  4CVL A;  1EEO A;  2AHS A;  2GP0 A;  1NNY A;  4RI4 A;  1XRI A;  5IBS A;  2M3V A;  1PTT A;  2H4G A;  3RO1 A;  3BM8 A;  4GRZ A;  2ESB A;  4RHG A;  3SR9 A;  2GC6 A;  5EHR A;  5KAB A;  2P4D A;  2XPC A;  5KA4 A;  1BZC A;  2OC3 A;  3QCN A;  2C7S A;  1YFO A;  2I6M A;  3QCG A;  3EB1 A;  2PI7 A;  2Y1O A;  2NLK A;  4CVM A;  2J17 A;  5M43 A;  3O3L A;  4DGX A;  5GTJ A;  2G6Z A;  1G4U S;  3V0G A;  4D3R A;  1G7F A;  3M4U A;  3S4E A;  2CM2 A;  4OHE A;  4D3Q A;  5MMZ B;  4ZIY A;  1W7K A;  1JBV A;  1WRM A;  2CFV A;  3RGO A;  3RZ2 A;  4GWF A;  4YAA A;  2ZN7 A;  4QBE A;  3ZM1 A;  1JBW A;  1PYN A;  3NRS A;  2HNQ A;  2CM7 A;  3ZM5 A;  4RKK A;  1U24 A;  2F71 A;  3QCL A;  3AWE A;  1C86 A;  2UUO A;  2GCB A;  5KA3 A;  2VTD A;  4R0T A;  1P3D A;  1ECV A;  2A8B A;  2HB1 A;  2NT7 A;  4NX8 A;  4NWF A;  4BPC A;  3S3K A;  2PT0 A;  4R30 A;  2Y2F A;  3QCE A;  1GQY A;  1YTW A;  4S0G A;  5BZZ A;  4KYQ A;  2RF6 A;  5KA7 A;  4HRF A;  1XXP A;  2I6I A;  2NT2 A;  2Q47 A;  1NZ7 A;  3ZM0 A;  4GE2 A;  2H02 A;  3CWE A;  2H4K A;  1OHC A;  2CMB A;  4NYH A;  2YDU A;  4Z6B A;  3S3E A;  3QCM A;  3NME A;  2QBP A;  3ZV2 A;  1M3G A;  3GXG A;  1C84 A;  2B07 A;  1EEN A;  4I8N A;  1LAR A;  1LYV A;  2BZL A;  2B4P A;  2HC1 A;  2B4O A;  5J8R A;  1C88 A;  3OMH A;  5K9W A;  1G4W R;  1G7G A;  2E0T A;  4RI5 A;  3O4U A;  1Q6N A;  2H4V A;  2QBQ A;  3D1H A;  2GJT A;  2QEP A;  3A5J A;  4HJP A;  2I6J A;  4QF5 A;  4KI9 A;  3ZMP A;  1GQQ A;  5K22 A;  1FPR A;  1XXV A;  3SME A;  5K23 A;  1NO6 A;  1KAK A;  4PVG A;  3S4O A; 
#chains in the Genus database with same CATH homology
 3QKQ A;  5BZX A;  1T49 A;  3D1Q A;  2I42 A;  2C46 A;  1PTV A;  2CM8 A;  2CMA A;  2MBC A;  4ZI4 A;  1Q6M A;  2J16 A;  1YN9 A;  5AWX A;  3I36 A;  2G59 A;  3RGQ A;  1NWL A;  3ZMQ A;  2Q05 A;  2HVL A;  1FQ1 A;  4KYR A;  1PA1 A;  3EZZ A;  2PQ5 A;  4GRY A;  2R0B A;  3BLT A;  2I3U A;  1D5R A;  3PS5 A;  2OZ5 A;  1ONZ A;  3U96 A;  4H34 A;  4OHI A;  4GFV A;  1Q6S A;  2BGD A;  4MBB A;  1C87 A;  2BGE A;  4DGP A;  1JLN A;  3N0A A;  3LJ8 A;  3S3H A;  4JBC A;  2Y96 A;  4GFU A;  5KA2 A;  2FJM A;  4BJO A;  1I57 A;  3D1O A;  2HNP A;  2CM3 A;  2F46 A;  2FJN A;  2A3K A;  4QAH A;  1OEM X;  3D44 A;  2NTA A;  3F81 A;  4GE5 A;  3F99 A;  3H2X A;  1SUG A;  1JF7 A;  2QBR A;  2CMC A;  1ONY A;  1BZJ A;  2F70 A;  2OUD A;  4OHH A;  3ZM3 A;  2B49 A;  1YWF A;  3O4T A;  4B04 A;  2F6V A;  2ZMM A;  1NL9 A;  4D3P A;  4HJQ A;  2CNF A;  3BRH A;  3EU0 A;  3QCC A;  1KAV A;  1Q6T A;  1L8K A;  2QCT A;  4RDD A;  2SHP A;  5KA8 A;  3QCB A;  1OHD A;  1FPZ A;  3QCI A;  5KA1 A;  2PA5 A;  1Q6J A;  3B7O A;  3OLR A;  5KA0 A;  3QCD A;  3EMU A;  1YTS A;  1YZ4 A;  2P6X A;  1QZ0 A;  1YPT A;  1U25 A;  3GXH A;  1QXK A;  1PH0 A;  2H04 A;  5BUG A;  2AZR A;  5BX1 A;  2VEY A;  2FH7 A;  1V3A A;  3V0I A;  1WCH A;  1OEU A;  3QCJ A;  4JMJ A;  4Y14 A;  4WU3 A;  2GWO A;  1OEV A;  2CNI A;  2I6P A;  3D42 A;  2I4E A;  4WOH A;  1PXH A;  1T48 A;  2I4G A;  2NZ6 A;  4JMK A;  4ICZ A;  3V0F A;  1ZCK A;  3I80 A;  1YGR A;  1PTU A;  2HC2 A;  1C83 A;  5KA9 A;  1A5Y A;  2DXP A;  2I6O A;  3V0D A;  1XBO A;  3F41 A;  2I5X A;  2CJZ A;  1PTY A;  2QDP A;  4OHD A;  5EHP A;  5KAD A;  2BIJ A;  4WU2 A;  4JNB A;  4NWG A;  3MOZ A;  2JJD A;  1NWE A;  2B3O A;  1OES A;  1T4J A;  2CNH A;  5K24 A;  2CNG A;  5KAA A;  2I1Y A;  4RH9 A;  3MOW A;  2QBS A;  4QAP A;  4NND A;  4J51 A;  4R0S A;  2BV5 A;  3F9B A;  5K25 A;  4ZN5 A;  2HCM A;  1G1F A;  1L8G A;  2PBN A;  1YGU A;  1PA9 A;  1LQF A;  1GFY A;  4QUM A;  1RXD A;  2F6W A;  1C85 A;  2IMG A;  2J16 B;  1OEO X;  5KAC A;  2VEU A;  1Q6P A;  4AZ1 A;  2H03 A;  1I9T A;  2VEV A;  3I7Z A;  3V0J A;  1R6H A;  2WGP A;  2VEW A;  1X24 A;  5I6V A;  4OHL A;  5K9V A;  4WTY A;  4Y2E A;  1G1H A;  4PYH A;  1BZH A;  5HDE A;  3MMJ A;  1I9S A;  3V0H A;  3QKP A;  5LXQ B;  1VHR A;  1XM2 A;  1MKP A;  4GE6 A;  4ERC A;  3QCH A;  3O5X A;  3F9A A;  2QDC A;  2OOQ A;  2I4H A;  1J4X A;  3O4S A;  1WAX A;  1Q1M A;  2B4U A;  2QDM A;  4GS0 A;  3QCK A;  1AAX A;  4YR8 B;  2NV5 A;  3ZM2 A;  2I75 A;  1OET A;  4ZRT A;  3V0E A;  1G1G A;  4QUN A;  3QCF A;  3A5K A;  1YTN A;  1OHE A;  2QCJ A;  3BLU A;  1GWZ A;  1U26 A;  1ZZW A;  2HXP A;  1ZCL A;  3AWF A;  1ZC0 A;  3S3F A;  1P15 A;  1RPM A;  2CNE A;  3CM3 A;  2F6T A;  2PSZ A;  2F6Y A;  4TVV A;  4IKC A;  3AWG A;  4H1O A;  2VEX A;  2I3R A;  2F6F A;  2B4S A;  3D9C A;  4QBW A;  2F6Z A;  3EAX A;  2HY3 A;  5IBM A;  4RH5 A;  1EEO A;  2AHS A;  2GP0 A;  1NNY A;  4RI4 A;  1XRI A;  5IBS A;  2M3V A;  1PTT A;  2H4G A;  3RO1 A;  3BM8 A;  4GRZ A;  2ESB A;  4RHG A;  3SR9 A;  5EHR A;  5KAB A;  2P4D A;  5KA4 A;  1BZC A;  2OC3 A;  3QCN A;  2C7S A;  1YFO A;  2I6M A;  3QCG A;  3EB1 A;  2PI7 A;  2NLK A;  2J17 A;  5M43 A;  3O3L A;  4DGX A;  5GTJ A;  2G6Z A;  1G4U S;  3V0G A;  4D3R A;  1G7F A;  3M4U A;  3S4E A;  2CM2 A;  4OHE A;  4D3Q A;  5MMZ B;  1WRM A;  2CFV A;  3RGO A;  3RZ2 A;  4GWF A;  4YAA A;  2ZN7 A;  4QBE A;  3ZM1 A;  1PYN A;  2HNQ A;  2CM7 A;  4RKK A;  1U24 A;  2F71 A;  3QCL A;  3AWE A;  1C86 A;  5KA3 A;  4R0T A;  1ECV A;  2A8B A;  2HB1 A;  2NT7 A;  4NX8 A;  4NWF A;  4BPC A;  3S3K A;  2PT0 A;  4R30 A;  2Y2F A;  3QCE A;  1YTW A;  4S0G A;  5BZZ A;  4KYQ A;  2RF6 A;  5KA7 A;  4HRF A;  1XXP A;  2I6I A;  2NT2 A;  2Q47 A;  1NZ7 A;  3ZM0 A;  4GE2 A;  2H02 A;  3CWE A;  2H4K A;  1OHC A;  2CMB A;  4NYH A;  2YDU A;  4Z6B A;  3S3E A;  3QCM A;  3NME A;  2QBP A;  3ZV2 A;  1M3G A;  3GXG A;  1C84 A;  2B07 A;  1EEN A;  4I8N A;  1LAR A;  1LYV A;  2BZL A;  2B4P A;  2HC1 A;  2B4O A;  5J8R A;  1C88 A;  3OMH A;  5K9W A;  1G4W R;  1G7G A;  2E0T A;  4RI5 A;  3O4U A;  1Q6N A;  2H4V A;  2QBQ A;  3D1H A;  2GJT A;  2QEP A;  3A5J A;  4HJP A;  2I6J A;  4KI9 A;  3ZMP A;  5K22 A;  1FPR A;  1XXV A;  3SME A;  5K23 A;  1NO6 A;  1KAK A;  4PVG A;  3S4O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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