2H04A

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
291
structure length
280
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein tyrosine phosphatase, receptor type, B,
total genus 103
structure length 280
sequence length 291
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2h04A00
4RI4A 1C85A 1FPRA 1BZCA 1EENA 1X24A 4B04A 1YPTA 2I1YA 2BIJA 4ZN5A 2OOQA 5M43A 3U96A 2NZ6A 3V0DA 1G7FA 1KAKA 3QCEA 3QCCA 2CNFA 4RKKA 2HC1A 4H34A 3RGQA 5KA8A 4JNBA 3S4EA 4NWFA 1R6HA 3QCBA 2I6PA 2J17A 2CNHA 3D44A 3S3EA 1PTYA 3S3HA 4R0SA 4KYQA 3V0GA 1I9SA 2F70A 4Y14A 1NNYA 1M3GA 2F6ZA 2H03A 3D9CA 1PTUA 1V3AA 1U26A 2QCTA 5KA7A 3QCKA 4JMKA 3ZV2A 5KA4A 2GJTA 3QCFA 1MKPA 2CMCA 1L8GA 3RGOA 5K9WA 2F6TA 1LARA 2F6WA 1ONYA 1EEOA 3AWEA 5EHPA 2VEXA 3QCGA 5IBSA 4OHLA 1XBOA 4D3RA 3I36A 2VEWA 2CNIA 1YWFA 2CMBA 3EAXA 1YN9A 3NMEA 2NT7A 4QUNA 4QAHA 5KACA 1C88A 1PH0A 5MMZB 4KI9A 2HXPA 2FH7A 5J8RA 3ZM1A 2AHSA 2ZN7A 2BV5A 4BJOA 3D42A 3F41A 3QCDA 3EB1A 4AZ1A 3EU0A 1PTVA 1Q6MA 2VEUA 3QCMA 3BLUA 2B4UA 3O3LA 1PA9A 2QBRA 1XXVA 3ZMPA 4YAAA 1RPMA 1QXKA 1GFYA 1G1HA 1T48A 3GXGA 3F9BA 2I6IA 5KA9A 3SR9A 1PA1A 2HCMA 4NNDA 1BZHA 2B3OA 3AWGA 5LXQB 1Q6NA 2F6YA 2FJNA 3BRHA 2B07A 1C84A 2PBNA 4JBCA 3ZM3A 4WTYA 3V0JA 2F71A 3LJ8A 2I6MA 4RDDA 4HJPA 5KADA 2B4OA 5K22A 2BZLA 1GWZA 1I9TA 2P4DA 2ESBA 4TVVA 3MOZA 3N0AA 4Z6BA 3OLRA 1ZCKA 4DGXA 5GTJA 1YTSA 2YDUA 2CM2A 2J16B 4WU2A 2HNQA 3ZM0A 2QDPA 1OEOX 2B4SA 5I6VA 2BGEA 2I6JA 4R30A 2M3VA 5KA1A 1G4WR 1T49A 2J16A 3F9AA 2Y2FA 4D3PA 2PQ5A 2NTAA 1ZCLA 3MOWA 3D1QA 4PVGA 3BM8A 5K23A 4NX8A 4RI5A 3M4UA 2A3KA 1YTNA 2SHPA 4GWFA 4RHGA 1YGUA 2I3RA 4QUMA 2PI7A 4Y2EA 2NT2A 3B7OA 1OEVA 1OEUA 2HC2A 3H2XA 1FPZA 2GWOA 1QZ0A 4IKCA 3RO1A 5BX1A 4QBEA 5K24A 3O4UA 2CJZA 1PYNA 3O5XA 4OHIA 3EMUA 2JJDA 2F46A 1G7GA 5KAAA 2DXPA 1OETA 1ONZA 4I8NA 1U25A 1OEMX 4GFVA 2I4GA 2FJMA 2I4EA 3V0IA 2OC3A 2I75A 3AWFA 3F81A 1C86A 3QCJA 3EZZA 2PT0A 3QKPA 4NWGA 3I80A 3O4SA 1C87A 1WAXA 1NL9A 1Q6PA 1T4JA 2IMGA 2CNEA 1BZJA 1FQ1A 3ZM2A 4HRFA 2NV5A 2CFVA 3CWEA 3QCNA 4GE5A 5K9VA 1NZ7A 2Y96A 1J4XA 2NLKA 3SMEA 1PTTA 2I42A 1U24A 2HY3A 1Q6JA 3QKQA 2CNGA 1OHDA 1D5RA 1AAXA 3QCIA 2F6VA 1YGRA 2VEYA 5EHRA 1NO6A 1Q6SA 1ZC0A 2H4GA 1OESA 4HJQA 4H1OA 3MMJA 2H04A 2BGDA 5HDEA 4QAPA 3S3KA 4MBBA 2H4KA 2CM7A 2CM8A 4ICZA 2AZRA 2WGPA 5KA2A 1YFOA 2I3UA 1JLNA 2QDCA 1ECVA 4GRYA 3V0FA 2G59A 5KA3A 1ZZWA 1L8KA 4OHHA 1RXDA 2I4HA 2HNPA 3I7ZA 4R0TA 1LYVA 4RH5A 3F99A 4OHDA 3OMHA 2Q47A 3D1HA 3V0EA 1JF7A 1I57A 4GS0A 5BZXA 1WRMA 3S3FA 4J51A 1NWEA 5KA0A 1XM2A 4ZI4A 4BPCA 2CM3A 2QBQA 3S4OA 3QCHA 3GXHA 1A5YA 1WCHA 3A5KA 2OZ5A 1OHCA 1YTWA 4RH9A 1NWLA 4PYHA 4GFUA 2P6XA 2C46A 5BUGA 1PXHA 2CMAA 4WU3A 2H02A 1G4US 1G1FA 2Q05A 4QBWA 4WOHA 3V0HA 4OHEA 2QDMA 4NYHA 2PA5A 2H4VA 2R0BA 2HB1A 4DGPA 1XRIA 3BLTA 5AWXA 3CM3A 2B49A 3RZ2A 2MBCA 3D1OA 1KAVA 4D3QA 2A8BA 3O4TA 5KABA 1YZ4A 1G1GA 1Q1MA 2B4PA 1OHEA 2ZMMA 3PS5A 3ZMQA 2G6ZA 2OUDA 2I5XA 2GP0A 3QCLA 1C83A 1LQFA 4ZRTA 2F6FA 4YR8B 1XXPA 5IBMA 2QEPA 2VEVA 5BZZA 4JMJA 4KYRA 5K25A 1VHRA 2C7SA 2I6OA 4ERCA 2QBSA 1Q6TA 4GE6A 2RF6A 2QBPA 2HVLA 2PSZA 4S0GA 1P15A 2QCJA 3A5JA 2E0TA 4GRZA 1SUGA 4GE2A
chains in the Genus database with same CATH superfamily
4RI4A 1C85A 1FGSA 1FPRA 1BZCA 1EENA 1X24A 4BUCA 2JFGA 4B04A 1YPTA 2UUPA 2I1YA 2BIJA 4ZN5A 2OOQA 5M43A 3U96A 2AM2A 2NZ6A 3V0DA 1G7FA 1KAKA 3LK7A 3QCEA 3QCCA 2CNFA 4RKKA 2HC1A 4H34A 2Y1OA 3RGQA 5KA8A 4JNBA 3S4EA 4NWFA 1P3DA 2VORA 1R6HA 3QCBA 2I6PA 2J17A 2CNHA 3D44A 3S3EA 1PTYA 3UAGA 3S3HA 4R0SA 4KYQA 3V0GA 1I9SA 2F70A 4Y14A 3ZM6A 1NNYA 1M3GA 2F6ZA 2H03A 3D9CA 1PTUA 1V3AA 1U26A 2QCTA 5KA7A 3QCKA 4JMKA 3ZV2A 5KA4A 2GJTA 3QCFA 1MKPA 2CMCA 1L8GA 3RGOA 5K9WA 2F6TA 1LARA 2WJPA 2F6WA 1ONYA 1EEOA 3AWEA 2XPCA 5EHPA 2VEXA 3QCGA 5IBSA 4OHLA 1XBOA 4CVMA 4D3RA 3I36A 1JBWA 2VEWA 2CNIA 1YWFA 2CMBA 3EAXA 1YN9A 3NMEA 2NT7A 4QUNA 4QAHA 5KACA 1C88A 1PH0A 5MMZB 4KI9A 2HXPA 2FH7A 5J8RA 3ZM1A 2AHSA 2ZN7A 2BV5A 4BJOA 3D42A 3F41A 3QCDA 3EB1A 4AZ1A 3EU0A 1PTVA 1Q6MA 2VEUA 3QCMA 3BLUA 1W7KA 2B4UA 3O3LA 1PA9A 2JFHA 2QBRA 1XXVA 3ZMPA 4YAAA 1RPMA 1QXKA 1GFYA 2WTZA 2X5OA 1G1HA 4CVLA 1T48A 3GXGA 3F9BA 2I6IA 5KA9A 3SR9A 4HV4A 1PA1A 2HCMA 4NNDA 1BZHA 2B3OA 3AWGA 5LXQB 1Q6NA 2F6YA 2FJNA 3BRHA 2B07A 1C84A 2PBNA 4JBCA 3ZM3A 4WTYA 2GC6A 3V0JA 2F71A 3LJ8A 2I6MA 5A5EA 4RDDA 4HJPA 5KADA 4QF5A 2B4OA 5K22A 2BZLA 1GWZA 1I9TA 2P4DA 2ESBA 4TVVA 1UAGA 3MOZA 3N0AA 4Z6BA 3OLRA 1ZCKA 4DGXA 5GTJA 1YTSA 2YDUA 2CM2A 3MVNA 2J16B 4WU2A 2HNQA 3ZM0A 1W78A 1O5ZA 2QDPA 1OEOX 2B4SA 5I6VA 3PYZA 2BGEA 2I6JA 4R30A 2M3VA 5KA1A 1G4WR 1T49A 2J16A 3F9AA 2Y2FA 4D3PA 2PQ5A 2NTAA 1ZCLA 3MOWA 3D1QA 4PVGA 4C12A 3BM8A 5K23A 4NX8A 4CVKA 4RI5A 2VOSA 3M4UA 2A3KA 1YTNA 2SHPA 4GWFA 4RHGA 1YGUA 2I3RA 4QUMA 2PI7A 1JBVA 4Y2EA 1GG4A 2NT2A 3B7OA 1E0DA 2JFFA 1OEVA 1OEUA 2HC2A 3H2XA 1J6UA 1FPZA 2GWOA 1QZ0A 4IKCA 3RO1A 5BX1A 4QBEA 5K24A 3O4UA 2CJZA 1GQYA 1PYNA 3O5XA 4OHIA 3ZM5A 3EMUA 2JJDA 2F46A 1G7GA 5KAAA 2DXPA 1EEHA 1OETA 1ONZA 4I8NA 1U25A 1OEMX 4GFVA 2I4GA 2GCBA 2FJMA 2I4EA 3V0IA 2OC3A 2I75A 3AWFA 3F81A 1C86A 3QCJA 2VTDA 3EZZA 2PT0A 3QKPA 2Y68A 4NWGA 3I80A 3O4SA 1C87A 1WAXA 2Y66A 1NL9A 1Q6PA 1T4JA 2IMGA 2CNEA 1BZJA 1FQ1A 3ZM2A 4HRFA 2NV5A 2CFVA 3CWEA 3QCNA 4GE5A 3NRSA 4ZIYA 1NZ7A 5K9VA 2Y96A 1J4XA 2NLKA 3SMEA 5A5FA 3N2AA 1PTTA 2AM1A 2I42A 1U24A 2HY3A 1Q6JA 3QKQA 2CNGA 1OHDA 1D5RA 1AAXA 3QCIA 2F6VA 1YGRA 2VEYA 3ZL8A 5EHRA 4UAGA 1NO6A 1Q6SA 1ZC0A 2H4GA 1OESA 4C13A 4HJQA 4H1OA 3MMJA 2H04A 2BGDA 5HDEA 4QAPA 3S3KA 4MBBA 2H4KA 2CM7A 2CM8A 4ICZA 2AZRA 2WGPA 5KA2A 1YFOA 2I3UA 3HN7A 1JLNA 2QDCA 1ECVA 4GRYA 4QDIA 3V0FA 2G59A 5KA3A 1ZZWA 1L8KA 4OHHA 1RXDA 2I4HA 2HNPA 3I7ZA 4R0TA 1LYVA 4RH5A 3F99A 4OHDA 3OMHA 2Q47A 3D1HA 3V0EA 1JF7A 1I57A 4GS0A 5BZXA 1WRMA 3S3FA 4J51A 2GC5A 1NWEA 5KA0A 1XM2A 4ZI4A 4BPCA 2CM3A 2QBQA 3S4OA 3QCHA 3GXHA 1A5YA 1WCHA 3A5KA 2OZ5A 2UAGA 1OHCA 1YTWA 4RH9A 1NWLA 4PYHA 4GFUA 2P6XA 2C46A 5BUGA 1PXHA 2CMAA 4WU3A 1GQQA 2H02A 2GCAA 1G4US 1G1FA 2Q05A 4QBWA 4WOHA 3V0HA 4OHEA 2QDMA 4NYHA 1E8CA 2H4VA 2PA5A 2R0BA 2HB1A 4DGPA 1XRIA 3BLTA 5AWXA 3CM3A 2B49A 3RZ2A 2MBCA 3D1OA 1KAVA 4D3QA 2A8BA 3O4TA 5KABA 2XJAA 1YZ4A 1G1GA 1Q1MA 2B4PA 1OHEA 2ZMMA 3PS5A 3ZMQA 2F00A 2G6ZA 2OUDA 2Y67A 4BUBA 2I5XA 2GP0A 3QCLA 1C83A 1LQFA 4ZRTA 2F6FA 4YR8B 1XXPA 5IBMA 2QEPA 2VEVA 5BZZA 4JMJA 4KYRA 5K25A 1VHRA 2C7SA 2I6OA 4ERCA 2QBSA 2VTEA 1P31A 1Q6TA 4GE6A 2UUOA 2RF6A 2QBPA 2HVLA 2PSZA 4S0GA 1P15A 2QCJA 3A5JA 2E0TA 4GRZA 1SUGA 3QCZA 4GE2A
chains in the Genus database with same CATH topology
4RI4A 1C85A 1FPRA 1BZCA 1EENA 1X24A 4B04A 1YPTA 2I1YA 2BIJA 4ZN5A 2OOQA 5M43A 3U96A 2NZ6A 3V0DA 1G7FA 1KAKA 3QCEA 3QCCA 2CNFA 4RKKA 2HC1A 4H34A 3RGQA 5KA8A 4JNBA 3S4EA 4NWFA 1R6HA 3QCBA 2I6PA 2J17A 2CNHA 3D44A 3S3EA 1PTYA 3S3HA 4R0SA 4KYQA 3V0GA 1I9SA 2F70A 4Y14A 1NNYA 1M3GA 2F6ZA 2H03A 3D9CA 1PTUA 1V3AA 1U26A 2QCTA 5KA7A 3QCKA 4JMKA 3ZV2A 5KA4A 2GJTA 3QCFA 1MKPA 2CMCA 1L8GA 3RGOA 5K9WA 2F6TA 1LARA 2F6WA 1ONYA 1EEOA 3AWEA 5EHPA 2VEXA 3QCGA 5IBSA 4OHLA 1XBOA 4D3RA 3I36A 2VEWA 2CNIA 1YWFA 2CMBA 3EAXA 1YN9A 3NMEA 2NT7A 4QUNA 4QAHA 5KACA 1C88A 1PH0A 5MMZB 4KI9A 2HXPA 2FH7A 5J8RA 3ZM1A 2AHSA 2ZN7A 2BV5A 4BJOA 3D42A 3F41A 3QCDA 3EB1A 4AZ1A 3EU0A 1PTVA 1Q6MA 2VEUA 3QCMA 3BLUA 2B4UA 3O3LA 1PA9A 2QBRA 1XXVA 3ZMPA 4YAAA 1RPMA 1QXKA 1GFYA 1G1HA 1T48A 3GXGA 3F9BA 2I6IA 5KA9A 3SR9A 1PA1A 2HCMA 4NNDA 1BZHA 2B3OA 3AWGA 5LXQB 1Q6NA 2F6YA 2FJNA 3BRHA 2B07A 1C84A 2PBNA 4JBCA 3ZM3A 4WTYA 3V0JA 2F71A 3LJ8A 2I6MA 4RDDA 4HJPA 5KADA 2B4OA 5K22A 2BZLA 1GWZA 1I9TA 2P4DA 2ESBA 4TVVA 3MOZA 3N0AA 4Z6BA 3OLRA 1ZCKA 4DGXA 5GTJA 1YTSA 2YDUA 2CM2A 2J16B 4WU2A 2HNQA 3ZM0A 2QDPA 1OEOX 2B4SA 5I6VA 2BGEA 2I6JA 4R30A 2M3VA 5KA1A 1G4WR 1T49A 2J16A 3F9AA 2Y2FA 4D3PA 2PQ5A 2NTAA 1ZCLA 3MOWA 3D1QA 4PVGA 3BM8A 5K23A 4NX8A 4RI5A 3M4UA 2A3KA 1YTNA 2SHPA 4GWFA 4RHGA 1YGUA 2I3RA 4QUMA 2PI7A 4Y2EA 2NT2A 3B7OA 1OEVA 1OEUA 2HC2A 3H2XA 1FPZA 2GWOA 1QZ0A 4IKCA 3RO1A 5BX1A 4QBEA 5K24A 3O4UA 2CJZA 1PYNA 3O5XA 4OHIA 3EMUA 2JJDA 2F46A 1G7GA 5KAAA 2DXPA 1OETA 1ONZA 4I8NA 1U25A 1OEMX 4GFVA 2I4GA 2FJMA 2I4EA 3V0IA 2OC3A 2I75A 3AWFA 3F81A 1C86A 3QCJA 3EZZA 2PT0A 3QKPA 4NWGA 3I80A 3O4SA 1C87A 1WAXA 1NL9A 1Q6PA 1T4JA 2IMGA 2CNEA 1BZJA 1FQ1A 3ZM2A 4HRFA 2NV5A 2CFVA 3CWEA 3QCNA 4GE5A 5K9VA 1NZ7A 2Y96A 1J4XA 2NLKA 3SMEA 1PTTA 2I42A 1U24A 2HY3A 1Q6JA 3QKQA 2CNGA 1OHDA 1D5RA 1AAXA 3QCIA 2F6VA 1YGRA 2VEYA 5EHRA 1NO6A 1Q6SA 1ZC0A 2H4GA 1OESA 4HJQA 4H1OA 3MMJA 2H04A 2BGDA 5HDEA 4QAPA 3S3KA 4MBBA 2H4KA 2CM7A 2CM8A 4ICZA 2AZRA 2WGPA 5KA2A 1YFOA 2I3UA 1JLNA 2QDCA 1ECVA 4GRYA 3V0FA 2G59A 5KA3A 1ZZWA 1L8KA 4OHHA 1RXDA 2I4HA 2HNPA 3I7ZA 4R0TA 1LYVA 4RH5A 3F99A 4OHDA 3OMHA 2Q47A 3D1HA 3V0EA 1JF7A 1I57A 4GS0A 5BZXA 1WRMA 3S3FA 4J51A 1NWEA 5KA0A 1XM2A 4ZI4A 4BPCA 2CM3A 2QBQA 3S4OA 3QCHA 3GXHA 1A5YA 1WCHA 3A5KA 2OZ5A 1OHCA 1YTWA 4RH9A 1NWLA 4PYHA 4GFUA 2P6XA 2C46A 5BUGA 1PXHA 2CMAA 4WU3A 2H02A 1G4US 1G1FA 2Q05A 4QBWA 4WOHA 3V0HA 4OHEA 2QDMA 4NYHA 2PA5A 2H4VA 2R0BA 2HB1A 4DGPA 1XRIA 3BLTA 5AWXA 3CM3A 2B49A 3RZ2A 2MBCA 3D1OA 1KAVA 4D3QA 2A8BA 3O4TA 5KABA 1YZ4A 1G1GA 1Q1MA 2B4PA 1OHEA 2ZMMA 3PS5A 3ZMQA 2G6ZA 2OUDA 2I5XA 2GP0A 3QCLA 1C83A 1LQFA 4ZRTA 2F6FA 4YR8B 1XXPA 5IBMA 2QEPA 2VEVA 5BZZA 4JMJA 4KYRA 5K25A 1VHRA 2C7SA 2I6OA 4ERCA 2QBSA 1Q6TA 4GE6A 2RF6A 2QBPA 2HVLA 2PSZA 4S0GA 1P15A 2QCJA 3A5JA 2E0TA 4GRZA 1SUGA 4GE2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RI4 A;  1C85 A;  1FPR A;  1BZC A;  1EEN A;  1X24 A;  4B04 A;  1YPT A;  2I1Y A;  2BIJ A;  4ZN5 A;  2OOQ A;  5M43 A;  3U96 A;  2NZ6 A;  3V0D A;  1G7F A;  1KAK A;  3QCE A;  3QCC A;  2CNF A;  4RKK A;  2HC1 A;  4H34 A;  3RGQ A;  5KA8 A;  4JNB A;  3S4E A;  4NWF A;  1R6H A;  3QCB A;  2I6P A;  2J17 A;  2CNH A;  3D44 A;  3S3E A;  1PTY A;  3S3H A;  4R0S A;  4KYQ A;  3V0G A;  1I9S A;  2F70 A;  4Y14 A;  1NNY A;  1M3G A;  2F6Z A;  2H03 A;  3D9C A;  1PTU A;  1V3A A;  1U26 A;  2QCT A;  5KA7 A;  3QCK A;  4JMK A;  3ZV2 A;  5KA4 A;  2GJT A;  3QCF A;  1MKP A;  2CMC A;  1L8G A;  3RGO A;  5K9W A;  2F6T A;  1LAR A;  2F6W A;  1ONY A;  1EEO A;  3AWE A;  5EHP A;  2VEX A;  3QCG A;  5IBS A;  4OHL A;  1XBO A;  4D3R A;  3I36 A;  2VEW A;  2CNI A;  1YWF A;  2CMB A;  3EAX A;  1YN9 A;  3NME A;  2NT7 A;  4QUN A;  4QAH A;  5KAC A;  1C88 A;  1PH0 A;  5MMZ B;  4KI9 A;  2HXP A;  2FH7 A;  5J8R A;  3ZM1 A;  2AHS A;  2ZN7 A;  2BV5 A;  4BJO A;  3D42 A;  3F41 A;  3QCD A;  3EB1 A;  4AZ1 A;  3EU0 A;  1PTV A;  1Q6M A;  2VEU A;  3QCM A;  3BLU A;  2B4U A;  3O3L A;  1PA9 A;  2QBR A;  1XXV A;  3ZMP A;  4YAA A;  1RPM A;  1QXK A;  1GFY A;  1G1H A;  1T48 A;  3GXG A;  3F9B A;  2I6I A;  5KA9 A;  3SR9 A;  1PA1 A;  2HCM A;  4NND A;  1BZH A;  2B3O A;  3AWG A;  5LXQ B;  1Q6N A;  2F6Y A;  2FJN A;  3BRH A;  2B07 A;  1C84 A;  2PBN A;  4JBC A;  3ZM3 A;  4WTY A;  3V0J A;  2F71 A;  3LJ8 A;  2I6M A;  4RDD A;  4HJP A;  5KAD A;  2B4O A;  5K22 A;  2BZL A;  1GWZ A;  1I9T A;  2P4D A;  2ESB A;  4TVV A;  3MOZ A;  3N0A A;  4Z6B A;  3OLR A;  1ZCK A;  4DGX A;  5GTJ A;  1YTS A;  2YDU A;  2CM2 A;  2J16 B;  4WU2 A;  2HNQ A;  3ZM0 A;  2QDP A;  1OEO X;  2B4S A;  5I6V A;  2BGE A;  2I6J A;  4R30 A;  2M3V A;  5KA1 A;  1G4W R;  1T49 A;  2J16 A;  3F9A A;  2Y2F A;  4D3P A;  2PQ5 A;  2NTA A;  1ZCL A;  3MOW A;  3D1Q A;  4PVG A;  3BM8 A;  5K23 A;  4NX8 A;  4RI5 A;  3M4U A;  2A3K A;  1YTN A;  2SHP A;  4GWF A;  4RHG A;  1YGU A;  2I3R A;  4QUM A;  2PI7 A;  4Y2E A;  2NT2 A;  3B7O A;  1OEV A;  1OEU A;  2HC2 A;  3H2X A;  1FPZ A;  2GWO A;  1QZ0 A;  4IKC A;  3RO1 A;  5BX1 A;  4QBE A;  5K24 A;  3O4U A;  2CJZ A;  1PYN A;  3O5X A;  4OHI A;  3EMU A;  2JJD A;  2F46 A;  1G7G A;  5KAA A;  2DXP A;  1OET A;  1ONZ A;  4I8N A;  1U25 A;  1OEM X;  4GFV A;  2I4G A;  2FJM A;  2I4E A;  3V0I A;  2OC3 A;  2I75 A;  3AWF A;  3F81 A;  1C86 A;  3QCJ A;  3EZZ A;  2PT0 A;  3QKP A;  4NWG A;  3I80 A;  3O4S A;  1C87 A;  1WAX A;  1NL9 A;  1Q6P A;  1T4J A;  2IMG A;  2CNE A;  1BZJ A;  1FQ1 A;  3ZM2 A;  4HRF A;  2NV5 A;  2CFV A;  3CWE A;  3QCN A;  4GE5 A;  5K9V A;  1NZ7 A;  2Y96 A;  1J4X A;  2NLK A;  3SME A;  1PTT A;  2I42 A;  1U24 A;  2HY3 A;  1Q6J A;  3QKQ A;  2CNG A;  1OHD A;  1D5R A;  1AAX A;  3QCI A;  2F6V A;  1YGR A;  2VEY A;  5EHR A;  1NO6 A;  1Q6S A;  1ZC0 A;  2H4G A;  1OES A;  4HJQ A;  4H1O A;  3MMJ A;  2H04 A;  2BGD A;  5HDE A;  4QAP A;  3S3K A;  4MBB A;  2H4K A;  2CM7 A;  2CM8 A;  4ICZ A;  2AZR A;  2WGP A;  5KA2 A;  1YFO A;  2I3U A;  1JLN A;  2QDC A;  1ECV A;  4GRY A;  3V0F A;  2G59 A;  5KA3 A;  1ZZW A;  1L8K A;  4OHH A;  1RXD A;  2I4H A;  2HNP A;  3I7Z A;  4R0T A;  1LYV A;  4RH5 A;  3F99 A;  4OHD A;  3OMH A;  2Q47 A;  3D1H A;  3V0E A;  1JF7 A;  1I57 A;  4GS0 A;  5BZX A;  1WRM A;  3S3F A;  4J51 A;  1NWE A;  5KA0 A;  1XM2 A;  4ZI4 A;  4BPC A;  2CM3 A;  2QBQ A;  3S4O A;  3QCH A;  3GXH A;  1A5Y A;  1WCH A;  3A5K A;  2OZ5 A;  1OHC A;  1YTW A;  4RH9 A;  1NWL A;  4PYH A;  4GFU A;  2P6X A;  2C46 A;  5BUG A;  1PXH A;  2CMA A;  4WU3 A;  2H02 A;  1G4U S;  1G1F A;  2Q05 A;  4QBW A;  4WOH A;  3V0H A;  4OHE A;  2QDM A;  4NYH A;  2PA5 A;  2H4V A;  2R0B A;  2HB1 A;  4DGP A;  1XRI A;  3BLT A;  5AWX A;  3CM3 A;  2B49 A;  3RZ2 A;  2MBC A;  3D1O A;  1KAV A;  4D3Q A;  2A8B A;  3O4T A;  5KAB A;  1YZ4 A;  1G1G A;  1Q1M A;  2B4P A;  1OHE A;  2ZMM A;  3PS5 A;  3ZMQ A;  2G6Z A;  2OUD A;  2I5X A;  2GP0 A;  3QCL A;  1C83 A;  1LQF A;  4ZRT A;  2F6F A;  4YR8 B;  1XXP A;  5IBM A;  2QEP A;  2VEV A;  5BZZ A;  4JMJ A;  4KYR A;  5K25 A;  1VHR A;  2C7S A;  2I6O A;  4ERC A;  2QBS A;  1Q6T A;  4GE6 A;  2RF6 A;  2QBP A;  2HVL A;  2PSZ A;  4S0G A;  1P15 A;  2QCJ A;  3A5J A;  2E0T A;  4GRZ A;  1SUG A;  4GE2 A; 
#chains in the Genus database with same CATH topology
 4RI4 A;  1C85 A;  1FGS A;  1FPR A;  1BZC A;  1EEN A;  1X24 A;  4BUC A;  2JFG A;  4B04 A;  1YPT A;  2UUP A;  2I1Y A;  2BIJ A;  4ZN5 A;  2OOQ A;  5M43 A;  3U96 A;  2AM2 A;  2NZ6 A;  3V0D A;  1G7F A;  1KAK A;  3LK7 A;  3QCE A;  3QCC A;  2CNF A;  4RKK A;  2HC1 A;  4H34 A;  2Y1O A;  3RGQ A;  5KA8 A;  4JNB A;  3S4E A;  4NWF A;  1P3D A;  2VOR A;  1R6H A;  3QCB A;  2I6P A;  2J17 A;  2CNH A;  3D44 A;  3S3E A;  1PTY A;  3UAG A;  3S3H A;  4R0S A;  4KYQ A;  3V0G A;  1I9S A;  2F70 A;  4Y14 A;  3ZM6 A;  1NNY A;  1M3G A;  2F6Z A;  2H03 A;  3D9C A;  1PTU A;  1V3A A;  1U26 A;  2QCT A;  5KA7 A;  3QCK A;  4JMK A;  3ZV2 A;  5KA4 A;  2GJT A;  3QCF A;  1MKP A;  2CMC A;  1L8G A;  3RGO A;  5K9W A;  2F6T A;  1LAR A;  2WJP A;  2F6W A;  1ONY A;  1EEO A;  3AWE A;  2XPC A;  5EHP A;  2VEX A;  3QCG A;  5IBS A;  4OHL A;  1XBO A;  4CVM A;  4D3R A;  3I36 A;  1JBW A;  2VEW A;  2CNI A;  1YWF A;  2CMB A;  3EAX A;  1YN9 A;  3NME A;  2NT7 A;  4QUN A;  4QAH A;  5KAC A;  1C88 A;  1PH0 A;  5MMZ B;  4KI9 A;  2HXP A;  2FH7 A;  5J8R A;  3ZM1 A;  2AHS A;  2ZN7 A;  2BV5 A;  4BJO A;  3D42 A;  3F41 A;  3QCD A;  3EB1 A;  4AZ1 A;  3EU0 A;  1PTV A;  1Q6M A;  2VEU A;  3QCM A;  3BLU A;  1W7K A;  2B4U A;  3O3L A;  1PA9 A;  2JFH A;  2QBR A;  1XXV A;  3ZMP A;  4YAA A;  1RPM A;  1QXK A;  1GFY A;  2WTZ A;  2X5O A;  1G1H A;  4CVL A;  1T48 A;  3GXG A;  3F9B A;  2I6I A;  5KA9 A;  3SR9 A;  4HV4 A;  1PA1 A;  2HCM A;  4NND A;  1BZH A;  2B3O A;  3AWG A;  5LXQ B;  1Q6N A;  2F6Y A;  2FJN A;  3BRH A;  2B07 A;  1C84 A;  2PBN A;  4JBC A;  3ZM3 A;  4WTY A;  2GC6 A;  3V0J A;  2F71 A;  3LJ8 A;  2I6M A;  5A5E A;  4RDD A;  4HJP A;  5KAD A;  4QF5 A;  2B4O A;  5K22 A;  2BZL A;  1GWZ A;  1I9T A;  2P4D A;  2ESB A;  4TVV A;  1UAG A;  3MOZ A;  3N0A A;  4Z6B A;  3OLR A;  1ZCK A;  4DGX A;  5GTJ A;  1YTS A;  2YDU A;  2CM2 A;  3MVN A;  2J16 B;  4WU2 A;  2HNQ A;  3ZM0 A;  1W78 A;  1O5Z A;  2QDP A;  1OEO X;  2B4S A;  5I6V A;  3PYZ A;  2BGE A;  2I6J A;  4R30 A;  2M3V A;  5KA1 A;  1G4W R;  1T49 A;  2J16 A;  3F9A A;  2Y2F A;  4D3P A;  2PQ5 A;  2NTA A;  1ZCL A;  3MOW A;  3D1Q A;  4PVG A;  4C12 A;  3BM8 A;  5K23 A;  4NX8 A;  4CVK A;  4RI5 A;  2VOS A;  3M4U A;  2A3K A;  1YTN A;  2SHP A;  4GWF A;  4RHG A;  1YGU A;  2I3R A;  4QUM A;  2PI7 A;  1JBV A;  4Y2E A;  1GG4 A;  2NT2 A;  3B7O A;  1E0D A;  2JFF A;  1OEV A;  1OEU A;  2HC2 A;  3H2X A;  1J6U A;  1FPZ A;  2GWO A;  1QZ0 A;  4IKC A;  3RO1 A;  5BX1 A;  4QBE A;  5K24 A;  3O4U A;  2CJZ A;  1GQY A;  1PYN A;  3O5X A;  4OHI A;  3ZM5 A;  3EMU A;  2JJD A;  2F46 A;  1G7G A;  5KAA A;  2DXP A;  1EEH A;  1OET A;  1ONZ A;  4I8N A;  1U25 A;  1OEM X;  4GFV A;  2I4G A;  2GCB A;  2FJM A;  2I4E A;  3V0I A;  2OC3 A;  2I75 A;  3AWF A;  3F81 A;  1C86 A;  3QCJ A;  2VTD A;  3EZZ A;  2PT0 A;  3QKP A;  2Y68 A;  4NWG A;  3I80 A;  3O4S A;  1C87 A;  1WAX A;  2Y66 A;  1NL9 A;  1Q6P A;  1T4J A;  2IMG A;  2CNE A;  1BZJ A;  1FQ1 A;  3ZM2 A;  4HRF A;  2NV5 A;  2CFV A;  3CWE A;  3QCN A;  4GE5 A;  3NRS A;  4ZIY A;  1NZ7 A;  5K9V A;  2Y96 A;  1J4X A;  2NLK A;  3SME A;  5A5F A;  3N2A A;  1PTT A;  2AM1 A;  2I42 A;  1U24 A;  2HY3 A;  1Q6J A;  3QKQ A;  2CNG A;  1OHD A;  1D5R A;  1AAX A;  3QCI A;  2F6V A;  1YGR A;  2VEY A;  3ZL8 A;  5EHR A;  4UAG A;  1NO6 A;  1Q6S A;  1ZC0 A;  2H4G A;  1OES A;  4C13 A;  4HJQ A;  4H1O A;  3MMJ A;  2H04 A;  2BGD A;  5HDE A;  4QAP A;  3S3K A;  4MBB A;  2H4K A;  2CM7 A;  2CM8 A;  4ICZ A;  2AZR A;  2WGP A;  5KA2 A;  1YFO A;  2I3U A;  3HN7 A;  1JLN A;  2QDC A;  1ECV A;  4GRY A;  4QDI A;  3V0F A;  2G59 A;  5KA3 A;  1ZZW A;  1L8K A;  4OHH A;  1RXD A;  2I4H A;  2HNP A;  3I7Z A;  4R0T A;  1LYV A;  4RH5 A;  3F99 A;  4OHD A;  3OMH A;  2Q47 A;  3D1H A;  3V0E A;  1JF7 A;  1I57 A;  4GS0 A;  5BZX A;  1WRM A;  3S3F A;  4J51 A;  2GC5 A;  1NWE A;  5KA0 A;  1XM2 A;  4ZI4 A;  4BPC A;  2CM3 A;  2QBQ A;  3S4O A;  3QCH A;  3GXH A;  1A5Y A;  1WCH A;  3A5K A;  2OZ5 A;  2UAG A;  1OHC A;  1YTW A;  4RH9 A;  1NWL A;  4PYH A;  4GFU A;  2P6X A;  2C46 A;  5BUG A;  1PXH A;  2CMA A;  4WU3 A;  1GQQ A;  2H02 A;  2GCA A;  1G4U S;  1G1F A;  2Q05 A;  4QBW A;  4WOH A;  3V0H A;  4OHE A;  2QDM A;  4NYH A;  1E8C A;  2H4V A;  2PA5 A;  2R0B A;  2HB1 A;  4DGP A;  1XRI A;  3BLT A;  5AWX A;  3CM3 A;  2B49 A;  3RZ2 A;  2MBC A;  3D1O A;  1KAV A;  4D3Q A;  2A8B A;  3O4T A;  5KAB A;  2XJA A;  1YZ4 A;  1G1G A;  1Q1M A;  2B4P A;  1OHE A;  2ZMM A;  3PS5 A;  3ZMQ A;  2F00 A;  2G6Z A;  2OUD A;  2Y67 A;  4BUB A;  2I5X A;  2GP0 A;  3QCL A;  1C83 A;  1LQF A;  4ZRT A;  2F6F A;  4YR8 B;  1XXP A;  5IBM A;  2QEP A;  2VEV A;  5BZZ A;  4JMJ A;  4KYR A;  5K25 A;  1VHR A;  2C7S A;  2I6O A;  4ERC A;  2QBS A;  2VTE A;  1P31 A;  1Q6T A;  4GE6 A;  2UUO A;  2RF6 A;  2QBP A;  2HVL A;  2PSZ A;  4S0G A;  1P15 A;  2QCJ A;  3A5J A;  2E0T A;  4GRZ A;  1SUG A;  3QCZ A;  4GE2 A; 
#chains in the Genus database with same CATH homology
 4RI4 A;  1C85 A;  1FPR A;  1BZC A;  1EEN A;  1X24 A;  4B04 A;  1YPT A;  2I1Y A;  2BIJ A;  4ZN5 A;  2OOQ A;  5M43 A;  3U96 A;  2NZ6 A;  3V0D A;  1G7F A;  1KAK A;  3QCE A;  3QCC A;  2CNF A;  4RKK A;  2HC1 A;  4H34 A;  3RGQ A;  5KA8 A;  4JNB A;  3S4E A;  4NWF A;  1R6H A;  3QCB A;  2I6P A;  2J17 A;  2CNH A;  3D44 A;  3S3E A;  1PTY A;  3S3H A;  4R0S A;  4KYQ A;  3V0G A;  1I9S A;  2F70 A;  4Y14 A;  1NNY A;  1M3G A;  2F6Z A;  2H03 A;  3D9C A;  1PTU A;  1V3A A;  1U26 A;  2QCT A;  5KA7 A;  3QCK A;  4JMK A;  3ZV2 A;  5KA4 A;  2GJT A;  3QCF A;  1MKP A;  2CMC A;  1L8G A;  3RGO A;  5K9W A;  2F6T A;  1LAR A;  2F6W A;  1ONY A;  1EEO A;  3AWE A;  5EHP A;  2VEX A;  3QCG A;  5IBS A;  4OHL A;  1XBO A;  4D3R A;  3I36 A;  2VEW A;  2CNI A;  1YWF A;  2CMB A;  3EAX A;  1YN9 A;  3NME A;  2NT7 A;  4QUN A;  4QAH A;  5KAC A;  1C88 A;  1PH0 A;  5MMZ B;  4KI9 A;  2HXP A;  2FH7 A;  5J8R A;  3ZM1 A;  2AHS A;  2ZN7 A;  2BV5 A;  4BJO A;  3D42 A;  3F41 A;  3QCD A;  3EB1 A;  4AZ1 A;  3EU0 A;  1PTV A;  1Q6M A;  2VEU A;  3QCM A;  3BLU A;  2B4U A;  3O3L A;  1PA9 A;  2QBR A;  1XXV A;  3ZMP A;  4YAA A;  1RPM A;  1QXK A;  1GFY A;  1G1H A;  1T48 A;  3GXG A;  3F9B A;  2I6I A;  5KA9 A;  3SR9 A;  1PA1 A;  2HCM A;  4NND A;  1BZH A;  2B3O A;  3AWG A;  5LXQ B;  1Q6N A;  2F6Y A;  2FJN A;  3BRH A;  2B07 A;  1C84 A;  2PBN A;  4JBC A;  3ZM3 A;  4WTY A;  3V0J A;  2F71 A;  3LJ8 A;  2I6M A;  4RDD A;  4HJP A;  5KAD A;  2B4O A;  5K22 A;  2BZL A;  1GWZ A;  1I9T A;  2P4D A;  2ESB A;  4TVV A;  3MOZ A;  3N0A A;  4Z6B A;  3OLR A;  1ZCK A;  4DGX A;  5GTJ A;  1YTS A;  2YDU A;  2CM2 A;  2J16 B;  4WU2 A;  2HNQ A;  3ZM0 A;  2QDP A;  1OEO X;  2B4S A;  5I6V A;  2BGE A;  2I6J A;  4R30 A;  2M3V A;  5KA1 A;  1G4W R;  1T49 A;  2J16 A;  3F9A A;  2Y2F A;  4D3P A;  2PQ5 A;  2NTA A;  1ZCL A;  3MOW A;  3D1Q A;  4PVG A;  3BM8 A;  5K23 A;  4NX8 A;  4RI5 A;  3M4U A;  2A3K A;  1YTN A;  2SHP A;  4GWF A;  4RHG A;  1YGU A;  2I3R A;  4QUM A;  2PI7 A;  4Y2E A;  2NT2 A;  3B7O A;  1OEV A;  1OEU A;  2HC2 A;  3H2X A;  1FPZ A;  2GWO A;  1QZ0 A;  4IKC A;  3RO1 A;  5BX1 A;  4QBE A;  5K24 A;  3O4U A;  2CJZ A;  1PYN A;  3O5X A;  4OHI A;  3EMU A;  2JJD A;  2F46 A;  1G7G A;  5KAA A;  2DXP A;  1OET A;  1ONZ A;  4I8N A;  1U25 A;  1OEM X;  4GFV A;  2I4G A;  2FJM A;  2I4E A;  3V0I A;  2OC3 A;  2I75 A;  3AWF A;  3F81 A;  1C86 A;  3QCJ A;  3EZZ A;  2PT0 A;  3QKP A;  4NWG A;  3I80 A;  3O4S A;  1C87 A;  1WAX A;  1NL9 A;  1Q6P A;  1T4J A;  2IMG A;  2CNE A;  1BZJ A;  1FQ1 A;  3ZM2 A;  4HRF A;  2NV5 A;  2CFV A;  3CWE A;  3QCN A;  4GE5 A;  5K9V A;  1NZ7 A;  2Y96 A;  1J4X A;  2NLK A;  3SME A;  1PTT A;  2I42 A;  1U24 A;  2HY3 A;  1Q6J A;  3QKQ A;  2CNG A;  1OHD A;  1D5R A;  1AAX A;  3QCI A;  2F6V A;  1YGR A;  2VEY A;  5EHR A;  1NO6 A;  1Q6S A;  1ZC0 A;  2H4G A;  1OES A;  4HJQ A;  4H1O A;  3MMJ A;  2H04 A;  2BGD A;  5HDE A;  4QAP A;  3S3K A;  4MBB A;  2H4K A;  2CM7 A;  2CM8 A;  4ICZ A;  2AZR A;  2WGP A;  5KA2 A;  1YFO A;  2I3U A;  1JLN A;  2QDC A;  1ECV A;  4GRY A;  3V0F A;  2G59 A;  5KA3 A;  1ZZW A;  1L8K A;  4OHH A;  1RXD A;  2I4H A;  2HNP A;  3I7Z A;  4R0T A;  1LYV A;  4RH5 A;  3F99 A;  4OHD A;  3OMH A;  2Q47 A;  3D1H A;  3V0E A;  1JF7 A;  1I57 A;  4GS0 A;  5BZX A;  1WRM A;  3S3F A;  4J51 A;  1NWE A;  5KA0 A;  1XM2 A;  4ZI4 A;  4BPC A;  2CM3 A;  2QBQ A;  3S4O A;  3QCH A;  3GXH A;  1A5Y A;  1WCH A;  3A5K A;  2OZ5 A;  1OHC A;  1YTW A;  4RH9 A;  1NWL A;  4PYH A;  4GFU A;  2P6X A;  2C46 A;  5BUG A;  1PXH A;  2CMA A;  4WU3 A;  2H02 A;  1G4U S;  1G1F A;  2Q05 A;  4QBW A;  4WOH A;  3V0H A;  4OHE A;  2QDM A;  4NYH A;  2PA5 A;  2H4V A;  2R0B A;  2HB1 A;  4DGP A;  1XRI A;  3BLT A;  5AWX A;  3CM3 A;  2B49 A;  3RZ2 A;  2MBC A;  3D1O A;  1KAV A;  4D3Q A;  2A8B A;  3O4T A;  5KAB A;  1YZ4 A;  1G1G A;  1Q1M A;  2B4P A;  1OHE A;  2ZMM A;  3PS5 A;  3ZMQ A;  2G6Z A;  2OUD A;  2I5X A;  2GP0 A;  3QCL A;  1C83 A;  1LQF A;  4ZRT A;  2F6F A;  4YR8 B;  1XXP A;  5IBM A;  2QEP A;  2VEV A;  5BZZ A;  4JMJ A;  4KYR A;  5K25 A;  1VHR A;  2C7S A;  2I6O A;  4ERC A;  2QBS A;  1Q6T A;  4GE6 A;  2RF6 A;  2QBP A;  2HVL A;  2PSZ A;  4S0G A;  1P15 A;  2QCJ A;  3A5J A;  2E0T A;  4GRZ A;  1SUG A;  4GE2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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