2I4EA

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
292
structure length
281
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGERLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase beta
total genus 102
structure length 281
sequence length 292
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2i4eA00
4ICZA 1Q6MA 2I6OA 3V0EA 3O4TA 4RHGA 4D3PA 2HCMA 3RGQA 1RXDA 3RO1A 2VEYA 3H2XA 3O5XA 3S4EA 1OHCA 3GXGA 4ZRTA 1MKPA 1PTUA 2B3OA 2H03A 4QAHA 5AWXA 1OEMX 1GFYA 4R30A 4GRYA 1OESA 2B49A 4NYHA 4DGPA 1J4XA 3B7OA 3D1HA 2C46A 2FJNA 2B4SA 3QCFA 3N0AA 2HC2A 2VEXA 1ZCKA 4Y2EA 5BZXA 2AHSA 4BJOA 4R0TA 3F81A 2ESBA 4PYHA 2I6IA 2F6FA 3QCBA 2VEUA 3AWEA 3ZM0A 4ZI4A 1NWEA 1FPRA 2QDPA 3PS5A 3F99A 5K24A 1Q6NA 5KA4A 4QUMA 2B4PA 2OC3A 3CM3A 1U26A 5KA3A 2QBPA 3A5KA 5K23A 3D9CA 1L8GA 5KA9A 1PTYA 1Q6TA 2Y96A 2YDUA 4DGXA 4MBBA 1ZZWA 5M43A 1G1HA 4QUNA 2QBRA 5BX1A 1NL9A 5KAAA 3BRHA 1YTWA 3AWFA 3QCHA 4KI9A 4R0SA 1XBOA 1U25A 2F6ZA 4RI5A 3V0GA 3QCJA 2CMCA 2B07A 2QDCA 2WGPA 2B4OA 5BUGA 3ZM3A 1YTSA 1AAXA 1YWFA 4NNDA 2VEWA 1EENA 2NZ6A 2I4EA 3MMJA 4GE2A 1WRMA 4HRFA 3SR9A 1T49A 4GE5A 1C86A 1ONZA 4WU3A 4OHHA 2GJTA 2A3KA 1NWLA 2NTAA 3QCLA 1PA1A 2E0TA 2HNQA 4WTYA 3MOWA 4D3QA 5MMZB 4H1OA 2CNFA 2CNIA 3ZMPA 1C83A 4JMJA 3AWGA 5K25A 1BZJA 1SUGA 3QKPA 2SHPA 2BGDA 3V0IA 3MOZA 1QXKA 1PH0A 2NT7A 4GFUA 1Q6PA 2Y2FA 3OLRA 3V0DA 2HB1A 3D42A 2ZN7A 2J17A 4KYQA 2GP0A 1EEOA 2F71A 1OEVA 2Q47A 2GWOA 3D1OA 3RGOA 2I5XA 1YPTA 4KYRA 3RZ2A 2HNPA 2CM8A 3QCMA 4I8NA 1C88A 2DXPA 1G1FA 3BM8A 2I3UA 1YZ4A 1G1GA 3F41A 1NNYA 4GE6A 2F70A 2QBSA 1ZC0A 2F6WA 3EAXA 4TVVA 2I4GA 2G6ZA 1JF7A 2CNGA 1YFOA 3QCIA 2PQ5A 4OHDA 2OUDA 4HJPA 1ONYA 3D44A 2CFVA 3OMHA 1PA9A 3SMEA 1YN9A 2NT2A 1PTTA 1G4WR 2H4GA 1OHDA 1BZCA 1BZHA 1ZCLA 2PSZA 4IKCA 4QBWA 1I57A 2B4UA 1OETA 1A5YA 1YGUA 2P6XA 2CJZA 5KA7A 3V0HA 5K9VA 2BZLA 3O4UA 2CNHA 3EMUA 4Y14A 2PI7A 1KAKA 5KA1A 4GRZA 3NMEA 2QBQA 1NO6A 1QZ0A 4JMKA 4AZ1A 2QCJA 1G4US 3I80A 3S3KA 1Q6SA 3ZM1A 5LXQB 2J16B 3QKQA 4HJQA 1YGRA 5BZZA 3S3EA 2NV5A 1JLNA 2I75A 1PTVA 5KA0A 1OHEA 4NWFA 2F6TA 2M3VA 2ZMMA 4GWFA 3EU0A 3BLUA 1WCHA 1C84A 4J51A 2CM3A 2HY3A 1VHRA 4YR8B 2CNEA 2FJMA 5EHRA 1I9TA 1GWZA 5KA2A 1WAXA 3QCGA 1OEOX 3GXHA 3QCDA 4ERCA 2BGEA 1G7FA 5K9WA 2H02A 4WU2A 4RKKA 1FQ1A 2C7SA 2F6YA 2P4DA 4RI4A 4BPCA 1C85A 1D5RA 4GFVA 2I6JA 3S3FA 2JJDA 3I7ZA 3V0JA 1PXHA 1T48A 5I6VA 1Q1MA 2F6VA 2R0BA 1LYVA 4RH5A 2MBCA 5HDEA 4ZN5A 5KADA 2G59A 3M4UA 3QCNA 1C87A 2PT0A 2CM2A 4OHLA 1M3GA 4PVGA 3F9BA 1KAVA 1XXVA 2AZRA 2I6PA 2QCTA 2J16A 2BIJA 3LJ8A 4NX8A 3O3LA 2I42A 3QCCA 4JNBA 3QCKA 4QBEA 2H4VA 2Q05A 4OHIA 2I3RA 1L8KA 4OHEA 2RF6A 1LQFA 3I36A 4RH9A 3ZV2A 3O4SA 1ECVA 3U96A 1OEUA 1G7GA 2PBNA 2IMGA 4NWGA 3EB1A 2CMAA 1X24A 2I1YA 3D1QA 2F46A 2HVLA 3ZMQA 5K22A 3ZM2A 2CM7A 4D3RA 4YAAA 5KABA 5KA8A 2H4KA 5KACA 1XXPA 4QAPA 2HXPA 2VEVA 1LARA 2I4HA 5EHPA 3A5JA 5GTJA 2QDMA 1I9SA 2CMBA 3S4OA 4Z6BA 1NZ7A 1R6HA 1U24A 2I6MA 1Q6JA 1T4JA 2PA5A 2H04A 4H34A 2OZ5A 3F9AA 4GS0A 4S0GA 4RDDA 1V3AA 1YTNA 1RPMA 5J8RA 2OOQA 3CWEA 2NLKA 1PYNA 2HC1A 5IBMA 4WOHA 1XRIA 5IBSA 2QEPA 1FPZA 3V0FA 1XM2A 2BV5A 2FH7A 3EZZA 3BLTA 4JBCA 3QCEA 3S3HA 4B04A 1P15A 2A8BA
chains in the Genus database with same CATH superfamily
4ICZA 1Q6MA 2I6OA 3V0EA 3O4TA 4RHGA 3QCZA 1P3DA 2F00A 4D3PA 2HCMA 3RGQA 1RXDA 2XPCA 3RO1A 4C13A 2VEYA 3H2XA 3O5XA 3S4EA 1OHCA 3GXGA 4ZRTA 1MKPA 1PTUA 2B3OA 2H03A 4QAHA 5AWXA 1OEMX 1GFYA 4CVMA 4R30A 4GRYA 1OESA 2B49A 4NYHA 4DGPA 1J4XA 3B7OA 3D1HA 2C46A 2FJNA 2B4SA 2JFHA 3QCFA 3N0AA 2HC2A 4ZIYA 1E8CA 1ZCKA 2VEXA 4Y2EA 5BZXA 2AHSA 4BJOA 4R0TA 3F81A 2ESBA 4PYHA 2I6IA 2F6FA 3QCBA 2VEUA 2Y67A 3AWEA 3ZM0A 2UUPA 1NWEA 4ZI4A 1FPRA 1GQYA 2QDPA 3PS5A 3F99A 5K24A 1Q6NA 5KA4A 1JBWA 2AM1A 1W7KA 3CM3A 2B4PA 2OC3A 4QUMA 1U26A 5KA3A 2QBPA 3A5KA 5K23A 3MVNA 3D9CA 1L8GA 5KA9A 1PTYA 1Q6TA 2Y96A 2YDUA 4DGXA 4MBBA 1ZZWA 5M43A 1G1HA 4QUNA 2QBRA 5BX1A 1NL9A 5KAAA 2Y66A 3BRHA 1YTWA 3AWFA 3QCHA 4KI9A 4R0SA 1XBOA 1U25A 2F6ZA 2WJPA 4RI5A 3V0GA 3QCJA 2XJAA 2CMCA 2B07A 2QDCA 2WGPA 2B4OA 5BUGA 3ZM3A 1YTSA 1AAXA 1YWFA 4NNDA 2VEWA 1J6UA 1EENA 2NZ6A 2I4EA 3MMJA 4GE2A 1E0DA 1WRMA 4HRFA 4C12A 3SR9A 1T49A 4QDIA 4GE5A 1C86A 1ONZA 4WU3A 4OHHA 2JFGA 2GJTA 2A3KA 1NWLA 2NTAA 3QCLA 1PA1A 2E0TA 2HNQA 2VTDA 4WTYA 3MOWA 4D3QA 5MMZB 2X5OA 4H1OA 2CNFA 2CNIA 3ZMPA 1C83A 4JMJA 3AWGA 5K25A 1BZJA 1SUGA 3QKPA 2SHPA 2BGDA 3V0IA 3MOZA 1PH0A 1QXKA 2NT7A 4GFUA 1Q6PA 2Y2FA 3OLRA 3V0DA 2WTZA 1GQQA 2HB1A 3D42A 2ZN7A 2J17A 4KYQA 2GP0A 1EEOA 2F71A 1OEVA 2Q47A 2GWOA 2UAGA 3D1OA 3RGOA 2I5XA 1YPTA 1W78A 3HN7A 4KYRA 3RZ2A 1O5ZA 4UAGA 2HNPA 2AM2A 2CM8A 3QCMA 2VTEA 4I8NA 1C88A 2DXPA 1G1FA 3BM8A 2I3UA 1YZ4A 1G1GA 3F41A 1GG4A 1NNYA 4GE6A 2F70A 2QBSA 1ZC0A 2F6WA 3EAXA 4TVVA 2I4GA 2G6ZA 1JF7A 3ZM5A 2CNGA 1YFOA 3QCIA 2PQ5A 4OHDA 2OUDA 2Y68A 4HJPA 1ONYA 2JFFA 4HV4A 3D44A 2CFVA 3OMHA 3NRSA 1PA9A 3SMEA 1YN9A 2NT2A 1PTTA 1G4WR 3ZM6A 2H4GA 1OHDA 1BZCA 1BZHA 1ZCLA 2PSZA 4IKCA 2GCBA 3PYZA 4QBWA 1I57A 2B4UA 1OETA 1A5YA 1YGUA 2P6XA 2CJZA 3N2AA 5KA7A 3V0HA 5K9VA 2BZLA 1P31A 3O4UA 2CNHA 3EMUA 4Y14A 2PI7A 1KAKA 5KA1A 4GRZA 3NMEA 2Y1OA 2VOSA 2QBQA 1NO6A 1QZ0A 4JMKA 4AZ1A 2QCJA 1G4US 3I80A 3S3KA 1Q6SA 3ZM1A 5LXQB 2J16B 3QKQA 4HJQA 1YGRA 5BZZA 3S3EA 2NV5A 1JLNA 2I75A 1PTVA 5KA0A 1OHEA 4NWFA 2F6TA 2M3VA 2ZMMA 4GWFA 3EU0A 3BLUA 4CVKA 1WCHA 1C84A 4J51A 2CM3A 5A5EA 2HY3A 4QF5A 1VHRA 4YR8B 2CNEA 2FJMA 5EHRA 1I9TA 1GWZA 5KA2A 1WAXA 3QCGA 1OEOX 3GXHA 3QCDA 4ERCA 2BGEA 2GC5A 1G7FA 5K9WA 2H02A 4WU2A 4RKKA 1FQ1A 2C7SA 2F6YA 2P4DA 4RI4A 4BPCA 1C85A 1D5RA 4GFVA 2I6JA 3S3FA 2JJDA 3I7ZA 3V0JA 1PXHA 1T48A 5I6VA 1JBVA 1Q1MA 2F6VA 2R0BA 1FGSA 1LYVA 4RH5A 2MBCA 5HDEA 4ZN5A 5KADA 2G59A 3UAGA 3M4UA 3QCNA 1C87A 2PT0A 2CM2A 4OHLA 1M3GA 4PVGA 3F9BA 1KAVA 1XXVA 2AZRA 2I6PA 5A5FA 2QCTA 2J16A 2BIJA 3LJ8A 4NX8A 3O3LA 2I42A 3QCCA 4JNBA 3QCKA 4QBEA 2H4VA 2GC6A 1UAGA 2Q05A 2UUOA 4OHIA 2I3RA 1L8KA 4OHEA 2RF6A 1LQFA 3I36A 4RH9A 3ZV2A 3O4SA 1ECVA 3U96A 1OEUA 1G7GA 2PBNA 2IMGA 4NWGA 3EB1A 2CMAA 4CVLA 1X24A 2I1YA 3D1QA 2F46A 3ZL8A 2HVLA 3ZMQA 5K22A 3ZM2A 4BUBA 2CM7A 4D3RA 4YAAA 5KABA 5KA8A 2H4KA 5KACA 1XXPA 4QAPA 2HXPA 2VEVA 1LARA 2I4HA 5EHPA 3A5JA 5GTJA 2QDMA 1I9SA 2CMBA 3S4OA 2GCAA 4Z6BA 1NZ7A 1R6HA 1U24A 2I6MA 1Q6JA 1T4JA 2PA5A 2H04A 4H34A 4BUCA 2OZ5A 3F9AA 4GS0A 4S0GA 4RDDA 1V3AA 1YTNA 1RPMA 3LK7A 5J8RA 2OOQA 3CWEA 2NLKA 1PYNA 2HC1A 5IBMA 4WOHA 1XRIA 5IBSA 2QEPA 1FPZA 3V0FA 1XM2A 2BV5A 2VORA 2FH7A 3EZZA 3BLTA 4JBCA 3QCEA 3S3HA 4B04A 1P15A 1EEHA 2A8BA
chains in the Genus database with same CATH topology
4ICZA 1Q6MA 2I6OA 3V0EA 3O4TA 4RHGA 4D3PA 2HCMA 3RGQA 1RXDA 3RO1A 2VEYA 3H2XA 3O5XA 3S4EA 1OHCA 3GXGA 4ZRTA 1MKPA 1PTUA 2B3OA 2H03A 4QAHA 5AWXA 1OEMX 1GFYA 4R30A 4GRYA 1OESA 2B49A 4NYHA 4DGPA 1J4XA 3B7OA 3D1HA 2C46A 2FJNA 2B4SA 3QCFA 3N0AA 2HC2A 2VEXA 1ZCKA 4Y2EA 5BZXA 2AHSA 4BJOA 4R0TA 3F81A 2ESBA 4PYHA 2I6IA 2F6FA 3QCBA 2VEUA 3AWEA 3ZM0A 4ZI4A 1NWEA 1FPRA 2QDPA 3PS5A 3F99A 5K24A 1Q6NA 5KA4A 4QUMA 2B4PA 2OC3A 3CM3A 1U26A 5KA3A 2QBPA 3A5KA 5K23A 3D9CA 1L8GA 5KA9A 1PTYA 1Q6TA 2Y96A 2YDUA 4DGXA 4MBBA 1ZZWA 5M43A 1G1HA 4QUNA 2QBRA 5BX1A 1NL9A 5KAAA 3BRHA 1YTWA 3AWFA 3QCHA 4KI9A 4R0SA 1XBOA 1U25A 2F6ZA 4RI5A 3V0GA 3QCJA 2CMCA 2B07A 2QDCA 2WGPA 2B4OA 5BUGA 3ZM3A 1YTSA 1AAXA 1YWFA 4NNDA 2VEWA 1EENA 2NZ6A 2I4EA 3MMJA 4GE2A 1WRMA 4HRFA 3SR9A 1T49A 4GE5A 1C86A 1ONZA 4WU3A 4OHHA 2GJTA 2A3KA 1NWLA 2NTAA 3QCLA 1PA1A 2E0TA 2HNQA 4WTYA 3MOWA 4D3QA 5MMZB 4H1OA 2CNFA 2CNIA 3ZMPA 1C83A 4JMJA 3AWGA 5K25A 1BZJA 1SUGA 3QKPA 2SHPA 2BGDA 3V0IA 3MOZA 1QXKA 1PH0A 2NT7A 4GFUA 1Q6PA 2Y2FA 3OLRA 3V0DA 2HB1A 3D42A 2ZN7A 2J17A 4KYQA 2GP0A 1EEOA 2F71A 1OEVA 2Q47A 2GWOA 3D1OA 3RGOA 2I5XA 1YPTA 4KYRA 3RZ2A 2HNPA 2CM8A 3QCMA 4I8NA 1C88A 2DXPA 1G1FA 3BM8A 2I3UA 1YZ4A 1G1GA 3F41A 1NNYA 4GE6A 2F70A 2QBSA 1ZC0A 2F6WA 3EAXA 4TVVA 2I4GA 2G6ZA 1JF7A 2CNGA 1YFOA 3QCIA 2PQ5A 4OHDA 2OUDA 4HJPA 1ONYA 3D44A 2CFVA 3OMHA 1PA9A 3SMEA 1YN9A 2NT2A 1PTTA 1G4WR 2H4GA 1OHDA 1BZCA 1BZHA 1ZCLA 2PSZA 4IKCA 4QBWA 1I57A 2B4UA 1OETA 1A5YA 1YGUA 2P6XA 2CJZA 5KA7A 3V0HA 5K9VA 2BZLA 3O4UA 2CNHA 3EMUA 4Y14A 2PI7A 1KAKA 5KA1A 4GRZA 3NMEA 2QBQA 1NO6A 1QZ0A 4JMKA 4AZ1A 2QCJA 1G4US 3I80A 3S3KA 1Q6SA 3ZM1A 5LXQB 2J16B 3QKQA 4HJQA 1YGRA 5BZZA 3S3EA 2NV5A 1JLNA 2I75A 1PTVA 5KA0A 1OHEA 4NWFA 2F6TA 2M3VA 2ZMMA 4GWFA 3EU0A 3BLUA 1WCHA 1C84A 4J51A 2CM3A 2HY3A 1VHRA 4YR8B 2CNEA 2FJMA 5EHRA 1I9TA 1GWZA 5KA2A 1WAXA 3QCGA 1OEOX 3GXHA 3QCDA 4ERCA 2BGEA 1G7FA 5K9WA 2H02A 4WU2A 4RKKA 1FQ1A 2C7SA 2F6YA 2P4DA 4RI4A 4BPCA 1C85A 1D5RA 4GFVA 2I6JA 3S3FA 2JJDA 3I7ZA 3V0JA 1PXHA 1T48A 5I6VA 1Q1MA 2F6VA 2R0BA 1LYVA 4RH5A 2MBCA 5HDEA 4ZN5A 5KADA 2G59A 3M4UA 3QCNA 1C87A 2PT0A 2CM2A 4OHLA 1M3GA 4PVGA 3F9BA 1KAVA 1XXVA 2AZRA 2I6PA 2QCTA 2J16A 2BIJA 3LJ8A 4NX8A 3O3LA 2I42A 3QCCA 4JNBA 3QCKA 4QBEA 2H4VA 2Q05A 4OHIA 2I3RA 1L8KA 4OHEA 2RF6A 1LQFA 3I36A 4RH9A 3ZV2A 3O4SA 1ECVA 3U96A 1OEUA 1G7GA 2PBNA 2IMGA 4NWGA 3EB1A 2CMAA 1X24A 2I1YA 3D1QA 2F46A 2HVLA 3ZMQA 5K22A 3ZM2A 2CM7A 4D3RA 4YAAA 5KABA 5KA8A 2H4KA 5KACA 1XXPA 4QAPA 2HXPA 2VEVA 1LARA 2I4HA 5EHPA 3A5JA 5GTJA 2QDMA 1I9SA 2CMBA 3S4OA 4Z6BA 1NZ7A 1R6HA 1U24A 2I6MA 1Q6JA 1T4JA 2PA5A 2H04A 4H34A 2OZ5A 3F9AA 4GS0A 4S0GA 4RDDA 1V3AA 1YTNA 1RPMA 5J8RA 2OOQA 3CWEA 2NLKA 1PYNA 2HC1A 5IBMA 4WOHA 1XRIA 5IBSA 2QEPA 1FPZA 3V0FA 1XM2A 2BV5A 2FH7A 3EZZA 3BLTA 4JBCA 3QCEA 3S3HA 4B04A 1P15A 2A8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ICZ A;  1Q6M A;  2I6O A;  3V0E A;  3O4T A;  4RHG A;  4D3P A;  2HCM A;  3RGQ A;  1RXD A;  3RO1 A;  2VEY A;  3H2X A;  3O5X A;  3S4E A;  1OHC A;  3GXG A;  4ZRT A;  1MKP A;  1PTU A;  2B3O A;  2H03 A;  4QAH A;  5AWX A;  1OEM X;  1GFY A;  4R30 A;  4GRY A;  1OES A;  2B49 A;  4NYH A;  4DGP A;  1J4X A;  3B7O A;  3D1H A;  2C46 A;  2FJN A;  2B4S A;  3QCF A;  3N0A A;  2HC2 A;  2VEX A;  1ZCK A;  4Y2E A;  5BZX A;  2AHS A;  4BJO A;  4R0T A;  3F81 A;  2ESB A;  4PYH A;  2I6I A;  2F6F A;  3QCB A;  2VEU A;  3AWE A;  3ZM0 A;  4ZI4 A;  1NWE A;  1FPR A;  2QDP A;  3PS5 A;  3F99 A;  5K24 A;  1Q6N A;  5KA4 A;  4QUM A;  2B4P A;  2OC3 A;  3CM3 A;  1U26 A;  5KA3 A;  2QBP A;  3A5K A;  5K23 A;  3D9C A;  1L8G A;  5KA9 A;  1PTY A;  1Q6T A;  2Y96 A;  2YDU A;  4DGX A;  4MBB A;  1ZZW A;  5M43 A;  1G1H A;  4QUN A;  2QBR A;  5BX1 A;  1NL9 A;  5KAA A;  3BRH A;  1YTW A;  3AWF A;  3QCH A;  4KI9 A;  4R0S A;  1XBO A;  1U25 A;  2F6Z A;  4RI5 A;  3V0G A;  3QCJ A;  2CMC A;  2B07 A;  2QDC A;  2WGP A;  2B4O A;  5BUG A;  3ZM3 A;  1YTS A;  1AAX A;  1YWF A;  4NND A;  2VEW A;  1EEN A;  2NZ6 A;  2I4E A;  3MMJ A;  4GE2 A;  1WRM A;  4HRF A;  3SR9 A;  1T49 A;  4GE5 A;  1C86 A;  1ONZ A;  4WU3 A;  4OHH A;  2GJT A;  2A3K A;  1NWL A;  2NTA A;  3QCL A;  1PA1 A;  2E0T A;  2HNQ A;  4WTY A;  3MOW A;  4D3Q A;  5MMZ B;  4H1O A;  2CNF A;  2CNI A;  3ZMP A;  1C83 A;  4JMJ A;  3AWG A;  5K25 A;  1BZJ A;  1SUG A;  3QKP A;  2SHP A;  2BGD A;  3V0I A;  3MOZ A;  1QXK A;  1PH0 A;  2NT7 A;  4GFU A;  1Q6P A;  2Y2F A;  3OLR A;  3V0D A;  2HB1 A;  3D42 A;  2ZN7 A;  2J17 A;  4KYQ A;  2GP0 A;  1EEO A;  2F71 A;  1OEV A;  2Q47 A;  2GWO A;  3D1O A;  3RGO A;  2I5X A;  1YPT A;  4KYR A;  3RZ2 A;  2HNP A;  2CM8 A;  3QCM A;  4I8N A;  1C88 A;  2DXP A;  1G1F A;  3BM8 A;  2I3U A;  1YZ4 A;  1G1G A;  3F41 A;  1NNY A;  4GE6 A;  2F70 A;  2QBS A;  1ZC0 A;  2F6W A;  3EAX A;  4TVV A;  2I4G A;  2G6Z A;  1JF7 A;  2CNG A;  1YFO A;  3QCI A;  2PQ5 A;  4OHD A;  2OUD A;  4HJP A;  1ONY A;  3D44 A;  2CFV A;  3OMH A;  1PA9 A;  3SME A;  1YN9 A;  2NT2 A;  1PTT A;  1G4W R;  2H4G A;  1OHD A;  1BZC A;  1BZH A;  1ZCL A;  2PSZ A;  4IKC A;  4QBW A;  1I57 A;  2B4U A;  1OET A;  1A5Y A;  1YGU A;  2P6X A;  2CJZ A;  5KA7 A;  3V0H A;  5K9V A;  2BZL A;  3O4U A;  2CNH A;  3EMU A;  4Y14 A;  2PI7 A;  1KAK A;  5KA1 A;  4GRZ A;  3NME A;  2QBQ A;  1NO6 A;  1QZ0 A;  4JMK A;  4AZ1 A;  2QCJ A;  1G4U S;  3I80 A;  3S3K A;  1Q6S A;  3ZM1 A;  5LXQ B;  2J16 B;  3QKQ A;  4HJQ A;  1YGR A;  5BZZ A;  3S3E A;  2NV5 A;  1JLN A;  2I75 A;  1PTV A;  5KA0 A;  1OHE A;  4NWF A;  2F6T A;  2M3V A;  2ZMM A;  4GWF A;  3EU0 A;  3BLU A;  1WCH A;  1C84 A;  4J51 A;  2CM3 A;  2HY3 A;  1VHR A;  4YR8 B;  2CNE A;  2FJM A;  5EHR A;  1I9T A;  1GWZ A;  5KA2 A;  1WAX A;  3QCG A;  1OEO X;  3GXH A;  3QCD A;  4ERC A;  2BGE A;  1G7F A;  5K9W A;  2H02 A;  4WU2 A;  4RKK A;  1FQ1 A;  2C7S A;  2F6Y A;  2P4D A;  4RI4 A;  4BPC A;  1C85 A;  1D5R A;  4GFV A;  2I6J A;  3S3F A;  2JJD A;  3I7Z A;  3V0J A;  1PXH A;  1T48 A;  5I6V A;  1Q1M A;  2F6V A;  2R0B A;  1LYV A;  4RH5 A;  2MBC A;  5HDE A;  4ZN5 A;  5KAD A;  2G59 A;  3M4U A;  3QCN A;  1C87 A;  2PT0 A;  2CM2 A;  4OHL A;  1M3G A;  4PVG A;  3F9B A;  1KAV A;  1XXV A;  2AZR A;  2I6P A;  2QCT A;  2J16 A;  2BIJ A;  3LJ8 A;  4NX8 A;  3O3L A;  2I42 A;  3QCC A;  4JNB A;  3QCK A;  4QBE A;  2H4V A;  2Q05 A;  4OHI A;  2I3R A;  1L8K A;  4OHE A;  2RF6 A;  1LQF A;  3I36 A;  4RH9 A;  3ZV2 A;  3O4S A;  1ECV A;  3U96 A;  1OEU A;  1G7G A;  2PBN A;  2IMG A;  4NWG A;  3EB1 A;  2CMA A;  1X24 A;  2I1Y A;  3D1Q A;  2F46 A;  2HVL A;  3ZMQ A;  5K22 A;  3ZM2 A;  2CM7 A;  4D3R A;  4YAA A;  5KAB A;  5KA8 A;  2H4K A;  5KAC A;  1XXP A;  4QAP A;  2HXP A;  2VEV A;  1LAR A;  2I4H A;  5EHP A;  3A5J A;  5GTJ A;  2QDM A;  1I9S A;  2CMB A;  3S4O A;  4Z6B A;  1NZ7 A;  1R6H A;  1U24 A;  2I6M A;  1Q6J A;  1T4J A;  2PA5 A;  2H04 A;  4H34 A;  2OZ5 A;  3F9A A;  4GS0 A;  4S0G A;  4RDD A;  1V3A A;  1YTN A;  1RPM A;  5J8R A;  2OOQ A;  3CWE A;  2NLK A;  1PYN A;  2HC1 A;  5IBM A;  4WOH A;  1XRI A;  5IBS A;  2QEP A;  1FPZ A;  3V0F A;  1XM2 A;  2BV5 A;  2FH7 A;  3EZZ A;  3BLT A;  4JBC A;  3QCE A;  3S3H A;  4B04 A;  1P15 A;  2A8B A; 
#chains in the Genus database with same CATH topology
 4ICZ A;  1Q6M A;  2I6O A;  3V0E A;  3O4T A;  4RHG A;  3QCZ A;  1P3D A;  2F00 A;  4D3P A;  2HCM A;  3RGQ A;  1RXD A;  2XPC A;  3RO1 A;  4C13 A;  2VEY A;  3H2X A;  3O5X A;  3S4E A;  1OHC A;  3GXG A;  4ZRT A;  1MKP A;  1PTU A;  2B3O A;  2H03 A;  4QAH A;  5AWX A;  1OEM X;  1GFY A;  4CVM A;  4R30 A;  4GRY A;  1OES A;  2B49 A;  4NYH A;  4DGP A;  1J4X A;  3B7O A;  3D1H A;  2C46 A;  2FJN A;  2B4S A;  2JFH A;  3QCF A;  3N0A A;  2HC2 A;  4ZIY A;  1E8C A;  1ZCK A;  2VEX A;  4Y2E A;  5BZX A;  2AHS A;  4BJO A;  4R0T A;  3F81 A;  2ESB A;  4PYH A;  2I6I A;  2F6F A;  3QCB A;  2VEU A;  2Y67 A;  3AWE A;  3ZM0 A;  2UUP A;  1NWE A;  4ZI4 A;  1FPR A;  1GQY A;  2QDP A;  3PS5 A;  3F99 A;  5K24 A;  1Q6N A;  5KA4 A;  1JBW A;  2AM1 A;  1W7K A;  3CM3 A;  2B4P A;  2OC3 A;  4QUM A;  1U26 A;  5KA3 A;  2QBP A;  3A5K A;  5K23 A;  3MVN A;  3D9C A;  1L8G A;  5KA9 A;  1PTY A;  1Q6T A;  2Y96 A;  2YDU A;  4DGX A;  4MBB A;  1ZZW A;  5M43 A;  1G1H A;  4QUN A;  2QBR A;  5BX1 A;  1NL9 A;  5KAA A;  2Y66 A;  3BRH A;  1YTW A;  3AWF A;  3QCH A;  4KI9 A;  4R0S A;  1XBO A;  1U25 A;  2F6Z A;  2WJP A;  4RI5 A;  3V0G A;  3QCJ A;  2XJA A;  2CMC A;  2B07 A;  2QDC A;  2WGP A;  2B4O A;  5BUG A;  3ZM3 A;  1YTS A;  1AAX A;  1YWF A;  4NND A;  2VEW A;  1J6U A;  1EEN A;  2NZ6 A;  2I4E A;  3MMJ A;  4GE2 A;  1E0D A;  1WRM A;  4HRF A;  4C12 A;  3SR9 A;  1T49 A;  4QDI A;  4GE5 A;  1C86 A;  1ONZ A;  4WU3 A;  4OHH A;  2JFG A;  2GJT A;  2A3K A;  1NWL A;  2NTA A;  3QCL A;  1PA1 A;  2E0T A;  2HNQ A;  2VTD A;  4WTY A;  3MOW A;  4D3Q A;  5MMZ B;  2X5O A;  4H1O A;  2CNF A;  2CNI A;  3ZMP A;  1C83 A;  4JMJ A;  3AWG A;  5K25 A;  1BZJ A;  1SUG A;  3QKP A;  2SHP A;  2BGD A;  3V0I A;  3MOZ A;  1PH0 A;  1QXK A;  2NT7 A;  4GFU A;  1Q6P A;  2Y2F A;  3OLR A;  3V0D A;  2WTZ A;  1GQQ A;  2HB1 A;  3D42 A;  2ZN7 A;  2J17 A;  4KYQ A;  2GP0 A;  1EEO A;  2F71 A;  1OEV A;  2Q47 A;  2GWO A;  2UAG A;  3D1O A;  3RGO A;  2I5X A;  1YPT A;  1W78 A;  3HN7 A;  4KYR A;  3RZ2 A;  1O5Z A;  4UAG A;  2HNP A;  2AM2 A;  2CM8 A;  3QCM A;  2VTE A;  4I8N A;  1C88 A;  2DXP A;  1G1F A;  3BM8 A;  2I3U A;  1YZ4 A;  1G1G A;  3F41 A;  1GG4 A;  1NNY A;  4GE6 A;  2F70 A;  2QBS A;  1ZC0 A;  2F6W A;  3EAX A;  4TVV A;  2I4G A;  2G6Z A;  1JF7 A;  3ZM5 A;  2CNG A;  1YFO A;  3QCI A;  2PQ5 A;  4OHD A;  2OUD A;  2Y68 A;  4HJP A;  1ONY A;  2JFF A;  4HV4 A;  3D44 A;  2CFV A;  3OMH A;  3NRS A;  1PA9 A;  3SME A;  1YN9 A;  2NT2 A;  1PTT A;  1G4W R;  3ZM6 A;  2H4G A;  1OHD A;  1BZC A;  1BZH A;  1ZCL A;  2PSZ A;  4IKC A;  2GCB A;  3PYZ A;  4QBW A;  1I57 A;  2B4U A;  1OET A;  1A5Y A;  1YGU A;  2P6X A;  2CJZ A;  3N2A A;  5KA7 A;  3V0H A;  5K9V A;  2BZL A;  1P31 A;  3O4U A;  2CNH A;  3EMU A;  4Y14 A;  2PI7 A;  1KAK A;  5KA1 A;  4GRZ A;  3NME A;  2Y1O A;  2VOS A;  2QBQ A;  1NO6 A;  1QZ0 A;  4JMK A;  4AZ1 A;  2QCJ A;  1G4U S;  3I80 A;  3S3K A;  1Q6S A;  3ZM1 A;  5LXQ B;  2J16 B;  3QKQ A;  4HJQ A;  1YGR A;  5BZZ A;  3S3E A;  2NV5 A;  1JLN A;  2I75 A;  1PTV A;  5KA0 A;  1OHE A;  4NWF A;  2F6T A;  2M3V A;  2ZMM A;  4GWF A;  3EU0 A;  3BLU A;  4CVK A;  1WCH A;  1C84 A;  4J51 A;  2CM3 A;  5A5E A;  2HY3 A;  4QF5 A;  1VHR A;  4YR8 B;  2CNE A;  2FJM A;  5EHR A;  1I9T A;  1GWZ A;  5KA2 A;  1WAX A;  3QCG A;  1OEO X;  3GXH A;  3QCD A;  4ERC A;  2BGE A;  2GC5 A;  1G7F A;  5K9W A;  2H02 A;  4WU2 A;  4RKK A;  1FQ1 A;  2C7S A;  2F6Y A;  2P4D A;  4RI4 A;  4BPC A;  1C85 A;  1D5R A;  4GFV A;  2I6J A;  3S3F A;  2JJD A;  3I7Z A;  3V0J A;  1PXH A;  1T48 A;  5I6V A;  1JBV A;  1Q1M A;  2F6V A;  2R0B A;  1FGS A;  1LYV A;  4RH5 A;  2MBC A;  5HDE A;  4ZN5 A;  5KAD A;  2G59 A;  3UAG A;  3M4U A;  3QCN A;  1C87 A;  2PT0 A;  2CM2 A;  4OHL A;  1M3G A;  4PVG A;  3F9B A;  1KAV A;  1XXV A;  2AZR A;  2I6P A;  5A5F A;  2QCT A;  2J16 A;  2BIJ A;  3LJ8 A;  4NX8 A;  3O3L A;  2I42 A;  3QCC A;  4JNB A;  3QCK A;  4QBE A;  2H4V A;  2GC6 A;  1UAG A;  2Q05 A;  2UUO A;  4OHI A;  2I3R A;  1L8K A;  4OHE A;  2RF6 A;  1LQF A;  3I36 A;  4RH9 A;  3ZV2 A;  3O4S A;  1ECV A;  3U96 A;  1OEU A;  1G7G A;  2PBN A;  2IMG A;  4NWG A;  3EB1 A;  2CMA A;  4CVL A;  1X24 A;  2I1Y A;  3D1Q A;  2F46 A;  3ZL8 A;  2HVL A;  3ZMQ A;  5K22 A;  3ZM2 A;  4BUB A;  2CM7 A;  4D3R A;  4YAA A;  5KAB A;  5KA8 A;  2H4K A;  5KAC A;  1XXP A;  4QAP A;  2HXP A;  2VEV A;  1LAR A;  2I4H A;  5EHP A;  3A5J A;  5GTJ A;  2QDM A;  1I9S A;  2CMB A;  3S4O A;  2GCA A;  4Z6B A;  1NZ7 A;  1R6H A;  1U24 A;  2I6M A;  1Q6J A;  1T4J A;  2PA5 A;  2H04 A;  4H34 A;  4BUC A;  2OZ5 A;  3F9A A;  4GS0 A;  4S0G A;  4RDD A;  1V3A A;  1YTN A;  1RPM A;  3LK7 A;  5J8R A;  2OOQ A;  3CWE A;  2NLK A;  1PYN A;  2HC1 A;  5IBM A;  4WOH A;  1XRI A;  5IBS A;  2QEP A;  1FPZ A;  3V0F A;  1XM2 A;  2BV5 A;  2VOR A;  2FH7 A;  3EZZ A;  3BLT A;  4JBC A;  3QCE A;  3S3H A;  4B04 A;  1P15 A;  1EEH A;  2A8B A; 
#chains in the Genus database with same CATH homology
 4ICZ A;  1Q6M A;  2I6O A;  3V0E A;  3O4T A;  4RHG A;  4D3P A;  2HCM A;  3RGQ A;  1RXD A;  3RO1 A;  2VEY A;  3H2X A;  3O5X A;  3S4E A;  1OHC A;  3GXG A;  4ZRT A;  1MKP A;  1PTU A;  2B3O A;  2H03 A;  4QAH A;  5AWX A;  1OEM X;  1GFY A;  4R30 A;  4GRY A;  1OES A;  2B49 A;  4NYH A;  4DGP A;  1J4X A;  3B7O A;  3D1H A;  2C46 A;  2FJN A;  2B4S A;  3QCF A;  3N0A A;  2HC2 A;  2VEX A;  1ZCK A;  4Y2E A;  5BZX A;  2AHS A;  4BJO A;  4R0T A;  3F81 A;  2ESB A;  4PYH A;  2I6I A;  2F6F A;  3QCB A;  2VEU A;  3AWE A;  3ZM0 A;  4ZI4 A;  1NWE A;  1FPR A;  2QDP A;  3PS5 A;  3F99 A;  5K24 A;  1Q6N A;  5KA4 A;  4QUM A;  2B4P A;  2OC3 A;  3CM3 A;  1U26 A;  5KA3 A;  2QBP A;  3A5K A;  5K23 A;  3D9C A;  1L8G A;  5KA9 A;  1PTY A;  1Q6T A;  2Y96 A;  2YDU A;  4DGX A;  4MBB A;  1ZZW A;  5M43 A;  1G1H A;  4QUN A;  2QBR A;  5BX1 A;  1NL9 A;  5KAA A;  3BRH A;  1YTW A;  3AWF A;  3QCH A;  4KI9 A;  4R0S A;  1XBO A;  1U25 A;  2F6Z A;  4RI5 A;  3V0G A;  3QCJ A;  2CMC A;  2B07 A;  2QDC A;  2WGP A;  2B4O A;  5BUG A;  3ZM3 A;  1YTS A;  1AAX A;  1YWF A;  4NND A;  2VEW A;  1EEN A;  2NZ6 A;  2I4E A;  3MMJ A;  4GE2 A;  1WRM A;  4HRF A;  3SR9 A;  1T49 A;  4GE5 A;  1C86 A;  1ONZ A;  4WU3 A;  4OHH A;  2GJT A;  2A3K A;  1NWL A;  2NTA A;  3QCL A;  1PA1 A;  2E0T A;  2HNQ A;  4WTY A;  3MOW A;  4D3Q A;  5MMZ B;  4H1O A;  2CNF A;  2CNI A;  3ZMP A;  1C83 A;  4JMJ A;  3AWG A;  5K25 A;  1BZJ A;  1SUG A;  3QKP A;  2SHP A;  2BGD A;  3V0I A;  3MOZ A;  1QXK A;  1PH0 A;  2NT7 A;  4GFU A;  1Q6P A;  2Y2F A;  3OLR A;  3V0D A;  2HB1 A;  3D42 A;  2ZN7 A;  2J17 A;  4KYQ A;  2GP0 A;  1EEO A;  2F71 A;  1OEV A;  2Q47 A;  2GWO A;  3D1O A;  3RGO A;  2I5X A;  1YPT A;  4KYR A;  3RZ2 A;  2HNP A;  2CM8 A;  3QCM A;  4I8N A;  1C88 A;  2DXP A;  1G1F A;  3BM8 A;  2I3U A;  1YZ4 A;  1G1G A;  3F41 A;  1NNY A;  4GE6 A;  2F70 A;  2QBS A;  1ZC0 A;  2F6W A;  3EAX A;  4TVV A;  2I4G A;  2G6Z A;  1JF7 A;  2CNG A;  1YFO A;  3QCI A;  2PQ5 A;  4OHD A;  2OUD A;  4HJP A;  1ONY A;  3D44 A;  2CFV A;  3OMH A;  1PA9 A;  3SME A;  1YN9 A;  2NT2 A;  1PTT A;  1G4W R;  2H4G A;  1OHD A;  1BZC A;  1BZH A;  1ZCL A;  2PSZ A;  4IKC A;  4QBW A;  1I57 A;  2B4U A;  1OET A;  1A5Y A;  1YGU A;  2P6X A;  2CJZ A;  5KA7 A;  3V0H A;  5K9V A;  2BZL A;  3O4U A;  2CNH A;  3EMU A;  4Y14 A;  2PI7 A;  1KAK A;  5KA1 A;  4GRZ A;  3NME A;  2QBQ A;  1NO6 A;  1QZ0 A;  4JMK A;  4AZ1 A;  2QCJ A;  1G4U S;  3I80 A;  3S3K A;  1Q6S A;  3ZM1 A;  5LXQ B;  2J16 B;  3QKQ A;  4HJQ A;  1YGR A;  5BZZ A;  3S3E A;  2NV5 A;  1JLN A;  2I75 A;  1PTV A;  5KA0 A;  1OHE A;  4NWF A;  2F6T A;  2M3V A;  2ZMM A;  4GWF A;  3EU0 A;  3BLU A;  1WCH A;  1C84 A;  4J51 A;  2CM3 A;  2HY3 A;  1VHR A;  4YR8 B;  2CNE A;  2FJM A;  5EHR A;  1I9T A;  1GWZ A;  5KA2 A;  1WAX A;  3QCG A;  1OEO X;  3GXH A;  3QCD A;  4ERC A;  2BGE A;  1G7F A;  5K9W A;  2H02 A;  4WU2 A;  4RKK A;  1FQ1 A;  2C7S A;  2F6Y A;  2P4D A;  4RI4 A;  4BPC A;  1C85 A;  1D5R A;  4GFV A;  2I6J A;  3S3F A;  2JJD A;  3I7Z A;  3V0J A;  1PXH A;  1T48 A;  5I6V A;  1Q1M A;  2F6V A;  2R0B A;  1LYV A;  4RH5 A;  2MBC A;  5HDE A;  4ZN5 A;  5KAD A;  2G59 A;  3M4U A;  3QCN A;  1C87 A;  2PT0 A;  2CM2 A;  4OHL A;  1M3G A;  4PVG A;  3F9B A;  1KAV A;  1XXV A;  2AZR A;  2I6P A;  2QCT A;  2J16 A;  2BIJ A;  3LJ8 A;  4NX8 A;  3O3L A;  2I42 A;  3QCC A;  4JNB A;  3QCK A;  4QBE A;  2H4V A;  2Q05 A;  4OHI A;  2I3R A;  1L8K A;  4OHE A;  2RF6 A;  1LQF A;  3I36 A;  4RH9 A;  3ZV2 A;  3O4S A;  1ECV A;  3U96 A;  1OEU A;  1G7G A;  2PBN A;  2IMG A;  4NWG A;  3EB1 A;  2CMA A;  1X24 A;  2I1Y A;  3D1Q A;  2F46 A;  2HVL A;  3ZMQ A;  5K22 A;  3ZM2 A;  2CM7 A;  4D3R A;  4YAA A;  5KAB A;  5KA8 A;  2H4K A;  5KAC A;  1XXP A;  4QAP A;  2HXP A;  2VEV A;  1LAR A;  2I4H A;  5EHP A;  3A5J A;  5GTJ A;  2QDM A;  1I9S A;  2CMB A;  3S4O A;  4Z6B A;  1NZ7 A;  1R6H A;  1U24 A;  2I6M A;  1Q6J A;  1T4J A;  2PA5 A;  2H04 A;  4H34 A;  2OZ5 A;  3F9A A;  4GS0 A;  4S0G A;  4RDD A;  1V3A A;  1YTN A;  1RPM A;  5J8R A;  2OOQ A;  3CWE A;  2NLK A;  1PYN A;  2HC1 A;  5IBM A;  4WOH A;  1XRI A;  5IBS A;  2QEP A;  1FPZ A;  3V0F A;  1XM2 A;  2BV5 A;  2FH7 A;  3EZZ A;  3BLT A;  4JBC A;  3QCE A;  3S3H A;  4B04 A;  1P15 A;  2A8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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