2P4DA

Structure-assisted discovery of variola major h1 phosphatase inhibitors
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
163
structure length
163
Chain Sequence
SLYKYLLLRSTGDMRRAKSPTIMTRVTNNVYLGNYKNAMNAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCVAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-assisted discovery of variola major H1 phosphatase inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Variola virus
molecule keywords Dual specificity protein phosphatase
total genus 57
structure length 163
sequence length 163
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2p4dA00
4RI5A 2NT7A 2BV5A 3N0AA 4R0TA 1XXVA 1C84A 3S4OA 4ICZA 2G6ZA 1PTUA 2GP0A 3QCEA 3MOZA 1PTVA 4WU2A 5KA0A 2HXPA 3D1QA 3ZV2A 2PQ5A 1LYVA 5KA2A 3QCHA 4JBCA 5BZZA 1WAXA 2HNPA 1G1HA 2QBQA 1FPRA 1G1FA 1T4JA 2CNIA 3QCDA 1M3GA 2H4VA 3ZM0A 3F9BA 4RH5A 2E0TA 1YFOA 3D42A 4ZRTA 3M4UA 3I36A 3QKPA 3QCMA 2PA5A 1JF7A 2H4GA 1SUGA 5EHPA 3QCKA 2M3VA 1G7FA 1OHEA 3RO1A 4RHGA 4D3QA 2J17A 4YAAA 2HY3A 4KYRA 4AZ1A 1OETA 2VEXA 4ZN5A 4OHLA 3O5XA 2QCJA 2I4GA 3BLTA 2CNFA 1Q6SA 2DXPA 2NZ6A 2FJNA 5BX1A 1Q6PA 3S4EA 1L8GA 4BJOA 2F70A 1GFYA 1Q6TA 3SMEA 3ZM2A 1XM2A 4TVVA 3EU0A 2HCMA 2MBCA 5KAAA 1LQFA 2AHSA 1NNYA 4GRZA 4KYQA 1NWEA 4GFUA 1C88A 3QKQA 4H34A 2CNGA 2CJZA 1G4WR 5KADA 3EAXA 1I9SA 2CM8A 2FH7A 2PT0A 2NV5A 2F46A 3AWGA 5AWXA 4RDDA 3S3HA 3S3KA 5KA3A 4GFVA 1V3AA 4QAPA 1YPTA 4OHDA 1Q6MA 3NMEA 2B3OA 2CNEA 4WU3A 1ZC0A 2F6ZA 4GS0A 2QBSA 3SR9A 2HNQA 4PVGA 4Y14A 5IBMA 2I42A 1OEUA 5BUGA 2P4DA 5M43A 3U96A 3O3LA 4JMKA 2PI7A 2I6IA 1YTNA 2BZLA 3V0GA 1U26A 5KA9A 3V0JA 2BGEA 1R6HA 2NT2A 2Q47A 4QUNA 2I6PA 4Z6BA 1OEVA 3QCJA 3RGQA 1BZCA 1YTWA 4NX8A 5KA8A 1ECVA 3GXGA 2YDUA 5HDEA 3V0HA 3ZM1A 2OUDA 5K25A 2ZMMA 2P6XA 4RH9A 2Y96A 2AZRA 3GXHA 4B04A 3AWFA 2OC3A 2WGPA 1ONZA 1ONYA 4GE6A 1EENA 5I6VA 3LJ8A 1C83A 4R30A 2J16B 5K24A 1GWZA 2A3KA 1OESA 5KACA 2QBRA 1QXKA 2Q05A 1X24A 5KABA 2C7SA 3MMJA 1U25A 4GE5A 3MOWA 3H2XA 4BPCA 4Y2EA 2CMAA 2F6FA 2J16A 2ESBA 2I6JA 1NO6A 2I6MA 2QBPA 4R0SA 4D3PA 1C85A 1RXDA 3B7OA 1QZ0A 2GWOA 5MMZB 2QDPA 5IBSA 4GWFA 3BM8A 4D3RA 2IMGA 5EHRA 1FQ1A 3EZZA 3ZM3A 3EB1A 3AWEA 5K22A 1I57A 1BZHA 2I1YA 2H02A 4HRFA 4ZI4A 2HVLA 3F9AA 4RI4A 2F6VA 1KAVA 2I6OA 2BGDA 2QCTA 4S0GA 2H04A 4QUMA 3D1OA 5KA4A 3V0DA 3F41A 2CMBA 2I5XA 2PBNA 3ZMPA 2VEYA 3OLRA 3RGOA 3OMHA 1D5RA 2BIJA 4QBEA 1OHDA 3QCFA 3V0IA 4QBWA 4IKCA 4OHEA 2QDMA 2NLKA 2HC1A 1PA9A 1ZCLA 3S3FA 2F6WA 2C46A 2QEPA 1KAKA 1ZCKA 4PYHA 4YR8B 5K23A 1I9TA 1OEMX 2B4PA 1A5YA 1RPMA 1J4XA 1LARA 2F71A 2A8BA 2I3RA 2CMCA 1OHCA 3V0EA 2B4UA 3A5KA 1XBOA 1NZ7A 4MBBA 1T48A 3O4SA 1PTYA 3O4TA 1PA1A 2F6YA 4JMJA 3S3EA 3BLUA 2CFVA 3RZ2A 4J51A 4H1OA 3F99A 5K9WA 3D9CA 1BZJA 1VHRA 2GJTA 2F6TA 4HJQA 2I4EA 4QAHA 4DGPA 4RKKA 2B4SA 2G59A 2VEUA 3QCBA 3QCNA 1YN9A 2HB1A 3I80A 4OHIA 1Q1MA 4HJPA 4I8NA 1G1GA 1JLNA 2CM3A 2FJMA 1AAXA 1PTTA 3QCCA 3A5JA 3ZMQA 1P15A 2RF6A 3D44A 2I3UA 3V0FA 1PXHA 1EEOA 2JJDA 2OZ5A 5LXQB 3QCIA 1NWLA 1FPZA 4GRYA 1XXPA 1YWFA 3D1HA 2VEWA 4JNBA 1G4US 1YGRA 3O4UA 4KI9A 5K9VA 4OHHA 1NL9A 3PS5A 2I75A 2PSZA 1C87A 4WOHA 2I4HA 1U24A 4DGXA 3CM3A 2B49A 5J8RA 5KA1A 2Y2FA 2SHPA 3BRHA 3QCGA 4NWGA 2B4OA 3CWEA 3F81A 1PYNA 2H03A 3QCLA 2OOQA 2VEVA 3EMUA 4NWFA 2CM7A 2ZN7A 1YGUA 4GE2A 2CNHA 1WRMA 1G7GA 4NYHA 2R0BA 2H4KA 1Q6NA 1YZ4A 1ZZWA 4NNDA 2HC2A 1XRIA 5GTJA 1T49A 2NTAA 2B07A 1C86A 2QDCA 1PH0A 4WTYA 2CM2A 3I7ZA 5BZXA 1WCHA 1YTSA 5KA7A 1L8KA 1OEOX 1MKPA 1Q6JA 4ERCA
chains in the Genus database with same CATH superfamily
4RI5A 2NT7A 2BV5A 3N0AA 4BUCA 4R0TA 1XXVA 1C84A 1GQQA 3S4OA 4ICZA 2G6ZA 1JBWA 1PTUA 2GP0A 3QCEA 3MOZA 1PTVA 3NRSA 4WU2A 5KA0A 2HXPA 4UAGA 3D1QA 3ZV2A 2PQ5A 1LYVA 4BUBA 1UAGA 5KA2A 3QCHA 4JBCA 5BZZA 1WAXA 2HNPA 1G1HA 2QBQA 1FPRA 1G1FA 1T4JA 2CNIA 3QCDA 1M3GA 4CVMA 2H4VA 3ZM0A 3F9BA 4RH5A 2E0TA 1YFOA 3D42A 1J6UA 4ZRTA 3M4UA 3I36A 3QKPA 4QDIA 2VTDA 3QCMA 2PA5A 1JF7A 2H4GA 1SUGA 5EHPA 3QCKA 2M3VA 1G7FA 3LK7A 1OHEA 3RO1A 4RHGA 4D3QA 2J17A 3PYZA 4YAAA 2HY3A 4KYRA 4AZ1A 1OETA 2VEXA 4ZN5A 4OHLA 1FGSA 3O5XA 2QCJA 2I4GA 3BLTA 2CNFA 1Q6SA 2DXPA 2NZ6A 2FJNA 5BX1A 1Q6PA 3S4EA 1L8GA 4BJOA 2F70A 4QF5A 1GFYA 1Q6TA 3SMEA 3ZM2A 1XM2A 4TVVA 3EU0A 2HCMA 2MBCA 5KAAA 1LQFA 2AHSA 1NNYA 4GRZA 2VOSA 4KYQA 1NWEA 4GFUA 1C88A 3QKQA 4H34A 2CNGA 2CJZA 1G4WR 5KADA 3EAXA 1I9SA 2CM8A 2FH7A 2PT0A 2NV5A 2F46A 3AWGA 5AWXA 4RDDA 3S3HA 3S3KA 5KA3A 4GFVA 1V3AA 4QAPA 1YPTA 4OHDA 1Q6MA 3NMEA 1E8CA 2B3OA 2CNEA 2VORA 4WU3A 2Y66A 1ZC0A 2F6ZA 4GS0A 2QBSA 3SR9A 2HNQA 4PVGA 4Y14A 5IBMA 2I42A 1OEUA 5BUGA 2P4DA 5M43A 3U96A 3O3LA 4JMKA 2PI7A 2I6IA 2AM1A 1YTNA 2BZLA 3V0GA 1U26A 5KA9A 3V0JA 2BGEA 1R6HA 2NT2A 2Q47A 4QUNA 2I6PA 4Z6BA 1OEVA 3QCJA 3N2AA 3RGQA 1BZCA 1YTWA 4NX8A 5KA8A 1ECVA 3GXGA 2YDUA 5HDEA 3V0HA 3ZM1A 1O5ZA 2GC6A 2OUDA 5K25A 2ZMMA 2P6XA 4RH9A 2Y96A 2AZRA 3GXHA 2XJAA 4B04A 3AWFA 2OC3A 2WGPA 1ONZA 1ONYA 4GE6A 1EENA 1JBVA 5I6VA 3LJ8A 1C83A 4R30A 2J16B 5K24A 1GWZA 2A3KA 1OESA 5KACA 2QBRA 2GCAA 5A5FA 1QXKA 2Q05A 1X24A 5KABA 2C7SA 3MMJA 1U25A 4GE5A 3ZM5A 3MOWA 3H2XA 4BPCA 4Y2EA 2CMAA 2F6FA 2J16A 2ESBA 2I6JA 1NO6A 2I6MA 2QBPA 4R0SA 4D3PA 1C85A 1RXDA 3B7OA 2WTZA 1QZ0A 2GWOA 5MMZB 2QDPA 2JFGA 5IBSA 4GWFA 3BM8A 4D3RA 2IMGA 5EHRA 1FQ1A 3EZZA 3ZM3A 3EB1A 3AWEA 5K22A 4CVKA 1I57A 1BZHA 2I1YA 2H02A 4HRFA 1W78A 4ZI4A 2HVLA 3F9AA 4RI4A 2F6VA 1KAVA 2I6OA 2BGDA 2QCTA 4S0GA 2H04A 4QUMA 3D1OA 5KA4A 3V0DA 1GG4A 3F41A 2CMBA 3MVNA 2I5XA 2PBNA 3ZMPA 2VEYA 2Y68A 3OLRA 2UUPA 2Y1OA 3RGOA 3OMHA 1D5RA 2BIJA 4QBEA 1OHDA 1P3DA 4C13A 3QCFA 3V0IA 4QBWA 4IKCA 4OHEA 2QDMA 2NLKA 2GC5A 2HC1A 1PA9A 1ZCLA 3S3FA 2JFHA 2F6WA 2C46A 2QEPA 2GCBA 1KAKA 1ZCKA 4PYHA 4YR8B 5K23A 1I9TA 1OEMX 2B4PA 1A5YA 1RPMA 1J4XA 1LARA 2F71A 2A8BA 1E0DA 2I3RA 2CMCA 2XPCA 1OHCA 3V0EA 2B4UA 3A5KA 1XBOA 1NZ7A 4MBBA 1T48A 3O4SA 1PTYA 3O4TA 1PA1A 2F6YA 4JMJA 3S3EA 3BLUA 2CFVA 3RZ2A 4J51A 4H1OA 3F99A 5K9WA 3D9CA 1BZJA 1VHRA 2GJTA 3ZL8A 2F6TA 4HJQA 2I4EA 4QAHA 4DGPA 4RKKA 4HV4A 2B4SA 2G59A 2UUOA 4C12A 2VEUA 3QCBA 3QCNA 1YN9A 2HB1A 3I80A 4OHIA 2X5OA 1Q1MA 4HJPA 4I8NA 3HN7A 1G1GA 1JLNA 2CM3A 2FJMA 1AAXA 1PTTA 3QCCA 3A5JA 3ZMQA 1P15A 2RF6A 3D44A 2I3UA 3V0FA 2JFFA 1PXHA 1EEOA 2JJDA 2OZ5A 5LXQB 3QCIA 1NWLA 1FPZA 4GRYA 1XXPA 1YWFA 3D1HA 2VEWA 4JNBA 1G4US 1YGRA 3O4UA 4KI9A 5K9VA 4OHHA 1NL9A 3PS5A 2I75A 2PSZA 1C87A 4WOHA 2I4HA 1U24A 4DGXA 3CM3A 2B49A 5J8RA 5KA1A 2Y2FA 2SHPA 3BRHA 3QCGA 2UAGA 4NWGA 2B4OA 3CWEA 3F81A 1PYNA 2H03A 3QCLA 3UAGA 2OOQA 2VEVA 3EMUA 4NWFA 2VTEA 2CM7A 2F00A 2ZN7A 2WJPA 1YGUA 4GE2A 1W7KA 2CNHA 1WRMA 1G7GA 3ZM6A 4NYHA 2R0BA 2H4KA 2Y67A 1Q6NA 1YZ4A 1ZZWA 4NNDA 2HC2A 3QCZA 4ZIYA 1XRIA 5GTJA 1T49A 4CVLA 2NTAA 2B07A 1C86A 2QDCA 1PH0A 4WTYA 2CM2A 3I7ZA 5BZXA 1GQYA 1WCHA 1YTSA 2AM2A 5KA7A 1L8KA 1P31A 1OEOX 1MKPA 1EEHA 1Q6JA 5A5EA 4ERCA
chains in the Genus database with same CATH topology
4RI5A 2NT7A 2BV5A 3N0AA 4R0TA 1XXVA 1C84A 3S4OA 4ICZA 2G6ZA 1PTUA 2GP0A 3QCEA 3MOZA 1PTVA 4WU2A 5KA0A 2HXPA 3D1QA 3ZV2A 2PQ5A 1LYVA 5KA2A 3QCHA 4JBCA 5BZZA 1WAXA 2HNPA 1G1HA 2QBQA 1FPRA 1G1FA 1T4JA 2CNIA 3QCDA 1M3GA 2H4VA 3ZM0A 3F9BA 4RH5A 2E0TA 1YFOA 3D42A 4ZRTA 3M4UA 3I36A 3QKPA 3QCMA 2PA5A 1JF7A 2H4GA 1SUGA 5EHPA 3QCKA 2M3VA 1G7FA 1OHEA 3RO1A 4RHGA 4D3QA 2J17A 4YAAA 2HY3A 4KYRA 4AZ1A 1OETA 2VEXA 4ZN5A 4OHLA 3O5XA 2QCJA 2I4GA 3BLTA 2CNFA 1Q6SA 2DXPA 2NZ6A 2FJNA 5BX1A 1Q6PA 3S4EA 1L8GA 4BJOA 2F70A 1GFYA 1Q6TA 3SMEA 3ZM2A 1XM2A 4TVVA 3EU0A 2HCMA 2MBCA 5KAAA 1LQFA 2AHSA 1NNYA 4GRZA 4KYQA 1NWEA 4GFUA 1C88A 3QKQA 4H34A 2CNGA 2CJZA 1G4WR 5KADA 3EAXA 1I9SA 2CM8A 2FH7A 2PT0A 2NV5A 2F46A 3AWGA 5AWXA 4RDDA 3S3HA 3S3KA 5KA3A 4GFVA 1V3AA 4QAPA 1YPTA 4OHDA 1Q6MA 3NMEA 2B3OA 2CNEA 4WU3A 1ZC0A 2F6ZA 4GS0A 2QBSA 3SR9A 2HNQA 4PVGA 4Y14A 5IBMA 2I42A 1OEUA 5BUGA 2P4DA 5M43A 3U96A 3O3LA 4JMKA 2PI7A 2I6IA 1YTNA 2BZLA 3V0GA 1U26A 5KA9A 3V0JA 2BGEA 1R6HA 2NT2A 2Q47A 4QUNA 2I6PA 4Z6BA 1OEVA 3QCJA 3RGQA 1BZCA 1YTWA 4NX8A 5KA8A 1ECVA 3GXGA 2YDUA 5HDEA 3V0HA 3ZM1A 2OUDA 5K25A 2ZMMA 2P6XA 4RH9A 2Y96A 2AZRA 3GXHA 4B04A 3AWFA 2OC3A 2WGPA 1ONZA 1ONYA 4GE6A 1EENA 5I6VA 3LJ8A 1C83A 4R30A 2J16B 5K24A 1GWZA 2A3KA 1OESA 5KACA 2QBRA 1QXKA 2Q05A 1X24A 5KABA 2C7SA 3MMJA 1U25A 4GE5A 3MOWA 3H2XA 4BPCA 4Y2EA 2CMAA 2F6FA 2J16A 2ESBA 2I6JA 1NO6A 2I6MA 2QBPA 4R0SA 4D3PA 1C85A 1RXDA 3B7OA 1QZ0A 2GWOA 5MMZB 2QDPA 5IBSA 4GWFA 3BM8A 4D3RA 2IMGA 5EHRA 1FQ1A 3EZZA 3ZM3A 3EB1A 3AWEA 5K22A 1I57A 1BZHA 2I1YA 2H02A 4HRFA 4ZI4A 2HVLA 3F9AA 4RI4A 2F6VA 1KAVA 2I6OA 2BGDA 2QCTA 4S0GA 2H04A 4QUMA 3D1OA 5KA4A 3V0DA 3F41A 2CMBA 2I5XA 2PBNA 3ZMPA 2VEYA 3OLRA 3RGOA 3OMHA 1D5RA 2BIJA 4QBEA 1OHDA 3QCFA 3V0IA 4QBWA 4IKCA 4OHEA 2QDMA 2NLKA 2HC1A 1PA9A 1ZCLA 3S3FA 2F6WA 2C46A 2QEPA 1KAKA 1ZCKA 4PYHA 4YR8B 5K23A 1I9TA 1OEMX 2B4PA 1A5YA 1RPMA 1J4XA 1LARA 2F71A 2A8BA 2I3RA 2CMCA 1OHCA 3V0EA 2B4UA 3A5KA 1XBOA 1NZ7A 4MBBA 1T48A 3O4SA 1PTYA 3O4TA 1PA1A 2F6YA 4JMJA 3S3EA 3BLUA 2CFVA 3RZ2A 4J51A 4H1OA 3F99A 5K9WA 3D9CA 1BZJA 1VHRA 2GJTA 2F6TA 4HJQA 2I4EA 4QAHA 4DGPA 4RKKA 2B4SA 2G59A 2VEUA 3QCBA 3QCNA 1YN9A 2HB1A 3I80A 4OHIA 1Q1MA 4HJPA 4I8NA 1G1GA 1JLNA 2CM3A 2FJMA 1AAXA 1PTTA 3QCCA 3A5JA 3ZMQA 1P15A 2RF6A 3D44A 2I3UA 3V0FA 1PXHA 1EEOA 2JJDA 2OZ5A 5LXQB 3QCIA 1NWLA 1FPZA 4GRYA 1XXPA 1YWFA 3D1HA 2VEWA 4JNBA 1G4US 1YGRA 3O4UA 4KI9A 5K9VA 4OHHA 1NL9A 3PS5A 2I75A 2PSZA 1C87A 4WOHA 2I4HA 1U24A 4DGXA 3CM3A 2B49A 5J8RA 5KA1A 2Y2FA 2SHPA 3BRHA 3QCGA 4NWGA 2B4OA 3CWEA 3F81A 1PYNA 2H03A 3QCLA 2OOQA 2VEVA 3EMUA 4NWFA 2CM7A 2ZN7A 1YGUA 4GE2A 2CNHA 1WRMA 1G7GA 4NYHA 2R0BA 2H4KA 1Q6NA 1YZ4A 1ZZWA 4NNDA 2HC2A 1XRIA 5GTJA 1T49A 2NTAA 2B07A 1C86A 2QDCA 1PH0A 4WTYA 2CM2A 3I7ZA 5BZXA 1WCHA 1YTSA 5KA7A 1L8KA 1OEOX 1MKPA 1Q6JA 4ERCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RI5 A;  2NT7 A;  2BV5 A;  3N0A A;  4R0T A;  1XXV A;  1C84 A;  3S4O A;  4ICZ A;  2G6Z A;  1PTU A;  2GP0 A;  3QCE A;  3MOZ A;  1PTV A;  4WU2 A;  5KA0 A;  2HXP A;  3D1Q A;  3ZV2 A;  2PQ5 A;  1LYV A;  5KA2 A;  3QCH A;  4JBC A;  5BZZ A;  1WAX A;  2HNP A;  1G1H A;  2QBQ A;  1FPR A;  1G1F A;  1T4J A;  2CNI A;  3QCD A;  1M3G A;  2H4V A;  3ZM0 A;  3F9B A;  4RH5 A;  2E0T A;  1YFO A;  3D42 A;  4ZRT A;  3M4U A;  3I36 A;  3QKP A;  3QCM A;  2PA5 A;  1JF7 A;  2H4G A;  1SUG A;  5EHP A;  3QCK A;  2M3V A;  1G7F A;  1OHE A;  3RO1 A;  4RHG A;  4D3Q A;  2J17 A;  4YAA A;  2HY3 A;  4KYR A;  4AZ1 A;  1OET A;  2VEX A;  4ZN5 A;  4OHL A;  3O5X A;  2QCJ A;  2I4G A;  3BLT A;  2CNF A;  1Q6S A;  2DXP A;  2NZ6 A;  2FJN A;  5BX1 A;  1Q6P A;  3S4E A;  1L8G A;  4BJO A;  2F70 A;  1GFY A;  1Q6T A;  3SME A;  3ZM2 A;  1XM2 A;  4TVV A;  3EU0 A;  2HCM A;  2MBC A;  5KAA A;  1LQF A;  2AHS A;  1NNY A;  4GRZ A;  4KYQ A;  1NWE A;  4GFU A;  1C88 A;  3QKQ A;  4H34 A;  2CNG A;  2CJZ A;  1G4W R;  5KAD A;  3EAX A;  1I9S A;  2CM8 A;  2FH7 A;  2PT0 A;  2NV5 A;  2F46 A;  3AWG A;  5AWX A;  4RDD A;  3S3H A;  3S3K A;  5KA3 A;  4GFV A;  1V3A A;  4QAP A;  1YPT A;  4OHD A;  1Q6M A;  3NME A;  2B3O A;  2CNE A;  4WU3 A;  1ZC0 A;  2F6Z A;  4GS0 A;  2QBS A;  3SR9 A;  2HNQ A;  4PVG A;  4Y14 A;  5IBM A;  2I42 A;  1OEU A;  5BUG A;  2P4D A;  5M43 A;  3U96 A;  3O3L A;  4JMK A;  2PI7 A;  2I6I A;  1YTN A;  2BZL A;  3V0G A;  1U26 A;  5KA9 A;  3V0J A;  2BGE A;  1R6H A;  2NT2 A;  2Q47 A;  4QUN A;  2I6P A;  4Z6B A;  1OEV A;  3QCJ A;  3RGQ A;  1BZC A;  1YTW A;  4NX8 A;  5KA8 A;  1ECV A;  3GXG A;  2YDU A;  5HDE A;  3V0H A;  3ZM1 A;  2OUD A;  5K25 A;  2ZMM A;  2P6X A;  4RH9 A;  2Y96 A;  2AZR A;  3GXH A;  4B04 A;  3AWF A;  2OC3 A;  2WGP A;  1ONZ A;  1ONY A;  4GE6 A;  1EEN A;  5I6V A;  3LJ8 A;  1C83 A;  4R30 A;  2J16 B;  5K24 A;  1GWZ A;  2A3K A;  1OES A;  5KAC A;  2QBR A;  1QXK A;  2Q05 A;  1X24 A;  5KAB A;  2C7S A;  3MMJ A;  1U25 A;  4GE5 A;  3MOW A;  3H2X A;  4BPC A;  4Y2E A;  2CMA A;  2F6F A;  2J16 A;  2ESB A;  2I6J A;  1NO6 A;  2I6M A;  2QBP A;  4R0S A;  4D3P A;  1C85 A;  1RXD A;  3B7O A;  1QZ0 A;  2GWO A;  5MMZ B;  2QDP A;  5IBS A;  4GWF A;  3BM8 A;  4D3R A;  2IMG A;  5EHR A;  1FQ1 A;  3EZZ A;  3ZM3 A;  3EB1 A;  3AWE A;  5K22 A;  1I57 A;  1BZH A;  2I1Y A;  2H02 A;  4HRF A;  4ZI4 A;  2HVL A;  3F9A A;  4RI4 A;  2F6V A;  1KAV A;  2I6O A;  2BGD A;  2QCT A;  4S0G A;  2H04 A;  4QUM A;  3D1O A;  5KA4 A;  3V0D A;  3F41 A;  2CMB A;  2I5X A;  2PBN A;  3ZMP A;  2VEY A;  3OLR A;  3RGO A;  3OMH A;  1D5R A;  2BIJ A;  4QBE A;  1OHD A;  3QCF A;  3V0I A;  4QBW A;  4IKC A;  4OHE A;  2QDM A;  2NLK A;  2HC1 A;  1PA9 A;  1ZCL A;  3S3F A;  2F6W A;  2C46 A;  2QEP A;  1KAK A;  1ZCK A;  4PYH A;  4YR8 B;  5K23 A;  1I9T A;  1OEM X;  2B4P A;  1A5Y A;  1RPM A;  1J4X A;  1LAR A;  2F71 A;  2A8B A;  2I3R A;  2CMC A;  1OHC A;  3V0E A;  2B4U A;  3A5K A;  1XBO A;  1NZ7 A;  4MBB A;  1T48 A;  3O4S A;  1PTY A;  3O4T A;  1PA1 A;  2F6Y A;  4JMJ A;  3S3E A;  3BLU A;  2CFV A;  3RZ2 A;  4J51 A;  4H1O A;  3F99 A;  5K9W A;  3D9C A;  1BZJ A;  1VHR A;  2GJT A;  2F6T A;  4HJQ A;  2I4E A;  4QAH A;  4DGP A;  4RKK A;  2B4S A;  2G59 A;  2VEU A;  3QCB A;  3QCN A;  1YN9 A;  2HB1 A;  3I80 A;  4OHI A;  1Q1M A;  4HJP A;  4I8N A;  1G1G A;  1JLN A;  2CM3 A;  2FJM A;  1AAX A;  1PTT A;  3QCC A;  3A5J A;  3ZMQ A;  1P15 A;  2RF6 A;  3D44 A;  2I3U A;  3V0F A;  1PXH A;  1EEO A;  2JJD A;  2OZ5 A;  5LXQ B;  3QCI A;  1NWL A;  1FPZ A;  4GRY A;  1XXP A;  1YWF A;  3D1H A;  2VEW A;  4JNB A;  1G4U S;  1YGR A;  3O4U A;  4KI9 A;  5K9V A;  4OHH A;  1NL9 A;  3PS5 A;  2I75 A;  2PSZ A;  1C87 A;  4WOH A;  2I4H A;  1U24 A;  4DGX A;  3CM3 A;  2B49 A;  5J8R A;  5KA1 A;  2Y2F A;  2SHP A;  3BRH A;  3QCG A;  4NWG A;  2B4O A;  3CWE A;  3F81 A;  1PYN A;  2H03 A;  3QCL A;  2OOQ A;  2VEV A;  3EMU A;  4NWF A;  2CM7 A;  2ZN7 A;  1YGU A;  4GE2 A;  2CNH A;  1WRM A;  1G7G A;  4NYH A;  2R0B A;  2H4K A;  1Q6N A;  1YZ4 A;  1ZZW A;  4NND A;  2HC2 A;  1XRI A;  5GTJ A;  1T49 A;  2NTA A;  2B07 A;  1C86 A;  2QDC A;  1PH0 A;  4WTY A;  2CM2 A;  3I7Z A;  5BZX A;  1WCH A;  1YTS A;  5KA7 A;  1L8K A;  1OEO X;  1MKP A;  1Q6J A;  4ERC A; 
#chains in the Genus database with same CATH topology
 4RI5 A;  2NT7 A;  2BV5 A;  3N0A A;  4BUC A;  4R0T A;  1XXV A;  1C84 A;  1GQQ A;  3S4O A;  4ICZ A;  2G6Z A;  1JBW A;  1PTU A;  2GP0 A;  3QCE A;  3MOZ A;  1PTV A;  3NRS A;  4WU2 A;  5KA0 A;  2HXP A;  4UAG A;  3D1Q A;  3ZV2 A;  2PQ5 A;  1LYV A;  4BUB A;  1UAG A;  5KA2 A;  3QCH A;  4JBC A;  5BZZ A;  1WAX A;  2HNP A;  1G1H A;  2QBQ A;  1FPR A;  1G1F A;  1T4J A;  2CNI A;  3QCD A;  1M3G A;  4CVM A;  2H4V A;  3ZM0 A;  3F9B A;  4RH5 A;  2E0T A;  1YFO A;  3D42 A;  1J6U A;  4ZRT A;  3M4U A;  3I36 A;  3QKP A;  4QDI A;  2VTD A;  3QCM A;  2PA5 A;  1JF7 A;  2H4G A;  1SUG A;  5EHP A;  3QCK A;  2M3V A;  1G7F A;  3LK7 A;  1OHE A;  3RO1 A;  4RHG A;  4D3Q A;  2J17 A;  3PYZ A;  4YAA A;  2HY3 A;  4KYR A;  4AZ1 A;  1OET A;  2VEX A;  4ZN5 A;  4OHL A;  1FGS A;  3O5X A;  2QCJ A;  2I4G A;  3BLT A;  2CNF A;  1Q6S A;  2DXP A;  2NZ6 A;  2FJN A;  5BX1 A;  1Q6P A;  3S4E A;  1L8G A;  4BJO A;  2F70 A;  4QF5 A;  1GFY A;  1Q6T A;  3SME A;  3ZM2 A;  1XM2 A;  4TVV A;  3EU0 A;  2HCM A;  2MBC A;  5KAA A;  1LQF A;  2AHS A;  1NNY A;  4GRZ A;  2VOS A;  4KYQ A;  1NWE A;  4GFU A;  1C88 A;  3QKQ A;  4H34 A;  2CNG A;  2CJZ A;  1G4W R;  5KAD A;  3EAX A;  1I9S A;  2CM8 A;  2FH7 A;  2PT0 A;  2NV5 A;  2F46 A;  3AWG A;  5AWX A;  4RDD A;  3S3H A;  3S3K A;  5KA3 A;  4GFV A;  1V3A A;  4QAP A;  1YPT A;  4OHD A;  1Q6M A;  3NME A;  1E8C A;  2B3O A;  2CNE A;  2VOR A;  4WU3 A;  2Y66 A;  1ZC0 A;  2F6Z A;  4GS0 A;  2QBS A;  3SR9 A;  2HNQ A;  4PVG A;  4Y14 A;  5IBM A;  2I42 A;  1OEU A;  5BUG A;  2P4D A;  5M43 A;  3U96 A;  3O3L A;  4JMK A;  2PI7 A;  2I6I A;  2AM1 A;  1YTN A;  2BZL A;  3V0G A;  1U26 A;  5KA9 A;  3V0J A;  2BGE A;  1R6H A;  2NT2 A;  2Q47 A;  4QUN A;  2I6P A;  4Z6B A;  1OEV A;  3QCJ A;  3N2A A;  3RGQ A;  1BZC A;  1YTW A;  4NX8 A;  5KA8 A;  1ECV A;  3GXG A;  2YDU A;  5HDE A;  3V0H A;  3ZM1 A;  1O5Z A;  2GC6 A;  2OUD A;  5K25 A;  2ZMM A;  2P6X A;  4RH9 A;  2Y96 A;  2AZR A;  3GXH A;  2XJA A;  4B04 A;  3AWF A;  2OC3 A;  2WGP A;  1ONZ A;  1ONY A;  4GE6 A;  1EEN A;  1JBV A;  5I6V A;  3LJ8 A;  1C83 A;  4R30 A;  2J16 B;  5K24 A;  1GWZ A;  2A3K A;  1OES A;  5KAC A;  2QBR A;  2GCA A;  5A5F A;  1QXK A;  2Q05 A;  1X24 A;  5KAB A;  2C7S A;  3MMJ A;  1U25 A;  4GE5 A;  3ZM5 A;  3MOW A;  3H2X A;  4BPC A;  4Y2E A;  2CMA A;  2F6F A;  2J16 A;  2ESB A;  2I6J A;  1NO6 A;  2I6M A;  2QBP A;  4R0S A;  4D3P A;  1C85 A;  1RXD A;  3B7O A;  2WTZ A;  1QZ0 A;  2GWO A;  5MMZ B;  2QDP A;  2JFG A;  5IBS A;  4GWF A;  3BM8 A;  4D3R A;  2IMG A;  5EHR A;  1FQ1 A;  3EZZ A;  3ZM3 A;  3EB1 A;  3AWE A;  5K22 A;  4CVK A;  1I57 A;  1BZH A;  2I1Y A;  2H02 A;  4HRF A;  1W78 A;  4ZI4 A;  2HVL A;  3F9A A;  4RI4 A;  2F6V A;  1KAV A;  2I6O A;  2BGD A;  2QCT A;  4S0G A;  2H04 A;  4QUM A;  3D1O A;  5KA4 A;  3V0D A;  1GG4 A;  3F41 A;  2CMB A;  3MVN A;  2I5X A;  2PBN A;  3ZMP A;  2VEY A;  2Y68 A;  3OLR A;  2UUP A;  2Y1O A;  3RGO A;  3OMH A;  1D5R A;  2BIJ A;  4QBE A;  1OHD A;  1P3D A;  4C13 A;  3QCF A;  3V0I A;  4QBW A;  4IKC A;  4OHE A;  2QDM A;  2NLK A;  2GC5 A;  2HC1 A;  1PA9 A;  1ZCL A;  3S3F A;  2JFH A;  2F6W A;  2C46 A;  2QEP A;  2GCB A;  1KAK A;  1ZCK A;  4PYH A;  4YR8 B;  5K23 A;  1I9T A;  1OEM X;  2B4P A;  1A5Y A;  1RPM A;  1J4X A;  1LAR A;  2F71 A;  2A8B A;  1E0D A;  2I3R A;  2CMC A;  2XPC A;  1OHC A;  3V0E A;  2B4U A;  3A5K A;  1XBO A;  1NZ7 A;  4MBB A;  1T48 A;  3O4S A;  1PTY A;  3O4T A;  1PA1 A;  2F6Y A;  4JMJ A;  3S3E A;  3BLU A;  2CFV A;  3RZ2 A;  4J51 A;  4H1O A;  3F99 A;  5K9W A;  3D9C A;  1BZJ A;  1VHR A;  2GJT A;  3ZL8 A;  2F6T A;  4HJQ A;  2I4E A;  4QAH A;  4DGP A;  4RKK A;  4HV4 A;  2B4S A;  2G59 A;  2UUO A;  4C12 A;  2VEU A;  3QCB A;  3QCN A;  1YN9 A;  2HB1 A;  3I80 A;  4OHI A;  2X5O A;  1Q1M A;  4HJP A;  4I8N A;  3HN7 A;  1G1G A;  1JLN A;  2CM3 A;  2FJM A;  1AAX A;  1PTT A;  3QCC A;  3A5J A;  3ZMQ A;  1P15 A;  2RF6 A;  3D44 A;  2I3U A;  3V0F A;  2JFF A;  1PXH A;  1EEO A;  2JJD A;  2OZ5 A;  5LXQ B;  3QCI A;  1NWL A;  1FPZ A;  4GRY A;  1XXP A;  1YWF A;  3D1H A;  2VEW A;  4JNB A;  1G4U S;  1YGR A;  3O4U A;  4KI9 A;  5K9V A;  4OHH A;  1NL9 A;  3PS5 A;  2I75 A;  2PSZ A;  1C87 A;  4WOH A;  2I4H A;  1U24 A;  4DGX A;  3CM3 A;  2B49 A;  5J8R A;  5KA1 A;  2Y2F A;  2SHP A;  3BRH A;  3QCG A;  2UAG A;  4NWG A;  2B4O A;  3CWE A;  3F81 A;  1PYN A;  2H03 A;  3QCL A;  3UAG A;  2OOQ A;  2VEV A;  3EMU A;  4NWF A;  2VTE A;  2CM7 A;  2F00 A;  2ZN7 A;  2WJP A;  1YGU A;  4GE2 A;  1W7K A;  2CNH A;  1WRM A;  1G7G A;  3ZM6 A;  4NYH A;  2R0B A;  2H4K A;  2Y67 A;  1Q6N A;  1YZ4 A;  1ZZW A;  4NND A;  2HC2 A;  3QCZ A;  4ZIY A;  1XRI A;  5GTJ A;  1T49 A;  4CVL A;  2NTA A;  2B07 A;  1C86 A;  2QDC A;  1PH0 A;  4WTY A;  2CM2 A;  3I7Z A;  5BZX A;  1GQY A;  1WCH A;  1YTS A;  2AM2 A;  5KA7 A;  1L8K A;  1P31 A;  1OEO X;  1MKP A;  1EEH A;  1Q6J A;  5A5E A;  4ERC A; 
#chains in the Genus database with same CATH homology
 4RI5 A;  2NT7 A;  2BV5 A;  3N0A A;  4R0T A;  1XXV A;  1C84 A;  3S4O A;  4ICZ A;  2G6Z A;  1PTU A;  2GP0 A;  3QCE A;  3MOZ A;  1PTV A;  4WU2 A;  5KA0 A;  2HXP A;  3D1Q A;  3ZV2 A;  2PQ5 A;  1LYV A;  5KA2 A;  3QCH A;  4JBC A;  5BZZ A;  1WAX A;  2HNP A;  1G1H A;  2QBQ A;  1FPR A;  1G1F A;  1T4J A;  2CNI A;  3QCD A;  1M3G A;  2H4V A;  3ZM0 A;  3F9B A;  4RH5 A;  2E0T A;  1YFO A;  3D42 A;  4ZRT A;  3M4U A;  3I36 A;  3QKP A;  3QCM A;  2PA5 A;  1JF7 A;  2H4G A;  1SUG A;  5EHP A;  3QCK A;  2M3V A;  1G7F A;  1OHE A;  3RO1 A;  4RHG A;  4D3Q A;  2J17 A;  4YAA A;  2HY3 A;  4KYR A;  4AZ1 A;  1OET A;  2VEX A;  4ZN5 A;  4OHL A;  3O5X A;  2QCJ A;  2I4G A;  3BLT A;  2CNF A;  1Q6S A;  2DXP A;  2NZ6 A;  2FJN A;  5BX1 A;  1Q6P A;  3S4E A;  1L8G A;  4BJO A;  2F70 A;  1GFY A;  1Q6T A;  3SME A;  3ZM2 A;  1XM2 A;  4TVV A;  3EU0 A;  2HCM A;  2MBC A;  5KAA A;  1LQF A;  2AHS A;  1NNY A;  4GRZ A;  4KYQ A;  1NWE A;  4GFU A;  1C88 A;  3QKQ A;  4H34 A;  2CNG A;  2CJZ A;  1G4W R;  5KAD A;  3EAX A;  1I9S A;  2CM8 A;  2FH7 A;  2PT0 A;  2NV5 A;  2F46 A;  3AWG A;  5AWX A;  4RDD A;  3S3H A;  3S3K A;  5KA3 A;  4GFV A;  1V3A A;  4QAP A;  1YPT A;  4OHD A;  1Q6M A;  3NME A;  2B3O A;  2CNE A;  4WU3 A;  1ZC0 A;  2F6Z A;  4GS0 A;  2QBS A;  3SR9 A;  2HNQ A;  4PVG A;  4Y14 A;  5IBM A;  2I42 A;  1OEU A;  5BUG A;  2P4D A;  5M43 A;  3U96 A;  3O3L A;  4JMK A;  2PI7 A;  2I6I A;  1YTN A;  2BZL A;  3V0G A;  1U26 A;  5KA9 A;  3V0J A;  2BGE A;  1R6H A;  2NT2 A;  2Q47 A;  4QUN A;  2I6P A;  4Z6B A;  1OEV A;  3QCJ A;  3RGQ A;  1BZC A;  1YTW A;  4NX8 A;  5KA8 A;  1ECV A;  3GXG A;  2YDU A;  5HDE A;  3V0H A;  3ZM1 A;  2OUD A;  5K25 A;  2ZMM A;  2P6X A;  4RH9 A;  2Y96 A;  2AZR A;  3GXH A;  4B04 A;  3AWF A;  2OC3 A;  2WGP A;  1ONZ A;  1ONY A;  4GE6 A;  1EEN A;  5I6V A;  3LJ8 A;  1C83 A;  4R30 A;  2J16 B;  5K24 A;  1GWZ A;  2A3K A;  1OES A;  5KAC A;  2QBR A;  1QXK A;  2Q05 A;  1X24 A;  5KAB A;  2C7S A;  3MMJ A;  1U25 A;  4GE5 A;  3MOW A;  3H2X A;  4BPC A;  4Y2E A;  2CMA A;  2F6F A;  2J16 A;  2ESB A;  2I6J A;  1NO6 A;  2I6M A;  2QBP A;  4R0S A;  4D3P A;  1C85 A;  1RXD A;  3B7O A;  1QZ0 A;  2GWO A;  5MMZ B;  2QDP A;  5IBS A;  4GWF A;  3BM8 A;  4D3R A;  2IMG A;  5EHR A;  1FQ1 A;  3EZZ A;  3ZM3 A;  3EB1 A;  3AWE A;  5K22 A;  1I57 A;  1BZH A;  2I1Y A;  2H02 A;  4HRF A;  4ZI4 A;  2HVL A;  3F9A A;  4RI4 A;  2F6V A;  1KAV A;  2I6O A;  2BGD A;  2QCT A;  4S0G A;  2H04 A;  4QUM A;  3D1O A;  5KA4 A;  3V0D A;  3F41 A;  2CMB A;  2I5X A;  2PBN A;  3ZMP A;  2VEY A;  3OLR A;  3RGO A;  3OMH A;  1D5R A;  2BIJ A;  4QBE A;  1OHD A;  3QCF A;  3V0I A;  4QBW A;  4IKC A;  4OHE A;  2QDM A;  2NLK A;  2HC1 A;  1PA9 A;  1ZCL A;  3S3F A;  2F6W A;  2C46 A;  2QEP A;  1KAK A;  1ZCK A;  4PYH A;  4YR8 B;  5K23 A;  1I9T A;  1OEM X;  2B4P A;  1A5Y A;  1RPM A;  1J4X A;  1LAR A;  2F71 A;  2A8B A;  2I3R A;  2CMC A;  1OHC A;  3V0E A;  2B4U A;  3A5K A;  1XBO A;  1NZ7 A;  4MBB A;  1T48 A;  3O4S A;  1PTY A;  3O4T A;  1PA1 A;  2F6Y A;  4JMJ A;  3S3E A;  3BLU A;  2CFV A;  3RZ2 A;  4J51 A;  4H1O A;  3F99 A;  5K9W A;  3D9C A;  1BZJ A;  1VHR A;  2GJT A;  2F6T A;  4HJQ A;  2I4E A;  4QAH A;  4DGP A;  4RKK A;  2B4S A;  2G59 A;  2VEU A;  3QCB A;  3QCN A;  1YN9 A;  2HB1 A;  3I80 A;  4OHI A;  1Q1M A;  4HJP A;  4I8N A;  1G1G A;  1JLN A;  2CM3 A;  2FJM A;  1AAX A;  1PTT A;  3QCC A;  3A5J A;  3ZMQ A;  1P15 A;  2RF6 A;  3D44 A;  2I3U A;  3V0F A;  1PXH A;  1EEO A;  2JJD A;  2OZ5 A;  5LXQ B;  3QCI A;  1NWL A;  1FPZ A;  4GRY A;  1XXP A;  1YWF A;  3D1H A;  2VEW A;  4JNB A;  1G4U S;  1YGR A;  3O4U A;  4KI9 A;  5K9V A;  4OHH A;  1NL9 A;  3PS5 A;  2I75 A;  2PSZ A;  1C87 A;  4WOH A;  2I4H A;  1U24 A;  4DGX A;  3CM3 A;  2B49 A;  5J8R A;  5KA1 A;  2Y2F A;  2SHP A;  3BRH A;  3QCG A;  4NWG A;  2B4O A;  3CWE A;  3F81 A;  1PYN A;  2H03 A;  3QCL A;  2OOQ A;  2VEV A;  3EMU A;  4NWF A;  2CM7 A;  2ZN7 A;  1YGU A;  4GE2 A;  2CNH A;  1WRM A;  1G7G A;  4NYH A;  2R0B A;  2H4K A;  1Q6N A;  1YZ4 A;  1ZZW A;  4NND A;  2HC2 A;  1XRI A;  5GTJ A;  1T49 A;  2NTA A;  2B07 A;  1C86 A;  2QDC A;  1PH0 A;  4WTY A;  2CM2 A;  3I7Z A;  5BZX A;  1WCH A;  1YTS A;  5KA7 A;  1L8K A;  1OEO X;  1MKP A;  1Q6J A;  4ERC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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