2QCJA

Native structure of lyp
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
284
structure length
280
Chain Sequence
LQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Lyp and its complex with a selective inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 64
structure length 280
sequence length 284
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2qcjA00
2VEWA 4GWFA 4GE2A 1FPRA 1PXHA 4RHGA 3QCFA 2QBQA 2I5XA 2H4KA 1NNYA 1ZZWA 1KAVA 3QCBA 2A3KA 4NNDA 2F6YA 4GE6A 2I4GA 3O4TA 1G1FA 2I3UA 2C7SA 1FPZA 3S3EA 2HVLA 1Q6NA 2M3VA 2I4EA 3AWFA 3V0GA 3QKQA 1WRMA 2HB1A 4JMKA 4OHEA 2P6XA 2F6TA 2QDCA 2VEYA 3O5XA 2QBPA 3I36A 1XRIA 2C46A 1OETA 1NL9A 2QEPA 4QUMA 4D3PA 4OHDA 1YTWA 4QUNA 3RZ2A 1G7FA 3D42A 4RH5A 5KA8A 4PVGA 1NWLA 3SR9A 4ZI4A 2F6FA 1QXKA 1T48A 4H1OA 3MOZA 2GWOA 2ZMMA 2DXPA 2J16B 3QCJA 3V0JA 1YTSA 4RKKA 2NLKA 3I80A 3QCNA 4D3RA 1XXVA 2H04A 3D1QA 1I9SA 4BJOA 3V0IA 2FH7A 2WGPA 4GFVA 3A5KA 4MBBA 3F99A 1A5YA 2I6JA 5BX1A 1OEMX 4J51A 4GFUA 2FJMA 3D9CA 4AZ1A 1YGRA 2BIJA 3RGOA 2CNHA 2J16A 3BRHA 1G4WR 2B4UA 2SHPA 3CM3A 2H4GA 2MBCA 3D44A 4NYHA 5BZXA 4NX8A 5BZZA 4WTYA 3QCEA 3S4OA 3LJ8A 3RO1A 2B07A 1M3GA 1PTUA 3ZMQA 1G4US 1ZC0A 1BZJA 1JF7A 2F6VA 2PT0A 5MMZB 2I6OA 4JMJA 4KYRA 2CNGA 2NT7A 1ZCLA 3QCDA 1T49A 1Q6JA 3S3FA 4BPCA 1ONZA 2PBNA 2HNPA 4QBWA 1BZHA 1YWFA 2CMBA 5KAAA 2CNIA 5KADA 4OHLA 3S4EA 1LQFA 2PI7A 1XXPA 1KAKA 2R0BA 2IMGA 2B4SA 2H03A 1YN9A 3S3HA 4GRYA 2J17A 1R6HA 5KA0A 3OLRA 5KA7A 1MKPA 1SUGA 3D1HA 4RI5A 3B7OA 2VEVA 2OOQA 4ERCA 1C88A 2A8BA 3ZM2A 1D5RA 3SMEA 2Y96A 1GWZA 2PQ5A 3PS5A 1I9TA 2AZRA 4WU3A 1PA9A 2I42A 2PSZA 4WOHA 2CM7A 1PTVA 4Y2EA 1Q6PA 2I6MA 1QZ0A 2ESBA 3AWEA 3D1OA 2F71A 1YFOA 1EEOA 1U25A 2CNEA 2BGDA 4D3QA 2G6ZA 1I57A 5IBMA 2VEUA 3MOWA 3GXHA 3QCCA 1YZ4A 1PYNA 4KYQA 1LARA 1NWEA 3O4UA 2JJDA 4GS0A 5BUGA 2I4HA 2I6IA 2OC3A 5AWXA 2QBRA 1G1GA 1PH0A 3EU0A 1YPTA 3N0AA 2CMCA 4RDDA 1Q6SA 1GFYA 2CMAA 3M4UA 3GXGA 4DGXA 4YR8B 5KACA 4GE5A 1YGUA 4S0GA 3EMUA 2QDPA 3V0FA 1ZCKA 3F41A 2B49A 1C84A 2HC2A 3A5JA 4Z6BA 5M43A 1BZCA 1YTNA 1RPMA 3S3KA 3NMEA 1XBOA 1C83A 3I7ZA 2NTAA 1PTYA 3QCIA 4ZRTA 5LXQB 2I6PA 1J4XA 4R30A 1V3AA 4R0SA 1Q6TA 2QCJA 2Q05A 5K22A 1PA1A 5K9VA 3QCHA 3F9BA 2QCTA 4R0TA 4QAHA 5KA2A 1C87A 3MMJA 4QBEA 2CM8A 2CNFA 3QCKA 1PTTA 2B4OA 2VEXA 1ONYA 1Q6MA 2BGEA 1OESA 2ZN7A 5K9WA 3OMHA 4OHIA 4PYHA 2HNQA 1WAXA 3QCGA 4IKCA 2NV5A 5K23A 3BLTA 1NO6A 1EENA 2F70A 3F9AA 1OHCA 2HXPA 5KA9A 4Y14A 2NZ6A 4NWGA 2F6WA 2B4PA 3EB1A 4QAPA 2E0TA 4ZN5A 5EHRA 3V0EA 1L8GA 1OEOX 2F6ZA 4HJQA 3ZM0A 2CFVA 4RI4A 2H02A 2I75A 3QCMA 3F81A 4JNBA 1OEVA 5IBSA 5KA4A 2HY3A 2OZ5A 1X24A 5EHPA 2CM3A 1U24A 2H4VA 5I6VA 2HC1A 1C86A 2GP0A 3V0HA 4H34A 2Q47A 2I1YA 3ZM1A 1RXDA 2BZLA 2YDUA 1OHEA 1AAXA 3O4SA 2QDMA 5J8RA 3EZZA 5KA3A 2OUDA 3H2XA 2BV5A 1VHRA 4JBCA 5GTJA 4DGPA 5KA1A 5K25A 1C85A 1FQ1A 3BLUA 4HJPA 3ZV2A 3U96A 3BM8A 1Q1MA 1OHDA 2FJNA 2F46A 5K24A 5KABA 4YAAA 2CJZA 5HDEA 1OEUA 3ZMPA 4TVVA 2Y2FA 3QCLA 1T4JA 2QBSA 4WU2A 2PA5A 1ECVA 3CWEA 1G1HA 2CM2A 4RH9A 1LYVA 4NWFA 3RGQA 1P15A 4KI9A 1JLNA 2G59A 4GRZA 1WCHA 2B3OA 3ZM3A 4ICZA 2RF6A 3O3LA 4I8NA 3AWGA 1G7GA 4HRFA 2I3RA 3QKPA 2P4DA 4OHHA 2NT2A 3EAXA 1U26A 2GJTA 2HCMA 1XM2A 2AHSA 4B04A 1NZ7A 3V0DA 1L8KA
chains in the Genus database with same CATH superfamily
3QCZA 4CVMA 2VEWA 4GWFA 4GE2A 1FPRA 5A5EA 1PXHA 4RHGA 2VTDA 3QCFA 2UAGA 4HV4A 2QBQA 2I5XA 2H4KA 1NNYA 1ZZWA 2AM2A 1KAVA 3QCBA 2A3KA 4NNDA 2F6YA 4GE6A 2I4GA 3O4TA 1G1FA 2I3UA 1UAGA 2C7SA 1FPZA 3S3EA 2HVLA 1Q6NA 2M3VA 2I4EA 3AWFA 3V0GA 3QKQA 1WRMA 2HB1A 4JMKA 4OHEA 2P6XA 2F6TA 2QDCA 2VEYA 3O5XA 2QBPA 3I36A 1XRIA 2C46A 3N2AA 1OETA 1NL9A 3MVNA 2QEPA 1GG4A 4QUMA 4D3PA 4OHDA 1YTWA 4QUNA 3RZ2A 1G7FA 3D42A 4RH5A 5KA8A 4PVGA 1NWLA 3SR9A 2JFHA 4ZI4A 2F6FA 1O5ZA 1QXKA 5A5FA 1T48A 4H1OA 3MOZA 2GWOA 2ZMMA 2DXPA 2JFFA 2J16B 3QCJA 3V0JA 1YTSA 4RKKA 2NLKA 3I80A 2AM1A 3QCNA 3LK7A 4D3RA 1XXVA 2H04A 3D1QA 1I9SA 4BJOA 1E8CA 1GQQA 3V0IA 2FH7A 2JFGA 2WGPA 4GFVA 3A5KA 4MBBA 3F99A 1JBWA 1A5YA 2I6JA 2XJAA 5BX1A 1OEMX 4J51A 4GFUA 2FJMA 3D9CA 4AZ1A 1YGRA 2BIJA 3RGOA 2CNHA 2J16A 3BRHA 1G4WR 2B4UA 2SHPA 3CM3A 2H4GA 2MBCA 3D44A 4NYHA 5BZXA 4NX8A 5BZZA 4WTYA 3QCEA 3S4OA 3LJ8A 3RO1A 2B07A 1M3GA 1PTUA 3ZMQA 1G4US 1ZC0A 1BZJA 1JF7A 1W7KA 2F6VA 2PT0A 5MMZB 2I6OA 1P3DA 4JMJA 4KYRA 3HN7A 2CNGA 2NT7A 1ZCLA 3QCDA 1T49A 1Q6JA 3S3FA 4BPCA 2Y66A 1ONZA 2PBNA 2HNPA 4QBWA 1BZHA 1YWFA 2CMBA 5KAAA 4QF5A 2CNIA 5KADA 3ZM6A 4OHLA 3S4EA 1LQFA 2PI7A 4CVLA 1XXPA 2GCBA 1KAKA 2R0BA 2IMGA 2B4SA 2H03A 1YN9A 3S3HA 4GRYA 2J17A 1R6HA 5KA0A 3OLRA 5KA7A 1MKPA 1SUGA 2WTZA 3D1HA 4RI5A 3B7OA 2VEVA 2OOQA 4ERCA 1C88A 2A8BA 3ZM2A 1D5RA 1E0DA 3SMEA 2Y96A 1GWZA 2PQ5A 1I9TA 2AZRA 3PS5A 4WU3A 1PA9A 2I42A 2PSZA 4WOHA 2CM7A 1PTVA 4Y2EA 1Q6PA 2I6MA 1QZ0A 2ESBA 3AWEA 3D1OA 2F71A 1YFOA 1EEOA 1U25A 2CNEA 2BGDA 4D3QA 2G6ZA 1I57A 3NRSA 5IBMA 2VEUA 3MOWA 3ZL8A 2GCAA 3GXHA 3QCCA 1YZ4A 1PYNA 4KYQA 1LARA 1NWEA 3O4UA 2JJDA 4GS0A 5BUGA 2VTEA 2I4HA 2I6IA 2OC3A 5AWXA 2QBRA 1G1GA 1PH0A 3EU0A 1YPTA 3N0AA 2CMCA 4RDDA 1Q6SA 1GFYA 2CMAA 3M4UA 3GXGA 4DGXA 4YR8B 5KACA 2X5OA 4GE5A 1YGUA 4S0GA 3EMUA 2QDPA 3V0FA 1ZCKA 3F41A 2B49A 1C84A 2HC2A 3A5JA 4Z6BA 5M43A 1BZCA 1YTNA 1RPMA 3S3KA 3NMEA 1XBOA 1C83A 3I7ZA 2Y67A 1W78A 2NTAA 1PTYA 3QCIA 2WJPA 4ZRTA 5LXQB 2I6PA 1J4XA 4R30A 1J6UA 1V3AA 4R0SA 1Q6TA 2QCJA 2Q05A 5K22A 1PA1A 2UUPA 5K9VA 3QCHA 4BUCA 4BUBA 1GQYA 3F9BA 2QCTA 4R0TA 4QAHA 2Y68A 5KA2A 1C87A 3MMJA 4QBEA 2CM8A 2CNFA 3QCKA 1PTTA 2B4OA 2VEXA 1ONYA 1Q6MA 2BGEA 1OESA 2ZN7A 5K9WA 3OMHA 4OHIA 4PYHA 2HNQA 1WAXA 3QCGA 4IKCA 2NV5A 5K23A 3BLTA 1NO6A 4C12A 1EENA 2F70A 1EEHA 3F9AA 1OHCA 2HXPA 5KA9A 4Y14A 2NZ6A 4NWGA 2F6WA 2B4PA 3EB1A 4UAGA 4QAPA 2E0TA 4ZN5A 3PYZA 5EHRA 3V0EA 1L8GA 1OEOX 2F6ZA 4HJQA 3ZM0A 2CFVA 4RI4A 2H02A 2I75A 3QCMA 3F81A 4JNBA 1OEVA 5IBSA 5KA4A 2HY3A 2OZ5A 1X24A 5EHPA 2CM3A 1U24A 2H4VA 2UUOA 5I6VA 2HC1A 1C86A 2GP0A 3V0HA 4H34A 2Q47A 2I1YA 3ZM1A 1RXDA 2BZLA 2YDUA 1OHEA 2VORA 1AAXA 3O4SA 2QDMA 5J8RA 3EZZA 5KA3A 1JBVA 4QDIA 2OUDA 3H2XA 2BV5A 1VHRA 4JBCA 2GC6A 5GTJA 4DGPA 5KA1A 5K25A 1C85A 1FQ1A 3BLUA 4HJPA 3ZV2A 3U96A 3BM8A 1Q1MA 1OHDA 2FJNA 2F46A 1P31A 5K24A 4ZIYA 5KABA 4YAAA 2CJZA 5HDEA 1OEUA 3ZMPA 2GC5A 4TVVA 2Y2FA 3QCLA 1T4JA 2QBSA 3UAGA 4WU2A 2PA5A 1ECVA 3CWEA 1G1HA 2CM2A 2F00A 4RH9A 1LYVA 4NWFA 3RGQA 1P15A 4KI9A 1JLNA 2G59A 4GRZA 3ZM5A 2VOSA 1WCHA 2B3OA 3ZM3A 4ICZA 2XPCA 2RF6A 3O3LA 4I8NA 3AWGA 1G7GA 4HRFA 4CVKA 2I3RA 3QKPA 2P4DA 4OHHA 2NT2A 2Y1OA 3EAXA 1U26A 2GJTA 2HCMA 1FGSA 1XM2A 2AHSA 4B04A 4C13A 1NZ7A 3V0DA 1L8KA
chains in the Genus database with same CATH topology
2VEWA 4GWFA 4GE2A 1FPRA 1PXHA 4RHGA 3QCFA 2QBQA 2I5XA 2H4KA 1NNYA 1ZZWA 1KAVA 3QCBA 2A3KA 4NNDA 2F6YA 4GE6A 2I4GA 3O4TA 1G1FA 2I3UA 2C7SA 1FPZA 3S3EA 2HVLA 1Q6NA 2M3VA 2I4EA 3AWFA 3V0GA 3QKQA 1WRMA 2HB1A 4JMKA 4OHEA 2P6XA 2F6TA 2QDCA 2VEYA 3O5XA 2QBPA 3I36A 1XRIA 2C46A 1OETA 1NL9A 2QEPA 4QUMA 4D3PA 4OHDA 1YTWA 4QUNA 3RZ2A 1G7FA 3D42A 4RH5A 5KA8A 4PVGA 1NWLA 3SR9A 4ZI4A 2F6FA 1QXKA 1T48A 4H1OA 3MOZA 2GWOA 2ZMMA 2DXPA 2J16B 3QCJA 3V0JA 1YTSA 4RKKA 2NLKA 3I80A 3QCNA 4D3RA 1XXVA 2H04A 3D1QA 1I9SA 4BJOA 3V0IA 2FH7A 2WGPA 4GFVA 3A5KA 4MBBA 3F99A 1A5YA 2I6JA 5BX1A 1OEMX 4J51A 4GFUA 2FJMA 3D9CA 4AZ1A 1YGRA 2BIJA 3RGOA 2CNHA 2J16A 3BRHA 1G4WR 2B4UA 2SHPA 3CM3A 2H4GA 2MBCA 3D44A 4NYHA 5BZXA 4NX8A 5BZZA 4WTYA 3QCEA 3S4OA 3LJ8A 3RO1A 2B07A 1M3GA 1PTUA 3ZMQA 1G4US 1ZC0A 1BZJA 1JF7A 2F6VA 2PT0A 5MMZB 2I6OA 4JMJA 4KYRA 2CNGA 2NT7A 1ZCLA 3QCDA 1T49A 1Q6JA 3S3FA 4BPCA 1ONZA 2PBNA 2HNPA 4QBWA 1BZHA 1YWFA 2CMBA 5KAAA 2CNIA 5KADA 4OHLA 3S4EA 1LQFA 2PI7A 1XXPA 1KAKA 2R0BA 2IMGA 2B4SA 2H03A 1YN9A 3S3HA 4GRYA 2J17A 1R6HA 5KA0A 3OLRA 5KA7A 1MKPA 1SUGA 3D1HA 4RI5A 3B7OA 2VEVA 2OOQA 4ERCA 1C88A 2A8BA 3ZM2A 1D5RA 3SMEA 2Y96A 1GWZA 2PQ5A 3PS5A 1I9TA 2AZRA 4WU3A 1PA9A 2I42A 2PSZA 4WOHA 2CM7A 1PTVA 4Y2EA 1Q6PA 2I6MA 1QZ0A 2ESBA 3AWEA 3D1OA 2F71A 1YFOA 1EEOA 1U25A 2CNEA 2BGDA 4D3QA 2G6ZA 1I57A 5IBMA 2VEUA 3MOWA 3GXHA 3QCCA 1YZ4A 1PYNA 4KYQA 1LARA 1NWEA 3O4UA 2JJDA 4GS0A 5BUGA 2I4HA 2I6IA 2OC3A 5AWXA 2QBRA 1G1GA 1PH0A 3EU0A 1YPTA 3N0AA 2CMCA 4RDDA 1Q6SA 1GFYA 2CMAA 3M4UA 3GXGA 4DGXA 4YR8B 5KACA 4GE5A 1YGUA 4S0GA 3EMUA 2QDPA 3V0FA 1ZCKA 3F41A 2B49A 1C84A 2HC2A 3A5JA 4Z6BA 5M43A 1BZCA 1YTNA 1RPMA 3S3KA 3NMEA 1XBOA 1C83A 3I7ZA 2NTAA 1PTYA 3QCIA 4ZRTA 5LXQB 2I6PA 1J4XA 4R30A 1V3AA 4R0SA 1Q6TA 2QCJA 2Q05A 5K22A 1PA1A 5K9VA 3QCHA 3F9BA 2QCTA 4R0TA 4QAHA 5KA2A 1C87A 3MMJA 4QBEA 2CM8A 2CNFA 3QCKA 1PTTA 2B4OA 2VEXA 1ONYA 1Q6MA 2BGEA 1OESA 2ZN7A 5K9WA 3OMHA 4OHIA 4PYHA 2HNQA 1WAXA 3QCGA 4IKCA 2NV5A 5K23A 3BLTA 1NO6A 1EENA 2F70A 3F9AA 1OHCA 2HXPA 5KA9A 4Y14A 2NZ6A 4NWGA 2F6WA 2B4PA 3EB1A 4QAPA 2E0TA 4ZN5A 5EHRA 3V0EA 1L8GA 1OEOX 2F6ZA 4HJQA 3ZM0A 2CFVA 4RI4A 2H02A 2I75A 3QCMA 3F81A 4JNBA 1OEVA 5IBSA 5KA4A 2HY3A 2OZ5A 1X24A 5EHPA 2CM3A 1U24A 2H4VA 5I6VA 2HC1A 1C86A 2GP0A 3V0HA 4H34A 2Q47A 2I1YA 3ZM1A 1RXDA 2BZLA 2YDUA 1OHEA 1AAXA 3O4SA 2QDMA 5J8RA 3EZZA 5KA3A 2OUDA 3H2XA 2BV5A 1VHRA 4JBCA 5GTJA 4DGPA 5KA1A 5K25A 1C85A 1FQ1A 3BLUA 4HJPA 3ZV2A 3U96A 3BM8A 1Q1MA 1OHDA 2FJNA 2F46A 5K24A 5KABA 4YAAA 2CJZA 5HDEA 1OEUA 3ZMPA 4TVVA 2Y2FA 3QCLA 1T4JA 2QBSA 4WU2A 2PA5A 1ECVA 3CWEA 1G1HA 2CM2A 4RH9A 1LYVA 4NWFA 3RGQA 1P15A 4KI9A 1JLNA 2G59A 4GRZA 1WCHA 2B3OA 3ZM3A 4ICZA 2RF6A 3O3LA 4I8NA 3AWGA 1G7GA 4HRFA 2I3RA 3QKPA 2P4DA 4OHHA 2NT2A 3EAXA 1U26A 2GJTA 2HCMA 1XM2A 2AHSA 4B04A 1NZ7A 3V0DA 1L8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VEW A;  4GWF A;  4GE2 A;  1FPR A;  1PXH A;  4RHG A;  3QCF A;  2QBQ A;  2I5X A;  2H4K A;  1NNY A;  1ZZW A;  1KAV A;  3QCB A;  2A3K A;  4NND A;  2F6Y A;  4GE6 A;  2I4G A;  3O4T A;  1G1F A;  2I3U A;  2C7S A;  1FPZ A;  3S3E A;  2HVL A;  1Q6N A;  2M3V A;  2I4E A;  3AWF A;  3V0G A;  3QKQ A;  1WRM A;  2HB1 A;  4JMK A;  4OHE A;  2P6X A;  2F6T A;  2QDC A;  2VEY A;  3O5X A;  2QBP A;  3I36 A;  1XRI A;  2C46 A;  1OET A;  1NL9 A;  2QEP A;  4QUM A;  4D3P A;  4OHD A;  1YTW A;  4QUN A;  3RZ2 A;  1G7F A;  3D42 A;  4RH5 A;  5KA8 A;  4PVG A;  1NWL A;  3SR9 A;  4ZI4 A;  2F6F A;  1QXK A;  1T48 A;  4H1O A;  3MOZ A;  2GWO A;  2ZMM A;  2DXP A;  2J16 B;  3QCJ A;  3V0J A;  1YTS A;  4RKK A;  2NLK A;  3I80 A;  3QCN A;  4D3R A;  1XXV A;  2H04 A;  3D1Q A;  1I9S A;  4BJO A;  3V0I A;  2FH7 A;  2WGP A;  4GFV A;  3A5K A;  4MBB A;  3F99 A;  1A5Y A;  2I6J A;  5BX1 A;  1OEM X;  4J51 A;  4GFU A;  2FJM A;  3D9C A;  4AZ1 A;  1YGR A;  2BIJ A;  3RGO A;  2CNH A;  2J16 A;  3BRH A;  1G4W R;  2B4U A;  2SHP A;  3CM3 A;  2H4G A;  2MBC A;  3D44 A;  4NYH A;  5BZX A;  4NX8 A;  5BZZ A;  4WTY A;  3QCE A;  3S4O A;  3LJ8 A;  3RO1 A;  2B07 A;  1M3G A;  1PTU A;  3ZMQ A;  1G4U S;  1ZC0 A;  1BZJ A;  1JF7 A;  2F6V A;  2PT0 A;  5MMZ B;  2I6O A;  4JMJ A;  4KYR A;  2CNG A;  2NT7 A;  1ZCL A;  3QCD A;  1T49 A;  1Q6J A;  3S3F A;  4BPC A;  1ONZ A;  2PBN A;  2HNP A;  4QBW A;  1BZH A;  1YWF A;  2CMB A;  5KAA A;  2CNI A;  5KAD A;  4OHL A;  3S4E A;  1LQF A;  2PI7 A;  1XXP A;  1KAK A;  2R0B A;  2IMG A;  2B4S A;  2H03 A;  1YN9 A;  3S3H A;  4GRY A;  2J17 A;  1R6H A;  5KA0 A;  3OLR A;  5KA7 A;  1MKP A;  1SUG A;  3D1H A;  4RI5 A;  3B7O A;  2VEV A;  2OOQ A;  4ERC A;  1C88 A;  2A8B A;  3ZM2 A;  1D5R A;  3SME A;  2Y96 A;  1GWZ A;  2PQ5 A;  3PS5 A;  1I9T A;  2AZR A;  4WU3 A;  1PA9 A;  2I42 A;  2PSZ A;  4WOH A;  2CM7 A;  1PTV A;  4Y2E A;  1Q6P A;  2I6M A;  1QZ0 A;  2ESB A;  3AWE A;  3D1O A;  2F71 A;  1YFO A;  1EEO A;  1U25 A;  2CNE A;  2BGD A;  4D3Q A;  2G6Z A;  1I57 A;  5IBM A;  2VEU A;  3MOW A;  3GXH A;  3QCC A;  1YZ4 A;  1PYN A;  4KYQ A;  1LAR A;  1NWE A;  3O4U A;  2JJD A;  4GS0 A;  5BUG A;  2I4H A;  2I6I A;  2OC3 A;  5AWX A;  2QBR A;  1G1G A;  1PH0 A;  3EU0 A;  1YPT A;  3N0A A;  2CMC A;  4RDD A;  1Q6S A;  1GFY A;  2CMA A;  3M4U A;  3GXG A;  4DGX A;  4YR8 B;  5KAC A;  4GE5 A;  1YGU A;  4S0G A;  3EMU A;  2QDP A;  3V0F A;  1ZCK A;  3F41 A;  2B49 A;  1C84 A;  2HC2 A;  3A5J A;  4Z6B A;  5M43 A;  1BZC A;  1YTN A;  1RPM A;  3S3K A;  3NME A;  1XBO A;  1C83 A;  3I7Z A;  2NTA A;  1PTY A;  3QCI A;  4ZRT A;  5LXQ B;  2I6P A;  1J4X A;  4R30 A;  1V3A A;  4R0S A;  1Q6T A;  2QCJ A;  2Q05 A;  5K22 A;  1PA1 A;  5K9V A;  3QCH A;  3F9B A;  2QCT A;  4R0T A;  4QAH A;  5KA2 A;  1C87 A;  3MMJ A;  4QBE A;  2CM8 A;  2CNF A;  3QCK A;  1PTT A;  2B4O A;  2VEX A;  1ONY A;  1Q6M A;  2BGE A;  1OES A;  2ZN7 A;  5K9W A;  3OMH A;  4OHI A;  4PYH A;  2HNQ A;  1WAX A;  3QCG A;  4IKC A;  2NV5 A;  5K23 A;  3BLT A;  1NO6 A;  1EEN A;  2F70 A;  3F9A A;  1OHC A;  2HXP A;  5KA9 A;  4Y14 A;  2NZ6 A;  4NWG A;  2F6W A;  2B4P A;  3EB1 A;  4QAP A;  2E0T A;  4ZN5 A;  5EHR A;  3V0E A;  1L8G A;  1OEO X;  2F6Z A;  4HJQ A;  3ZM0 A;  2CFV A;  4RI4 A;  2H02 A;  2I75 A;  3QCM A;  3F81 A;  4JNB A;  1OEV A;  5IBS A;  5KA4 A;  2HY3 A;  2OZ5 A;  1X24 A;  5EHP A;  2CM3 A;  1U24 A;  2H4V A;  5I6V A;  2HC1 A;  1C86 A;  2GP0 A;  3V0H A;  4H34 A;  2Q47 A;  2I1Y A;  3ZM1 A;  1RXD A;  2BZL A;  2YDU A;  1OHE A;  1AAX A;  3O4S A;  2QDM A;  5J8R A;  3EZZ A;  5KA3 A;  2OUD A;  3H2X A;  2BV5 A;  1VHR A;  4JBC A;  5GTJ A;  4DGP A;  5KA1 A;  5K25 A;  1C85 A;  1FQ1 A;  3BLU A;  4HJP A;  3ZV2 A;  3U96 A;  3BM8 A;  1Q1M A;  1OHD A;  2FJN A;  2F46 A;  5K24 A;  5KAB A;  4YAA A;  2CJZ A;  5HDE A;  1OEU A;  3ZMP A;  4TVV A;  2Y2F A;  3QCL A;  1T4J A;  2QBS A;  4WU2 A;  2PA5 A;  1ECV A;  3CWE A;  1G1H A;  2CM2 A;  4RH9 A;  1LYV A;  4NWF A;  3RGQ A;  1P15 A;  4KI9 A;  1JLN A;  2G59 A;  4GRZ A;  1WCH A;  2B3O A;  3ZM3 A;  4ICZ A;  2RF6 A;  3O3L A;  4I8N A;  3AWG A;  1G7G A;  4HRF A;  2I3R A;  3QKP A;  2P4D A;  4OHH A;  2NT2 A;  3EAX A;  1U26 A;  2GJT A;  2HCM A;  1XM2 A;  2AHS A;  4B04 A;  1NZ7 A;  3V0D A;  1L8K A; 
#chains in the Genus database with same CATH topology
 3QCZ A;  4CVM A;  2VEW A;  4GWF A;  4GE2 A;  1FPR A;  5A5E A;  1PXH A;  4RHG A;  2VTD A;  3QCF A;  2UAG A;  4HV4 A;  2QBQ A;  2I5X A;  2H4K A;  1NNY A;  1ZZW A;  2AM2 A;  1KAV A;  3QCB A;  2A3K A;  4NND A;  2F6Y A;  4GE6 A;  2I4G A;  3O4T A;  1G1F A;  2I3U A;  1UAG A;  2C7S A;  1FPZ A;  3S3E A;  2HVL A;  1Q6N A;  2M3V A;  2I4E A;  3AWF A;  3V0G A;  3QKQ A;  1WRM A;  2HB1 A;  4JMK A;  4OHE A;  2P6X A;  2F6T A;  2QDC A;  2VEY A;  3O5X A;  2QBP A;  3I36 A;  1XRI A;  2C46 A;  3N2A A;  1OET A;  1NL9 A;  3MVN A;  2QEP A;  1GG4 A;  4QUM A;  4D3P A;  4OHD A;  1YTW A;  4QUN A;  3RZ2 A;  1G7F A;  3D42 A;  4RH5 A;  5KA8 A;  4PVG A;  1NWL A;  3SR9 A;  2JFH A;  4ZI4 A;  2F6F A;  1O5Z A;  1QXK A;  5A5F A;  1T48 A;  4H1O A;  3MOZ A;  2GWO A;  2ZMM A;  2DXP A;  2JFF A;  2J16 B;  3QCJ A;  3V0J A;  1YTS A;  4RKK A;  2NLK A;  3I80 A;  2AM1 A;  3QCN A;  3LK7 A;  4D3R A;  1XXV A;  2H04 A;  3D1Q A;  1I9S A;  4BJO A;  1E8C A;  1GQQ A;  3V0I A;  2FH7 A;  2JFG A;  2WGP A;  4GFV A;  3A5K A;  4MBB A;  3F99 A;  1JBW A;  1A5Y A;  2I6J A;  2XJA A;  5BX1 A;  1OEM X;  4J51 A;  4GFU A;  2FJM A;  3D9C A;  4AZ1 A;  1YGR A;  2BIJ A;  3RGO A;  2CNH A;  2J16 A;  3BRH A;  1G4W R;  2B4U A;  2SHP A;  3CM3 A;  2H4G A;  2MBC A;  3D44 A;  4NYH A;  5BZX A;  4NX8 A;  5BZZ A;  4WTY A;  3QCE A;  3S4O A;  3LJ8 A;  3RO1 A;  2B07 A;  1M3G A;  1PTU A;  3ZMQ A;  1G4U S;  1ZC0 A;  1BZJ A;  1JF7 A;  1W7K A;  2F6V A;  2PT0 A;  5MMZ B;  2I6O A;  1P3D A;  4JMJ A;  4KYR A;  3HN7 A;  2CNG A;  2NT7 A;  1ZCL A;  3QCD A;  1T49 A;  1Q6J A;  3S3F A;  4BPC A;  2Y66 A;  1ONZ A;  2PBN A;  2HNP A;  4QBW A;  1BZH A;  1YWF A;  2CMB A;  5KAA A;  4QF5 A;  2CNI A;  5KAD A;  3ZM6 A;  4OHL A;  3S4E A;  1LQF A;  2PI7 A;  4CVL A;  1XXP A;  2GCB A;  1KAK A;  2R0B A;  2IMG A;  2B4S A;  2H03 A;  1YN9 A;  3S3H A;  4GRY A;  2J17 A;  1R6H A;  5KA0 A;  3OLR A;  5KA7 A;  1MKP A;  1SUG A;  2WTZ A;  3D1H A;  4RI5 A;  3B7O A;  2VEV A;  2OOQ A;  4ERC A;  1C88 A;  2A8B A;  3ZM2 A;  1D5R A;  1E0D A;  3SME A;  2Y96 A;  1GWZ A;  2PQ5 A;  1I9T A;  2AZR A;  3PS5 A;  4WU3 A;  1PA9 A;  2I42 A;  2PSZ A;  4WOH A;  2CM7 A;  1PTV A;  4Y2E A;  1Q6P A;  2I6M A;  1QZ0 A;  2ESB A;  3AWE A;  3D1O A;  2F71 A;  1YFO A;  1EEO A;  1U25 A;  2CNE A;  2BGD A;  4D3Q A;  2G6Z A;  1I57 A;  3NRS A;  5IBM A;  2VEU A;  3MOW A;  3ZL8 A;  2GCA A;  3GXH A;  3QCC A;  1YZ4 A;  1PYN A;  4KYQ A;  1LAR A;  1NWE A;  3O4U A;  2JJD A;  4GS0 A;  5BUG A;  2VTE A;  2I4H A;  2I6I A;  2OC3 A;  5AWX A;  2QBR A;  1G1G A;  1PH0 A;  3EU0 A;  1YPT A;  3N0A A;  2CMC A;  4RDD A;  1Q6S A;  1GFY A;  2CMA A;  3M4U A;  3GXG A;  4DGX A;  4YR8 B;  5KAC A;  2X5O A;  4GE5 A;  1YGU A;  4S0G A;  3EMU A;  2QDP A;  3V0F A;  1ZCK A;  3F41 A;  2B49 A;  1C84 A;  2HC2 A;  3A5J A;  4Z6B A;  5M43 A;  1BZC A;  1YTN A;  1RPM A;  3S3K A;  3NME A;  1XBO A;  1C83 A;  3I7Z A;  2Y67 A;  1W78 A;  2NTA A;  1PTY A;  3QCI A;  2WJP A;  4ZRT A;  5LXQ B;  2I6P A;  1J4X A;  4R30 A;  1J6U A;  1V3A A;  4R0S A;  1Q6T A;  2QCJ A;  2Q05 A;  5K22 A;  1PA1 A;  2UUP A;  5K9V A;  3QCH A;  4BUC A;  4BUB A;  1GQY A;  3F9B A;  2QCT A;  4R0T A;  4QAH A;  2Y68 A;  5KA2 A;  1C87 A;  3MMJ A;  4QBE A;  2CM8 A;  2CNF A;  3QCK A;  1PTT A;  2B4O A;  2VEX A;  1ONY A;  1Q6M A;  2BGE A;  1OES A;  2ZN7 A;  5K9W A;  3OMH A;  4OHI A;  4PYH A;  2HNQ A;  1WAX A;  3QCG A;  4IKC A;  2NV5 A;  5K23 A;  3BLT A;  1NO6 A;  4C12 A;  1EEN A;  2F70 A;  1EEH A;  3F9A A;  1OHC A;  2HXP A;  5KA9 A;  4Y14 A;  2NZ6 A;  4NWG A;  2F6W A;  2B4P A;  3EB1 A;  4UAG A;  4QAP A;  2E0T A;  4ZN5 A;  3PYZ A;  5EHR A;  3V0E A;  1L8G A;  1OEO X;  2F6Z A;  4HJQ A;  3ZM0 A;  2CFV A;  4RI4 A;  2H02 A;  2I75 A;  3QCM A;  3F81 A;  4JNB A;  1OEV A;  5IBS A;  5KA4 A;  2HY3 A;  2OZ5 A;  1X24 A;  5EHP A;  2CM3 A;  1U24 A;  2H4V A;  2UUO A;  5I6V A;  2HC1 A;  1C86 A;  2GP0 A;  3V0H A;  4H34 A;  2Q47 A;  2I1Y A;  3ZM1 A;  1RXD A;  2BZL A;  2YDU A;  1OHE A;  2VOR A;  1AAX A;  3O4S A;  2QDM A;  5J8R A;  3EZZ A;  5KA3 A;  1JBV A;  4QDI A;  2OUD A;  3H2X A;  2BV5 A;  1VHR A;  4JBC A;  2GC6 A;  5GTJ A;  4DGP A;  5KA1 A;  5K25 A;  1C85 A;  1FQ1 A;  3BLU A;  4HJP A;  3ZV2 A;  3U96 A;  3BM8 A;  1Q1M A;  1OHD A;  2FJN A;  2F46 A;  1P31 A;  5K24 A;  4ZIY A;  5KAB A;  4YAA A;  2CJZ A;  5HDE A;  1OEU A;  3ZMP A;  2GC5 A;  4TVV A;  2Y2F A;  3QCL A;  1T4J A;  2QBS A;  3UAG A;  4WU2 A;  2PA5 A;  1ECV A;  3CWE A;  1G1H A;  2CM2 A;  2F00 A;  4RH9 A;  1LYV A;  4NWF A;  3RGQ A;  1P15 A;  4KI9 A;  1JLN A;  2G59 A;  4GRZ A;  3ZM5 A;  2VOS A;  1WCH A;  2B3O A;  3ZM3 A;  4ICZ A;  2XPC A;  2RF6 A;  3O3L A;  4I8N A;  3AWG A;  1G7G A;  4HRF A;  4CVK A;  2I3R A;  3QKP A;  2P4D A;  4OHH A;  2NT2 A;  2Y1O A;  3EAX A;  1U26 A;  2GJT A;  2HCM A;  1FGS A;  1XM2 A;  2AHS A;  4B04 A;  4C13 A;  1NZ7 A;  3V0D A;  1L8K A; 
#chains in the Genus database with same CATH homology
 2VEW A;  4GWF A;  4GE2 A;  1FPR A;  1PXH A;  4RHG A;  3QCF A;  2QBQ A;  2I5X A;  2H4K A;  1NNY A;  1ZZW A;  1KAV A;  3QCB A;  2A3K A;  4NND A;  2F6Y A;  4GE6 A;  2I4G A;  3O4T A;  1G1F A;  2I3U A;  2C7S A;  1FPZ A;  3S3E A;  2HVL A;  1Q6N A;  2M3V A;  2I4E A;  3AWF A;  3V0G A;  3QKQ A;  1WRM A;  2HB1 A;  4JMK A;  4OHE A;  2P6X A;  2F6T A;  2QDC A;  2VEY A;  3O5X A;  2QBP A;  3I36 A;  1XRI A;  2C46 A;  1OET A;  1NL9 A;  2QEP A;  4QUM A;  4D3P A;  4OHD A;  1YTW A;  4QUN A;  3RZ2 A;  1G7F A;  3D42 A;  4RH5 A;  5KA8 A;  4PVG A;  1NWL A;  3SR9 A;  4ZI4 A;  2F6F A;  1QXK A;  1T48 A;  4H1O A;  3MOZ A;  2GWO A;  2ZMM A;  2DXP A;  2J16 B;  3QCJ A;  3V0J A;  1YTS A;  4RKK A;  2NLK A;  3I80 A;  3QCN A;  4D3R A;  1XXV A;  2H04 A;  3D1Q A;  1I9S A;  4BJO A;  3V0I A;  2FH7 A;  2WGP A;  4GFV A;  3A5K A;  4MBB A;  3F99 A;  1A5Y A;  2I6J A;  5BX1 A;  1OEM X;  4J51 A;  4GFU A;  2FJM A;  3D9C A;  4AZ1 A;  1YGR A;  2BIJ A;  3RGO A;  2CNH A;  2J16 A;  3BRH A;  1G4W R;  2B4U A;  2SHP A;  3CM3 A;  2H4G A;  2MBC A;  3D44 A;  4NYH A;  5BZX A;  4NX8 A;  5BZZ A;  4WTY A;  3QCE A;  3S4O A;  3LJ8 A;  3RO1 A;  2B07 A;  1M3G A;  1PTU A;  3ZMQ A;  1G4U S;  1ZC0 A;  1BZJ A;  1JF7 A;  2F6V A;  2PT0 A;  5MMZ B;  2I6O A;  4JMJ A;  4KYR A;  2CNG A;  2NT7 A;  1ZCL A;  3QCD A;  1T49 A;  1Q6J A;  3S3F A;  4BPC A;  1ONZ A;  2PBN A;  2HNP A;  4QBW A;  1BZH A;  1YWF A;  2CMB A;  5KAA A;  2CNI A;  5KAD A;  4OHL A;  3S4E A;  1LQF A;  2PI7 A;  1XXP A;  1KAK A;  2R0B A;  2IMG A;  2B4S A;  2H03 A;  1YN9 A;  3S3H A;  4GRY A;  2J17 A;  1R6H A;  5KA0 A;  3OLR A;  5KA7 A;  1MKP A;  1SUG A;  3D1H A;  4RI5 A;  3B7O A;  2VEV A;  2OOQ A;  4ERC A;  1C88 A;  2A8B A;  3ZM2 A;  1D5R A;  3SME A;  2Y96 A;  1GWZ A;  2PQ5 A;  3PS5 A;  1I9T A;  2AZR A;  4WU3 A;  1PA9 A;  2I42 A;  2PSZ A;  4WOH A;  2CM7 A;  1PTV A;  4Y2E A;  1Q6P A;  2I6M A;  1QZ0 A;  2ESB A;  3AWE A;  3D1O A;  2F71 A;  1YFO A;  1EEO A;  1U25 A;  2CNE A;  2BGD A;  4D3Q A;  2G6Z A;  1I57 A;  5IBM A;  2VEU A;  3MOW A;  3GXH A;  3QCC A;  1YZ4 A;  1PYN A;  4KYQ A;  1LAR A;  1NWE A;  3O4U A;  2JJD A;  4GS0 A;  5BUG A;  2I4H A;  2I6I A;  2OC3 A;  5AWX A;  2QBR A;  1G1G A;  1PH0 A;  3EU0 A;  1YPT A;  3N0A A;  2CMC A;  4RDD A;  1Q6S A;  1GFY A;  2CMA A;  3M4U A;  3GXG A;  4DGX A;  4YR8 B;  5KAC A;  4GE5 A;  1YGU A;  4S0G A;  3EMU A;  2QDP A;  3V0F A;  1ZCK A;  3F41 A;  2B49 A;  1C84 A;  2HC2 A;  3A5J A;  4Z6B A;  5M43 A;  1BZC A;  1YTN A;  1RPM A;  3S3K A;  3NME A;  1XBO A;  1C83 A;  3I7Z A;  2NTA A;  1PTY A;  3QCI A;  4ZRT A;  5LXQ B;  2I6P A;  1J4X A;  4R30 A;  1V3A A;  4R0S A;  1Q6T A;  2QCJ A;  2Q05 A;  5K22 A;  1PA1 A;  5K9V A;  3QCH A;  3F9B A;  2QCT A;  4R0T A;  4QAH A;  5KA2 A;  1C87 A;  3MMJ A;  4QBE A;  2CM8 A;  2CNF A;  3QCK A;  1PTT A;  2B4O A;  2VEX A;  1ONY A;  1Q6M A;  2BGE A;  1OES A;  2ZN7 A;  5K9W A;  3OMH A;  4OHI A;  4PYH A;  2HNQ A;  1WAX A;  3QCG A;  4IKC A;  2NV5 A;  5K23 A;  3BLT A;  1NO6 A;  1EEN A;  2F70 A;  3F9A A;  1OHC A;  2HXP A;  5KA9 A;  4Y14 A;  2NZ6 A;  4NWG A;  2F6W A;  2B4P A;  3EB1 A;  4QAP A;  2E0T A;  4ZN5 A;  5EHR A;  3V0E A;  1L8G A;  1OEO X;  2F6Z A;  4HJQ A;  3ZM0 A;  2CFV A;  4RI4 A;  2H02 A;  2I75 A;  3QCM A;  3F81 A;  4JNB A;  1OEV A;  5IBS A;  5KA4 A;  2HY3 A;  2OZ5 A;  1X24 A;  5EHP A;  2CM3 A;  1U24 A;  2H4V A;  5I6V A;  2HC1 A;  1C86 A;  2GP0 A;  3V0H A;  4H34 A;  2Q47 A;  2I1Y A;  3ZM1 A;  1RXD A;  2BZL A;  2YDU A;  1OHE A;  1AAX A;  3O4S A;  2QDM A;  5J8R A;  3EZZ A;  5KA3 A;  2OUD A;  3H2X A;  2BV5 A;  1VHR A;  4JBC A;  5GTJ A;  4DGP A;  5KA1 A;  5K25 A;  1C85 A;  1FQ1 A;  3BLU A;  4HJP A;  3ZV2 A;  3U96 A;  3BM8 A;  1Q1M A;  1OHD A;  2FJN A;  2F46 A;  5K24 A;  5KAB A;  4YAA A;  2CJZ A;  5HDE A;  1OEU A;  3ZMP A;  4TVV A;  2Y2F A;  3QCL A;  1T4J A;  2QBS A;  4WU2 A;  2PA5 A;  1ECV A;  3CWE A;  1G1H A;  2CM2 A;  4RH9 A;  1LYV A;  4NWF A;  3RGQ A;  1P15 A;  4KI9 A;  1JLN A;  2G59 A;  4GRZ A;  1WCH A;  2B3O A;  3ZM3 A;  4ICZ A;  2RF6 A;  3O3L A;  4I8N A;  3AWG A;  1G7G A;  4HRF A;  2I3R A;  3QKP A;  2P4D A;  4OHH A;  2NT2 A;  3EAX A;  1U26 A;  2GJT A;  2HCM A;  1XM2 A;  2AHS A;  4B04 A;  1NZ7 A;  3V0D A;  1L8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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