2QCTA

Structure of lyp with inhibitor i-c11
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
292
structure length
282
Chain Sequence
QREILQKFLDEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Lyp and its complex with a selective inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 72
structure length 282
sequence length 292
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2qctA00
3F99A 2BZLA 3D1HA 3S3KA 1OHEA 4ZN5A 4NWFA 1NWLA 4OHHA 2M3VA 1YFOA 2CNHA 3O4TA 1GFYA 3QCKA 2F70A 2HC2A 4QBWA 1G4US 2BV5A 1YTWA 4GE2A 2NZ6A 1U25A 4JNBA 4R0SA 3V0IA 2G6ZA 4KI9A 4RI5A 1T49A 5BZZA 2I6PA 5MMZB 2C46A 2VEUA 4PYHA 2VEYA 5BZXA 2H02A 1M3GA 1EENA 5BUGA 3F41A 4GWFA 4D3PA 1C85A 2HC1A 4WOHA 1C84A 2JJDA 4GRYA 1I9TA 4HRFA 1PTVA 2I6MA 5KA0A 2ZN7A 3QCDA 4R0TA 1U24A 5M43A 5KA7A 4OHDA 4NYHA 1WAXA 1L8GA 3D1QA 3QCNA 3I7ZA 1I9SA 2J16B 2E0TA 1YN9A 3N0AA 3B7OA 1MKPA 2B4OA 5KA3A 4RH5A 4Z6BA 3V0EA 1OESA 3BLTA 4JMKA 4AZ1A 2VEVA 3O3LA 4DGXA 5KA1A 2PI7A 1D5RA 1ZCKA 4D3RA 4Y2EA 1ZCLA 3QCJA 1OEVA 2WGPA 3BRHA 3RZ2A 3A5JA 4WU3A 3ZV2A 2MBCA 3V0DA 1Q6JA 2R0BA 5K9VA 4Y14A 3BM8A 5HDEA 3AWGA 4ERCA 2Q47A 4YR8B 4H34A 2CM2A 4QUNA 2GJTA 5KA4A 2CFVA 2C7SA 2OZ5A 4NX8A 2H4KA 2I6IA 2ESBA 1FPRA 2Q05A 5AWXA 2HNQA 2CNIA 2QCJA 4I8NA 2CNFA 4BPCA 1X24A 4DGPA 4RDDA 2B4SA 1KAKA 3MMJA 4HJPA 2PBNA 3QCEA 4QBEA 1YTNA 3EAXA 1G1HA 2A8BA 4GS0A 1PTUA 4YAAA 2CMBA 3O5XA 1BZHA 2AZRA 2F71A 5KA9A 2QBQA 5KADA 4ZRTA 4QAPA 2AHSA 3CWEA 4GE5A 3EMUA 3QKQA 1C88A 1OETA 4OHLA 2CMCA 1YGUA 2H03A 1G7FA 1J4XA 3V0HA 2I6JA 5IBMA 3H2XA 1T4JA 2PT0A 2F6ZA 5K22A 2I4EA 1JF7A 2P6XA 1XXPA 4PVGA 1PH0A 1Q6TA 3OMHA 2J17A 3V0JA 2OC3A 1XRIA 1YGRA 1RPMA 1LYVA 3S3EA 2I3UA 2QBSA 5IBSA 1WRMA 4NWGA 3S4OA 2I6OA 3QCGA 3PS5A 3D44A 1Q6SA 2P4DA 3QKPA 2I4GA 1PTTA 2QBPA 3ZM2A 1FQ1A 4ICZA 1SUGA 3O4UA 4QAHA 2F6YA 4NNDA 3RGOA 3QCIA 2H4VA 3RO1A 1OEUA 4OHIA 3V0FA 4KYQA 1ZC0A 1KAVA 2I75A 4WTYA 1WCHA 1V3AA 4S0GA 2Y96A 2F6TA 1QXKA 2NTAA 4JMJA 2BGEA 2HNPA 3M4UA 1Q1MA 4GRZA 2BGDA 3AWEA 2CMAA 5KAAA 3MOZA 1C83A 1G1GA 2CJZA 3ZM0A 1VHRA 3D9CA 2I4HA 2QDPA 3A5KA 1L8KA 2SHPA 3SR9A 5GTJA 3GXGA 3S4EA 1T48A 2I42A 2B3OA 1I57A 3EZZA 1ZZWA 1G1FA 4GFUA 4RHGA 1NO6A 4JBCA 4BJOA 1OEOX 1U26A 3QCCA 2YDUA 4MBBA 1JLNA 1PYNA 2G59A 1XBOA 3SMEA 3QCMA 4J51A 2Y2FA 2NT7A 3I80A 2HB1A 4B04A 5KABA 1P15A 1ECVA 4R30A 2QDCA 5LXQB 2CM7A 3LJ8A 2DXPA 3GXHA 3QCFA 1PXHA 4IKCA 2PSZA 1QZ0A 1LQFA 3ZMPA 5K25A 2OUDA 1YTSA 3S3HA 1EEOA 1AAXA 5J8RA 3S3FA 2PQ5A 2A3KA 2GP0A 2VEWA 1GWZA 3CM3A 1BZCA 3F9BA 3EU0A 4QUMA 4GFVA 1PA9A 1PA1A 3MOWA 2NV5A 1NL9A 2FH7A 1G4WR 2OOQA 2HXPA 3ZM3A 5K9WA 1G7GA 3RGQA 2ZMMA 1OHDA 1OHCA 5EHPA 1A5YA 3QCHA 1Q6NA 2CNEA 2PA5A 5EHRA 2CM3A 5KA2A 3ZMQA 4HJQA 1C86A 5BX1A 2I3RA 1XXVA 2QBRA 1YWFA 4H1OA 3QCLA 3BLUA 3D1OA 2B49A 2QEPA 1NNYA 1PTYA 2BIJA 1NWEA 4TVVA 4WU2A 2CNGA 2B4PA 1YPTA 2QCTA 5KA8A 2FJNA 1Q6PA 1C87A 1ONYA 2GWOA 2IMGA 3U96A 5K23A 3AWFA 4RH9A 1LARA 2F46A 3OLRA 1NZ7A 4GE6A 3QCBA 1FPZA 5K24A 4D3QA 4RI4A 3NMEA 2J16A 3O4SA 3ZM1A 2B07A 4OHEA 2H04A 2F6FA 1ONZA 3EB1A 2HY3A 2HVLA 2F6VA 4KYRA 2QDMA 2H4GA 1YZ4A 4ZI4A 1XM2A 3V0GA 3F9AA 1BZJA 2HCMA 2CM8A 5KACA 2I1YA 3I36A 2NLKA 1RXDA 2RF6A 1Q6MA 4RKKA 2VEXA 3D42A 2I5XA 2B4UA 5I6VA 1R6HA 2F6WA 2NT2A 2FJMA 1OEMX 3F81A
chains in the Genus database with same CATH superfamily
3F99A 3N2AA 2BZLA 3D1HA 3S3KA 1OHEA 4ZN5A 4NWFA 1NWLA 4OHHA 2M3VA 1YFOA 2CNHA 3O4TA 1GFYA 3QCKA 1JBWA 2F70A 2HC2A 4QBWA 1G4US 2BV5A 1YTWA 4GE2A 2NZ6A 1U25A 2Y66A 4JNBA 4R0SA 3V0IA 2G6ZA 4KI9A 4RI5A 1T49A 5BZZA 2I6PA 5MMZB 2C46A 2VEUA 4PYHA 2VEYA 5BZXA 1P3DA 2H02A 1M3GA 1EENA 5BUGA 2VTDA 3F41A 4GWFA 1P31A 4D3PA 1C85A 2HC1A 4WOHA 1J6UA 4C13A 4C12A 1C84A 2JJDA 4GRYA 4QF5A 1I9TA 4HRFA 1PTVA 2I6MA 5KA0A 2AM1A 2ZN7A 3QCDA 4R0TA 1U24A 5M43A 5KA7A 4OHDA 4NYHA 1WAXA 1L8GA 3D1QA 3QCNA 3I7ZA 1EEHA 1I9SA 2GCBA 2J16B 2E0TA 1YN9A 3N0AA 3B7OA 1MKPA 2B4OA 5A5EA 2XJAA 5KA3A 4RH5A 4Z6BA 3V0EA 1OESA 3BLTA 4JMKA 4AZ1A 2VEVA 3O3LA 4DGXA 3HN7A 2PI7A 5KA1A 1D5RA 4BUCA 1ZCKA 4D3RA 4Y2EA 1ZCLA 2VORA 1OEVA 2WGPA 3BRHA 3QCJA 3RZ2A 3A5JA 4WU3A 3ZV2A 2MBCA 3V0DA 1Q6JA 2R0BA 5K9VA 4Y14A 3BM8A 5HDEA 3AWGA 4ERCA 2X5OA 2Q47A 4YR8B 4H34A 2CM2A 4QUNA 2GJTA 2AM2A 5KA4A 4QDIA 2CFVA 2C7SA 2OZ5A 4NX8A 2XPCA 2H4KA 2I6IA 2ESBA 1FPRA 2Q05A 5AWXA 2HNQA 3ZM5A 2CNIA 2QCJA 4I8NA 2CNFA 4BPCA 1X24A 4DGPA 4BUBA 4RDDA 2B4SA 1KAKA 3MMJA 4HJPA 2PBNA 3QCEA 4QBEA 1YTNA 3EAXA 1G1HA 2A8BA 4GS0A 1PTUA 4YAAA 2CMBA 3O5XA 4UAGA 3PYZA 1BZHA 2AZRA 2F71A 5KA9A 2QBQA 5KADA 4ZRTA 4QAPA 2AHSA 3CWEA 4GE5A 3EMUA 3QKQA 1C88A 1OETA 4OHLA 2CMCA 1YGUA 2H03A 1G7FA 1J4XA 3V0HA 2I6JA 5IBMA 1GQQA 3H2XA 1T4JA 2PT0A 2F6ZA 5K22A 2I4EA 1JF7A 2P6XA 1XXPA 4PVGA 1PH0A 1Q6TA 3OMHA 2J17A 3V0JA 2OC3A 1XRIA 1YGRA 1RPMA 1LYVA 3S3EA 2I3UA 2QBSA 2UUPA 2WJPA 5IBSA 1WRMA 4NWGA 3S4OA 2I6OA 3QCGA 3PS5A 3D44A 1W78A 1Q6SA 2P4DA 3QKPA 2I4GA 1PTTA 4CVLA 2QBPA 3ZM2A 1FQ1A 4ICZA 1SUGA 3O4UA 4QAHA 2F6YA 4NNDA 3RGOA 3QCIA 2H4VA 3RO1A 1OEUA 4OHIA 3V0FA 4KYQA 1ZC0A 5A5FA 1KAVA 2I75A 4WTYA 1WCHA 1V3AA 4S0GA 2Y96A 2F6TA 1QXKA 2NTAA 4JMJA 2BGEA 2HNPA 3M4UA 1Q1MA 3UAGA 4GRZA 2BGDA 2UAGA 3AWEA 4CVKA 2CMAA 5KAAA 3MOZA 1C83A 1G1GA 2CJZA 3ZM0A 1VHRA 3D9CA 2I4HA 2QDPA 2GC6A 3A5KA 1L8KA 2SHPA 3SR9A 5GTJA 3GXGA 3S4EA 1T48A 2I42A 2B3OA 1I57A 3EZZA 1ZZWA 1G1FA 4GFUA 4RHGA 1NO6A 4JBCA 4BJOA 4CVMA 1OEOX 1U26A 3QCCA 1W7KA 4ZIYA 2YDUA 4MBBA 1JLNA 1PYNA 2G59A 1XBOA 3SMEA 3QCMA 4J51A 2Y2FA 2NT7A 3I80A 2HB1A 4B04A 5KABA 1P15A 1ECVA 1E8CA 2Y1OA 4R30A 2QDCA 5LXQB 2CM7A 3LJ8A 2DXPA 3GXHA 2VOSA 3QCFA 3MVNA 1PXHA 4IKCA 2PSZA 1QZ0A 1LQFA 3ZMPA 5K25A 2F00A 2OUDA 1GQYA 1YTSA 3S3HA 1EEOA 1AAXA 5J8RA 3S3FA 2PQ5A 2UUOA 2A3KA 2GP0A 2VEWA 1GWZA 3CM3A 2GCAA 1FGSA 1BZCA 3F9BA 3EU0A 4QUMA 4GFVA 1PA9A 1PA1A 3MOWA 2NV5A 1NL9A 2FH7A 1G4WR 2OOQA 2JFFA 2HXPA 3ZM3A 5K9WA 1G7GA 3RGQA 2ZMMA 1OHDA 1OHCA 5EHPA 1A5YA 3NRSA 3QCHA 1Q6NA 2CNEA 2PA5A 5EHRA 2CM3A 5KA2A 3ZMQA 4HJQA 1O5ZA 1C86A 5BX1A 2I3RA 1XXVA 2QBRA 1YWFA 4H1OA 3QCLA 3BLUA 3D1OA 1UAGA 2B49A 2QEPA 1NNYA 1PTYA 2BIJA 1NWEA 2Y68A 4TVVA 4WU2A 2CNGA 2B4PA 1YPTA 2QCTA 5KA8A 2FJNA 3ZL8A 1Q6PA 1C87A 1ONYA 2GWOA 2IMGA 3U96A 5K23A 3AWFA 4RH9A 1LARA 2F46A 3OLRA 1NZ7A 4GE6A 3QCBA 1FPZA 5K24A 4D3QA 2WTZA 4RI4A 3NMEA 2JFHA 2J16A 3O4SA 1E0DA 3QCZA 2VTEA 3ZM1A 2B07A 4OHEA 2H04A 2F6FA 1ONZA 1GG4A 3EB1A 2HY3A 2HVLA 2F6VA 4KYRA 2QDMA 2H4GA 1YZ4A 4ZI4A 1XM2A 3V0GA 3F9AA 1BZJA 2HCMA 2CM8A 3LK7A 5KACA 2I1YA 3I36A 2NLKA 1RXDA 2RF6A 1Q6MA 4RKKA 2GC5A 3ZM6A 2VEXA 3D42A 2I5XA 2B4UA 4HV4A 5I6VA 1R6HA 2F6WA 2NT2A 2FJMA 1OEMX 2JFGA 1JBVA 3F81A 2Y67A
chains in the Genus database with same CATH topology
3F99A 2BZLA 3D1HA 3S3KA 1OHEA 4ZN5A 4NWFA 1NWLA 4OHHA 2M3VA 1YFOA 2CNHA 3O4TA 1GFYA 3QCKA 2F70A 2HC2A 4QBWA 1G4US 2BV5A 1YTWA 4GE2A 2NZ6A 1U25A 4JNBA 4R0SA 3V0IA 2G6ZA 4KI9A 4RI5A 1T49A 5BZZA 2I6PA 5MMZB 2C46A 2VEUA 4PYHA 2VEYA 5BZXA 2H02A 1M3GA 1EENA 5BUGA 3F41A 4GWFA 4D3PA 1C85A 2HC1A 4WOHA 1C84A 2JJDA 4GRYA 1I9TA 4HRFA 1PTVA 2I6MA 5KA0A 2ZN7A 3QCDA 4R0TA 1U24A 5M43A 5KA7A 4OHDA 4NYHA 1WAXA 1L8GA 3D1QA 3QCNA 3I7ZA 1I9SA 2J16B 2E0TA 1YN9A 3N0AA 3B7OA 1MKPA 2B4OA 5KA3A 4RH5A 4Z6BA 3V0EA 1OESA 3BLTA 4JMKA 4AZ1A 2VEVA 3O3LA 4DGXA 5KA1A 2PI7A 1D5RA 1ZCKA 4D3RA 4Y2EA 1ZCLA 3QCJA 1OEVA 2WGPA 3BRHA 3RZ2A 3A5JA 4WU3A 3ZV2A 2MBCA 3V0DA 1Q6JA 2R0BA 5K9VA 4Y14A 3BM8A 5HDEA 3AWGA 4ERCA 2Q47A 4YR8B 4H34A 2CM2A 4QUNA 2GJTA 5KA4A 2CFVA 2C7SA 2OZ5A 4NX8A 2H4KA 2I6IA 2ESBA 1FPRA 2Q05A 5AWXA 2HNQA 2CNIA 2QCJA 4I8NA 2CNFA 4BPCA 1X24A 4DGPA 4RDDA 2B4SA 1KAKA 3MMJA 4HJPA 2PBNA 3QCEA 4QBEA 1YTNA 3EAXA 1G1HA 2A8BA 4GS0A 1PTUA 4YAAA 2CMBA 3O5XA 1BZHA 2AZRA 2F71A 5KA9A 2QBQA 5KADA 4ZRTA 4QAPA 2AHSA 3CWEA 4GE5A 3EMUA 3QKQA 1C88A 1OETA 4OHLA 2CMCA 1YGUA 2H03A 1G7FA 1J4XA 3V0HA 2I6JA 5IBMA 3H2XA 1T4JA 2PT0A 2F6ZA 5K22A 2I4EA 1JF7A 2P6XA 1XXPA 4PVGA 1PH0A 1Q6TA 3OMHA 2J17A 3V0JA 2OC3A 1XRIA 1YGRA 1RPMA 1LYVA 3S3EA 2I3UA 2QBSA 5IBSA 1WRMA 4NWGA 3S4OA 2I6OA 3QCGA 3PS5A 3D44A 1Q6SA 2P4DA 3QKPA 2I4GA 1PTTA 2QBPA 3ZM2A 1FQ1A 4ICZA 1SUGA 3O4UA 4QAHA 2F6YA 4NNDA 3RGOA 3QCIA 2H4VA 3RO1A 1OEUA 4OHIA 3V0FA 4KYQA 1ZC0A 1KAVA 2I75A 4WTYA 1WCHA 1V3AA 4S0GA 2Y96A 2F6TA 1QXKA 2NTAA 4JMJA 2BGEA 2HNPA 3M4UA 1Q1MA 4GRZA 2BGDA 3AWEA 2CMAA 5KAAA 3MOZA 1C83A 1G1GA 2CJZA 3ZM0A 1VHRA 3D9CA 2I4HA 2QDPA 3A5KA 1L8KA 2SHPA 3SR9A 5GTJA 3GXGA 3S4EA 1T48A 2I42A 2B3OA 1I57A 3EZZA 1ZZWA 1G1FA 4GFUA 4RHGA 1NO6A 4JBCA 4BJOA 1OEOX 1U26A 3QCCA 2YDUA 4MBBA 1JLNA 1PYNA 2G59A 1XBOA 3SMEA 3QCMA 4J51A 2Y2FA 2NT7A 3I80A 2HB1A 4B04A 5KABA 1P15A 1ECVA 4R30A 2QDCA 5LXQB 2CM7A 3LJ8A 2DXPA 3GXHA 3QCFA 1PXHA 4IKCA 2PSZA 1QZ0A 1LQFA 3ZMPA 5K25A 2OUDA 1YTSA 3S3HA 1EEOA 1AAXA 5J8RA 3S3FA 2PQ5A 2A3KA 2GP0A 2VEWA 1GWZA 3CM3A 1BZCA 3F9BA 3EU0A 4QUMA 4GFVA 1PA9A 1PA1A 3MOWA 2NV5A 1NL9A 2FH7A 1G4WR 2OOQA 2HXPA 3ZM3A 5K9WA 1G7GA 3RGQA 2ZMMA 1OHDA 1OHCA 5EHPA 1A5YA 3QCHA 1Q6NA 2CNEA 2PA5A 5EHRA 2CM3A 5KA2A 3ZMQA 4HJQA 1C86A 5BX1A 2I3RA 1XXVA 2QBRA 1YWFA 4H1OA 3QCLA 3BLUA 3D1OA 2B49A 2QEPA 1NNYA 1PTYA 2BIJA 1NWEA 4TVVA 4WU2A 2CNGA 2B4PA 1YPTA 2QCTA 5KA8A 2FJNA 1Q6PA 1C87A 1ONYA 2GWOA 2IMGA 3U96A 5K23A 3AWFA 4RH9A 1LARA 2F46A 3OLRA 1NZ7A 4GE6A 3QCBA 1FPZA 5K24A 4D3QA 4RI4A 3NMEA 2J16A 3O4SA 3ZM1A 2B07A 4OHEA 2H04A 2F6FA 1ONZA 3EB1A 2HY3A 2HVLA 2F6VA 4KYRA 2QDMA 2H4GA 1YZ4A 4ZI4A 1XM2A 3V0GA 3F9AA 1BZJA 2HCMA 2CM8A 5KACA 2I1YA 3I36A 2NLKA 1RXDA 2RF6A 1Q6MA 4RKKA 2VEXA 3D42A 2I5XA 2B4UA 5I6VA 1R6HA 2F6WA 2NT2A 2FJMA 1OEMX 3F81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F99 A;  2BZL A;  3D1H A;  3S3K A;  1OHE A;  4ZN5 A;  4NWF A;  1NWL A;  4OHH A;  2M3V A;  1YFO A;  2CNH A;  3O4T A;  1GFY A;  3QCK A;  2F70 A;  2HC2 A;  4QBW A;  1G4U S;  2BV5 A;  1YTW A;  4GE2 A;  2NZ6 A;  1U25 A;  4JNB A;  4R0S A;  3V0I A;  2G6Z A;  4KI9 A;  4RI5 A;  1T49 A;  5BZZ A;  2I6P A;  5MMZ B;  2C46 A;  2VEU A;  4PYH A;  2VEY A;  5BZX A;  2H02 A;  1M3G A;  1EEN A;  5BUG A;  3F41 A;  4GWF A;  4D3P A;  1C85 A;  2HC1 A;  4WOH A;  1C84 A;  2JJD A;  4GRY A;  1I9T A;  4HRF A;  1PTV A;  2I6M A;  5KA0 A;  2ZN7 A;  3QCD A;  4R0T A;  1U24 A;  5M43 A;  5KA7 A;  4OHD A;  4NYH A;  1WAX A;  1L8G A;  3D1Q A;  3QCN A;  3I7Z A;  1I9S A;  2J16 B;  2E0T A;  1YN9 A;  3N0A A;  3B7O A;  1MKP A;  2B4O A;  5KA3 A;  4RH5 A;  4Z6B A;  3V0E A;  1OES A;  3BLT A;  4JMK A;  4AZ1 A;  2VEV A;  3O3L A;  4DGX A;  5KA1 A;  2PI7 A;  1D5R A;  1ZCK A;  4D3R A;  4Y2E A;  1ZCL A;  3QCJ A;  1OEV A;  2WGP A;  3BRH A;  3RZ2 A;  3A5J A;  4WU3 A;  3ZV2 A;  2MBC A;  3V0D A;  1Q6J A;  2R0B A;  5K9V A;  4Y14 A;  3BM8 A;  5HDE A;  3AWG A;  4ERC A;  2Q47 A;  4YR8 B;  4H34 A;  2CM2 A;  4QUN A;  2GJT A;  5KA4 A;  2CFV A;  2C7S A;  2OZ5 A;  4NX8 A;  2H4K A;  2I6I A;  2ESB A;  1FPR A;  2Q05 A;  5AWX A;  2HNQ A;  2CNI A;  2QCJ A;  4I8N A;  2CNF A;  4BPC A;  1X24 A;  4DGP A;  4RDD A;  2B4S A;  1KAK A;  3MMJ A;  4HJP A;  2PBN A;  3QCE A;  4QBE A;  1YTN A;  3EAX A;  1G1H A;  2A8B A;  4GS0 A;  1PTU A;  4YAA A;  2CMB A;  3O5X A;  1BZH A;  2AZR A;  2F71 A;  5KA9 A;  2QBQ A;  5KAD A;  4ZRT A;  4QAP A;  2AHS A;  3CWE A;  4GE5 A;  3EMU A;  3QKQ A;  1C88 A;  1OET A;  4OHL A;  2CMC A;  1YGU A;  2H03 A;  1G7F A;  1J4X A;  3V0H A;  2I6J A;  5IBM A;  3H2X A;  1T4J A;  2PT0 A;  2F6Z A;  5K22 A;  2I4E A;  1JF7 A;  2P6X A;  1XXP A;  4PVG A;  1PH0 A;  1Q6T A;  3OMH A;  2J17 A;  3V0J A;  2OC3 A;  1XRI A;  1YGR A;  1RPM A;  1LYV A;  3S3E A;  2I3U A;  2QBS A;  5IBS A;  1WRM A;  4NWG A;  3S4O A;  2I6O A;  3QCG A;  3PS5 A;  3D44 A;  1Q6S A;  2P4D A;  3QKP A;  2I4G A;  1PTT A;  2QBP A;  3ZM2 A;  1FQ1 A;  4ICZ A;  1SUG A;  3O4U A;  4QAH A;  2F6Y A;  4NND A;  3RGO A;  3QCI A;  2H4V A;  3RO1 A;  1OEU A;  4OHI A;  3V0F A;  4KYQ A;  1ZC0 A;  1KAV A;  2I75 A;  4WTY A;  1WCH A;  1V3A A;  4S0G A;  2Y96 A;  2F6T A;  1QXK A;  2NTA A;  4JMJ A;  2BGE A;  2HNP A;  3M4U A;  1Q1M A;  4GRZ A;  2BGD A;  3AWE A;  2CMA A;  5KAA A;  3MOZ A;  1C83 A;  1G1G A;  2CJZ A;  3ZM0 A;  1VHR A;  3D9C A;  2I4H A;  2QDP A;  3A5K A;  1L8K A;  2SHP A;  3SR9 A;  5GTJ A;  3GXG A;  3S4E A;  1T48 A;  2I42 A;  2B3O A;  1I57 A;  3EZZ A;  1ZZW A;  1G1F A;  4GFU A;  4RHG A;  1NO6 A;  4JBC A;  4BJO A;  1OEO X;  1U26 A;  3QCC A;  2YDU A;  4MBB A;  1JLN A;  1PYN A;  2G59 A;  1XBO A;  3SME A;  3QCM A;  4J51 A;  2Y2F A;  2NT7 A;  3I80 A;  2HB1 A;  4B04 A;  5KAB A;  1P15 A;  1ECV A;  4R30 A;  2QDC A;  5LXQ B;  2CM7 A;  3LJ8 A;  2DXP A;  3GXH A;  3QCF A;  1PXH A;  4IKC A;  2PSZ A;  1QZ0 A;  1LQF A;  3ZMP A;  5K25 A;  2OUD A;  1YTS A;  3S3H A;  1EEO A;  1AAX A;  5J8R A;  3S3F A;  2PQ5 A;  2A3K A;  2GP0 A;  2VEW A;  1GWZ A;  3CM3 A;  1BZC A;  3F9B A;  3EU0 A;  4QUM A;  4GFV A;  1PA9 A;  1PA1 A;  3MOW A;  2NV5 A;  1NL9 A;  2FH7 A;  1G4W R;  2OOQ A;  2HXP A;  3ZM3 A;  5K9W A;  1G7G A;  3RGQ A;  2ZMM A;  1OHD A;  1OHC A;  5EHP A;  1A5Y A;  3QCH A;  1Q6N A;  2CNE A;  2PA5 A;  5EHR A;  2CM3 A;  5KA2 A;  3ZMQ A;  4HJQ A;  1C86 A;  5BX1 A;  2I3R A;  1XXV A;  2QBR A;  1YWF A;  4H1O A;  3QCL A;  3BLU A;  3D1O A;  2B49 A;  2QEP A;  1NNY A;  1PTY A;  2BIJ A;  1NWE A;  4TVV A;  4WU2 A;  2CNG A;  2B4P A;  1YPT A;  2QCT A;  5KA8 A;  2FJN A;  1Q6P A;  1C87 A;  1ONY A;  2GWO A;  2IMG A;  3U96 A;  5K23 A;  3AWF A;  4RH9 A;  1LAR A;  2F46 A;  3OLR A;  1NZ7 A;  4GE6 A;  3QCB A;  1FPZ A;  5K24 A;  4D3Q A;  4RI4 A;  3NME A;  2J16 A;  3O4S A;  3ZM1 A;  2B07 A;  4OHE A;  2H04 A;  2F6F A;  1ONZ A;  3EB1 A;  2HY3 A;  2HVL A;  2F6V A;  4KYR A;  2QDM A;  2H4G A;  1YZ4 A;  4ZI4 A;  1XM2 A;  3V0G A;  3F9A A;  1BZJ A;  2HCM A;  2CM8 A;  5KAC A;  2I1Y A;  3I36 A;  2NLK A;  1RXD A;  2RF6 A;  1Q6M A;  4RKK A;  2VEX A;  3D42 A;  2I5X A;  2B4U A;  5I6V A;  1R6H A;  2F6W A;  2NT2 A;  2FJM A;  1OEM X;  3F81 A; 
#chains in the Genus database with same CATH topology
 3F99 A;  3N2A A;  2BZL A;  3D1H A;  3S3K A;  1OHE A;  4ZN5 A;  4NWF A;  1NWL A;  4OHH A;  2M3V A;  1YFO A;  2CNH A;  3O4T A;  1GFY A;  3QCK A;  1JBW A;  2F70 A;  2HC2 A;  4QBW A;  1G4U S;  2BV5 A;  1YTW A;  4GE2 A;  2NZ6 A;  1U25 A;  2Y66 A;  4JNB A;  4R0S A;  3V0I A;  2G6Z A;  4KI9 A;  4RI5 A;  1T49 A;  5BZZ A;  2I6P A;  5MMZ B;  2C46 A;  2VEU A;  4PYH A;  2VEY A;  5BZX A;  1P3D A;  2H02 A;  1M3G A;  1EEN A;  5BUG A;  2VTD A;  3F41 A;  4GWF A;  1P31 A;  4D3P A;  1C85 A;  2HC1 A;  4WOH A;  1J6U A;  4C13 A;  4C12 A;  1C84 A;  2JJD A;  4GRY A;  4QF5 A;  1I9T A;  4HRF A;  1PTV A;  2I6M A;  5KA0 A;  2AM1 A;  2ZN7 A;  3QCD A;  4R0T A;  1U24 A;  5M43 A;  5KA7 A;  4OHD A;  4NYH A;  1WAX A;  1L8G A;  3D1Q A;  3QCN A;  3I7Z A;  1EEH A;  1I9S A;  2GCB A;  2J16 B;  2E0T A;  1YN9 A;  3N0A A;  3B7O A;  1MKP A;  2B4O A;  5A5E A;  2XJA A;  5KA3 A;  4RH5 A;  4Z6B A;  3V0E A;  1OES A;  3BLT A;  4JMK A;  4AZ1 A;  2VEV A;  3O3L A;  4DGX A;  3HN7 A;  2PI7 A;  5KA1 A;  1D5R A;  4BUC A;  1ZCK A;  4D3R A;  4Y2E A;  1ZCL A;  2VOR A;  1OEV A;  2WGP A;  3BRH A;  3QCJ A;  3RZ2 A;  3A5J A;  4WU3 A;  3ZV2 A;  2MBC A;  3V0D A;  1Q6J A;  2R0B A;  5K9V A;  4Y14 A;  3BM8 A;  5HDE A;  3AWG A;  4ERC A;  2X5O A;  2Q47 A;  4YR8 B;  4H34 A;  2CM2 A;  4QUN A;  2GJT A;  2AM2 A;  5KA4 A;  4QDI A;  2CFV A;  2C7S A;  2OZ5 A;  4NX8 A;  2XPC A;  2H4K A;  2I6I A;  2ESB A;  1FPR A;  2Q05 A;  5AWX A;  2HNQ A;  3ZM5 A;  2CNI A;  2QCJ A;  4I8N A;  2CNF A;  4BPC A;  1X24 A;  4DGP A;  4BUB A;  4RDD A;  2B4S A;  1KAK A;  3MMJ A;  4HJP A;  2PBN A;  3QCE A;  4QBE A;  1YTN A;  3EAX A;  1G1H A;  2A8B A;  4GS0 A;  1PTU A;  4YAA A;  2CMB A;  3O5X A;  4UAG A;  3PYZ A;  1BZH A;  2AZR A;  2F71 A;  5KA9 A;  2QBQ A;  5KAD A;  4ZRT A;  4QAP A;  2AHS A;  3CWE A;  4GE5 A;  3EMU A;  3QKQ A;  1C88 A;  1OET A;  4OHL A;  2CMC A;  1YGU A;  2H03 A;  1G7F A;  1J4X A;  3V0H A;  2I6J A;  5IBM A;  1GQQ A;  3H2X A;  1T4J A;  2PT0 A;  2F6Z A;  5K22 A;  2I4E A;  1JF7 A;  2P6X A;  1XXP A;  4PVG A;  1PH0 A;  1Q6T A;  3OMH A;  2J17 A;  3V0J A;  2OC3 A;  1XRI A;  1YGR A;  1RPM A;  1LYV A;  3S3E A;  2I3U A;  2QBS A;  2UUP A;  2WJP A;  5IBS A;  1WRM A;  4NWG A;  3S4O A;  2I6O A;  3QCG A;  3PS5 A;  3D44 A;  1W78 A;  1Q6S A;  2P4D A;  3QKP A;  2I4G A;  1PTT A;  4CVL A;  2QBP A;  3ZM2 A;  1FQ1 A;  4ICZ A;  1SUG A;  3O4U A;  4QAH A;  2F6Y A;  4NND A;  3RGO A;  3QCI A;  2H4V A;  3RO1 A;  1OEU A;  4OHI A;  3V0F A;  4KYQ A;  1ZC0 A;  5A5F A;  1KAV A;  2I75 A;  4WTY A;  1WCH A;  1V3A A;  4S0G A;  2Y96 A;  2F6T A;  1QXK A;  2NTA A;  4JMJ A;  2BGE A;  2HNP A;  3M4U A;  1Q1M A;  3UAG A;  4GRZ A;  2BGD A;  2UAG A;  3AWE A;  4CVK A;  2CMA A;  5KAA A;  3MOZ A;  1C83 A;  1G1G A;  2CJZ A;  3ZM0 A;  1VHR A;  3D9C A;  2I4H A;  2QDP A;  2GC6 A;  3A5K A;  1L8K A;  2SHP A;  3SR9 A;  5GTJ A;  3GXG A;  3S4E A;  1T48 A;  2I42 A;  2B3O A;  1I57 A;  3EZZ A;  1ZZW A;  1G1F A;  4GFU A;  4RHG A;  1NO6 A;  4JBC A;  4BJO A;  4CVM A;  1OEO X;  1U26 A;  3QCC A;  1W7K A;  4ZIY A;  2YDU A;  4MBB A;  1JLN A;  1PYN A;  2G59 A;  1XBO A;  3SME A;  3QCM A;  4J51 A;  2Y2F A;  2NT7 A;  3I80 A;  2HB1 A;  4B04 A;  5KAB A;  1P15 A;  1ECV A;  1E8C A;  2Y1O A;  4R30 A;  2QDC A;  5LXQ B;  2CM7 A;  3LJ8 A;  2DXP A;  3GXH A;  2VOS A;  3QCF A;  3MVN A;  1PXH A;  4IKC A;  2PSZ A;  1QZ0 A;  1LQF A;  3ZMP A;  5K25 A;  2F00 A;  2OUD A;  1GQY A;  1YTS A;  3S3H A;  1EEO A;  1AAX A;  5J8R A;  3S3F A;  2PQ5 A;  2UUO A;  2A3K A;  2GP0 A;  2VEW A;  1GWZ A;  3CM3 A;  2GCA A;  1FGS A;  1BZC A;  3F9B A;  3EU0 A;  4QUM A;  4GFV A;  1PA9 A;  1PA1 A;  3MOW A;  2NV5 A;  1NL9 A;  2FH7 A;  1G4W R;  2OOQ A;  2JFF A;  2HXP A;  3ZM3 A;  5K9W A;  1G7G A;  3RGQ A;  2ZMM A;  1OHD A;  1OHC A;  5EHP A;  1A5Y A;  3NRS A;  3QCH A;  1Q6N A;  2CNE A;  2PA5 A;  5EHR A;  2CM3 A;  5KA2 A;  3ZMQ A;  4HJQ A;  1O5Z A;  1C86 A;  5BX1 A;  2I3R A;  1XXV A;  2QBR A;  1YWF A;  4H1O A;  3QCL A;  3BLU A;  3D1O A;  1UAG A;  2B49 A;  2QEP A;  1NNY A;  1PTY A;  2BIJ A;  1NWE A;  2Y68 A;  4TVV A;  4WU2 A;  2CNG A;  2B4P A;  1YPT A;  2QCT A;  5KA8 A;  2FJN A;  3ZL8 A;  1Q6P A;  1C87 A;  1ONY A;  2GWO A;  2IMG A;  3U96 A;  5K23 A;  3AWF A;  4RH9 A;  1LAR A;  2F46 A;  3OLR A;  1NZ7 A;  4GE6 A;  3QCB A;  1FPZ A;  5K24 A;  4D3Q A;  2WTZ A;  4RI4 A;  3NME A;  2JFH A;  2J16 A;  3O4S A;  1E0D A;  3QCZ A;  2VTE A;  3ZM1 A;  2B07 A;  4OHE A;  2H04 A;  2F6F A;  1ONZ A;  1GG4 A;  3EB1 A;  2HY3 A;  2HVL A;  2F6V A;  4KYR A;  2QDM A;  2H4G A;  1YZ4 A;  4ZI4 A;  1XM2 A;  3V0G A;  3F9A A;  1BZJ A;  2HCM A;  2CM8 A;  3LK7 A;  5KAC A;  2I1Y A;  3I36 A;  2NLK A;  1RXD A;  2RF6 A;  1Q6M A;  4RKK A;  2GC5 A;  3ZM6 A;  2VEX A;  3D42 A;  2I5X A;  2B4U A;  4HV4 A;  5I6V A;  1R6H A;  2F6W A;  2NT2 A;  2FJM A;  1OEM X;  2JFG A;  1JBV A;  3F81 A;  2Y67 A; 
#chains in the Genus database with same CATH homology
 3F99 A;  2BZL A;  3D1H A;  3S3K A;  1OHE A;  4ZN5 A;  4NWF A;  1NWL A;  4OHH A;  2M3V A;  1YFO A;  2CNH A;  3O4T A;  1GFY A;  3QCK A;  2F70 A;  2HC2 A;  4QBW A;  1G4U S;  2BV5 A;  1YTW A;  4GE2 A;  2NZ6 A;  1U25 A;  4JNB A;  4R0S A;  3V0I A;  2G6Z A;  4KI9 A;  4RI5 A;  1T49 A;  5BZZ A;  2I6P A;  5MMZ B;  2C46 A;  2VEU A;  4PYH A;  2VEY A;  5BZX A;  2H02 A;  1M3G A;  1EEN A;  5BUG A;  3F41 A;  4GWF A;  4D3P A;  1C85 A;  2HC1 A;  4WOH A;  1C84 A;  2JJD A;  4GRY A;  1I9T A;  4HRF A;  1PTV A;  2I6M A;  5KA0 A;  2ZN7 A;  3QCD A;  4R0T A;  1U24 A;  5M43 A;  5KA7 A;  4OHD A;  4NYH A;  1WAX A;  1L8G A;  3D1Q A;  3QCN A;  3I7Z A;  1I9S A;  2J16 B;  2E0T A;  1YN9 A;  3N0A A;  3B7O A;  1MKP A;  2B4O A;  5KA3 A;  4RH5 A;  4Z6B A;  3V0E A;  1OES A;  3BLT A;  4JMK A;  4AZ1 A;  2VEV A;  3O3L A;  4DGX A;  5KA1 A;  2PI7 A;  1D5R A;  1ZCK A;  4D3R A;  4Y2E A;  1ZCL A;  3QCJ A;  1OEV A;  2WGP A;  3BRH A;  3RZ2 A;  3A5J A;  4WU3 A;  3ZV2 A;  2MBC A;  3V0D A;  1Q6J A;  2R0B A;  5K9V A;  4Y14 A;  3BM8 A;  5HDE A;  3AWG A;  4ERC A;  2Q47 A;  4YR8 B;  4H34 A;  2CM2 A;  4QUN A;  2GJT A;  5KA4 A;  2CFV A;  2C7S A;  2OZ5 A;  4NX8 A;  2H4K A;  2I6I A;  2ESB A;  1FPR A;  2Q05 A;  5AWX A;  2HNQ A;  2CNI A;  2QCJ A;  4I8N A;  2CNF A;  4BPC A;  1X24 A;  4DGP A;  4RDD A;  2B4S A;  1KAK A;  3MMJ A;  4HJP A;  2PBN A;  3QCE A;  4QBE A;  1YTN A;  3EAX A;  1G1H A;  2A8B A;  4GS0 A;  1PTU A;  4YAA A;  2CMB A;  3O5X A;  1BZH A;  2AZR A;  2F71 A;  5KA9 A;  2QBQ A;  5KAD A;  4ZRT A;  4QAP A;  2AHS A;  3CWE A;  4GE5 A;  3EMU A;  3QKQ A;  1C88 A;  1OET A;  4OHL A;  2CMC A;  1YGU A;  2H03 A;  1G7F A;  1J4X A;  3V0H A;  2I6J A;  5IBM A;  3H2X A;  1T4J A;  2PT0 A;  2F6Z A;  5K22 A;  2I4E A;  1JF7 A;  2P6X A;  1XXP A;  4PVG A;  1PH0 A;  1Q6T A;  3OMH A;  2J17 A;  3V0J A;  2OC3 A;  1XRI A;  1YGR A;  1RPM A;  1LYV A;  3S3E A;  2I3U A;  2QBS A;  5IBS A;  1WRM A;  4NWG A;  3S4O A;  2I6O A;  3QCG A;  3PS5 A;  3D44 A;  1Q6S A;  2P4D A;  3QKP A;  2I4G A;  1PTT A;  2QBP A;  3ZM2 A;  1FQ1 A;  4ICZ A;  1SUG A;  3O4U A;  4QAH A;  2F6Y A;  4NND A;  3RGO A;  3QCI A;  2H4V A;  3RO1 A;  1OEU A;  4OHI A;  3V0F A;  4KYQ A;  1ZC0 A;  1KAV A;  2I75 A;  4WTY A;  1WCH A;  1V3A A;  4S0G A;  2Y96 A;  2F6T A;  1QXK A;  2NTA A;  4JMJ A;  2BGE A;  2HNP A;  3M4U A;  1Q1M A;  4GRZ A;  2BGD A;  3AWE A;  2CMA A;  5KAA A;  3MOZ A;  1C83 A;  1G1G A;  2CJZ A;  3ZM0 A;  1VHR A;  3D9C A;  2I4H A;  2QDP A;  3A5K A;  1L8K A;  2SHP A;  3SR9 A;  5GTJ A;  3GXG A;  3S4E A;  1T48 A;  2I42 A;  2B3O A;  1I57 A;  3EZZ A;  1ZZW A;  1G1F A;  4GFU A;  4RHG A;  1NO6 A;  4JBC A;  4BJO A;  1OEO X;  1U26 A;  3QCC A;  2YDU A;  4MBB A;  1JLN A;  1PYN A;  2G59 A;  1XBO A;  3SME A;  3QCM A;  4J51 A;  2Y2F A;  2NT7 A;  3I80 A;  2HB1 A;  4B04 A;  5KAB A;  1P15 A;  1ECV A;  4R30 A;  2QDC A;  5LXQ B;  2CM7 A;  3LJ8 A;  2DXP A;  3GXH A;  3QCF A;  1PXH A;  4IKC A;  2PSZ A;  1QZ0 A;  1LQF A;  3ZMP A;  5K25 A;  2OUD A;  1YTS A;  3S3H A;  1EEO A;  1AAX A;  5J8R A;  3S3F A;  2PQ5 A;  2A3K A;  2GP0 A;  2VEW A;  1GWZ A;  3CM3 A;  1BZC A;  3F9B A;  3EU0 A;  4QUM A;  4GFV A;  1PA9 A;  1PA1 A;  3MOW A;  2NV5 A;  1NL9 A;  2FH7 A;  1G4W R;  2OOQ A;  2HXP A;  3ZM3 A;  5K9W A;  1G7G A;  3RGQ A;  2ZMM A;  1OHD A;  1OHC A;  5EHP A;  1A5Y A;  3QCH A;  1Q6N A;  2CNE A;  2PA5 A;  5EHR A;  2CM3 A;  5KA2 A;  3ZMQ A;  4HJQ A;  1C86 A;  5BX1 A;  2I3R A;  1XXV A;  2QBR A;  1YWF A;  4H1O A;  3QCL A;  3BLU A;  3D1O A;  2B49 A;  2QEP A;  1NNY A;  1PTY A;  2BIJ A;  1NWE A;  4TVV A;  4WU2 A;  2CNG A;  2B4P A;  1YPT A;  2QCT A;  5KA8 A;  2FJN A;  1Q6P A;  1C87 A;  1ONY A;  2GWO A;  2IMG A;  3U96 A;  5K23 A;  3AWF A;  4RH9 A;  1LAR A;  2F46 A;  3OLR A;  1NZ7 A;  4GE6 A;  3QCB A;  1FPZ A;  5K24 A;  4D3Q A;  4RI4 A;  3NME A;  2J16 A;  3O4S A;  3ZM1 A;  2B07 A;  4OHE A;  2H04 A;  2F6F A;  1ONZ A;  3EB1 A;  2HY3 A;  2HVL A;  2F6V A;  4KYR A;  2QDM A;  2H4G A;  1YZ4 A;  4ZI4 A;  1XM2 A;  3V0G A;  3F9A A;  1BZJ A;  2HCM A;  2CM8 A;  5KAC A;  2I1Y A;  3I36 A;  2NLK A;  1RXD A;  2RF6 A;  1Q6M A;  4RKK A;  2VEX A;  3D42 A;  2I5X A;  2B4U A;  5I6V A;  1R6H A;  2F6W A;  2NT2 A;  2FJM A;  1OEM X;  3F81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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