2QDPA

Crystal structure of the heptp catalytic domain c270s mutant crystallized in ammonium acetate
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
292
structure length
292
Chain Sequence
NTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHSSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of substrate recognition by hematopoietic tyrosine phosphatase.
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 7
total genus 97
structure length 292
sequence length 292
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2qdpA00
2PT0A 3QKQA 1OETA 3F9BA 3EAXA 5KA2A 4B04A 4IKCA 2VEVA 3U96A 2PA5A 1NWEA 4RKKA 2J17A 2G6ZA 1RXDA 1Q6MA 2H4VA 4H34A 2GWOA 2PI7A 3S4EA 1G4WR 1BZJA 2HC1A 1YPTA 4RDDA 4NX8A 2ESBA 1Q1MA 2E0TA 5HDEA 1WAXA 4ZI4A 2I42A 3RZ2A 2NT7A 2IMGA 3B7OA 3RO1A 1PTTA 2CM3A 2VEXA 4OHLA 4QAHA 2C7SA 3QCJA 1PTUA 3BLTA 1YWFA 1BZHA 3BLUA 2P6XA 3EB1A 4H1OA 3F9AA 5KADA 3I80A 1WRMA 5K25A 4RI4A 2A3KA 5BZXA 1YFOA 2HNQA 3QCMA 2M3VA 1XRIA 4GRYA 2MBCA 5BZZA 2HC2A 1XM2A 5K24A 3H2XA 3D42A 4RI5A 2B07A 3ZM1A 3V0EA 2CNFA 3QCDA 2G59A 2I4HA 3S3FA 1G7FA 4WTYA 1Q6TA 2H4GA 4GS0A 3OMHA 3D9CA 3MOZA 2NLKA 1C83A 1X24A 1D5RA 2F6ZA 4QAPA 2I6JA 2QDCA 5I6VA 3CWEA 3O4UA 1V3AA 2I5XA 2A8BA 4R0SA 4R0TA 2BIJA 1MKPA 2J16A 3D1HA 2CNEA 2NT2A 1G1GA 3LJ8A 4QBEA 2HNPA 3BRHA 5KA1A 1JLNA 1ONYA 1G1HA 5K9WA 3M4UA 3CM3A 1BZCA 3QCHA 1QZ0A 3AWFA 2Y96A 1SUGA 2GP0A 4QBWA 2YDUA 1PH0A 3V0IA 4GFVA 4GFUA 1PA1A 5KA7A 3ZV2A 1T48A 2CM2A 2FJNA 2F70A 2CNHA 3D1OA 2Q47A 1R6HA 2OOQA 1YTWA 3MMJA 2HXPA 3QCKA 1G1FA 2ZN7A 1Q6SA 5EHPA 4OHIA 3QKPA 4DGXA 1I9TA 1U25A 4WU2A 3GXHA 1C86A 2B3OA 2F46A 2QBSA 2F6WA 2Y2FA 1U26A 3GXGA 2VEUA 4NWFA 1LQFA 2P4DA 4GE5A 1I57A 3S3EA 4NYHA 5KABA 4PYHA 2F6VA 2RF6A 3F41A 5MMZB 2I3RA 3PS5A 5K9VA 1YGUA 1A5YA 2HY3A 2BGDA 2AZRA 3I7ZA 1NZ7A 2I6MA 4JNBA 1XXVA 2FJMA 2PQ5A 1YZ4A 2I1YA 3O4TA 2QBPA 2F6TA 3ZM2A 4BPCA 1I9SA 1J4XA 2CMAA 1C84A 3EMUA 3S3HA 4ERCA 1WCHA 4HRFA 4KYRA 4Y2EA 3RGQA 1YTSA 1QXKA 1ZC0A 2NTAA 2HVLA 1G4US 1L8GA 2OZ5A 4Z6BA 3V0HA 2CM8A 5M43A 1PTYA 2NZ6A 4D3QA 3QCGA 2CMCA 2I75A 2B4UA 1PXHA 1OEOX 4NWGA 2CM7A 2AHSA 4MBBA 4GWFA 2CNIA 1AAXA 3N0AA 5BUGA 3A5KA 2CJZA 4KYQA 2OC3A 1LARA 1G7GA 2SHPA 3V0GA 3RGOA 5IBMA 3QCNA 2QCJA 2QCTA 2C46A 1Q6NA 4HJQA 4WU3A 1KAVA 1XXPA 3QCLA 1EEOA 2J16B 1T49A 3D1QA 1C85A 2DXPA 4JMKA 3QCIA 1OEMX 2H4KA 2ZMMA 4OHEA 4Y14A 2H03A 1T4JA 1C88A 2VEWA 2I6IA 5KA4A 2QDMA 5BX1A 2B4OA 1ZCKA 3F99A 4QUMA 4PVGA 2I4EA 3ZMQA 3S3KA 3O5XA 2GJTA 4NNDA 1Q6JA 3OLRA 4R30A 1NL9A 1VHRA 2F71A 1OEUA 3O3LA 1PTVA 4I8NA 3QCCA 4ICZA 5LXQB 2JJDA 4TVVA 1OHEA 3QCBA 2B49A 5KA0A 1YN9A 2BZLA 4D3RA 4WOHA 3AWGA 1NWLA 2OUDA 3BM8A 2BV5A 2NV5A 3F81A 1OESA 4QUNA 4YAAA 4HJPA 5J8RA 1C87A 4OHDA 5GTJA 3SMEA 2VEYA 4GE6A 3ZM3A 2CMBA 2I4GA 4RHGA 4GE2A 3QCFA 2R0BA 2QBRA 3SR9A 2H04A 4S0GA 3EU0A 4DGPA 1GWZA 5KA3A 2HCMA 4KI9A 2F6FA 5K22A 2HB1A 4ZRTA 1PA9A 1ONZA 2H02A 4JBCA 4AZ1A 2CFVA 2QBQA 5IBSA 1M3GA 2FH7A 3V0FA 3EZZA 1EENA 2PBNA 3A5JA 1FPRA 1JF7A 1NNYA 2B4PA 2I3UA 2WGPA 1Q6PA 1OHDA 4RH5A 1OHCA 4JMJA 3V0JA 3D44A 5AWXA 2CNGA 4J51A 3S4OA 5EHRA 1P15A 1FQ1A 3I36A 3O4SA 5KA9A 2I6OA 2QDPA 4GRZA 3NMEA 2I6PA 5KACA 1ZCLA 1YGRA 1LYVA 3ZM0A 4RH9A 1PYNA 1L8KA 1U24A 2Q05A 5KA8A 1XBOA 3V0DA 5K23A 2PSZA 3ZMPA 2F6YA 1OEVA 4OHHA 4D3PA 1NO6A 4BJOA 4YR8B 2QEPA 2B4SA 1GFYA 2BGEA 1RPMA 3AWEA 3MOWA 3QCEA 1ZZWA 5KAAA 1YTNA 1KAKA 4ZN5A 1FPZA 1ECVA
chains in the Genus database with same CATH superfamily
2PT0A 3QKQA 1OETA 3F9BA 3EAXA 5KA2A 4B04A 4IKCA 2Y66A 2VORA 2VEVA 3U96A 2PA5A 1NWEA 4RKKA 2F00A 1FGSA 2J17A 2G6ZA 1RXDA 1Q6MA 2H4VA 4H34A 2GWOA 2PI7A 3S4EA 1G4WR 4C12A 1BZJA 2HC1A 1YPTA 4RDDA 4NX8A 2ESBA 1Q1MA 2E0TA 5HDEA 1WAXA 4ZI4A 2I42A 3RZ2A 2NT7A 1W78A 2IMGA 3B7OA 3RO1A 1PTTA 2CM3A 2VEXA 2X5OA 4OHLA 4QAHA 2C7SA 3QCJA 1PTUA 2VOSA 4C13A 3BLTA 1YWFA 1BZHA 5A5FA 3BLUA 2P6XA 3EB1A 4H1OA 3F9AA 5KADA 3I80A 1WRMA 5K25A 4CVKA 1JBWA 2A3KA 4RI4A 5BZXA 1YFOA 2HNQA 4QDIA 3QCMA 2M3VA 1XRIA 4GRYA 2MBCA 2Y1OA 5BZZA 4BUCA 2HC2A 1XM2A 5K24A 3ZM6A 3H2XA 3D42A 4RI5A 2B07A 3ZM1A 3V0EA 2CNFA 3QCDA 2G59A 2I4HA 3S3FA 1G7FA 4WTYA 1Q6TA 2H4GA 4GS0A 3OMHA 3D9CA 3MOZA 2NLKA 1C83A 1X24A 1D5RA 2F6ZA 4QAPA 4UAGA 2Y68A 2I6JA 2QDCA 5I6VA 3CWEA 3O4UA 1V3AA 2I5XA 2A8BA 4R0SA 1P31A 2BIJA 4R0TA 1MKPA 2J16A 3D1HA 2CNEA 2NT2A 1G1GA 3LJ8A 4QBEA 2HNPA 3BRHA 3ZM5A 5KA1A 1JLNA 1ONYA 1G1HA 5K9WA 3M4UA 3CM3A 1BZCA 3QCHA 1QZ0A 3AWFA 2Y96A 1SUGA 2GP0A 4QBWA 2YDUA 1PH0A 3V0IA 4GFVA 4GFUA 1PA1A 5KA7A 3ZV2A 4ZIYA 1T48A 3QCZA 2CM2A 2FJNA 2F70A 2JFGA 3ZL8A 2CNHA 3D1OA 2Q47A 1R6HA 1P3DA 2OOQA 1YTWA 3MMJA 2HXPA 3QCKA 1G1FA 2ZN7A 1Q6SA 5EHPA 4OHIA 3QKPA 4DGXA 1I9TA 1U25A 4WU2A 3GXHA 1C86A 2B3OA 2F46A 2QBSA 2F6WA 2UUOA 2Y2FA 1U26A 3GXGA 2AM2A 2XPCA 2VEUA 4NWFA 1LQFA 2P4DA 4GE5A 1I57A 2JFFA 3S3EA 4NYHA 5KABA 4PYHA 2F6VA 2RF6A 3F41A 5MMZB 2I3RA 3PS5A 2VTEA 5K9VA 1YGUA 1A5YA 1O5ZA 2HY3A 2BGDA 2AZRA 3I7ZA 1NZ7A 2I6MA 4JNBA 1XXVA 2FJMA 2PQ5A 1YZ4A 2I1YA 3O4TA 2GCAA 2QBPA 2F6TA 3ZM2A 4BPCA 1I9SA 2XJAA 1J4XA 2CMAA 1C84A 3EMUA 4CVMA 3S3HA 4ERCA 1E8CA 1WCHA 3HN7A 2JFHA 4HRFA 4KYRA 4Y2EA 3RGQA 4QF5A 1YTSA 2GC5A 1QXKA 1ZC0A 2NTAA 2HVLA 2WJPA 1G4US 1L8GA 2OZ5A 2GCBA 4Z6BA 3V0HA 2CM8A 5M43A 1PTYA 2NZ6A 4D3QA 3QCGA 2CMCA 2I75A 2B4UA 1W7KA 1PXHA 3NRSA 1OEOX 4NWGA 2CM7A 2AHSA 4MBBA 4GWFA 2CNIA 1AAXA 3N0AA 5BUGA 2WTZA 3A5KA 2CJZA 4KYQA 2OC3A 1LARA 1G7GA 2SHPA 3V0GA 3RGOA 5IBMA 3QCNA 2QCJA 2QCTA 2C46A 1Q6NA 3N2AA 4HJQA 4WU3A 4HV4A 2GC6A 1KAVA 1XXPA 3QCLA 1EEOA 2J16B 1T49A 3D1QA 1C85A 2DXPA 4JMKA 1GQYA 2Y67A 3QCIA 1OEMX 2H4KA 2ZMMA 4OHEA 4Y14A 2H03A 1T4JA 1C88A 2VEWA 2I6IA 5KA4A 2QDMA 5BX1A 2B4OA 1ZCKA 3F99A 4QUMA 2VTDA 4PVGA 2I4EA 3ZMQA 3MVNA 2AM1A 1UAGA 3O5XA 3S3KA 2GJTA 4NNDA 1Q6JA 3OLRA 4BUBA 4R30A 1NL9A 1VHRA 2F71A 1OEUA 3O3LA 1PTVA 4I8NA 3QCCA 4ICZA 5LXQB 2JJDA 4TVVA 1OHEA 3QCBA 2B49A 5KA0A 1YN9A 2BZLA 4D3RA 4WOHA 3AWGA 1NWLA 2OUDA 3BM8A 2BV5A 2NV5A 3F81A 1OESA 4QUNA 4YAAA 4HJPA 5J8RA 5A5EA 1C87A 4OHDA 5GTJA 3SMEA 2VEYA 4GE6A 3ZM3A 2CMBA 2I4GA 4RHGA 4GE2A 3QCFA 2R0BA 2QBRA 3LK7A 3SR9A 2H04A 4S0GA 3EU0A 4DGPA 1GWZA 5KA3A 3PYZA 2HCMA 4KI9A 2F6FA 5K22A 2HB1A 4ZRTA 1PA9A 1ONZA 2UUPA 2H02A 4JBCA 4AZ1A 2CFVA 2QBQA 5IBSA 1M3GA 2FH7A 3V0FA 3EZZA 1EENA 2PBNA 3A5JA 1GG4A 1FPRA 1JF7A 1NNYA 2B4PA 2I3UA 2WGPA 1OHDA 1Q6PA 4RH5A 1OHCA 4JMJA 3V0JA 3D44A 5AWXA 2CNGA 2UAGA 4J51A 3S4OA 5EHRA 1P15A 1FQ1A 3I36A 3O4SA 5KA9A 2I6OA 1EEHA 2QDPA 4GRZA 3NMEA 2I6PA 5KACA 1JBVA 1GQQA 1ZCLA 1YGRA 1LYVA 3UAGA 3ZM0A 4RH9A 1PYNA 1L8KA 1U24A 2Q05A 5KA8A 1XBOA 3V0DA 5K23A 2PSZA 3ZMPA 2F6YA 1OEVA 4OHHA 4D3PA 1NO6A 4BJOA 4YR8B 2QEPA 2B4SA 1GFYA 4CVLA 2BGEA 1J6UA 1RPMA 3AWEA 3MOWA 3QCEA 1ZZWA 5KAAA 1YTNA 1E0DA 1KAKA 4ZN5A 1FPZA 1ECVA
chains in the Genus database with same CATH topology
2PT0A 3QKQA 1OETA 3F9BA 3EAXA 5KA2A 4B04A 4IKCA 2VEVA 3U96A 2PA5A 1NWEA 4RKKA 2J17A 2G6ZA 1RXDA 1Q6MA 2H4VA 4H34A 2GWOA 2PI7A 3S4EA 1G4WR 1BZJA 2HC1A 1YPTA 4RDDA 4NX8A 2ESBA 1Q1MA 2E0TA 5HDEA 1WAXA 4ZI4A 2I42A 3RZ2A 2NT7A 2IMGA 3B7OA 3RO1A 1PTTA 2CM3A 2VEXA 4OHLA 4QAHA 2C7SA 3QCJA 1PTUA 3BLTA 1YWFA 1BZHA 3BLUA 2P6XA 3EB1A 4H1OA 3F9AA 5KADA 3I80A 1WRMA 5K25A 4RI4A 2A3KA 5BZXA 1YFOA 2HNQA 3QCMA 2M3VA 1XRIA 4GRYA 2MBCA 5BZZA 2HC2A 1XM2A 5K24A 3H2XA 3D42A 4RI5A 2B07A 3ZM1A 3V0EA 2CNFA 3QCDA 2G59A 2I4HA 3S3FA 1G7FA 4WTYA 1Q6TA 2H4GA 4GS0A 3OMHA 3D9CA 3MOZA 2NLKA 1C83A 1X24A 1D5RA 2F6ZA 4QAPA 2I6JA 2QDCA 5I6VA 3CWEA 3O4UA 1V3AA 2I5XA 2A8BA 4R0SA 4R0TA 2BIJA 1MKPA 2J16A 3D1HA 2CNEA 2NT2A 1G1GA 3LJ8A 4QBEA 2HNPA 3BRHA 5KA1A 1JLNA 1ONYA 1G1HA 5K9WA 3M4UA 3CM3A 1BZCA 3QCHA 1QZ0A 3AWFA 2Y96A 1SUGA 2GP0A 4QBWA 2YDUA 1PH0A 3V0IA 4GFVA 4GFUA 1PA1A 5KA7A 3ZV2A 1T48A 2CM2A 2FJNA 2F70A 2CNHA 3D1OA 2Q47A 1R6HA 2OOQA 1YTWA 3MMJA 2HXPA 3QCKA 1G1FA 2ZN7A 1Q6SA 5EHPA 4OHIA 3QKPA 4DGXA 1I9TA 1U25A 4WU2A 3GXHA 1C86A 2B3OA 2F46A 2QBSA 2F6WA 2Y2FA 1U26A 3GXGA 2VEUA 4NWFA 1LQFA 2P4DA 4GE5A 1I57A 3S3EA 4NYHA 5KABA 4PYHA 2F6VA 2RF6A 3F41A 5MMZB 2I3RA 3PS5A 5K9VA 1YGUA 1A5YA 2HY3A 2BGDA 2AZRA 3I7ZA 1NZ7A 2I6MA 4JNBA 1XXVA 2FJMA 2PQ5A 1YZ4A 2I1YA 3O4TA 2QBPA 2F6TA 3ZM2A 4BPCA 1I9SA 1J4XA 2CMAA 1C84A 3EMUA 3S3HA 4ERCA 1WCHA 4HRFA 4KYRA 4Y2EA 3RGQA 1YTSA 1QXKA 1ZC0A 2NTAA 2HVLA 1G4US 1L8GA 2OZ5A 4Z6BA 3V0HA 2CM8A 5M43A 1PTYA 2NZ6A 4D3QA 3QCGA 2CMCA 2I75A 2B4UA 1PXHA 1OEOX 4NWGA 2CM7A 2AHSA 4MBBA 4GWFA 2CNIA 1AAXA 3N0AA 5BUGA 3A5KA 2CJZA 4KYQA 2OC3A 1LARA 1G7GA 2SHPA 3V0GA 3RGOA 5IBMA 3QCNA 2QCJA 2QCTA 2C46A 1Q6NA 4HJQA 4WU3A 1KAVA 1XXPA 3QCLA 1EEOA 2J16B 1T49A 3D1QA 1C85A 2DXPA 4JMKA 3QCIA 1OEMX 2H4KA 2ZMMA 4OHEA 4Y14A 2H03A 1T4JA 1C88A 2VEWA 2I6IA 5KA4A 2QDMA 5BX1A 2B4OA 1ZCKA 3F99A 4QUMA 4PVGA 2I4EA 3ZMQA 3S3KA 3O5XA 2GJTA 4NNDA 1Q6JA 3OLRA 4R30A 1NL9A 1VHRA 2F71A 1OEUA 3O3LA 1PTVA 4I8NA 3QCCA 4ICZA 5LXQB 2JJDA 4TVVA 1OHEA 3QCBA 2B49A 5KA0A 1YN9A 2BZLA 4D3RA 4WOHA 3AWGA 1NWLA 2OUDA 3BM8A 2BV5A 2NV5A 3F81A 1OESA 4QUNA 4YAAA 4HJPA 5J8RA 1C87A 4OHDA 5GTJA 3SMEA 2VEYA 4GE6A 3ZM3A 2CMBA 2I4GA 4RHGA 4GE2A 3QCFA 2R0BA 2QBRA 3SR9A 2H04A 4S0GA 3EU0A 4DGPA 1GWZA 5KA3A 2HCMA 4KI9A 2F6FA 5K22A 2HB1A 4ZRTA 1PA9A 1ONZA 2H02A 4JBCA 4AZ1A 2CFVA 2QBQA 5IBSA 1M3GA 2FH7A 3V0FA 3EZZA 1EENA 2PBNA 3A5JA 1FPRA 1JF7A 1NNYA 2B4PA 2I3UA 2WGPA 1Q6PA 1OHDA 4RH5A 1OHCA 4JMJA 3V0JA 3D44A 5AWXA 2CNGA 4J51A 3S4OA 5EHRA 1P15A 1FQ1A 3I36A 3O4SA 5KA9A 2I6OA 2QDPA 4GRZA 3NMEA 2I6PA 5KACA 1ZCLA 1YGRA 1LYVA 3ZM0A 4RH9A 1PYNA 1L8KA 1U24A 2Q05A 5KA8A 1XBOA 3V0DA 5K23A 2PSZA 3ZMPA 2F6YA 1OEVA 4OHHA 4D3PA 1NO6A 4BJOA 4YR8B 2QEPA 2B4SA 1GFYA 2BGEA 1RPMA 3AWEA 3MOWA 3QCEA 1ZZWA 5KAAA 1YTNA 1KAKA 4ZN5A 1FPZA 1ECVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PT0 A;  3QKQ A;  1OET A;  3F9B A;  3EAX A;  5KA2 A;  4B04 A;  4IKC A;  2VEV A;  3U96 A;  2PA5 A;  1NWE A;  4RKK A;  2J17 A;  2G6Z A;  1RXD A;  1Q6M A;  2H4V A;  4H34 A;  2GWO A;  2PI7 A;  3S4E A;  1G4W R;  1BZJ A;  2HC1 A;  1YPT A;  4RDD A;  4NX8 A;  2ESB A;  1Q1M A;  2E0T A;  5HDE A;  1WAX A;  4ZI4 A;  2I42 A;  3RZ2 A;  2NT7 A;  2IMG A;  3B7O A;  3RO1 A;  1PTT A;  2CM3 A;  2VEX A;  4OHL A;  4QAH A;  2C7S A;  3QCJ A;  1PTU A;  3BLT A;  1YWF A;  1BZH A;  3BLU A;  2P6X A;  3EB1 A;  4H1O A;  3F9A A;  5KAD A;  3I80 A;  1WRM A;  5K25 A;  4RI4 A;  2A3K A;  5BZX A;  1YFO A;  2HNQ A;  3QCM A;  2M3V A;  1XRI A;  4GRY A;  2MBC A;  5BZZ A;  2HC2 A;  1XM2 A;  5K24 A;  3H2X A;  3D42 A;  4RI5 A;  2B07 A;  3ZM1 A;  3V0E A;  2CNF A;  3QCD A;  2G59 A;  2I4H A;  3S3F A;  1G7F A;  4WTY A;  1Q6T A;  2H4G A;  4GS0 A;  3OMH A;  3D9C A;  3MOZ A;  2NLK A;  1C83 A;  1X24 A;  1D5R A;  2F6Z A;  4QAP A;  2I6J A;  2QDC A;  5I6V A;  3CWE A;  3O4U A;  1V3A A;  2I5X A;  2A8B A;  4R0S A;  4R0T A;  2BIJ A;  1MKP A;  2J16 A;  3D1H A;  2CNE A;  2NT2 A;  1G1G A;  3LJ8 A;  4QBE A;  2HNP A;  3BRH A;  5KA1 A;  1JLN A;  1ONY A;  1G1H A;  5K9W A;  3M4U A;  3CM3 A;  1BZC A;  3QCH A;  1QZ0 A;  3AWF A;  2Y96 A;  1SUG A;  2GP0 A;  4QBW A;  2YDU A;  1PH0 A;  3V0I A;  4GFV A;  4GFU A;  1PA1 A;  5KA7 A;  3ZV2 A;  1T48 A;  2CM2 A;  2FJN A;  2F70 A;  2CNH A;  3D1O A;  2Q47 A;  1R6H A;  2OOQ A;  1YTW A;  3MMJ A;  2HXP A;  3QCK A;  1G1F A;  2ZN7 A;  1Q6S A;  5EHP A;  4OHI A;  3QKP A;  4DGX A;  1I9T A;  1U25 A;  4WU2 A;  3GXH A;  1C86 A;  2B3O A;  2F46 A;  2QBS A;  2F6W A;  2Y2F A;  1U26 A;  3GXG A;  2VEU A;  4NWF A;  1LQF A;  2P4D A;  4GE5 A;  1I57 A;  3S3E A;  4NYH A;  5KAB A;  4PYH A;  2F6V A;  2RF6 A;  3F41 A;  5MMZ B;  2I3R A;  3PS5 A;  5K9V A;  1YGU A;  1A5Y A;  2HY3 A;  2BGD A;  2AZR A;  3I7Z A;  1NZ7 A;  2I6M A;  4JNB A;  1XXV A;  2FJM A;  2PQ5 A;  1YZ4 A;  2I1Y A;  3O4T A;  2QBP A;  2F6T A;  3ZM2 A;  4BPC A;  1I9S A;  1J4X A;  2CMA A;  1C84 A;  3EMU A;  3S3H A;  4ERC A;  1WCH A;  4HRF A;  4KYR A;  4Y2E A;  3RGQ A;  1YTS A;  1QXK A;  1ZC0 A;  2NTA A;  2HVL A;  1G4U S;  1L8G A;  2OZ5 A;  4Z6B A;  3V0H A;  2CM8 A;  5M43 A;  1PTY A;  2NZ6 A;  4D3Q A;  3QCG A;  2CMC A;  2I75 A;  2B4U A;  1PXH A;  1OEO X;  4NWG A;  2CM7 A;  2AHS A;  4MBB A;  4GWF A;  2CNI A;  1AAX A;  3N0A A;  5BUG A;  3A5K A;  2CJZ A;  4KYQ A;  2OC3 A;  1LAR A;  1G7G A;  2SHP A;  3V0G A;  3RGO A;  5IBM A;  3QCN A;  2QCJ A;  2QCT A;  2C46 A;  1Q6N A;  4HJQ A;  4WU3 A;  1KAV A;  1XXP A;  3QCL A;  1EEO A;  2J16 B;  1T49 A;  3D1Q A;  1C85 A;  2DXP A;  4JMK A;  3QCI A;  1OEM X;  2H4K A;  2ZMM A;  4OHE A;  4Y14 A;  2H03 A;  1T4J A;  1C88 A;  2VEW A;  2I6I A;  5KA4 A;  2QDM A;  5BX1 A;  2B4O A;  1ZCK A;  3F99 A;  4QUM A;  4PVG A;  2I4E A;  3ZMQ A;  3S3K A;  3O5X A;  2GJT A;  4NND A;  1Q6J A;  3OLR A;  4R30 A;  1NL9 A;  1VHR A;  2F71 A;  1OEU A;  3O3L A;  1PTV A;  4I8N A;  3QCC A;  4ICZ A;  5LXQ B;  2JJD A;  4TVV A;  1OHE A;  3QCB A;  2B49 A;  5KA0 A;  1YN9 A;  2BZL A;  4D3R A;  4WOH A;  3AWG A;  1NWL A;  2OUD A;  3BM8 A;  2BV5 A;  2NV5 A;  3F81 A;  1OES A;  4QUN A;  4YAA A;  4HJP A;  5J8R A;  1C87 A;  4OHD A;  5GTJ A;  3SME A;  2VEY A;  4GE6 A;  3ZM3 A;  2CMB A;  2I4G A;  4RHG A;  4GE2 A;  3QCF A;  2R0B A;  2QBR A;  3SR9 A;  2H04 A;  4S0G A;  3EU0 A;  4DGP A;  1GWZ A;  5KA3 A;  2HCM A;  4KI9 A;  2F6F A;  5K22 A;  2HB1 A;  4ZRT A;  1PA9 A;  1ONZ A;  2H02 A;  4JBC A;  4AZ1 A;  2CFV A;  2QBQ A;  5IBS A;  1M3G A;  2FH7 A;  3V0F A;  3EZZ A;  1EEN A;  2PBN A;  3A5J A;  1FPR A;  1JF7 A;  1NNY A;  2B4P A;  2I3U A;  2WGP A;  1Q6P A;  1OHD A;  4RH5 A;  1OHC A;  4JMJ A;  3V0J A;  3D44 A;  5AWX A;  2CNG A;  4J51 A;  3S4O A;  5EHR A;  1P15 A;  1FQ1 A;  3I36 A;  3O4S A;  5KA9 A;  2I6O A;  2QDP A;  4GRZ A;  3NME A;  2I6P A;  5KAC A;  1ZCL A;  1YGR A;  1LYV A;  3ZM0 A;  4RH9 A;  1PYN A;  1L8K A;  1U24 A;  2Q05 A;  5KA8 A;  1XBO A;  3V0D A;  5K23 A;  2PSZ A;  3ZMP A;  2F6Y A;  1OEV A;  4OHH A;  4D3P A;  1NO6 A;  4BJO A;  4YR8 B;  2QEP A;  2B4S A;  1GFY A;  2BGE A;  1RPM A;  3AWE A;  3MOW A;  3QCE A;  1ZZW A;  5KAA A;  1YTN A;  1KAK A;  4ZN5 A;  1FPZ A;  1ECV A; 
#chains in the Genus database with same CATH topology
 2PT0 A;  3QKQ A;  1OET A;  3F9B A;  3EAX A;  5KA2 A;  4B04 A;  4IKC A;  2Y66 A;  2VOR A;  2VEV A;  3U96 A;  2PA5 A;  1NWE A;  4RKK A;  2F00 A;  1FGS A;  2J17 A;  2G6Z A;  1RXD A;  1Q6M A;  2H4V A;  4H34 A;  2GWO A;  2PI7 A;  3S4E A;  1G4W R;  4C12 A;  1BZJ A;  2HC1 A;  1YPT A;  4RDD A;  4NX8 A;  2ESB A;  1Q1M A;  2E0T A;  5HDE A;  1WAX A;  4ZI4 A;  2I42 A;  3RZ2 A;  2NT7 A;  1W78 A;  2IMG A;  3B7O A;  3RO1 A;  1PTT A;  2CM3 A;  2VEX A;  2X5O A;  4OHL A;  4QAH A;  2C7S A;  3QCJ A;  1PTU A;  2VOS A;  4C13 A;  3BLT A;  1YWF A;  1BZH A;  5A5F A;  3BLU A;  2P6X A;  3EB1 A;  4H1O A;  3F9A A;  5KAD A;  3I80 A;  1WRM A;  5K25 A;  4CVK A;  1JBW A;  2A3K A;  4RI4 A;  5BZX A;  1YFO A;  2HNQ A;  4QDI A;  3QCM A;  2M3V A;  1XRI A;  4GRY A;  2MBC A;  2Y1O A;  5BZZ A;  4BUC A;  2HC2 A;  1XM2 A;  5K24 A;  3ZM6 A;  3H2X A;  3D42 A;  4RI5 A;  2B07 A;  3ZM1 A;  3V0E A;  2CNF A;  3QCD A;  2G59 A;  2I4H A;  3S3F A;  1G7F A;  4WTY A;  1Q6T A;  2H4G A;  4GS0 A;  3OMH A;  3D9C A;  3MOZ A;  2NLK A;  1C83 A;  1X24 A;  1D5R A;  2F6Z A;  4QAP A;  4UAG A;  2Y68 A;  2I6J A;  2QDC A;  5I6V A;  3CWE A;  3O4U A;  1V3A A;  2I5X A;  2A8B A;  4R0S A;  1P31 A;  2BIJ A;  4R0T A;  1MKP A;  2J16 A;  3D1H A;  2CNE A;  2NT2 A;  1G1G A;  3LJ8 A;  4QBE A;  2HNP A;  3BRH A;  3ZM5 A;  5KA1 A;  1JLN A;  1ONY A;  1G1H A;  5K9W A;  3M4U A;  3CM3 A;  1BZC A;  3QCH A;  1QZ0 A;  3AWF A;  2Y96 A;  1SUG A;  2GP0 A;  4QBW A;  2YDU A;  1PH0 A;  3V0I A;  4GFV A;  4GFU A;  1PA1 A;  5KA7 A;  3ZV2 A;  4ZIY A;  1T48 A;  3QCZ A;  2CM2 A;  2FJN A;  2F70 A;  2JFG A;  3ZL8 A;  2CNH A;  3D1O A;  2Q47 A;  1R6H A;  1P3D A;  2OOQ A;  1YTW A;  3MMJ A;  2HXP A;  3QCK A;  1G1F A;  2ZN7 A;  1Q6S A;  5EHP A;  4OHI A;  3QKP A;  4DGX A;  1I9T A;  1U25 A;  4WU2 A;  3GXH A;  1C86 A;  2B3O A;  2F46 A;  2QBS A;  2F6W A;  2UUO A;  2Y2F A;  1U26 A;  3GXG A;  2AM2 A;  2XPC A;  2VEU A;  4NWF A;  1LQF A;  2P4D A;  4GE5 A;  1I57 A;  2JFF A;  3S3E A;  4NYH A;  5KAB A;  4PYH A;  2F6V A;  2RF6 A;  3F41 A;  5MMZ B;  2I3R A;  3PS5 A;  2VTE A;  5K9V A;  1YGU A;  1A5Y A;  1O5Z A;  2HY3 A;  2BGD A;  2AZR A;  3I7Z A;  1NZ7 A;  2I6M A;  4JNB A;  1XXV A;  2FJM A;  2PQ5 A;  1YZ4 A;  2I1Y A;  3O4T A;  2GCA A;  2QBP A;  2F6T A;  3ZM2 A;  4BPC A;  1I9S A;  2XJA A;  1J4X A;  2CMA A;  1C84 A;  3EMU A;  4CVM A;  3S3H A;  4ERC A;  1E8C A;  1WCH A;  3HN7 A;  2JFH A;  4HRF A;  4KYR A;  4Y2E A;  3RGQ A;  4QF5 A;  1YTS A;  2GC5 A;  1QXK A;  1ZC0 A;  2NTA A;  2HVL A;  2WJP A;  1G4U S;  1L8G A;  2OZ5 A;  2GCB A;  4Z6B A;  3V0H A;  2CM8 A;  5M43 A;  1PTY A;  2NZ6 A;  4D3Q A;  3QCG A;  2CMC A;  2I75 A;  2B4U A;  1W7K A;  1PXH A;  3NRS A;  1OEO X;  4NWG A;  2CM7 A;  2AHS A;  4MBB A;  4GWF A;  2CNI A;  1AAX A;  3N0A A;  5BUG A;  2WTZ A;  3A5K A;  2CJZ A;  4KYQ A;  2OC3 A;  1LAR A;  1G7G A;  2SHP A;  3V0G A;  3RGO A;  5IBM A;  3QCN A;  2QCJ A;  2QCT A;  2C46 A;  1Q6N A;  3N2A A;  4HJQ A;  4WU3 A;  4HV4 A;  2GC6 A;  1KAV A;  1XXP A;  3QCL A;  1EEO A;  2J16 B;  1T49 A;  3D1Q A;  1C85 A;  2DXP A;  4JMK A;  1GQY A;  2Y67 A;  3QCI A;  1OEM X;  2H4K A;  2ZMM A;  4OHE A;  4Y14 A;  2H03 A;  1T4J A;  1C88 A;  2VEW A;  2I6I A;  5KA4 A;  2QDM A;  5BX1 A;  2B4O A;  1ZCK A;  3F99 A;  4QUM A;  2VTD A;  4PVG A;  2I4E A;  3ZMQ A;  3MVN A;  2AM1 A;  1UAG A;  3O5X A;  3S3K A;  2GJT A;  4NND A;  1Q6J A;  3OLR A;  4BUB A;  4R30 A;  1NL9 A;  1VHR A;  2F71 A;  1OEU A;  3O3L A;  1PTV A;  4I8N A;  3QCC A;  4ICZ A;  5LXQ B;  2JJD A;  4TVV A;  1OHE A;  3QCB A;  2B49 A;  5KA0 A;  1YN9 A;  2BZL A;  4D3R A;  4WOH A;  3AWG A;  1NWL A;  2OUD A;  3BM8 A;  2BV5 A;  2NV5 A;  3F81 A;  1OES A;  4QUN A;  4YAA A;  4HJP A;  5J8R A;  5A5E A;  1C87 A;  4OHD A;  5GTJ A;  3SME A;  2VEY A;  4GE6 A;  3ZM3 A;  2CMB A;  2I4G A;  4RHG A;  4GE2 A;  3QCF A;  2R0B A;  2QBR A;  3LK7 A;  3SR9 A;  2H04 A;  4S0G A;  3EU0 A;  4DGP A;  1GWZ A;  5KA3 A;  3PYZ A;  2HCM A;  4KI9 A;  2F6F A;  5K22 A;  2HB1 A;  4ZRT A;  1PA9 A;  1ONZ A;  2UUP A;  2H02 A;  4JBC A;  4AZ1 A;  2CFV A;  2QBQ A;  5IBS A;  1M3G A;  2FH7 A;  3V0F A;  3EZZ A;  1EEN A;  2PBN A;  3A5J A;  1GG4 A;  1FPR A;  1JF7 A;  1NNY A;  2B4P A;  2I3U A;  2WGP A;  1OHD A;  1Q6P A;  4RH5 A;  1OHC A;  4JMJ A;  3V0J A;  3D44 A;  5AWX A;  2CNG A;  2UAG A;  4J51 A;  3S4O A;  5EHR A;  1P15 A;  1FQ1 A;  3I36 A;  3O4S A;  5KA9 A;  2I6O A;  1EEH A;  2QDP A;  4GRZ A;  3NME A;  2I6P A;  5KAC A;  1JBV A;  1GQQ A;  1ZCL A;  1YGR A;  1LYV A;  3UAG A;  3ZM0 A;  4RH9 A;  1PYN A;  1L8K A;  1U24 A;  2Q05 A;  5KA8 A;  1XBO A;  3V0D A;  5K23 A;  2PSZ A;  3ZMP A;  2F6Y A;  1OEV A;  4OHH A;  4D3P A;  1NO6 A;  4BJO A;  4YR8 B;  2QEP A;  2B4S A;  1GFY A;  4CVL A;  2BGE A;  1J6U A;  1RPM A;  3AWE A;  3MOW A;  3QCE A;  1ZZW A;  5KAA A;  1YTN A;  1E0D A;  1KAK A;  4ZN5 A;  1FPZ A;  1ECV A; 
#chains in the Genus database with same CATH homology
 2PT0 A;  3QKQ A;  1OET A;  3F9B A;  3EAX A;  5KA2 A;  4B04 A;  4IKC A;  2VEV A;  3U96 A;  2PA5 A;  1NWE A;  4RKK A;  2J17 A;  2G6Z A;  1RXD A;  1Q6M A;  2H4V A;  4H34 A;  2GWO A;  2PI7 A;  3S4E A;  1G4W R;  1BZJ A;  2HC1 A;  1YPT A;  4RDD A;  4NX8 A;  2ESB A;  1Q1M A;  2E0T A;  5HDE A;  1WAX A;  4ZI4 A;  2I42 A;  3RZ2 A;  2NT7 A;  2IMG A;  3B7O A;  3RO1 A;  1PTT A;  2CM3 A;  2VEX A;  4OHL A;  4QAH A;  2C7S A;  3QCJ A;  1PTU A;  3BLT A;  1YWF A;  1BZH A;  3BLU A;  2P6X A;  3EB1 A;  4H1O A;  3F9A A;  5KAD A;  3I80 A;  1WRM A;  5K25 A;  4RI4 A;  2A3K A;  5BZX A;  1YFO A;  2HNQ A;  3QCM A;  2M3V A;  1XRI A;  4GRY A;  2MBC A;  5BZZ A;  2HC2 A;  1XM2 A;  5K24 A;  3H2X A;  3D42 A;  4RI5 A;  2B07 A;  3ZM1 A;  3V0E A;  2CNF A;  3QCD A;  2G59 A;  2I4H A;  3S3F A;  1G7F A;  4WTY A;  1Q6T A;  2H4G A;  4GS0 A;  3OMH A;  3D9C A;  3MOZ A;  2NLK A;  1C83 A;  1X24 A;  1D5R A;  2F6Z A;  4QAP A;  2I6J A;  2QDC A;  5I6V A;  3CWE A;  3O4U A;  1V3A A;  2I5X A;  2A8B A;  4R0S A;  4R0T A;  2BIJ A;  1MKP A;  2J16 A;  3D1H A;  2CNE A;  2NT2 A;  1G1G A;  3LJ8 A;  4QBE A;  2HNP A;  3BRH A;  5KA1 A;  1JLN A;  1ONY A;  1G1H A;  5K9W A;  3M4U A;  3CM3 A;  1BZC A;  3QCH A;  1QZ0 A;  3AWF A;  2Y96 A;  1SUG A;  2GP0 A;  4QBW A;  2YDU A;  1PH0 A;  3V0I A;  4GFV A;  4GFU A;  1PA1 A;  5KA7 A;  3ZV2 A;  1T48 A;  2CM2 A;  2FJN A;  2F70 A;  2CNH A;  3D1O A;  2Q47 A;  1R6H A;  2OOQ A;  1YTW A;  3MMJ A;  2HXP A;  3QCK A;  1G1F A;  2ZN7 A;  1Q6S A;  5EHP A;  4OHI A;  3QKP A;  4DGX A;  1I9T A;  1U25 A;  4WU2 A;  3GXH A;  1C86 A;  2B3O A;  2F46 A;  2QBS A;  2F6W A;  2Y2F A;  1U26 A;  3GXG A;  2VEU A;  4NWF A;  1LQF A;  2P4D A;  4GE5 A;  1I57 A;  3S3E A;  4NYH A;  5KAB A;  4PYH A;  2F6V A;  2RF6 A;  3F41 A;  5MMZ B;  2I3R A;  3PS5 A;  5K9V A;  1YGU A;  1A5Y A;  2HY3 A;  2BGD A;  2AZR A;  3I7Z A;  1NZ7 A;  2I6M A;  4JNB A;  1XXV A;  2FJM A;  2PQ5 A;  1YZ4 A;  2I1Y A;  3O4T A;  2QBP A;  2F6T A;  3ZM2 A;  4BPC A;  1I9S A;  1J4X A;  2CMA A;  1C84 A;  3EMU A;  3S3H A;  4ERC A;  1WCH A;  4HRF A;  4KYR A;  4Y2E A;  3RGQ A;  1YTS A;  1QXK A;  1ZC0 A;  2NTA A;  2HVL A;  1G4U S;  1L8G A;  2OZ5 A;  4Z6B A;  3V0H A;  2CM8 A;  5M43 A;  1PTY A;  2NZ6 A;  4D3Q A;  3QCG A;  2CMC A;  2I75 A;  2B4U A;  1PXH A;  1OEO X;  4NWG A;  2CM7 A;  2AHS A;  4MBB A;  4GWF A;  2CNI A;  1AAX A;  3N0A A;  5BUG A;  3A5K A;  2CJZ A;  4KYQ A;  2OC3 A;  1LAR A;  1G7G A;  2SHP A;  3V0G A;  3RGO A;  5IBM A;  3QCN A;  2QCJ A;  2QCT A;  2C46 A;  1Q6N A;  4HJQ A;  4WU3 A;  1KAV A;  1XXP A;  3QCL A;  1EEO A;  2J16 B;  1T49 A;  3D1Q A;  1C85 A;  2DXP A;  4JMK A;  3QCI A;  1OEM X;  2H4K A;  2ZMM A;  4OHE A;  4Y14 A;  2H03 A;  1T4J A;  1C88 A;  2VEW A;  2I6I A;  5KA4 A;  2QDM A;  5BX1 A;  2B4O A;  1ZCK A;  3F99 A;  4QUM A;  4PVG A;  2I4E A;  3ZMQ A;  3S3K A;  3O5X A;  2GJT A;  4NND A;  1Q6J A;  3OLR A;  4R30 A;  1NL9 A;  1VHR A;  2F71 A;  1OEU A;  3O3L A;  1PTV A;  4I8N A;  3QCC A;  4ICZ A;  5LXQ B;  2JJD A;  4TVV A;  1OHE A;  3QCB A;  2B49 A;  5KA0 A;  1YN9 A;  2BZL A;  4D3R A;  4WOH A;  3AWG A;  1NWL A;  2OUD A;  3BM8 A;  2BV5 A;  2NV5 A;  3F81 A;  1OES A;  4QUN A;  4YAA A;  4HJP A;  5J8R A;  1C87 A;  4OHD A;  5GTJ A;  3SME A;  2VEY A;  4GE6 A;  3ZM3 A;  2CMB A;  2I4G A;  4RHG A;  4GE2 A;  3QCF A;  2R0B A;  2QBR A;  3SR9 A;  2H04 A;  4S0G A;  3EU0 A;  4DGP A;  1GWZ A;  5KA3 A;  2HCM A;  4KI9 A;  2F6F A;  5K22 A;  2HB1 A;  4ZRT A;  1PA9 A;  1ONZ A;  2H02 A;  4JBC A;  4AZ1 A;  2CFV A;  2QBQ A;  5IBS A;  1M3G A;  2FH7 A;  3V0F A;  3EZZ A;  1EEN A;  2PBN A;  3A5J A;  1FPR A;  1JF7 A;  1NNY A;  2B4P A;  2I3U A;  2WGP A;  1Q6P A;  1OHD A;  4RH5 A;  1OHC A;  4JMJ A;  3V0J A;  3D44 A;  5AWX A;  2CNG A;  4J51 A;  3S4O A;  5EHR A;  1P15 A;  1FQ1 A;  3I36 A;  3O4S A;  5KA9 A;  2I6O A;  2QDP A;  4GRZ A;  3NME A;  2I6P A;  5KAC A;  1ZCL A;  1YGR A;  1LYV A;  3ZM0 A;  4RH9 A;  1PYN A;  1L8K A;  1U24 A;  2Q05 A;  5KA8 A;  1XBO A;  3V0D A;  5K23 A;  2PSZ A;  3ZMP A;  2F6Y A;  1OEV A;  4OHH A;  4D3P A;  1NO6 A;  4BJO A;  4YR8 B;  2QEP A;  2B4S A;  1GFY A;  2BGE A;  1RPM A;  3AWE A;  3MOW A;  3QCE A;  1ZZW A;  5KAA A;  1YTN A;  1KAK A;  4ZN5 A;  1FPZ A;  1ECV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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