2VEVA

Crystal strucutre of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
298
structure length
298
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Isothiazolidinone Inhibitors of Ptp1B Containing Imidazoles and Imidazolines
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 102
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2vevA00
3AWFA 1C83A 3QCFA 4GWFA 1LARA 2I42A 1G1FA 1G4WR 4GE6A 3EU0A 5IBMA 1PYNA 1T4JA 2VEXA 2GP0A 2MBCA 3BM8A 4WOHA 2PQ5A 2HB1A 1OHDA 4GS0A 3CWEA 3SR9A 2B4SA 2NT7A 3F9AA 4NWFA 3S3EA 3ZMQA 5K23A 3H2XA 2BGEA 3D9CA 2HNPA 2CM7A 2B49A 1XXPA 3BRHA 1X24A 2NV5A 2M3VA 3CM3A 5KA2A 4I8NA 3O4SA 2F46A 2HVLA 1XBOA 5KA7A 1I9SA 3QCKA 3S3KA 2BIJA 2I1YA 3V0EA 4RH5A 3I7ZA 3V0IA 2F6TA 2F6VA 1C88A 2VEWA 4OHHA 2I4EA 4QBWA 2QCTA 3QKQA 1ZZWA 1C85A 4DGXA 2HC2A 1NL9A 2G59A 2NTAA 1PH0A 2QCJA 4KI9A 2B4PA 4RH9A 1BZJA 4JBCA 3S4OA 3S4EA 3V0JA 1XXVA 3M4UA 2FH7A 5KACA 1Q6SA 2J16B 2B07A 5LXQB 1YZ4A 4RKKA 4H34A 3I80A 1YTNA 1YTSA 3O3LA 3O5XA 2CM8A 2I3UA 2I75A 2J16A 5KA4A 1OETA 2B4UA 4BJOA 5KA8A 3QCIA 2HNQA 5KA0A 3QCBA 2HC1A 2I4GA 4KYRA 3QCMA 4YR8B 1KAVA 1V3AA 4OHLA 3A5KA 5EHRA 4WU2A 1YGUA 1L8GA 2DXPA 3AWGA 4AZ1A 3QCCA 1R6HA 1AAXA 2CMBA 3BLTA 1YTWA 3O4UA 2CNHA 3EB1A 1WCHA 2I5XA 4PYHA 4GFVA 4ZRTA 4IKCA 1PTVA 1NWEA 3OLRA 4BPCA 5BZXA 1EEOA 5KA9A 4RDDA 2PI7A 3N0AA 3O4TA 3LJ8A 1Q6NA 2AZRA 2CNGA 4WU3A 5KA1A 3I36A 1PTTA 1Q1MA 1I57A 2H4GA 1J4XA 2QBPA 2P6XA 3D42A 3QCNA 3V0FA 2Q47A 3F81A 2OZ5A 3OMHA 1VHRA 2VEYA 5KADA 2I6JA 2GJTA 2NT2A 2I6IA 4NNDA 2CMCA 4R0TA 1G7GA 3QCHA 1OEOX 2CNFA 5I6VA 4YAAA 3A5JA 1OEVA 2I6PA 4ZI4A 2PA5A 2I4HA 5BX1A 3F99A 1I9TA 1G4US 2HY3A 5K24A 3RO1A 3ZMPA 2PT0A 4NWGA 1GFYA 1OHEA 1P15A 2QBSA 3F41A 2I6MA 2OOQA 1G1GA 3S3FA 1C86A 3PS5A 2H4KA 2F71A 2Y2FA 1A5YA 3V0DA 3SMEA 1WAXA 2PBNA 1LQFA 3ZV2A 4MBBA 3RZ2A 2VEVA 2BV5A 2PSZA 1C84A 2H02A 2P4DA 1ONYA 5K9VA 5BZZA 2WGPA 2FJNA 5J8RA 3QCEA 1RPMA 2CJZA 3MOWA 1BZCA 1YFOA 2NLKA 1XRIA 4ERCA 3ZM2A 3B7OA 4R30A 2CNEA 1SUGA 4D3QA 2B3OA 1OESA 5AWXA 2QDPA 3GXHA 4Z6BA 1PTYA 2JJDA 1MKPA 1RXDA 1T49A 3ZM0A 3EMUA 4HJPA 2FJMA 1Q6JA 2ZN7A 1U25A 2J17A 3D44A 4Y2EA 1QZ0A 4QAPA 2F6YA 1NWLA 3S3HA 1QXKA 4HRFA 2OC3A 3F9BA 1D5RA 2I3RA 1LYVA 4GE5A 4S0GA 3BLUA 3EAXA 3U96A 5KA3A 2RF6A 5MMZB 4QUNA 2F70A 2CNIA 4KYQA 1M3GA 2QEPA 2C7SA 1U24A 2R0BA 4R0SA 1FPZA 2A3KA 1NNYA 2NZ6A 1PA9A 2VEUA 1Q6TA 2CFVA 3QCGA 4NX8A 1YPTA 4OHEA 3QKPA 1BZHA 1G7FA 2B4OA 4D3RA 3QCLA 3QCJA 4RHGA 2F6WA 1C87A 5HDEA 1YGRA 1FPRA 2G6ZA 3D1HA 5EHPA 3MOZA 4GRZA 2F6ZA 4OHDA 2BZLA 2ZMMA 4TVVA 1EENA 2I6OA 1ONZA 4WTYA 5K22A 1WRMA 4QAHA 4OHIA 1PXHA 4J51A 4PVGA 2H03A 4DGPA 1L8KA 4GFUA 2AHSA 2OUDA 2E0TA 1PTUA 1OHCA 1XM2A 4B04A 2CMAA 2C46A 2CM3A 2HCMA 4RI4A 4ICZA 2QBQA 4GRYA 1YWFA 2QDCA 1U26A 4GE2A 2CM2A 1NZ7A 2H4VA 1FQ1A 1ZC0A 3QCDA 2Q05A 1PA1A 3RGOA 1JLNA 4HJQA 2ESBA 5BUGA 5KABA 4D3PA 4H1OA 1OEUA 3NMEA 5IBSA 2YDUA 3AWEA 1KAKA 1Q6PA 1G1HA 1ZCLA 3V0GA 3V0HA 3ZM3A 2Y96A 2HXPA 4QBEA 4Y14A 2A8BA 1YN9A 2IMGA 4JNBA 5K25A 2QBRA 3GXGA 3EZZA 1NO6A 1OEMX 1Q6MA 1GWZA 5K9WA 5GTJA 4QUMA 1ZCKA 2SHPA 3D1QA 3ZM1A 5M43A 4NYHA 2GWOA 1JF7A 1ECVA 4ZN5A 4JMJA 2H04A 1T48A 2QDMA 2F6FA 4JMKA 3MMJA 3RGQA 2BGDA 4RI5A 3D1OA 5KAAA
chains in the Genus database with same CATH superfamily
3AWFA 1C83A 3QCFA 4BUBA 4GWFA 1LARA 2I42A 1G1FA 1G4WR 4GE6A 3EU0A 5IBMA 1PYNA 1T4JA 2VEXA 2GP0A 2MBCA 3BM8A 4WOHA 2PQ5A 2HB1A 1OHDA 4GS0A 3CWEA 3SR9A 2B4SA 2NT7A 2X5OA 3F9AA 4NWFA 3S3EA 3ZMQA 5K23A 2UAGA 3H2XA 2BGEA 4C12A 3D9CA 2HNPA 2CM7A 2B49A 1XXPA 3BRHA 1X24A 2NV5A 2M3VA 3CM3A 5KA2A 4I8NA 3O4SA 2F46A 2HVLA 1XBOA 5KA7A 1I9SA 3QCKA 3S3KA 2BIJA 2I1YA 1E8CA 3V0EA 4RH5A 3I7ZA 3V0IA 2F6TA 2F6VA 1C88A 2VEWA 4OHHA 2I4EA 4QBWA 2QCTA 3NRSA 3QKQA 1ZZWA 1C85A 4DGXA 2HC2A 1NL9A 2G59A 2NTAA 2F00A 1PH0A 2QCJA 2AM2A 4KI9A 2B4PA 4RH9A 1BZJA 2VTDA 4JBCA 3S4OA 3S4EA 3V0JA 1XXVA 2VOSA 3M4UA 2FH7A 2Y67A 5KACA 1Q6SA 2J16B 2B07A 5LXQB 1YZ4A 4RKKA 4H34A 3I80A 1YTNA 1YTSA 3O3LA 1GQQA 1P31A 1FGSA 3O5XA 2CM8A 2I3UA 2I75A 2J16A 5KA4A 1OETA 2B4UA 4BJOA 5KA8A 3QCIA 2HNQA 5KA0A 3QCBA 2HC1A 2I4GA 4KYRA 3QCMA 4YR8B 1KAVA 1V3AA 4OHLA 3A5KA 5EHRA 1E0DA 4WU2A 1YGUA 1L8GA 2DXPA 3AWGA 4AZ1A 3QCCA 1R6HA 1AAXA 2CMBA 3BLTA 1YTWA 3O4UA 2CNHA 3EB1A 1WCHA 2I5XA 4PYHA 4GFVA 4ZRTA 4IKCA 1PTVA 1NWEA 3OLRA 4BPCA 5BZXA 1EEOA 5KA9A 4RDDA 2PI7A 3N0AA 3O4TA 3LJ8A 1Q6NA 2AZRA 2CNGA 4WU3A 5KA1A 3I36A 1PTTA 1Q1MA 1I57A 1GG4A 2H4GA 1J4XA 2QBPA 2P6XA 3D42A 3QCNA 2WJPA 3V0FA 2Q47A 3F81A 2OZ5A 1O5ZA 3OMHA 2GC6A 1VHRA 2VEYA 5KADA 2I6JA 2GJTA 2NT2A 3QCZA 2I6IA 4NNDA 2CMCA 4R0TA 1G7GA 3QCHA 1OEOX 2CNFA 5I6VA 4YAAA 3A5JA 1OEVA 2I6PA 4QDIA 3MVNA 4ZI4A 2Y68A 2PA5A 2I4HA 5BX1A 3F99A 1I9TA 1G4US 2HY3A 3HN7A 5K24A 3RO1A 3ZMPA 2PT0A 4NWGA 1GFYA 1OHEA 2JFGA 1P15A 2QBSA 3F41A 2I6MA 2OOQA 1G1GA 3S3FA 2UUPA 1JBWA 1C86A 3PS5A 2H4KA 2F71A 2Y2FA 1A5YA 3V0DA 3SMEA 1WAXA 2PBNA 1LQFA 3ZV2A 4MBBA 3RZ2A 2VEVA 2BV5A 2PSZA 1W78A 3ZM5A 1C84A 2H02A 2P4DA 1ONYA 5K9VA 5BZZA 2WGPA 2FJNA 3ZL8A 5J8RA 3QCEA 1RPMA 2CJZA 3MOWA 1BZCA 1YFOA 2NLKA 1XRIA 4QF5A 4ERCA 3ZM2A 3B7OA 4R30A 2CNEA 1SUGA 4D3QA 2JFHA 2B3OA 1OESA 5AWXA 2QDPA 3GXHA 4Z6BA 1PTYA 2JJDA 1MKPA 1RXDA 1T49A 3ZM0A 3EMUA 2UUOA 4HJPA 5A5EA 2FJMA 2AM1A 1Q6JA 2ZN7A 1U25A 2J17A 3D44A 4Y2EA 1QZ0A 4QAPA 2F6YA 1NWLA 3S3HA 1QXKA 4HRFA 2OC3A 3F9BA 1D5RA 2I3RA 1LYVA 4GE5A 4S0GA 3BLUA 4ZIYA 1JBVA 3EAXA 2WTZA 2VTEA 3U96A 5KA3A 4UAGA 4BUCA 2RF6A 4CVMA 5MMZB 4QUNA 1UAGA 2F70A 2CNIA 4KYQA 1M3GA 2QEPA 2C7SA 1U24A 2R0BA 4R0SA 1FPZA 2A3KA 1NNYA 2NZ6A 1PA9A 2VEUA 1Q6TA 2CFVA 3PYZA 3QCGA 4NX8A 3LK7A 1YPTA 4OHEA 3QKPA 3UAGA 1BZHA 1G7FA 5A5FA 2B4OA 4D3RA 3QCLA 3QCJA 4RHGA 2F6WA 1C87A 5HDEA 1YGRA 1FPRA 2G6ZA 3D1HA 5EHPA 3MOZA 4GRZA 2F6ZA 4OHDA 1W7KA 2BZLA 2ZMMA 4TVVA 1EENA 4HV4A 2I6OA 1ONZA 4WTYA 5K22A 1WRMA 4QAHA 4OHIA 1PXHA 4J51A 4PVGA 2H03A 4DGPA 1L8KA 4GFUA 4C13A 2AHSA 2OUDA 2E0TA 1PTUA 1OHCA 2VORA 1XM2A 1GQYA 4B04A 2CMAA 2C46A 2CM3A 4CVKA 2HCMA 2XPCA 2GCBA 4RI4A 4ICZA 2QBQA 4GRYA 1YWFA 2QDCA 1U26A 2XJAA 2CM2A 4GE2A 1NZ7A 2H4VA 1FQ1A 1ZC0A 3QCDA 2Q05A 1PA1A 3RGOA 1JLNA 4HJQA 2ESBA 5BUGA 5KABA 4D3PA 4H1OA 1OEUA 3NMEA 5IBSA 2YDUA 3AWEA 1KAKA 2Y66A 1Q6PA 1G1HA 1ZCLA 3V0GA 3N2AA 3V0HA 3ZM3A 2Y96A 2HXPA 4QBEA 4Y14A 2GCAA 1EEHA 2A8BA 1YN9A 1J6UA 2IMGA 4JNBA 5K25A 2QBRA 2Y1OA 3GXGA 3EZZA 1NO6A 2JFFA 1OEMX 1Q6MA 1GWZA 5K9WA 5GTJA 4QUMA 1ZCKA 2SHPA 3D1QA 3ZM1A 5M43A 4NYHA 2GWOA 3ZM6A 1JF7A 1ECVA 4ZN5A 1P3DA 4JMJA 2H04A 1T48A 2QDMA 2F6FA 2GC5A 4JMKA 3MMJA 3RGQA 2BGDA 4RI5A 3D1OA 4CVLA 5KAAA
chains in the Genus database with same CATH topology
3AWFA 1C83A 3QCFA 4GWFA 1LARA 2I42A 1G1FA 1G4WR 4GE6A 3EU0A 5IBMA 1PYNA 1T4JA 2VEXA 2GP0A 2MBCA 3BM8A 4WOHA 2PQ5A 2HB1A 1OHDA 4GS0A 3CWEA 3SR9A 2B4SA 2NT7A 3F9AA 4NWFA 3S3EA 3ZMQA 5K23A 3H2XA 2BGEA 3D9CA 2HNPA 2CM7A 2B49A 1XXPA 3BRHA 1X24A 2NV5A 2M3VA 3CM3A 5KA2A 4I8NA 3O4SA 2F46A 2HVLA 1XBOA 5KA7A 1I9SA 3QCKA 3S3KA 2BIJA 2I1YA 3V0EA 4RH5A 3I7ZA 3V0IA 2F6TA 2F6VA 1C88A 2VEWA 4OHHA 2I4EA 4QBWA 2QCTA 3QKQA 1ZZWA 1C85A 4DGXA 2HC2A 1NL9A 2G59A 2NTAA 1PH0A 2QCJA 4KI9A 2B4PA 4RH9A 1BZJA 4JBCA 3S4OA 3S4EA 3V0JA 1XXVA 3M4UA 2FH7A 5KACA 1Q6SA 2J16B 2B07A 5LXQB 1YZ4A 4RKKA 4H34A 3I80A 1YTNA 1YTSA 3O3LA 3O5XA 2CM8A 2I3UA 2I75A 2J16A 5KA4A 1OETA 2B4UA 4BJOA 5KA8A 3QCIA 2HNQA 5KA0A 3QCBA 2HC1A 2I4GA 4KYRA 3QCMA 4YR8B 1KAVA 1V3AA 4OHLA 3A5KA 5EHRA 4WU2A 1YGUA 1L8GA 2DXPA 3AWGA 4AZ1A 3QCCA 1R6HA 1AAXA 2CMBA 3BLTA 1YTWA 3O4UA 2CNHA 3EB1A 1WCHA 2I5XA 4PYHA 4GFVA 4ZRTA 4IKCA 1PTVA 1NWEA 3OLRA 4BPCA 5BZXA 1EEOA 5KA9A 4RDDA 2PI7A 3N0AA 3O4TA 3LJ8A 1Q6NA 2AZRA 2CNGA 4WU3A 5KA1A 3I36A 1PTTA 1Q1MA 1I57A 2H4GA 1J4XA 2QBPA 2P6XA 3D42A 3QCNA 3V0FA 2Q47A 3F81A 2OZ5A 3OMHA 1VHRA 2VEYA 5KADA 2I6JA 2GJTA 2NT2A 2I6IA 4NNDA 2CMCA 4R0TA 1G7GA 3QCHA 1OEOX 2CNFA 5I6VA 4YAAA 3A5JA 1OEVA 2I6PA 4ZI4A 2PA5A 2I4HA 5BX1A 3F99A 1I9TA 1G4US 2HY3A 5K24A 3RO1A 3ZMPA 2PT0A 4NWGA 1GFYA 1OHEA 1P15A 2QBSA 3F41A 2I6MA 2OOQA 1G1GA 3S3FA 1C86A 3PS5A 2H4KA 2F71A 2Y2FA 1A5YA 3V0DA 3SMEA 1WAXA 2PBNA 1LQFA 3ZV2A 4MBBA 3RZ2A 2VEVA 2BV5A 2PSZA 1C84A 2H02A 2P4DA 1ONYA 5K9VA 5BZZA 2WGPA 2FJNA 5J8RA 3QCEA 1RPMA 2CJZA 3MOWA 1BZCA 1YFOA 2NLKA 1XRIA 4ERCA 3ZM2A 3B7OA 4R30A 2CNEA 1SUGA 4D3QA 2B3OA 1OESA 5AWXA 2QDPA 3GXHA 4Z6BA 1PTYA 2JJDA 1MKPA 1RXDA 1T49A 3ZM0A 3EMUA 4HJPA 2FJMA 1Q6JA 2ZN7A 1U25A 2J17A 3D44A 4Y2EA 1QZ0A 4QAPA 2F6YA 1NWLA 3S3HA 1QXKA 4HRFA 2OC3A 3F9BA 1D5RA 2I3RA 1LYVA 4GE5A 4S0GA 3BLUA 3EAXA 3U96A 5KA3A 2RF6A 5MMZB 4QUNA 2F70A 2CNIA 4KYQA 1M3GA 2QEPA 2C7SA 1U24A 2R0BA 4R0SA 1FPZA 2A3KA 1NNYA 2NZ6A 1PA9A 2VEUA 1Q6TA 2CFVA 3QCGA 4NX8A 1YPTA 4OHEA 3QKPA 1BZHA 1G7FA 2B4OA 4D3RA 3QCLA 3QCJA 4RHGA 2F6WA 1C87A 5HDEA 1YGRA 1FPRA 2G6ZA 3D1HA 5EHPA 3MOZA 4GRZA 2F6ZA 4OHDA 2BZLA 2ZMMA 4TVVA 1EENA 2I6OA 1ONZA 4WTYA 5K22A 1WRMA 4QAHA 4OHIA 1PXHA 4J51A 4PVGA 2H03A 4DGPA 1L8KA 4GFUA 2AHSA 2OUDA 2E0TA 1PTUA 1OHCA 1XM2A 4B04A 2CMAA 2C46A 2CM3A 2HCMA 4RI4A 4ICZA 2QBQA 4GRYA 1YWFA 2QDCA 1U26A 4GE2A 2CM2A 1NZ7A 2H4VA 1FQ1A 1ZC0A 3QCDA 2Q05A 1PA1A 3RGOA 1JLNA 4HJQA 2ESBA 5BUGA 5KABA 4D3PA 4H1OA 1OEUA 3NMEA 5IBSA 2YDUA 3AWEA 1KAKA 1Q6PA 1G1HA 1ZCLA 3V0GA 3V0HA 3ZM3A 2Y96A 2HXPA 4QBEA 4Y14A 2A8BA 1YN9A 2IMGA 4JNBA 5K25A 2QBRA 3GXGA 3EZZA 1NO6A 1OEMX 1Q6MA 1GWZA 5K9WA 5GTJA 4QUMA 1ZCKA 2SHPA 3D1QA 3ZM1A 5M43A 4NYHA 2GWOA 1JF7A 1ECVA 4ZN5A 4JMJA 2H04A 1T48A 2QDMA 2F6FA 4JMKA 3MMJA 3RGQA 2BGDA 4RI5A 3D1OA 5KAAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWF A;  1C83 A;  3QCF A;  4GWF A;  1LAR A;  2I42 A;  1G1F A;  1G4W R;  4GE6 A;  3EU0 A;  5IBM A;  1PYN A;  1T4J A;  2VEX A;  2GP0 A;  2MBC A;  3BM8 A;  4WOH A;  2PQ5 A;  2HB1 A;  1OHD A;  4GS0 A;  3CWE A;  3SR9 A;  2B4S A;  2NT7 A;  3F9A A;  4NWF A;  3S3E A;  3ZMQ A;  5K23 A;  3H2X A;  2BGE A;  3D9C A;  2HNP A;  2CM7 A;  2B49 A;  1XXP A;  3BRH A;  1X24 A;  2NV5 A;  2M3V A;  3CM3 A;  5KA2 A;  4I8N A;  3O4S A;  2F46 A;  2HVL A;  1XBO A;  5KA7 A;  1I9S A;  3QCK A;  3S3K A;  2BIJ A;  2I1Y A;  3V0E A;  4RH5 A;  3I7Z A;  3V0I A;  2F6T A;  2F6V A;  1C88 A;  2VEW A;  4OHH A;  2I4E A;  4QBW A;  2QCT A;  3QKQ A;  1ZZW A;  1C85 A;  4DGX A;  2HC2 A;  1NL9 A;  2G59 A;  2NTA A;  1PH0 A;  2QCJ A;  4KI9 A;  2B4P A;  4RH9 A;  1BZJ A;  4JBC A;  3S4O A;  3S4E A;  3V0J A;  1XXV A;  3M4U A;  2FH7 A;  5KAC A;  1Q6S A;  2J16 B;  2B07 A;  5LXQ B;  1YZ4 A;  4RKK A;  4H34 A;  3I80 A;  1YTN A;  1YTS A;  3O3L A;  3O5X A;  2CM8 A;  2I3U A;  2I75 A;  2J16 A;  5KA4 A;  1OET A;  2B4U A;  4BJO A;  5KA8 A;  3QCI A;  2HNQ A;  5KA0 A;  3QCB A;  2HC1 A;  2I4G A;  4KYR A;  3QCM A;  4YR8 B;  1KAV A;  1V3A A;  4OHL A;  3A5K A;  5EHR A;  4WU2 A;  1YGU A;  1L8G A;  2DXP A;  3AWG A;  4AZ1 A;  3QCC A;  1R6H A;  1AAX A;  2CMB A;  3BLT A;  1YTW A;  3O4U A;  2CNH A;  3EB1 A;  1WCH A;  2I5X A;  4PYH A;  4GFV A;  4ZRT A;  4IKC A;  1PTV A;  1NWE A;  3OLR A;  4BPC A;  5BZX A;  1EEO A;  5KA9 A;  4RDD A;  2PI7 A;  3N0A A;  3O4T A;  3LJ8 A;  1Q6N A;  2AZR A;  2CNG A;  4WU3 A;  5KA1 A;  3I36 A;  1PTT A;  1Q1M A;  1I57 A;  2H4G A;  1J4X A;  2QBP A;  2P6X A;  3D42 A;  3QCN A;  3V0F A;  2Q47 A;  3F81 A;  2OZ5 A;  3OMH A;  1VHR A;  2VEY A;  5KAD A;  2I6J A;  2GJT A;  2NT2 A;  2I6I A;  4NND A;  2CMC A;  4R0T A;  1G7G A;  3QCH A;  1OEO X;  2CNF A;  5I6V A;  4YAA A;  3A5J A;  1OEV A;  2I6P A;  4ZI4 A;  2PA5 A;  2I4H A;  5BX1 A;  3F99 A;  1I9T A;  1G4U S;  2HY3 A;  5K24 A;  3RO1 A;  3ZMP A;  2PT0 A;  4NWG A;  1GFY A;  1OHE A;  1P15 A;  2QBS A;  3F41 A;  2I6M A;  2OOQ A;  1G1G A;  3S3F A;  1C86 A;  3PS5 A;  2H4K A;  2F71 A;  2Y2F A;  1A5Y A;  3V0D A;  3SME A;  1WAX A;  2PBN A;  1LQF A;  3ZV2 A;  4MBB A;  3RZ2 A;  2VEV A;  2BV5 A;  2PSZ A;  1C84 A;  2H02 A;  2P4D A;  1ONY A;  5K9V A;  5BZZ A;  2WGP A;  2FJN A;  5J8R A;  3QCE A;  1RPM A;  2CJZ A;  3MOW A;  1BZC A;  1YFO A;  2NLK A;  1XRI A;  4ERC A;  3ZM2 A;  3B7O A;  4R30 A;  2CNE A;  1SUG A;  4D3Q A;  2B3O A;  1OES A;  5AWX A;  2QDP A;  3GXH A;  4Z6B A;  1PTY A;  2JJD A;  1MKP A;  1RXD A;  1T49 A;  3ZM0 A;  3EMU A;  4HJP A;  2FJM A;  1Q6J A;  2ZN7 A;  1U25 A;  2J17 A;  3D44 A;  4Y2E A;  1QZ0 A;  4QAP A;  2F6Y A;  1NWL A;  3S3H A;  1QXK A;  4HRF A;  2OC3 A;  3F9B A;  1D5R A;  2I3R A;  1LYV A;  4GE5 A;  4S0G A;  3BLU A;  3EAX A;  3U96 A;  5KA3 A;  2RF6 A;  5MMZ B;  4QUN A;  2F70 A;  2CNI A;  4KYQ A;  1M3G A;  2QEP A;  2C7S A;  1U24 A;  2R0B A;  4R0S A;  1FPZ A;  2A3K A;  1NNY A;  2NZ6 A;  1PA9 A;  2VEU A;  1Q6T A;  2CFV A;  3QCG A;  4NX8 A;  1YPT A;  4OHE A;  3QKP A;  1BZH A;  1G7F A;  2B4O A;  4D3R A;  3QCL A;  3QCJ A;  4RHG A;  2F6W A;  1C87 A;  5HDE A;  1YGR A;  1FPR A;  2G6Z A;  3D1H A;  5EHP A;  3MOZ A;  4GRZ A;  2F6Z A;  4OHD A;  2BZL A;  2ZMM A;  4TVV A;  1EEN A;  2I6O A;  1ONZ A;  4WTY A;  5K22 A;  1WRM A;  4QAH A;  4OHI A;  1PXH A;  4J51 A;  4PVG A;  2H03 A;  4DGP A;  1L8K A;  4GFU A;  2AHS A;  2OUD A;  2E0T A;  1PTU A;  1OHC A;  1XM2 A;  4B04 A;  2CMA A;  2C46 A;  2CM3 A;  2HCM A;  4RI4 A;  4ICZ A;  2QBQ A;  4GRY A;  1YWF A;  2QDC A;  1U26 A;  4GE2 A;  2CM2 A;  1NZ7 A;  2H4V A;  1FQ1 A;  1ZC0 A;  3QCD A;  2Q05 A;  1PA1 A;  3RGO A;  1JLN A;  4HJQ A;  2ESB A;  5BUG A;  5KAB A;  4D3P A;  4H1O A;  1OEU A;  3NME A;  5IBS A;  2YDU A;  3AWE A;  1KAK A;  1Q6P A;  1G1H A;  1ZCL A;  3V0G A;  3V0H A;  3ZM3 A;  2Y96 A;  2HXP A;  4QBE A;  4Y14 A;  2A8B A;  1YN9 A;  2IMG A;  4JNB A;  5K25 A;  2QBR A;  3GXG A;  3EZZ A;  1NO6 A;  1OEM X;  1Q6M A;  1GWZ A;  5K9W A;  5GTJ A;  4QUM A;  1ZCK A;  2SHP A;  3D1Q A;  3ZM1 A;  5M43 A;  4NYH A;  2GWO A;  1JF7 A;  1ECV A;  4ZN5 A;  4JMJ A;  2H04 A;  1T48 A;  2QDM A;  2F6F A;  4JMK A;  3MMJ A;  3RGQ A;  2BGD A;  4RI5 A;  3D1O A;  5KAA A; 
#chains in the Genus database with same CATH topology
 3AWF A;  1C83 A;  3QCF A;  4BUB A;  4GWF A;  1LAR A;  2I42 A;  1G1F A;  1G4W R;  4GE6 A;  3EU0 A;  5IBM A;  1PYN A;  1T4J A;  2VEX A;  2GP0 A;  2MBC A;  3BM8 A;  4WOH A;  2PQ5 A;  2HB1 A;  1OHD A;  4GS0 A;  3CWE A;  3SR9 A;  2B4S A;  2NT7 A;  2X5O A;  3F9A A;  4NWF A;  3S3E A;  3ZMQ A;  5K23 A;  2UAG A;  3H2X A;  2BGE A;  4C12 A;  3D9C A;  2HNP A;  2CM7 A;  2B49 A;  1XXP A;  3BRH A;  1X24 A;  2NV5 A;  2M3V A;  3CM3 A;  5KA2 A;  4I8N A;  3O4S A;  2F46 A;  2HVL A;  1XBO A;  5KA7 A;  1I9S A;  3QCK A;  3S3K A;  2BIJ A;  2I1Y A;  1E8C A;  3V0E A;  4RH5 A;  3I7Z A;  3V0I A;  2F6T A;  2F6V A;  1C88 A;  2VEW A;  4OHH A;  2I4E A;  4QBW A;  2QCT A;  3NRS A;  3QKQ A;  1ZZW A;  1C85 A;  4DGX A;  2HC2 A;  1NL9 A;  2G59 A;  2NTA A;  2F00 A;  1PH0 A;  2QCJ A;  2AM2 A;  4KI9 A;  2B4P A;  4RH9 A;  1BZJ A;  2VTD A;  4JBC A;  3S4O A;  3S4E A;  3V0J A;  1XXV A;  2VOS A;  3M4U A;  2FH7 A;  2Y67 A;  5KAC A;  1Q6S A;  2J16 B;  2B07 A;  5LXQ B;  1YZ4 A;  4RKK A;  4H34 A;  3I80 A;  1YTN A;  1YTS A;  3O3L A;  1GQQ A;  1P31 A;  1FGS A;  3O5X A;  2CM8 A;  2I3U A;  2I75 A;  2J16 A;  5KA4 A;  1OET A;  2B4U A;  4BJO A;  5KA8 A;  3QCI A;  2HNQ A;  5KA0 A;  3QCB A;  2HC1 A;  2I4G A;  4KYR A;  3QCM A;  4YR8 B;  1KAV A;  1V3A A;  4OHL A;  3A5K A;  5EHR A;  1E0D A;  4WU2 A;  1YGU A;  1L8G A;  2DXP A;  3AWG A;  4AZ1 A;  3QCC A;  1R6H A;  1AAX A;  2CMB A;  3BLT A;  1YTW A;  3O4U A;  2CNH A;  3EB1 A;  1WCH A;  2I5X A;  4PYH A;  4GFV A;  4ZRT A;  4IKC A;  1PTV A;  1NWE A;  3OLR A;  4BPC A;  5BZX A;  1EEO A;  5KA9 A;  4RDD A;  2PI7 A;  3N0A A;  3O4T A;  3LJ8 A;  1Q6N A;  2AZR A;  2CNG A;  4WU3 A;  5KA1 A;  3I36 A;  1PTT A;  1Q1M A;  1I57 A;  1GG4 A;  2H4G A;  1J4X A;  2QBP A;  2P6X A;  3D42 A;  3QCN A;  2WJP A;  3V0F A;  2Q47 A;  3F81 A;  2OZ5 A;  1O5Z A;  3OMH A;  2GC6 A;  1VHR A;  2VEY A;  5KAD A;  2I6J A;  2GJT A;  2NT2 A;  3QCZ A;  2I6I A;  4NND A;  2CMC A;  4R0T A;  1G7G A;  3QCH A;  1OEO X;  2CNF A;  5I6V A;  4YAA A;  3A5J A;  1OEV A;  2I6P A;  4QDI A;  3MVN A;  4ZI4 A;  2Y68 A;  2PA5 A;  2I4H A;  5BX1 A;  3F99 A;  1I9T A;  1G4U S;  2HY3 A;  3HN7 A;  5K24 A;  3RO1 A;  3ZMP A;  2PT0 A;  4NWG A;  1GFY A;  1OHE A;  2JFG A;  1P15 A;  2QBS A;  3F41 A;  2I6M A;  2OOQ A;  1G1G A;  3S3F A;  2UUP A;  1JBW A;  1C86 A;  3PS5 A;  2H4K A;  2F71 A;  2Y2F A;  1A5Y A;  3V0D A;  3SME A;  1WAX A;  2PBN A;  1LQF A;  3ZV2 A;  4MBB A;  3RZ2 A;  2VEV A;  2BV5 A;  2PSZ A;  1W78 A;  3ZM5 A;  1C84 A;  2H02 A;  2P4D A;  1ONY A;  5K9V A;  5BZZ A;  2WGP A;  2FJN A;  3ZL8 A;  5J8R A;  3QCE A;  1RPM A;  2CJZ A;  3MOW A;  1BZC A;  1YFO A;  2NLK A;  1XRI A;  4QF5 A;  4ERC A;  3ZM2 A;  3B7O A;  4R30 A;  2CNE A;  1SUG A;  4D3Q A;  2JFH A;  2B3O A;  1OES A;  5AWX A;  2QDP A;  3GXH A;  4Z6B A;  1PTY A;  2JJD A;  1MKP A;  1RXD A;  1T49 A;  3ZM0 A;  3EMU A;  2UUO A;  4HJP A;  5A5E A;  2FJM A;  2AM1 A;  1Q6J A;  2ZN7 A;  1U25 A;  2J17 A;  3D44 A;  4Y2E A;  1QZ0 A;  4QAP A;  2F6Y A;  1NWL A;  3S3H A;  1QXK A;  4HRF A;  2OC3 A;  3F9B A;  1D5R A;  2I3R A;  1LYV A;  4GE5 A;  4S0G A;  3BLU A;  4ZIY A;  1JBV A;  3EAX A;  2WTZ A;  2VTE A;  3U96 A;  5KA3 A;  4UAG A;  4BUC A;  2RF6 A;  4CVM A;  5MMZ B;  4QUN A;  1UAG A;  2F70 A;  2CNI A;  4KYQ A;  1M3G A;  2QEP A;  2C7S A;  1U24 A;  2R0B A;  4R0S A;  1FPZ A;  2A3K A;  1NNY A;  2NZ6 A;  1PA9 A;  2VEU A;  1Q6T A;  2CFV A;  3PYZ A;  3QCG A;  4NX8 A;  3LK7 A;  1YPT A;  4OHE A;  3QKP A;  3UAG A;  1BZH A;  1G7F A;  5A5F A;  2B4O A;  4D3R A;  3QCL A;  3QCJ A;  4RHG A;  2F6W A;  1C87 A;  5HDE A;  1YGR A;  1FPR A;  2G6Z A;  3D1H A;  5EHP A;  3MOZ A;  4GRZ A;  2F6Z A;  4OHD A;  1W7K A;  2BZL A;  2ZMM A;  4TVV A;  1EEN A;  4HV4 A;  2I6O A;  1ONZ A;  4WTY A;  5K22 A;  1WRM A;  4QAH A;  4OHI A;  1PXH A;  4J51 A;  4PVG A;  2H03 A;  4DGP A;  1L8K A;  4GFU A;  4C13 A;  2AHS A;  2OUD A;  2E0T A;  1PTU A;  1OHC A;  2VOR A;  1XM2 A;  1GQY A;  4B04 A;  2CMA A;  2C46 A;  2CM3 A;  4CVK A;  2HCM A;  2XPC A;  2GCB A;  4RI4 A;  4ICZ A;  2QBQ A;  4GRY A;  1YWF A;  2QDC A;  1U26 A;  2XJA A;  2CM2 A;  4GE2 A;  1NZ7 A;  2H4V A;  1FQ1 A;  1ZC0 A;  3QCD A;  2Q05 A;  1PA1 A;  3RGO A;  1JLN A;  4HJQ A;  2ESB A;  5BUG A;  5KAB A;  4D3P A;  4H1O A;  1OEU A;  3NME A;  5IBS A;  2YDU A;  3AWE A;  1KAK A;  2Y66 A;  1Q6P A;  1G1H A;  1ZCL A;  3V0G A;  3N2A A;  3V0H A;  3ZM3 A;  2Y96 A;  2HXP A;  4QBE A;  4Y14 A;  2GCA A;  1EEH A;  2A8B A;  1YN9 A;  1J6U A;  2IMG A;  4JNB A;  5K25 A;  2QBR A;  2Y1O A;  3GXG A;  3EZZ A;  1NO6 A;  2JFF A;  1OEM X;  1Q6M A;  1GWZ A;  5K9W A;  5GTJ A;  4QUM A;  1ZCK A;  2SHP A;  3D1Q A;  3ZM1 A;  5M43 A;  4NYH A;  2GWO A;  3ZM6 A;  1JF7 A;  1ECV A;  4ZN5 A;  1P3D A;  4JMJ A;  2H04 A;  1T48 A;  2QDM A;  2F6F A;  2GC5 A;  4JMK A;  3MMJ A;  3RGQ A;  2BGD A;  4RI5 A;  3D1O A;  4CVL A;  5KAA A; 
#chains in the Genus database with same CATH homology
 3AWF A;  1C83 A;  3QCF A;  4GWF A;  1LAR A;  2I42 A;  1G1F A;  1G4W R;  4GE6 A;  3EU0 A;  5IBM A;  1PYN A;  1T4J A;  2VEX A;  2GP0 A;  2MBC A;  3BM8 A;  4WOH A;  2PQ5 A;  2HB1 A;  1OHD A;  4GS0 A;  3CWE A;  3SR9 A;  2B4S A;  2NT7 A;  3F9A A;  4NWF A;  3S3E A;  3ZMQ A;  5K23 A;  3H2X A;  2BGE A;  3D9C A;  2HNP A;  2CM7 A;  2B49 A;  1XXP A;  3BRH A;  1X24 A;  2NV5 A;  2M3V A;  3CM3 A;  5KA2 A;  4I8N A;  3O4S A;  2F46 A;  2HVL A;  1XBO A;  5KA7 A;  1I9S A;  3QCK A;  3S3K A;  2BIJ A;  2I1Y A;  3V0E A;  4RH5 A;  3I7Z A;  3V0I A;  2F6T A;  2F6V A;  1C88 A;  2VEW A;  4OHH A;  2I4E A;  4QBW A;  2QCT A;  3QKQ A;  1ZZW A;  1C85 A;  4DGX A;  2HC2 A;  1NL9 A;  2G59 A;  2NTA A;  1PH0 A;  2QCJ A;  4KI9 A;  2B4P A;  4RH9 A;  1BZJ A;  4JBC A;  3S4O A;  3S4E A;  3V0J A;  1XXV A;  3M4U A;  2FH7 A;  5KAC A;  1Q6S A;  2J16 B;  2B07 A;  5LXQ B;  1YZ4 A;  4RKK A;  4H34 A;  3I80 A;  1YTN A;  1YTS A;  3O3L A;  3O5X A;  2CM8 A;  2I3U A;  2I75 A;  2J16 A;  5KA4 A;  1OET A;  2B4U A;  4BJO A;  5KA8 A;  3QCI A;  2HNQ A;  5KA0 A;  3QCB A;  2HC1 A;  2I4G A;  4KYR A;  3QCM A;  4YR8 B;  1KAV A;  1V3A A;  4OHL A;  3A5K A;  5EHR A;  4WU2 A;  1YGU A;  1L8G A;  2DXP A;  3AWG A;  4AZ1 A;  3QCC A;  1R6H A;  1AAX A;  2CMB A;  3BLT A;  1YTW A;  3O4U A;  2CNH A;  3EB1 A;  1WCH A;  2I5X A;  4PYH A;  4GFV A;  4ZRT A;  4IKC A;  1PTV A;  1NWE A;  3OLR A;  4BPC A;  5BZX A;  1EEO A;  5KA9 A;  4RDD A;  2PI7 A;  3N0A A;  3O4T A;  3LJ8 A;  1Q6N A;  2AZR A;  2CNG A;  4WU3 A;  5KA1 A;  3I36 A;  1PTT A;  1Q1M A;  1I57 A;  2H4G A;  1J4X A;  2QBP A;  2P6X A;  3D42 A;  3QCN A;  3V0F A;  2Q47 A;  3F81 A;  2OZ5 A;  3OMH A;  1VHR A;  2VEY A;  5KAD A;  2I6J A;  2GJT A;  2NT2 A;  2I6I A;  4NND A;  2CMC A;  4R0T A;  1G7G A;  3QCH A;  1OEO X;  2CNF A;  5I6V A;  4YAA A;  3A5J A;  1OEV A;  2I6P A;  4ZI4 A;  2PA5 A;  2I4H A;  5BX1 A;  3F99 A;  1I9T A;  1G4U S;  2HY3 A;  5K24 A;  3RO1 A;  3ZMP A;  2PT0 A;  4NWG A;  1GFY A;  1OHE A;  1P15 A;  2QBS A;  3F41 A;  2I6M A;  2OOQ A;  1G1G A;  3S3F A;  1C86 A;  3PS5 A;  2H4K A;  2F71 A;  2Y2F A;  1A5Y A;  3V0D A;  3SME A;  1WAX A;  2PBN A;  1LQF A;  3ZV2 A;  4MBB A;  3RZ2 A;  2VEV A;  2BV5 A;  2PSZ A;  1C84 A;  2H02 A;  2P4D A;  1ONY A;  5K9V A;  5BZZ A;  2WGP A;  2FJN A;  5J8R A;  3QCE A;  1RPM A;  2CJZ A;  3MOW A;  1BZC A;  1YFO A;  2NLK A;  1XRI A;  4ERC A;  3ZM2 A;  3B7O A;  4R30 A;  2CNE A;  1SUG A;  4D3Q A;  2B3O A;  1OES A;  5AWX A;  2QDP A;  3GXH A;  4Z6B A;  1PTY A;  2JJD A;  1MKP A;  1RXD A;  1T49 A;  3ZM0 A;  3EMU A;  4HJP A;  2FJM A;  1Q6J A;  2ZN7 A;  1U25 A;  2J17 A;  3D44 A;  4Y2E A;  1QZ0 A;  4QAP A;  2F6Y A;  1NWL A;  3S3H A;  1QXK A;  4HRF A;  2OC3 A;  3F9B A;  1D5R A;  2I3R A;  1LYV A;  4GE5 A;  4S0G A;  3BLU A;  3EAX A;  3U96 A;  5KA3 A;  2RF6 A;  5MMZ B;  4QUN A;  2F70 A;  2CNI A;  4KYQ A;  1M3G A;  2QEP A;  2C7S A;  1U24 A;  2R0B A;  4R0S A;  1FPZ A;  2A3K A;  1NNY A;  2NZ6 A;  1PA9 A;  2VEU A;  1Q6T A;  2CFV A;  3QCG A;  4NX8 A;  1YPT A;  4OHE A;  3QKP A;  1BZH A;  1G7F A;  2B4O A;  4D3R A;  3QCL A;  3QCJ A;  4RHG A;  2F6W A;  1C87 A;  5HDE A;  1YGR A;  1FPR A;  2G6Z A;  3D1H A;  5EHP A;  3MOZ A;  4GRZ A;  2F6Z A;  4OHD A;  2BZL A;  2ZMM A;  4TVV A;  1EEN A;  2I6O A;  1ONZ A;  4WTY A;  5K22 A;  1WRM A;  4QAH A;  4OHI A;  1PXH A;  4J51 A;  4PVG A;  2H03 A;  4DGP A;  1L8K A;  4GFU A;  2AHS A;  2OUD A;  2E0T A;  1PTU A;  1OHC A;  1XM2 A;  4B04 A;  2CMA A;  2C46 A;  2CM3 A;  2HCM A;  4RI4 A;  4ICZ A;  2QBQ A;  4GRY A;  1YWF A;  2QDC A;  1U26 A;  4GE2 A;  2CM2 A;  1NZ7 A;  2H4V A;  1FQ1 A;  1ZC0 A;  3QCD A;  2Q05 A;  1PA1 A;  3RGO A;  1JLN A;  4HJQ A;  2ESB A;  5BUG A;  5KAB A;  4D3P A;  4H1O A;  1OEU A;  3NME A;  5IBS A;  2YDU A;  3AWE A;  1KAK A;  1Q6P A;  1G1H A;  1ZCL A;  3V0G A;  3V0H A;  3ZM3 A;  2Y96 A;  2HXP A;  4QBE A;  4Y14 A;  2A8B A;  1YN9 A;  2IMG A;  4JNB A;  5K25 A;  2QBR A;  3GXG A;  3EZZ A;  1NO6 A;  1OEM X;  1Q6M A;  1GWZ A;  5K9W A;  5GTJ A;  4QUM A;  1ZCK A;  2SHP A;  3D1Q A;  3ZM1 A;  5M43 A;  4NYH A;  2GWO A;  1JF7 A;  1ECV A;  4ZN5 A;  4JMJ A;  2H04 A;  1T48 A;  2QDM A;  2F6F A;  4JMK A;  3MMJ A;  3RGQ A;  2BGD A;  4RI5 A;  3D1O A;  5KAA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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