2VEXA

Crystal strucutre of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
297
structure length
297
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Isothiazolidinone Inhibitors of Ptp1B Containing Imidazoles and Imidazolines
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 100
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2vexA00
2P6XA 2I6JA 3RGOA 1KAKA 4HJPA 4RDDA 1RXDA 2BIJA 3QCDA 3V0IA 3MMJA 1T48A 2VEYA 4KYRA 2DXPA 3ZM2A 1XM2A 1ZC0A 2MBCA 1Q6TA 1QXKA 4OHDA 1NL9A 1J4XA 3ZMPA 1U26A 1G1HA 1R6HA 2F6FA 2CM2A 1LQFA 1U25A 2I3UA 1U24A 3S4OA 5K22A 2F6WA 1PTTA 1FPZA 3D1QA 3F9BA 3ZM3A 2B49A 3NMEA 3S3EA 4ZRTA 4BPCA 1OHCA 3BM8A 2B4PA 2VEXA 4WU3A 2HB1A 3QCMA 4JBCA 5EHPA 2CNGA 4Z6BA 4I8NA 4R0TA 1G1GA 4D3RA 5KA4A 1AAXA 5KACA 4NNDA 4WU2A 3GXGA 1PH0A 2CMCA 1OEUA 3M4UA 5AWXA 3EAXA 2I4GA 1G1FA 1BZJA 4JMJA 1YZ4A 1L8GA 2CNIA 2PA5A 1FQ1A 4MBBA 1ZZWA 4ERCA 2QBSA 1I57A 2F71A 3EMUA 4OHIA 3V0EA 2I75A 1X24A 2HNPA 5KAAA 2CMBA 3QCIA 1QZ0A 2G6ZA 1P15A 2NLKA 1T49A 1PTYA 1G7FA 2I6MA 1YFOA 3GXHA 2HVLA 1C88A 4GE2A 2CM8A 2FJMA 3I7ZA 5I6VA 3V0DA 1NWLA 4RHGA 3QKPA 5BUGA 4NX8A 3MOZA 2BGEA 3EB1A 2NV5A 1ONYA 2PT0A 3A5JA 3S4EA 1G7GA 4ICZA 2F46A 4Y2EA 2I1YA 3QCCA 5K9VA 2F6TA 2B3OA 2I6PA 2QBQA 1OEVA 3RGQA 2QDPA 4RI5A 2AHSA 5K25A 2IMGA 3QCEA 2JJDA 3F41A 3A5KA 5KA0A 2Y2FA 1OEOX 1LARA 4NWGA 3QCLA 1C87A 1C86A 3N0AA 3O4UA 3O4SA 4RH9A 2ESBA 4PYHA 1ZCLA 2Q05A 2CNHA 2QBRA 2B4SA 4NYHA 2GWOA 1NZ7A 4QUMA 5KA9A 3RO1A 4GE6A 1D5RA 1YTSA 4OHLA 1JF7A 1OHEA 3I36A 4YAAA 5GTJA 1M3GA 1WCHA 4DGPA 3AWEA 5KA8A 1Q6MA 3D42A 4PVGA 3O5XA 2QCJA 2I42A 2PQ5A 1ECVA 3QKQA 2H02A 3AWFA 1SUGA 2GP0A 4GFUA 1A5YA 2VEUA 1KAVA 5KA1A 2PI7A 1BZCA 5KA7A 3EU0A 2FJNA 4WTYA 4HRFA 4QAHA 4KYQA 2I4EA 1Q6SA 3D9CA 5KABA 1RPMA 2GJTA 2QDCA 4AZ1A 2HY3A 1Q6PA 2HCMA 4IKCA 2BV5A 4JMKA 1ZCKA 2VEWA 2NT7A 2R0BA 1GWZA 3V0FA 5KA2A 4QUNA 2WGPA 1XBOA 1OEMX 2CM7A 4Y14A 2F6VA 4DGXA 1XXPA 3BLTA 5MMZB 3ZMQA 4JNBA 4WOHA 2I3RA 2HC2A 5HDEA 3S3HA 4D3QA 2Y96A 3CWEA 1PA9A 2CNFA 3EZZA 1C85A 1XRIA 1OESA 3QCJA 3I80A 4RKKA 1YTNA 4H1OA 1YN9A 2NZ6A 3U96A 2F6ZA 4R0SA 1LYVA 4GS0A 1ONZA 1EEOA 3AWGA 1YPTA 2NTAA 4GRYA 4J51A 3QCHA 4S0GA 1Q6JA 1XXVA 2CMAA 3F9AA 5K24A 3V0GA 2A3KA 1G4WR 5K23A 2E0TA 2QDMA 3V0JA 2M3VA 4NWFA 2FH7A 3QCGA 2OZ5A 1PTUA 3QCKA 1NNYA 2H4VA 4QBWA 1EENA 1YGUA 1PYNA 3BLUA 5BZZA 2AZRA 4HJQA 1C84A 2J16B 1JLNA 2ZN7A 1MKPA 4D3PA 2CJZA 4QBEA 2QCTA 1BZHA 2F70A 3S3FA 2I6IA 2Q47A 3QCBA 3BRHA 2NT2A 5IBSA 2C46A 2RF6A 1YWFA 2HXPA 2H04A 2F6YA 4B04A 1V3AA 2I4HA 5BX1A 2J16A 2CNEA 2OC3A 2BZLA 1Q1MA 2G59A 4RH5A 1C83A 4GFVA 2CM3A 1WAXA 2ZMMA 2BGDA 2HNQA 3CM3A 2I6OA 2YDUA 5KA3A 5EHRA 3D1OA 5K9WA 1I9TA 2P4DA 3H2XA 2I5XA 2H03A 3OMHA 3B7OA 4OHEA 1YTWA 1YGRA 1T4JA 2C7SA 2J17A 2QBPA 4ZN5A 1PA1A 1FPRA 2H4KA 5M43A 3RZ2A 5BZXA 1GFYA 1PTVA 3O3LA 1WRMA 1Q6NA 4KI9A 4GE5A 2PBNA 3D44A 4GWFA 2B4UA 2CFVA 1L8KA 4TVVA 5LXQB 3F81A 4YR8B 4OHHA 2VEVA 5KADA 1I9SA 4R30A 2OOQA 4ZI4A 2PSZA 2B4OA 2HC1A 1NWEA 3F99A 5J8RA 2OUDA 1OHDA 3S3KA 3QCFA 4BJOA 3QCNA 3SR9A 1NO6A 3LJ8A 1G4US 4RI4A 4H34A 3OLRA 2SHPA 2A8BA 5IBMA 3MOWA 3O4TA 1OETA 3PS5A 4GRZA 2B07A 1VHRA 2H4GA 3ZM0A 2QEPA 1PXHA 3V0HA 3ZM1A 3ZV2A 3D1HA 3SMEA 4QAPA
chains in the Genus database with same CATH superfamily
2P6XA 1W78A 2I6JA 3RGOA 1KAKA 1JBWA 4UAGA 4HJPA 4RDDA 1RXDA 2BIJA 3QCDA 3V0IA 3MMJA 1T48A 2VEYA 4KYRA 4CVKA 2DXPA 3ZM2A 1XM2A 1ZC0A 2MBCA 1Q6TA 1QXKA 4OHDA 2Y66A 1NL9A 1J4XA 3ZMPA 2GCBA 1U26A 2VOSA 1G1HA 1R6HA 3ZL8A 2F6FA 2CM2A 1LQFA 1U25A 2I3UA 3PYZA 1U24A 3S4OA 2GCAA 5K22A 2F6WA 1PTTA 1FPZA 3D1QA 3F9BA 3ZM3A 2B49A 3NMEA 3S3EA 4ZRTA 4BPCA 1OHCA 3BM8A 2B4PA 2VEXA 4WU3A 2HB1A 2AM1A 3QCMA 4JBCA 5EHPA 2CNGA 4Z6BA 4I8NA 4R0TA 1G1GA 4D3RA 5KA4A 1AAXA 5KACA 4NNDA 4WU2A 3GXGA 1PH0A 2CMCA 1OEUA 3M4UA 5AWXA 3EAXA 2I4GA 1G1FA 4QF5A 1BZJA 4JMJA 1YZ4A 1L8GA 2CNIA 2PA5A 2WJPA 1FQ1A 3LK7A 4MBBA 1ZZWA 4ERCA 2QBSA 1I57A 2F71A 3EMUA 4OHIA 3V0EA 2I75A 1X24A 2HNPA 5KAAA 2CMBA 3QCIA 1QZ0A 2G6ZA 2JFHA 1P15A 2NLKA 1T49A 1PTYA 1EEHA 1G7FA 2I6MA 1YFOA 3GXHA 2HVLA 1C88A 4GE2A 2CM8A 1UAGA 2FJMA 3I7ZA 5I6VA 3V0DA 1NWLA 4RHGA 3QKPA 5BUGA 4NX8A 2GC6A 3MOZA 2BGEA 3EB1A 4C12A 2NV5A 1ONYA 1E8CA 4BUBA 2PT0A 3A5JA 3S4EA 1G7GA 4ICZA 2F46A 4Y2EA 2Y67A 2I1YA 3QCCA 5K9VA 2F6TA 2B3OA 2I6PA 1O5ZA 2QBQA 1OEVA 3RGQA 2QDPA 4RI5A 2AHSA 5K25A 2UUOA 1JBVA 2IMGA 3QCEA 2JJDA 3F41A 3UAGA 2Y68A 3A5KA 5KA0A 2Y2FA 3QCZA 1P31A 2F00A 1OEOX 1LARA 2VTEA 4NWGA 1C87A 3QCLA 1C86A 3N0AA 1J6UA 3O4UA 3O4SA 4RH9A 2ESBA 4PYHA 4C13A 1ZCLA 2Q05A 2CNHA 2QBRA 2B4SA 4NYHA 2GWOA 1NZ7A 4QUMA 5KA9A 3RO1A 4GE6A 1D5RA 1YTSA 4OHLA 1JF7A 1OHEA 3I36A 4YAAA 5GTJA 1M3GA 2Y1OA 1WCHA 4DGPA 3AWEA 5KA8A 1Q6MA 3D42A 4PVGA 3O5XA 2QCJA 2I42A 4QDIA 2PQ5A 1ECVA 3QKQA 2H02A 3AWFA 1SUGA 2GP0A 4GFUA 1A5YA 2VEUA 1KAVA 5KA1A 2PI7A 1BZCA 5KA7A 3EU0A 2FJNA 4WTYA 1FGSA 4HRFA 4QAHA 4CVMA 4KYQA 2I4EA 1Q6SA 3D9CA 5KABA 1RPMA 2GJTA 2QDCA 4AZ1A 2HY3A 1Q6PA 2HCMA 2XJAA 4IKCA 2BV5A 2WTZA 3NRSA 2VORA 4JMKA 1ZCKA 2VEWA 2NT7A 2R0BA 1GWZA 3V0FA 5KA2A 4QUNA 2WGPA 1XBOA 1OEMX 2CM7A 4Y14A 2F6VA 4DGXA 1XXPA 3BLTA 5MMZB 3ZMQA 4JNBA 4WOHA 2I3RA 2HC2A 5HDEA 3S3HA 1GQQA 4D3QA 2Y96A 3CWEA 1PA9A 2CNFA 3EZZA 1C85A 2VTDA 1XRIA 1OESA 3QCJA 3I80A 4RKKA 1YTNA 4H1OA 1YN9A 2NZ6A 2AM2A 3U96A 2F6ZA 4BUCA 4R0SA 1LYVA 5A5FA 1GQYA 4GS0A 1ONZA 1EEOA 3AWGA 1YPTA 2NTAA 4GRYA 4J51A 3QCHA 4S0GA 1Q6JA 1XXVA 2CMAA 3F9AA 5K24A 3V0GA 5A5EA 2A3KA 1G4WR 2JFFA 5K23A 2E0TA 2QDMA 3V0JA 2M3VA 4NWFA 2FH7A 3QCGA 2OZ5A 1PTUA 3QCKA 1NNYA 2H4VA 4QBWA 1EENA 1YGUA 1PYNA 3BLUA 5BZZA 2AZRA 4HJQA 1C84A 2J16B 1JLNA 2ZN7A 1MKPA 4D3PA 2CJZA 4QBEA 2QCTA 1BZHA 2F70A 3S3FA 2I6IA 2Q47A 2XPCA 3QCBA 3BRHA 2NT2A 5IBSA 2C46A 2RF6A 1YWFA 2HXPA 2H04A 2F6YA 4B04A 1V3AA 2JFGA 1P3DA 2I4HA 5BX1A 2J16A 1GG4A 2CNEA 4ZIYA 2OC3A 4HV4A 2BZLA 1Q1MA 2G59A 4RH5A 1E0DA 1C83A 4GFVA 2UUPA 2CM3A 1WAXA 2ZMMA 2BGDA 2HNQA 3CM3A 2I6OA 2YDUA 5KA3A 5EHRA 3D1OA 5K9WA 1I9TA 3HN7A 2P4DA 3H2XA 2I5XA 3ZM5A 2H03A 2X5OA 3OMHA 3B7OA 4OHEA 1W7KA 1YTWA 1YGRA 1T4JA 2C7SA 2J17A 2QBPA 4ZN5A 1PA1A 1FPRA 3ZM6A 2H4KA 5M43A 3RZ2A 5BZXA 1GFYA 1PTVA 2UAGA 3O3LA 1WRMA 1Q6NA 4KI9A 4GE5A 3MVNA 2PBNA 3D44A 4GWFA 2B4UA 2CFVA 1L8KA 4TVVA 5LXQB 3F81A 4YR8B 4OHHA 2VEVA 5KADA 1I9SA 4R30A 2OOQA 4ZI4A 2PSZA 2B4OA 2HC1A 1NWEA 3F99A 5J8RA 2OUDA 1OHDA 3S3KA 3QCFA 4BJOA 3QCNA 3SR9A 1NO6A 2GC5A 3LJ8A 1G4US 4RI4A 4H34A 3OLRA 2SHPA 2A8BA 5IBMA 3MOWA 3O4TA 1OETA 3PS5A 4GRZA 4CVLA 2B07A 1VHRA 2H4GA 3ZM0A 2QEPA 1PXHA 3V0HA 3ZM1A 3ZV2A 3D1HA 3SMEA 4QAPA 3N2AA
chains in the Genus database with same CATH topology
2P6XA 2I6JA 3RGOA 1KAKA 4HJPA 4RDDA 1RXDA 2BIJA 3QCDA 3V0IA 3MMJA 1T48A 2VEYA 4KYRA 2DXPA 3ZM2A 1XM2A 1ZC0A 2MBCA 1Q6TA 1QXKA 4OHDA 1NL9A 1J4XA 3ZMPA 1U26A 1G1HA 1R6HA 2F6FA 2CM2A 1LQFA 1U25A 2I3UA 1U24A 3S4OA 5K22A 2F6WA 1PTTA 1FPZA 3D1QA 3F9BA 3ZM3A 2B49A 3NMEA 3S3EA 4ZRTA 4BPCA 1OHCA 3BM8A 2B4PA 2VEXA 4WU3A 2HB1A 3QCMA 4JBCA 5EHPA 2CNGA 4Z6BA 4I8NA 4R0TA 1G1GA 4D3RA 5KA4A 1AAXA 5KACA 4NNDA 4WU2A 3GXGA 1PH0A 2CMCA 1OEUA 3M4UA 5AWXA 3EAXA 2I4GA 1G1FA 1BZJA 4JMJA 1YZ4A 1L8GA 2CNIA 2PA5A 1FQ1A 4MBBA 1ZZWA 4ERCA 2QBSA 1I57A 2F71A 3EMUA 4OHIA 3V0EA 2I75A 1X24A 2HNPA 5KAAA 2CMBA 3QCIA 1QZ0A 2G6ZA 1P15A 2NLKA 1T49A 1PTYA 1G7FA 2I6MA 1YFOA 3GXHA 2HVLA 1C88A 4GE2A 2CM8A 2FJMA 3I7ZA 5I6VA 3V0DA 1NWLA 4RHGA 3QKPA 5BUGA 4NX8A 3MOZA 2BGEA 3EB1A 2NV5A 1ONYA 2PT0A 3A5JA 3S4EA 1G7GA 4ICZA 2F46A 4Y2EA 2I1YA 3QCCA 5K9VA 2F6TA 2B3OA 2I6PA 2QBQA 1OEVA 3RGQA 2QDPA 4RI5A 2AHSA 5K25A 2IMGA 3QCEA 2JJDA 3F41A 3A5KA 5KA0A 2Y2FA 1OEOX 1LARA 4NWGA 3QCLA 1C87A 1C86A 3N0AA 3O4UA 3O4SA 4RH9A 2ESBA 4PYHA 1ZCLA 2Q05A 2CNHA 2QBRA 2B4SA 4NYHA 2GWOA 1NZ7A 4QUMA 5KA9A 3RO1A 4GE6A 1D5RA 1YTSA 4OHLA 1JF7A 1OHEA 3I36A 4YAAA 5GTJA 1M3GA 1WCHA 4DGPA 3AWEA 5KA8A 1Q6MA 3D42A 4PVGA 3O5XA 2QCJA 2I42A 2PQ5A 1ECVA 3QKQA 2H02A 3AWFA 1SUGA 2GP0A 4GFUA 1A5YA 2VEUA 1KAVA 5KA1A 2PI7A 1BZCA 5KA7A 3EU0A 2FJNA 4WTYA 4HRFA 4QAHA 4KYQA 2I4EA 1Q6SA 3D9CA 5KABA 1RPMA 2GJTA 2QDCA 4AZ1A 2HY3A 1Q6PA 2HCMA 4IKCA 2BV5A 4JMKA 1ZCKA 2VEWA 2NT7A 2R0BA 1GWZA 3V0FA 5KA2A 4QUNA 2WGPA 1XBOA 1OEMX 2CM7A 4Y14A 2F6VA 4DGXA 1XXPA 3BLTA 5MMZB 3ZMQA 4JNBA 4WOHA 2I3RA 2HC2A 5HDEA 3S3HA 4D3QA 2Y96A 3CWEA 1PA9A 2CNFA 3EZZA 1C85A 1XRIA 1OESA 3QCJA 3I80A 4RKKA 1YTNA 4H1OA 1YN9A 2NZ6A 3U96A 2F6ZA 4R0SA 1LYVA 4GS0A 1ONZA 1EEOA 3AWGA 1YPTA 2NTAA 4GRYA 4J51A 3QCHA 4S0GA 1Q6JA 1XXVA 2CMAA 3F9AA 5K24A 3V0GA 2A3KA 1G4WR 5K23A 2E0TA 2QDMA 3V0JA 2M3VA 4NWFA 2FH7A 3QCGA 2OZ5A 1PTUA 3QCKA 1NNYA 2H4VA 4QBWA 1EENA 1YGUA 1PYNA 3BLUA 5BZZA 2AZRA 4HJQA 1C84A 2J16B 1JLNA 2ZN7A 1MKPA 4D3PA 2CJZA 4QBEA 2QCTA 1BZHA 2F70A 3S3FA 2I6IA 2Q47A 3QCBA 3BRHA 2NT2A 5IBSA 2C46A 2RF6A 1YWFA 2HXPA 2H04A 2F6YA 4B04A 1V3AA 2I4HA 5BX1A 2J16A 2CNEA 2OC3A 2BZLA 1Q1MA 2G59A 4RH5A 1C83A 4GFVA 2CM3A 1WAXA 2ZMMA 2BGDA 2HNQA 3CM3A 2I6OA 2YDUA 5KA3A 5EHRA 3D1OA 5K9WA 1I9TA 2P4DA 3H2XA 2I5XA 2H03A 3OMHA 3B7OA 4OHEA 1YTWA 1YGRA 1T4JA 2C7SA 2J17A 2QBPA 4ZN5A 1PA1A 1FPRA 2H4KA 5M43A 3RZ2A 5BZXA 1GFYA 1PTVA 3O3LA 1WRMA 1Q6NA 4KI9A 4GE5A 2PBNA 3D44A 4GWFA 2B4UA 2CFVA 1L8KA 4TVVA 5LXQB 3F81A 4YR8B 4OHHA 2VEVA 5KADA 1I9SA 4R30A 2OOQA 4ZI4A 2PSZA 2B4OA 2HC1A 1NWEA 3F99A 5J8RA 2OUDA 1OHDA 3S3KA 3QCFA 4BJOA 3QCNA 3SR9A 1NO6A 3LJ8A 1G4US 4RI4A 4H34A 3OLRA 2SHPA 2A8BA 5IBMA 3MOWA 3O4TA 1OETA 3PS5A 4GRZA 2B07A 1VHRA 2H4GA 3ZM0A 2QEPA 1PXHA 3V0HA 3ZM1A 3ZV2A 3D1HA 3SMEA 4QAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P6X A;  2I6J A;  3RGO A;  1KAK A;  4HJP A;  4RDD A;  1RXD A;  2BIJ A;  3QCD A;  3V0I A;  3MMJ A;  1T48 A;  2VEY A;  4KYR A;  2DXP A;  3ZM2 A;  1XM2 A;  1ZC0 A;  2MBC A;  1Q6T A;  1QXK A;  4OHD A;  1NL9 A;  1J4X A;  3ZMP A;  1U26 A;  1G1H A;  1R6H A;  2F6F A;  2CM2 A;  1LQF A;  1U25 A;  2I3U A;  1U24 A;  3S4O A;  5K22 A;  2F6W A;  1PTT A;  1FPZ A;  3D1Q A;  3F9B A;  3ZM3 A;  2B49 A;  3NME A;  3S3E A;  4ZRT A;  4BPC A;  1OHC A;  3BM8 A;  2B4P A;  2VEX A;  4WU3 A;  2HB1 A;  3QCM A;  4JBC A;  5EHP A;  2CNG A;  4Z6B A;  4I8N A;  4R0T A;  1G1G A;  4D3R A;  5KA4 A;  1AAX A;  5KAC A;  4NND A;  4WU2 A;  3GXG A;  1PH0 A;  2CMC A;  1OEU A;  3M4U A;  5AWX A;  3EAX A;  2I4G A;  1G1F A;  1BZJ A;  4JMJ A;  1YZ4 A;  1L8G A;  2CNI A;  2PA5 A;  1FQ1 A;  4MBB A;  1ZZW A;  4ERC A;  2QBS A;  1I57 A;  2F71 A;  3EMU A;  4OHI A;  3V0E A;  2I75 A;  1X24 A;  2HNP A;  5KAA A;  2CMB A;  3QCI A;  1QZ0 A;  2G6Z A;  1P15 A;  2NLK A;  1T49 A;  1PTY A;  1G7F A;  2I6M A;  1YFO A;  3GXH A;  2HVL A;  1C88 A;  4GE2 A;  2CM8 A;  2FJM A;  3I7Z A;  5I6V A;  3V0D A;  1NWL A;  4RHG A;  3QKP A;  5BUG A;  4NX8 A;  3MOZ A;  2BGE A;  3EB1 A;  2NV5 A;  1ONY A;  2PT0 A;  3A5J A;  3S4E A;  1G7G A;  4ICZ A;  2F46 A;  4Y2E A;  2I1Y A;  3QCC A;  5K9V A;  2F6T A;  2B3O A;  2I6P A;  2QBQ A;  1OEV A;  3RGQ A;  2QDP A;  4RI5 A;  2AHS A;  5K25 A;  2IMG A;  3QCE A;  2JJD A;  3F41 A;  3A5K A;  5KA0 A;  2Y2F A;  1OEO X;  1LAR A;  4NWG A;  3QCL A;  1C87 A;  1C86 A;  3N0A A;  3O4U A;  3O4S A;  4RH9 A;  2ESB A;  4PYH A;  1ZCL A;  2Q05 A;  2CNH A;  2QBR A;  2B4S A;  4NYH A;  2GWO A;  1NZ7 A;  4QUM A;  5KA9 A;  3RO1 A;  4GE6 A;  1D5R A;  1YTS A;  4OHL A;  1JF7 A;  1OHE A;  3I36 A;  4YAA A;  5GTJ A;  1M3G A;  1WCH A;  4DGP A;  3AWE A;  5KA8 A;  1Q6M A;  3D42 A;  4PVG A;  3O5X A;  2QCJ A;  2I42 A;  2PQ5 A;  1ECV A;  3QKQ A;  2H02 A;  3AWF A;  1SUG A;  2GP0 A;  4GFU A;  1A5Y A;  2VEU A;  1KAV A;  5KA1 A;  2PI7 A;  1BZC A;  5KA7 A;  3EU0 A;  2FJN A;  4WTY A;  4HRF A;  4QAH A;  4KYQ A;  2I4E A;  1Q6S A;  3D9C A;  5KAB A;  1RPM A;  2GJT A;  2QDC A;  4AZ1 A;  2HY3 A;  1Q6P A;  2HCM A;  4IKC A;  2BV5 A;  4JMK A;  1ZCK A;  2VEW A;  2NT7 A;  2R0B A;  1GWZ A;  3V0F A;  5KA2 A;  4QUN A;  2WGP A;  1XBO A;  1OEM X;  2CM7 A;  4Y14 A;  2F6V A;  4DGX A;  1XXP A;  3BLT A;  5MMZ B;  3ZMQ A;  4JNB A;  4WOH A;  2I3R A;  2HC2 A;  5HDE A;  3S3H A;  4D3Q A;  2Y96 A;  3CWE A;  1PA9 A;  2CNF A;  3EZZ A;  1C85 A;  1XRI A;  1OES A;  3QCJ A;  3I80 A;  4RKK A;  1YTN A;  4H1O A;  1YN9 A;  2NZ6 A;  3U96 A;  2F6Z A;  4R0S A;  1LYV A;  4GS0 A;  1ONZ A;  1EEO A;  3AWG A;  1YPT A;  2NTA A;  4GRY A;  4J51 A;  3QCH A;  4S0G A;  1Q6J A;  1XXV A;  2CMA A;  3F9A A;  5K24 A;  3V0G A;  2A3K A;  1G4W R;  5K23 A;  2E0T A;  2QDM A;  3V0J A;  2M3V A;  4NWF A;  2FH7 A;  3QCG A;  2OZ5 A;  1PTU A;  3QCK A;  1NNY A;  2H4V A;  4QBW A;  1EEN A;  1YGU A;  1PYN A;  3BLU A;  5BZZ A;  2AZR A;  4HJQ A;  1C84 A;  2J16 B;  1JLN A;  2ZN7 A;  1MKP A;  4D3P A;  2CJZ A;  4QBE A;  2QCT A;  1BZH A;  2F70 A;  3S3F A;  2I6I A;  2Q47 A;  3QCB A;  3BRH A;  2NT2 A;  5IBS A;  2C46 A;  2RF6 A;  1YWF A;  2HXP A;  2H04 A;  2F6Y A;  4B04 A;  1V3A A;  2I4H A;  5BX1 A;  2J16 A;  2CNE A;  2OC3 A;  2BZL A;  1Q1M A;  2G59 A;  4RH5 A;  1C83 A;  4GFV A;  2CM3 A;  1WAX A;  2ZMM A;  2BGD A;  2HNQ A;  3CM3 A;  2I6O A;  2YDU A;  5KA3 A;  5EHR A;  3D1O A;  5K9W A;  1I9T A;  2P4D A;  3H2X A;  2I5X A;  2H03 A;  3OMH A;  3B7O A;  4OHE A;  1YTW A;  1YGR A;  1T4J A;  2C7S A;  2J17 A;  2QBP A;  4ZN5 A;  1PA1 A;  1FPR A;  2H4K A;  5M43 A;  3RZ2 A;  5BZX A;  1GFY A;  1PTV A;  3O3L A;  1WRM A;  1Q6N A;  4KI9 A;  4GE5 A;  2PBN A;  3D44 A;  4GWF A;  2B4U A;  2CFV A;  1L8K A;  4TVV A;  5LXQ B;  3F81 A;  4YR8 B;  4OHH A;  2VEV A;  5KAD A;  1I9S A;  4R30 A;  2OOQ A;  4ZI4 A;  2PSZ A;  2B4O A;  2HC1 A;  1NWE A;  3F99 A;  5J8R A;  2OUD A;  1OHD A;  3S3K A;  3QCF A;  4BJO A;  3QCN A;  3SR9 A;  1NO6 A;  3LJ8 A;  1G4U S;  4RI4 A;  4H34 A;  3OLR A;  2SHP A;  2A8B A;  5IBM A;  3MOW A;  3O4T A;  1OET A;  3PS5 A;  4GRZ A;  2B07 A;  1VHR A;  2H4G A;  3ZM0 A;  2QEP A;  1PXH A;  3V0H A;  3ZM1 A;  3ZV2 A;  3D1H A;  3SME A;  4QAP A; 
#chains in the Genus database with same CATH topology
 2P6X A;  1W78 A;  2I6J A;  3RGO A;  1KAK A;  1JBW A;  4UAG A;  4HJP A;  4RDD A;  1RXD A;  2BIJ A;  3QCD A;  3V0I A;  3MMJ A;  1T48 A;  2VEY A;  4KYR A;  4CVK A;  2DXP A;  3ZM2 A;  1XM2 A;  1ZC0 A;  2MBC A;  1Q6T A;  1QXK A;  4OHD A;  2Y66 A;  1NL9 A;  1J4X A;  3ZMP A;  2GCB A;  1U26 A;  2VOS A;  1G1H A;  1R6H A;  3ZL8 A;  2F6F A;  2CM2 A;  1LQF A;  1U25 A;  2I3U A;  3PYZ A;  1U24 A;  3S4O A;  2GCA A;  5K22 A;  2F6W A;  1PTT A;  1FPZ A;  3D1Q A;  3F9B A;  3ZM3 A;  2B49 A;  3NME A;  3S3E A;  4ZRT A;  4BPC A;  1OHC A;  3BM8 A;  2B4P A;  2VEX A;  4WU3 A;  2HB1 A;  2AM1 A;  3QCM A;  4JBC A;  5EHP A;  2CNG A;  4Z6B A;  4I8N A;  4R0T A;  1G1G A;  4D3R A;  5KA4 A;  1AAX A;  5KAC A;  4NND A;  4WU2 A;  3GXG A;  1PH0 A;  2CMC A;  1OEU A;  3M4U A;  5AWX A;  3EAX A;  2I4G A;  1G1F A;  4QF5 A;  1BZJ A;  4JMJ A;  1YZ4 A;  1L8G A;  2CNI A;  2PA5 A;  2WJP A;  1FQ1 A;  3LK7 A;  4MBB A;  1ZZW A;  4ERC A;  2QBS A;  1I57 A;  2F71 A;  3EMU A;  4OHI A;  3V0E A;  2I75 A;  1X24 A;  2HNP A;  5KAA A;  2CMB A;  3QCI A;  1QZ0 A;  2G6Z A;  2JFH A;  1P15 A;  2NLK A;  1T49 A;  1PTY A;  1EEH A;  1G7F A;  2I6M A;  1YFO A;  3GXH A;  2HVL A;  1C88 A;  4GE2 A;  2CM8 A;  1UAG A;  2FJM A;  3I7Z A;  5I6V A;  3V0D A;  1NWL A;  4RHG A;  3QKP A;  5BUG A;  4NX8 A;  2GC6 A;  3MOZ A;  2BGE A;  3EB1 A;  4C12 A;  2NV5 A;  1ONY A;  1E8C A;  4BUB A;  2PT0 A;  3A5J A;  3S4E A;  1G7G A;  4ICZ A;  2F46 A;  4Y2E A;  2Y67 A;  2I1Y A;  3QCC A;  5K9V A;  2F6T A;  2B3O A;  2I6P A;  1O5Z A;  2QBQ A;  1OEV A;  3RGQ A;  2QDP A;  4RI5 A;  2AHS A;  5K25 A;  2UUO A;  1JBV A;  2IMG A;  3QCE A;  2JJD A;  3F41 A;  3UAG A;  2Y68 A;  3A5K A;  5KA0 A;  2Y2F A;  3QCZ A;  1P31 A;  2F00 A;  1OEO X;  1LAR A;  2VTE A;  4NWG A;  1C87 A;  3QCL A;  1C86 A;  3N0A A;  1J6U A;  3O4U A;  3O4S A;  4RH9 A;  2ESB A;  4PYH A;  4C13 A;  1ZCL A;  2Q05 A;  2CNH A;  2QBR A;  2B4S A;  4NYH A;  2GWO A;  1NZ7 A;  4QUM A;  5KA9 A;  3RO1 A;  4GE6 A;  1D5R A;  1YTS A;  4OHL A;  1JF7 A;  1OHE A;  3I36 A;  4YAA A;  5GTJ A;  1M3G A;  2Y1O A;  1WCH A;  4DGP A;  3AWE A;  5KA8 A;  1Q6M A;  3D42 A;  4PVG A;  3O5X A;  2QCJ A;  2I42 A;  4QDI A;  2PQ5 A;  1ECV A;  3QKQ A;  2H02 A;  3AWF A;  1SUG A;  2GP0 A;  4GFU A;  1A5Y A;  2VEU A;  1KAV A;  5KA1 A;  2PI7 A;  1BZC A;  5KA7 A;  3EU0 A;  2FJN A;  4WTY A;  1FGS A;  4HRF A;  4QAH A;  4CVM A;  4KYQ A;  2I4E A;  1Q6S A;  3D9C A;  5KAB A;  1RPM A;  2GJT A;  2QDC A;  4AZ1 A;  2HY3 A;  1Q6P A;  2HCM A;  2XJA A;  4IKC A;  2BV5 A;  2WTZ A;  3NRS A;  2VOR A;  4JMK A;  1ZCK A;  2VEW A;  2NT7 A;  2R0B A;  1GWZ A;  3V0F A;  5KA2 A;  4QUN A;  2WGP A;  1XBO A;  1OEM X;  2CM7 A;  4Y14 A;  2F6V A;  4DGX A;  1XXP A;  3BLT A;  5MMZ B;  3ZMQ A;  4JNB A;  4WOH A;  2I3R A;  2HC2 A;  5HDE A;  3S3H A;  1GQQ A;  4D3Q A;  2Y96 A;  3CWE A;  1PA9 A;  2CNF A;  3EZZ A;  1C85 A;  2VTD A;  1XRI A;  1OES A;  3QCJ A;  3I80 A;  4RKK A;  1YTN A;  4H1O A;  1YN9 A;  2NZ6 A;  2AM2 A;  3U96 A;  2F6Z A;  4BUC A;  4R0S A;  1LYV A;  5A5F A;  1GQY A;  4GS0 A;  1ONZ A;  1EEO A;  3AWG A;  1YPT A;  2NTA A;  4GRY A;  4J51 A;  3QCH A;  4S0G A;  1Q6J A;  1XXV A;  2CMA A;  3F9A A;  5K24 A;  3V0G A;  5A5E A;  2A3K A;  1G4W R;  2JFF A;  5K23 A;  2E0T A;  2QDM A;  3V0J A;  2M3V A;  4NWF A;  2FH7 A;  3QCG A;  2OZ5 A;  1PTU A;  3QCK A;  1NNY A;  2H4V A;  4QBW A;  1EEN A;  1YGU A;  1PYN A;  3BLU A;  5BZZ A;  2AZR A;  4HJQ A;  1C84 A;  2J16 B;  1JLN A;  2ZN7 A;  1MKP A;  4D3P A;  2CJZ A;  4QBE A;  2QCT A;  1BZH A;  2F70 A;  3S3F A;  2I6I A;  2Q47 A;  2XPC A;  3QCB A;  3BRH A;  2NT2 A;  5IBS A;  2C46 A;  2RF6 A;  1YWF A;  2HXP A;  2H04 A;  2F6Y A;  4B04 A;  1V3A A;  2JFG A;  1P3D A;  2I4H A;  5BX1 A;  2J16 A;  1GG4 A;  2CNE A;  4ZIY A;  2OC3 A;  4HV4 A;  2BZL A;  1Q1M A;  2G59 A;  4RH5 A;  1E0D A;  1C83 A;  4GFV A;  2UUP A;  2CM3 A;  1WAX A;  2ZMM A;  2BGD A;  2HNQ A;  3CM3 A;  2I6O A;  2YDU A;  5KA3 A;  5EHR A;  3D1O A;  5K9W A;  1I9T A;  3HN7 A;  2P4D A;  3H2X A;  2I5X A;  3ZM5 A;  2H03 A;  2X5O A;  3OMH A;  3B7O A;  4OHE A;  1W7K A;  1YTW A;  1YGR A;  1T4J A;  2C7S A;  2J17 A;  2QBP A;  4ZN5 A;  1PA1 A;  1FPR A;  3ZM6 A;  2H4K A;  5M43 A;  3RZ2 A;  5BZX A;  1GFY A;  1PTV A;  2UAG A;  3O3L A;  1WRM A;  1Q6N A;  4KI9 A;  4GE5 A;  3MVN A;  2PBN A;  3D44 A;  4GWF A;  2B4U A;  2CFV A;  1L8K A;  4TVV A;  5LXQ B;  3F81 A;  4YR8 B;  4OHH A;  2VEV A;  5KAD A;  1I9S A;  4R30 A;  2OOQ A;  4ZI4 A;  2PSZ A;  2B4O A;  2HC1 A;  1NWE A;  3F99 A;  5J8R A;  2OUD A;  1OHD A;  3S3K A;  3QCF A;  4BJO A;  3QCN A;  3SR9 A;  1NO6 A;  2GC5 A;  3LJ8 A;  1G4U S;  4RI4 A;  4H34 A;  3OLR A;  2SHP A;  2A8B A;  5IBM A;  3MOW A;  3O4T A;  1OET A;  3PS5 A;  4GRZ A;  4CVL A;  2B07 A;  1VHR A;  2H4G A;  3ZM0 A;  2QEP A;  1PXH A;  3V0H A;  3ZM1 A;  3ZV2 A;  3D1H A;  3SME A;  4QAP A;  3N2A A; 
#chains in the Genus database with same CATH homology
 2P6X A;  2I6J A;  3RGO A;  1KAK A;  4HJP A;  4RDD A;  1RXD A;  2BIJ A;  3QCD A;  3V0I A;  3MMJ A;  1T48 A;  2VEY A;  4KYR A;  2DXP A;  3ZM2 A;  1XM2 A;  1ZC0 A;  2MBC A;  1Q6T A;  1QXK A;  4OHD A;  1NL9 A;  1J4X A;  3ZMP A;  1U26 A;  1G1H A;  1R6H A;  2F6F A;  2CM2 A;  1LQF A;  1U25 A;  2I3U A;  1U24 A;  3S4O A;  5K22 A;  2F6W A;  1PTT A;  1FPZ A;  3D1Q A;  3F9B A;  3ZM3 A;  2B49 A;  3NME A;  3S3E A;  4ZRT A;  4BPC A;  1OHC A;  3BM8 A;  2B4P A;  2VEX A;  4WU3 A;  2HB1 A;  3QCM A;  4JBC A;  5EHP A;  2CNG A;  4Z6B A;  4I8N A;  4R0T A;  1G1G A;  4D3R A;  5KA4 A;  1AAX A;  5KAC A;  4NND A;  4WU2 A;  3GXG A;  1PH0 A;  2CMC A;  1OEU A;  3M4U A;  5AWX A;  3EAX A;  2I4G A;  1G1F A;  1BZJ A;  4JMJ A;  1YZ4 A;  1L8G A;  2CNI A;  2PA5 A;  1FQ1 A;  4MBB A;  1ZZW A;  4ERC A;  2QBS A;  1I57 A;  2F71 A;  3EMU A;  4OHI A;  3V0E A;  2I75 A;  1X24 A;  2HNP A;  5KAA A;  2CMB A;  3QCI A;  1QZ0 A;  2G6Z A;  1P15 A;  2NLK A;  1T49 A;  1PTY A;  1G7F A;  2I6M A;  1YFO A;  3GXH A;  2HVL A;  1C88 A;  4GE2 A;  2CM8 A;  2FJM A;  3I7Z A;  5I6V A;  3V0D A;  1NWL A;  4RHG A;  3QKP A;  5BUG A;  4NX8 A;  3MOZ A;  2BGE A;  3EB1 A;  2NV5 A;  1ONY A;  2PT0 A;  3A5J A;  3S4E A;  1G7G A;  4ICZ A;  2F46 A;  4Y2E A;  2I1Y A;  3QCC A;  5K9V A;  2F6T A;  2B3O A;  2I6P A;  2QBQ A;  1OEV A;  3RGQ A;  2QDP A;  4RI5 A;  2AHS A;  5K25 A;  2IMG A;  3QCE A;  2JJD A;  3F41 A;  3A5K A;  5KA0 A;  2Y2F A;  1OEO X;  1LAR A;  4NWG A;  3QCL A;  1C87 A;  1C86 A;  3N0A A;  3O4U A;  3O4S A;  4RH9 A;  2ESB A;  4PYH A;  1ZCL A;  2Q05 A;  2CNH A;  2QBR A;  2B4S A;  4NYH A;  2GWO A;  1NZ7 A;  4QUM A;  5KA9 A;  3RO1 A;  4GE6 A;  1D5R A;  1YTS A;  4OHL A;  1JF7 A;  1OHE A;  3I36 A;  4YAA A;  5GTJ A;  1M3G A;  1WCH A;  4DGP A;  3AWE A;  5KA8 A;  1Q6M A;  3D42 A;  4PVG A;  3O5X A;  2QCJ A;  2I42 A;  2PQ5 A;  1ECV A;  3QKQ A;  2H02 A;  3AWF A;  1SUG A;  2GP0 A;  4GFU A;  1A5Y A;  2VEU A;  1KAV A;  5KA1 A;  2PI7 A;  1BZC A;  5KA7 A;  3EU0 A;  2FJN A;  4WTY A;  4HRF A;  4QAH A;  4KYQ A;  2I4E A;  1Q6S A;  3D9C A;  5KAB A;  1RPM A;  2GJT A;  2QDC A;  4AZ1 A;  2HY3 A;  1Q6P A;  2HCM A;  4IKC A;  2BV5 A;  4JMK A;  1ZCK A;  2VEW A;  2NT7 A;  2R0B A;  1GWZ A;  3V0F A;  5KA2 A;  4QUN A;  2WGP A;  1XBO A;  1OEM X;  2CM7 A;  4Y14 A;  2F6V A;  4DGX A;  1XXP A;  3BLT A;  5MMZ B;  3ZMQ A;  4JNB A;  4WOH A;  2I3R A;  2HC2 A;  5HDE A;  3S3H A;  4D3Q A;  2Y96 A;  3CWE A;  1PA9 A;  2CNF A;  3EZZ A;  1C85 A;  1XRI A;  1OES A;  3QCJ A;  3I80 A;  4RKK A;  1YTN A;  4H1O A;  1YN9 A;  2NZ6 A;  3U96 A;  2F6Z A;  4R0S A;  1LYV A;  4GS0 A;  1ONZ A;  1EEO A;  3AWG A;  1YPT A;  2NTA A;  4GRY A;  4J51 A;  3QCH A;  4S0G A;  1Q6J A;  1XXV A;  2CMA A;  3F9A A;  5K24 A;  3V0G A;  2A3K A;  1G4W R;  5K23 A;  2E0T A;  2QDM A;  3V0J A;  2M3V A;  4NWF A;  2FH7 A;  3QCG A;  2OZ5 A;  1PTU A;  3QCK A;  1NNY A;  2H4V A;  4QBW A;  1EEN A;  1YGU A;  1PYN A;  3BLU A;  5BZZ A;  2AZR A;  4HJQ A;  1C84 A;  2J16 B;  1JLN A;  2ZN7 A;  1MKP A;  4D3P A;  2CJZ A;  4QBE A;  2QCT A;  1BZH A;  2F70 A;  3S3F A;  2I6I A;  2Q47 A;  3QCB A;  3BRH A;  2NT2 A;  5IBS A;  2C46 A;  2RF6 A;  1YWF A;  2HXP A;  2H04 A;  2F6Y A;  4B04 A;  1V3A A;  2I4H A;  5BX1 A;  2J16 A;  2CNE A;  2OC3 A;  2BZL A;  1Q1M A;  2G59 A;  4RH5 A;  1C83 A;  4GFV A;  2CM3 A;  1WAX A;  2ZMM A;  2BGD A;  2HNQ A;  3CM3 A;  2I6O A;  2YDU A;  5KA3 A;  5EHR A;  3D1O A;  5K9W A;  1I9T A;  2P4D A;  3H2X A;  2I5X A;  2H03 A;  3OMH A;  3B7O A;  4OHE A;  1YTW A;  1YGR A;  1T4J A;  2C7S A;  2J17 A;  2QBP A;  4ZN5 A;  1PA1 A;  1FPR A;  2H4K A;  5M43 A;  3RZ2 A;  5BZX A;  1GFY A;  1PTV A;  3O3L A;  1WRM A;  1Q6N A;  4KI9 A;  4GE5 A;  2PBN A;  3D44 A;  4GWF A;  2B4U A;  2CFV A;  1L8K A;  4TVV A;  5LXQ B;  3F81 A;  4YR8 B;  4OHH A;  2VEV A;  5KAD A;  1I9S A;  4R30 A;  2OOQ A;  4ZI4 A;  2PSZ A;  2B4O A;  2HC1 A;  1NWE A;  3F99 A;  5J8R A;  2OUD A;  1OHD A;  3S3K A;  3QCF A;  4BJO A;  3QCN A;  3SR9 A;  1NO6 A;  3LJ8 A;  1G4U S;  4RI4 A;  4H34 A;  3OLR A;  2SHP A;  2A8B A;  5IBM A;  3MOW A;  3O4T A;  1OET A;  3PS5 A;  4GRZ A;  2B07 A;  1VHR A;  2H4G A;  3ZM0 A;  2QEP A;  1PXH A;  3V0H A;  3ZM1 A;  3ZV2 A;  3D1H A;  3SME A;  4QAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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