2ZMMA

Crystal structure of ptp1b-inhibitor complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 108
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2008-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2zmmA00
4ZI4A 1YN9A 3S4OA 1J4XA 4DGPA 1ONZA 4QBEA 3GXHA 4RDDA 1NWEA 1P15A 3AWGA 4ICZA 3QCGA 2I6OA 3CWEA 1C87A 2PSZA 3MOZA 1U25A 1I57A 1XXVA 4JNBA 2PT0A 4OHHA 1G1GA 1X24A 5EHPA 2P4DA 2CMBA 1Q6SA 4OHLA 3S3HA 2I1YA 3U96A 4GFUA 2BV5A 2HC2A 2PBNA 4ZN5A 2Y96A 3D1OA 1PTUA 5HDEA 2CNFA 4KI9A 2CFVA 4DGXA 2HB1A 4QAPA 2QEPA 3RZ2A 3OMHA 2P6XA 1YGRA 4R0SA 2PI7A 5KA9A 1C83A 1PA1A 3V0HA 3B7OA 1C85A 2NLKA 2BGDA 2VEXA 1OEUA 4QBWA 4D3PA 4D3RA 3LJ8A 2CNHA 3EB1A 1R6HA 5KA3A 2F6WA 5KA4A 1NL9A 1OETA 4S0GA 4NYHA 4KYQA 3QCNA 1RPMA 1Q1MA 1WCHA 2I75A 2NZ6A 2R0BA 1OEMX 5KABA 1OEOX 2AZRA 1VHRA 2CM7A 4JMKA 3QCKA 4GRZA 2F6YA 2MBCA 4NX8A 2NTAA 5AWXA 2B07A 1OESA 3QCCA 1SUGA 3AWFA 4RI5A 3D42A 2I6JA 4BPCA 2QBQA 3D1QA 2B4SA 1YTNA 2FH7A 2QCTA 2HY3A 1XRIA 3EZZA 4RH5A 1T48A 1ZC0A 1ECVA 1YTSA 3I80A 3V0IA 2B3OA 1PTVA 4TVVA 5KACA 2CJZA 4R0TA 2CNEA 2HVLA 4GE2A 3F9AA 3I36A 4QUMA 2B4UA 1G1HA 2VEWA 2GWOA 3MOWA 1U26A 4IKCA 5K9VA 4HJPA 3QCFA 3F81A 4ERCA 1YWFA 2QDMA 5K22A 1NNYA 5M43A 3QKQA 3RGOA 2HNQA 4B04A 1G4WR 5KA8A 3O5XA 3QCJA 2F70A 3QCDA 1BZCA 4WTYA 4BJOA 2OOQA 2I4GA 2H4KA 4GRYA 2Q47A 3V0JA 1L8GA 1XM2A 5KA7A 2NV5A 3BM8A 3RGQA 4Y2EA 4OHEA 3ZM0A 1YFOA 1G7FA 4HJQA 4OHDA 2I6MA 1PXHA 2H4VA 3QCLA 1RXDA 3S3FA 4QAHA 2H03A 1ONYA 5LXQB 2G59A 5BZZA 4HRFA 5K9WA 2B4PA 1LARA 4J51A 2GP0A 1I9SA 3F99A 5K23A 1JLNA 2BGEA 2HC1A 3GXGA 2C46A 5MMZB 3QCMA 3H2XA 4R30A 4H1OA 4PYHA 3ZV2A 2AHSA 1D5RA 5KADA 2A3KA 4D3QA 4KYRA 1NWLA 2FJMA 2VEVA 2I3UA 3QCBA 2I4EA 3MMJA 2NT7A 1NO6A 3ZMPA 2ESBA 1WRMA 2FJNA 2B49A 3QCIA 1PH0A 3QCHA 2Q05A 1L8KA 5KA0A 5I6VA 2I3RA 4NWFA 2CNIA 3M4UA 2QBRA 4RHGA 2VEUA 2QCJA 3EU0A 1Q6PA 5J8RA 3CM3A 4H34A 2F71A 4GE6A 5KAAA 5GTJA 2ZMMA 2F46A 1C86A 1OHCA 2F6VA 2C7SA 5IBSA 1U24A 2VEYA 4MBBA 4WU2A 3V0EA 5BUGA 2RF6A 4NWGA 1C84A 2OZ5A 1BZHA 4JBCA 5EHRA 3D9CA 1Q6JA 2B4OA 5K25A 2HXPA 4RKKA 3ZMQA 3RO1A 1OHEA 3QCEA 2F6ZA 3F41A 1G4US 4Y14A 5IBMA 3ZM3A 3V0FA 2I42A 4GE5A 1JF7A 1PTYA 2J17A 1V3AA 3ZM2A 2IMGA 4YAAA 2F6FA 2I6PA 1FPZA 2Y2FA 1M3GA 2QDCA 3BLTA 3F9BA 3EAXA 3O4TA 3I7ZA 3O4UA 1LYVA 4WOHA 3O3LA 1GFYA 2WGPA 3ZM1A 2J16B 2JJDA 4GS0A 3NMEA 3SMEA 2QDPA 2CNGA 1ZCKA 2OUDA 3V0GA 1YTWA 1Q6MA 1FQ1A 4PVGA 5KA2A 3O4SA 1I9TA 1T49A 2YDUA 4AZ1A 3AWEA 1BZJA 1G7GA 2F6TA 2H02A 1PYNA 2CMCA 2CM8A 2J16A 1G1FA 3EMUA 5KA1A 3S3KA 1KAKA 3V0DA 3D1HA 1EEOA 2GJTA 1LQFA 4OHIA 2G6ZA 1ZCLA 3QKPA 2I4HA 1QZ0A 2DXPA 1PTTA 2HCMA 2OC3A 1YPTA 3BRHA 1T4JA 1PA9A 2HNPA 3S3EA 3SR9A 4RI4A 2BZLA 4GWFA 4ZRTA 1Q6TA 2QBSA 2NT2A 1MKPA 1YGUA 1WAXA 1YZ4A 3A5KA 3PS5A 1A5YA 4WU3A 4RH9A 1ZZWA 3S4EA 1NZ7A 3A5JA 1Q6NA 1QXKA 1GWZA 5K24A 5BZXA 4QUNA 4NNDA 1EENA 5BX1A 1FPRA 1OEVA 2E0TA 3BLUA 2I5XA 3OLRA 2CMAA 2PQ5A 3D44A 4JMJA 2BIJA 1C88A 2CM3A 2SHPA 1KAVA 2QBPA 1XXPA 4GFVA 2PA5A 3N0AA 4I8NA 2CM2A 2ZN7A 4Z6BA 2I6IA 1XBOA 4YR8B 1AAXA 1OHDA 2H04A 2M3VA 2H4GA 2A8BA
chains in the Genus database with same CATH superfamily
5A5EA 4ZI4A 1YN9A 3S4OA 1J4XA 4DGPA 1ONZA 4QBEA 3GXHA 4RDDA 1NWEA 1P15A 3N2AA 3AWGA 4ICZA 1J6UA 3QCGA 2I6OA 3CWEA 1C87A 2PSZA 3MOZA 1U25A 1I57A 1XXVA 4JNBA 2PT0A 4OHHA 1G1GA 2Y1OA 1X24A 5EHPA 2P4DA 2CMBA 1Q6SA 4OHLA 1E0DA 3S3HA 2I1YA 3U96A 4GFUA 2BV5A 2HC2A 2PBNA 4ZN5A 2Y96A 3D1OA 1PTUA 5HDEA 2XJAA 2CNFA 4KI9A 2CFVA 4DGXA 2X5OA 2AM1A 2HB1A 4QAPA 2QEPA 3RZ2A 3OMHA 2P6XA 1YGRA 4R0SA 1GQYA 2PI7A 5KA9A 1C83A 1PA1A 3V0HA 3B7OA 1C85A 2NLKA 2BGDA 2XPCA 2VEXA 3ZL8A 1OEUA 4QBWA 4D3PA 4D3RA 3LJ8A 2CNHA 3EB1A 1R6HA 5KA3A 2F6WA 5KA4A 2JFGA 1NL9A 1OETA 4S0GA 4CVKA 2AM2A 4NYHA 4KYQA 3QCNA 1RPMA 1Q1MA 1WCHA 2I75A 2NZ6A 2R0BA 1OEMX 5KABA 1OEOX 2AZRA 1VHRA 2CM7A 4JMKA 3QCKA 4GRZA 2F6YA 2MBCA 4NX8A 2NTAA 5AWXA 2B07A 1OESA 3QCCA 1SUGA 3AWFA 4RI5A 2VORA 3D42A 2I6JA 2UUPA 4BPCA 2QBQA 3D1QA 1O5ZA 2B4SA 1YTNA 2FH7A 2QCTA 2HY3A 1XRIA 3EZZA 4RH5A 1T48A 1ZC0A 1ECVA 1YTSA 3I80A 3V0IA 4QF5A 2B3OA 1PTVA 4TVVA 5KACA 2CJZA 4R0TA 2CNEA 2HVLA 4GE2A 3F9AA 3I36A 2VOSA 4QUMA 2GCBA 2B4UA 1G1HA 2VEWA 2GWOA 3MOWA 1U26A 4IKCA 5K9VA 4HJPA 3QCFA 3F81A 2Y68A 4ERCA 1YWFA 2QDMA 5K22A 3PYZA 1NNYA 3HN7A 5M43A 3QKQA 3RGOA 2HNQA 4B04A 1G4WR 5KA8A 3O5XA 3QCJA 2F70A 3QCDA 1BZCA 4WTYA 4BJOA 2OOQA 2I4GA 2H4KA 4GRYA 2Q47A 3V0JA 1L8GA 1XM2A 4C13A 5KA7A 2NV5A 3BM8A 3RGQA 4Y2EA 4OHEA 3ZM0A 1YFOA 1G7FA 4HJQA 2WJPA 4BUBA 4OHDA 2I6MA 1PXHA 2H4VA 3QCLA 1RXDA 3S3FA 4QAHA 2H03A 1ONYA 5LXQB 2G59A 2GCAA 5BZZA 4HRFA 5K9WA 2B4PA 1LARA 4J51A 2GP0A 1I9SA 3F99A 1FGSA 5K23A 1JLNA 2BGEA 2HC1A 4UAGA 3GXGA 2C46A 5MMZB 3QCMA 3H2XA 4R30A 4H1OA 4PYHA 3ZV2A 2AHSA 1D5RA 5KADA 1GG4A 3ZM5A 2A3KA 4D3QA 4KYRA 1NWLA 4ZIYA 2FJMA 2VEVA 2I3UA 3QCBA 2I4EA 3MMJA 2NT7A 1NO6A 3ZMPA 2ESBA 1WRMA 2FJNA 2B49A 3QCIA 3UAGA 1PH0A 3QCHA 2Q05A 1L8KA 5KA0A 5I6VA 2I3RA 4NWFA 2CNIA 3M4UA 2QBRA 4RHGA 2VEUA 2QCJA 3EU0A 1Q6PA 5J8RA 1JBVA 3CM3A 4H34A 2F71A 4GE6A 4QDIA 5GTJA 5KAAA 2ZMMA 2F46A 1C86A 1OHCA 2F6VA 2C7SA 5IBSA 1U24A 2VEYA 1JBWA 4MBBA 4WU2A 3V0EA 5BUGA 3NRSA 2RF6A 4NWGA 1C84A 2OZ5A 1BZHA 4JBCA 5EHRA 3D9CA 1Q6JA 2B4OA 5K25A 2HXPA 4RKKA 3ZMQA 3RO1A 1OHEA 3QCEA 2F6ZA 3F41A 1EEHA 1G4US 2VTEA 4Y14A 5IBMA 1P3DA 3ZM3A 3V0FA 2I42A 4GE5A 1JF7A 1PTYA 2J17A 1V3AA 3ZM2A 2IMGA 5A5FA 4YAAA 4CVLA 2F6FA 2I6PA 1FPZA 2Y2FA 1M3GA 2QDCA 3BLTA 1E8CA 1W78A 3F9BA 3EAXA 3O4TA 3I7ZA 3O4UA 1LYVA 4WOHA 3O3LA 1GFYA 2WGPA 3ZM1A 2J16B 2JJDA 4GS0A 4BUCA 3NMEA 2UAGA 3SMEA 2JFFA 1W7KA 2QDPA 2CNGA 1ZCKA 2OUDA 3V0GA 1YTWA 1Q6MA 3LK7A 1FQ1A 3ZM6A 4PVGA 3QCZA 5KA2A 3O4SA 1I9TA 1T49A 2YDUA 4AZ1A 3AWEA 1BZJA 1UAGA 1G7GA 2F6TA 2H02A 1PYNA 2CMCA 2CM8A 2JFHA 2J16A 1G1FA 3EMUA 5KA1A 3S3KA 1KAKA 3V0DA 3D1HA 1EEOA 2GJTA 1LQFA 4OHIA 1GQQA 1ZCLA 2G6ZA 3QKPA 2I4HA 1QZ0A 2DXPA 1PTTA 2HCMA 2OC3A 1YPTA 3BRHA 1T4JA 1PA9A 1P31A 2HNPA 4CVMA 3S3EA 3SR9A 4RI4A 2BZLA 4GWFA 4ZRTA 1Q6TA 2QBSA 2NT2A 1MKPA 1YGUA 1WAXA 1YZ4A 3A5KA 2UUOA 3PS5A 2F00A 3MVNA 1A5YA 4WU3A 4RH9A 1ZZWA 3S4EA 2GC6A 2GC5A 1NZ7A 3A5JA 1Q6NA 1QXKA 1GWZA 5K24A 5BZXA 4HV4A 4QUNA 4NNDA 1EENA 5BX1A 1FPRA 1OEVA 2E0TA 2WTZA 3BLUA 2I5XA 3OLRA 2CMAA 2PQ5A 3D44A 4JMJA 2Y67A 2BIJA 1C88A 2CM3A 2SHPA 4C12A 1KAVA 2QBPA 1XXPA 4GFVA 2PA5A 3N0AA 4I8NA 2CM2A 2ZN7A 4Z6BA 2I6IA 1XBOA 2VTDA 4YR8B 1AAXA 1OHDA 2Y66A 2H04A 2M3VA 2H4GA 2A8BA
chains in the Genus database with same CATH topology
4ZI4A 1YN9A 3S4OA 1J4XA 4DGPA 1ONZA 4QBEA 3GXHA 4RDDA 1NWEA 1P15A 3AWGA 4ICZA 3QCGA 2I6OA 3CWEA 1C87A 2PSZA 3MOZA 1U25A 1I57A 1XXVA 4JNBA 2PT0A 4OHHA 1G1GA 1X24A 5EHPA 2P4DA 2CMBA 1Q6SA 4OHLA 3S3HA 2I1YA 3U96A 4GFUA 2BV5A 2HC2A 2PBNA 4ZN5A 2Y96A 3D1OA 1PTUA 5HDEA 2CNFA 4KI9A 2CFVA 4DGXA 2HB1A 4QAPA 2QEPA 3RZ2A 3OMHA 2P6XA 1YGRA 4R0SA 2PI7A 5KA9A 1C83A 1PA1A 3V0HA 3B7OA 1C85A 2NLKA 2BGDA 2VEXA 1OEUA 4QBWA 4D3PA 4D3RA 3LJ8A 2CNHA 3EB1A 1R6HA 5KA3A 2F6WA 5KA4A 1NL9A 1OETA 4S0GA 4NYHA 4KYQA 3QCNA 1RPMA 1Q1MA 1WCHA 2I75A 2NZ6A 2R0BA 1OEMX 5KABA 1OEOX 2AZRA 1VHRA 2CM7A 4JMKA 3QCKA 4GRZA 2F6YA 2MBCA 4NX8A 2NTAA 5AWXA 2B07A 1OESA 3QCCA 1SUGA 3AWFA 4RI5A 3D42A 2I6JA 4BPCA 2QBQA 3D1QA 2B4SA 1YTNA 2FH7A 2QCTA 2HY3A 1XRIA 3EZZA 4RH5A 1T48A 1ZC0A 1ECVA 1YTSA 3I80A 3V0IA 2B3OA 1PTVA 4TVVA 5KACA 2CJZA 4R0TA 2CNEA 2HVLA 4GE2A 3F9AA 3I36A 4QUMA 2B4UA 1G1HA 2VEWA 2GWOA 3MOWA 1U26A 4IKCA 5K9VA 4HJPA 3QCFA 3F81A 4ERCA 1YWFA 2QDMA 5K22A 1NNYA 5M43A 3QKQA 3RGOA 2HNQA 4B04A 1G4WR 5KA8A 3O5XA 3QCJA 2F70A 3QCDA 1BZCA 4WTYA 4BJOA 2OOQA 2I4GA 2H4KA 4GRYA 2Q47A 3V0JA 1L8GA 1XM2A 5KA7A 2NV5A 3BM8A 3RGQA 4Y2EA 4OHEA 3ZM0A 1YFOA 1G7FA 4HJQA 4OHDA 2I6MA 1PXHA 2H4VA 3QCLA 1RXDA 3S3FA 4QAHA 2H03A 1ONYA 5LXQB 2G59A 5BZZA 4HRFA 5K9WA 2B4PA 1LARA 4J51A 2GP0A 1I9SA 3F99A 5K23A 1JLNA 2BGEA 2HC1A 3GXGA 2C46A 5MMZB 3QCMA 3H2XA 4R30A 4H1OA 4PYHA 3ZV2A 2AHSA 1D5RA 5KADA 2A3KA 4D3QA 4KYRA 1NWLA 2FJMA 2VEVA 2I3UA 3QCBA 2I4EA 3MMJA 2NT7A 1NO6A 3ZMPA 2ESBA 1WRMA 2FJNA 2B49A 3QCIA 1PH0A 3QCHA 2Q05A 1L8KA 5KA0A 5I6VA 2I3RA 4NWFA 2CNIA 3M4UA 2QBRA 4RHGA 2VEUA 2QCJA 3EU0A 1Q6PA 5J8RA 3CM3A 4H34A 2F71A 4GE6A 5KAAA 5GTJA 2ZMMA 2F46A 1C86A 1OHCA 2F6VA 2C7SA 5IBSA 1U24A 2VEYA 4MBBA 4WU2A 3V0EA 5BUGA 2RF6A 4NWGA 1C84A 2OZ5A 1BZHA 4JBCA 5EHRA 3D9CA 1Q6JA 2B4OA 5K25A 2HXPA 4RKKA 3ZMQA 3RO1A 1OHEA 3QCEA 2F6ZA 3F41A 1G4US 4Y14A 5IBMA 3ZM3A 3V0FA 2I42A 4GE5A 1JF7A 1PTYA 2J17A 1V3AA 3ZM2A 2IMGA 4YAAA 2F6FA 2I6PA 1FPZA 2Y2FA 1M3GA 2QDCA 3BLTA 3F9BA 3EAXA 3O4TA 3I7ZA 3O4UA 1LYVA 4WOHA 3O3LA 1GFYA 2WGPA 3ZM1A 2J16B 2JJDA 4GS0A 3NMEA 3SMEA 2QDPA 2CNGA 1ZCKA 2OUDA 3V0GA 1YTWA 1Q6MA 1FQ1A 4PVGA 5KA2A 3O4SA 1I9TA 1T49A 2YDUA 4AZ1A 3AWEA 1BZJA 1G7GA 2F6TA 2H02A 1PYNA 2CMCA 2CM8A 2J16A 1G1FA 3EMUA 5KA1A 3S3KA 1KAKA 3V0DA 3D1HA 1EEOA 2GJTA 1LQFA 4OHIA 2G6ZA 1ZCLA 3QKPA 2I4HA 1QZ0A 2DXPA 1PTTA 2HCMA 2OC3A 1YPTA 3BRHA 1T4JA 1PA9A 2HNPA 3S3EA 3SR9A 4RI4A 2BZLA 4GWFA 4ZRTA 1Q6TA 2QBSA 2NT2A 1MKPA 1YGUA 1WAXA 1YZ4A 3A5KA 3PS5A 1A5YA 4WU3A 4RH9A 1ZZWA 3S4EA 1NZ7A 3A5JA 1Q6NA 1QXKA 1GWZA 5K24A 5BZXA 4QUNA 4NNDA 1EENA 5BX1A 1FPRA 1OEVA 2E0TA 3BLUA 2I5XA 3OLRA 2CMAA 2PQ5A 3D44A 4JMJA 2BIJA 1C88A 2CM3A 2SHPA 1KAVA 2QBPA 1XXPA 4GFVA 2PA5A 3N0AA 4I8NA 2CM2A 2ZN7A 4Z6BA 2I6IA 1XBOA 4YR8B 1AAXA 1OHDA 2H04A 2M3VA 2H4GA 2A8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZI4 A;  1YN9 A;  3S4O A;  1J4X A;  4DGP A;  1ONZ A;  4QBE A;  3GXH A;  4RDD A;  1NWE A;  1P15 A;  3AWG A;  4ICZ A;  3QCG A;  2I6O A;  3CWE A;  1C87 A;  2PSZ A;  3MOZ A;  1U25 A;  1I57 A;  1XXV A;  4JNB A;  2PT0 A;  4OHH A;  1G1G A;  1X24 A;  5EHP A;  2P4D A;  2CMB A;  1Q6S A;  4OHL A;  3S3H A;  2I1Y A;  3U96 A;  4GFU A;  2BV5 A;  2HC2 A;  2PBN A;  4ZN5 A;  2Y96 A;  3D1O A;  1PTU A;  5HDE A;  2CNF A;  4KI9 A;  2CFV A;  4DGX A;  2HB1 A;  4QAP A;  2QEP A;  3RZ2 A;  3OMH A;  2P6X A;  1YGR A;  4R0S A;  2PI7 A;  5KA9 A;  1C83 A;  1PA1 A;  3V0H A;  3B7O A;  1C85 A;  2NLK A;  2BGD A;  2VEX A;  1OEU A;  4QBW A;  4D3P A;  4D3R A;  3LJ8 A;  2CNH A;  3EB1 A;  1R6H A;  5KA3 A;  2F6W A;  5KA4 A;  1NL9 A;  1OET A;  4S0G A;  4NYH A;  4KYQ A;  3QCN A;  1RPM A;  1Q1M A;  1WCH A;  2I75 A;  2NZ6 A;  2R0B A;  1OEM X;  5KAB A;  1OEO X;  2AZR A;  1VHR A;  2CM7 A;  4JMK A;  3QCK A;  4GRZ A;  2F6Y A;  2MBC A;  4NX8 A;  2NTA A;  5AWX A;  2B07 A;  1OES A;  3QCC A;  1SUG A;  3AWF A;  4RI5 A;  3D42 A;  2I6J A;  4BPC A;  2QBQ A;  3D1Q A;  2B4S A;  1YTN A;  2FH7 A;  2QCT A;  2HY3 A;  1XRI A;  3EZZ A;  4RH5 A;  1T48 A;  1ZC0 A;  1ECV A;  1YTS A;  3I80 A;  3V0I A;  2B3O A;  1PTV A;  4TVV A;  5KAC A;  2CJZ A;  4R0T A;  2CNE A;  2HVL A;  4GE2 A;  3F9A A;  3I36 A;  4QUM A;  2B4U A;  1G1H A;  2VEW A;  2GWO A;  3MOW A;  1U26 A;  4IKC A;  5K9V A;  4HJP A;  3QCF A;  3F81 A;  4ERC A;  1YWF A;  2QDM A;  5K22 A;  1NNY A;  5M43 A;  3QKQ A;  3RGO A;  2HNQ A;  4B04 A;  1G4W R;  5KA8 A;  3O5X A;  3QCJ A;  2F70 A;  3QCD A;  1BZC A;  4WTY A;  4BJO A;  2OOQ A;  2I4G A;  2H4K A;  4GRY A;  2Q47 A;  3V0J A;  1L8G A;  1XM2 A;  5KA7 A;  2NV5 A;  3BM8 A;  3RGQ A;  4Y2E A;  4OHE A;  3ZM0 A;  1YFO A;  1G7F A;  4HJQ A;  4OHD A;  2I6M A;  1PXH A;  2H4V A;  3QCL A;  1RXD A;  3S3F A;  4QAH A;  2H03 A;  1ONY A;  5LXQ B;  2G59 A;  5BZZ A;  4HRF A;  5K9W A;  2B4P A;  1LAR A;  4J51 A;  2GP0 A;  1I9S A;  3F99 A;  5K23 A;  1JLN A;  2BGE A;  2HC1 A;  3GXG A;  2C46 A;  5MMZ B;  3QCM A;  3H2X A;  4R30 A;  4H1O A;  4PYH A;  3ZV2 A;  2AHS A;  1D5R A;  5KAD A;  2A3K A;  4D3Q A;  4KYR A;  1NWL A;  2FJM A;  2VEV A;  2I3U A;  3QCB A;  2I4E A;  3MMJ A;  2NT7 A;  1NO6 A;  3ZMP A;  2ESB A;  1WRM A;  2FJN A;  2B49 A;  3QCI A;  1PH0 A;  3QCH A;  2Q05 A;  1L8K A;  5KA0 A;  5I6V A;  2I3R A;  4NWF A;  2CNI A;  3M4U A;  2QBR A;  4RHG A;  2VEU A;  2QCJ A;  3EU0 A;  1Q6P A;  5J8R A;  3CM3 A;  4H34 A;  2F71 A;  4GE6 A;  5KAA A;  5GTJ A;  2ZMM A;  2F46 A;  1C86 A;  1OHC A;  2F6V A;  2C7S A;  5IBS A;  1U24 A;  2VEY A;  4MBB A;  4WU2 A;  3V0E A;  5BUG A;  2RF6 A;  4NWG A;  1C84 A;  2OZ5 A;  1BZH A;  4JBC A;  5EHR A;  3D9C A;  1Q6J A;  2B4O A;  5K25 A;  2HXP A;  4RKK A;  3ZMQ A;  3RO1 A;  1OHE A;  3QCE A;  2F6Z A;  3F41 A;  1G4U S;  4Y14 A;  5IBM A;  3ZM3 A;  3V0F A;  2I42 A;  4GE5 A;  1JF7 A;  1PTY A;  2J17 A;  1V3A A;  3ZM2 A;  2IMG A;  4YAA A;  2F6F A;  2I6P A;  1FPZ A;  2Y2F A;  1M3G A;  2QDC A;  3BLT A;  3F9B A;  3EAX A;  3O4T A;  3I7Z A;  3O4U A;  1LYV A;  4WOH A;  3O3L A;  1GFY A;  2WGP A;  3ZM1 A;  2J16 B;  2JJD A;  4GS0 A;  3NME A;  3SME A;  2QDP A;  2CNG A;  1ZCK A;  2OUD A;  3V0G A;  1YTW A;  1Q6M A;  1FQ1 A;  4PVG A;  5KA2 A;  3O4S A;  1I9T A;  1T49 A;  2YDU A;  4AZ1 A;  3AWE A;  1BZJ A;  1G7G A;  2F6T A;  2H02 A;  1PYN A;  2CMC A;  2CM8 A;  2J16 A;  1G1F A;  3EMU A;  5KA1 A;  3S3K A;  1KAK A;  3V0D A;  3D1H A;  1EEO A;  2GJT A;  1LQF A;  4OHI A;  2G6Z A;  1ZCL A;  3QKP A;  2I4H A;  1QZ0 A;  2DXP A;  1PTT A;  2HCM A;  2OC3 A;  1YPT A;  3BRH A;  1T4J A;  1PA9 A;  2HNP A;  3S3E A;  3SR9 A;  4RI4 A;  2BZL A;  4GWF A;  4ZRT A;  1Q6T A;  2QBS A;  2NT2 A;  1MKP A;  1YGU A;  1WAX A;  1YZ4 A;  3A5K A;  3PS5 A;  1A5Y A;  4WU3 A;  4RH9 A;  1ZZW A;  3S4E A;  1NZ7 A;  3A5J A;  1Q6N A;  1QXK A;  1GWZ A;  5K24 A;  5BZX A;  4QUN A;  4NND A;  1EEN A;  5BX1 A;  1FPR A;  1OEV A;  2E0T A;  3BLU A;  2I5X A;  3OLR A;  2CMA A;  2PQ5 A;  3D44 A;  4JMJ A;  2BIJ A;  1C88 A;  2CM3 A;  2SHP A;  1KAV A;  2QBP A;  1XXP A;  4GFV A;  2PA5 A;  3N0A A;  4I8N A;  2CM2 A;  2ZN7 A;  4Z6B A;  2I6I A;  1XBO A;  4YR8 B;  1AAX A;  1OHD A;  2H04 A;  2M3V A;  2H4G A;  2A8B A; 
#chains in the Genus database with same CATH topology
 5A5E A;  4ZI4 A;  1YN9 A;  3S4O A;  1J4X A;  4DGP A;  1ONZ A;  4QBE A;  3GXH A;  4RDD A;  1NWE A;  1P15 A;  3N2A A;  3AWG A;  4ICZ A;  1J6U A;  3QCG A;  2I6O A;  3CWE A;  1C87 A;  2PSZ A;  3MOZ A;  1U25 A;  1I57 A;  1XXV A;  4JNB A;  2PT0 A;  4OHH A;  1G1G A;  2Y1O A;  1X24 A;  5EHP A;  2P4D A;  2CMB A;  1Q6S A;  4OHL A;  1E0D A;  3S3H A;  2I1Y A;  3U96 A;  4GFU A;  2BV5 A;  2HC2 A;  2PBN A;  4ZN5 A;  2Y96 A;  3D1O A;  1PTU A;  5HDE A;  2XJA A;  2CNF A;  4KI9 A;  2CFV A;  4DGX A;  2X5O A;  2AM1 A;  2HB1 A;  4QAP A;  2QEP A;  3RZ2 A;  3OMH A;  2P6X A;  1YGR A;  4R0S A;  1GQY A;  2PI7 A;  5KA9 A;  1C83 A;  1PA1 A;  3V0H A;  3B7O A;  1C85 A;  2NLK A;  2BGD A;  2XPC A;  2VEX A;  3ZL8 A;  1OEU A;  4QBW A;  4D3P A;  4D3R A;  3LJ8 A;  2CNH A;  3EB1 A;  1R6H A;  5KA3 A;  2F6W A;  5KA4 A;  2JFG A;  1NL9 A;  1OET A;  4S0G A;  4CVK A;  2AM2 A;  4NYH A;  4KYQ A;  3QCN A;  1RPM A;  1Q1M A;  1WCH A;  2I75 A;  2NZ6 A;  2R0B A;  1OEM X;  5KAB A;  1OEO X;  2AZR A;  1VHR A;  2CM7 A;  4JMK A;  3QCK A;  4GRZ A;  2F6Y A;  2MBC A;  4NX8 A;  2NTA A;  5AWX A;  2B07 A;  1OES A;  3QCC A;  1SUG A;  3AWF A;  4RI5 A;  2VOR A;  3D42 A;  2I6J A;  2UUP A;  4BPC A;  2QBQ A;  3D1Q A;  1O5Z A;  2B4S A;  1YTN A;  2FH7 A;  2QCT A;  2HY3 A;  1XRI A;  3EZZ A;  4RH5 A;  1T48 A;  1ZC0 A;  1ECV A;  1YTS A;  3I80 A;  3V0I A;  4QF5 A;  2B3O A;  1PTV A;  4TVV A;  5KAC A;  2CJZ A;  4R0T A;  2CNE A;  2HVL A;  4GE2 A;  3F9A A;  3I36 A;  2VOS A;  4QUM A;  2GCB A;  2B4U A;  1G1H A;  2VEW A;  2GWO A;  3MOW A;  1U26 A;  4IKC A;  5K9V A;  4HJP A;  3QCF A;  3F81 A;  2Y68 A;  4ERC A;  1YWF A;  2QDM A;  5K22 A;  3PYZ A;  1NNY A;  3HN7 A;  5M43 A;  3QKQ A;  3RGO A;  2HNQ A;  4B04 A;  1G4W R;  5KA8 A;  3O5X A;  3QCJ A;  2F70 A;  3QCD A;  1BZC A;  4WTY A;  4BJO A;  2OOQ A;  2I4G A;  2H4K A;  4GRY A;  2Q47 A;  3V0J A;  1L8G A;  1XM2 A;  4C13 A;  5KA7 A;  2NV5 A;  3BM8 A;  3RGQ A;  4Y2E A;  4OHE A;  3ZM0 A;  1YFO A;  1G7F A;  4HJQ A;  2WJP A;  4BUB A;  4OHD A;  2I6M A;  1PXH A;  2H4V A;  3QCL A;  1RXD A;  3S3F A;  4QAH A;  2H03 A;  1ONY A;  5LXQ B;  2G59 A;  2GCA A;  5BZZ A;  4HRF A;  5K9W A;  2B4P A;  1LAR A;  4J51 A;  2GP0 A;  1I9S A;  3F99 A;  1FGS A;  5K23 A;  1JLN A;  2BGE A;  2HC1 A;  4UAG A;  3GXG A;  2C46 A;  5MMZ B;  3QCM A;  3H2X A;  4R30 A;  4H1O A;  4PYH A;  3ZV2 A;  2AHS A;  1D5R A;  5KAD A;  1GG4 A;  3ZM5 A;  2A3K A;  4D3Q A;  4KYR A;  1NWL A;  4ZIY A;  2FJM A;  2VEV A;  2I3U A;  3QCB A;  2I4E A;  3MMJ A;  2NT7 A;  1NO6 A;  3ZMP A;  2ESB A;  1WRM A;  2FJN A;  2B49 A;  3QCI A;  3UAG A;  1PH0 A;  3QCH A;  2Q05 A;  1L8K A;  5KA0 A;  5I6V A;  2I3R A;  4NWF A;  2CNI A;  3M4U A;  2QBR A;  4RHG A;  2VEU A;  2QCJ A;  3EU0 A;  1Q6P A;  5J8R A;  1JBV A;  3CM3 A;  4H34 A;  2F71 A;  4GE6 A;  4QDI A;  5GTJ A;  5KAA A;  2ZMM A;  2F46 A;  1C86 A;  1OHC A;  2F6V A;  2C7S A;  5IBS A;  1U24 A;  2VEY A;  1JBW A;  4MBB A;  4WU2 A;  3V0E A;  5BUG A;  3NRS A;  2RF6 A;  4NWG A;  1C84 A;  2OZ5 A;  1BZH A;  4JBC A;  5EHR A;  3D9C A;  1Q6J A;  2B4O A;  5K25 A;  2HXP A;  4RKK A;  3ZMQ A;  3RO1 A;  1OHE A;  3QCE A;  2F6Z A;  3F41 A;  1EEH A;  1G4U S;  2VTE A;  4Y14 A;  5IBM A;  1P3D A;  3ZM3 A;  3V0F A;  2I42 A;  4GE5 A;  1JF7 A;  1PTY A;  2J17 A;  1V3A A;  3ZM2 A;  2IMG A;  5A5F A;  4YAA A;  4CVL A;  2F6F A;  2I6P A;  1FPZ A;  2Y2F A;  1M3G A;  2QDC A;  3BLT A;  1E8C A;  1W78 A;  3F9B A;  3EAX A;  3O4T A;  3I7Z A;  3O4U A;  1LYV A;  4WOH A;  3O3L A;  1GFY A;  2WGP A;  3ZM1 A;  2J16 B;  2JJD A;  4GS0 A;  4BUC A;  3NME A;  2UAG A;  3SME A;  2JFF A;  1W7K A;  2QDP A;  2CNG A;  1ZCK A;  2OUD A;  3V0G A;  1YTW A;  1Q6M A;  3LK7 A;  1FQ1 A;  3ZM6 A;  4PVG A;  3QCZ A;  5KA2 A;  3O4S A;  1I9T A;  1T49 A;  2YDU A;  4AZ1 A;  3AWE A;  1BZJ A;  1UAG A;  1G7G A;  2F6T A;  2H02 A;  1PYN A;  2CMC A;  2CM8 A;  2JFH A;  2J16 A;  1G1F A;  3EMU A;  5KA1 A;  3S3K A;  1KAK A;  3V0D A;  3D1H A;  1EEO A;  2GJT A;  1LQF A;  4OHI A;  1GQQ A;  1ZCL A;  2G6Z A;  3QKP A;  2I4H A;  1QZ0 A;  2DXP A;  1PTT A;  2HCM A;  2OC3 A;  1YPT A;  3BRH A;  1T4J A;  1PA9 A;  1P31 A;  2HNP A;  4CVM A;  3S3E A;  3SR9 A;  4RI4 A;  2BZL A;  4GWF A;  4ZRT A;  1Q6T A;  2QBS A;  2NT2 A;  1MKP A;  1YGU A;  1WAX A;  1YZ4 A;  3A5K A;  2UUO A;  3PS5 A;  2F00 A;  3MVN A;  1A5Y A;  4WU3 A;  4RH9 A;  1ZZW A;  3S4E A;  2GC6 A;  2GC5 A;  1NZ7 A;  3A5J A;  1Q6N A;  1QXK A;  1GWZ A;  5K24 A;  5BZX A;  4HV4 A;  4QUN A;  4NND A;  1EEN A;  5BX1 A;  1FPR A;  1OEV A;  2E0T A;  2WTZ A;  3BLU A;  2I5X A;  3OLR A;  2CMA A;  2PQ5 A;  3D44 A;  4JMJ A;  2Y67 A;  2BIJ A;  1C88 A;  2CM3 A;  2SHP A;  4C12 A;  1KAV A;  2QBP A;  1XXP A;  4GFV A;  2PA5 A;  3N0A A;  4I8N A;  2CM2 A;  2ZN7 A;  4Z6B A;  2I6I A;  1XBO A;  2VTD A;  4YR8 B;  1AAX A;  1OHD A;  2Y66 A;  2H04 A;  2M3V A;  2H4G A;  2A8B A; 
#chains in the Genus database with same CATH homology
 4ZI4 A;  1YN9 A;  3S4O A;  1J4X A;  4DGP A;  1ONZ A;  4QBE A;  3GXH A;  4RDD A;  1NWE A;  1P15 A;  3AWG A;  4ICZ A;  3QCG A;  2I6O A;  3CWE A;  1C87 A;  2PSZ A;  3MOZ A;  1U25 A;  1I57 A;  1XXV A;  4JNB A;  2PT0 A;  4OHH A;  1G1G A;  1X24 A;  5EHP A;  2P4D A;  2CMB A;  1Q6S A;  4OHL A;  3S3H A;  2I1Y A;  3U96 A;  4GFU A;  2BV5 A;  2HC2 A;  2PBN A;  4ZN5 A;  2Y96 A;  3D1O A;  1PTU A;  5HDE A;  2CNF A;  4KI9 A;  2CFV A;  4DGX A;  2HB1 A;  4QAP A;  2QEP A;  3RZ2 A;  3OMH A;  2P6X A;  1YGR A;  4R0S A;  2PI7 A;  5KA9 A;  1C83 A;  1PA1 A;  3V0H A;  3B7O A;  1C85 A;  2NLK A;  2BGD A;  2VEX A;  1OEU A;  4QBW A;  4D3P A;  4D3R A;  3LJ8 A;  2CNH A;  3EB1 A;  1R6H A;  5KA3 A;  2F6W A;  5KA4 A;  1NL9 A;  1OET A;  4S0G A;  4NYH A;  4KYQ A;  3QCN A;  1RPM A;  1Q1M A;  1WCH A;  2I75 A;  2NZ6 A;  2R0B A;  1OEM X;  5KAB A;  1OEO X;  2AZR A;  1VHR A;  2CM7 A;  4JMK A;  3QCK A;  4GRZ A;  2F6Y A;  2MBC A;  4NX8 A;  2NTA A;  5AWX A;  2B07 A;  1OES A;  3QCC A;  1SUG A;  3AWF A;  4RI5 A;  3D42 A;  2I6J A;  4BPC A;  2QBQ A;  3D1Q A;  2B4S A;  1YTN A;  2FH7 A;  2QCT A;  2HY3 A;  1XRI A;  3EZZ A;  4RH5 A;  1T48 A;  1ZC0 A;  1ECV A;  1YTS A;  3I80 A;  3V0I A;  2B3O A;  1PTV A;  4TVV A;  5KAC A;  2CJZ A;  4R0T A;  2CNE A;  2HVL A;  4GE2 A;  3F9A A;  3I36 A;  4QUM A;  2B4U A;  1G1H A;  2VEW A;  2GWO A;  3MOW A;  1U26 A;  4IKC A;  5K9V A;  4HJP A;  3QCF A;  3F81 A;  4ERC A;  1YWF A;  2QDM A;  5K22 A;  1NNY A;  5M43 A;  3QKQ A;  3RGO A;  2HNQ A;  4B04 A;  1G4W R;  5KA8 A;  3O5X A;  3QCJ A;  2F70 A;  3QCD A;  1BZC A;  4WTY A;  4BJO A;  2OOQ A;  2I4G A;  2H4K A;  4GRY A;  2Q47 A;  3V0J A;  1L8G A;  1XM2 A;  5KA7 A;  2NV5 A;  3BM8 A;  3RGQ A;  4Y2E A;  4OHE A;  3ZM0 A;  1YFO A;  1G7F A;  4HJQ A;  4OHD A;  2I6M A;  1PXH A;  2H4V A;  3QCL A;  1RXD A;  3S3F A;  4QAH A;  2H03 A;  1ONY A;  5LXQ B;  2G59 A;  5BZZ A;  4HRF A;  5K9W A;  2B4P A;  1LAR A;  4J51 A;  2GP0 A;  1I9S A;  3F99 A;  5K23 A;  1JLN A;  2BGE A;  2HC1 A;  3GXG A;  2C46 A;  5MMZ B;  3QCM A;  3H2X A;  4R30 A;  4H1O A;  4PYH A;  3ZV2 A;  2AHS A;  1D5R A;  5KAD A;  2A3K A;  4D3Q A;  4KYR A;  1NWL A;  2FJM A;  2VEV A;  2I3U A;  3QCB A;  2I4E A;  3MMJ A;  2NT7 A;  1NO6 A;  3ZMP A;  2ESB A;  1WRM A;  2FJN A;  2B49 A;  3QCI A;  1PH0 A;  3QCH A;  2Q05 A;  1L8K A;  5KA0 A;  5I6V A;  2I3R A;  4NWF A;  2CNI A;  3M4U A;  2QBR A;  4RHG A;  2VEU A;  2QCJ A;  3EU0 A;  1Q6P A;  5J8R A;  3CM3 A;  4H34 A;  2F71 A;  4GE6 A;  5KAA A;  5GTJ A;  2ZMM A;  2F46 A;  1C86 A;  1OHC A;  2F6V A;  2C7S A;  5IBS A;  1U24 A;  2VEY A;  4MBB A;  4WU2 A;  3V0E A;  5BUG A;  2RF6 A;  4NWG A;  1C84 A;  2OZ5 A;  1BZH A;  4JBC A;  5EHR A;  3D9C A;  1Q6J A;  2B4O A;  5K25 A;  2HXP A;  4RKK A;  3ZMQ A;  3RO1 A;  1OHE A;  3QCE A;  2F6Z A;  3F41 A;  1G4U S;  4Y14 A;  5IBM A;  3ZM3 A;  3V0F A;  2I42 A;  4GE5 A;  1JF7 A;  1PTY A;  2J17 A;  1V3A A;  3ZM2 A;  2IMG A;  4YAA A;  2F6F A;  2I6P A;  1FPZ A;  2Y2F A;  1M3G A;  2QDC A;  3BLT A;  3F9B A;  3EAX A;  3O4T A;  3I7Z A;  3O4U A;  1LYV A;  4WOH A;  3O3L A;  1GFY A;  2WGP A;  3ZM1 A;  2J16 B;  2JJD A;  4GS0 A;  3NME A;  3SME A;  2QDP A;  2CNG A;  1ZCK A;  2OUD A;  3V0G A;  1YTW A;  1Q6M A;  1FQ1 A;  4PVG A;  5KA2 A;  3O4S A;  1I9T A;  1T49 A;  2YDU A;  4AZ1 A;  3AWE A;  1BZJ A;  1G7G A;  2F6T A;  2H02 A;  1PYN A;  2CMC A;  2CM8 A;  2J16 A;  1G1F A;  3EMU A;  5KA1 A;  3S3K A;  1KAK A;  3V0D A;  3D1H A;  1EEO A;  2GJT A;  1LQF A;  4OHI A;  2G6Z A;  1ZCL A;  3QKP A;  2I4H A;  1QZ0 A;  2DXP A;  1PTT A;  2HCM A;  2OC3 A;  1YPT A;  3BRH A;  1T4J A;  1PA9 A;  2HNP A;  3S3E A;  3SR9 A;  4RI4 A;  2BZL A;  4GWF A;  4ZRT A;  1Q6T A;  2QBS A;  2NT2 A;  1MKP A;  1YGU A;  1WAX A;  1YZ4 A;  3A5K A;  3PS5 A;  1A5Y A;  4WU3 A;  4RH9 A;  1ZZW A;  3S4E A;  1NZ7 A;  3A5J A;  1Q6N A;  1QXK A;  1GWZ A;  5K24 A;  5BZX A;  4QUN A;  4NND A;  1EEN A;  5BX1 A;  1FPR A;  1OEV A;  2E0T A;  3BLU A;  2I5X A;  3OLR A;  2CMA A;  2PQ5 A;  3D44 A;  4JMJ A;  2BIJ A;  1C88 A;  2CM3 A;  2SHP A;  1KAV A;  2QBP A;  1XXP A;  4GFV A;  2PA5 A;  3N0A A;  4I8N A;  2CM2 A;  2ZN7 A;  4Z6B A;  2I6I A;  1XBO A;  4YR8 B;  1AAX A;  1OHD A;  2H04 A;  2M3V A;  2H4G A;  2A8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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