3B7OA

Crystal structure of the human tyrosine phosphatase shp2 (ptpn11) with an accessible active site
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
283
structure length
272
Chain Sequence
GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Large-scale structural analysis of the classical human protein tyrosine phosphatome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 96
structure length 272
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3b7oA00
4I8NA 3F81A 3NMEA 1Q6NA 3A5KA 1FPRA 1G1FA 2I6IA 4D3RA 1C85A 1RXDA 4GFUA 4JNBA 2RF6A 2BIJA 5KA3A 2J16A 5KADA 2QBRA 2I4EA 2Y2FA 5K25A 5EHRA 2WGPA 4OHLA 1YGUA 1OHDA 2NTAA 5K23A 4GE6A 1FPZA 2HY3A 4D3PA 3S3FA 1Q6PA 1ONZA 2H4KA 4WTYA 1U26A 2HC1A 1G4US 3EB1A 3F9AA 1LYVA 4GWFA 2B07A 1PYNA 3QCJA 5AWXA 4NWFA 4QAPA 4KI9A 4BPCA 5K9WA 3RZ2A 2F6YA 1T4JA 2OUDA 5EHPA 2FJNA 2F6TA 1T48A 4GE5A 3F41A 4JBCA 2HNPA 2YDUA 2HXPA 2GWOA 2J16B 1WRMA 4NX8A 4DGPA 2DXPA 4MBBA 3QCIA 3V0HA 2OZ5A 3D9CA 3AWEA 5I6VA 1OHCA 3O4SA 4H1OA 2B4UA 1G1GA 2CMBA 1Q6MA 3EZZA 5MMZB 3O4UA 4YR8B 1YTSA 1XBOA 1OEMX 2CM7A 5BZXA 3SMEA 5KA8A 3MOZA 1NWEA 2I5XA 1P15A 2GP0A 4JMJA 3D1HA 4WOHA 1AAXA 1YWFA 4QUNA 4QBEA 1U24A 1PA1A 5BX1A 5LXQB 4J51A 2ZN7A 3BRHA 4DGXA 2J17A 3M4UA 5GTJA 2M3VA 1LQFA 1WCHA 2F46A 5K22A 3ZM3A 2CNGA 4GRZA 3B7OA 2NLKA 4RH5A 3QCMA 5M43A 1VHRA 3RGOA 3QCEA 4H34A 4HJPA 1YPTA 2CM8A 3A5JA 1WAXA 2QBPA 4GRYA 2B4SA 2C7SA 1PH0A 2PA5A 1SUGA 3F9BA 2CNIA 2B49A 2QDCA 2VEWA 3O5XA 3QCCA 2VEXA 5KA9A 2B3OA 2IMGA 1BZJA 3ZM2A 3EU0A 3MOWA 2I75A 2CFVA 1OHEA 3SR9A 2BZLA 2SHPA 3GXHA 3QKPA 1OEUA 2ESBA 2H02A 4RKKA 4AZ1A 2HCMA 2AHSA 4RH9A 3QCDA 3ZM1A 1NO6A 4WU2A 4TVVA 4RI4A 2PT0A 3BM8A 2CMAA 5J8RA 3V0GA 3S3HA 2I42A 1Q6JA 1YTWA 2OOQA 4RDDA 1A5YA 3EAXA 4KYQA 3U96A 3BLUA 2I6PA 2QEPA 4GE2A 2F6WA 1G7FA 1QXKA 2H03A 2BGDA 1Q6SA 1NWLA 2A3KA 4RI5A 2F71A 3GXGA 2PBNA 3F99A 2CMCA 1YZ4A 3AWGA 4OHIA 3H2XA 2CNFA 1ZC0A 1G1HA 2HC2A 1YN9A 1M3GA 4KYRA 1GFYA 2A8BA 2B4PA 2NT7A 1XRIA 3ZV2A 1Q1MA 4YAAA 3QCFA 2BGEA 1PTYA 2HB1A 1C83A 2FH7A 2HVLA 1YGRA 2CM2A 3I7ZA 2PSZA 4S0GA 1J4XA 2GJTA 1C87A 1C88A 3S3EA 2QBSA 3ZMPA 3CM3A 3N0AA 2CJZA 1JF7A 2VEVA 4HJQA 2F6ZA 4R0TA 2I1YA 3BLTA 3ZM0A 1T49A 2CNHA 2PQ5A 2MBCA 4GFVA 1PA9A 1KAKA 2F70A 3V0EA 3D44A 3O3LA 5KA4A 5KA7A 4R0SA 2VEUA 2QBQA 5BZZA 1RPMA 4BJOA 2NV5A 1OESA 1ZCKA 4QUMA 2NT2A 3ZMQA 2G6ZA 2QCJA 5K24A 4D3QA 4PYHA 2C46A 4PVGA 1L8GA 4QBWA 2G59A 3V0DA 2OC3A 2QCTA 2R0BA 2Q47A 1PTVA 3O4TA 1NZ7A 2NZ6A 1X24A 3OLRA 1PXHA 2F6VA 1BZHA 1U25A 3EMUA 2I4HA 4R30A 3QCNA 1D5RA 4JMKA 4NNDA 3QKQA 4ZI4A 3QCGA 3I36A 1I9TA 2I6MA 1ECVA 2P4DA 5KA2A 4ERCA 3D1QA 1EEOA 5KACA 2H4GA 1G7GA 2PI7A 1OEVA 2HNQA 2QDMA 1V3AA 1PTUA 1XM2A 5K9VA 1ZCLA 1G4WR 1JLNA 2AZRA 3D1OA 1NL9A 4WU3A 3V0JA 4B04A 4RHGA 4ZRTA 2QDPA 4OHDA 4HRFA 2BV5A 4Y2EA 1C84A 2FJMA 3D42A 3V0IA 1OEOX 1XXPA 5KABA 3QCHA 4OHEA 2P6XA 3CWEA 1I57A 4ICZA 5KA0A 2CNEA 1QZ0A 1ZZWA 2F6FA 4OHHA 3S4EA 2CM3A 2H04A 3S4OA 1PTTA 4NYHA 1L8KA 2I6JA 3I80A 1I9SA 3PS5A 2JJDA 1EENA 1C86A 1Q6TA 3RO1A 2B4OA 1ONYA 1GWZA 1LARA 1R6HA 4NWGA 2I3UA 4Y14A 3S3KA 2H4VA 1NNYA 4ZN5A 1YTNA 3OMHA 2ZMMA 3QCBA 5IBMA 3V0FA 1FQ1A 1OETA 4Z6BA 5KA1A 4QAHA 2Q05A 1YFOA 2VEYA 3LJ8A 4GS0A 2E0TA 3AWFA 1KAVA 2I3RA 2Y96A 4IKCA 5IBSA 5KAAA 3MMJA 1XXVA 5BUGA 2I4GA 1BZCA 5HDEA 3RGQA 2I6OA 3QCLA 1MKPA 3QCKA
chains in the Genus database with same CATH superfamily
4I8NA 3F81A 2F00A 3NMEA 1Q6NA 3A5KA 1FPRA 1G1FA 2I6IA 4D3RA 1C85A 1RXDA 4GFUA 4JNBA 2RF6A 2BIJA 4UAGA 5KA3A 2J16A 5KADA 2GC5A 2QBRA 2I4EA 2AM1A 2Y2FA 5K25A 5EHRA 2WGPA 4OHLA 1YGUA 1OHDA 2NTAA 5K23A 4GE6A 1FPZA 2HY3A 4D3PA 3S3FA 1Q6PA 1ONZA 2H4KA 2JFGA 2GC6A 4WTYA 1U26A 2HC1A 1G4US 3EB1A 3F9AA 1LYVA 4GWFA 4QDIA 2B07A 1PYNA 3QCJA 5AWXA 2XJAA 4NWFA 4QAPA 2Y67A 4KI9A 4BPCA 5K9WA 3RZ2A 2F6YA 1T4JA 2OUDA 5EHPA 2FJNA 2F6TA 1T48A 4GE5A 3F41A 4JBCA 2HNPA 2YDUA 2HXPA 2GWOA 2J16B 1WRMA 4NX8A 3N2AA 4DGPA 2DXPA 4MBBA 3QCIA 2X5OA 2VORA 4BUCA 3V0HA 2OZ5A 3D9CA 3AWEA 5I6VA 1OHCA 1J6UA 3O4SA 4H1OA 2B4UA 1G1GA 2CMBA 1Q6MA 3EZZA 4HV4A 5MMZB 3O4UA 4YR8B 1YTSA 1XBOA 3UAGA 2JFHA 1OEMX 2CM7A 5BZXA 3SMEA 5KA8A 3MOZA 1NWEA 2I5XA 1P15A 2GP0A 4JMJA 3D1HA 4WOHA 1AAXA 2WJPA 1YWFA 3NRSA 4QUNA 4QBEA 1U24A 1PA1A 1EEHA 5BX1A 5LXQB 4J51A 3MVNA 2ZN7A 3BRHA 4DGXA 3ZL8A 2J17A 3ZM6A 3M4UA 5GTJA 2M3VA 1LQFA 1WCHA 2F46A 1P31A 2Y1OA 5K22A 3ZM3A 2CNGA 4GRZA 3B7OA 2NLKA 4RH5A 3QCMA 2WTZA 2VOSA 5M43A 1VHRA 3RGOA 3QCEA 4H34A 4ZIYA 4HJPA 1YPTA 2CM8A 3A5JA 1WAXA 2QBPA 4GRYA 2UUPA 2B4SA 4CVMA 2C7SA 1PH0A 2PA5A 1SUGA 2VTEA 3F9BA 2CNIA 2B49A 2QDCA 2VEWA 3O5XA 3QCCA 2VEXA 5KA9A 2B3OA 2IMGA 4QF5A 1BZJA 2UUOA 3ZM2A 2UAGA 3EU0A 3MOWA 2I75A 2CFVA 1OHEA 3SR9A 2BZLA 2SHPA 3GXHA 3QKPA 1OEUA 1GQQA 2ESBA 2H02A 4RKKA 4AZ1A 1FGSA 2HCMA 2AHSA 4RH9A 3QCDA 3ZM1A 1NO6A 3ZM5A 4WU2A 4TVVA 4RI4A 2PT0A 3BM8A 2CMAA 5J8RA 4BUBA 3V0GA 1P3DA 3S3HA 2I42A 1Q6JA 1YTWA 2OOQA 1E8CA 4RDDA 1A5YA 3EAXA 4KYQA 3U96A 3BLUA 2I6PA 2QEPA 4GE2A 2F6WA 1G7FA 1QXKA 2H03A 2BGDA 1Q6SA 1NWLA 2A3KA 4RI5A 2F71A 3GXGA 4CVLA 2PBNA 3F99A 2CMCA 1YZ4A 3AWGA 4OHIA 3H2XA 2CNFA 3PYZA 1ZC0A 1G1HA 2HC2A 1YN9A 5A5FA 1M3GA 4KYRA 1GFYA 2A8BA 2B4PA 2NT7A 1XRIA 3ZV2A 1Q1MA 4YAAA 3QCFA 2BGEA 1PTYA 2HB1A 1C83A 2FH7A 2HVLA 1YGRA 2CM2A 3I7ZA 2PSZA 4S0GA 1UAGA 4CVKA 1J4XA 2GJTA 1C87A 1C88A 4C12A 3S3EA 2Y68A 2QBSA 3ZMPA 1JBWA 1W7KA 3CM3A 3N0AA 2CJZA 1JF7A 2VEVA 4HJQA 2F6ZA 4R0TA 2I1YA 3BLTA 3ZM0A 1T49A 2CNHA 2PQ5A 2MBCA 4GFVA 1PA9A 1KAKA 2F70A 3V0EA 3D44A 3O3LA 5KA4A 5KA7A 4R0SA 2VEUA 2QBQA 5BZZA 1RPMA 4BJOA 2NV5A 1OESA 1ZCKA 4QUMA 2NT2A 1O5ZA 3ZMQA 2G6ZA 2QCJA 5K24A 4D3QA 4PYHA 2C46A 1GG4A 5A5EA 4PVGA 1L8GA 4QBWA 2G59A 3V0DA 2OC3A 2QCTA 2R0BA 2Q47A 1PTVA 3O4TA 1NZ7A 2NZ6A 1X24A 3OLRA 1PXHA 2F6VA 1BZHA 1U25A 3EMUA 2I4HA 4R30A 3QCNA 1D5RA 4JMKA 4NNDA 3QKQA 4ZI4A 2GCBA 3QCGA 3I36A 3QCZA 1I9TA 2I6MA 1ECVA 2VTDA 2P4DA 5KA2A 4ERCA 3D1QA 1E0DA 1EEOA 2JFFA 5KACA 2H4GA 1G7GA 2PI7A 1OEVA 2HNQA 2QDMA 1V3AA 1PTUA 1XM2A 5K9VA 1ZCLA 1G4WR 1JLNA 2AZRA 3D1OA 1NL9A 4WU3A 3V0JA 3HN7A 4B04A 4RHGA 4ZRTA 2GCAA 2QDPA 4OHDA 4HRFA 2BV5A 4Y2EA 1C84A 2FJMA 3D42A 3V0IA 1OEOX 1XXPA 5KABA 3QCHA 4OHEA 2P6XA 3CWEA 1I57A 4ICZA 5KA0A 2CNEA 1QZ0A 1ZZWA 2F6FA 4OHHA 3S4EA 2CM3A 2H04A 3S4OA 1PTTA 4NYHA 1L8KA 2I6JA 3I80A 1I9SA 2XPCA 3PS5A 2JJDA 1EENA 1C86A 1Q6TA 3RO1A 2B4OA 1ONYA 1GWZA 1LARA 1W78A 1R6HA 4NWGA 4C13A 2I3UA 4Y14A 3S3KA 2H4VA 1NNYA 1GQYA 4ZN5A 1YTNA 3OMHA 2ZMMA 3QCBA 5IBMA 3V0FA 1FQ1A 1OETA 4Z6BA 5KA1A 4QAHA 2Q05A 1YFOA 2VEYA 3LJ8A 4GS0A 3LK7A 2E0TA 3AWFA 1KAVA 2I3RA 2Y96A 4IKCA 5IBSA 2AM2A 5KAAA 3MMJA 1XXVA 5BUGA 1JBVA 2I4GA 1BZCA 5HDEA 3RGQA 2I6OA 3QCLA 1MKPA 3QCKA 2Y66A
chains in the Genus database with same CATH topology
4I8NA 3F81A 3NMEA 1Q6NA 3A5KA 1FPRA 1G1FA 2I6IA 4D3RA 1C85A 1RXDA 4GFUA 4JNBA 2RF6A 2BIJA 5KA3A 2J16A 5KADA 2QBRA 2I4EA 2Y2FA 5K25A 5EHRA 2WGPA 4OHLA 1YGUA 1OHDA 2NTAA 5K23A 4GE6A 1FPZA 2HY3A 4D3PA 3S3FA 1Q6PA 1ONZA 2H4KA 4WTYA 1U26A 2HC1A 1G4US 3EB1A 3F9AA 1LYVA 4GWFA 2B07A 1PYNA 3QCJA 5AWXA 4NWFA 4QAPA 4KI9A 4BPCA 5K9WA 3RZ2A 2F6YA 1T4JA 2OUDA 5EHPA 2FJNA 2F6TA 1T48A 4GE5A 3F41A 4JBCA 2HNPA 2YDUA 2HXPA 2GWOA 2J16B 1WRMA 4NX8A 4DGPA 2DXPA 4MBBA 3QCIA 3V0HA 2OZ5A 3D9CA 3AWEA 5I6VA 1OHCA 3O4SA 4H1OA 2B4UA 1G1GA 2CMBA 1Q6MA 3EZZA 5MMZB 3O4UA 4YR8B 1YTSA 1XBOA 1OEMX 2CM7A 5BZXA 3SMEA 5KA8A 3MOZA 1NWEA 2I5XA 1P15A 2GP0A 4JMJA 3D1HA 4WOHA 1AAXA 1YWFA 4QUNA 4QBEA 1U24A 1PA1A 5BX1A 5LXQB 4J51A 2ZN7A 3BRHA 4DGXA 2J17A 3M4UA 5GTJA 2M3VA 1LQFA 1WCHA 2F46A 5K22A 3ZM3A 2CNGA 4GRZA 3B7OA 2NLKA 4RH5A 3QCMA 5M43A 1VHRA 3RGOA 3QCEA 4H34A 4HJPA 1YPTA 2CM8A 3A5JA 1WAXA 2QBPA 4GRYA 2B4SA 2C7SA 1PH0A 2PA5A 1SUGA 3F9BA 2CNIA 2B49A 2QDCA 2VEWA 3O5XA 3QCCA 2VEXA 5KA9A 2B3OA 2IMGA 1BZJA 3ZM2A 3EU0A 3MOWA 2I75A 2CFVA 1OHEA 3SR9A 2BZLA 2SHPA 3GXHA 3QKPA 1OEUA 2ESBA 2H02A 4RKKA 4AZ1A 2HCMA 2AHSA 4RH9A 3QCDA 3ZM1A 1NO6A 4WU2A 4TVVA 4RI4A 2PT0A 3BM8A 2CMAA 5J8RA 3V0GA 3S3HA 2I42A 1Q6JA 1YTWA 2OOQA 4RDDA 1A5YA 3EAXA 4KYQA 3U96A 3BLUA 2I6PA 2QEPA 4GE2A 2F6WA 1G7FA 1QXKA 2H03A 2BGDA 1Q6SA 1NWLA 2A3KA 4RI5A 2F71A 3GXGA 2PBNA 3F99A 2CMCA 1YZ4A 3AWGA 4OHIA 3H2XA 2CNFA 1ZC0A 1G1HA 2HC2A 1YN9A 1M3GA 4KYRA 1GFYA 2A8BA 2B4PA 2NT7A 1XRIA 3ZV2A 1Q1MA 4YAAA 3QCFA 2BGEA 1PTYA 2HB1A 1C83A 2FH7A 2HVLA 1YGRA 2CM2A 3I7ZA 2PSZA 4S0GA 1J4XA 2GJTA 1C87A 1C88A 3S3EA 2QBSA 3ZMPA 3CM3A 3N0AA 2CJZA 1JF7A 2VEVA 4HJQA 2F6ZA 4R0TA 2I1YA 3BLTA 3ZM0A 1T49A 2CNHA 2PQ5A 2MBCA 4GFVA 1PA9A 1KAKA 2F70A 3V0EA 3D44A 3O3LA 5KA4A 5KA7A 4R0SA 2VEUA 2QBQA 5BZZA 1RPMA 4BJOA 2NV5A 1OESA 1ZCKA 4QUMA 2NT2A 3ZMQA 2G6ZA 2QCJA 5K24A 4D3QA 4PYHA 2C46A 4PVGA 1L8GA 4QBWA 2G59A 3V0DA 2OC3A 2QCTA 2R0BA 2Q47A 1PTVA 3O4TA 1NZ7A 2NZ6A 1X24A 3OLRA 1PXHA 2F6VA 1BZHA 1U25A 3EMUA 2I4HA 4R30A 3QCNA 1D5RA 4JMKA 4NNDA 3QKQA 4ZI4A 3QCGA 3I36A 1I9TA 2I6MA 1ECVA 2P4DA 5KA2A 4ERCA 3D1QA 1EEOA 5KACA 2H4GA 1G7GA 2PI7A 1OEVA 2HNQA 2QDMA 1V3AA 1PTUA 1XM2A 5K9VA 1ZCLA 1G4WR 1JLNA 2AZRA 3D1OA 1NL9A 4WU3A 3V0JA 4B04A 4RHGA 4ZRTA 2QDPA 4OHDA 4HRFA 2BV5A 4Y2EA 1C84A 2FJMA 3D42A 3V0IA 1OEOX 1XXPA 5KABA 3QCHA 4OHEA 2P6XA 3CWEA 1I57A 4ICZA 5KA0A 2CNEA 1QZ0A 1ZZWA 2F6FA 4OHHA 3S4EA 2CM3A 2H04A 3S4OA 1PTTA 4NYHA 1L8KA 2I6JA 3I80A 1I9SA 3PS5A 2JJDA 1EENA 1C86A 1Q6TA 3RO1A 2B4OA 1ONYA 1GWZA 1LARA 1R6HA 4NWGA 2I3UA 4Y14A 3S3KA 2H4VA 1NNYA 4ZN5A 1YTNA 3OMHA 2ZMMA 3QCBA 5IBMA 3V0FA 1FQ1A 1OETA 4Z6BA 5KA1A 4QAHA 2Q05A 1YFOA 2VEYA 3LJ8A 4GS0A 2E0TA 3AWFA 1KAVA 2I3RA 2Y96A 4IKCA 5IBSA 5KAAA 3MMJA 1XXVA 5BUGA 2I4GA 1BZCA 5HDEA 3RGQA 2I6OA 3QCLA 1MKPA 3QCKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I8N A;  3F81 A;  3NME A;  1Q6N A;  3A5K A;  1FPR A;  1G1F A;  2I6I A;  4D3R A;  1C85 A;  1RXD A;  4GFU A;  4JNB A;  2RF6 A;  2BIJ A;  5KA3 A;  2J16 A;  5KAD A;  2QBR A;  2I4E A;  2Y2F A;  5K25 A;  5EHR A;  2WGP A;  4OHL A;  1YGU A;  1OHD A;  2NTA A;  5K23 A;  4GE6 A;  1FPZ A;  2HY3 A;  4D3P A;  3S3F A;  1Q6P A;  1ONZ A;  2H4K A;  4WTY A;  1U26 A;  2HC1 A;  1G4U S;  3EB1 A;  3F9A A;  1LYV A;  4GWF A;  2B07 A;  1PYN A;  3QCJ A;  5AWX A;  4NWF A;  4QAP A;  4KI9 A;  4BPC A;  5K9W A;  3RZ2 A;  2F6Y A;  1T4J A;  2OUD A;  5EHP A;  2FJN A;  2F6T A;  1T48 A;  4GE5 A;  3F41 A;  4JBC A;  2HNP A;  2YDU A;  2HXP A;  2GWO A;  2J16 B;  1WRM A;  4NX8 A;  4DGP A;  2DXP A;  4MBB A;  3QCI A;  3V0H A;  2OZ5 A;  3D9C A;  3AWE A;  5I6V A;  1OHC A;  3O4S A;  4H1O A;  2B4U A;  1G1G A;  2CMB A;  1Q6M A;  3EZZ A;  5MMZ B;  3O4U A;  4YR8 B;  1YTS A;  1XBO A;  1OEM X;  2CM7 A;  5BZX A;  3SME A;  5KA8 A;  3MOZ A;  1NWE A;  2I5X A;  1P15 A;  2GP0 A;  4JMJ A;  3D1H A;  4WOH A;  1AAX A;  1YWF A;  4QUN A;  4QBE A;  1U24 A;  1PA1 A;  5BX1 A;  5LXQ B;  4J51 A;  2ZN7 A;  3BRH A;  4DGX A;  2J17 A;  3M4U A;  5GTJ A;  2M3V A;  1LQF A;  1WCH A;  2F46 A;  5K22 A;  3ZM3 A;  2CNG A;  4GRZ A;  3B7O A;  2NLK A;  4RH5 A;  3QCM A;  5M43 A;  1VHR A;  3RGO A;  3QCE A;  4H34 A;  4HJP A;  1YPT A;  2CM8 A;  3A5J A;  1WAX A;  2QBP A;  4GRY A;  2B4S A;  2C7S A;  1PH0 A;  2PA5 A;  1SUG A;  3F9B A;  2CNI A;  2B49 A;  2QDC A;  2VEW A;  3O5X A;  3QCC A;  2VEX A;  5KA9 A;  2B3O A;  2IMG A;  1BZJ A;  3ZM2 A;  3EU0 A;  3MOW A;  2I75 A;  2CFV A;  1OHE A;  3SR9 A;  2BZL A;  2SHP A;  3GXH A;  3QKP A;  1OEU A;  2ESB A;  2H02 A;  4RKK A;  4AZ1 A;  2HCM A;  2AHS A;  4RH9 A;  3QCD A;  3ZM1 A;  1NO6 A;  4WU2 A;  4TVV A;  4RI4 A;  2PT0 A;  3BM8 A;  2CMA A;  5J8R A;  3V0G A;  3S3H A;  2I42 A;  1Q6J A;  1YTW A;  2OOQ A;  4RDD A;  1A5Y A;  3EAX A;  4KYQ A;  3U96 A;  3BLU A;  2I6P A;  2QEP A;  4GE2 A;  2F6W A;  1G7F A;  1QXK A;  2H03 A;  2BGD A;  1Q6S A;  1NWL A;  2A3K A;  4RI5 A;  2F71 A;  3GXG A;  2PBN A;  3F99 A;  2CMC A;  1YZ4 A;  3AWG A;  4OHI A;  3H2X A;  2CNF A;  1ZC0 A;  1G1H A;  2HC2 A;  1YN9 A;  1M3G A;  4KYR A;  1GFY A;  2A8B A;  2B4P A;  2NT7 A;  1XRI A;  3ZV2 A;  1Q1M A;  4YAA A;  3QCF A;  2BGE A;  1PTY A;  2HB1 A;  1C83 A;  2FH7 A;  2HVL A;  1YGR A;  2CM2 A;  3I7Z A;  2PSZ A;  4S0G A;  1J4X A;  2GJT A;  1C87 A;  1C88 A;  3S3E A;  2QBS A;  3ZMP A;  3CM3 A;  3N0A A;  2CJZ A;  1JF7 A;  2VEV A;  4HJQ A;  2F6Z A;  4R0T A;  2I1Y A;  3BLT A;  3ZM0 A;  1T49 A;  2CNH A;  2PQ5 A;  2MBC A;  4GFV A;  1PA9 A;  1KAK A;  2F70 A;  3V0E A;  3D44 A;  3O3L A;  5KA4 A;  5KA7 A;  4R0S A;  2VEU A;  2QBQ A;  5BZZ A;  1RPM A;  4BJO A;  2NV5 A;  1OES A;  1ZCK A;  4QUM A;  2NT2 A;  3ZMQ A;  2G6Z A;  2QCJ A;  5K24 A;  4D3Q A;  4PYH A;  2C46 A;  4PVG A;  1L8G A;  4QBW A;  2G59 A;  3V0D A;  2OC3 A;  2QCT A;  2R0B A;  2Q47 A;  1PTV A;  3O4T A;  1NZ7 A;  2NZ6 A;  1X24 A;  3OLR A;  1PXH A;  2F6V A;  1BZH A;  1U25 A;  3EMU A;  2I4H A;  4R30 A;  3QCN A;  1D5R A;  4JMK A;  4NND A;  3QKQ A;  4ZI4 A;  3QCG A;  3I36 A;  1I9T A;  2I6M A;  1ECV A;  2P4D A;  5KA2 A;  4ERC A;  3D1Q A;  1EEO A;  5KAC A;  2H4G A;  1G7G A;  2PI7 A;  1OEV A;  2HNQ A;  2QDM A;  1V3A A;  1PTU A;  1XM2 A;  5K9V A;  1ZCL A;  1G4W R;  1JLN A;  2AZR A;  3D1O A;  1NL9 A;  4WU3 A;  3V0J A;  4B04 A;  4RHG A;  4ZRT A;  2QDP A;  4OHD A;  4HRF A;  2BV5 A;  4Y2E A;  1C84 A;  2FJM A;  3D42 A;  3V0I A;  1OEO X;  1XXP A;  5KAB A;  3QCH A;  4OHE A;  2P6X A;  3CWE A;  1I57 A;  4ICZ A;  5KA0 A;  2CNE A;  1QZ0 A;  1ZZW A;  2F6F A;  4OHH A;  3S4E A;  2CM3 A;  2H04 A;  3S4O A;  1PTT A;  4NYH A;  1L8K A;  2I6J A;  3I80 A;  1I9S A;  3PS5 A;  2JJD A;  1EEN A;  1C86 A;  1Q6T A;  3RO1 A;  2B4O A;  1ONY A;  1GWZ A;  1LAR A;  1R6H A;  4NWG A;  2I3U A;  4Y14 A;  3S3K A;  2H4V A;  1NNY A;  4ZN5 A;  1YTN A;  3OMH A;  2ZMM A;  3QCB A;  5IBM A;  3V0F A;  1FQ1 A;  1OET A;  4Z6B A;  5KA1 A;  4QAH A;  2Q05 A;  1YFO A;  2VEY A;  3LJ8 A;  4GS0 A;  2E0T A;  3AWF A;  1KAV A;  2I3R A;  2Y96 A;  4IKC A;  5IBS A;  5KAA A;  3MMJ A;  1XXV A;  5BUG A;  2I4G A;  1BZC A;  5HDE A;  3RGQ A;  2I6O A;  3QCL A;  1MKP A;  3QCK A; 
#chains in the Genus database with same CATH topology
 4I8N A;  3F81 A;  2F00 A;  3NME A;  1Q6N A;  3A5K A;  1FPR A;  1G1F A;  2I6I A;  4D3R A;  1C85 A;  1RXD A;  4GFU A;  4JNB A;  2RF6 A;  2BIJ A;  4UAG A;  5KA3 A;  2J16 A;  5KAD A;  2GC5 A;  2QBR A;  2I4E A;  2AM1 A;  2Y2F A;  5K25 A;  5EHR A;  2WGP A;  4OHL A;  1YGU A;  1OHD A;  2NTA A;  5K23 A;  4GE6 A;  1FPZ A;  2HY3 A;  4D3P A;  3S3F A;  1Q6P A;  1ONZ A;  2H4K A;  2JFG A;  2GC6 A;  4WTY A;  1U26 A;  2HC1 A;  1G4U S;  3EB1 A;  3F9A A;  1LYV A;  4GWF A;  4QDI A;  2B07 A;  1PYN A;  3QCJ A;  5AWX A;  2XJA A;  4NWF A;  4QAP A;  2Y67 A;  4KI9 A;  4BPC A;  5K9W A;  3RZ2 A;  2F6Y A;  1T4J A;  2OUD A;  5EHP A;  2FJN A;  2F6T A;  1T48 A;  4GE5 A;  3F41 A;  4JBC A;  2HNP A;  2YDU A;  2HXP A;  2GWO A;  2J16 B;  1WRM A;  4NX8 A;  3N2A A;  4DGP A;  2DXP A;  4MBB A;  3QCI A;  2X5O A;  2VOR A;  4BUC A;  3V0H A;  2OZ5 A;  3D9C A;  3AWE A;  5I6V A;  1OHC A;  1J6U A;  3O4S A;  4H1O A;  2B4U A;  1G1G A;  2CMB A;  1Q6M A;  3EZZ A;  4HV4 A;  5MMZ B;  3O4U A;  4YR8 B;  1YTS A;  1XBO A;  3UAG A;  2JFH A;  1OEM X;  2CM7 A;  5BZX A;  3SME A;  5KA8 A;  3MOZ A;  1NWE A;  2I5X A;  1P15 A;  2GP0 A;  4JMJ A;  3D1H A;  4WOH A;  1AAX A;  2WJP A;  1YWF A;  3NRS A;  4QUN A;  4QBE A;  1U24 A;  1PA1 A;  1EEH A;  5BX1 A;  5LXQ B;  4J51 A;  3MVN A;  2ZN7 A;  3BRH A;  4DGX A;  3ZL8 A;  2J17 A;  3ZM6 A;  3M4U A;  5GTJ A;  2M3V A;  1LQF A;  1WCH A;  2F46 A;  1P31 A;  2Y1O A;  5K22 A;  3ZM3 A;  2CNG A;  4GRZ A;  3B7O A;  2NLK A;  4RH5 A;  3QCM A;  2WTZ A;  2VOS A;  5M43 A;  1VHR A;  3RGO A;  3QCE A;  4H34 A;  4ZIY A;  4HJP A;  1YPT A;  2CM8 A;  3A5J A;  1WAX A;  2QBP A;  4GRY A;  2UUP A;  2B4S A;  4CVM A;  2C7S A;  1PH0 A;  2PA5 A;  1SUG A;  2VTE A;  3F9B A;  2CNI A;  2B49 A;  2QDC A;  2VEW A;  3O5X A;  3QCC A;  2VEX A;  5KA9 A;  2B3O A;  2IMG A;  4QF5 A;  1BZJ A;  2UUO A;  3ZM2 A;  2UAG A;  3EU0 A;  3MOW A;  2I75 A;  2CFV A;  1OHE A;  3SR9 A;  2BZL A;  2SHP A;  3GXH A;  3QKP A;  1OEU A;  1GQQ A;  2ESB A;  2H02 A;  4RKK A;  4AZ1 A;  1FGS A;  2HCM A;  2AHS A;  4RH9 A;  3QCD A;  3ZM1 A;  1NO6 A;  3ZM5 A;  4WU2 A;  4TVV A;  4RI4 A;  2PT0 A;  3BM8 A;  2CMA A;  5J8R A;  4BUB A;  3V0G A;  1P3D A;  3S3H A;  2I42 A;  1Q6J A;  1YTW A;  2OOQ A;  1E8C A;  4RDD A;  1A5Y A;  3EAX A;  4KYQ A;  3U96 A;  3BLU A;  2I6P A;  2QEP A;  4GE2 A;  2F6W A;  1G7F A;  1QXK A;  2H03 A;  2BGD A;  1Q6S A;  1NWL A;  2A3K A;  4RI5 A;  2F71 A;  3GXG A;  4CVL A;  2PBN A;  3F99 A;  2CMC A;  1YZ4 A;  3AWG A;  4OHI A;  3H2X A;  2CNF A;  3PYZ A;  1ZC0 A;  1G1H A;  2HC2 A;  1YN9 A;  5A5F A;  1M3G A;  4KYR A;  1GFY A;  2A8B A;  2B4P A;  2NT7 A;  1XRI A;  3ZV2 A;  1Q1M A;  4YAA A;  3QCF A;  2BGE A;  1PTY A;  2HB1 A;  1C83 A;  2FH7 A;  2HVL A;  1YGR A;  2CM2 A;  3I7Z A;  2PSZ A;  4S0G A;  1UAG A;  4CVK A;  1J4X A;  2GJT A;  1C87 A;  1C88 A;  4C12 A;  3S3E A;  2Y68 A;  2QBS A;  3ZMP A;  1JBW A;  1W7K A;  3CM3 A;  3N0A A;  2CJZ A;  1JF7 A;  2VEV A;  4HJQ A;  2F6Z A;  4R0T A;  2I1Y A;  3BLT A;  3ZM0 A;  1T49 A;  2CNH A;  2PQ5 A;  2MBC A;  4GFV A;  1PA9 A;  1KAK A;  2F70 A;  3V0E A;  3D44 A;  3O3L A;  5KA4 A;  5KA7 A;  4R0S A;  2VEU A;  2QBQ A;  5BZZ A;  1RPM A;  4BJO A;  2NV5 A;  1OES A;  1ZCK A;  4QUM A;  2NT2 A;  1O5Z A;  3ZMQ A;  2G6Z A;  2QCJ A;  5K24 A;  4D3Q A;  4PYH A;  2C46 A;  1GG4 A;  5A5E A;  4PVG A;  1L8G A;  4QBW A;  2G59 A;  3V0D A;  2OC3 A;  2QCT A;  2R0B A;  2Q47 A;  1PTV A;  3O4T A;  1NZ7 A;  2NZ6 A;  1X24 A;  3OLR A;  1PXH A;  2F6V A;  1BZH A;  1U25 A;  3EMU A;  2I4H A;  4R30 A;  3QCN A;  1D5R A;  4JMK A;  4NND A;  3QKQ A;  4ZI4 A;  2GCB A;  3QCG A;  3I36 A;  3QCZ A;  1I9T A;  2I6M A;  1ECV A;  2VTD A;  2P4D A;  5KA2 A;  4ERC A;  3D1Q A;  1E0D A;  1EEO A;  2JFF A;  5KAC A;  2H4G A;  1G7G A;  2PI7 A;  1OEV A;  2HNQ A;  2QDM A;  1V3A A;  1PTU A;  1XM2 A;  5K9V A;  1ZCL A;  1G4W R;  1JLN A;  2AZR A;  3D1O A;  1NL9 A;  4WU3 A;  3V0J A;  3HN7 A;  4B04 A;  4RHG A;  4ZRT A;  2GCA A;  2QDP A;  4OHD A;  4HRF A;  2BV5 A;  4Y2E A;  1C84 A;  2FJM A;  3D42 A;  3V0I A;  1OEO X;  1XXP A;  5KAB A;  3QCH A;  4OHE A;  2P6X A;  3CWE A;  1I57 A;  4ICZ A;  5KA0 A;  2CNE A;  1QZ0 A;  1ZZW A;  2F6F A;  4OHH A;  3S4E A;  2CM3 A;  2H04 A;  3S4O A;  1PTT A;  4NYH A;  1L8K A;  2I6J A;  3I80 A;  1I9S A;  2XPC A;  3PS5 A;  2JJD A;  1EEN A;  1C86 A;  1Q6T A;  3RO1 A;  2B4O A;  1ONY A;  1GWZ A;  1LAR A;  1W78 A;  1R6H A;  4NWG A;  4C13 A;  2I3U A;  4Y14 A;  3S3K A;  2H4V A;  1NNY A;  1GQY A;  4ZN5 A;  1YTN A;  3OMH A;  2ZMM A;  3QCB A;  5IBM A;  3V0F A;  1FQ1 A;  1OET A;  4Z6B A;  5KA1 A;  4QAH A;  2Q05 A;  1YFO A;  2VEY A;  3LJ8 A;  4GS0 A;  3LK7 A;  2E0T A;  3AWF A;  1KAV A;  2I3R A;  2Y96 A;  4IKC A;  5IBS A;  2AM2 A;  5KAA A;  3MMJ A;  1XXV A;  5BUG A;  1JBV A;  2I4G A;  1BZC A;  5HDE A;  3RGQ A;  2I6O A;  3QCL A;  1MKP A;  3QCK A;  2Y66 A; 
#chains in the Genus database with same CATH homology
 4I8N A;  3F81 A;  3NME A;  1Q6N A;  3A5K A;  1FPR A;  1G1F A;  2I6I A;  4D3R A;  1C85 A;  1RXD A;  4GFU A;  4JNB A;  2RF6 A;  2BIJ A;  5KA3 A;  2J16 A;  5KAD A;  2QBR A;  2I4E A;  2Y2F A;  5K25 A;  5EHR A;  2WGP A;  4OHL A;  1YGU A;  1OHD A;  2NTA A;  5K23 A;  4GE6 A;  1FPZ A;  2HY3 A;  4D3P A;  3S3F A;  1Q6P A;  1ONZ A;  2H4K A;  4WTY A;  1U26 A;  2HC1 A;  1G4U S;  3EB1 A;  3F9A A;  1LYV A;  4GWF A;  2B07 A;  1PYN A;  3QCJ A;  5AWX A;  4NWF A;  4QAP A;  4KI9 A;  4BPC A;  5K9W A;  3RZ2 A;  2F6Y A;  1T4J A;  2OUD A;  5EHP A;  2FJN A;  2F6T A;  1T48 A;  4GE5 A;  3F41 A;  4JBC A;  2HNP A;  2YDU A;  2HXP A;  2GWO A;  2J16 B;  1WRM A;  4NX8 A;  4DGP A;  2DXP A;  4MBB A;  3QCI A;  3V0H A;  2OZ5 A;  3D9C A;  3AWE A;  5I6V A;  1OHC A;  3O4S A;  4H1O A;  2B4U A;  1G1G A;  2CMB A;  1Q6M A;  3EZZ A;  5MMZ B;  3O4U A;  4YR8 B;  1YTS A;  1XBO A;  1OEM X;  2CM7 A;  5BZX A;  3SME A;  5KA8 A;  3MOZ A;  1NWE A;  2I5X A;  1P15 A;  2GP0 A;  4JMJ A;  3D1H A;  4WOH A;  1AAX A;  1YWF A;  4QUN A;  4QBE A;  1U24 A;  1PA1 A;  5BX1 A;  5LXQ B;  4J51 A;  2ZN7 A;  3BRH A;  4DGX A;  2J17 A;  3M4U A;  5GTJ A;  2M3V A;  1LQF A;  1WCH A;  2F46 A;  5K22 A;  3ZM3 A;  2CNG A;  4GRZ A;  3B7O A;  2NLK A;  4RH5 A;  3QCM A;  5M43 A;  1VHR A;  3RGO A;  3QCE A;  4H34 A;  4HJP A;  1YPT A;  2CM8 A;  3A5J A;  1WAX A;  2QBP A;  4GRY A;  2B4S A;  2C7S A;  1PH0 A;  2PA5 A;  1SUG A;  3F9B A;  2CNI A;  2B49 A;  2QDC A;  2VEW A;  3O5X A;  3QCC A;  2VEX A;  5KA9 A;  2B3O A;  2IMG A;  1BZJ A;  3ZM2 A;  3EU0 A;  3MOW A;  2I75 A;  2CFV A;  1OHE A;  3SR9 A;  2BZL A;  2SHP A;  3GXH A;  3QKP A;  1OEU A;  2ESB A;  2H02 A;  4RKK A;  4AZ1 A;  2HCM A;  2AHS A;  4RH9 A;  3QCD A;  3ZM1 A;  1NO6 A;  4WU2 A;  4TVV A;  4RI4 A;  2PT0 A;  3BM8 A;  2CMA A;  5J8R A;  3V0G A;  3S3H A;  2I42 A;  1Q6J A;  1YTW A;  2OOQ A;  4RDD A;  1A5Y A;  3EAX A;  4KYQ A;  3U96 A;  3BLU A;  2I6P A;  2QEP A;  4GE2 A;  2F6W A;  1G7F A;  1QXK A;  2H03 A;  2BGD A;  1Q6S A;  1NWL A;  2A3K A;  4RI5 A;  2F71 A;  3GXG A;  2PBN A;  3F99 A;  2CMC A;  1YZ4 A;  3AWG A;  4OHI A;  3H2X A;  2CNF A;  1ZC0 A;  1G1H A;  2HC2 A;  1YN9 A;  1M3G A;  4KYR A;  1GFY A;  2A8B A;  2B4P A;  2NT7 A;  1XRI A;  3ZV2 A;  1Q1M A;  4YAA A;  3QCF A;  2BGE A;  1PTY A;  2HB1 A;  1C83 A;  2FH7 A;  2HVL A;  1YGR A;  2CM2 A;  3I7Z A;  2PSZ A;  4S0G A;  1J4X A;  2GJT A;  1C87 A;  1C88 A;  3S3E A;  2QBS A;  3ZMP A;  3CM3 A;  3N0A A;  2CJZ A;  1JF7 A;  2VEV A;  4HJQ A;  2F6Z A;  4R0T A;  2I1Y A;  3BLT A;  3ZM0 A;  1T49 A;  2CNH A;  2PQ5 A;  2MBC A;  4GFV A;  1PA9 A;  1KAK A;  2F70 A;  3V0E A;  3D44 A;  3O3L A;  5KA4 A;  5KA7 A;  4R0S A;  2VEU A;  2QBQ A;  5BZZ A;  1RPM A;  4BJO A;  2NV5 A;  1OES A;  1ZCK A;  4QUM A;  2NT2 A;  3ZMQ A;  2G6Z A;  2QCJ A;  5K24 A;  4D3Q A;  4PYH A;  2C46 A;  4PVG A;  1L8G A;  4QBW A;  2G59 A;  3V0D A;  2OC3 A;  2QCT A;  2R0B A;  2Q47 A;  1PTV A;  3O4T A;  1NZ7 A;  2NZ6 A;  1X24 A;  3OLR A;  1PXH A;  2F6V A;  1BZH A;  1U25 A;  3EMU A;  2I4H A;  4R30 A;  3QCN A;  1D5R A;  4JMK A;  4NND A;  3QKQ A;  4ZI4 A;  3QCG A;  3I36 A;  1I9T A;  2I6M A;  1ECV A;  2P4D A;  5KA2 A;  4ERC A;  3D1Q A;  1EEO A;  5KAC A;  2H4G A;  1G7G A;  2PI7 A;  1OEV A;  2HNQ A;  2QDM A;  1V3A A;  1PTU A;  1XM2 A;  5K9V A;  1ZCL A;  1G4W R;  1JLN A;  2AZR A;  3D1O A;  1NL9 A;  4WU3 A;  3V0J A;  4B04 A;  4RHG A;  4ZRT A;  2QDP A;  4OHD A;  4HRF A;  2BV5 A;  4Y2E A;  1C84 A;  2FJM A;  3D42 A;  3V0I A;  1OEO X;  1XXP A;  5KAB A;  3QCH A;  4OHE A;  2P6X A;  3CWE A;  1I57 A;  4ICZ A;  5KA0 A;  2CNE A;  1QZ0 A;  1ZZW A;  2F6F A;  4OHH A;  3S4E A;  2CM3 A;  2H04 A;  3S4O A;  1PTT A;  4NYH A;  1L8K A;  2I6J A;  3I80 A;  1I9S A;  3PS5 A;  2JJD A;  1EEN A;  1C86 A;  1Q6T A;  3RO1 A;  2B4O A;  1ONY A;  1GWZ A;  1LAR A;  1R6H A;  4NWG A;  2I3U A;  4Y14 A;  3S3K A;  2H4V A;  1NNY A;  4ZN5 A;  1YTN A;  3OMH A;  2ZMM A;  3QCB A;  5IBM A;  3V0F A;  1FQ1 A;  1OET A;  4Z6B A;  5KA1 A;  4QAH A;  2Q05 A;  1YFO A;  2VEY A;  3LJ8 A;  4GS0 A;  2E0T A;  3AWF A;  1KAV A;  2I3R A;  2Y96 A;  4IKC A;  5IBS A;  5KAA A;  3MMJ A;  1XXV A;  5BUG A;  2I4G A;  1BZC A;  5HDE A;  3RGQ A;  2I6O A;  3QCL A;  1MKP A;  3QCK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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