3BRHA

Protein tyrosine phosphatase ptpn-22 (lyp) bound to the mono-phosphorylated lck active site peptide
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
296
structure length
296
Chain Sequence
QREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPAHDVPSSIDPILELIWDVRCYQEDDSVPICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 97
structure length 296
sequence length 296
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3brhA00
3D42A 1Q6MA 2I3UA 2C46A 1LQFA 1ZC0A 5GTJA 4NX8A 1PTUA 2GWOA 1GFYA 1G1FA 3F41A 1EENA 4OHHA 2Y96A 1LYVA 2PI7A 3CWEA 4QAHA 1L8GA 3QCFA 1Q6JA 5EHRA 1I9SA 1OEMX 1PH0A 3D1QA 4NNDA 5KAAA 2OC3A 4OHLA 3S3FA 1T48A 2QBQA 2F6ZA 4DGPA 5KA4A 4Y2EA 1T4JA 1G4WR 4NWGA 2HNQA 1C87A 1Q1MA 3F81A 2I6OA 2MBCA 4RDDA 4R30A 3NMEA 1NNYA 3D44A 2F46A 2HC2A 2F6YA 3RZ2A 2OUDA 1PTTA 1YTWA 3AWGA 1A5YA 1ONZA 2H04A 3V0JA 1BZCA 4NYHA 1FQ1A 4PYHA 3QCNA 2CM8A 4OHIA 3AWEA 1RPMA 1XXVA 2CNGA 2QBPA 1P15A 5BZZA 2NZ6A 3SMEA 3ZM1A 2GJTA 2ESBA 1OEUA 1FPRA 1C84A 3I36A 2I42A 4JMKA 3OLRA 4QUNA 3EAXA 3H2XA 1YFOA 4GE6A 3V0IA 1NL9A 1WAXA 4H1OA 2HC1A 3F9BA 4RH5A 2F6FA 2QDMA 2HNPA 1M3GA 1YZ4A 2J16A 3O4TA 1BZHA 2M3VA 2C7SA 2PQ5A 1NWEA 1J4XA 1KAKA 3V0DA 1G7GA 2HXPA 2F71A 4NWFA 4BJOA 3MOWA 1C86A 1YTSA 1G1GA 1JF7A 1LARA 2CM3A 1Q6SA 3QCKA 3ZM2A 3QKQA 1OEOX 1U24A 2B07A 2QCJA 2HY3A 3S4EA 2NTAA 3F9AA 1R6HA 5KA0A 3QCCA 5KA8A 1OETA 1QXKA 2NLKA 2CNFA 4OHDA 2B4UA 4HJPA 4ZI4A 3QCDA 3O4UA 4TVVA 1Q6PA 4R0SA 3I80A 1XBOA 1G7FA 4KYQA 2I4GA 4QBWA 3EB1A 1NO6A 2DXPA 2F6VA 5IBSA 3EZZA 1WCHA 2PT0A 2J16B 1PTYA 2I6IA 4JMJA 5KADA 5EHPA 3ZV2A 4WU3A 4R0TA 3B7OA 3PS5A 4JNBA 3S3EA 4GRZA 2CNIA 2CFVA 2VEUA 1OHEA 2FJNA 2AHSA 3QCIA 3F99A 2VEXA 1NZ7A 2H4KA 2ZN7A 3QCGA 1YGRA 2J17A 3EMUA 1G1HA 1XRIA 2A8BA 1AAXA 4WU2A 4QUMA 3QCEA 2B4OA 2I4EA 4B04A 2I4HA 2CNHA 1PTVA 3QCHA 5IBMA 3MMJA 2BV5A 2F6TA 3D1HA 1GWZA 4BPCA 4D3QA 2CM7A 4D3PA 5K23A 5KA3A 3D9CA 1U26A 1PYNA 3V0EA 3QCBA 1ONYA 3ZMPA 1YPTA 1JLNA 2I6PA 3N0AA 4ERCA 1PXHA 4GE2A 3D1OA 2G59A 3BLUA 2RF6A 2R0BA 2QDPA 4HJQA 5HDEA 2CJZA 4Z6BA 1X24A 3S4OA 3OMHA 1XXPA 5AWXA 2HVLA 2B3OA 1C83A 5K9WA 1KAVA 2FJMA 1ZCLA 3O4SA 1EEOA 1Q6TA 2VEWA 3GXGA 3S3KA 2I75A 4GS0A 2I3RA 5KA9A 2NV5A 1VHRA 3V0HA 4ZN5A 5KABA 2P4DA 4YAAA 2NT2A 2B4PA 3M4UA 1OHCA 1G4US 1PA9A 4PVGA 2QBRA 4QBEA 4J51A 1YGUA 4D3RA 3BLTA 2I6MA 1FPZA 2Q47A 4QAPA 3AWFA 2BGDA 4H34A 3LJ8A 4IKCA 4AZ1A 3ZM3A 1I57A 5KA1A 2CNEA 4ZRTA 4MBBA 2F6WA 2QDCA 2BZLA 2I1YA 5I6VA 5K24A 2G6ZA 4RI5A 1C88A 2YDUA 2P6XA 3MOZA 3O3LA 5BX1A 2Q05A 2E0TA 2B49A 2H03A 3V0FA 3QKPA 2OZ5A 2H4GA 4YR8B 2CMAA 2AZRA 4WOHA 2BGEA 2QEPA 5KA7A 1C85A 1ZCKA 4Y14A 1PA1A 2NT7A 4RI4A 2H4VA 3ZMQA 4DGXA 5KACA 2IMGA 3RO1A 4S0GA 3QCLA 4OHEA 1NWLA 5BUGA 2CMCA 2QCTA 3ZM0A 1QZ0A 1WRMA 1U25A 2HCMA 3QCMA 4GFUA 2WGPA 1RXDA 1YTNA 2QBSA 2B4SA 4KI9A 4WTYA 5K9VA 2I6JA 3O5XA 3QCJA 4RKKA 2PBNA 2VEVA 4ICZA 1V3AA 1OHDA 5MMZB 2PSZA 5K25A 2PA5A 3BM8A 1BZJA 1T49A 3V0GA 3GXHA 4HRFA 5K22A 2I5XA 3EU0A 2H02A 1OEVA 2HB1A 1OESA 2CMBA 4GWFA 3RGQA 3BRHA 1YN9A 1Q6NA 5J8RA 1ZZWA 3U96A 1MKPA 2SHPA 4GRYA 4KYRA 1YWFA 3A5KA 1D5RA 4RH9A 5BZXA 1I9TA 2OOQA 2F70A 2BIJA 3I7ZA 3S3HA 5KA2A 2ZMMA 4JBCA 4GFVA 2Y2FA 2JJDA 3A5JA 5M43A 2FH7A 1SUGA 5LXQB 3RGOA 2CM2A 2A3KA 3CM3A 4I8NA 1L8KA 2VEYA 1XM2A 3SR9A 1ECVA 2GP0A 4GE5A 4RHGA
chains in the Genus database with same CATH superfamily
3D42A 1Q6MA 2I3UA 2C46A 1LQFA 2VORA 1ZC0A 5GTJA 4NX8A 1PTUA 3N2AA 2GWOA 1GFYA 1G1FA 3F41A 1EENA 4OHHA 4CVMA 2Y96A 1LYVA 2PI7A 3HN7A 3CWEA 4QAHA 1L8GA 3QCFA 1Q6JA 5EHRA 1I9SA 1OEMX 1PH0A 3D1QA 4NNDA 5KAAA 2OC3A 4OHLA 3S3FA 1W78A 1T48A 2QBQA 2F6ZA 4DGPA 5KA4A 4Y2EA 1T4JA 1G4WR 4NWGA 2HNQA 1C87A 1Q1MA 3F81A 2I6OA 2MBCA 4RDDA 2JFGA 4R30A 3NMEA 1NNYA 3D44A 2F46A 2HC2A 2F6YA 2AM1A 4ZIYA 3NRSA 3RZ2A 2OUDA 1PTTA 1YTWA 3AWGA 1A5YA 1ONZA 2H04A 3V0JA 1BZCA 2JFFA 4NYHA 1FQ1A 4PYHA 3QCNA 2CM8A 4OHIA 3AWEA 4C13A 1RPMA 1XXVA 2CNGA 2QBPA 1P15A 5BZZA 2NZ6A 3SMEA 3ZM1A 2GJTA 2ESBA 1OEUA 1FPRA 1C84A 3I36A 2I42A 4JMKA 3OLRA 4QUNA 3EAXA 3H2XA 1YFOA 4GE6A 3V0IA 1NL9A 1WAXA 4H1OA 2GCAA 2HC1A 3F9BA 4RH5A 2F6FA 2QDMA 2HNPA 1M3GA 1YZ4A 4HV4A 2J16A 3O4TA 1BZHA 2M3VA 2C7SA 2PQ5A 2UUOA 1NWEA 1J4XA 1KAKA 3V0DA 1G7GA 2HXPA 2F71A 2UAGA 4NWFA 4BJOA 3MOWA 1C86A 1P3DA 1YTSA 1G1GA 1JF7A 1LARA 2CM3A 1Q6SA 3QCKA 3ZM2A 3QKQA 1OEOX 1U24A 2B07A 2QCJA 1JBVA 3ZM5A 2HY3A 3S4EA 2NTAA 3F9AA 1R6HA 4UAGA 3UAGA 5KA0A 3QCCA 5KA8A 3LK7A 1OETA 1QXKA 2NLKA 2CNFA 1E0DA 4OHDA 2B4UA 4HJPA 4ZI4A 3QCDA 3O4UA 4TVVA 1Q6PA 4R0SA 3I80A 1XBOA 1G7FA 4KYQA 2I4GA 4QBWA 3EB1A 1NO6A 2DXPA 2F6VA 5IBSA 3EZZA 1WCHA 2PT0A 2J16B 1PTYA 2I6IA 4JMJA 5KADA 5EHPA 3ZV2A 4WU3A 4R0TA 3B7OA 2UUPA 1GQQA 3PS5A 4JNBA 3S3EA 4GRZA 2CNIA 2CFVA 2VEUA 1OHEA 2FJNA 2AHSA 3QCIA 3F99A 2VEXA 1NZ7A 2H4KA 2ZN7A 3QCGA 1YGRA 2J17A 3EMUA 1G1HA 1XRIA 2A8BA 1AAXA 4WU2A 4QUMA 3QCEA 2GC6A 2B4OA 2I4EA 4B04A 2I4HA 2CNHA 2GC5A 1PTVA 3QCHA 5IBMA 3MMJA 2BV5A 2F6TA 3D1HA 1GWZA 4BPCA 4D3QA 5A5EA 5A5FA 2CM7A 1J6UA 4D3PA 5K23A 2GCBA 5KA3A 3D9CA 1U26A 1PYNA 3V0EA 3QCBA 1ONYA 3ZMPA 1YPTA 1JLNA 2I6PA 3N0AA 2Y67A 4ERCA 1E8CA 1PXHA 4GE2A 4QDIA 4BUCA 4BUBA 3D1OA 2G59A 3BLUA 2RF6A 2R0BA 2QDPA 4HJQA 5HDEA 2CJZA 4Z6BA 1X24A 3S4OA 2VTEA 3OMHA 1XXPA 5AWXA 2HVLA 2B3OA 1GG4A 1C83A 5K9WA 1KAVA 2FJMA 1ZCLA 3O4SA 1EEOA 1Q6TA 2VEWA 3GXGA 3S3KA 2I75A 4GS0A 2I3RA 5KA9A 2NV5A 1VHRA 3V0HA 4ZN5A 5KABA 2P4DA 4YAAA 2NT2A 1FGSA 2B4PA 3M4UA 1OHCA 1G4US 1O5ZA 1PA9A 4PVGA 2QBRA 4QBEA 4J51A 1YGUA 4D3RA 3BLTA 2Y1OA 2AM2A 2I6MA 1FPZA 2Q47A 4QAPA 2XJAA 3AWFA 2BGDA 4H34A 3LJ8A 4IKCA 4AZ1A 4C12A 3QCZA 3ZM3A 2F00A 1I57A 5KA1A 2CNEA 2WTZA 4ZRTA 2X5OA 4MBBA 2F6WA 2QDCA 2BZLA 2I1YA 5I6VA 5K24A 4CVKA 2G6ZA 4RI5A 1C88A 2YDUA 2P6XA 2VTDA 1JBWA 3MOZA 3O3LA 5BX1A 2Q05A 2E0TA 2B49A 2H03A 3V0FA 3QKPA 2OZ5A 2H4GA 4YR8B 2CMAA 2AZRA 4WOHA 2BGEA 2QEPA 5KA7A 1C85A 1ZCKA 4Y14A 1PA1A 2NT7A 4RI4A 2H4VA 3ZMQA 4DGXA 5KACA 2IMGA 3RO1A 4S0GA 3QCLA 4OHEA 1NWLA 5BUGA 2CMCA 2QCTA 3ZM0A 1QZ0A 2JFHA 1WRMA 1U25A 2HCMA 3QCMA 4GFUA 4CVLA 2WGPA 1RXDA 1YTNA 2QBSA 2B4SA 4KI9A 4WTYA 5K9VA 2I6JA 3O5XA 3QCJA 4RKKA 2PBNA 1GQYA 2VEVA 2VOSA 4ICZA 1V3AA 2XPCA 1OHDA 5MMZB 1P31A 2PSZA 3MVNA 2WJPA 5K25A 2PA5A 2Y66A 3BM8A 1BZJA 1T49A 3V0GA 3GXHA 1W7KA 4HRFA 5K22A 2I5XA 3EU0A 2H02A 1OEVA 2HB1A 1OESA 2CMBA 4GWFA 3RGQA 3BRHA 1YN9A 1Q6NA 5J8RA 1ZZWA 3U96A 1MKPA 2SHPA 1UAGA 4GRYA 1EEHA 4KYRA 3ZM6A 4QF5A 2Y68A 1YWFA 3A5KA 1D5RA 4RH9A 5BZXA 1I9TA 2OOQA 2F70A 2BIJA 3I7ZA 3S3HA 5KA2A 2ZMMA 4JBCA 4GFVA 3PYZA 2Y2FA 2JJDA 3A5JA 5M43A 2FH7A 1SUGA 3ZL8A 5LXQB 3RGOA 2CM2A 2A3KA 3CM3A 4I8NA 1L8KA 2VEYA 1XM2A 3SR9A 1ECVA 2GP0A 4GE5A 4RHGA
chains in the Genus database with same CATH topology
3D42A 1Q6MA 2I3UA 2C46A 1LQFA 1ZC0A 5GTJA 4NX8A 1PTUA 2GWOA 1GFYA 1G1FA 3F41A 1EENA 4OHHA 2Y96A 1LYVA 2PI7A 3CWEA 4QAHA 1L8GA 3QCFA 1Q6JA 5EHRA 1I9SA 1OEMX 1PH0A 3D1QA 4NNDA 5KAAA 2OC3A 4OHLA 3S3FA 1T48A 2QBQA 2F6ZA 4DGPA 5KA4A 4Y2EA 1T4JA 1G4WR 4NWGA 2HNQA 1C87A 1Q1MA 3F81A 2I6OA 2MBCA 4RDDA 4R30A 3NMEA 1NNYA 3D44A 2F46A 2HC2A 2F6YA 3RZ2A 2OUDA 1PTTA 1YTWA 3AWGA 1A5YA 1ONZA 2H04A 3V0JA 1BZCA 4NYHA 1FQ1A 4PYHA 3QCNA 2CM8A 4OHIA 3AWEA 1RPMA 1XXVA 2CNGA 2QBPA 1P15A 5BZZA 2NZ6A 3SMEA 3ZM1A 2GJTA 2ESBA 1OEUA 1FPRA 1C84A 3I36A 2I42A 4JMKA 3OLRA 4QUNA 3EAXA 3H2XA 1YFOA 4GE6A 3V0IA 1NL9A 1WAXA 4H1OA 2HC1A 3F9BA 4RH5A 2F6FA 2QDMA 2HNPA 1M3GA 1YZ4A 2J16A 3O4TA 1BZHA 2M3VA 2C7SA 2PQ5A 1NWEA 1J4XA 1KAKA 3V0DA 1G7GA 2HXPA 2F71A 4NWFA 4BJOA 3MOWA 1C86A 1YTSA 1G1GA 1JF7A 1LARA 2CM3A 1Q6SA 3QCKA 3ZM2A 3QKQA 1OEOX 1U24A 2B07A 2QCJA 2HY3A 3S4EA 2NTAA 3F9AA 1R6HA 5KA0A 3QCCA 5KA8A 1OETA 1QXKA 2NLKA 2CNFA 4OHDA 2B4UA 4HJPA 4ZI4A 3QCDA 3O4UA 4TVVA 1Q6PA 4R0SA 3I80A 1XBOA 1G7FA 4KYQA 2I4GA 4QBWA 3EB1A 1NO6A 2DXPA 2F6VA 5IBSA 3EZZA 1WCHA 2PT0A 2J16B 1PTYA 2I6IA 4JMJA 5KADA 5EHPA 3ZV2A 4WU3A 4R0TA 3B7OA 3PS5A 4JNBA 3S3EA 4GRZA 2CNIA 2CFVA 2VEUA 1OHEA 2FJNA 2AHSA 3QCIA 3F99A 2VEXA 1NZ7A 2H4KA 2ZN7A 3QCGA 1YGRA 2J17A 3EMUA 1G1HA 1XRIA 2A8BA 1AAXA 4WU2A 4QUMA 3QCEA 2B4OA 2I4EA 4B04A 2I4HA 2CNHA 1PTVA 3QCHA 5IBMA 3MMJA 2BV5A 2F6TA 3D1HA 1GWZA 4BPCA 4D3QA 2CM7A 4D3PA 5K23A 5KA3A 3D9CA 1U26A 1PYNA 3V0EA 3QCBA 1ONYA 3ZMPA 1YPTA 1JLNA 2I6PA 3N0AA 4ERCA 1PXHA 4GE2A 3D1OA 2G59A 3BLUA 2RF6A 2R0BA 2QDPA 4HJQA 5HDEA 2CJZA 4Z6BA 1X24A 3S4OA 3OMHA 1XXPA 5AWXA 2HVLA 2B3OA 1C83A 5K9WA 1KAVA 2FJMA 1ZCLA 3O4SA 1EEOA 1Q6TA 2VEWA 3GXGA 3S3KA 2I75A 4GS0A 2I3RA 5KA9A 2NV5A 1VHRA 3V0HA 4ZN5A 5KABA 2P4DA 4YAAA 2NT2A 2B4PA 3M4UA 1OHCA 1G4US 1PA9A 4PVGA 2QBRA 4QBEA 4J51A 1YGUA 4D3RA 3BLTA 2I6MA 1FPZA 2Q47A 4QAPA 3AWFA 2BGDA 4H34A 3LJ8A 4IKCA 4AZ1A 3ZM3A 1I57A 5KA1A 2CNEA 4ZRTA 4MBBA 2F6WA 2QDCA 2BZLA 2I1YA 5I6VA 5K24A 2G6ZA 4RI5A 1C88A 2YDUA 2P6XA 3MOZA 3O3LA 5BX1A 2Q05A 2E0TA 2B49A 2H03A 3V0FA 3QKPA 2OZ5A 2H4GA 4YR8B 2CMAA 2AZRA 4WOHA 2BGEA 2QEPA 5KA7A 1C85A 1ZCKA 4Y14A 1PA1A 2NT7A 4RI4A 2H4VA 3ZMQA 4DGXA 5KACA 2IMGA 3RO1A 4S0GA 3QCLA 4OHEA 1NWLA 5BUGA 2CMCA 2QCTA 3ZM0A 1QZ0A 1WRMA 1U25A 2HCMA 3QCMA 4GFUA 2WGPA 1RXDA 1YTNA 2QBSA 2B4SA 4KI9A 4WTYA 5K9VA 2I6JA 3O5XA 3QCJA 4RKKA 2PBNA 2VEVA 4ICZA 1V3AA 1OHDA 5MMZB 2PSZA 5K25A 2PA5A 3BM8A 1BZJA 1T49A 3V0GA 3GXHA 4HRFA 5K22A 2I5XA 3EU0A 2H02A 1OEVA 2HB1A 1OESA 2CMBA 4GWFA 3RGQA 3BRHA 1YN9A 1Q6NA 5J8RA 1ZZWA 3U96A 1MKPA 2SHPA 4GRYA 4KYRA 1YWFA 3A5KA 1D5RA 4RH9A 5BZXA 1I9TA 2OOQA 2F70A 2BIJA 3I7ZA 3S3HA 5KA2A 2ZMMA 4JBCA 4GFVA 2Y2FA 2JJDA 3A5JA 5M43A 2FH7A 1SUGA 5LXQB 3RGOA 2CM2A 2A3KA 3CM3A 4I8NA 1L8KA 2VEYA 1XM2A 3SR9A 1ECVA 2GP0A 4GE5A 4RHGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D42 A;  1Q6M A;  2I3U A;  2C46 A;  1LQF A;  1ZC0 A;  5GTJ A;  4NX8 A;  1PTU A;  2GWO A;  1GFY A;  1G1F A;  3F41 A;  1EEN A;  4OHH A;  2Y96 A;  1LYV A;  2PI7 A;  3CWE A;  4QAH A;  1L8G A;  3QCF A;  1Q6J A;  5EHR A;  1I9S A;  1OEM X;  1PH0 A;  3D1Q A;  4NND A;  5KAA A;  2OC3 A;  4OHL A;  3S3F A;  1T48 A;  2QBQ A;  2F6Z A;  4DGP A;  5KA4 A;  4Y2E A;  1T4J A;  1G4W R;  4NWG A;  2HNQ A;  1C87 A;  1Q1M A;  3F81 A;  2I6O A;  2MBC A;  4RDD A;  4R30 A;  3NME A;  1NNY A;  3D44 A;  2F46 A;  2HC2 A;  2F6Y A;  3RZ2 A;  2OUD A;  1PTT A;  1YTW A;  3AWG A;  1A5Y A;  1ONZ A;  2H04 A;  3V0J A;  1BZC A;  4NYH A;  1FQ1 A;  4PYH A;  3QCN A;  2CM8 A;  4OHI A;  3AWE A;  1RPM A;  1XXV A;  2CNG A;  2QBP A;  1P15 A;  5BZZ A;  2NZ6 A;  3SME A;  3ZM1 A;  2GJT A;  2ESB A;  1OEU A;  1FPR A;  1C84 A;  3I36 A;  2I42 A;  4JMK A;  3OLR A;  4QUN A;  3EAX A;  3H2X A;  1YFO A;  4GE6 A;  3V0I A;  1NL9 A;  1WAX A;  4H1O A;  2HC1 A;  3F9B A;  4RH5 A;  2F6F A;  2QDM A;  2HNP A;  1M3G A;  1YZ4 A;  2J16 A;  3O4T A;  1BZH A;  2M3V A;  2C7S A;  2PQ5 A;  1NWE A;  1J4X A;  1KAK A;  3V0D A;  1G7G A;  2HXP A;  2F71 A;  4NWF A;  4BJO A;  3MOW A;  1C86 A;  1YTS A;  1G1G A;  1JF7 A;  1LAR A;  2CM3 A;  1Q6S A;  3QCK A;  3ZM2 A;  3QKQ A;  1OEO X;  1U24 A;  2B07 A;  2QCJ A;  2HY3 A;  3S4E A;  2NTA A;  3F9A A;  1R6H A;  5KA0 A;  3QCC A;  5KA8 A;  1OET A;  1QXK A;  2NLK A;  2CNF A;  4OHD A;  2B4U A;  4HJP A;  4ZI4 A;  3QCD A;  3O4U A;  4TVV A;  1Q6P A;  4R0S A;  3I80 A;  1XBO A;  1G7F A;  4KYQ A;  2I4G A;  4QBW A;  3EB1 A;  1NO6 A;  2DXP A;  2F6V A;  5IBS A;  3EZZ A;  1WCH A;  2PT0 A;  2J16 B;  1PTY A;  2I6I A;  4JMJ A;  5KAD A;  5EHP A;  3ZV2 A;  4WU3 A;  4R0T A;  3B7O A;  3PS5 A;  4JNB A;  3S3E A;  4GRZ A;  2CNI A;  2CFV A;  2VEU A;  1OHE A;  2FJN A;  2AHS A;  3QCI A;  3F99 A;  2VEX A;  1NZ7 A;  2H4K A;  2ZN7 A;  3QCG A;  1YGR A;  2J17 A;  3EMU A;  1G1H A;  1XRI A;  2A8B A;  1AAX A;  4WU2 A;  4QUM A;  3QCE A;  2B4O A;  2I4E A;  4B04 A;  2I4H A;  2CNH A;  1PTV A;  3QCH A;  5IBM A;  3MMJ A;  2BV5 A;  2F6T A;  3D1H A;  1GWZ A;  4BPC A;  4D3Q A;  2CM7 A;  4D3P A;  5K23 A;  5KA3 A;  3D9C A;  1U26 A;  1PYN A;  3V0E A;  3QCB A;  1ONY A;  3ZMP A;  1YPT A;  1JLN A;  2I6P A;  3N0A A;  4ERC A;  1PXH A;  4GE2 A;  3D1O A;  2G59 A;  3BLU A;  2RF6 A;  2R0B A;  2QDP A;  4HJQ A;  5HDE A;  2CJZ A;  4Z6B A;  1X24 A;  3S4O A;  3OMH A;  1XXP A;  5AWX A;  2HVL A;  2B3O A;  1C83 A;  5K9W A;  1KAV A;  2FJM A;  1ZCL A;  3O4S A;  1EEO A;  1Q6T A;  2VEW A;  3GXG A;  3S3K A;  2I75 A;  4GS0 A;  2I3R A;  5KA9 A;  2NV5 A;  1VHR A;  3V0H A;  4ZN5 A;  5KAB A;  2P4D A;  4YAA A;  2NT2 A;  2B4P A;  3M4U A;  1OHC A;  1G4U S;  1PA9 A;  4PVG A;  2QBR A;  4QBE A;  4J51 A;  1YGU A;  4D3R A;  3BLT A;  2I6M A;  1FPZ A;  2Q47 A;  4QAP A;  3AWF A;  2BGD A;  4H34 A;  3LJ8 A;  4IKC A;  4AZ1 A;  3ZM3 A;  1I57 A;  5KA1 A;  2CNE A;  4ZRT A;  4MBB A;  2F6W A;  2QDC A;  2BZL A;  2I1Y A;  5I6V A;  5K24 A;  2G6Z A;  4RI5 A;  1C88 A;  2YDU A;  2P6X A;  3MOZ A;  3O3L A;  5BX1 A;  2Q05 A;  2E0T A;  2B49 A;  2H03 A;  3V0F A;  3QKP A;  2OZ5 A;  2H4G A;  4YR8 B;  2CMA A;  2AZR A;  4WOH A;  2BGE A;  2QEP A;  5KA7 A;  1C85 A;  1ZCK A;  4Y14 A;  1PA1 A;  2NT7 A;  4RI4 A;  2H4V A;  3ZMQ A;  4DGX A;  5KAC A;  2IMG A;  3RO1 A;  4S0G A;  3QCL A;  4OHE A;  1NWL A;  5BUG A;  2CMC A;  2QCT A;  3ZM0 A;  1QZ0 A;  1WRM A;  1U25 A;  2HCM A;  3QCM A;  4GFU A;  2WGP A;  1RXD A;  1YTN A;  2QBS A;  2B4S A;  4KI9 A;  4WTY A;  5K9V A;  2I6J A;  3O5X A;  3QCJ A;  4RKK A;  2PBN A;  2VEV A;  4ICZ A;  1V3A A;  1OHD A;  5MMZ B;  2PSZ A;  5K25 A;  2PA5 A;  3BM8 A;  1BZJ A;  1T49 A;  3V0G A;  3GXH A;  4HRF A;  5K22 A;  2I5X A;  3EU0 A;  2H02 A;  1OEV A;  2HB1 A;  1OES A;  2CMB A;  4GWF A;  3RGQ A;  3BRH A;  1YN9 A;  1Q6N A;  5J8R A;  1ZZW A;  3U96 A;  1MKP A;  2SHP A;  4GRY A;  4KYR A;  1YWF A;  3A5K A;  1D5R A;  4RH9 A;  5BZX A;  1I9T A;  2OOQ A;  2F70 A;  2BIJ A;  3I7Z A;  3S3H A;  5KA2 A;  2ZMM A;  4JBC A;  4GFV A;  2Y2F A;  2JJD A;  3A5J A;  5M43 A;  2FH7 A;  1SUG A;  5LXQ B;  3RGO A;  2CM2 A;  2A3K A;  3CM3 A;  4I8N A;  1L8K A;  2VEY A;  1XM2 A;  3SR9 A;  1ECV A;  2GP0 A;  4GE5 A;  4RHG A; 
#chains in the Genus database with same CATH topology
 3D42 A;  1Q6M A;  2I3U A;  2C46 A;  1LQF A;  2VOR A;  1ZC0 A;  5GTJ A;  4NX8 A;  1PTU A;  3N2A A;  2GWO A;  1GFY A;  1G1F A;  3F41 A;  1EEN A;  4OHH A;  4CVM A;  2Y96 A;  1LYV A;  2PI7 A;  3HN7 A;  3CWE A;  4QAH A;  1L8G A;  3QCF A;  1Q6J A;  5EHR A;  1I9S A;  1OEM X;  1PH0 A;  3D1Q A;  4NND A;  5KAA A;  2OC3 A;  4OHL A;  3S3F A;  1W78 A;  1T48 A;  2QBQ A;  2F6Z A;  4DGP A;  5KA4 A;  4Y2E A;  1T4J A;  1G4W R;  4NWG A;  2HNQ A;  1C87 A;  1Q1M A;  3F81 A;  2I6O A;  2MBC A;  4RDD A;  2JFG A;  4R30 A;  3NME A;  1NNY A;  3D44 A;  2F46 A;  2HC2 A;  2F6Y A;  2AM1 A;  4ZIY A;  3NRS A;  3RZ2 A;  2OUD A;  1PTT A;  1YTW A;  3AWG A;  1A5Y A;  1ONZ A;  2H04 A;  3V0J A;  1BZC A;  2JFF A;  4NYH A;  1FQ1 A;  4PYH A;  3QCN A;  2CM8 A;  4OHI A;  3AWE A;  4C13 A;  1RPM A;  1XXV A;  2CNG A;  2QBP A;  1P15 A;  5BZZ A;  2NZ6 A;  3SME A;  3ZM1 A;  2GJT A;  2ESB A;  1OEU A;  1FPR A;  1C84 A;  3I36 A;  2I42 A;  4JMK A;  3OLR A;  4QUN A;  3EAX A;  3H2X A;  1YFO A;  4GE6 A;  3V0I A;  1NL9 A;  1WAX A;  4H1O A;  2GCA A;  2HC1 A;  3F9B A;  4RH5 A;  2F6F A;  2QDM A;  2HNP A;  1M3G A;  1YZ4 A;  4HV4 A;  2J16 A;  3O4T A;  1BZH A;  2M3V A;  2C7S A;  2PQ5 A;  2UUO A;  1NWE A;  1J4X A;  1KAK A;  3V0D A;  1G7G A;  2HXP A;  2F71 A;  2UAG A;  4NWF A;  4BJO A;  3MOW A;  1C86 A;  1P3D A;  1YTS A;  1G1G A;  1JF7 A;  1LAR A;  2CM3 A;  1Q6S A;  3QCK A;  3ZM2 A;  3QKQ A;  1OEO X;  1U24 A;  2B07 A;  2QCJ A;  1JBV A;  3ZM5 A;  2HY3 A;  3S4E A;  2NTA A;  3F9A A;  1R6H A;  4UAG A;  3UAG A;  5KA0 A;  3QCC A;  5KA8 A;  3LK7 A;  1OET A;  1QXK A;  2NLK A;  2CNF A;  1E0D A;  4OHD A;  2B4U A;  4HJP A;  4ZI4 A;  3QCD A;  3O4U A;  4TVV A;  1Q6P A;  4R0S A;  3I80 A;  1XBO A;  1G7F A;  4KYQ A;  2I4G A;  4QBW A;  3EB1 A;  1NO6 A;  2DXP A;  2F6V A;  5IBS A;  3EZZ A;  1WCH A;  2PT0 A;  2J16 B;  1PTY A;  2I6I A;  4JMJ A;  5KAD A;  5EHP A;  3ZV2 A;  4WU3 A;  4R0T A;  3B7O A;  2UUP A;  1GQQ A;  3PS5 A;  4JNB A;  3S3E A;  4GRZ A;  2CNI A;  2CFV A;  2VEU A;  1OHE A;  2FJN A;  2AHS A;  3QCI A;  3F99 A;  2VEX A;  1NZ7 A;  2H4K A;  2ZN7 A;  3QCG A;  1YGR A;  2J17 A;  3EMU A;  1G1H A;  1XRI A;  2A8B A;  1AAX A;  4WU2 A;  4QUM A;  3QCE A;  2GC6 A;  2B4O A;  2I4E A;  4B04 A;  2I4H A;  2CNH A;  2GC5 A;  1PTV A;  3QCH A;  5IBM A;  3MMJ A;  2BV5 A;  2F6T A;  3D1H A;  1GWZ A;  4BPC A;  4D3Q A;  5A5E A;  5A5F A;  2CM7 A;  1J6U A;  4D3P A;  5K23 A;  2GCB A;  5KA3 A;  3D9C A;  1U26 A;  1PYN A;  3V0E A;  3QCB A;  1ONY A;  3ZMP A;  1YPT A;  1JLN A;  2I6P A;  3N0A A;  2Y67 A;  4ERC A;  1E8C A;  1PXH A;  4GE2 A;  4QDI A;  4BUC A;  4BUB A;  3D1O A;  2G59 A;  3BLU A;  2RF6 A;  2R0B A;  2QDP A;  4HJQ A;  5HDE A;  2CJZ A;  4Z6B A;  1X24 A;  3S4O A;  2VTE A;  3OMH A;  1XXP A;  5AWX A;  2HVL A;  2B3O A;  1GG4 A;  1C83 A;  5K9W A;  1KAV A;  2FJM A;  1ZCL A;  3O4S A;  1EEO A;  1Q6T A;  2VEW A;  3GXG A;  3S3K A;  2I75 A;  4GS0 A;  2I3R A;  5KA9 A;  2NV5 A;  1VHR A;  3V0H A;  4ZN5 A;  5KAB A;  2P4D A;  4YAA A;  2NT2 A;  1FGS A;  2B4P A;  3M4U A;  1OHC A;  1G4U S;  1O5Z A;  1PA9 A;  4PVG A;  2QBR A;  4QBE A;  4J51 A;  1YGU A;  4D3R A;  3BLT A;  2Y1O A;  2AM2 A;  2I6M A;  1FPZ A;  2Q47 A;  4QAP A;  2XJA A;  3AWF A;  2BGD A;  4H34 A;  3LJ8 A;  4IKC A;  4AZ1 A;  4C12 A;  3QCZ A;  3ZM3 A;  2F00 A;  1I57 A;  5KA1 A;  2CNE A;  2WTZ A;  4ZRT A;  2X5O A;  4MBB A;  2F6W A;  2QDC A;  2BZL A;  2I1Y A;  5I6V A;  5K24 A;  4CVK A;  2G6Z A;  4RI5 A;  1C88 A;  2YDU A;  2P6X A;  2VTD A;  1JBW A;  3MOZ A;  3O3L A;  5BX1 A;  2Q05 A;  2E0T A;  2B49 A;  2H03 A;  3V0F A;  3QKP A;  2OZ5 A;  2H4G A;  4YR8 B;  2CMA A;  2AZR A;  4WOH A;  2BGE A;  2QEP A;  5KA7 A;  1C85 A;  1ZCK A;  4Y14 A;  1PA1 A;  2NT7 A;  4RI4 A;  2H4V A;  3ZMQ A;  4DGX A;  5KAC A;  2IMG A;  3RO1 A;  4S0G A;  3QCL A;  4OHE A;  1NWL A;  5BUG A;  2CMC A;  2QCT A;  3ZM0 A;  1QZ0 A;  2JFH A;  1WRM A;  1U25 A;  2HCM A;  3QCM A;  4GFU A;  4CVL A;  2WGP A;  1RXD A;  1YTN A;  2QBS A;  2B4S A;  4KI9 A;  4WTY A;  5K9V A;  2I6J A;  3O5X A;  3QCJ A;  4RKK A;  2PBN A;  1GQY A;  2VEV A;  2VOS A;  4ICZ A;  1V3A A;  2XPC A;  1OHD A;  5MMZ B;  1P31 A;  2PSZ A;  3MVN A;  2WJP A;  5K25 A;  2PA5 A;  2Y66 A;  3BM8 A;  1BZJ A;  1T49 A;  3V0G A;  3GXH A;  1W7K A;  4HRF A;  5K22 A;  2I5X A;  3EU0 A;  2H02 A;  1OEV A;  2HB1 A;  1OES A;  2CMB A;  4GWF A;  3RGQ A;  3BRH A;  1YN9 A;  1Q6N A;  5J8R A;  1ZZW A;  3U96 A;  1MKP A;  2SHP A;  1UAG A;  4GRY A;  1EEH A;  4KYR A;  3ZM6 A;  4QF5 A;  2Y68 A;  1YWF A;  3A5K A;  1D5R A;  4RH9 A;  5BZX A;  1I9T A;  2OOQ A;  2F70 A;  2BIJ A;  3I7Z A;  3S3H A;  5KA2 A;  2ZMM A;  4JBC A;  4GFV A;  3PYZ A;  2Y2F A;  2JJD A;  3A5J A;  5M43 A;  2FH7 A;  1SUG A;  3ZL8 A;  5LXQ B;  3RGO A;  2CM2 A;  2A3K A;  3CM3 A;  4I8N A;  1L8K A;  2VEY A;  1XM2 A;  3SR9 A;  1ECV A;  2GP0 A;  4GE5 A;  4RHG A; 
#chains in the Genus database with same CATH homology
 3D42 A;  1Q6M A;  2I3U A;  2C46 A;  1LQF A;  1ZC0 A;  5GTJ A;  4NX8 A;  1PTU A;  2GWO A;  1GFY A;  1G1F A;  3F41 A;  1EEN A;  4OHH A;  2Y96 A;  1LYV A;  2PI7 A;  3CWE A;  4QAH A;  1L8G A;  3QCF A;  1Q6J A;  5EHR A;  1I9S A;  1OEM X;  1PH0 A;  3D1Q A;  4NND A;  5KAA A;  2OC3 A;  4OHL A;  3S3F A;  1T48 A;  2QBQ A;  2F6Z A;  4DGP A;  5KA4 A;  4Y2E A;  1T4J A;  1G4W R;  4NWG A;  2HNQ A;  1C87 A;  1Q1M A;  3F81 A;  2I6O A;  2MBC A;  4RDD A;  4R30 A;  3NME A;  1NNY A;  3D44 A;  2F46 A;  2HC2 A;  2F6Y A;  3RZ2 A;  2OUD A;  1PTT A;  1YTW A;  3AWG A;  1A5Y A;  1ONZ A;  2H04 A;  3V0J A;  1BZC A;  4NYH A;  1FQ1 A;  4PYH A;  3QCN A;  2CM8 A;  4OHI A;  3AWE A;  1RPM A;  1XXV A;  2CNG A;  2QBP A;  1P15 A;  5BZZ A;  2NZ6 A;  3SME A;  3ZM1 A;  2GJT A;  2ESB A;  1OEU A;  1FPR A;  1C84 A;  3I36 A;  2I42 A;  4JMK A;  3OLR A;  4QUN A;  3EAX A;  3H2X A;  1YFO A;  4GE6 A;  3V0I A;  1NL9 A;  1WAX A;  4H1O A;  2HC1 A;  3F9B A;  4RH5 A;  2F6F A;  2QDM A;  2HNP A;  1M3G A;  1YZ4 A;  2J16 A;  3O4T A;  1BZH A;  2M3V A;  2C7S A;  2PQ5 A;  1NWE A;  1J4X A;  1KAK A;  3V0D A;  1G7G A;  2HXP A;  2F71 A;  4NWF A;  4BJO A;  3MOW A;  1C86 A;  1YTS A;  1G1G A;  1JF7 A;  1LAR A;  2CM3 A;  1Q6S A;  3QCK A;  3ZM2 A;  3QKQ A;  1OEO X;  1U24 A;  2B07 A;  2QCJ A;  2HY3 A;  3S4E A;  2NTA A;  3F9A A;  1R6H A;  5KA0 A;  3QCC A;  5KA8 A;  1OET A;  1QXK A;  2NLK A;  2CNF A;  4OHD A;  2B4U A;  4HJP A;  4ZI4 A;  3QCD A;  3O4U A;  4TVV A;  1Q6P A;  4R0S A;  3I80 A;  1XBO A;  1G7F A;  4KYQ A;  2I4G A;  4QBW A;  3EB1 A;  1NO6 A;  2DXP A;  2F6V A;  5IBS A;  3EZZ A;  1WCH A;  2PT0 A;  2J16 B;  1PTY A;  2I6I A;  4JMJ A;  5KAD A;  5EHP A;  3ZV2 A;  4WU3 A;  4R0T A;  3B7O A;  3PS5 A;  4JNB A;  3S3E A;  4GRZ A;  2CNI A;  2CFV A;  2VEU A;  1OHE A;  2FJN A;  2AHS A;  3QCI A;  3F99 A;  2VEX A;  1NZ7 A;  2H4K A;  2ZN7 A;  3QCG A;  1YGR A;  2J17 A;  3EMU A;  1G1H A;  1XRI A;  2A8B A;  1AAX A;  4WU2 A;  4QUM A;  3QCE A;  2B4O A;  2I4E A;  4B04 A;  2I4H A;  2CNH A;  1PTV A;  3QCH A;  5IBM A;  3MMJ A;  2BV5 A;  2F6T A;  3D1H A;  1GWZ A;  4BPC A;  4D3Q A;  2CM7 A;  4D3P A;  5K23 A;  5KA3 A;  3D9C A;  1U26 A;  1PYN A;  3V0E A;  3QCB A;  1ONY A;  3ZMP A;  1YPT A;  1JLN A;  2I6P A;  3N0A A;  4ERC A;  1PXH A;  4GE2 A;  3D1O A;  2G59 A;  3BLU A;  2RF6 A;  2R0B A;  2QDP A;  4HJQ A;  5HDE A;  2CJZ A;  4Z6B A;  1X24 A;  3S4O A;  3OMH A;  1XXP A;  5AWX A;  2HVL A;  2B3O A;  1C83 A;  5K9W A;  1KAV A;  2FJM A;  1ZCL A;  3O4S A;  1EEO A;  1Q6T A;  2VEW A;  3GXG A;  3S3K A;  2I75 A;  4GS0 A;  2I3R A;  5KA9 A;  2NV5 A;  1VHR A;  3V0H A;  4ZN5 A;  5KAB A;  2P4D A;  4YAA A;  2NT2 A;  2B4P A;  3M4U A;  1OHC A;  1G4U S;  1PA9 A;  4PVG A;  2QBR A;  4QBE A;  4J51 A;  1YGU A;  4D3R A;  3BLT A;  2I6M A;  1FPZ A;  2Q47 A;  4QAP A;  3AWF A;  2BGD A;  4H34 A;  3LJ8 A;  4IKC A;  4AZ1 A;  3ZM3 A;  1I57 A;  5KA1 A;  2CNE A;  4ZRT A;  4MBB A;  2F6W A;  2QDC A;  2BZL A;  2I1Y A;  5I6V A;  5K24 A;  2G6Z A;  4RI5 A;  1C88 A;  2YDU A;  2P6X A;  3MOZ A;  3O3L A;  5BX1 A;  2Q05 A;  2E0T A;  2B49 A;  2H03 A;  3V0F A;  3QKP A;  2OZ5 A;  2H4G A;  4YR8 B;  2CMA A;  2AZR A;  4WOH A;  2BGE A;  2QEP A;  5KA7 A;  1C85 A;  1ZCK A;  4Y14 A;  1PA1 A;  2NT7 A;  4RI4 A;  2H4V A;  3ZMQ A;  4DGX A;  5KAC A;  2IMG A;  3RO1 A;  4S0G A;  3QCL A;  4OHE A;  1NWL A;  5BUG A;  2CMC A;  2QCT A;  3ZM0 A;  1QZ0 A;  1WRM A;  1U25 A;  2HCM A;  3QCM A;  4GFU A;  2WGP A;  1RXD A;  1YTN A;  2QBS A;  2B4S A;  4KI9 A;  4WTY A;  5K9V A;  2I6J A;  3O5X A;  3QCJ A;  4RKK A;  2PBN A;  2VEV A;  4ICZ A;  1V3A A;  1OHD A;  5MMZ B;  2PSZ A;  5K25 A;  2PA5 A;  3BM8 A;  1BZJ A;  1T49 A;  3V0G A;  3GXH A;  4HRF A;  5K22 A;  2I5X A;  3EU0 A;  2H02 A;  1OEV A;  2HB1 A;  1OES A;  2CMB A;  4GWF A;  3RGQ A;  3BRH A;  1YN9 A;  1Q6N A;  5J8R A;  1ZZW A;  3U96 A;  1MKP A;  2SHP A;  4GRY A;  4KYR A;  1YWF A;  3A5K A;  1D5R A;  4RH9 A;  5BZX A;  1I9T A;  2OOQ A;  2F70 A;  2BIJ A;  3I7Z A;  3S3H A;  5KA2 A;  2ZMM A;  4JBC A;  4GFV A;  2Y2F A;  2JJD A;  3A5J A;  5M43 A;  2FH7 A;  1SUG A;  5LXQ B;  3RGO A;  2CM2 A;  2A3K A;  3CM3 A;  4I8N A;  1L8K A;  2VEY A;  1XM2 A;  3SR9 A;  1ECV A;  2GP0 A;  4GE5 A;  4RHG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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