3CWEA

Ptp1b in complex with a phosphonic acid inhibitor
Total Genus 105
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
290
structure length
285
Chain Sequence
AADKLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 105
structure length 285
sequence length 290
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3cweA00
2FJMA 4RH5A 4GWFA 3QCCA 1M3GA 5IBSA 2I6JA 2F6WA 3O3LA 4RI5A 5K9VA 4RKKA 1X24A 5KABA 3CWEA 2CNEA 5HDEA 4HRFA 2VEUA 4ZRTA 4D3PA 4JMKA 2B4PA 2HC1A 2I75A 2FJNA 1GWZA 3QCNA 2CMCA 3PS5A 5I6VA 4D3RA 4JMJA 3MOWA 1Q6JA 4QAPA 4GFUA 2I5XA 1G4US 2HY3A 3MMJA 2B4SA 2CNHA 1PYNA 2OZ5A 2NV5A 2I4GA 1G1GA 2B07A 1C87A 2QCTA 5GTJA 2PSZA 3AWFA 3RO1A 5LXQB 1I9TA 1ONZA 2MBCA 1D5RA 3QCBA 3NMEA 4Z6BA 5K9WA 2VEYA 4RI4A 1QZ0A 3GXHA 1U24A 2B49A 2Q47A 3EB1A 4QUNA 2HC2A 4D3QA 5KA0A 1C86A 1GFYA 2Q05A 2GWOA 1L8GA 1OEVA 2BV5A 3O4TA 3SR9A 1Q6TA 4OHHA 3QCDA 3V0IA 1YWFA 2CM2A 1RPMA 2RF6A 2BIJA 4H34A 4KYRA 5KA9A 3QCMA 1BZJA 4PYHA 1P15A 3F9BA 1C85A 4J51A 3QCJA 2NZ6A 5MMZB 2HNPA 4Y14A 2E0TA 4NYHA 1LARA 2H4GA 1I9SA 4OHDA 4YAAA 1G7FA 3RZ2A 1PH0A 4MBBA 1PA9A 4ERCA 4DGPA 1R6HA 2H03A 4KYQA 2BGEA 3ZM3A 2HXPA 2I42A 4NNDA 3H2XA 1LYVA 2I6PA 4Y2EA 1Q1MA 2QDCA 1KAKA 3N0AA 3EAXA 3BLTA 2C46A 1ZC0A 2CNGA 3D1OA 4H1OA 3V0DA 4GRYA 1ECVA 2B3OA 3BRHA 1G1HA 2CM7A 1FPZA 3BLUA 2I4HA 3CM3A 5K23A 3OLRA 3S3KA 2G6ZA 2PI7A 2NT7A 2HB1A 1WRMA 2H4VA 2AHSA 2I3RA 1T48A 3D1QA 3MOZA 1NL9A 4B04A 1EENA 3QCLA 5KADA 2NTAA 4S0GA 2CM8A 4ICZA 5KA1A 2CNFA 1FPRA 1VHRA 1OHCA 2R0BA 2CMAA 4GE5A 2OC3A 2I4EA 3LJ8A 2QBRA 2J17A 2QCJA 1V3AA 3A5KA 3ZMPA 3S4EA 2G59A 2JJDA 2P6XA 3D44A 4RDDA 2HVLA 2M3VA 2ZMMA 2DXPA 5K22A 5KACA 3ZM1A 1ZZWA 1Q6SA 2ESBA 5M43A 1RXDA 2OUDA 2HNQA 2H4KA 1YTWA 4HJPA 4WU2A 1JLNA 3EMUA 3F81A 4IKCA 5BUGA 3F99A 1PTVA 1YPTA 5EHRA 3D1HA 4ZI4A 1PXHA 5K24A 4HJQA 2CFVA 5EHPA 2SHPA 2B4OA 1Q6NA 1G7GA 1YN9A 5KA7A 3V0EA 1NNYA 1J4XA 5BZZA 3D42A 4R30A 2PBNA 3EU0A 4BPCA 2GP0A 1T49A 1XM2A 2I6IA 2F6FA 3I80A 3QCFA 1XXPA 2QBSA 3RGOA 3S3EA 2BZLA 4TVVA 3BM8A 4R0SA 3V0FA 3QKQA 2A3KA 2I6MA 2AZRA 2C7SA 3ZM0A 2F6VA 4JNBA 4BJOA 1QXKA 1AAXA 3GXGA 1YTSA 1NO6A 1ZCKA 3OMHA 5J8RA 1FQ1A 4OHIA 1NWLA 2CNIA 2IMGA 1PTUA 1OHDA 2QBQA 4QBEA 1T4JA 2H02A 2F70A 1ONYA 5KA3A 1WAXA 3O5XA 4WU3A 2BGDA 3QKPA 4NWFA 4WTYA 1LQFA 3AWEA 1C84A 5KA2A 1EEOA 5BZXA 1I57A 5KAAA 2CM3A 1L8KA 2NT2A 3I7ZA 2I6OA 5KA4A 3O4UA 1XRIA 4NX8A 3AWGA 4GFVA 4WOHA 1A5YA 3S4OA 2VEWA 3ZMQA 1JF7A 5BX1A 1KAVA 3F9AA 2NLKA 4KI9A 4AZ1A 2PT0A 3D9CA 3RGQA 2F71A 3QCKA 3SMEA 5K25A 3A5JA 1BZHA 3F41A 2F6TA 4RH9A 4OHLA 2PQ5A 1PTTA 3EZZA 4YR8B 3B7OA 2A8BA 1PA1A 4RHGA 1YGRA 5KA8A 2P4DA 1BZCA 2GJTA 3ZV2A 1PTYA 3QCHA 1OEUA 4I8NA 2CJZA 3ZM2A 1OHEA 3QCIA 1ZCLA 5AWXA 2I3UA 1WCHA 1Q6MA 2QDMA 4JBCA 4DGXA 1XBOA 1YZ4A 3QCEA 3QCGA 4QUMA 4GS0A 2F46A 2WGPA 4GE2A 1YGUA 2OOQA 1U26A 4GE6A 2YDUA 1OEOX 2J16B 5IBMA 3S3FA 1SUGA 1MKPA 1OETA 4QBWA 1G1FA 2F6ZA 2J16A 1C88A 3V0HA 2QEPA 4GRZA 3M4UA 3V0JA 1G4WR 2B4UA 2VEXA 2I1YA 4ZN5A 3S3HA 2QBPA 3I36A 4QAHA 4R0TA 1OESA 4PVGA 1XXVA 1YTNA 2VEVA 1NWEA 1C83A 2PA5A 1OEMX 3V0GA 2QDPA 1Q6PA 2Y2FA 4OHEA 1U25A 2HCMA 3O4SA 2H04A 1NZ7A 2Y96A 2CMBA 4NWGA 2FH7A 1YFOA 3U96A 2F6YA 2ZN7A
chains in the Genus database with same CATH superfamily
2FJMA 4RH5A 1FGSA 4GWFA 3QCCA 1M3GA 5IBSA 2I6JA 2F6WA 3O3LA 4RI5A 5K9VA 4RKKA 1X24A 5KABA 1J6UA 3CWEA 2CNEA 5HDEA 4HRFA 2VORA 2Y68A 2VEUA 4ZRTA 4D3PA 4JMKA 2B4PA 2HC1A 2I75A 2FJNA 1GWZA 3QCNA 2CMCA 3PS5A 5I6VA 4D3RA 4JMJA 3MOWA 1Q6JA 4QAPA 4GFUA 2I5XA 1G4US 2HY3A 3MMJA 2B4SA 2CNHA 1PYNA 2OZ5A 2NV5A 2I4GA 1G1GA 2B07A 1C87A 2XPCA 2QCTA 5GTJA 2PSZA 3AWFA 3RO1A 5LXQB 1I9TA 2Y67A 1JBWA 1ONZA 1O5ZA 2MBCA 1D5RA 3QCBA 3NMEA 4Z6BA 5K9WA 2VEYA 4RI4A 1QZ0A 3GXHA 1U24A 2B49A 2Q47A 3EB1A 2X5OA 2HC2A 4QUNA 4D3QA 5KA0A 1C86A 1GFYA 2Q05A 2GWOA 1L8GA 1GG4A 1OEVA 5A5EA 2BV5A 3O4TA 3SR9A 1Q6TA 4OHHA 3QCDA 3V0IA 1YWFA 2CM2A 1RPMA 2RF6A 4QDIA 2BIJA 4H34A 4KYRA 5KA9A 3QCMA 1BZJA 4PYHA 1P15A 3F9BA 1C85A 4J51A 3QCJA 2NZ6A 5MMZB 2GCBA 2HNPA 4Y14A 2E0TA 4NYHA 1LARA 2H4GA 1I9SA 4OHDA 4YAAA 1G7FA 3RZ2A 1PH0A 4MBBA 2JFFA 1PA9A 4ERCA 4DGPA 1R6HA 2H03A 4KYQA 2BGEA 3ZM3A 2HXPA 2I42A 4NNDA 3H2XA 1LYVA 2I6PA 4Y2EA 1Q1MA 2QDCA 1KAKA 3N0AA 3EAXA 3BLTA 3ZM6A 2C46A 1ZC0A 2CNGA 3D1OA 4H1OA 3UAGA 3V0DA 4GRYA 1ECVA 2B3OA 3BRHA 1G1HA 2CM7A 2GC6A 1FPZA 3BLUA 2I4HA 3CM3A 5K23A 4HV4A 3OLRA 3S3KA 2G6ZA 2PI7A 2NT7A 2HB1A 1WRMA 2H4VA 2AHSA 2I3RA 1T48A 3D1QA 3MOZA 1NL9A 4B04A 2AM2A 2WJPA 1EENA 3QCLA 5KADA 2NTAA 4S0GA 2CM8A 4ICZA 3HN7A 5KA1A 2CNFA 1FPRA 1VHRA 1OHCA 3ZL8A 2R0BA 2CMAA 4GE5A 1JBVA 2OC3A 2I4EA 3LJ8A 2GC5A 2QBRA 2J17A 1GQYA 2QCJA 1V3AA 3A5KA 3ZMPA 2XJAA 2G59A 3S4EA 2JJDA 2P6XA 3D44A 2Y66A 4RDDA 2HVLA 2M3VA 2ZMMA 2DXPA 5K22A 5KACA 3ZM1A 1ZZWA 1Q6SA 2ESBA 1EEHA 5A5FA 5M43A 1RXDA 1E8CA 2OUDA 2HNQA 1P31A 2H4KA 1YTWA 3N2AA 2JFGA 4HJPA 4WU2A 1JLNA 3EMUA 3F81A 4IKCA 5BUGA 3F99A 4CVKA 1PTVA 1YPTA 5EHRA 3D1HA 4ZI4A 1PXHA 5K24A 4HJQA 2CFVA 5EHPA 2SHPA 4C13A 2B4OA 1Q6NA 1G7GA 1YN9A 5KA7A 3V0EA 1NNYA 4BUCA 4ZIYA 1J4XA 5BZZA 4CVMA 3D42A 4R30A 2PBNA 1P3DA 3EU0A 4BPCA 2GP0A 1T49A 1XM2A 3PYZA 2I6IA 2F6FA 3I80A 3QCFA 2F00A 1XXPA 2QBSA 3RGOA 3S3EA 2BZLA 4TVVA 3BM8A 4R0SA 3V0FA 3QKQA 2A3KA 2I6MA 2AZRA 2C7SA 3ZM0A 2F6VA 4JNBA 4BJOA 1QXKA 1AAXA 3GXGA 1YTSA 1NO6A 1ZCKA 3OMHA 2AM1A 5J8RA 1FQ1A 4OHIA 1NWLA 2CNIA 2IMGA 1PTUA 1OHDA 2QBQA 4QBEA 1T4JA 2H02A 2F70A 1ONYA 5KA3A 3LK7A 1WAXA 3O5XA 4WU3A 2BGDA 3QKPA 4NWFA 4WTYA 3ZM5A 1LQFA 3AWEA 1C84A 5KA2A 1EEOA 2VOSA 5BZXA 1I57A 5KAAA 2CM3A 1L8KA 2NT2A 3I7ZA 2I6OA 5KA4A 3O4UA 1XRIA 4NX8A 2UUPA 3AWGA 4GFVA 4WOHA 1A5YA 3S4OA 2VEWA 3ZMQA 1JF7A 5BX1A 4CVLA 1KAVA 3F9AA 2NLKA 4KI9A 4AZ1A 2PT0A 3D9CA 3RGQA 2F71A 3QCKA 1UAGA 3SMEA 5K25A 2JFHA 1BZHA 3A5JA 2F6TA 3F41A 4RH9A 4UAGA 4OHLA 2PQ5A 1PTTA 3EZZA 4YR8B 3B7OA 2A8BA 1PA1A 4RHGA 1YGRA 5KA8A 2P4DA 1BZCA 2GJTA 3ZV2A 1PTYA 1W78A 3QCHA 4C12A 4BUBA 1OEUA 4I8NA 2CJZA 3ZM2A 1OHEA 3QCIA 1ZCLA 5AWXA 2I3UA 1WCHA 1Q6MA 2QDMA 4JBCA 4DGXA 1XBOA 1YZ4A 3QCEA 1E0DA 3QCGA 4QUMA 2VTEA 4GS0A 2F46A 2WGPA 4GE2A 1YGUA 3MVNA 2OOQA 2WTZA 1U26A 4GE6A 2YDUA 1OEOX 2J16B 5IBMA 3S3FA 2UUOA 1SUGA 1MKPA 1OETA 4QBWA 1G1FA 2UAGA 2F6ZA 2J16A 1C88A 4QF5A 3V0HA 2QEPA 4GRZA 3M4UA 3V0JA 1G4WR 2B4UA 2VEXA 2I1YA 4ZN5A 3S3HA 2QBPA 3I36A 4QAHA 4R0TA 3QCZA 1OESA 4PVGA 1XXVA 1YTNA 2VEVA 2Y1OA 1NWEA 1C83A 2VTDA 2PA5A 1OEMX 3V0GA 2QDPA 1Q6PA 3NRSA 1GQQA 2GCAA 2Y2FA 4OHEA 1U25A 2HCMA 3O4SA 2H04A 1NZ7A 1W7KA 2Y96A 2CMBA 4NWGA 2FH7A 1YFOA 3U96A 2F6YA 2ZN7A
chains in the Genus database with same CATH topology
2FJMA 4RH5A 4GWFA 3QCCA 1M3GA 5IBSA 2I6JA 2F6WA 3O3LA 4RI5A 5K9VA 4RKKA 1X24A 5KABA 3CWEA 2CNEA 5HDEA 4HRFA 2VEUA 4ZRTA 4D3PA 4JMKA 2B4PA 2HC1A 2I75A 2FJNA 1GWZA 3QCNA 2CMCA 3PS5A 5I6VA 4D3RA 4JMJA 3MOWA 1Q6JA 4QAPA 4GFUA 2I5XA 1G4US 2HY3A 3MMJA 2B4SA 2CNHA 1PYNA 2OZ5A 2NV5A 2I4GA 1G1GA 2B07A 1C87A 2QCTA 5GTJA 2PSZA 3AWFA 3RO1A 5LXQB 1I9TA 1ONZA 2MBCA 1D5RA 3QCBA 3NMEA 4Z6BA 5K9WA 2VEYA 4RI4A 1QZ0A 3GXHA 1U24A 2B49A 2Q47A 3EB1A 4QUNA 2HC2A 4D3QA 5KA0A 1C86A 1GFYA 2Q05A 2GWOA 1L8GA 1OEVA 2BV5A 3O4TA 3SR9A 1Q6TA 4OHHA 3QCDA 3V0IA 1YWFA 2CM2A 1RPMA 2RF6A 2BIJA 4H34A 4KYRA 5KA9A 3QCMA 1BZJA 4PYHA 1P15A 3F9BA 1C85A 4J51A 3QCJA 2NZ6A 5MMZB 2HNPA 4Y14A 2E0TA 4NYHA 1LARA 2H4GA 1I9SA 4OHDA 4YAAA 1G7FA 3RZ2A 1PH0A 4MBBA 1PA9A 4ERCA 4DGPA 1R6HA 2H03A 4KYQA 2BGEA 3ZM3A 2HXPA 2I42A 4NNDA 3H2XA 1LYVA 2I6PA 4Y2EA 1Q1MA 2QDCA 1KAKA 3N0AA 3EAXA 3BLTA 2C46A 1ZC0A 2CNGA 3D1OA 4H1OA 3V0DA 4GRYA 1ECVA 2B3OA 3BRHA 1G1HA 2CM7A 1FPZA 3BLUA 2I4HA 3CM3A 5K23A 3OLRA 3S3KA 2G6ZA 2PI7A 2NT7A 2HB1A 1WRMA 2H4VA 2AHSA 2I3RA 1T48A 3D1QA 3MOZA 1NL9A 4B04A 1EENA 3QCLA 5KADA 2NTAA 4S0GA 2CM8A 4ICZA 5KA1A 2CNFA 1FPRA 1VHRA 1OHCA 2R0BA 2CMAA 4GE5A 2OC3A 2I4EA 3LJ8A 2QBRA 2J17A 2QCJA 1V3AA 3A5KA 3ZMPA 3S4EA 2G59A 2JJDA 2P6XA 3D44A 4RDDA 2HVLA 2M3VA 2ZMMA 2DXPA 5K22A 5KACA 3ZM1A 1ZZWA 1Q6SA 2ESBA 5M43A 1RXDA 2OUDA 2HNQA 2H4KA 1YTWA 4HJPA 4WU2A 1JLNA 3EMUA 3F81A 4IKCA 5BUGA 3F99A 1PTVA 1YPTA 5EHRA 3D1HA 4ZI4A 1PXHA 5K24A 4HJQA 2CFVA 5EHPA 2SHPA 2B4OA 1Q6NA 1G7GA 1YN9A 5KA7A 3V0EA 1NNYA 1J4XA 5BZZA 3D42A 4R30A 2PBNA 3EU0A 4BPCA 2GP0A 1T49A 1XM2A 2I6IA 2F6FA 3I80A 3QCFA 1XXPA 2QBSA 3RGOA 3S3EA 2BZLA 4TVVA 3BM8A 4R0SA 3V0FA 3QKQA 2A3KA 2I6MA 2AZRA 2C7SA 3ZM0A 2F6VA 4JNBA 4BJOA 1QXKA 1AAXA 3GXGA 1YTSA 1NO6A 1ZCKA 3OMHA 5J8RA 1FQ1A 4OHIA 1NWLA 2CNIA 2IMGA 1PTUA 1OHDA 2QBQA 4QBEA 1T4JA 2H02A 2F70A 1ONYA 5KA3A 1WAXA 3O5XA 4WU3A 2BGDA 3QKPA 4NWFA 4WTYA 1LQFA 3AWEA 1C84A 5KA2A 1EEOA 5BZXA 1I57A 5KAAA 2CM3A 1L8KA 2NT2A 3I7ZA 2I6OA 5KA4A 3O4UA 1XRIA 4NX8A 3AWGA 4GFVA 4WOHA 1A5YA 3S4OA 2VEWA 3ZMQA 1JF7A 5BX1A 1KAVA 3F9AA 2NLKA 4KI9A 4AZ1A 2PT0A 3D9CA 3RGQA 2F71A 3QCKA 3SMEA 5K25A 3A5JA 1BZHA 3F41A 2F6TA 4RH9A 4OHLA 2PQ5A 1PTTA 3EZZA 4YR8B 3B7OA 2A8BA 1PA1A 4RHGA 1YGRA 5KA8A 2P4DA 1BZCA 2GJTA 3ZV2A 1PTYA 3QCHA 1OEUA 4I8NA 2CJZA 3ZM2A 1OHEA 3QCIA 1ZCLA 5AWXA 2I3UA 1WCHA 1Q6MA 2QDMA 4JBCA 4DGXA 1XBOA 1YZ4A 3QCEA 3QCGA 4QUMA 4GS0A 2F46A 2WGPA 4GE2A 1YGUA 2OOQA 1U26A 4GE6A 2YDUA 1OEOX 2J16B 5IBMA 3S3FA 1SUGA 1MKPA 1OETA 4QBWA 1G1FA 2F6ZA 2J16A 1C88A 3V0HA 2QEPA 4GRZA 3M4UA 3V0JA 1G4WR 2B4UA 2VEXA 2I1YA 4ZN5A 3S3HA 2QBPA 3I36A 4QAHA 4R0TA 1OESA 4PVGA 1XXVA 1YTNA 2VEVA 1NWEA 1C83A 2PA5A 1OEMX 3V0GA 2QDPA 1Q6PA 2Y2FA 4OHEA 1U25A 2HCMA 3O4SA 2H04A 1NZ7A 2Y96A 2CMBA 4NWGA 2FH7A 1YFOA 3U96A 2F6YA 2ZN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FJM A;  4RH5 A;  4GWF A;  3QCC A;  1M3G A;  5IBS A;  2I6J A;  2F6W A;  3O3L A;  4RI5 A;  5K9V A;  4RKK A;  1X24 A;  5KAB A;  3CWE A;  2CNE A;  5HDE A;  4HRF A;  2VEU A;  4ZRT A;  4D3P A;  4JMK A;  2B4P A;  2HC1 A;  2I75 A;  2FJN A;  1GWZ A;  3QCN A;  2CMC A;  3PS5 A;  5I6V A;  4D3R A;  4JMJ A;  3MOW A;  1Q6J A;  4QAP A;  4GFU A;  2I5X A;  1G4U S;  2HY3 A;  3MMJ A;  2B4S A;  2CNH A;  1PYN A;  2OZ5 A;  2NV5 A;  2I4G A;  1G1G A;  2B07 A;  1C87 A;  2QCT A;  5GTJ A;  2PSZ A;  3AWF A;  3RO1 A;  5LXQ B;  1I9T A;  1ONZ A;  2MBC A;  1D5R A;  3QCB A;  3NME A;  4Z6B A;  5K9W A;  2VEY A;  4RI4 A;  1QZ0 A;  3GXH A;  1U24 A;  2B49 A;  2Q47 A;  3EB1 A;  4QUN A;  2HC2 A;  4D3Q A;  5KA0 A;  1C86 A;  1GFY A;  2Q05 A;  2GWO A;  1L8G A;  1OEV A;  2BV5 A;  3O4T A;  3SR9 A;  1Q6T A;  4OHH A;  3QCD A;  3V0I A;  1YWF A;  2CM2 A;  1RPM A;  2RF6 A;  2BIJ A;  4H34 A;  4KYR A;  5KA9 A;  3QCM A;  1BZJ A;  4PYH A;  1P15 A;  3F9B A;  1C85 A;  4J51 A;  3QCJ A;  2NZ6 A;  5MMZ B;  2HNP A;  4Y14 A;  2E0T A;  4NYH A;  1LAR A;  2H4G A;  1I9S A;  4OHD A;  4YAA A;  1G7F A;  3RZ2 A;  1PH0 A;  4MBB A;  1PA9 A;  4ERC A;  4DGP A;  1R6H A;  2H03 A;  4KYQ A;  2BGE A;  3ZM3 A;  2HXP A;  2I42 A;  4NND A;  3H2X A;  1LYV A;  2I6P A;  4Y2E A;  1Q1M A;  2QDC A;  1KAK A;  3N0A A;  3EAX A;  3BLT A;  2C46 A;  1ZC0 A;  2CNG A;  3D1O A;  4H1O A;  3V0D A;  4GRY A;  1ECV A;  2B3O A;  3BRH A;  1G1H A;  2CM7 A;  1FPZ A;  3BLU A;  2I4H A;  3CM3 A;  5K23 A;  3OLR A;  3S3K A;  2G6Z A;  2PI7 A;  2NT7 A;  2HB1 A;  1WRM A;  2H4V A;  2AHS A;  2I3R A;  1T48 A;  3D1Q A;  3MOZ A;  1NL9 A;  4B04 A;  1EEN A;  3QCL A;  5KAD A;  2NTA A;  4S0G A;  2CM8 A;  4ICZ A;  5KA1 A;  2CNF A;  1FPR A;  1VHR A;  1OHC A;  2R0B A;  2CMA A;  4GE5 A;  2OC3 A;  2I4E A;  3LJ8 A;  2QBR A;  2J17 A;  2QCJ A;  1V3A A;  3A5K A;  3ZMP A;  3S4E A;  2G59 A;  2JJD A;  2P6X A;  3D44 A;  4RDD A;  2HVL A;  2M3V A;  2ZMM A;  2DXP A;  5K22 A;  5KAC A;  3ZM1 A;  1ZZW A;  1Q6S A;  2ESB A;  5M43 A;  1RXD A;  2OUD A;  2HNQ A;  2H4K A;  1YTW A;  4HJP A;  4WU2 A;  1JLN A;  3EMU A;  3F81 A;  4IKC A;  5BUG A;  3F99 A;  1PTV A;  1YPT A;  5EHR A;  3D1H A;  4ZI4 A;  1PXH A;  5K24 A;  4HJQ A;  2CFV A;  5EHP A;  2SHP A;  2B4O A;  1Q6N A;  1G7G A;  1YN9 A;  5KA7 A;  3V0E A;  1NNY A;  1J4X A;  5BZZ A;  3D42 A;  4R30 A;  2PBN A;  3EU0 A;  4BPC A;  2GP0 A;  1T49 A;  1XM2 A;  2I6I A;  2F6F A;  3I80 A;  3QCF A;  1XXP A;  2QBS A;  3RGO A;  3S3E A;  2BZL A;  4TVV A;  3BM8 A;  4R0S A;  3V0F A;  3QKQ A;  2A3K A;  2I6M A;  2AZR A;  2C7S A;  3ZM0 A;  2F6V A;  4JNB A;  4BJO A;  1QXK A;  1AAX A;  3GXG A;  1YTS A;  1NO6 A;  1ZCK A;  3OMH A;  5J8R A;  1FQ1 A;  4OHI A;  1NWL A;  2CNI A;  2IMG A;  1PTU A;  1OHD A;  2QBQ A;  4QBE A;  1T4J A;  2H02 A;  2F70 A;  1ONY A;  5KA3 A;  1WAX A;  3O5X A;  4WU3 A;  2BGD A;  3QKP A;  4NWF A;  4WTY A;  1LQF A;  3AWE A;  1C84 A;  5KA2 A;  1EEO A;  5BZX A;  1I57 A;  5KAA A;  2CM3 A;  1L8K A;  2NT2 A;  3I7Z A;  2I6O A;  5KA4 A;  3O4U A;  1XRI A;  4NX8 A;  3AWG A;  4GFV A;  4WOH A;  1A5Y A;  3S4O A;  2VEW A;  3ZMQ A;  1JF7 A;  5BX1 A;  1KAV A;  3F9A A;  2NLK A;  4KI9 A;  4AZ1 A;  2PT0 A;  3D9C A;  3RGQ A;  2F71 A;  3QCK A;  3SME A;  5K25 A;  3A5J A;  1BZH A;  3F41 A;  2F6T A;  4RH9 A;  4OHL A;  2PQ5 A;  1PTT A;  3EZZ A;  4YR8 B;  3B7O A;  2A8B A;  1PA1 A;  4RHG A;  1YGR A;  5KA8 A;  2P4D A;  1BZC A;  2GJT A;  3ZV2 A;  1PTY A;  3QCH A;  1OEU A;  4I8N A;  2CJZ A;  3ZM2 A;  1OHE A;  3QCI A;  1ZCL A;  5AWX A;  2I3U A;  1WCH A;  1Q6M A;  2QDM A;  4JBC A;  4DGX A;  1XBO A;  1YZ4 A;  3QCE A;  3QCG A;  4QUM A;  4GS0 A;  2F46 A;  2WGP A;  4GE2 A;  1YGU A;  2OOQ A;  1U26 A;  4GE6 A;  2YDU A;  1OEO X;  2J16 B;  5IBM A;  3S3F A;  1SUG A;  1MKP A;  1OET A;  4QBW A;  1G1F A;  2F6Z A;  2J16 A;  1C88 A;  3V0H A;  2QEP A;  4GRZ A;  3M4U A;  3V0J A;  1G4W R;  2B4U A;  2VEX A;  2I1Y A;  4ZN5 A;  3S3H A;  2QBP A;  3I36 A;  4QAH A;  4R0T A;  1OES A;  4PVG A;  1XXV A;  1YTN A;  2VEV A;  1NWE A;  1C83 A;  2PA5 A;  1OEM X;  3V0G A;  2QDP A;  1Q6P A;  2Y2F A;  4OHE A;  1U25 A;  2HCM A;  3O4S A;  2H04 A;  1NZ7 A;  2Y96 A;  2CMB A;  4NWG A;  2FH7 A;  1YFO A;  3U96 A;  2F6Y A;  2ZN7 A; 
#chains in the Genus database with same CATH topology
 2FJM A;  4RH5 A;  1FGS A;  4GWF A;  3QCC A;  1M3G A;  5IBS A;  2I6J A;  2F6W A;  3O3L A;  4RI5 A;  5K9V A;  4RKK A;  1X24 A;  5KAB A;  1J6U A;  3CWE A;  2CNE A;  5HDE A;  4HRF A;  2VOR A;  2Y68 A;  2VEU A;  4ZRT A;  4D3P A;  4JMK A;  2B4P A;  2HC1 A;  2I75 A;  2FJN A;  1GWZ A;  3QCN A;  2CMC A;  3PS5 A;  5I6V A;  4D3R A;  4JMJ A;  3MOW A;  1Q6J A;  4QAP A;  4GFU A;  2I5X A;  1G4U S;  2HY3 A;  3MMJ A;  2B4S A;  2CNH A;  1PYN A;  2OZ5 A;  2NV5 A;  2I4G A;  1G1G A;  2B07 A;  1C87 A;  2XPC A;  2QCT A;  5GTJ A;  2PSZ A;  3AWF A;  3RO1 A;  5LXQ B;  1I9T A;  2Y67 A;  1JBW A;  1ONZ A;  1O5Z A;  2MBC A;  1D5R A;  3QCB A;  3NME A;  4Z6B A;  5K9W A;  2VEY A;  4RI4 A;  1QZ0 A;  3GXH A;  1U24 A;  2B49 A;  2Q47 A;  3EB1 A;  2X5O A;  2HC2 A;  4QUN A;  4D3Q A;  5KA0 A;  1C86 A;  1GFY A;  2Q05 A;  2GWO A;  1L8G A;  1GG4 A;  1OEV A;  5A5E A;  2BV5 A;  3O4T A;  3SR9 A;  1Q6T A;  4OHH A;  3QCD A;  3V0I A;  1YWF A;  2CM2 A;  1RPM A;  2RF6 A;  4QDI A;  2BIJ A;  4H34 A;  4KYR A;  5KA9 A;  3QCM A;  1BZJ A;  4PYH A;  1P15 A;  3F9B A;  1C85 A;  4J51 A;  3QCJ A;  2NZ6 A;  5MMZ B;  2GCB A;  2HNP A;  4Y14 A;  2E0T A;  4NYH A;  1LAR A;  2H4G A;  1I9S A;  4OHD A;  4YAA A;  1G7F A;  3RZ2 A;  1PH0 A;  4MBB A;  2JFF A;  1PA9 A;  4ERC A;  4DGP A;  1R6H A;  2H03 A;  4KYQ A;  2BGE A;  3ZM3 A;  2HXP A;  2I42 A;  4NND A;  3H2X A;  1LYV A;  2I6P A;  4Y2E A;  1Q1M A;  2QDC A;  1KAK A;  3N0A A;  3EAX A;  3BLT A;  3ZM6 A;  2C46 A;  1ZC0 A;  2CNG A;  3D1O A;  4H1O A;  3UAG A;  3V0D A;  4GRY A;  1ECV A;  2B3O A;  3BRH A;  1G1H A;  2CM7 A;  2GC6 A;  1FPZ A;  3BLU A;  2I4H A;  3CM3 A;  5K23 A;  4HV4 A;  3OLR A;  3S3K A;  2G6Z A;  2PI7 A;  2NT7 A;  2HB1 A;  1WRM A;  2H4V A;  2AHS A;  2I3R A;  1T48 A;  3D1Q A;  3MOZ A;  1NL9 A;  4B04 A;  2AM2 A;  2WJP A;  1EEN A;  3QCL A;  5KAD A;  2NTA A;  4S0G A;  2CM8 A;  4ICZ A;  3HN7 A;  5KA1 A;  2CNF A;  1FPR A;  1VHR A;  1OHC A;  3ZL8 A;  2R0B A;  2CMA A;  4GE5 A;  1JBV A;  2OC3 A;  2I4E A;  3LJ8 A;  2GC5 A;  2QBR A;  2J17 A;  1GQY A;  2QCJ A;  1V3A A;  3A5K A;  3ZMP A;  2XJA A;  2G59 A;  3S4E A;  2JJD A;  2P6X A;  3D44 A;  2Y66 A;  4RDD A;  2HVL A;  2M3V A;  2ZMM A;  2DXP A;  5K22 A;  5KAC A;  3ZM1 A;  1ZZW A;  1Q6S A;  2ESB A;  1EEH A;  5A5F A;  5M43 A;  1RXD A;  1E8C A;  2OUD A;  2HNQ A;  1P31 A;  2H4K A;  1YTW A;  3N2A A;  2JFG A;  4HJP A;  4WU2 A;  1JLN A;  3EMU A;  3F81 A;  4IKC A;  5BUG A;  3F99 A;  4CVK A;  1PTV A;  1YPT A;  5EHR A;  3D1H A;  4ZI4 A;  1PXH A;  5K24 A;  4HJQ A;  2CFV A;  5EHP A;  2SHP A;  4C13 A;  2B4O A;  1Q6N A;  1G7G A;  1YN9 A;  5KA7 A;  3V0E A;  1NNY A;  4BUC A;  4ZIY A;  1J4X A;  5BZZ A;  4CVM A;  3D42 A;  4R30 A;  2PBN A;  1P3D A;  3EU0 A;  4BPC A;  2GP0 A;  1T49 A;  1XM2 A;  3PYZ A;  2I6I A;  2F6F A;  3I80 A;  3QCF A;  2F00 A;  1XXP A;  2QBS A;  3RGO A;  3S3E A;  2BZL A;  4TVV A;  3BM8 A;  4R0S A;  3V0F A;  3QKQ A;  2A3K A;  2I6M A;  2AZR A;  2C7S A;  3ZM0 A;  2F6V A;  4JNB A;  4BJO A;  1QXK A;  1AAX A;  3GXG A;  1YTS A;  1NO6 A;  1ZCK A;  3OMH A;  2AM1 A;  5J8R A;  1FQ1 A;  4OHI A;  1NWL A;  2CNI A;  2IMG A;  1PTU A;  1OHD A;  2QBQ A;  4QBE A;  1T4J A;  2H02 A;  2F70 A;  1ONY A;  5KA3 A;  3LK7 A;  1WAX A;  3O5X A;  4WU3 A;  2BGD A;  3QKP A;  4NWF A;  4WTY A;  3ZM5 A;  1LQF A;  3AWE A;  1C84 A;  5KA2 A;  1EEO A;  2VOS A;  5BZX A;  1I57 A;  5KAA A;  2CM3 A;  1L8K A;  2NT2 A;  3I7Z A;  2I6O A;  5KA4 A;  3O4U A;  1XRI A;  4NX8 A;  2UUP A;  3AWG A;  4GFV A;  4WOH A;  1A5Y A;  3S4O A;  2VEW A;  3ZMQ A;  1JF7 A;  5BX1 A;  4CVL A;  1KAV A;  3F9A A;  2NLK A;  4KI9 A;  4AZ1 A;  2PT0 A;  3D9C A;  3RGQ A;  2F71 A;  3QCK A;  1UAG A;  3SME A;  5K25 A;  2JFH A;  1BZH A;  3A5J A;  2F6T A;  3F41 A;  4RH9 A;  4UAG A;  4OHL A;  2PQ5 A;  1PTT A;  3EZZ A;  4YR8 B;  3B7O A;  2A8B A;  1PA1 A;  4RHG A;  1YGR A;  5KA8 A;  2P4D A;  1BZC A;  2GJT A;  3ZV2 A;  1PTY A;  1W78 A;  3QCH A;  4C12 A;  4BUB A;  1OEU A;  4I8N A;  2CJZ A;  3ZM2 A;  1OHE A;  3QCI A;  1ZCL A;  5AWX A;  2I3U A;  1WCH A;  1Q6M A;  2QDM A;  4JBC A;  4DGX A;  1XBO A;  1YZ4 A;  3QCE A;  1E0D A;  3QCG A;  4QUM A;  2VTE A;  4GS0 A;  2F46 A;  2WGP A;  4GE2 A;  1YGU A;  3MVN A;  2OOQ A;  2WTZ A;  1U26 A;  4GE6 A;  2YDU A;  1OEO X;  2J16 B;  5IBM A;  3S3F A;  2UUO A;  1SUG A;  1MKP A;  1OET A;  4QBW A;  1G1F A;  2UAG A;  2F6Z A;  2J16 A;  1C88 A;  4QF5 A;  3V0H A;  2QEP A;  4GRZ A;  3M4U A;  3V0J A;  1G4W R;  2B4U A;  2VEX A;  2I1Y A;  4ZN5 A;  3S3H A;  2QBP A;  3I36 A;  4QAH A;  4R0T A;  3QCZ A;  1OES A;  4PVG A;  1XXV A;  1YTN A;  2VEV A;  2Y1O A;  1NWE A;  1C83 A;  2VTD A;  2PA5 A;  1OEM X;  3V0G A;  2QDP A;  1Q6P A;  3NRS A;  1GQQ A;  2GCA A;  2Y2F A;  4OHE A;  1U25 A;  2HCM A;  3O4S A;  2H04 A;  1NZ7 A;  1W7K A;  2Y96 A;  2CMB A;  4NWG A;  2FH7 A;  1YFO A;  3U96 A;  2F6Y A;  2ZN7 A; 
#chains in the Genus database with same CATH homology
 2FJM A;  4RH5 A;  4GWF A;  3QCC A;  1M3G A;  5IBS A;  2I6J A;  2F6W A;  3O3L A;  4RI5 A;  5K9V A;  4RKK A;  1X24 A;  5KAB A;  3CWE A;  2CNE A;  5HDE A;  4HRF A;  2VEU A;  4ZRT A;  4D3P A;  4JMK A;  2B4P A;  2HC1 A;  2I75 A;  2FJN A;  1GWZ A;  3QCN A;  2CMC A;  3PS5 A;  5I6V A;  4D3R A;  4JMJ A;  3MOW A;  1Q6J A;  4QAP A;  4GFU A;  2I5X A;  1G4U S;  2HY3 A;  3MMJ A;  2B4S A;  2CNH A;  1PYN A;  2OZ5 A;  2NV5 A;  2I4G A;  1G1G A;  2B07 A;  1C87 A;  2QCT A;  5GTJ A;  2PSZ A;  3AWF A;  3RO1 A;  5LXQ B;  1I9T A;  1ONZ A;  2MBC A;  1D5R A;  3QCB A;  3NME A;  4Z6B A;  5K9W A;  2VEY A;  4RI4 A;  1QZ0 A;  3GXH A;  1U24 A;  2B49 A;  2Q47 A;  3EB1 A;  4QUN A;  2HC2 A;  4D3Q A;  5KA0 A;  1C86 A;  1GFY A;  2Q05 A;  2GWO A;  1L8G A;  1OEV A;  2BV5 A;  3O4T A;  3SR9 A;  1Q6T A;  4OHH A;  3QCD A;  3V0I A;  1YWF A;  2CM2 A;  1RPM A;  2RF6 A;  2BIJ A;  4H34 A;  4KYR A;  5KA9 A;  3QCM A;  1BZJ A;  4PYH A;  1P15 A;  3F9B A;  1C85 A;  4J51 A;  3QCJ A;  2NZ6 A;  5MMZ B;  2HNP A;  4Y14 A;  2E0T A;  4NYH A;  1LAR A;  2H4G A;  1I9S A;  4OHD A;  4YAA A;  1G7F A;  3RZ2 A;  1PH0 A;  4MBB A;  1PA9 A;  4ERC A;  4DGP A;  1R6H A;  2H03 A;  4KYQ A;  2BGE A;  3ZM3 A;  2HXP A;  2I42 A;  4NND A;  3H2X A;  1LYV A;  2I6P A;  4Y2E A;  1Q1M A;  2QDC A;  1KAK A;  3N0A A;  3EAX A;  3BLT A;  2C46 A;  1ZC0 A;  2CNG A;  3D1O A;  4H1O A;  3V0D A;  4GRY A;  1ECV A;  2B3O A;  3BRH A;  1G1H A;  2CM7 A;  1FPZ A;  3BLU A;  2I4H A;  3CM3 A;  5K23 A;  3OLR A;  3S3K A;  2G6Z A;  2PI7 A;  2NT7 A;  2HB1 A;  1WRM A;  2H4V A;  2AHS A;  2I3R A;  1T48 A;  3D1Q A;  3MOZ A;  1NL9 A;  4B04 A;  1EEN A;  3QCL A;  5KAD A;  2NTA A;  4S0G A;  2CM8 A;  4ICZ A;  5KA1 A;  2CNF A;  1FPR A;  1VHR A;  1OHC A;  2R0B A;  2CMA A;  4GE5 A;  2OC3 A;  2I4E A;  3LJ8 A;  2QBR A;  2J17 A;  2QCJ A;  1V3A A;  3A5K A;  3ZMP A;  3S4E A;  2G59 A;  2JJD A;  2P6X A;  3D44 A;  4RDD A;  2HVL A;  2M3V A;  2ZMM A;  2DXP A;  5K22 A;  5KAC A;  3ZM1 A;  1ZZW A;  1Q6S A;  2ESB A;  5M43 A;  1RXD A;  2OUD A;  2HNQ A;  2H4K A;  1YTW A;  4HJP A;  4WU2 A;  1JLN A;  3EMU A;  3F81 A;  4IKC A;  5BUG A;  3F99 A;  1PTV A;  1YPT A;  5EHR A;  3D1H A;  4ZI4 A;  1PXH A;  5K24 A;  4HJQ A;  2CFV A;  5EHP A;  2SHP A;  2B4O A;  1Q6N A;  1G7G A;  1YN9 A;  5KA7 A;  3V0E A;  1NNY A;  1J4X A;  5BZZ A;  3D42 A;  4R30 A;  2PBN A;  3EU0 A;  4BPC A;  2GP0 A;  1T49 A;  1XM2 A;  2I6I A;  2F6F A;  3I80 A;  3QCF A;  1XXP A;  2QBS A;  3RGO A;  3S3E A;  2BZL A;  4TVV A;  3BM8 A;  4R0S A;  3V0F A;  3QKQ A;  2A3K A;  2I6M A;  2AZR A;  2C7S A;  3ZM0 A;  2F6V A;  4JNB A;  4BJO A;  1QXK A;  1AAX A;  3GXG A;  1YTS A;  1NO6 A;  1ZCK A;  3OMH A;  5J8R A;  1FQ1 A;  4OHI A;  1NWL A;  2CNI A;  2IMG A;  1PTU A;  1OHD A;  2QBQ A;  4QBE A;  1T4J A;  2H02 A;  2F70 A;  1ONY A;  5KA3 A;  1WAX A;  3O5X A;  4WU3 A;  2BGD A;  3QKP A;  4NWF A;  4WTY A;  1LQF A;  3AWE A;  1C84 A;  5KA2 A;  1EEO A;  5BZX A;  1I57 A;  5KAA A;  2CM3 A;  1L8K A;  2NT2 A;  3I7Z A;  2I6O A;  5KA4 A;  3O4U A;  1XRI A;  4NX8 A;  3AWG A;  4GFV A;  4WOH A;  1A5Y A;  3S4O A;  2VEW A;  3ZMQ A;  1JF7 A;  5BX1 A;  1KAV A;  3F9A A;  2NLK A;  4KI9 A;  4AZ1 A;  2PT0 A;  3D9C A;  3RGQ A;  2F71 A;  3QCK A;  3SME A;  5K25 A;  3A5J A;  1BZH A;  3F41 A;  2F6T A;  4RH9 A;  4OHL A;  2PQ5 A;  1PTT A;  3EZZ A;  4YR8 B;  3B7O A;  2A8B A;  1PA1 A;  4RHG A;  1YGR A;  5KA8 A;  2P4D A;  1BZC A;  2GJT A;  3ZV2 A;  1PTY A;  3QCH A;  1OEU A;  4I8N A;  2CJZ A;  3ZM2 A;  1OHE A;  3QCI A;  1ZCL A;  5AWX A;  2I3U A;  1WCH A;  1Q6M A;  2QDM A;  4JBC A;  4DGX A;  1XBO A;  1YZ4 A;  3QCE A;  3QCG A;  4QUM A;  4GS0 A;  2F46 A;  2WGP A;  4GE2 A;  1YGU A;  2OOQ A;  1U26 A;  4GE6 A;  2YDU A;  1OEO X;  2J16 B;  5IBM A;  3S3F A;  1SUG A;  1MKP A;  1OET A;  4QBW A;  1G1F A;  2F6Z A;  2J16 A;  1C88 A;  3V0H A;  2QEP A;  4GRZ A;  3M4U A;  3V0J A;  1G4W R;  2B4U A;  2VEX A;  2I1Y A;  4ZN5 A;  3S3H A;  2QBP A;  3I36 A;  4QAH A;  4R0T A;  1OES A;  4PVG A;  1XXV A;  1YTN A;  2VEV A;  1NWE A;  1C83 A;  2PA5 A;  1OEM X;  3V0G A;  2QDP A;  1Q6P A;  2Y2F A;  4OHE A;  1U25 A;  2HCM A;  3O4S A;  2H04 A;  1NZ7 A;  2Y96 A;  2CMB A;  4NWG A;  2FH7 A;  1YFO A;  3U96 A;  2F6Y A;  2ZN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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