3EZZA

Crystal structure of human mkp-2
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
144
structure length
144
Chain Sequence
MGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the catalytic domain of human MKP-2 reveals a 24-mer assembly.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 4
total genus 53
structure length 144
sequence length 144
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2008-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3ezzA00
2F6FA 3D9CA 2G6ZA 2CNEA 4DGPA 2P4DA 1FPZA 5BZXA 2HB1A 2HXPA 2IMGA 2ESBA 3QCGA 3S3EA 3EU0A 5J8RA 5IBSA 4HRFA 1EEOA 3BM8A 3QCMA 3ZMPA 5M43A 3I80A 2J17A 5MMZB 3QCJA 1Q6SA 1G1FA 4KYQA 4JMKA 1T4JA 3QCKA 1WRMA 2QEPA 2VEVA 2JJDA 4BJOA 2NT7A 4NNDA 1OHDA 2I6PA 2A8BA 2H04A 1ONYA 5BZZA 1JLNA 3A5KA 2F6WA 5BX1A 1AAXA 2HC1A 5EHPA 4DGXA 3MOWA 5LXQB 1YN9A 2VEYA 1OEUA 3QCDA 5KA2A 2QCJA 3EAXA 3QCNA 1U25A 1Q6MA 1YWFA 2B3OA 2PSZA 3BLUA 1G1GA 3D1OA 1EENA 5KA1A 3O4TA 1RXDA 3MMJA 3QCLA 3BLTA 3ZM3A 3V0FA 2B49A 4KI9A 2CMCA 3QCFA 1L8KA 2CNIA 4OHEA 2ZMMA 2OZ5A 1RPMA 1ZCLA 4S0GA 1XXVA 1YTNA 4OHDA 1G4WR 2BGDA 3CM3A 1A5YA 2P6XA 3QCBA 4ZRTA 4GRYA 4H1OA 2H4VA 4JBCA 4D3PA 2F71A 5KABA 5K9WA 1OEMX 1J4XA 2RF6A 4NX8A 3V0IA 3O4UA 1C85A 5AWXA 1FQ1A 1MKPA 2NT2A 4WU2A 1I9TA 2B4PA 2QDPA 2GP0A 2VEUA 2F46A 5KADA 1QZ0A 5K23A 3F9BA 1XXPA 4OHLA 4KYRA 2B4OA 4WTYA 2Q05A 3S3HA 2CJZA 5KAAA 2CFVA 2I1YA 1ONZA 2OUDA 4J51A 3ZMQA 2J16B 4RDDA 1Q6TA 3AWGA 1JF7A 1C88A 1OEOX 2HC2A 1G7FA 2F6ZA 2CMBA 1V3AA 1KAKA 2F6TA 4ERCA 3O5XA 4GWFA 2I3UA 3QKPA 3V0EA 1D5RA 2AHSA 3S3FA 1P15A 2QBQA 1YPTA 4GS0A 2VEWA 2NV5A 1U26A 4R0TA 3RGQA 4Y2EA 4GFVA 2I6MA 2M3VA 3AWFA 3D44A 5HDEA 1KAVA 1LARA 3M4UA 2H4KA 3V0HA 1L8GA 4OHIA 5KA9A 3NMEA 5K9VA 2SHPA 3I7ZA 3A5JA 5K24A 4H34A 2ZN7A 2I4EA 3EB1A 1R6HA 1OHCA 2GWOA 3QCEA 4QBWA 5KA3A 2HNPA 4MBBA 2FH7A 3V0GA 1VHRA 3EMUA 3QKQA 3QCCA 1OETA 2NTAA 4JMJA 1OESA 3MOZA 2WGPA 3F41A 2A3KA 4YR8B 4WU3A 2B07A 3QCHA 1NWEA 5EHRA 3ZM0A 1Q6PA 3LJ8A 4GE2A 3SR9A 2I6JA 4QUMA 2CMAA 2YDUA 1YFOA 3EZZA 5K25A 2PBNA 4RH9A 1WAXA 4Z6BA 2I6IA 2QDCA 4R30A 2CNFA 2CNHA 1LYVA 2H4GA 1BZHA 3CWEA 2OC3A 1YZ4A 4GE6A 2VEXA 1OEVA 2B4UA 2I3RA 1G4US 2PI7A 4HJPA 3D1QA 3V0DA 1G7GA 1NO6A 1BZCA 4YAAA 4TVVA 1BZJA 3RGOA 4NWGA 1T48A 5KACA 2B4SA 2MBCA 2HNQA 1ZCKA 4QBEA 4RH5A 4HJQA 3B7OA 3O3LA 2C7SA 3H2XA 3V0JA 1PH0A 2I42A 3S4EA 1NNYA 5KA4A 3OLRA 1NL9A 1XRIA 1PTYA 3GXHA 2I4HA 2CM2A 1I9SA 2I5XA 1YTSA 4GFUA 3I36A 2BV5A 2J16A 1NZ7A 1QXKA 1PYNA 2GJTA 3AWEA 1GWZA 2PA5A 4ZI4A 1Q1MA 2HY3A 2I4GA 1I57A 1PXHA 4BPCA 3U96A 4QAPA 1OHEA 2DXPA 3BRHA 2BGEA 2CM3A 2HCMA 4IKCA 1Q6JA 4NYHA 1C86A 1C87A 5BUGA 3ZM1A 3PS5A 1YGRA 4AZ1A 1U24A 4I8NA 2PT0A 2E0TA 3QCIA 1GFYA 1C83A 1PTUA 4ZN5A 3S3KA 3SMEA 1YGUA 3OMHA 2F70A 4ICZA 4GE5A 4QUNA 3N0AA 4PVGA 1SUGA 4WOHA 1WCHA 1X24A 2QCTA 4QAHA 2I6OA 3GXGA 1T49A 4Y14A 2QBSA 2R0BA 2QBRA 4RI4A 5KA7A 1NWLA 2CM8A 4D3QA 2PQ5A 1PTTA 3D42A 4GRZA 1M3GA 5K22A 4D3RA 4RI5A 2H02A 2Y96A 2G59A 1Q6NA 1LQFA 1PTVA 3F99A 2F6VA 5IBMA 2QBPA 3O4SA 3D1HA 3RO1A 1YTWA 1XM2A 4RKKA 3RZ2A 4B04A 2BIJA 5GTJA 2C46A 5KA8A 3S4OA 2QDMA 4R0SA 2AZRA 4NWFA 2Q47A 2F6YA 1XBOA 2BZLA 1G1HA 2I75A 2CNGA 1ZZWA 1PA9A 2Y2FA 5KA0A 1C84A 1ZC0A 4RHGA 1PA1A 2NZ6A 3F9AA 3ZM2A 2CM7A 2OOQA 2FJMA 4JNBA 1FPRA 2HVLA 3ZV2A 2NLKA 5I6VA 1ECVA 4PYHA 2FJNA 2H03A 4OHHA 3F81A
chains in the Genus database with same CATH superfamily
2F6FA 3D9CA 1O5ZA 2G6ZA 2CNEA 4DGPA 2P4DA 1FPZA 5BZXA 2HB1A 2UUOA 2HXPA 2UAGA 2IMGA 2ESBA 3QCGA 2VTDA 3S3EA 3EU0A 5J8RA 5IBSA 4HRFA 1EEOA 3BM8A 3QCMA 3ZMPA 5M43A 3I80A 2J17A 4BUCA 5MMZB 3QCJA 1Q6SA 4QF5A 1G1FA 4KYQA 4JMKA 1T4JA 3QCKA 1WRMA 2QEPA 2VEVA 1JBWA 2JJDA 2NT7A 4NNDA 1OHDA 2I6PA 4BJOA 2GC5A 2F00A 2A8BA 2H04A 1ONYA 5BZZA 1JLNA 3A5KA 2F6WA 5BX1A 1AAXA 2HC1A 5EHPA 4DGXA 3MOWA 5LXQB 1YN9A 2JFFA 2VEYA 1OEUA 3QCDA 5KA2A 2QCJA 1P3DA 3EAXA 1GQYA 3QCNA 1U25A 1Q6MA 1YWFA 2B3OA 2PSZA 3BLUA 1G1GA 3D1OA 1EENA 5KA1A 3O4TA 1RXDA 3MMJA 3QCLA 3BLTA 3ZM3A 3V0FA 1J6UA 2B49A 4KI9A 2CMCA 3QCFA 1L8KA 4UAGA 2CNIA 4OHEA 2ZMMA 2OZ5A 1RPMA 1ZCLA 4S0GA 1XXVA 1YTNA 4OHDA 1G4WR 2BGDA 3CM3A 1A5YA 2P6XA 3QCBA 4ZRTA 4GRYA 4H1OA 2H4VA 4JBCA 4D3PA 2F71A 5KABA 1UAGA 1W7KA 5K9WA 1OEMX 3N2AA 1J4XA 2RF6A 4NX8A 3V0IA 3O4UA 1C85A 5AWXA 1FQ1A 3HN7A 1MKPA 2VOSA 2NT2A 4WU2A 1I9TA 2B4PA 2QDPA 2GP0A 2VEUA 2F46A 5KADA 1QZ0A 5K23A 3F9BA 1XXPA 2JFHA 4OHLA 4KYRA 2B4OA 4WTYA 2Q05A 3S3HA 2CJZA 5KAAA 2VORA 2CFVA 2I1YA 1ONZA 2OUDA 4J51A 3ZMQA 2J16B 4RDDA 1Q6TA 3AWGA 1JF7A 2GCBA 1OEOX 1C88A 2HC2A 1G7FA 2F6ZA 2X5OA 2CMBA 1V3AA 1KAKA 2F6TA 4ERCA 3O5XA 4GWFA 2I3UA 3QKPA 3V0EA 1D5RA 2AHSA 3S3FA 1P15A 2QBQA 1YPTA 2AM2A 4GS0A 2VEWA 1GG4A 2NV5A 1U26A 4R0TA 3RGQA 4Y2EA 4GFVA 2I6MA 2M3VA 3AWFA 3D44A 5HDEA 1KAVA 1E8CA 4ZIYA 1LARA 3M4UA 1FGSA 2H4KA 3V0HA 1L8GA 4OHIA 5KA9A 3NMEA 5K9VA 4C13A 2SHPA 3I7ZA 3A5JA 3PYZA 5K24A 4H34A 2ZN7A 2I4EA 3EB1A 1R6HA 4C12A 1OHCA 2GWOA 3QCEA 4QBWA 5KA3A 2HNPA 4MBBA 2FH7A 3V0GA 3NRSA 1VHRA 4HV4A 3EMUA 3QKQA 3QCCA 1OETA 2NTAA 4JMJA 1OESA 5A5EA 3MOZA 2WGPA 3F41A 2A3KA 4YR8B 4WU3A 2B07A 3QCHA 1NWEA 5EHRA 1W78A 2JFGA 3ZM0A 1Q6PA 3LJ8A 4GE2A 3ZM5A 2WTZA 2GCAA 2Y1OA 3SR9A 2I6JA 4QUMA 2CMAA 2YDUA 1YFOA 2XPCA 3EZZA 5K25A 2PBNA 4RH9A 1WAXA 4Z6BA 2I6IA 2QDCA 4R30A 2CNFA 2CNHA 1LYVA 2AM1A 1BZHA 2H4GA 3CWEA 2OC3A 1YZ4A 4GE6A 2VEXA 1OEVA 2B4UA 2I3RA 1P31A 1G4US 2PI7A 4HJPA 3D1QA 3V0DA 1G7GA 2Y68A 1NO6A 1BZCA 4CVMA 4YAAA 4TVVA 4CVLA 1BZJA 3RGOA 4NWGA 1T48A 2UUPA 5KACA 2B4SA 2MBCA 2HNQA 1ZCKA 4QBEA 4RH5A 3ZM6A 4HJQA 3B7OA 1GQQA 3O3LA 2C7SA 4CVKA 3H2XA 4BUBA 3V0JA 1PH0A 2I42A 3S4EA 1NNYA 5KA4A 3OLRA 1NL9A 1XRIA 1PTYA 3GXHA 2I4HA 2CM2A 1I9SA 3UAGA 2I5XA 1YTSA 4GFUA 3I36A 2BV5A 2J16A 1NZ7A 1QXKA 1JBVA 1PYNA 2GJTA 3AWEA 1GWZA 2PA5A 4ZI4A 1Q1MA 2HY3A 2I4GA 1I57A 1PXHA 4BPCA 3U96A 4QAPA 4QDIA 1OHEA 2DXPA 3BRHA 2BGEA 2CM3A 2HCMA 4IKCA 1Q6JA 4NYHA 2VTEA 1C86A 1C87A 5BUGA 3ZM1A 5A5FA 3PS5A 1YGRA 4AZ1A 1U24A 4I8NA 2PT0A 2E0TA 3QCIA 1GFYA 1C83A 2WJPA 1PTUA 4ZN5A 3S3KA 3SMEA 1YGUA 3OMHA 2F70A 4ICZA 4GE5A 4QUNA 3N0AA 4PVGA 1SUGA 4WOHA 1WCHA 1E0DA 1X24A 2QCTA 2I6OA 3GXGA 4QAHA 1T49A 4Y14A 2QBSA 2R0BA 2QBRA 4RI4A 5KA7A 1NWLA 2CM8A 4D3QA 2PQ5A 1PTTA 3D42A 4GRZA 1M3GA 5K22A 4D3RA 2XJAA 4RI5A 2H02A 2Y96A 2G59A 1Q6NA 1LQFA 1PTVA 2GC6A 3F99A 2F6VA 5IBMA 2QBPA 3O4SA 3MVNA 3D1HA 3RO1A 1YTWA 1EEHA 1XM2A 4RKKA 3RZ2A 4B04A 2Y66A 2BIJA 5GTJA 2C46A 5KA8A 3S4OA 2QDMA 4R0SA 2AZRA 4NWFA 2Q47A 3QCZA 3ZL8A 2F6YA 1XBOA 2BZLA 1G1HA 2I75A 2CNGA 1ZZWA 1PA9A 2Y2FA 5KA0A 1C84A 1ZC0A 4RHGA 1PA1A 2NZ6A 3F9AA 3ZM2A 2CM7A 2OOQA 2FJMA 4JNBA 1FPRA 2HVLA 3ZV2A 2Y67A 2NLKA 5I6VA 1ECVA 4PYHA 2FJNA 2H03A 3LK7A 4OHHA 3F81A
chains in the Genus database with same CATH topology
2F6FA 3D9CA 2G6ZA 2CNEA 4DGPA 2P4DA 1FPZA 5BZXA 2HB1A 2HXPA 2IMGA 2ESBA 3QCGA 3S3EA 3EU0A 5J8RA 5IBSA 4HRFA 1EEOA 3BM8A 3QCMA 3ZMPA 5M43A 3I80A 2J17A 5MMZB 3QCJA 1Q6SA 1G1FA 4KYQA 4JMKA 1T4JA 3QCKA 1WRMA 2QEPA 2VEVA 2JJDA 4BJOA 2NT7A 4NNDA 1OHDA 2I6PA 2A8BA 2H04A 1ONYA 5BZZA 1JLNA 3A5KA 2F6WA 5BX1A 1AAXA 2HC1A 5EHPA 4DGXA 3MOWA 5LXQB 1YN9A 2VEYA 1OEUA 3QCDA 5KA2A 2QCJA 3EAXA 3QCNA 1U25A 1Q6MA 1YWFA 2B3OA 2PSZA 3BLUA 1G1GA 3D1OA 1EENA 5KA1A 3O4TA 1RXDA 3MMJA 3QCLA 3BLTA 3ZM3A 3V0FA 2B49A 4KI9A 2CMCA 3QCFA 1L8KA 2CNIA 4OHEA 2ZMMA 2OZ5A 1RPMA 1ZCLA 4S0GA 1XXVA 1YTNA 4OHDA 1G4WR 2BGDA 3CM3A 1A5YA 2P6XA 3QCBA 4ZRTA 4GRYA 4H1OA 2H4VA 4JBCA 4D3PA 2F71A 5KABA 5K9WA 1OEMX 1J4XA 2RF6A 4NX8A 3V0IA 3O4UA 1C85A 5AWXA 1FQ1A 1MKPA 2NT2A 4WU2A 1I9TA 2B4PA 2QDPA 2GP0A 2VEUA 2F46A 5KADA 1QZ0A 5K23A 3F9BA 1XXPA 4OHLA 4KYRA 2B4OA 4WTYA 2Q05A 3S3HA 2CJZA 5KAAA 2CFVA 2I1YA 1ONZA 2OUDA 4J51A 3ZMQA 2J16B 4RDDA 1Q6TA 3AWGA 1JF7A 1C88A 1OEOX 2HC2A 1G7FA 2F6ZA 2CMBA 1V3AA 1KAKA 2F6TA 4ERCA 3O5XA 4GWFA 2I3UA 3QKPA 3V0EA 1D5RA 2AHSA 3S3FA 1P15A 2QBQA 1YPTA 4GS0A 2VEWA 2NV5A 1U26A 4R0TA 3RGQA 4Y2EA 4GFVA 2I6MA 2M3VA 3AWFA 3D44A 5HDEA 1KAVA 1LARA 3M4UA 2H4KA 3V0HA 1L8GA 4OHIA 5KA9A 3NMEA 5K9VA 2SHPA 3I7ZA 3A5JA 5K24A 4H34A 2ZN7A 2I4EA 3EB1A 1R6HA 1OHCA 2GWOA 3QCEA 4QBWA 5KA3A 2HNPA 4MBBA 2FH7A 3V0GA 1VHRA 3EMUA 3QKQA 3QCCA 1OETA 2NTAA 4JMJA 1OESA 3MOZA 2WGPA 3F41A 2A3KA 4YR8B 4WU3A 2B07A 3QCHA 1NWEA 5EHRA 3ZM0A 1Q6PA 3LJ8A 4GE2A 3SR9A 2I6JA 4QUMA 2CMAA 2YDUA 1YFOA 3EZZA 5K25A 2PBNA 4RH9A 1WAXA 4Z6BA 2I6IA 2QDCA 4R30A 2CNFA 2CNHA 1LYVA 2H4GA 1BZHA 3CWEA 2OC3A 1YZ4A 4GE6A 2VEXA 1OEVA 2B4UA 2I3RA 1G4US 2PI7A 4HJPA 3D1QA 3V0DA 1G7GA 1NO6A 1BZCA 4YAAA 4TVVA 1BZJA 3RGOA 4NWGA 1T48A 5KACA 2B4SA 2MBCA 2HNQA 1ZCKA 4QBEA 4RH5A 4HJQA 3B7OA 3O3LA 2C7SA 3H2XA 3V0JA 1PH0A 2I42A 3S4EA 1NNYA 5KA4A 3OLRA 1NL9A 1XRIA 1PTYA 3GXHA 2I4HA 2CM2A 1I9SA 2I5XA 1YTSA 4GFUA 3I36A 2BV5A 2J16A 1NZ7A 1QXKA 1PYNA 2GJTA 3AWEA 1GWZA 2PA5A 4ZI4A 1Q1MA 2HY3A 2I4GA 1I57A 1PXHA 4BPCA 3U96A 4QAPA 1OHEA 2DXPA 3BRHA 2BGEA 2CM3A 2HCMA 4IKCA 1Q6JA 4NYHA 1C86A 1C87A 5BUGA 3ZM1A 3PS5A 1YGRA 4AZ1A 1U24A 4I8NA 2PT0A 2E0TA 3QCIA 1GFYA 1C83A 1PTUA 4ZN5A 3S3KA 3SMEA 1YGUA 3OMHA 2F70A 4ICZA 4GE5A 4QUNA 3N0AA 4PVGA 1SUGA 4WOHA 1WCHA 1X24A 2QCTA 4QAHA 2I6OA 3GXGA 1T49A 4Y14A 2QBSA 2R0BA 2QBRA 4RI4A 5KA7A 1NWLA 2CM8A 4D3QA 2PQ5A 1PTTA 3D42A 4GRZA 1M3GA 5K22A 4D3RA 4RI5A 2H02A 2Y96A 2G59A 1Q6NA 1LQFA 1PTVA 3F99A 2F6VA 5IBMA 2QBPA 3O4SA 3D1HA 3RO1A 1YTWA 1XM2A 4RKKA 3RZ2A 4B04A 2BIJA 5GTJA 2C46A 5KA8A 3S4OA 2QDMA 4R0SA 2AZRA 4NWFA 2Q47A 2F6YA 1XBOA 2BZLA 1G1HA 2I75A 2CNGA 1ZZWA 1PA9A 2Y2FA 5KA0A 1C84A 1ZC0A 4RHGA 1PA1A 2NZ6A 3F9AA 3ZM2A 2CM7A 2OOQA 2FJMA 4JNBA 1FPRA 2HVLA 3ZV2A 2NLKA 5I6VA 1ECVA 4PYHA 2FJNA 2H03A 4OHHA 3F81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F6F A;  3D9C A;  2G6Z A;  2CNE A;  4DGP A;  2P4D A;  1FPZ A;  5BZX A;  2HB1 A;  2HXP A;  2IMG A;  2ESB A;  3QCG A;  3S3E A;  3EU0 A;  5J8R A;  5IBS A;  4HRF A;  1EEO A;  3BM8 A;  3QCM A;  3ZMP A;  5M43 A;  3I80 A;  2J17 A;  5MMZ B;  3QCJ A;  1Q6S A;  1G1F A;  4KYQ A;  4JMK A;  1T4J A;  3QCK A;  1WRM A;  2QEP A;  2VEV A;  2JJD A;  4BJO A;  2NT7 A;  4NND A;  1OHD A;  2I6P A;  2A8B A;  2H04 A;  1ONY A;  5BZZ A;  1JLN A;  3A5K A;  2F6W A;  5BX1 A;  1AAX A;  2HC1 A;  5EHP A;  4DGX A;  3MOW A;  5LXQ B;  1YN9 A;  2VEY A;  1OEU A;  3QCD A;  5KA2 A;  2QCJ A;  3EAX A;  3QCN A;  1U25 A;  1Q6M A;  1YWF A;  2B3O A;  2PSZ A;  3BLU A;  1G1G A;  3D1O A;  1EEN A;  5KA1 A;  3O4T A;  1RXD A;  3MMJ A;  3QCL A;  3BLT A;  3ZM3 A;  3V0F A;  2B49 A;  4KI9 A;  2CMC A;  3QCF A;  1L8K A;  2CNI A;  4OHE A;  2ZMM A;  2OZ5 A;  1RPM A;  1ZCL A;  4S0G A;  1XXV A;  1YTN A;  4OHD A;  1G4W R;  2BGD A;  3CM3 A;  1A5Y A;  2P6X A;  3QCB A;  4ZRT A;  4GRY A;  4H1O A;  2H4V A;  4JBC A;  4D3P A;  2F71 A;  5KAB A;  5K9W A;  1OEM X;  1J4X A;  2RF6 A;  4NX8 A;  3V0I A;  3O4U A;  1C85 A;  5AWX A;  1FQ1 A;  1MKP A;  2NT2 A;  4WU2 A;  1I9T A;  2B4P A;  2QDP A;  2GP0 A;  2VEU A;  2F46 A;  5KAD A;  1QZ0 A;  5K23 A;  3F9B A;  1XXP A;  4OHL A;  4KYR A;  2B4O A;  4WTY A;  2Q05 A;  3S3H A;  2CJZ A;  5KAA A;  2CFV A;  2I1Y A;  1ONZ A;  2OUD A;  4J51 A;  3ZMQ A;  2J16 B;  4RDD A;  1Q6T A;  3AWG A;  1JF7 A;  1C88 A;  1OEO X;  2HC2 A;  1G7F A;  2F6Z A;  2CMB A;  1V3A A;  1KAK A;  2F6T A;  4ERC A;  3O5X A;  4GWF A;  2I3U A;  3QKP A;  3V0E A;  1D5R A;  2AHS A;  3S3F A;  1P15 A;  2QBQ A;  1YPT A;  4GS0 A;  2VEW A;  2NV5 A;  1U26 A;  4R0T A;  3RGQ A;  4Y2E A;  4GFV A;  2I6M A;  2M3V A;  3AWF A;  3D44 A;  5HDE A;  1KAV A;  1LAR A;  3M4U A;  2H4K A;  3V0H A;  1L8G A;  4OHI A;  5KA9 A;  3NME A;  5K9V A;  2SHP A;  3I7Z A;  3A5J A;  5K24 A;  4H34 A;  2ZN7 A;  2I4E A;  3EB1 A;  1R6H A;  1OHC A;  2GWO A;  3QCE A;  4QBW A;  5KA3 A;  2HNP A;  4MBB A;  2FH7 A;  3V0G A;  1VHR A;  3EMU A;  3QKQ A;  3QCC A;  1OET A;  2NTA A;  4JMJ A;  1OES A;  3MOZ A;  2WGP A;  3F41 A;  2A3K A;  4YR8 B;  4WU3 A;  2B07 A;  3QCH A;  1NWE A;  5EHR A;  3ZM0 A;  1Q6P A;  3LJ8 A;  4GE2 A;  3SR9 A;  2I6J A;  4QUM A;  2CMA A;  2YDU A;  1YFO A;  3EZZ A;  5K25 A;  2PBN A;  4RH9 A;  1WAX A;  4Z6B A;  2I6I A;  2QDC A;  4R30 A;  2CNF A;  2CNH A;  1LYV A;  2H4G A;  1BZH A;  3CWE A;  2OC3 A;  1YZ4 A;  4GE6 A;  2VEX A;  1OEV A;  2B4U A;  2I3R A;  1G4U S;  2PI7 A;  4HJP A;  3D1Q A;  3V0D A;  1G7G A;  1NO6 A;  1BZC A;  4YAA A;  4TVV A;  1BZJ A;  3RGO A;  4NWG A;  1T48 A;  5KAC A;  2B4S A;  2MBC A;  2HNQ A;  1ZCK A;  4QBE A;  4RH5 A;  4HJQ A;  3B7O A;  3O3L A;  2C7S A;  3H2X A;  3V0J A;  1PH0 A;  2I42 A;  3S4E A;  1NNY A;  5KA4 A;  3OLR A;  1NL9 A;  1XRI A;  1PTY A;  3GXH A;  2I4H A;  2CM2 A;  1I9S A;  2I5X A;  1YTS A;  4GFU A;  3I36 A;  2BV5 A;  2J16 A;  1NZ7 A;  1QXK A;  1PYN A;  2GJT A;  3AWE A;  1GWZ A;  2PA5 A;  4ZI4 A;  1Q1M A;  2HY3 A;  2I4G A;  1I57 A;  1PXH A;  4BPC A;  3U96 A;  4QAP A;  1OHE A;  2DXP A;  3BRH A;  2BGE A;  2CM3 A;  2HCM A;  4IKC A;  1Q6J A;  4NYH A;  1C86 A;  1C87 A;  5BUG A;  3ZM1 A;  3PS5 A;  1YGR A;  4AZ1 A;  1U24 A;  4I8N A;  2PT0 A;  2E0T A;  3QCI A;  1GFY A;  1C83 A;  1PTU A;  4ZN5 A;  3S3K A;  3SME A;  1YGU A;  3OMH A;  2F70 A;  4ICZ A;  4GE5 A;  4QUN A;  3N0A A;  4PVG A;  1SUG A;  4WOH A;  1WCH A;  1X24 A;  2QCT A;  4QAH A;  2I6O A;  3GXG A;  1T49 A;  4Y14 A;  2QBS A;  2R0B A;  2QBR A;  4RI4 A;  5KA7 A;  1NWL A;  2CM8 A;  4D3Q A;  2PQ5 A;  1PTT A;  3D42 A;  4GRZ A;  1M3G A;  5K22 A;  4D3R A;  4RI5 A;  2H02 A;  2Y96 A;  2G59 A;  1Q6N A;  1LQF A;  1PTV A;  3F99 A;  2F6V A;  5IBM A;  2QBP A;  3O4S A;  3D1H A;  3RO1 A;  1YTW A;  1XM2 A;  4RKK A;  3RZ2 A;  4B04 A;  2BIJ A;  5GTJ A;  2C46 A;  5KA8 A;  3S4O A;  2QDM A;  4R0S A;  2AZR A;  4NWF A;  2Q47 A;  2F6Y A;  1XBO A;  2BZL A;  1G1H A;  2I75 A;  2CNG A;  1ZZW A;  1PA9 A;  2Y2F A;  5KA0 A;  1C84 A;  1ZC0 A;  4RHG A;  1PA1 A;  2NZ6 A;  3F9A A;  3ZM2 A;  2CM7 A;  2OOQ A;  2FJM A;  4JNB A;  1FPR A;  2HVL A;  3ZV2 A;  2NLK A;  5I6V A;  1ECV A;  4PYH A;  2FJN A;  2H03 A;  4OHH A;  3F81 A; 
#chains in the Genus database with same CATH topology
 2F6F A;  3D9C A;  1O5Z A;  2G6Z A;  2CNE A;  4DGP A;  2P4D A;  1FPZ A;  5BZX A;  2HB1 A;  2UUO A;  2HXP A;  2UAG A;  2IMG A;  2ESB A;  3QCG A;  2VTD A;  3S3E A;  3EU0 A;  5J8R A;  5IBS A;  4HRF A;  1EEO A;  3BM8 A;  3QCM A;  3ZMP A;  5M43 A;  3I80 A;  2J17 A;  4BUC A;  5MMZ B;  3QCJ A;  1Q6S A;  4QF5 A;  1G1F A;  4KYQ A;  4JMK A;  1T4J A;  3QCK A;  1WRM A;  2QEP A;  2VEV A;  1JBW A;  2JJD A;  2NT7 A;  4NND A;  1OHD A;  2I6P A;  4BJO A;  2GC5 A;  2F00 A;  2A8B A;  2H04 A;  1ONY A;  5BZZ A;  1JLN A;  3A5K A;  2F6W A;  5BX1 A;  1AAX A;  2HC1 A;  5EHP A;  4DGX A;  3MOW A;  5LXQ B;  1YN9 A;  2JFF A;  2VEY A;  1OEU A;  3QCD A;  5KA2 A;  2QCJ A;  1P3D A;  3EAX A;  1GQY A;  3QCN A;  1U25 A;  1Q6M A;  1YWF A;  2B3O A;  2PSZ A;  3BLU A;  1G1G A;  3D1O A;  1EEN A;  5KA1 A;  3O4T A;  1RXD A;  3MMJ A;  3QCL A;  3BLT A;  3ZM3 A;  3V0F A;  1J6U A;  2B49 A;  4KI9 A;  2CMC A;  3QCF A;  1L8K A;  4UAG A;  2CNI A;  4OHE A;  2ZMM A;  2OZ5 A;  1RPM A;  1ZCL A;  4S0G A;  1XXV A;  1YTN A;  4OHD A;  1G4W R;  2BGD A;  3CM3 A;  1A5Y A;  2P6X A;  3QCB A;  4ZRT A;  4GRY A;  4H1O A;  2H4V A;  4JBC A;  4D3P A;  2F71 A;  5KAB A;  1UAG A;  1W7K A;  5K9W A;  1OEM X;  3N2A A;  1J4X A;  2RF6 A;  4NX8 A;  3V0I A;  3O4U A;  1C85 A;  5AWX A;  1FQ1 A;  3HN7 A;  1MKP A;  2VOS A;  2NT2 A;  4WU2 A;  1I9T A;  2B4P A;  2QDP A;  2GP0 A;  2VEU A;  2F46 A;  5KAD A;  1QZ0 A;  5K23 A;  3F9B A;  1XXP A;  2JFH A;  4OHL A;  4KYR A;  2B4O A;  4WTY A;  2Q05 A;  3S3H A;  2CJZ A;  5KAA A;  2VOR A;  2CFV A;  2I1Y A;  1ONZ A;  2OUD A;  4J51 A;  3ZMQ A;  2J16 B;  4RDD A;  1Q6T A;  3AWG A;  1JF7 A;  2GCB A;  1OEO X;  1C88 A;  2HC2 A;  1G7F A;  2F6Z A;  2X5O A;  2CMB A;  1V3A A;  1KAK A;  2F6T A;  4ERC A;  3O5X A;  4GWF A;  2I3U A;  3QKP A;  3V0E A;  1D5R A;  2AHS A;  3S3F A;  1P15 A;  2QBQ A;  1YPT A;  2AM2 A;  4GS0 A;  2VEW A;  1GG4 A;  2NV5 A;  1U26 A;  4R0T A;  3RGQ A;  4Y2E A;  4GFV A;  2I6M A;  2M3V A;  3AWF A;  3D44 A;  5HDE A;  1KAV A;  1E8C A;  4ZIY A;  1LAR A;  3M4U A;  1FGS A;  2H4K A;  3V0H A;  1L8G A;  4OHI A;  5KA9 A;  3NME A;  5K9V A;  4C13 A;  2SHP A;  3I7Z A;  3A5J A;  3PYZ A;  5K24 A;  4H34 A;  2ZN7 A;  2I4E A;  3EB1 A;  1R6H A;  4C12 A;  1OHC A;  2GWO A;  3QCE A;  4QBW A;  5KA3 A;  2HNP A;  4MBB A;  2FH7 A;  3V0G A;  3NRS A;  1VHR A;  4HV4 A;  3EMU A;  3QKQ A;  3QCC A;  1OET A;  2NTA A;  4JMJ A;  1OES A;  5A5E A;  3MOZ A;  2WGP A;  3F41 A;  2A3K A;  4YR8 B;  4WU3 A;  2B07 A;  3QCH A;  1NWE A;  5EHR A;  1W78 A;  2JFG A;  3ZM0 A;  1Q6P A;  3LJ8 A;  4GE2 A;  3ZM5 A;  2WTZ A;  2GCA A;  2Y1O A;  3SR9 A;  2I6J A;  4QUM A;  2CMA A;  2YDU A;  1YFO A;  2XPC A;  3EZZ A;  5K25 A;  2PBN A;  4RH9 A;  1WAX A;  4Z6B A;  2I6I A;  2QDC A;  4R30 A;  2CNF A;  2CNH A;  1LYV A;  2AM1 A;  1BZH A;  2H4G A;  3CWE A;  2OC3 A;  1YZ4 A;  4GE6 A;  2VEX A;  1OEV A;  2B4U A;  2I3R A;  1P31 A;  1G4U S;  2PI7 A;  4HJP A;  3D1Q A;  3V0D A;  1G7G A;  2Y68 A;  1NO6 A;  1BZC A;  4CVM A;  4YAA A;  4TVV A;  4CVL A;  1BZJ A;  3RGO A;  4NWG A;  1T48 A;  2UUP A;  5KAC A;  2B4S A;  2MBC A;  2HNQ A;  1ZCK A;  4QBE A;  4RH5 A;  3ZM6 A;  4HJQ A;  3B7O A;  1GQQ A;  3O3L A;  2C7S A;  4CVK A;  3H2X A;  4BUB A;  3V0J A;  1PH0 A;  2I42 A;  3S4E A;  1NNY A;  5KA4 A;  3OLR A;  1NL9 A;  1XRI A;  1PTY A;  3GXH A;  2I4H A;  2CM2 A;  1I9S A;  3UAG A;  2I5X A;  1YTS A;  4GFU A;  3I36 A;  2BV5 A;  2J16 A;  1NZ7 A;  1QXK A;  1JBV A;  1PYN A;  2GJT A;  3AWE A;  1GWZ A;  2PA5 A;  4ZI4 A;  1Q1M A;  2HY3 A;  2I4G A;  1I57 A;  1PXH A;  4BPC A;  3U96 A;  4QAP A;  4QDI A;  1OHE A;  2DXP A;  3BRH A;  2BGE A;  2CM3 A;  2HCM A;  4IKC A;  1Q6J A;  4NYH A;  2VTE A;  1C86 A;  1C87 A;  5BUG A;  3ZM1 A;  5A5F A;  3PS5 A;  1YGR A;  4AZ1 A;  1U24 A;  4I8N A;  2PT0 A;  2E0T A;  3QCI A;  1GFY A;  1C83 A;  2WJP A;  1PTU A;  4ZN5 A;  3S3K A;  3SME A;  1YGU A;  3OMH A;  2F70 A;  4ICZ A;  4GE5 A;  4QUN A;  3N0A A;  4PVG A;  1SUG A;  4WOH A;  1WCH A;  1E0D A;  1X24 A;  2QCT A;  2I6O A;  3GXG A;  4QAH A;  1T49 A;  4Y14 A;  2QBS A;  2R0B A;  2QBR A;  4RI4 A;  5KA7 A;  1NWL A;  2CM8 A;  4D3Q A;  2PQ5 A;  1PTT A;  3D42 A;  4GRZ A;  1M3G A;  5K22 A;  4D3R A;  2XJA A;  4RI5 A;  2H02 A;  2Y96 A;  2G59 A;  1Q6N A;  1LQF A;  1PTV A;  2GC6 A;  3F99 A;  2F6V A;  5IBM A;  2QBP A;  3O4S A;  3MVN A;  3D1H A;  3RO1 A;  1YTW A;  1EEH A;  1XM2 A;  4RKK A;  3RZ2 A;  4B04 A;  2Y66 A;  2BIJ A;  5GTJ A;  2C46 A;  5KA8 A;  3S4O A;  2QDM A;  4R0S A;  2AZR A;  4NWF A;  2Q47 A;  3QCZ A;  3ZL8 A;  2F6Y A;  1XBO A;  2BZL A;  1G1H A;  2I75 A;  2CNG A;  1ZZW A;  1PA9 A;  2Y2F A;  5KA0 A;  1C84 A;  1ZC0 A;  4RHG A;  1PA1 A;  2NZ6 A;  3F9A A;  3ZM2 A;  2CM7 A;  2OOQ A;  2FJM A;  4JNB A;  1FPR A;  2HVL A;  3ZV2 A;  2Y67 A;  2NLK A;  5I6V A;  1ECV A;  4PYH A;  2FJN A;  2H03 A;  3LK7 A;  4OHH A;  3F81 A; 
#chains in the Genus database with same CATH homology
 2F6F A;  3D9C A;  2G6Z A;  2CNE A;  4DGP A;  2P4D A;  1FPZ A;  5BZX A;  2HB1 A;  2HXP A;  2IMG A;  2ESB A;  3QCG A;  3S3E A;  3EU0 A;  5J8R A;  5IBS A;  4HRF A;  1EEO A;  3BM8 A;  3QCM A;  3ZMP A;  5M43 A;  3I80 A;  2J17 A;  5MMZ B;  3QCJ A;  1Q6S A;  1G1F A;  4KYQ A;  4JMK A;  1T4J A;  3QCK A;  1WRM A;  2QEP A;  2VEV A;  2JJD A;  4BJO A;  2NT7 A;  4NND A;  1OHD A;  2I6P A;  2A8B A;  2H04 A;  1ONY A;  5BZZ A;  1JLN A;  3A5K A;  2F6W A;  5BX1 A;  1AAX A;  2HC1 A;  5EHP A;  4DGX A;  3MOW A;  5LXQ B;  1YN9 A;  2VEY A;  1OEU A;  3QCD A;  5KA2 A;  2QCJ A;  3EAX A;  3QCN A;  1U25 A;  1Q6M A;  1YWF A;  2B3O A;  2PSZ A;  3BLU A;  1G1G A;  3D1O A;  1EEN A;  5KA1 A;  3O4T A;  1RXD A;  3MMJ A;  3QCL A;  3BLT A;  3ZM3 A;  3V0F A;  2B49 A;  4KI9 A;  2CMC A;  3QCF A;  1L8K A;  2CNI A;  4OHE A;  2ZMM A;  2OZ5 A;  1RPM A;  1ZCL A;  4S0G A;  1XXV A;  1YTN A;  4OHD A;  1G4W R;  2BGD A;  3CM3 A;  1A5Y A;  2P6X A;  3QCB A;  4ZRT A;  4GRY A;  4H1O A;  2H4V A;  4JBC A;  4D3P A;  2F71 A;  5KAB A;  5K9W A;  1OEM X;  1J4X A;  2RF6 A;  4NX8 A;  3V0I A;  3O4U A;  1C85 A;  5AWX A;  1FQ1 A;  1MKP A;  2NT2 A;  4WU2 A;  1I9T A;  2B4P A;  2QDP A;  2GP0 A;  2VEU A;  2F46 A;  5KAD A;  1QZ0 A;  5K23 A;  3F9B A;  1XXP A;  4OHL A;  4KYR A;  2B4O A;  4WTY A;  2Q05 A;  3S3H A;  2CJZ A;  5KAA A;  2CFV A;  2I1Y A;  1ONZ A;  2OUD A;  4J51 A;  3ZMQ A;  2J16 B;  4RDD A;  1Q6T A;  3AWG A;  1JF7 A;  1C88 A;  1OEO X;  2HC2 A;  1G7F A;  2F6Z A;  2CMB A;  1V3A A;  1KAK A;  2F6T A;  4ERC A;  3O5X A;  4GWF A;  2I3U A;  3QKP A;  3V0E A;  1D5R A;  2AHS A;  3S3F A;  1P15 A;  2QBQ A;  1YPT A;  4GS0 A;  2VEW A;  2NV5 A;  1U26 A;  4R0T A;  3RGQ A;  4Y2E A;  4GFV A;  2I6M A;  2M3V A;  3AWF A;  3D44 A;  5HDE A;  1KAV A;  1LAR A;  3M4U A;  2H4K A;  3V0H A;  1L8G A;  4OHI A;  5KA9 A;  3NME A;  5K9V A;  2SHP A;  3I7Z A;  3A5J A;  5K24 A;  4H34 A;  2ZN7 A;  2I4E A;  3EB1 A;  1R6H A;  1OHC A;  2GWO A;  3QCE A;  4QBW A;  5KA3 A;  2HNP A;  4MBB A;  2FH7 A;  3V0G A;  1VHR A;  3EMU A;  3QKQ A;  3QCC A;  1OET A;  2NTA A;  4JMJ A;  1OES A;  3MOZ A;  2WGP A;  3F41 A;  2A3K A;  4YR8 B;  4WU3 A;  2B07 A;  3QCH A;  1NWE A;  5EHR A;  3ZM0 A;  1Q6P A;  3LJ8 A;  4GE2 A;  3SR9 A;  2I6J A;  4QUM A;  2CMA A;  2YDU A;  1YFO A;  3EZZ A;  5K25 A;  2PBN A;  4RH9 A;  1WAX A;  4Z6B A;  2I6I A;  2QDC A;  4R30 A;  2CNF A;  2CNH A;  1LYV A;  2H4G A;  1BZH A;  3CWE A;  2OC3 A;  1YZ4 A;  4GE6 A;  2VEX A;  1OEV A;  2B4U A;  2I3R A;  1G4U S;  2PI7 A;  4HJP A;  3D1Q A;  3V0D A;  1G7G A;  1NO6 A;  1BZC A;  4YAA A;  4TVV A;  1BZJ A;  3RGO A;  4NWG A;  1T48 A;  5KAC A;  2B4S A;  2MBC A;  2HNQ A;  1ZCK A;  4QBE A;  4RH5 A;  4HJQ A;  3B7O A;  3O3L A;  2C7S A;  3H2X A;  3V0J A;  1PH0 A;  2I42 A;  3S4E A;  1NNY A;  5KA4 A;  3OLR A;  1NL9 A;  1XRI A;  1PTY A;  3GXH A;  2I4H A;  2CM2 A;  1I9S A;  2I5X A;  1YTS A;  4GFU A;  3I36 A;  2BV5 A;  2J16 A;  1NZ7 A;  1QXK A;  1PYN A;  2GJT A;  3AWE A;  1GWZ A;  2PA5 A;  4ZI4 A;  1Q1M A;  2HY3 A;  2I4G A;  1I57 A;  1PXH A;  4BPC A;  3U96 A;  4QAP A;  1OHE A;  2DXP A;  3BRH A;  2BGE A;  2CM3 A;  2HCM A;  4IKC A;  1Q6J A;  4NYH A;  1C86 A;  1C87 A;  5BUG A;  3ZM1 A;  3PS5 A;  1YGR A;  4AZ1 A;  1U24 A;  4I8N A;  2PT0 A;  2E0T A;  3QCI A;  1GFY A;  1C83 A;  1PTU A;  4ZN5 A;  3S3K A;  3SME A;  1YGU A;  3OMH A;  2F70 A;  4ICZ A;  4GE5 A;  4QUN A;  3N0A A;  4PVG A;  1SUG A;  4WOH A;  1WCH A;  1X24 A;  2QCT A;  4QAH A;  2I6O A;  3GXG A;  1T49 A;  4Y14 A;  2QBS A;  2R0B A;  2QBR A;  4RI4 A;  5KA7 A;  1NWL A;  2CM8 A;  4D3Q A;  2PQ5 A;  1PTT A;  3D42 A;  4GRZ A;  1M3G A;  5K22 A;  4D3R A;  4RI5 A;  2H02 A;  2Y96 A;  2G59 A;  1Q6N A;  1LQF A;  1PTV A;  3F99 A;  2F6V A;  5IBM A;  2QBP A;  3O4S A;  3D1H A;  3RO1 A;  1YTW A;  1XM2 A;  4RKK A;  3RZ2 A;  4B04 A;  2BIJ A;  5GTJ A;  2C46 A;  5KA8 A;  3S4O A;  2QDM A;  4R0S A;  2AZR A;  4NWF A;  2Q47 A;  2F6Y A;  1XBO A;  2BZL A;  1G1H A;  2I75 A;  2CNG A;  1ZZW A;  1PA9 A;  2Y2F A;  5KA0 A;  1C84 A;  1ZC0 A;  4RHG A;  1PA1 A;  2NZ6 A;  3F9A A;  3ZM2 A;  2CM7 A;  2OOQ A;  2FJM A;  4JNB A;  1FPR A;  2HVL A;  3ZV2 A;  2NLK A;  5I6V A;  1ECV A;  4PYH A;  2FJN A;  2H03 A;  4OHH A;  3F81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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