3I80A

Protein tyrosine phosphatase 1b - transition state analog for the second catalytic step
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
298
structure length
298
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 109
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3i80A00
3BLUA 1BZCA 1P15A 2B4OA 2E0TA 2VEXA 2I4EA 2A8BA 1BZHA 1OHEA 4GRZA 3S3KA 3O4TA 2B4UA 4WU3A 4Z6BA 4RHGA 4YR8B 3H2XA 1C85A 3ZM1A 2CNFA 5KA3A 5LXQB 3MMJA 1OHCA 2F6ZA 4OHDA 5K23A 1NWEA 2QCJA 1GWZA 2Y2FA 3V0HA 5AWXA 4KYRA 2F6YA 2P4DA 3NMEA 3QCEA 4R30A 1RPMA 5K25A 1GFYA 4MBBA 2CMCA 1C84A 2I6IA 2HC2A 5K9WA 2CFVA 2GWOA 3S4EA 3I36A 3ZM2A 1G1GA 1OETA 1U24A 3QCJA 1Q6PA 4WTYA 4GFVA 3QCLA 5BZXA 1ONYA 3QCDA 3QCMA 1ECVA 3RO1A 2QCTA 2NT7A 1G1FA 3ZV2A 2I6PA 2B3OA 2CNHA 2H03A 1EENA 4GE5A 1OEVA 1G4US 2QDPA 1OEUA 1XRIA 2H04A 5KAAA 2BGEA 1Q6JA 1YN9A 2YDUA 2QBRA 3ZM3A 1LARA 1VHRA 3D44A 3I7ZA 2RF6A 2QBQA 4S0GA 3QKPA 1ZC0A 2G6ZA 4H1OA 5K24A 5K9VA 3LJ8A 3O4SA 2GJTA 1PTTA 3RGOA 2OUDA 4GWFA 2NZ6A 4NNDA 4WOHA 1NWLA 5IBMA 1PXHA 2BZLA 4ICZA 2NV5A 1XBOA 4HJQA 3S3HA 2F6FA 1T49A 3I80A 3BM8A 4RI4A 2CM7A 2I4HA 2I6MA 3EU0A 3MOZA 2I6JA 5HDEA 3S3FA 2IMGA 2I75A 2F6WA 3V0IA 3A5KA 3BRHA 4J51A 3GXGA 1JF7A 1NO6A 4NWFA 2C7SA 1JLNA 2B4SA 3EAXA 4KYQA 1Q6MA 1PTYA 2BV5A 1PTVA 5KA2A 4OHEA 4D3QA 2JJDA 1I9SA 1PH0A 2H4KA 3V0DA 1YTSA 4GS0A 3QCIA 4QBWA 2P6XA 1OHDA 3O3LA 4OHHA 4RI5A 1J4XA 2QBPA 2WGPA 4NYHA 2I5XA 4QAPA 4Y14A 1Q1MA 5IBSA 2CNEA 4JNBA 2F70A 3ZMPA 2J16A 2CMBA 2VEUA 3O4UA 5EHRA 2G59A 3F9BA 5I6VA 5KA1A 4RH9A 2CM3A 1C86A 2CNIA 4R0TA 1T48A 2OZ5A 3O5XA 2Q47A 1QZ0A 2BGDA 3QCNA 4OHLA 2B49A 3D42A 4DGXA 1ZCLA 1OEOX 4ZRTA 1XXPA 1L8KA 4Y2EA 1G4WR 2QBSA 3N0AA 2R0BA 5KA7A 4D3PA 2J17A 4PVGA 2CMAA 2HNQA 2Y96A 1V3AA 2HC1A 1R6HA 2HXPA 2PQ5A 1ONZA 4PYHA 1A5YA 1T4JA 3ZMQA 4HJPA 4NWGA 1I9TA 3OMHA 2NT2A 2HCMA 2QDMA 3PS5A 1Q6SA 2AHSA 2FJNA 1YWFA 4GE6A 2FH7A 4QBEA 4R0SA 2HY3A 1NNYA 1XM2A 2CNGA 1KAVA 3V0JA 2VEYA 1YFOA 3S3EA 2PA5A 3V0EA 2F71A 2H4GA 3S4OA 1YGRA 3V0FA 2I3UA 4JMKA 4TVVA 3M4UA 3A5JA 4H34A 5KABA 5K22A 1OESA 1M3GA 1FPZA 1NL9A 3OLRA 4AZ1A 4RH5A 3QCFA 2QEPA 2Q05A 4WU2A 2BIJA 1Q6TA 1ZCKA 1PA9A 4HRFA 4GRYA 4ERCA 4KI9A 4NX8A 3EMUA 3B7OA 3RGQA 4B04A 3MOWA 1AAXA 4RKKA 1EEOA 2M3VA 2OOQA 2H02A 1NZ7A 2AZRA 1FQ1A 4YAAA 1PTUA 1QXKA 2MBCA 2A3KA 1Q6NA 5BZZA 3RZ2A 1LYVA 5KA0A 2F6TA 1L8GA 2PSZA 3F9AA 1D5RA 4IKCA 4ZI4A 3EB1A 5KA8A 4JMJA 4GFUA 4QAHA 1XXVA 2CM2A 4ZN5A 1G1HA 3GXHA 3AWEA 3AWFA 2HB1A 4DGPA 5GTJA 3SMEA 2NLKA 1PA1A 3AWGA 1YZ4A 3QCKA 2F6VA 2C46A 1U25A 1KAKA 1C83A 1WRMA 4I8NA 4BPCA 2HVLA 2I1YA 2HNPA 1SUGA 1X24A 2ESBA 2GP0A 2NTAA 2VEVA 5EHPA 2I3RA 3QKQA 2PT0A 5BX1A 1WAXA 1YGUA 1C88A 2VEWA 2OC3A 1MKPA 4OHIA 1G7GA 1YTNA 2B4PA 1YTWA 3D1HA 3F41A 5MMZB 4QUNA 1WCHA 2I4GA 2SHPA 1PYNA 2I6OA 2DXPA 2ZMMA 3SR9A 2CM8A 2QDCA 4JBCA 4BJOA 1C87A 2B07A 1ZZWA 3D1QA 2PI7A 3D9CA 2CJZA 3U96A 2PBNA 5KACA 3QCCA 4GE2A 3V0GA 3ZM0A 4D3RA 3F81A 1U26A 1FPRA 2H4VA 1OEMX 4RDDA 1I57A 3QCBA 2I42A 3QCHA 1YPTA 3EZZA 3BLTA 5J8RA 2FJMA 2J16B 3D1OA 5M43A 4QUMA 5KA9A 2F46A 5BUGA 2ZN7A 5KA4A 3QCGA 3CWEA 3CM3A 1RXDA 1LQFA 1G7FA 3F99A 1BZJA 5KADA
chains in the Genus database with same CATH superfamily
3BLUA 1BZCA 4ZIYA 1P15A 2B4OA 2E0TA 1E8CA 2VEXA 2I4EA 2A8BA 1BZHA 1OHEA 2GCBA 4GRZA 3S3KA 3O4TA 1P3DA 2B4UA 4WU3A 4Z6BA 4RHGA 4YR8B 3H2XA 1C85A 3ZM1A 2CNFA 5KA3A 5LXQB 3MMJA 3ZM6A 2UUOA 1OHCA 2F6ZA 4OHDA 2VTEA 5K23A 1NWEA 2QCJA 1GWZA 2Y2FA 3V0HA 5AWXA 4KYRA 2F6YA 2P4DA 3NMEA 3ZL8A 3QCEA 4BUBA 3PYZA 4R30A 1RPMA 5K25A 1GFYA 4MBBA 2CMCA 1C84A 2I6IA 2HC2A 5K9WA 2CFVA 2GCAA 2GWOA 3S4EA 3I36A 3ZM2A 1G1GA 1OETA 1U24A 3QCJA 1Q6PA 4WTYA 4GFVA 3QCLA 5BZXA 1ONYA 3QCDA 3QCMA 1ECVA 3RO1A 2QCTA 2NT7A 2UUPA 1G1FA 3ZV2A 2I6PA 4BUCA 2B3OA 2CNHA 2H03A 1EENA 4GE5A 1OEVA 1G4US 2JFGA 2QDPA 1OEUA 1XRIA 2H04A 5KAAA 1J6UA 2BGEA 1W7KA 1Q6JA 1YN9A 2YDUA 2XPCA 2QBRA 3ZM3A 1LARA 1VHRA 3D44A 3I7ZA 2RF6A 2QBQA 4S0GA 3QKPA 1ZC0A 2G6ZA 4H1OA 5K24A 5K9VA 3LJ8A 3O4SA 2GJTA 1PTTA 3RGOA 4QDIA 2OUDA 4GWFA 2NZ6A 4NNDA 4WOHA 1GG4A 1UAGA 1NWLA 5IBMA 3ZM5A 1PXHA 2BZLA 4ICZA 2NV5A 1XBOA 4HJQA 3S3HA 2Y66A 2F6FA 1T49A 3I80A 4UAGA 2F00A 2AM2A 3BM8A 4RI4A 2CM7A 1E0DA 2I4HA 2I6MA 3EU0A 1FGSA 3MOZA 2I6JA 5HDEA 3S3FA 2IMGA 2I75A 2F6WA 3V0IA 3A5KA 3BRHA 4J51A 3GXGA 1JF7A 1NO6A 4NWFA 2C7SA 1JLNA 2B4SA 3EAXA 4KYQA 1Q6MA 1PTYA 2BV5A 4CVLA 1PTVA 5KA2A 4OHEA 4D3QA 2JJDA 1I9SA 1PH0A 2H4KA 2WJPA 3V0DA 1JBWA 1YTSA 4GS0A 3QCIA 4QBWA 2P6XA 3MVNA 1OHDA 3O3LA 4OHHA 4RI5A 1J4XA 3LK7A 2QBPA 2WGPA 4NYHA 2I5XA 4QAPA 4Y14A 1Q1MA 5IBSA 2CNEA 4JNBA 2F70A 3ZMPA 2J16A 2CMBA 2VEUA 3O4UA 5EHRA 2G59A 3F9BA 5I6VA 5KA1A 4RH9A 2CM3A 1C86A 2CNIA 4R0TA 1T48A 2WTZA 2OZ5A 3O5XA 2Q47A 1QZ0A 2BGDA 3QCNA 1GQYA 4OHLA 2B49A 3D42A 4DGXA 1ZCLA 1OEOX 4ZRTA 1XXPA 1L8KA 4Y2EA 1G4WR 1EEHA 2QBSA 3N0AA 2R0BA 5KA7A 4D3PA 2J17A 4PVGA 2CMAA 2XJAA 2HNQA 2Y96A 1V3AA 2HC1A 1R6HA 2HXPA 2PQ5A 1ONZA 4PYHA 1A5YA 1T4JA 3ZMQA 1P31A 4HJPA 4NWGA 1I9TA 3OMHA 2VORA 4CVKA 2NT2A 2HCMA 2QDMA 3PS5A 1Q6SA 2AHSA 2FJNA 1YWFA 4GE6A 2FH7A 4QBEA 4R0SA 2HY3A 1NNYA 1XM2A 2CNGA 1KAVA 3V0JA 2VEYA 1YFOA 3S3EA 2PA5A 3V0EA 2F71A 2H4GA 3S4OA 1YGRA 3V0FA 1JBVA 2I3UA 4JMKA 4TVVA 3M4UA 3A5JA 4H34A 5KABA 5K22A 1OESA 1M3GA 1FPZA 1NL9A 3OLRA 4AZ1A 4RH5A 3QCFA 2QEPA 2Q05A 4WU2A 2BIJA 1Q6TA 1ZCKA 4QF5A 1PA9A 4HRFA 4GRYA 4ERCA 4KI9A 4NX8A 3EMUA 3B7OA 3RGQA 4B04A 3MOWA 1AAXA 4RKKA 1EEOA 2M3VA 2OOQA 2X5OA 2H02A 1NZ7A 2AZRA 1FQ1A 4YAAA 1PTUA 1QXKA 2MBCA 2A3KA 1Q6NA 5BZZA 3RZ2A 1LYVA 5KA0A 2F6TA 1L8GA 2PSZA 3F9AA 1D5RA 4IKCA 4ZI4A 3N2AA 3EB1A 5KA8A 4JMJA 4GFUA 2Y68A 4QAHA 2UAGA 1XXVA 2CM2A 4ZN5A 1G1HA 3GXHA 4C13A 3AWEA 4CVMA 3AWFA 2HB1A 5A5FA 4DGPA 5GTJA 3SMEA 2NLKA 1PA1A 2VOSA 3AWGA 1YZ4A 2GC5A 2GC6A 3QCKA 2F6VA 1O5ZA 2C46A 1U25A 1KAKA 1C83A 1WRMA 4I8NA 4BPCA 3HN7A 2HVLA 2I1YA 2HNPA 1SUGA 3QCZA 1X24A 2ESBA 4HV4A 2GP0A 2NTAA 2Y67A 2Y1OA 2VEVA 5EHPA 2I3RA 3QKQA 2PT0A 5BX1A 1WAXA 1YGUA 1C88A 2VEWA 5A5EA 2JFFA 2OC3A 1MKPA 4OHIA 2JFHA 1G7GA 1YTNA 2B4PA 1YTWA 3D1HA 3F41A 5MMZB 4QUNA 1WCHA 2I4GA 2SHPA 1PYNA 2I6OA 2DXPA 2ZMMA 3SR9A 2AM1A 2CM8A 2QDCA 4JBCA 4BJOA 1C87A 2B07A 1ZZWA 3NRSA 4C12A 3D1QA 2PI7A 3D9CA 2CJZA 3U96A 2PBNA 5KACA 3QCCA 4GE2A 1W78A 3V0GA 3ZM0A 4D3RA 3F81A 1U26A 1FPRA 2H4VA 1OEMX 4RDDA 1I57A 3QCBA 1GQQA 2I42A 3QCHA 3UAGA 1YPTA 3EZZA 3BLTA 5J8RA 2FJMA 2J16B 2VTDA 3D1OA 5M43A 4QUMA 5KA9A 2F46A 5BUGA 2ZN7A 5KA4A 3QCGA 3CWEA 3CM3A 1RXDA 1LQFA 1G7FA 3F99A 1BZJA 5KADA
chains in the Genus database with same CATH topology
3BLUA 1BZCA 1P15A 2B4OA 2E0TA 2VEXA 2I4EA 2A8BA 1BZHA 1OHEA 4GRZA 3S3KA 3O4TA 2B4UA 4WU3A 4Z6BA 4RHGA 4YR8B 3H2XA 1C85A 3ZM1A 2CNFA 5KA3A 5LXQB 3MMJA 1OHCA 2F6ZA 4OHDA 5K23A 1NWEA 2QCJA 1GWZA 2Y2FA 3V0HA 5AWXA 4KYRA 2F6YA 2P4DA 3NMEA 3QCEA 4R30A 1RPMA 5K25A 1GFYA 4MBBA 2CMCA 1C84A 2I6IA 2HC2A 5K9WA 2CFVA 2GWOA 3S4EA 3I36A 3ZM2A 1G1GA 1OETA 1U24A 3QCJA 1Q6PA 4WTYA 4GFVA 3QCLA 5BZXA 1ONYA 3QCDA 3QCMA 1ECVA 3RO1A 2QCTA 2NT7A 1G1FA 3ZV2A 2I6PA 2B3OA 2CNHA 2H03A 1EENA 4GE5A 1OEVA 1G4US 2QDPA 1OEUA 1XRIA 2H04A 5KAAA 2BGEA 1Q6JA 1YN9A 2YDUA 2QBRA 3ZM3A 1LARA 1VHRA 3D44A 3I7ZA 2RF6A 2QBQA 4S0GA 3QKPA 1ZC0A 2G6ZA 4H1OA 5K24A 5K9VA 3LJ8A 3O4SA 2GJTA 1PTTA 3RGOA 2OUDA 4GWFA 2NZ6A 4NNDA 4WOHA 1NWLA 5IBMA 1PXHA 2BZLA 4ICZA 2NV5A 1XBOA 4HJQA 3S3HA 2F6FA 1T49A 3I80A 3BM8A 4RI4A 2CM7A 2I4HA 2I6MA 3EU0A 3MOZA 2I6JA 5HDEA 3S3FA 2IMGA 2I75A 2F6WA 3V0IA 3A5KA 3BRHA 4J51A 3GXGA 1JF7A 1NO6A 4NWFA 2C7SA 1JLNA 2B4SA 3EAXA 4KYQA 1Q6MA 1PTYA 2BV5A 1PTVA 5KA2A 4OHEA 4D3QA 2JJDA 1I9SA 1PH0A 2H4KA 3V0DA 1YTSA 4GS0A 3QCIA 4QBWA 2P6XA 1OHDA 3O3LA 4OHHA 4RI5A 1J4XA 2QBPA 2WGPA 4NYHA 2I5XA 4QAPA 4Y14A 1Q1MA 5IBSA 2CNEA 4JNBA 2F70A 3ZMPA 2J16A 2CMBA 2VEUA 3O4UA 5EHRA 2G59A 3F9BA 5I6VA 5KA1A 4RH9A 2CM3A 1C86A 2CNIA 4R0TA 1T48A 2OZ5A 3O5XA 2Q47A 1QZ0A 2BGDA 3QCNA 4OHLA 2B49A 3D42A 4DGXA 1ZCLA 1OEOX 4ZRTA 1XXPA 1L8KA 4Y2EA 1G4WR 2QBSA 3N0AA 2R0BA 5KA7A 4D3PA 2J17A 4PVGA 2CMAA 2HNQA 2Y96A 1V3AA 2HC1A 1R6HA 2HXPA 2PQ5A 1ONZA 4PYHA 1A5YA 1T4JA 3ZMQA 4HJPA 4NWGA 1I9TA 3OMHA 2NT2A 2HCMA 2QDMA 3PS5A 1Q6SA 2AHSA 2FJNA 1YWFA 4GE6A 2FH7A 4QBEA 4R0SA 2HY3A 1NNYA 1XM2A 2CNGA 1KAVA 3V0JA 2VEYA 1YFOA 3S3EA 2PA5A 3V0EA 2F71A 2H4GA 3S4OA 1YGRA 3V0FA 2I3UA 4JMKA 4TVVA 3M4UA 3A5JA 4H34A 5KABA 5K22A 1OESA 1M3GA 1FPZA 1NL9A 3OLRA 4AZ1A 4RH5A 3QCFA 2QEPA 2Q05A 4WU2A 2BIJA 1Q6TA 1ZCKA 1PA9A 4HRFA 4GRYA 4ERCA 4KI9A 4NX8A 3EMUA 3B7OA 3RGQA 4B04A 3MOWA 1AAXA 4RKKA 1EEOA 2M3VA 2OOQA 2H02A 1NZ7A 2AZRA 1FQ1A 4YAAA 1PTUA 1QXKA 2MBCA 2A3KA 1Q6NA 5BZZA 3RZ2A 1LYVA 5KA0A 2F6TA 1L8GA 2PSZA 3F9AA 1D5RA 4IKCA 4ZI4A 3EB1A 5KA8A 4JMJA 4GFUA 4QAHA 1XXVA 2CM2A 4ZN5A 1G1HA 3GXHA 3AWEA 3AWFA 2HB1A 4DGPA 5GTJA 3SMEA 2NLKA 1PA1A 3AWGA 1YZ4A 3QCKA 2F6VA 2C46A 1U25A 1KAKA 1C83A 1WRMA 4I8NA 4BPCA 2HVLA 2I1YA 2HNPA 1SUGA 1X24A 2ESBA 2GP0A 2NTAA 2VEVA 5EHPA 2I3RA 3QKQA 2PT0A 5BX1A 1WAXA 1YGUA 1C88A 2VEWA 2OC3A 1MKPA 4OHIA 1G7GA 1YTNA 2B4PA 1YTWA 3D1HA 3F41A 5MMZB 4QUNA 1WCHA 2I4GA 2SHPA 1PYNA 2I6OA 2DXPA 2ZMMA 3SR9A 2CM8A 2QDCA 4JBCA 4BJOA 1C87A 2B07A 1ZZWA 3D1QA 2PI7A 3D9CA 2CJZA 3U96A 2PBNA 5KACA 3QCCA 4GE2A 3V0GA 3ZM0A 4D3RA 3F81A 1U26A 1FPRA 2H4VA 1OEMX 4RDDA 1I57A 3QCBA 2I42A 3QCHA 1YPTA 3EZZA 3BLTA 5J8RA 2FJMA 2J16B 3D1OA 5M43A 4QUMA 5KA9A 2F46A 5BUGA 2ZN7A 5KA4A 3QCGA 3CWEA 3CM3A 1RXDA 1LQFA 1G7FA 3F99A 1BZJA 5KADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BLU A;  1BZC A;  1P15 A;  2B4O A;  2E0T A;  2VEX A;  2I4E A;  2A8B A;  1BZH A;  1OHE A;  4GRZ A;  3S3K A;  3O4T A;  2B4U A;  4WU3 A;  4Z6B A;  4RHG A;  4YR8 B;  3H2X A;  1C85 A;  3ZM1 A;  2CNF A;  5KA3 A;  5LXQ B;  3MMJ A;  1OHC A;  2F6Z A;  4OHD A;  5K23 A;  1NWE A;  2QCJ A;  1GWZ A;  2Y2F A;  3V0H A;  5AWX A;  4KYR A;  2F6Y A;  2P4D A;  3NME A;  3QCE A;  4R30 A;  1RPM A;  5K25 A;  1GFY A;  4MBB A;  2CMC A;  1C84 A;  2I6I A;  2HC2 A;  5K9W A;  2CFV A;  2GWO A;  3S4E A;  3I36 A;  3ZM2 A;  1G1G A;  1OET A;  1U24 A;  3QCJ A;  1Q6P A;  4WTY A;  4GFV A;  3QCL A;  5BZX A;  1ONY A;  3QCD A;  3QCM A;  1ECV A;  3RO1 A;  2QCT A;  2NT7 A;  1G1F A;  3ZV2 A;  2I6P A;  2B3O A;  2CNH A;  2H03 A;  1EEN A;  4GE5 A;  1OEV A;  1G4U S;  2QDP A;  1OEU A;  1XRI A;  2H04 A;  5KAA A;  2BGE A;  1Q6J A;  1YN9 A;  2YDU A;  2QBR A;  3ZM3 A;  1LAR A;  1VHR A;  3D44 A;  3I7Z A;  2RF6 A;  2QBQ A;  4S0G A;  3QKP A;  1ZC0 A;  2G6Z A;  4H1O A;  5K24 A;  5K9V A;  3LJ8 A;  3O4S A;  2GJT A;  1PTT A;  3RGO A;  2OUD A;  4GWF A;  2NZ6 A;  4NND A;  4WOH A;  1NWL A;  5IBM A;  1PXH A;  2BZL A;  4ICZ A;  2NV5 A;  1XBO A;  4HJQ A;  3S3H A;  2F6F A;  1T49 A;  3I80 A;  3BM8 A;  4RI4 A;  2CM7 A;  2I4H A;  2I6M A;  3EU0 A;  3MOZ A;  2I6J A;  5HDE A;  3S3F A;  2IMG A;  2I75 A;  2F6W A;  3V0I A;  3A5K A;  3BRH A;  4J51 A;  3GXG A;  1JF7 A;  1NO6 A;  4NWF A;  2C7S A;  1JLN A;  2B4S A;  3EAX A;  4KYQ A;  1Q6M A;  1PTY A;  2BV5 A;  1PTV A;  5KA2 A;  4OHE A;  4D3Q A;  2JJD A;  1I9S A;  1PH0 A;  2H4K A;  3V0D A;  1YTS A;  4GS0 A;  3QCI A;  4QBW A;  2P6X A;  1OHD A;  3O3L A;  4OHH A;  4RI5 A;  1J4X A;  2QBP A;  2WGP A;  4NYH A;  2I5X A;  4QAP A;  4Y14 A;  1Q1M A;  5IBS A;  2CNE A;  4JNB A;  2F70 A;  3ZMP A;  2J16 A;  2CMB A;  2VEU A;  3O4U A;  5EHR A;  2G59 A;  3F9B A;  5I6V A;  5KA1 A;  4RH9 A;  2CM3 A;  1C86 A;  2CNI A;  4R0T A;  1T48 A;  2OZ5 A;  3O5X A;  2Q47 A;  1QZ0 A;  2BGD A;  3QCN A;  4OHL A;  2B49 A;  3D42 A;  4DGX A;  1ZCL A;  1OEO X;  4ZRT A;  1XXP A;  1L8K A;  4Y2E A;  1G4W R;  2QBS A;  3N0A A;  2R0B A;  5KA7 A;  4D3P A;  2J17 A;  4PVG A;  2CMA A;  2HNQ A;  2Y96 A;  1V3A A;  2HC1 A;  1R6H A;  2HXP A;  2PQ5 A;  1ONZ A;  4PYH A;  1A5Y A;  1T4J A;  3ZMQ A;  4HJP A;  4NWG A;  1I9T A;  3OMH A;  2NT2 A;  2HCM A;  2QDM A;  3PS5 A;  1Q6S A;  2AHS A;  2FJN A;  1YWF A;  4GE6 A;  2FH7 A;  4QBE A;  4R0S A;  2HY3 A;  1NNY A;  1XM2 A;  2CNG A;  1KAV A;  3V0J A;  2VEY A;  1YFO A;  3S3E A;  2PA5 A;  3V0E A;  2F71 A;  2H4G A;  3S4O A;  1YGR A;  3V0F A;  2I3U A;  4JMK A;  4TVV A;  3M4U A;  3A5J A;  4H34 A;  5KAB A;  5K22 A;  1OES A;  1M3G A;  1FPZ A;  1NL9 A;  3OLR A;  4AZ1 A;  4RH5 A;  3QCF A;  2QEP A;  2Q05 A;  4WU2 A;  2BIJ A;  1Q6T A;  1ZCK A;  1PA9 A;  4HRF A;  4GRY A;  4ERC A;  4KI9 A;  4NX8 A;  3EMU A;  3B7O A;  3RGQ A;  4B04 A;  3MOW A;  1AAX A;  4RKK A;  1EEO A;  2M3V A;  2OOQ A;  2H02 A;  1NZ7 A;  2AZR A;  1FQ1 A;  4YAA A;  1PTU A;  1QXK A;  2MBC A;  2A3K A;  1Q6N A;  5BZZ A;  3RZ2 A;  1LYV A;  5KA0 A;  2F6T A;  1L8G A;  2PSZ A;  3F9A A;  1D5R A;  4IKC A;  4ZI4 A;  3EB1 A;  5KA8 A;  4JMJ A;  4GFU A;  4QAH A;  1XXV A;  2CM2 A;  4ZN5 A;  1G1H A;  3GXH A;  3AWE A;  3AWF A;  2HB1 A;  4DGP A;  5GTJ A;  3SME A;  2NLK A;  1PA1 A;  3AWG A;  1YZ4 A;  3QCK A;  2F6V A;  2C46 A;  1U25 A;  1KAK A;  1C83 A;  1WRM A;  4I8N A;  4BPC A;  2HVL A;  2I1Y A;  2HNP A;  1SUG A;  1X24 A;  2ESB A;  2GP0 A;  2NTA A;  2VEV A;  5EHP A;  2I3R A;  3QKQ A;  2PT0 A;  5BX1 A;  1WAX A;  1YGU A;  1C88 A;  2VEW A;  2OC3 A;  1MKP A;  4OHI A;  1G7G A;  1YTN A;  2B4P A;  1YTW A;  3D1H A;  3F41 A;  5MMZ B;  4QUN A;  1WCH A;  2I4G A;  2SHP A;  1PYN A;  2I6O A;  2DXP A;  2ZMM A;  3SR9 A;  2CM8 A;  2QDC A;  4JBC A;  4BJO A;  1C87 A;  2B07 A;  1ZZW A;  3D1Q A;  2PI7 A;  3D9C A;  2CJZ A;  3U96 A;  2PBN A;  5KAC A;  3QCC A;  4GE2 A;  3V0G A;  3ZM0 A;  4D3R A;  3F81 A;  1U26 A;  1FPR A;  2H4V A;  1OEM X;  4RDD A;  1I57 A;  3QCB A;  2I42 A;  3QCH A;  1YPT A;  3EZZ A;  3BLT A;  5J8R A;  2FJM A;  2J16 B;  3D1O A;  5M43 A;  4QUM A;  5KA9 A;  2F46 A;  5BUG A;  2ZN7 A;  5KA4 A;  3QCG A;  3CWE A;  3CM3 A;  1RXD A;  1LQF A;  1G7F A;  3F99 A;  1BZJ A;  5KAD A; 
#chains in the Genus database with same CATH topology
 3BLU A;  1BZC A;  4ZIY A;  1P15 A;  2B4O A;  2E0T A;  1E8C A;  2VEX A;  2I4E A;  2A8B A;  1BZH A;  1OHE A;  2GCB A;  4GRZ A;  3S3K A;  3O4T A;  1P3D A;  2B4U A;  4WU3 A;  4Z6B A;  4RHG A;  4YR8 B;  3H2X A;  1C85 A;  3ZM1 A;  2CNF A;  5KA3 A;  5LXQ B;  3MMJ A;  3ZM6 A;  2UUO A;  1OHC A;  2F6Z A;  4OHD A;  2VTE A;  5K23 A;  1NWE A;  2QCJ A;  1GWZ A;  2Y2F A;  3V0H A;  5AWX A;  4KYR A;  2F6Y A;  2P4D A;  3NME A;  3ZL8 A;  3QCE A;  4BUB A;  3PYZ A;  4R30 A;  1RPM A;  5K25 A;  1GFY A;  4MBB A;  2CMC A;  1C84 A;  2I6I A;  2HC2 A;  5K9W A;  2CFV A;  2GCA A;  2GWO A;  3S4E A;  3I36 A;  3ZM2 A;  1G1G A;  1OET A;  1U24 A;  3QCJ A;  1Q6P A;  4WTY A;  4GFV A;  3QCL A;  5BZX A;  1ONY A;  3QCD A;  3QCM A;  1ECV A;  3RO1 A;  2QCT A;  2NT7 A;  2UUP A;  1G1F A;  3ZV2 A;  2I6P A;  4BUC A;  2B3O A;  2CNH A;  2H03 A;  1EEN A;  4GE5 A;  1OEV A;  1G4U S;  2JFG A;  2QDP A;  1OEU A;  1XRI A;  2H04 A;  5KAA A;  1J6U A;  2BGE A;  1W7K A;  1Q6J A;  1YN9 A;  2YDU A;  2XPC A;  2QBR A;  3ZM3 A;  1LAR A;  1VHR A;  3D44 A;  3I7Z A;  2RF6 A;  2QBQ A;  4S0G A;  3QKP A;  1ZC0 A;  2G6Z A;  4H1O A;  5K24 A;  5K9V A;  3LJ8 A;  3O4S A;  2GJT A;  1PTT A;  3RGO A;  4QDI A;  2OUD A;  4GWF A;  2NZ6 A;  4NND A;  4WOH A;  1GG4 A;  1UAG A;  1NWL A;  5IBM A;  3ZM5 A;  1PXH A;  2BZL A;  4ICZ A;  2NV5 A;  1XBO A;  4HJQ A;  3S3H A;  2Y66 A;  2F6F A;  1T49 A;  3I80 A;  4UAG A;  2F00 A;  2AM2 A;  3BM8 A;  4RI4 A;  2CM7 A;  1E0D A;  2I4H A;  2I6M A;  3EU0 A;  1FGS A;  3MOZ A;  2I6J A;  5HDE A;  3S3F A;  2IMG A;  2I75 A;  2F6W A;  3V0I A;  3A5K A;  3BRH A;  4J51 A;  3GXG A;  1JF7 A;  1NO6 A;  4NWF A;  2C7S A;  1JLN A;  2B4S A;  3EAX A;  4KYQ A;  1Q6M A;  1PTY A;  2BV5 A;  4CVL A;  1PTV A;  5KA2 A;  4OHE A;  4D3Q A;  2JJD A;  1I9S A;  1PH0 A;  2H4K A;  2WJP A;  3V0D A;  1JBW A;  1YTS A;  4GS0 A;  3QCI A;  4QBW A;  2P6X A;  3MVN A;  1OHD A;  3O3L A;  4OHH A;  4RI5 A;  1J4X A;  3LK7 A;  2QBP A;  2WGP A;  4NYH A;  2I5X A;  4QAP A;  4Y14 A;  1Q1M A;  5IBS A;  2CNE A;  4JNB A;  2F70 A;  3ZMP A;  2J16 A;  2CMB A;  2VEU A;  3O4U A;  5EHR A;  2G59 A;  3F9B A;  5I6V A;  5KA1 A;  4RH9 A;  2CM3 A;  1C86 A;  2CNI A;  4R0T A;  1T48 A;  2WTZ A;  2OZ5 A;  3O5X A;  2Q47 A;  1QZ0 A;  2BGD A;  3QCN A;  1GQY A;  4OHL A;  2B49 A;  3D42 A;  4DGX A;  1ZCL A;  1OEO X;  4ZRT A;  1XXP A;  1L8K A;  4Y2E A;  1G4W R;  1EEH A;  2QBS A;  3N0A A;  2R0B A;  5KA7 A;  4D3P A;  2J17 A;  4PVG A;  2CMA A;  2XJA A;  2HNQ A;  2Y96 A;  1V3A A;  2HC1 A;  1R6H A;  2HXP A;  2PQ5 A;  1ONZ A;  4PYH A;  1A5Y A;  1T4J A;  3ZMQ A;  1P31 A;  4HJP A;  4NWG A;  1I9T A;  3OMH A;  2VOR A;  4CVK A;  2NT2 A;  2HCM A;  2QDM A;  3PS5 A;  1Q6S A;  2AHS A;  2FJN A;  1YWF A;  4GE6 A;  2FH7 A;  4QBE A;  4R0S A;  2HY3 A;  1NNY A;  1XM2 A;  2CNG A;  1KAV A;  3V0J A;  2VEY A;  1YFO A;  3S3E A;  2PA5 A;  3V0E A;  2F71 A;  2H4G A;  3S4O A;  1YGR A;  3V0F A;  1JBV A;  2I3U A;  4JMK A;  4TVV A;  3M4U A;  3A5J A;  4H34 A;  5KAB A;  5K22 A;  1OES A;  1M3G A;  1FPZ A;  1NL9 A;  3OLR A;  4AZ1 A;  4RH5 A;  3QCF A;  2QEP A;  2Q05 A;  4WU2 A;  2BIJ A;  1Q6T A;  1ZCK A;  4QF5 A;  1PA9 A;  4HRF A;  4GRY A;  4ERC A;  4KI9 A;  4NX8 A;  3EMU A;  3B7O A;  3RGQ A;  4B04 A;  3MOW A;  1AAX A;  4RKK A;  1EEO A;  2M3V A;  2OOQ A;  2X5O A;  2H02 A;  1NZ7 A;  2AZR A;  1FQ1 A;  4YAA A;  1PTU A;  1QXK A;  2MBC A;  2A3K A;  1Q6N A;  5BZZ A;  3RZ2 A;  1LYV A;  5KA0 A;  2F6T A;  1L8G A;  2PSZ A;  3F9A A;  1D5R A;  4IKC A;  4ZI4 A;  3N2A A;  3EB1 A;  5KA8 A;  4JMJ A;  4GFU A;  2Y68 A;  4QAH A;  2UAG A;  1XXV A;  2CM2 A;  4ZN5 A;  1G1H A;  3GXH A;  4C13 A;  3AWE A;  4CVM A;  3AWF A;  2HB1 A;  5A5F A;  4DGP A;  5GTJ A;  3SME A;  2NLK A;  1PA1 A;  2VOS A;  3AWG A;  1YZ4 A;  2GC5 A;  2GC6 A;  3QCK A;  2F6V A;  1O5Z A;  2C46 A;  1U25 A;  1KAK A;  1C83 A;  1WRM A;  4I8N A;  4BPC A;  3HN7 A;  2HVL A;  2I1Y A;  2HNP A;  1SUG A;  3QCZ A;  1X24 A;  2ESB A;  4HV4 A;  2GP0 A;  2NTA A;  2Y67 A;  2Y1O A;  2VEV A;  5EHP A;  2I3R A;  3QKQ A;  2PT0 A;  5BX1 A;  1WAX A;  1YGU A;  1C88 A;  2VEW A;  5A5E A;  2JFF A;  2OC3 A;  1MKP A;  4OHI A;  2JFH A;  1G7G A;  1YTN A;  2B4P A;  1YTW A;  3D1H A;  3F41 A;  5MMZ B;  4QUN A;  1WCH A;  2I4G A;  2SHP A;  1PYN A;  2I6O A;  2DXP A;  2ZMM A;  3SR9 A;  2AM1 A;  2CM8 A;  2QDC A;  4JBC A;  4BJO A;  1C87 A;  2B07 A;  1ZZW A;  3NRS A;  4C12 A;  3D1Q A;  2PI7 A;  3D9C A;  2CJZ A;  3U96 A;  2PBN A;  5KAC A;  3QCC A;  4GE2 A;  1W78 A;  3V0G A;  3ZM0 A;  4D3R A;  3F81 A;  1U26 A;  1FPR A;  2H4V A;  1OEM X;  4RDD A;  1I57 A;  3QCB A;  1GQQ A;  2I42 A;  3QCH A;  3UAG A;  1YPT A;  3EZZ A;  3BLT A;  5J8R A;  2FJM A;  2J16 B;  2VTD A;  3D1O A;  5M43 A;  4QUM A;  5KA9 A;  2F46 A;  5BUG A;  2ZN7 A;  5KA4 A;  3QCG A;  3CWE A;  3CM3 A;  1RXD A;  1LQF A;  1G7F A;  3F99 A;  1BZJ A;  5KAD A; 
#chains in the Genus database with same CATH homology
 3BLU A;  1BZC A;  1P15 A;  2B4O A;  2E0T A;  2VEX A;  2I4E A;  2A8B A;  1BZH A;  1OHE A;  4GRZ A;  3S3K A;  3O4T A;  2B4U A;  4WU3 A;  4Z6B A;  4RHG A;  4YR8 B;  3H2X A;  1C85 A;  3ZM1 A;  2CNF A;  5KA3 A;  5LXQ B;  3MMJ A;  1OHC A;  2F6Z A;  4OHD A;  5K23 A;  1NWE A;  2QCJ A;  1GWZ A;  2Y2F A;  3V0H A;  5AWX A;  4KYR A;  2F6Y A;  2P4D A;  3NME A;  3QCE A;  4R30 A;  1RPM A;  5K25 A;  1GFY A;  4MBB A;  2CMC A;  1C84 A;  2I6I A;  2HC2 A;  5K9W A;  2CFV A;  2GWO A;  3S4E A;  3I36 A;  3ZM2 A;  1G1G A;  1OET A;  1U24 A;  3QCJ A;  1Q6P A;  4WTY A;  4GFV A;  3QCL A;  5BZX A;  1ONY A;  3QCD A;  3QCM A;  1ECV A;  3RO1 A;  2QCT A;  2NT7 A;  1G1F A;  3ZV2 A;  2I6P A;  2B3O A;  2CNH A;  2H03 A;  1EEN A;  4GE5 A;  1OEV A;  1G4U S;  2QDP A;  1OEU A;  1XRI A;  2H04 A;  5KAA A;  2BGE A;  1Q6J A;  1YN9 A;  2YDU A;  2QBR A;  3ZM3 A;  1LAR A;  1VHR A;  3D44 A;  3I7Z A;  2RF6 A;  2QBQ A;  4S0G A;  3QKP A;  1ZC0 A;  2G6Z A;  4H1O A;  5K24 A;  5K9V A;  3LJ8 A;  3O4S A;  2GJT A;  1PTT A;  3RGO A;  2OUD A;  4GWF A;  2NZ6 A;  4NND A;  4WOH A;  1NWL A;  5IBM A;  1PXH A;  2BZL A;  4ICZ A;  2NV5 A;  1XBO A;  4HJQ A;  3S3H A;  2F6F A;  1T49 A;  3I80 A;  3BM8 A;  4RI4 A;  2CM7 A;  2I4H A;  2I6M A;  3EU0 A;  3MOZ A;  2I6J A;  5HDE A;  3S3F A;  2IMG A;  2I75 A;  2F6W A;  3V0I A;  3A5K A;  3BRH A;  4J51 A;  3GXG A;  1JF7 A;  1NO6 A;  4NWF A;  2C7S A;  1JLN A;  2B4S A;  3EAX A;  4KYQ A;  1Q6M A;  1PTY A;  2BV5 A;  1PTV A;  5KA2 A;  4OHE A;  4D3Q A;  2JJD A;  1I9S A;  1PH0 A;  2H4K A;  3V0D A;  1YTS A;  4GS0 A;  3QCI A;  4QBW A;  2P6X A;  1OHD A;  3O3L A;  4OHH A;  4RI5 A;  1J4X A;  2QBP A;  2WGP A;  4NYH A;  2I5X A;  4QAP A;  4Y14 A;  1Q1M A;  5IBS A;  2CNE A;  4JNB A;  2F70 A;  3ZMP A;  2J16 A;  2CMB A;  2VEU A;  3O4U A;  5EHR A;  2G59 A;  3F9B A;  5I6V A;  5KA1 A;  4RH9 A;  2CM3 A;  1C86 A;  2CNI A;  4R0T A;  1T48 A;  2OZ5 A;  3O5X A;  2Q47 A;  1QZ0 A;  2BGD A;  3QCN A;  4OHL A;  2B49 A;  3D42 A;  4DGX A;  1ZCL A;  1OEO X;  4ZRT A;  1XXP A;  1L8K A;  4Y2E A;  1G4W R;  2QBS A;  3N0A A;  2R0B A;  5KA7 A;  4D3P A;  2J17 A;  4PVG A;  2CMA A;  2HNQ A;  2Y96 A;  1V3A A;  2HC1 A;  1R6H A;  2HXP A;  2PQ5 A;  1ONZ A;  4PYH A;  1A5Y A;  1T4J A;  3ZMQ A;  4HJP A;  4NWG A;  1I9T A;  3OMH A;  2NT2 A;  2HCM A;  2QDM A;  3PS5 A;  1Q6S A;  2AHS A;  2FJN A;  1YWF A;  4GE6 A;  2FH7 A;  4QBE A;  4R0S A;  2HY3 A;  1NNY A;  1XM2 A;  2CNG A;  1KAV A;  3V0J A;  2VEY A;  1YFO A;  3S3E A;  2PA5 A;  3V0E A;  2F71 A;  2H4G A;  3S4O A;  1YGR A;  3V0F A;  2I3U A;  4JMK A;  4TVV A;  3M4U A;  3A5J A;  4H34 A;  5KAB A;  5K22 A;  1OES A;  1M3G A;  1FPZ A;  1NL9 A;  3OLR A;  4AZ1 A;  4RH5 A;  3QCF A;  2QEP A;  2Q05 A;  4WU2 A;  2BIJ A;  1Q6T A;  1ZCK A;  1PA9 A;  4HRF A;  4GRY A;  4ERC A;  4KI9 A;  4NX8 A;  3EMU A;  3B7O A;  3RGQ A;  4B04 A;  3MOW A;  1AAX A;  4RKK A;  1EEO A;  2M3V A;  2OOQ A;  2H02 A;  1NZ7 A;  2AZR A;  1FQ1 A;  4YAA A;  1PTU A;  1QXK A;  2MBC A;  2A3K A;  1Q6N A;  5BZZ A;  3RZ2 A;  1LYV A;  5KA0 A;  2F6T A;  1L8G A;  2PSZ A;  3F9A A;  1D5R A;  4IKC A;  4ZI4 A;  3EB1 A;  5KA8 A;  4JMJ A;  4GFU A;  4QAH A;  1XXV A;  2CM2 A;  4ZN5 A;  1G1H A;  3GXH A;  3AWE A;  3AWF A;  2HB1 A;  4DGP A;  5GTJ A;  3SME A;  2NLK A;  1PA1 A;  3AWG A;  1YZ4 A;  3QCK A;  2F6V A;  2C46 A;  1U25 A;  1KAK A;  1C83 A;  1WRM A;  4I8N A;  4BPC A;  2HVL A;  2I1Y A;  2HNP A;  1SUG A;  1X24 A;  2ESB A;  2GP0 A;  2NTA A;  2VEV A;  5EHP A;  2I3R A;  3QKQ A;  2PT0 A;  5BX1 A;  1WAX A;  1YGU A;  1C88 A;  2VEW A;  2OC3 A;  1MKP A;  4OHI A;  1G7G A;  1YTN A;  2B4P A;  1YTW A;  3D1H A;  3F41 A;  5MMZ B;  4QUN A;  1WCH A;  2I4G A;  2SHP A;  1PYN A;  2I6O A;  2DXP A;  2ZMM A;  3SR9 A;  2CM8 A;  2QDC A;  4JBC A;  4BJO A;  1C87 A;  2B07 A;  1ZZW A;  3D1Q A;  2PI7 A;  3D9C A;  2CJZ A;  3U96 A;  2PBN A;  5KAC A;  3QCC A;  4GE2 A;  3V0G A;  3ZM0 A;  4D3R A;  3F81 A;  1U26 A;  1FPR A;  2H4V A;  1OEM X;  4RDD A;  1I57 A;  3QCB A;  2I42 A;  3QCH A;  1YPT A;  3EZZ A;  3BLT A;  5J8R A;  2FJM A;  2J16 B;  3D1O A;  5M43 A;  4QUM A;  5KA9 A;  2F46 A;  5BUG A;  2ZN7 A;  5KA4 A;  3QCG A;  3CWE A;  3CM3 A;  1RXD A;  1LQF A;  1G7F A;  3F99 A;  1BZJ A;  5KAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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