3LJ8A

Crystal structure of mkp-4
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
SFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase
total genus 50
structure length 146
sequence length 146
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3lj8A00
1A5YA 2F6VA 1PH0A 2H4VA 2QBQA 2GP0A 5BUGA 2A8BA 1OESA 2HVLA 3S3FA 2H03A 4KI9A 1U25A 2VEYA 4OHHA 4QAHA 5K9WA 1XM2A 3I80A 3AWEA 2PBNA 3BLUA 3QCHA 4ZI4A 4GFUA 1Q6PA 3V0EA 1NL9A 1KAVA 4QUNA 3D44A 1L8KA 3QCMA 5EHRA 3ZV2A 2CFVA 2OZ5A 3ZMPA 2I6IA 2JJDA 1ZZWA 1PYNA 2H4KA 2PI7A 2F6TA 2ZMMA 4RKKA 2Q05A 2R0BA 3S3KA 2P4DA 5HDEA 3LJ8A 2F6ZA 1C83A 4ERCA 1PA1A 4RH5A 5KA7A 5KACA 2NT2A 1YPTA 3S3HA 1VHRA 2VEXA 2BZLA 2GJTA 5EHPA 3RGQA 1EEOA 1YN9A 1ONZA 4BPCA 3MOZA 1OEMX 1FQ1A 3S3EA 3QCFA 5AWXA 5KA8A 2FJNA 3U96A 3H2XA 2B3OA 2YDUA 3SMEA 4H34A 3S4EA 2CNFA 5LXQB 2DXPA 1D5RA 4R30A 2MBCA 2NV5A 5IBMA 2HNPA 4TVVA 1KAKA 3QCCA 2H4GA 2QCTA 2B49A 2HB1A 2I3UA 2HC1A 3QCDA 2NLKA 5KADA 4ICZA 3O5XA 1OETA 1Q1MA 2C46A 1C86A 4OHEA 3D1QA 2BIJA 5BZXA 2A3KA 2B4OA 1T4JA 2J16A 3GXGA 4R0SA 2VEVA 3CWEA 4ZN5A 1JF7A 3O4SA 2F6FA 3V0IA 4QBWA 2I6OA 1ONYA 4GE5A 4D3QA 3BRHA 3F41A 4WOHA 3BM8A 4HJPA 2NTAA 4GRYA 3AWGA 2C7SA 1RXDA 2CM3A 1WCHA 3MMJA 2WGPA 3QCJA 1OEVA 3QKQA 3QCEA 3RGOA 2B4PA 1G7FA 3AWFA 3EB1A 5MMZB 4OHLA 3BLTA 4D3RA 4GWFA 2HXPA 3S4OA 3GXHA 4Y14A 4BJOA 1GWZA 2PQ5A 3D1OA 4KYRA 1I57A 1PTVA 3O4UA 2P6XA 3OMHA 2FJMA 1U26A 4PVGA 4QBEA 3I7ZA 2PSZA 1LARA 1I9SA 2BV5A 1C87A 2CMCA 2CNEA 2PA5A 1Q6TA 4OHIA 1YWFA 3D9CA 4JBCA 2HC2A 2Y96A 1Q6NA 1OHEA 3QCIA 4QUMA 3N0AA 3F81A 3RO1A 4JMJA 5K25A 5BX1A 1QXKA 2QDMA 1L8GA 2VEUA 3M4UA 3QCNA 1C84A 4MBBA 3F9AA 2B07A 2B4SA 2I5XA 5KA4A 4YAAA 1P15A 3V0FA 1OHCA 2J17A 1PA9A 2QDCA 2OC3A 4KYQA 2AZRA 2I4EA 5J8RA 2F6WA 4S0GA 1LQFA 1WRMA 2E0TA 2QBRA 2I6MA 3ZM2A 3QCGA 2F46A 1G4WR 3A5KA 1JLNA 2G6ZA 1MKPA 1YZ4A 4WU2A 1YTSA 1NNYA 2I4GA 2FH7A 2G59A 1AAXA 3F9BA 4RH9A 4RI5A 2NT7A 1I9TA 4NNDA 5K9VA 5KA3A 1LYVA 2CNHA 4NWGA 2ZN7A 2I4HA 3PS5A 1T49A 4QAPA 2HNQA 2SHPA 3QKPA 3I36A 4WU3A 1G1HA 5K23A 1XBOA 4PYHA 4RDDA 4D3PA 3V0GA 1J4XA 1Q6MA 5KABA 2CNGA 5KA1A 5KA0A 2QEPA 3QCKA 4JNBA 3V0HA 2J16B 2ESBA 3EZZA 2BGDA 1T48A 2M3VA 3OLRA 4NX8A 3NMEA 2B4UA 3ZMQA 1G4US 2H04A 1SUGA 1X24A 4GE2A 5BZZA 4YR8B 1GFYA 4NYHA 2AHSA 3CM3A 1G7GA 1V3AA 4JMKA 1ECVA 2F71A 4GRZA 1ZCLA 4GE6A 4R0TA 1FPZA 1XXPA 2HCMA 1Q6JA 4Y2EA 3O4TA 1BZCA 3MOWA 4RHGA 3ZM1A 2QBPA 2OOQA 3A5JA 3F99A 4H1OA 4RI4A 2I42A 2CMAA 2QCJA 2CM2A 1BZHA 1PTTA 1OHDA 3RZ2A 1OEOX 4B04A 1YGRA 2I6PA 1EENA 4J51A 5KA9A 3EAXA 5IBSA 3QCBA 2GWOA 3SR9A 2I1YA 2CNIA 1BZJA 4AZ1A 1R6HA 2PT0A 5KAAA 1FPRA 1NZ7A 1ZCKA 3B7OA 4DGPA 5KA2A 1XRIA 2Y2FA 2I75A 2Q47A 2CMBA 4WTYA 3O3LA 5K22A 2HY3A 3EU0A 2QDPA 2RF6A 3EMUA 4HRFA 4Z6BA 3QCLA 2I3RA 3D42A 1YTWA 4OHDA 5I6VA 5K24A 2I6JA 2F6YA 3V0JA 1NWEA 2QBSA 3V0DA 2H02A 4GS0A 3D1HA 1XXVA 3ZM3A 2VEWA 1YFOA 1NO6A 2NZ6A 1RPMA 2OUDA 1PXHA 1G1FA 1C88A 4IKCA 2CM7A 1YGUA 2BGEA 2IMGA 4I8NA 1QZ0A 1G1GA 2F70A 1ZC0A 4NWFA 1PTUA 5GTJA 1M3GA 1PTYA 1YTNA 1C85A 1WAXA 1OEUA 1U24A 5M43A 1Q6SA 4HJQA 2CM8A 4DGXA 4GFVA 3ZM0A 1NWLA 2CJZA 4ZRTA
chains in the Genus database with same CATH superfamily
1A5YA 2F6VA 2VTEA 2X5OA 1PH0A 2H4VA 2QBQA 2GC5A 2GP0A 5BUGA 2A8BA 1OESA 2HVLA 3S3FA 2H03A 4KI9A 4QF5A 1U25A 2VEYA 4OHHA 4QAHA 5K9WA 1XM2A 4CVKA 3I80A 3AWEA 2PBNA 3BLUA 3QCHA 4ZI4A 4GFUA 1Q6PA 3V0EA 1NL9A 1GG4A 1KAVA 4QUNA 3MVNA 3D44A 1L8KA 3QCMA 5EHRA 3ZV2A 2CFVA 2OZ5A 3ZMPA 1P31A 2I6IA 2JJDA 1ZZWA 1PYNA 3LK7A 3NRSA 2H4KA 2PI7A 2F6TA 2ZMMA 4RKKA 2Q05A 2R0BA 3S3KA 2P4DA 5HDEA 1P3DA 2F6ZA 3LJ8A 1C83A 4ERCA 2Y1OA 4CVLA 1PA1A 4RH5A 5KA7A 5KACA 2NT2A 1YPTA 3S3HA 1VHRA 2VEXA 2BZLA 2Y68A 2GJTA 5EHPA 3RGQA 1EEOA 1YN9A 1ONZA 3ZM5A 4BPCA 3MOZA 1OEMX 1FQ1A 3S3EA 3QCFA 5AWXA 5KA8A 2FJNA 3U96A 2UAGA 2AM2A 3H2XA 2B3OA 2YDUA 3SMEA 4H34A 3S4EA 2CNFA 5LXQB 2DXPA 1D5RA 4R30A 2MBCA 2NV5A 5IBMA 2HNPA 5A5FA 4TVVA 1KAKA 3PYZA 2GC6A 3QCCA 2H4GA 3ZL8A 2QCTA 2B49A 2HB1A 2I3UA 2HC1A 2GCBA 2VTDA 3QCDA 2NLKA 5KADA 4ICZA 3O5XA 1OETA 1Q1MA 2C46A 1C86A 4OHEA 3D1QA 2BIJA 5BZXA 2A3KA 2B4OA 1T4JA 2J16A 3GXGA 4R0SA 2VEVA 3CWEA 4ZN5A 1JF7A 3O4SA 2F6FA 4CVMA 1JBWA 3V0IA 4QBWA 2JFFA 2I6OA 1ONYA 4GE5A 4D3QA 3BRHA 3F41A 4WOHA 3BM8A 4HJPA 2UUOA 2NTAA 4GRYA 3AWGA 2C7SA 1RXDA 2CM3A 1WCHA 3MMJA 2WGPA 3QCJA 1OEVA 1J6UA 3QKQA 3QCEA 3RGOA 1FGSA 2B4PA 1G7FA 3AWFA 3EB1A 5MMZB 4OHLA 3BLTA 4D3RA 4GWFA 2HXPA 3S4OA 3GXHA 4Y14A 4BJOA 1GWZA 2PQ5A 3D1OA 4KYRA 1I57A 1PTVA 3O4UA 2P6XA 3OMHA 2FJMA 1U26A 4PVGA 4QBEA 3I7ZA 3N2AA 2PSZA 1LARA 1I9SA 2BV5A 1C87A 2CMCA 2CNEA 2PA5A 1Q6TA 4OHIA 1YWFA 2GCAA 3D9CA 4JBCA 2HC2A 2Y96A 1Q6NA 2VORA 1OHEA 3QCIA 4QUMA 3N0AA 3F81A 3RO1A 4JMJA 5K25A 5BX1A 1QXKA 2QDMA 1L8GA 2VEUA 3M4UA 3QCNA 1C84A 4MBBA 3F9AA 2B07A 2B4SA 2JFHA 2I5XA 5KA4A 4YAAA 1P15A 3V0FA 1OHCA 2J17A 1PA9A 2QDCA 1W7KA 2OC3A 4KYQA 2AZRA 2I4EA 5J8RA 2F6WA 4S0GA 1LQFA 1WRMA 2E0TA 2XJAA 2QBRA 4QDIA 2I6MA 3ZM2A 1UAGA 4BUBA 4HV4A 3QCGA 2F46A 1G4WR 3A5KA 1JLNA 2G6ZA 1MKPA 1YZ4A 4WU2A 1YTSA 1O5ZA 1NNYA 2I4GA 2FH7A 2G59A 1AAXA 3F9BA 4RH9A 4RI5A 2NT7A 1I9TA 4NNDA 5K9VA 1E0DA 1GQYA 4BUCA 2JFGA 5KA3A 1LYVA 2CNHA 4UAGA 4NWGA 2ZN7A 2I4HA 1JBVA 3PS5A 1T49A 4QAPA 2HNQA 2SHPA 3QKPA 3I36A 4WU3A 1G1HA 3QCZA 1XBOA 5K23A 4PYHA 4RDDA 4D3PA 3V0GA 1J4XA 1Q6MA 5KABA 2CNGA 5KA1A 5KA0A 2QEPA 3QCKA 4JNBA 3V0HA 2J16B 2ESBA 3EZZA 2BGDA 1T48A 2M3VA 3OLRA 4NX8A 3NMEA 2B4UA 3ZMQA 5A5EA 1G4US 2H04A 1SUGA 1X24A 4GE2A 2Y66A 5BZZA 4C12A 1GFYA 4NYHA 4YR8B 2AHSA 2UUPA 3CM3A 1G7GA 1V3AA 4JMKA 1ECVA 2F71A 4GRZA 1ZCLA 4GE6A 4R0TA 1FPZA 1XXPA 2HCMA 1Q6JA 4Y2EA 3O4TA 1BZCA 3MOWA 4RHGA 3ZM1A 2QBPA 2OOQA 3A5JA 3F99A 4H1OA 4RI4A 2I42A 2CMAA 2QCJA 2CM2A 2Y67A 1BZHA 1PTTA 3UAGA 1OHDA 3RZ2A 1OEOX 4B04A 1YGRA 2I6PA 1EENA 1GQQA 4J51A 5KA9A 3EAXA 2F00A 5IBSA 3QCBA 2GWOA 3SR9A 2I1YA 2CNIA 1BZJA 4AZ1A 3HN7A 1R6HA 2PT0A 5KAAA 1FPRA 1NZ7A 1ZCKA 3B7OA 4ZIYA 4DGPA 5KA2A 1XRIA 2Y2FA 2I75A 2Q47A 2CMBA 4WTYA 3O3LA 5K22A 2HY3A 3EU0A 2QDPA 2RF6A 3EMUA 4HRFA 4Z6BA 3QCLA 2I3RA 3D42A 1YTWA 1E8CA 4OHDA 5I6VA 5K24A 2I6JA 2AM1A 2F6YA 3V0JA 1NWEA 4C13A 2QBSA 2XPCA 3V0DA 2H02A 4GS0A 3D1HA 1XXVA 3ZM3A 2VEWA 1EEHA 1YFOA 1NO6A 2VOSA 2NZ6A 1RPMA 2OUDA 1PXHA 1G1FA 1C88A 4IKCA 2CM7A 3ZM6A 2WTZA 1YGUA 2BGEA 2IMGA 4I8NA 1QZ0A 1G1GA 2F70A 1ZC0A 2WJPA 4NWFA 1PTUA 5GTJA 1M3GA 1PTYA 1YTNA 1W78A 1C85A 1WAXA 1OEUA 1U24A 5M43A 1Q6SA 4HJQA 2CM8A 4DGXA 4GFVA 3ZM0A 1NWLA 2CJZA 4ZRTA
chains in the Genus database with same CATH topology
1A5YA 2F6VA 1PH0A 2H4VA 2QBQA 2GP0A 5BUGA 2A8BA 1OESA 2HVLA 3S3FA 2H03A 4KI9A 1U25A 2VEYA 4OHHA 4QAHA 5K9WA 1XM2A 3I80A 3AWEA 2PBNA 3BLUA 3QCHA 4ZI4A 4GFUA 1Q6PA 3V0EA 1NL9A 1KAVA 4QUNA 3D44A 1L8KA 3QCMA 5EHRA 3ZV2A 2CFVA 2OZ5A 3ZMPA 2I6IA 2JJDA 1ZZWA 1PYNA 2H4KA 2PI7A 2F6TA 2ZMMA 4RKKA 2Q05A 2R0BA 3S3KA 2P4DA 5HDEA 3LJ8A 2F6ZA 1C83A 4ERCA 1PA1A 4RH5A 5KA7A 5KACA 2NT2A 1YPTA 3S3HA 1VHRA 2VEXA 2BZLA 2GJTA 5EHPA 3RGQA 1EEOA 1YN9A 1ONZA 4BPCA 3MOZA 1OEMX 1FQ1A 3S3EA 3QCFA 5AWXA 5KA8A 2FJNA 3U96A 3H2XA 2B3OA 2YDUA 3SMEA 4H34A 3S4EA 2CNFA 5LXQB 2DXPA 1D5RA 4R30A 2MBCA 2NV5A 5IBMA 2HNPA 4TVVA 1KAKA 3QCCA 2H4GA 2QCTA 2B49A 2HB1A 2I3UA 2HC1A 3QCDA 2NLKA 5KADA 4ICZA 3O5XA 1OETA 1Q1MA 2C46A 1C86A 4OHEA 3D1QA 2BIJA 5BZXA 2A3KA 2B4OA 1T4JA 2J16A 3GXGA 4R0SA 2VEVA 3CWEA 4ZN5A 1JF7A 3O4SA 2F6FA 3V0IA 4QBWA 2I6OA 1ONYA 4GE5A 4D3QA 3BRHA 3F41A 4WOHA 3BM8A 4HJPA 2NTAA 4GRYA 3AWGA 2C7SA 1RXDA 2CM3A 1WCHA 3MMJA 2WGPA 3QCJA 1OEVA 3QKQA 3QCEA 3RGOA 2B4PA 1G7FA 3AWFA 3EB1A 5MMZB 4OHLA 3BLTA 4D3RA 4GWFA 2HXPA 3S4OA 3GXHA 4Y14A 4BJOA 1GWZA 2PQ5A 3D1OA 4KYRA 1I57A 1PTVA 3O4UA 2P6XA 3OMHA 2FJMA 1U26A 4PVGA 4QBEA 3I7ZA 2PSZA 1LARA 1I9SA 2BV5A 1C87A 2CMCA 2CNEA 2PA5A 1Q6TA 4OHIA 1YWFA 3D9CA 4JBCA 2HC2A 2Y96A 1Q6NA 1OHEA 3QCIA 4QUMA 3N0AA 3F81A 3RO1A 4JMJA 5K25A 5BX1A 1QXKA 2QDMA 1L8GA 2VEUA 3M4UA 3QCNA 1C84A 4MBBA 3F9AA 2B07A 2B4SA 2I5XA 5KA4A 4YAAA 1P15A 3V0FA 1OHCA 2J17A 1PA9A 2QDCA 2OC3A 4KYQA 2AZRA 2I4EA 5J8RA 2F6WA 4S0GA 1LQFA 1WRMA 2E0TA 2QBRA 2I6MA 3ZM2A 3QCGA 2F46A 1G4WR 3A5KA 1JLNA 2G6ZA 1MKPA 1YZ4A 4WU2A 1YTSA 1NNYA 2I4GA 2FH7A 2G59A 1AAXA 3F9BA 4RH9A 4RI5A 2NT7A 1I9TA 4NNDA 5K9VA 5KA3A 1LYVA 2CNHA 4NWGA 2ZN7A 2I4HA 3PS5A 1T49A 4QAPA 2HNQA 2SHPA 3QKPA 3I36A 4WU3A 1G1HA 5K23A 1XBOA 4PYHA 4RDDA 4D3PA 3V0GA 1J4XA 1Q6MA 5KABA 2CNGA 5KA1A 5KA0A 2QEPA 3QCKA 4JNBA 3V0HA 2J16B 2ESBA 3EZZA 2BGDA 1T48A 2M3VA 3OLRA 4NX8A 3NMEA 2B4UA 3ZMQA 1G4US 2H04A 1SUGA 1X24A 4GE2A 5BZZA 4YR8B 1GFYA 4NYHA 2AHSA 3CM3A 1G7GA 1V3AA 4JMKA 1ECVA 2F71A 4GRZA 1ZCLA 4GE6A 4R0TA 1FPZA 1XXPA 2HCMA 1Q6JA 4Y2EA 3O4TA 1BZCA 3MOWA 4RHGA 3ZM1A 2QBPA 2OOQA 3A5JA 3F99A 4H1OA 4RI4A 2I42A 2CMAA 2QCJA 2CM2A 1BZHA 1PTTA 1OHDA 3RZ2A 1OEOX 4B04A 1YGRA 2I6PA 1EENA 4J51A 5KA9A 3EAXA 5IBSA 3QCBA 2GWOA 3SR9A 2I1YA 2CNIA 1BZJA 4AZ1A 1R6HA 2PT0A 5KAAA 1FPRA 1NZ7A 1ZCKA 3B7OA 4DGPA 5KA2A 1XRIA 2Y2FA 2I75A 2Q47A 2CMBA 4WTYA 3O3LA 5K22A 2HY3A 3EU0A 2QDPA 2RF6A 3EMUA 4HRFA 4Z6BA 3QCLA 2I3RA 3D42A 1YTWA 4OHDA 5I6VA 5K24A 2I6JA 2F6YA 3V0JA 1NWEA 2QBSA 3V0DA 2H02A 4GS0A 3D1HA 1XXVA 3ZM3A 2VEWA 1YFOA 1NO6A 2NZ6A 1RPMA 2OUDA 1PXHA 1G1FA 1C88A 4IKCA 2CM7A 1YGUA 2BGEA 2IMGA 4I8NA 1QZ0A 1G1GA 2F70A 1ZC0A 4NWFA 1PTUA 5GTJA 1M3GA 1PTYA 1YTNA 1C85A 1WAXA 1OEUA 1U24A 5M43A 1Q6SA 4HJQA 2CM8A 4DGXA 4GFVA 3ZM0A 1NWLA 2CJZA 4ZRTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A5Y A;  2F6V A;  1PH0 A;  2H4V A;  2QBQ A;  2GP0 A;  5BUG A;  2A8B A;  1OES A;  2HVL A;  3S3F A;  2H03 A;  4KI9 A;  1U25 A;  2VEY A;  4OHH A;  4QAH A;  5K9W A;  1XM2 A;  3I80 A;  3AWE A;  2PBN A;  3BLU A;  3QCH A;  4ZI4 A;  4GFU A;  1Q6P A;  3V0E A;  1NL9 A;  1KAV A;  4QUN A;  3D44 A;  1L8K A;  3QCM A;  5EHR A;  3ZV2 A;  2CFV A;  2OZ5 A;  3ZMP A;  2I6I A;  2JJD A;  1ZZW A;  1PYN A;  2H4K A;  2PI7 A;  2F6T A;  2ZMM A;  4RKK A;  2Q05 A;  2R0B A;  3S3K A;  2P4D A;  5HDE A;  3LJ8 A;  2F6Z A;  1C83 A;  4ERC A;  1PA1 A;  4RH5 A;  5KA7 A;  5KAC A;  2NT2 A;  1YPT A;  3S3H A;  1VHR A;  2VEX A;  2BZL A;  2GJT A;  5EHP A;  3RGQ A;  1EEO A;  1YN9 A;  1ONZ A;  4BPC A;  3MOZ A;  1OEM X;  1FQ1 A;  3S3E A;  3QCF A;  5AWX A;  5KA8 A;  2FJN A;  3U96 A;  3H2X A;  2B3O A;  2YDU A;  3SME A;  4H34 A;  3S4E A;  2CNF A;  5LXQ B;  2DXP A;  1D5R A;  4R30 A;  2MBC A;  2NV5 A;  5IBM A;  2HNP A;  4TVV A;  1KAK A;  3QCC A;  2H4G A;  2QCT A;  2B49 A;  2HB1 A;  2I3U A;  2HC1 A;  3QCD A;  2NLK A;  5KAD A;  4ICZ A;  3O5X A;  1OET A;  1Q1M A;  2C46 A;  1C86 A;  4OHE A;  3D1Q A;  2BIJ A;  5BZX A;  2A3K A;  2B4O A;  1T4J A;  2J16 A;  3GXG A;  4R0S A;  2VEV A;  3CWE A;  4ZN5 A;  1JF7 A;  3O4S A;  2F6F A;  3V0I A;  4QBW A;  2I6O A;  1ONY A;  4GE5 A;  4D3Q A;  3BRH A;  3F41 A;  4WOH A;  3BM8 A;  4HJP A;  2NTA A;  4GRY A;  3AWG A;  2C7S A;  1RXD A;  2CM3 A;  1WCH A;  3MMJ A;  2WGP A;  3QCJ A;  1OEV A;  3QKQ A;  3QCE A;  3RGO A;  2B4P A;  1G7F A;  3AWF A;  3EB1 A;  5MMZ B;  4OHL A;  3BLT A;  4D3R A;  4GWF A;  2HXP A;  3S4O A;  3GXH A;  4Y14 A;  4BJO A;  1GWZ A;  2PQ5 A;  3D1O A;  4KYR A;  1I57 A;  1PTV A;  3O4U A;  2P6X A;  3OMH A;  2FJM A;  1U26 A;  4PVG A;  4QBE A;  3I7Z A;  2PSZ A;  1LAR A;  1I9S A;  2BV5 A;  1C87 A;  2CMC A;  2CNE A;  2PA5 A;  1Q6T A;  4OHI A;  1YWF A;  3D9C A;  4JBC A;  2HC2 A;  2Y96 A;  1Q6N A;  1OHE A;  3QCI A;  4QUM A;  3N0A A;  3F81 A;  3RO1 A;  4JMJ A;  5K25 A;  5BX1 A;  1QXK A;  2QDM A;  1L8G A;  2VEU A;  3M4U A;  3QCN A;  1C84 A;  4MBB A;  3F9A A;  2B07 A;  2B4S A;  2I5X A;  5KA4 A;  4YAA A;  1P15 A;  3V0F A;  1OHC A;  2J17 A;  1PA9 A;  2QDC A;  2OC3 A;  4KYQ A;  2AZR A;  2I4E A;  5J8R A;  2F6W A;  4S0G A;  1LQF A;  1WRM A;  2E0T A;  2QBR A;  2I6M A;  3ZM2 A;  3QCG A;  2F46 A;  1G4W R;  3A5K A;  1JLN A;  2G6Z A;  1MKP A;  1YZ4 A;  4WU2 A;  1YTS A;  1NNY A;  2I4G A;  2FH7 A;  2G59 A;  1AAX A;  3F9B A;  4RH9 A;  4RI5 A;  2NT7 A;  1I9T A;  4NND A;  5K9V A;  5KA3 A;  1LYV A;  2CNH A;  4NWG A;  2ZN7 A;  2I4H A;  3PS5 A;  1T49 A;  4QAP A;  2HNQ A;  2SHP A;  3QKP A;  3I36 A;  4WU3 A;  1G1H A;  5K23 A;  1XBO A;  4PYH A;  4RDD A;  4D3P A;  3V0G A;  1J4X A;  1Q6M A;  5KAB A;  2CNG A;  5KA1 A;  5KA0 A;  2QEP A;  3QCK A;  4JNB A;  3V0H A;  2J16 B;  2ESB A;  3EZZ A;  2BGD A;  1T48 A;  2M3V A;  3OLR A;  4NX8 A;  3NME A;  2B4U A;  3ZMQ A;  1G4U S;  2H04 A;  1SUG A;  1X24 A;  4GE2 A;  5BZZ A;  4YR8 B;  1GFY A;  4NYH A;  2AHS A;  3CM3 A;  1G7G A;  1V3A A;  4JMK A;  1ECV A;  2F71 A;  4GRZ A;  1ZCL A;  4GE6 A;  4R0T A;  1FPZ A;  1XXP A;  2HCM A;  1Q6J A;  4Y2E A;  3O4T A;  1BZC A;  3MOW A;  4RHG A;  3ZM1 A;  2QBP A;  2OOQ A;  3A5J A;  3F99 A;  4H1O A;  4RI4 A;  2I42 A;  2CMA A;  2QCJ A;  2CM2 A;  1BZH A;  1PTT A;  1OHD A;  3RZ2 A;  1OEO X;  4B04 A;  1YGR A;  2I6P A;  1EEN A;  4J51 A;  5KA9 A;  3EAX A;  5IBS A;  3QCB A;  2GWO A;  3SR9 A;  2I1Y A;  2CNI A;  1BZJ A;  4AZ1 A;  1R6H A;  2PT0 A;  5KAA A;  1FPR A;  1NZ7 A;  1ZCK A;  3B7O A;  4DGP A;  5KA2 A;  1XRI A;  2Y2F A;  2I75 A;  2Q47 A;  2CMB A;  4WTY A;  3O3L A;  5K22 A;  2HY3 A;  3EU0 A;  2QDP A;  2RF6 A;  3EMU A;  4HRF A;  4Z6B A;  3QCL A;  2I3R A;  3D42 A;  1YTW A;  4OHD A;  5I6V A;  5K24 A;  2I6J A;  2F6Y A;  3V0J A;  1NWE A;  2QBS A;  3V0D A;  2H02 A;  4GS0 A;  3D1H A;  1XXV A;  3ZM3 A;  2VEW A;  1YFO A;  1NO6 A;  2NZ6 A;  1RPM A;  2OUD A;  1PXH A;  1G1F A;  1C88 A;  4IKC A;  2CM7 A;  1YGU A;  2BGE A;  2IMG A;  4I8N A;  1QZ0 A;  1G1G A;  2F70 A;  1ZC0 A;  4NWF A;  1PTU A;  5GTJ A;  1M3G A;  1PTY A;  1YTN A;  1C85 A;  1WAX A;  1OEU A;  1U24 A;  5M43 A;  1Q6S A;  4HJQ A;  2CM8 A;  4DGX A;  4GFV A;  3ZM0 A;  1NWL A;  2CJZ A;  4ZRT A; 
#chains in the Genus database with same CATH topology
 1A5Y A;  2F6V A;  2VTE A;  2X5O A;  1PH0 A;  2H4V A;  2QBQ A;  2GC5 A;  2GP0 A;  5BUG A;  2A8B A;  1OES A;  2HVL A;  3S3F A;  2H03 A;  4KI9 A;  4QF5 A;  1U25 A;  2VEY A;  4OHH A;  4QAH A;  5K9W A;  1XM2 A;  4CVK A;  3I80 A;  3AWE A;  2PBN A;  3BLU A;  3QCH A;  4ZI4 A;  4GFU A;  1Q6P A;  3V0E A;  1NL9 A;  1GG4 A;  1KAV A;  4QUN A;  3MVN A;  3D44 A;  1L8K A;  3QCM A;  5EHR A;  3ZV2 A;  2CFV A;  2OZ5 A;  3ZMP A;  1P31 A;  2I6I A;  2JJD A;  1ZZW A;  1PYN A;  3LK7 A;  3NRS A;  2H4K A;  2PI7 A;  2F6T A;  2ZMM A;  4RKK A;  2Q05 A;  2R0B A;  3S3K A;  2P4D A;  5HDE A;  1P3D A;  2F6Z A;  3LJ8 A;  1C83 A;  4ERC A;  2Y1O A;  4CVL A;  1PA1 A;  4RH5 A;  5KA7 A;  5KAC A;  2NT2 A;  1YPT A;  3S3H A;  1VHR A;  2VEX A;  2BZL A;  2Y68 A;  2GJT A;  5EHP A;  3RGQ A;  1EEO A;  1YN9 A;  1ONZ A;  3ZM5 A;  4BPC A;  3MOZ A;  1OEM X;  1FQ1 A;  3S3E A;  3QCF A;  5AWX A;  5KA8 A;  2FJN A;  3U96 A;  2UAG A;  2AM2 A;  3H2X A;  2B3O A;  2YDU A;  3SME A;  4H34 A;  3S4E A;  2CNF A;  5LXQ B;  2DXP A;  1D5R A;  4R30 A;  2MBC A;  2NV5 A;  5IBM A;  2HNP A;  5A5F A;  4TVV A;  1KAK A;  3PYZ A;  2GC6 A;  3QCC A;  2H4G A;  3ZL8 A;  2QCT A;  2B49 A;  2HB1 A;  2I3U A;  2HC1 A;  2GCB A;  2VTD A;  3QCD A;  2NLK A;  5KAD A;  4ICZ A;  3O5X A;  1OET A;  1Q1M A;  2C46 A;  1C86 A;  4OHE A;  3D1Q A;  2BIJ A;  5BZX A;  2A3K A;  2B4O A;  1T4J A;  2J16 A;  3GXG A;  4R0S A;  2VEV A;  3CWE A;  4ZN5 A;  1JF7 A;  3O4S A;  2F6F A;  4CVM A;  1JBW A;  3V0I A;  4QBW A;  2JFF A;  2I6O A;  1ONY A;  4GE5 A;  4D3Q A;  3BRH A;  3F41 A;  4WOH A;  3BM8 A;  4HJP A;  2UUO A;  2NTA A;  4GRY A;  3AWG A;  2C7S A;  1RXD A;  2CM3 A;  1WCH A;  3MMJ A;  2WGP A;  3QCJ A;  1OEV A;  1J6U A;  3QKQ A;  3QCE A;  3RGO A;  1FGS A;  2B4P A;  1G7F A;  3AWF A;  3EB1 A;  5MMZ B;  4OHL A;  3BLT A;  4D3R A;  4GWF A;  2HXP A;  3S4O A;  3GXH A;  4Y14 A;  4BJO A;  1GWZ A;  2PQ5 A;  3D1O A;  4KYR A;  1I57 A;  1PTV A;  3O4U A;  2P6X A;  3OMH A;  2FJM A;  1U26 A;  4PVG A;  4QBE A;  3I7Z A;  3N2A A;  2PSZ A;  1LAR A;  1I9S A;  2BV5 A;  1C87 A;  2CMC A;  2CNE A;  2PA5 A;  1Q6T A;  4OHI A;  1YWF A;  2GCA A;  3D9C A;  4JBC A;  2HC2 A;  2Y96 A;  1Q6N A;  2VOR A;  1OHE A;  3QCI A;  4QUM A;  3N0A A;  3F81 A;  3RO1 A;  4JMJ A;  5K25 A;  5BX1 A;  1QXK A;  2QDM A;  1L8G A;  2VEU A;  3M4U A;  3QCN A;  1C84 A;  4MBB A;  3F9A A;  2B07 A;  2B4S A;  2JFH A;  2I5X A;  5KA4 A;  4YAA A;  1P15 A;  3V0F A;  1OHC A;  2J17 A;  1PA9 A;  2QDC A;  1W7K A;  2OC3 A;  4KYQ A;  2AZR A;  2I4E A;  5J8R A;  2F6W A;  4S0G A;  1LQF A;  1WRM A;  2E0T A;  2XJA A;  2QBR A;  4QDI A;  2I6M A;  3ZM2 A;  1UAG A;  4BUB A;  4HV4 A;  3QCG A;  2F46 A;  1G4W R;  3A5K A;  1JLN A;  2G6Z A;  1MKP A;  1YZ4 A;  4WU2 A;  1YTS A;  1O5Z A;  1NNY A;  2I4G A;  2FH7 A;  2G59 A;  1AAX A;  3F9B A;  4RH9 A;  4RI5 A;  2NT7 A;  1I9T A;  4NND A;  5K9V A;  1E0D A;  1GQY A;  4BUC A;  2JFG A;  5KA3 A;  1LYV A;  2CNH A;  4UAG A;  4NWG A;  2ZN7 A;  2I4H A;  1JBV A;  3PS5 A;  1T49 A;  4QAP A;  2HNQ A;  2SHP A;  3QKP A;  3I36 A;  4WU3 A;  1G1H A;  3QCZ A;  1XBO A;  5K23 A;  4PYH A;  4RDD A;  4D3P A;  3V0G A;  1J4X A;  1Q6M A;  5KAB A;  2CNG A;  5KA1 A;  5KA0 A;  2QEP A;  3QCK A;  4JNB A;  3V0H A;  2J16 B;  2ESB A;  3EZZ A;  2BGD A;  1T48 A;  2M3V A;  3OLR A;  4NX8 A;  3NME A;  2B4U A;  3ZMQ A;  5A5E A;  1G4U S;  2H04 A;  1SUG A;  1X24 A;  4GE2 A;  2Y66 A;  5BZZ A;  4C12 A;  1GFY A;  4NYH A;  4YR8 B;  2AHS A;  2UUP A;  3CM3 A;  1G7G A;  1V3A A;  4JMK A;  1ECV A;  2F71 A;  4GRZ A;  1ZCL A;  4GE6 A;  4R0T A;  1FPZ A;  1XXP A;  2HCM A;  1Q6J A;  4Y2E A;  3O4T A;  1BZC A;  3MOW A;  4RHG A;  3ZM1 A;  2QBP A;  2OOQ A;  3A5J A;  3F99 A;  4H1O A;  4RI4 A;  2I42 A;  2CMA A;  2QCJ A;  2CM2 A;  2Y67 A;  1BZH A;  1PTT A;  3UAG A;  1OHD A;  3RZ2 A;  1OEO X;  4B04 A;  1YGR A;  2I6P A;  1EEN A;  1GQQ A;  4J51 A;  5KA9 A;  3EAX A;  2F00 A;  5IBS A;  3QCB A;  2GWO A;  3SR9 A;  2I1Y A;  2CNI A;  1BZJ A;  4AZ1 A;  3HN7 A;  1R6H A;  2PT0 A;  5KAA A;  1FPR A;  1NZ7 A;  1ZCK A;  3B7O A;  4ZIY A;  4DGP A;  5KA2 A;  1XRI A;  2Y2F A;  2I75 A;  2Q47 A;  2CMB A;  4WTY A;  3O3L A;  5K22 A;  2HY3 A;  3EU0 A;  2QDP A;  2RF6 A;  3EMU A;  4HRF A;  4Z6B A;  3QCL A;  2I3R A;  3D42 A;  1YTW A;  1E8C A;  4OHD A;  5I6V A;  5K24 A;  2I6J A;  2AM1 A;  2F6Y A;  3V0J A;  1NWE A;  4C13 A;  2QBS A;  2XPC A;  3V0D A;  2H02 A;  4GS0 A;  3D1H A;  1XXV A;  3ZM3 A;  2VEW A;  1EEH A;  1YFO A;  1NO6 A;  2VOS A;  2NZ6 A;  1RPM A;  2OUD A;  1PXH A;  1G1F A;  1C88 A;  4IKC A;  2CM7 A;  3ZM6 A;  2WTZ A;  1YGU A;  2BGE A;  2IMG A;  4I8N A;  1QZ0 A;  1G1G A;  2F70 A;  1ZC0 A;  2WJP A;  4NWF A;  1PTU A;  5GTJ A;  1M3G A;  1PTY A;  1YTN A;  1W78 A;  1C85 A;  1WAX A;  1OEU A;  1U24 A;  5M43 A;  1Q6S A;  4HJQ A;  2CM8 A;  4DGX A;  4GFV A;  3ZM0 A;  1NWL A;  2CJZ A;  4ZRT A; 
#chains in the Genus database with same CATH homology
 1A5Y A;  2F6V A;  1PH0 A;  2H4V A;  2QBQ A;  2GP0 A;  5BUG A;  2A8B A;  1OES A;  2HVL A;  3S3F A;  2H03 A;  4KI9 A;  1U25 A;  2VEY A;  4OHH A;  4QAH A;  5K9W A;  1XM2 A;  3I80 A;  3AWE A;  2PBN A;  3BLU A;  3QCH A;  4ZI4 A;  4GFU A;  1Q6P A;  3V0E A;  1NL9 A;  1KAV A;  4QUN A;  3D44 A;  1L8K A;  3QCM A;  5EHR A;  3ZV2 A;  2CFV A;  2OZ5 A;  3ZMP A;  2I6I A;  2JJD A;  1ZZW A;  1PYN A;  2H4K A;  2PI7 A;  2F6T A;  2ZMM A;  4RKK A;  2Q05 A;  2R0B A;  3S3K A;  2P4D A;  5HDE A;  3LJ8 A;  2F6Z A;  1C83 A;  4ERC A;  1PA1 A;  4RH5 A;  5KA7 A;  5KAC A;  2NT2 A;  1YPT A;  3S3H A;  1VHR A;  2VEX A;  2BZL A;  2GJT A;  5EHP A;  3RGQ A;  1EEO A;  1YN9 A;  1ONZ A;  4BPC A;  3MOZ A;  1OEM X;  1FQ1 A;  3S3E A;  3QCF A;  5AWX A;  5KA8 A;  2FJN A;  3U96 A;  3H2X A;  2B3O A;  2YDU A;  3SME A;  4H34 A;  3S4E A;  2CNF A;  5LXQ B;  2DXP A;  1D5R A;  4R30 A;  2MBC A;  2NV5 A;  5IBM A;  2HNP A;  4TVV A;  1KAK A;  3QCC A;  2H4G A;  2QCT A;  2B49 A;  2HB1 A;  2I3U A;  2HC1 A;  3QCD A;  2NLK A;  5KAD A;  4ICZ A;  3O5X A;  1OET A;  1Q1M A;  2C46 A;  1C86 A;  4OHE A;  3D1Q A;  2BIJ A;  5BZX A;  2A3K A;  2B4O A;  1T4J A;  2J16 A;  3GXG A;  4R0S A;  2VEV A;  3CWE A;  4ZN5 A;  1JF7 A;  3O4S A;  2F6F A;  3V0I A;  4QBW A;  2I6O A;  1ONY A;  4GE5 A;  4D3Q A;  3BRH A;  3F41 A;  4WOH A;  3BM8 A;  4HJP A;  2NTA A;  4GRY A;  3AWG A;  2C7S A;  1RXD A;  2CM3 A;  1WCH A;  3MMJ A;  2WGP A;  3QCJ A;  1OEV A;  3QKQ A;  3QCE A;  3RGO A;  2B4P A;  1G7F A;  3AWF A;  3EB1 A;  5MMZ B;  4OHL A;  3BLT A;  4D3R A;  4GWF A;  2HXP A;  3S4O A;  3GXH A;  4Y14 A;  4BJO A;  1GWZ A;  2PQ5 A;  3D1O A;  4KYR A;  1I57 A;  1PTV A;  3O4U A;  2P6X A;  3OMH A;  2FJM A;  1U26 A;  4PVG A;  4QBE A;  3I7Z A;  2PSZ A;  1LAR A;  1I9S A;  2BV5 A;  1C87 A;  2CMC A;  2CNE A;  2PA5 A;  1Q6T A;  4OHI A;  1YWF A;  3D9C A;  4JBC A;  2HC2 A;  2Y96 A;  1Q6N A;  1OHE A;  3QCI A;  4QUM A;  3N0A A;  3F81 A;  3RO1 A;  4JMJ A;  5K25 A;  5BX1 A;  1QXK A;  2QDM A;  1L8G A;  2VEU A;  3M4U A;  3QCN A;  1C84 A;  4MBB A;  3F9A A;  2B07 A;  2B4S A;  2I5X A;  5KA4 A;  4YAA A;  1P15 A;  3V0F A;  1OHC A;  2J17 A;  1PA9 A;  2QDC A;  2OC3 A;  4KYQ A;  2AZR A;  2I4E A;  5J8R A;  2F6W A;  4S0G A;  1LQF A;  1WRM A;  2E0T A;  2QBR A;  2I6M A;  3ZM2 A;  3QCG A;  2F46 A;  1G4W R;  3A5K A;  1JLN A;  2G6Z A;  1MKP A;  1YZ4 A;  4WU2 A;  1YTS A;  1NNY A;  2I4G A;  2FH7 A;  2G59 A;  1AAX A;  3F9B A;  4RH9 A;  4RI5 A;  2NT7 A;  1I9T A;  4NND A;  5K9V A;  5KA3 A;  1LYV A;  2CNH A;  4NWG A;  2ZN7 A;  2I4H A;  3PS5 A;  1T49 A;  4QAP A;  2HNQ A;  2SHP A;  3QKP A;  3I36 A;  4WU3 A;  1G1H A;  5K23 A;  1XBO A;  4PYH A;  4RDD A;  4D3P A;  3V0G A;  1J4X A;  1Q6M A;  5KAB A;  2CNG A;  5KA1 A;  5KA0 A;  2QEP A;  3QCK A;  4JNB A;  3V0H A;  2J16 B;  2ESB A;  3EZZ A;  2BGD A;  1T48 A;  2M3V A;  3OLR A;  4NX8 A;  3NME A;  2B4U A;  3ZMQ A;  1G4U S;  2H04 A;  1SUG A;  1X24 A;  4GE2 A;  5BZZ A;  4YR8 B;  1GFY A;  4NYH A;  2AHS A;  3CM3 A;  1G7G A;  1V3A A;  4JMK A;  1ECV A;  2F71 A;  4GRZ A;  1ZCL A;  4GE6 A;  4R0T A;  1FPZ A;  1XXP A;  2HCM A;  1Q6J A;  4Y2E A;  3O4T A;  1BZC A;  3MOW A;  4RHG A;  3ZM1 A;  2QBP A;  2OOQ A;  3A5J A;  3F99 A;  4H1O A;  4RI4 A;  2I42 A;  2CMA A;  2QCJ A;  2CM2 A;  1BZH A;  1PTT A;  1OHD A;  3RZ2 A;  1OEO X;  4B04 A;  1YGR A;  2I6P A;  1EEN A;  4J51 A;  5KA9 A;  3EAX A;  5IBS A;  3QCB A;  2GWO A;  3SR9 A;  2I1Y A;  2CNI A;  1BZJ A;  4AZ1 A;  1R6H A;  2PT0 A;  5KAA A;  1FPR A;  1NZ7 A;  1ZCK A;  3B7O A;  4DGP A;  5KA2 A;  1XRI A;  2Y2F A;  2I75 A;  2Q47 A;  2CMB A;  4WTY A;  3O3L A;  5K22 A;  2HY3 A;  3EU0 A;  2QDP A;  2RF6 A;  3EMU A;  4HRF A;  4Z6B A;  3QCL A;  2I3R A;  3D42 A;  1YTW A;  4OHD A;  5I6V A;  5K24 A;  2I6J A;  2F6Y A;  3V0J A;  1NWE A;  2QBS A;  3V0D A;  2H02 A;  4GS0 A;  3D1H A;  1XXV A;  3ZM3 A;  2VEW A;  1YFO A;  1NO6 A;  2NZ6 A;  1RPM A;  2OUD A;  1PXH A;  1G1F A;  1C88 A;  4IKC A;  2CM7 A;  1YGU A;  2BGE A;  2IMG A;  4I8N A;  1QZ0 A;  1G1G A;  2F70 A;  1ZC0 A;  4NWF A;  1PTU A;  5GTJ A;  1M3G A;  1PTY A;  1YTN A;  1C85 A;  1WAX A;  1OEU A;  1U24 A;  5M43 A;  1Q6S A;  4HJQ A;  2CM8 A;  4DGX A;  4GFV A;  3ZM0 A;  1NWL A;  2CJZ A;  4ZRT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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