3QCGA

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
299
structure length
286
Chain Sequence
MEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase gamma
total genus 94
structure length 286
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3qcgA00
2SHPA 1C87A 4OHDA 1KAVA 3ZMQA 3V0HA 5AWXA 2VEWA 4JNBA 4ICZA 2QDCA 1G1HA 1PTVA 3QCDA 4GWFA 5KA8A 3V0IA 3OMHA 2CM8A 2QDMA 4NNDA 1YPTA 5KABA 1PXHA 3A5JA 1SUGA 1BZCA 1X24A 3NMEA 1M3GA 3QCKA 1OHDA 2H03A 5IBSA 1PA1A 4QUNA 3I80A 2P4DA 1AAXA 4RI5A 5KA4A 1A5YA 4RHGA 1NO6A 2BGDA 2FJNA 4NYHA 5KA3A 2BV5A 2H04A 4GFUA 4QBEA 4WTYA 4J51A 4RH9A 3EU0A 2PI7A 1C83A 1PTTA 1ECVA 3CM3A 4KYQA 3S4EA 1YWFA 1G7GA 1ZCLA 4RH5A 1ZZWA 5IBMA 3SMEA 4YR8B 1NZ7A 1Q6JA 2I42A 2P6XA 4HJQA 2VEVA 5I6VA 2HXPA 2I3UA 1Q1MA 2FJMA 3MMJA 1G4WR 2ESBA 2PA5A 2R0BA 2OC3A 1LYVA 2F6FA 1PA9A 1XM2A 5KA2A 3QCBA 2JJDA 1VHRA 1WAXA 2ZN7A 1Q6SA 5KA9A 3MOWA 5HDEA 4WU2A 5KAAA 2E0TA 2CMBA 2F46A 2HCMA 4GFVA 4WU3A 4PYHA 4GRZA 3S3KA 1PTYA 5M43A 2GWOA 3O3LA 3H2XA 3V0FA 4NWGA 1C84A 1L8GA 5KA7A 3QKQA 2VEXA 2NLKA 1OEUA 1Q6TA 2M3VA 3BLUA 3QCFA 3S3FA 2MBCA 2B4UA 1GFYA 1ZCKA 3F41A 1OHEA 2CMCA 4Y14A 2IMGA 1JF7A 3BM8A 1XBOA 3QKPA 3V0DA 1T49A 5KADA 4KYRA 2NT7A 2QBRA 5BZZA 2G6ZA 3EMUA 3F9AA 3B7OA 4QAPA 2CM7A 3RZ2A 1OETA 2H4GA 3GXHA 1Q6NA 1YTWA 5KACA 2NZ6A 1LARA 3ZMPA 2CNGA 5K24A 4GE5A 5GTJA 2Q05A 3RO1A 5EHRA 2I6IA 2I4GA 4I8NA 2Q47A 3MOZA 3CWEA 3QCEA 2QEPA 1I9TA 2GJTA 1OHCA 2PBNA 2G59A 4AZ1A 4OHHA 2F6TA 2OZ5A 2NT2A 4TVVA 2HNPA 2HVLA 3O5XA 5K9VA 1G1GA 2ZMMA 5KA0A 2CNHA 1OEVA 1FQ1A 1I57A 1BZHA 4GRYA 2OOQA 3ZM1A 4BPCA 2RF6A 2F6VA 2J16A 4JBCA 2HB1A 5K9WA 2B49A 1PYNA 3D1OA 1G7FA 1U25A 3AWFA 1EEOA 2A8BA 4BJOA 2C46A 4S0GA 2QCTA 1U24A 2I6PA 3QCLA 1RPMA 1YGUA 3O4UA 1QZ0A 1P15A 1Q6MA 2NTAA 2HC2A 3M4UA 4B04A 4WOHA 4D3QA 5LXQB 4Z6BA 3LJ8A 2F6ZA 4MBBA 2I4EA 1NNYA 2AZRA 3AWGA 2F6YA 2CNEA 4RDDA 2QCJA 5EHPA 1LQFA 1OESA 1YN9A 3I7ZA 3S3HA 4R0SA 3D1HA 4DGXA 3F99A 2CM2A 2PT0A 1BZJA 1FPZA 2DXPA 1ONYA 5K23A 4ZI4A 4HRFA 1T48A 4GS0A 5J8RA 1U26A 3RGOA 3QCIA 2F71A 2WGPA 2I1YA 4GE6A 4D3PA 1OEMX 5K22A 2I6OA 2VEUA 4OHIA 1T4JA 1KAKA 4OHLA 3QCMA 2BGEA 4RKKA 3D42A 3ZM0A 2C7SA 2CM3A 2Y2FA 2CFVA 1C86A 2FH7A 2I6MA 2AHSA 2CNFA 2B07A 3V0EA 1D5RA 4HJPA 2F70A 2QDPA 3GXGA 1C85A 1I9SA 2CMAA 4NWFA 2I6JA 3ZV2A 4JMKA 3EZZA 4D3RA 4ERCA 4DGPA 2F6WA 4GE2A 2B4OA 4QAHA 4H34A 1G1FA 2PQ5A 3S3EA 2QBQA 3QCHA 4QUMA 3F81A 2HNQA 3ZM2A 3V0JA 5BX1A 4YAAA 1YTSA 1PH0A 3I36A 4NX8A 3OLRA 1WCHA 3QCNA 2QBPA 3S4OA 1ZC0A 1QXKA 5K25A 4JMJA 2H02A 3BRHA 3N0AA 1J4XA 4R0TA 2J16B 3F9BA 1JLNA 3U96A 1RXDA 1MKPA 1XXPA 2I3RA 1V3AA 1YZ4A 5BZXA 1R6HA 4ZRTA 3O4TA 3A5KA 4KI9A 2B4SA 4IKCA 2YDUA 1YFOA 3AWEA 1Q6PA 3D9CA 4ZN5A 3O4SA 1PTUA 2I75A 1NL9A 3BLTA 2B4PA 4PVGA 2CNIA 2OUDA 3D1QA 1L8KA 3PS5A 4QBWA 3QCCA 2I5XA 2VEYA 1ONZA 3EAXA 2H4VA 1C88A 2H4KA 3V0GA 1FPRA 3SR9A 1WRMA 2A3KA 1G4US 1GWZA 2B3OA 1EENA 4R30A 2BZLA 4OHEA 3EB1A 2BIJA 2HC1A 3QCJA 2GP0A 2PSZA 3ZM3A 4H1OA 1XRIA 1OEOX 1YTNA 5MMZB 2QBSA 2HY3A 5KA1A 3D44A 2I4HA 1NWLA 1NWEA 2Y96A 2J17A 3QCGA 1XXVA 1YGRA 2CJZA 3RGQA 2NV5A 5BUGA 4RI4A 4Y2EA
chains in the Genus database with same CATH superfamily
2JFGA 1E0DA 2SHPA 2AM1A 1C87A 3HN7A 4OHDA 4HV4A 1KAVA 3ZMQA 3V0HA 5AWXA 2VEWA 4JNBA 4ICZA 2QDCA 1G1HA 1PTVA 3QCDA 4GWFA 5KA8A 3V0IA 2Y1OA 3OMHA 2CM8A 2QDMA 4NNDA 1YPTA 5KABA 1PXHA 2Y68A 3A5JA 1SUGA 1BZCA 1X24A 3NMEA 1M3GA 3QCKA 4CVMA 1OHDA 2H03A 5IBSA 2GCAA 1PA1A 4QUNA 3I80A 2P4DA 1AAXA 4RI5A 2GC6A 5KA4A 1A5YA 4RHGA 1NO6A 2BGDA 2FJNA 4NYHA 5KA3A 2GCBA 4QDIA 2BV5A 2H04A 4GFUA 1FGSA 2VORA 4QBEA 4WTYA 4J51A 4RH9A 3EU0A 2PI7A 1C83A 1PTTA 2Y66A 1ECVA 3CM3A 4KYQA 3S4EA 1YWFA 1G7GA 1ZCLA 4RH5A 5A5FA 1ZZWA 5IBMA 3SMEA 4YR8B 1NZ7A 1Q6JA 2I42A 2P6XA 4HJQA 2VEVA 5I6VA 2HXPA 2I3UA 1Q1MA 2FJMA 3MMJA 2VOSA 1G4WR 3NRSA 2ESBA 2PA5A 2R0BA 2OC3A 1LYVA 2F6FA 1PA9A 1XM2A 5KA2A 3QCBA 2JJDA 1VHRA 1WAXA 2ZN7A 1Q6SA 5KA9A 3MOWA 5HDEA 4WU2A 5KAAA 2E0TA 2CMBA 2F46A 2HCMA 4GFVA 4WU3A 4PYHA 4GRZA 3S3KA 1O5ZA 1PTYA 5M43A 2GWOA 3O3LA 3H2XA 3V0FA 4NWGA 1C84A 1L8GA 4QF5A 5KA7A 3QKQA 2VEXA 2NLKA 1OEUA 1Q6TA 2M3VA 3BLUA 3QCFA 3S3FA 2MBCA 2B4UA 1GFYA 1ZCKA 3F41A 1OHEA 2CMCA 4Y14A 2IMGA 1JF7A 2VTEA 3BM8A 1XBOA 3QKPA 3V0DA 1T49A 2JFHA 4KYRA 5KADA 2NT7A 2QBRA 5BZZA 2G6ZA 3EMUA 3F9AA 3B7OA 4QAPA 2CM7A 3RZ2A 1OETA 1EEHA 2H4GA 3GXHA 1Q6NA 1YTWA 5KACA 2NZ6A 1LARA 3ZMPA 2CNGA 5K24A 4GE5A 5GTJA 2Q05A 3RO1A 5EHRA 3ZL8A 2I6IA 2I4GA 4I8NA 4UAGA 4CVLA 2Q47A 2Y67A 3MOZA 3CWEA 3QCEA 2QEPA 1I9TA 2GJTA 1OHCA 2PBNA 2G59A 4AZ1A 4OHHA 2F6TA 2OZ5A 2NT2A 4TVVA 2HNPA 2HVLA 3O5XA 5K9VA 1G1GA 2ZMMA 5KA0A 2CNHA 1OEVA 1FQ1A 1I57A 1BZHA 4GRYA 2OOQA 3ZM1A 4BPCA 2RF6A 2F6VA 2J16A 4JBCA 4CVKA 2HB1A 2XJAA 5K9WA 2UAGA 2B49A 1PYNA 3D1OA 1G7FA 1U25A 3AWFA 1EEOA 2A8BA 2UUPA 4BJOA 2C46A 4S0GA 2QCTA 1U24A 2I6PA 4C12A 3QCLA 1RPMA 1YGUA 3N2AA 1QZ0A 3O4UA 1P15A 1Q6MA 2NTAA 2HC2A 3M4UA 2F00A 4B04A 4WOHA 4D3QA 5LXQB 4Z6BA 2WJPA 3LJ8A 2F6ZA 4MBBA 1W7KA 2I4EA 1NNYA 2AZRA 3AWGA 2F6YA 2CNEA 4RDDA 2QCJA 5EHPA 1LQFA 1OESA 1YN9A 3I7ZA 3S3HA 4R0SA 3D1HA 4DGXA 2AM2A 3ZM6A 3F99A 2CM2A 2PT0A 1BZJA 1GQYA 1FPZA 2DXPA 2UUOA 2JFFA 1ONYA 5K23A 4ZI4A 4HRFA 1T48A 4GS0A 5J8RA 1U26A 3PYZA 3RGOA 4BUCA 1P31A 3QCIA 2F71A 2WGPA 1GQQA 2I1YA 4GE6A 4D3PA 1OEMX 5K22A 2I6OA 2VEUA 4OHIA 1T4JA 1KAKA 4OHLA 3QCMA 2BGEA 3LK7A 4RKKA 3D42A 3ZM0A 1GG4A 2C7SA 2CM3A 2VTDA 2Y2FA 2CFVA 1C86A 2FH7A 2I6MA 2AHSA 2CNFA 2B07A 3V0EA 1D5RA 4HJPA 2F70A 2QDPA 3UAGA 3GXGA 1C85A 5A5EA 1I9SA 2CMAA 4NWFA 1J6UA 2XPCA 2WTZA 2I6JA 3ZV2A 4JMKA 3EZZA 3QCZA 4D3RA 4ERCA 4DGPA 1JBVA 2F6WA 4GE2A 2B4OA 4QAHA 4H34A 1G1FA 2PQ5A 3S3EA 2QBQA 3QCHA 2GC5A 4QUMA 1JBWA 3F81A 2HNQA 3ZM2A 4ZIYA 3V0JA 5BX1A 4YAAA 1YTSA 1PH0A 3I36A 4NX8A 1P3DA 3OLRA 1WCHA 3QCNA 2QBPA 3S4OA 1ZC0A 1QXKA 5K25A 4JMJA 2H02A 3BRHA 3N0AA 1J4XA 4R0TA 2J16B 3F9BA 1JLNA 3U96A 1RXDA 1MKPA 1XXPA 2I3RA 1V3AA 1YZ4A 5BZXA 1R6HA 3MVNA 4ZRTA 3O4TA 3A5KA 4KI9A 2B4SA 4IKCA 2YDUA 1YFOA 3AWEA 1Q6PA 3D9CA 4ZN5A 3O4SA 1PTUA 3ZM5A 1W78A 1E8CA 2I75A 1NL9A 3BLTA 2B4PA 4PVGA 2CNIA 2OUDA 2X5OA 3D1QA 1L8KA 3PS5A 4QBWA 3QCCA 2I5XA 2VEYA 1ONZA 3EAXA 2H4VA 1C88A 2H4KA 3V0GA 1FPRA 3SR9A 1WRMA 2A3KA 1G4US 1GWZA 2B3OA 1EENA 4R30A 2BZLA 4OHEA 3EB1A 2BIJA 2HC1A 4BUBA 3QCJA 2GP0A 2PSZA 3ZM3A 4H1OA 1XRIA 1OEOX 1YTNA 5MMZB 2QBSA 2HY3A 5KA1A 3D44A 2I4HA 1NWLA 1NWEA 2Y96A 2J17A 3QCGA 1XXVA 1YGRA 2CJZA 4C13A 1UAGA 3RGQA 2NV5A 5BUGA 4RI4A 4Y2EA
chains in the Genus database with same CATH topology
2SHPA 1C87A 4OHDA 1KAVA 3ZMQA 3V0HA 5AWXA 2VEWA 4JNBA 4ICZA 2QDCA 1G1HA 1PTVA 3QCDA 4GWFA 5KA8A 3V0IA 3OMHA 2CM8A 2QDMA 4NNDA 1YPTA 5KABA 1PXHA 3A5JA 1SUGA 1BZCA 1X24A 3NMEA 1M3GA 3QCKA 1OHDA 2H03A 5IBSA 1PA1A 4QUNA 3I80A 2P4DA 1AAXA 4RI5A 5KA4A 1A5YA 4RHGA 1NO6A 2BGDA 2FJNA 4NYHA 5KA3A 2BV5A 2H04A 4GFUA 4QBEA 4WTYA 4J51A 4RH9A 3EU0A 2PI7A 1C83A 1PTTA 1ECVA 3CM3A 4KYQA 3S4EA 1YWFA 1G7GA 1ZCLA 4RH5A 1ZZWA 5IBMA 3SMEA 4YR8B 1NZ7A 1Q6JA 2I42A 2P6XA 4HJQA 2VEVA 5I6VA 2HXPA 2I3UA 1Q1MA 2FJMA 3MMJA 1G4WR 2ESBA 2PA5A 2R0BA 2OC3A 1LYVA 2F6FA 1PA9A 1XM2A 5KA2A 3QCBA 2JJDA 1VHRA 1WAXA 2ZN7A 1Q6SA 5KA9A 3MOWA 5HDEA 4WU2A 5KAAA 2E0TA 2CMBA 2F46A 2HCMA 4GFVA 4WU3A 4PYHA 4GRZA 3S3KA 1PTYA 5M43A 2GWOA 3O3LA 3H2XA 3V0FA 4NWGA 1C84A 1L8GA 5KA7A 3QKQA 2VEXA 2NLKA 1OEUA 1Q6TA 2M3VA 3BLUA 3QCFA 3S3FA 2MBCA 2B4UA 1GFYA 1ZCKA 3F41A 1OHEA 2CMCA 4Y14A 2IMGA 1JF7A 3BM8A 1XBOA 3QKPA 3V0DA 1T49A 5KADA 4KYRA 2NT7A 2QBRA 5BZZA 2G6ZA 3EMUA 3F9AA 3B7OA 4QAPA 2CM7A 3RZ2A 1OETA 2H4GA 3GXHA 1Q6NA 1YTWA 5KACA 2NZ6A 1LARA 3ZMPA 2CNGA 5K24A 4GE5A 5GTJA 2Q05A 3RO1A 5EHRA 2I6IA 2I4GA 4I8NA 2Q47A 3MOZA 3CWEA 3QCEA 2QEPA 1I9TA 2GJTA 1OHCA 2PBNA 2G59A 4AZ1A 4OHHA 2F6TA 2OZ5A 2NT2A 4TVVA 2HNPA 2HVLA 3O5XA 5K9VA 1G1GA 2ZMMA 5KA0A 2CNHA 1OEVA 1FQ1A 1I57A 1BZHA 4GRYA 2OOQA 3ZM1A 4BPCA 2RF6A 2F6VA 2J16A 4JBCA 2HB1A 5K9WA 2B49A 1PYNA 3D1OA 1G7FA 1U25A 3AWFA 1EEOA 2A8BA 4BJOA 2C46A 4S0GA 2QCTA 1U24A 2I6PA 3QCLA 1RPMA 1YGUA 3O4UA 1QZ0A 1P15A 1Q6MA 2NTAA 2HC2A 3M4UA 4B04A 4WOHA 4D3QA 5LXQB 4Z6BA 3LJ8A 2F6ZA 4MBBA 2I4EA 1NNYA 2AZRA 3AWGA 2F6YA 2CNEA 4RDDA 2QCJA 5EHPA 1LQFA 1OESA 1YN9A 3I7ZA 3S3HA 4R0SA 3D1HA 4DGXA 3F99A 2CM2A 2PT0A 1BZJA 1FPZA 2DXPA 1ONYA 5K23A 4ZI4A 4HRFA 1T48A 4GS0A 5J8RA 1U26A 3RGOA 3QCIA 2F71A 2WGPA 2I1YA 4GE6A 4D3PA 1OEMX 5K22A 2I6OA 2VEUA 4OHIA 1T4JA 1KAKA 4OHLA 3QCMA 2BGEA 4RKKA 3D42A 3ZM0A 2C7SA 2CM3A 2Y2FA 2CFVA 1C86A 2FH7A 2I6MA 2AHSA 2CNFA 2B07A 3V0EA 1D5RA 4HJPA 2F70A 2QDPA 3GXGA 1C85A 1I9SA 2CMAA 4NWFA 2I6JA 3ZV2A 4JMKA 3EZZA 4D3RA 4ERCA 4DGPA 2F6WA 4GE2A 2B4OA 4QAHA 4H34A 1G1FA 2PQ5A 3S3EA 2QBQA 3QCHA 4QUMA 3F81A 2HNQA 3ZM2A 3V0JA 5BX1A 4YAAA 1YTSA 1PH0A 3I36A 4NX8A 3OLRA 1WCHA 3QCNA 2QBPA 3S4OA 1ZC0A 1QXKA 5K25A 4JMJA 2H02A 3BRHA 3N0AA 1J4XA 4R0TA 2J16B 3F9BA 1JLNA 3U96A 1RXDA 1MKPA 1XXPA 2I3RA 1V3AA 1YZ4A 5BZXA 1R6HA 4ZRTA 3O4TA 3A5KA 4KI9A 2B4SA 4IKCA 2YDUA 1YFOA 3AWEA 1Q6PA 3D9CA 4ZN5A 3O4SA 1PTUA 2I75A 1NL9A 3BLTA 2B4PA 4PVGA 2CNIA 2OUDA 3D1QA 1L8KA 3PS5A 4QBWA 3QCCA 2I5XA 2VEYA 1ONZA 3EAXA 2H4VA 1C88A 2H4KA 3V0GA 1FPRA 3SR9A 1WRMA 2A3KA 1G4US 1GWZA 2B3OA 1EENA 4R30A 2BZLA 4OHEA 3EB1A 2BIJA 2HC1A 3QCJA 2GP0A 2PSZA 3ZM3A 4H1OA 1XRIA 1OEOX 1YTNA 5MMZB 2QBSA 2HY3A 5KA1A 3D44A 2I4HA 1NWLA 1NWEA 2Y96A 2J17A 3QCGA 1XXVA 1YGRA 2CJZA 3RGQA 2NV5A 5BUGA 4RI4A 4Y2EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SHP A;  1C87 A;  4OHD A;  1KAV A;  3ZMQ A;  3V0H A;  5AWX A;  2VEW A;  4JNB A;  4ICZ A;  2QDC A;  1G1H A;  1PTV A;  3QCD A;  4GWF A;  5KA8 A;  3V0I A;  3OMH A;  2CM8 A;  2QDM A;  4NND A;  1YPT A;  5KAB A;  1PXH A;  3A5J A;  1SUG A;  1BZC A;  1X24 A;  3NME A;  1M3G A;  3QCK A;  1OHD A;  2H03 A;  5IBS A;  1PA1 A;  4QUN A;  3I80 A;  2P4D A;  1AAX A;  4RI5 A;  5KA4 A;  1A5Y A;  4RHG A;  1NO6 A;  2BGD A;  2FJN A;  4NYH A;  5KA3 A;  2BV5 A;  2H04 A;  4GFU A;  4QBE A;  4WTY A;  4J51 A;  4RH9 A;  3EU0 A;  2PI7 A;  1C83 A;  1PTT A;  1ECV A;  3CM3 A;  4KYQ A;  3S4E A;  1YWF A;  1G7G A;  1ZCL A;  4RH5 A;  1ZZW A;  5IBM A;  3SME A;  4YR8 B;  1NZ7 A;  1Q6J A;  2I42 A;  2P6X A;  4HJQ A;  2VEV A;  5I6V A;  2HXP A;  2I3U A;  1Q1M A;  2FJM A;  3MMJ A;  1G4W R;  2ESB A;  2PA5 A;  2R0B A;  2OC3 A;  1LYV A;  2F6F A;  1PA9 A;  1XM2 A;  5KA2 A;  3QCB A;  2JJD A;  1VHR A;  1WAX A;  2ZN7 A;  1Q6S A;  5KA9 A;  3MOW A;  5HDE A;  4WU2 A;  5KAA A;  2E0T A;  2CMB A;  2F46 A;  2HCM A;  4GFV A;  4WU3 A;  4PYH A;  4GRZ A;  3S3K A;  1PTY A;  5M43 A;  2GWO A;  3O3L A;  3H2X A;  3V0F A;  4NWG A;  1C84 A;  1L8G A;  5KA7 A;  3QKQ A;  2VEX A;  2NLK A;  1OEU A;  1Q6T A;  2M3V A;  3BLU A;  3QCF A;  3S3F A;  2MBC A;  2B4U A;  1GFY A;  1ZCK A;  3F41 A;  1OHE A;  2CMC A;  4Y14 A;  2IMG A;  1JF7 A;  3BM8 A;  1XBO A;  3QKP A;  3V0D A;  1T49 A;  5KAD A;  4KYR A;  2NT7 A;  2QBR A;  5BZZ A;  2G6Z A;  3EMU A;  3F9A A;  3B7O A;  4QAP A;  2CM7 A;  3RZ2 A;  1OET A;  2H4G A;  3GXH A;  1Q6N A;  1YTW A;  5KAC A;  2NZ6 A;  1LAR A;  3ZMP A;  2CNG A;  5K24 A;  4GE5 A;  5GTJ A;  2Q05 A;  3RO1 A;  5EHR A;  2I6I A;  2I4G A;  4I8N A;  2Q47 A;  3MOZ A;  3CWE A;  3QCE A;  2QEP A;  1I9T A;  2GJT A;  1OHC A;  2PBN A;  2G59 A;  4AZ1 A;  4OHH A;  2F6T A;  2OZ5 A;  2NT2 A;  4TVV A;  2HNP A;  2HVL A;  3O5X A;  5K9V A;  1G1G A;  2ZMM A;  5KA0 A;  2CNH A;  1OEV A;  1FQ1 A;  1I57 A;  1BZH A;  4GRY A;  2OOQ A;  3ZM1 A;  4BPC A;  2RF6 A;  2F6V A;  2J16 A;  4JBC A;  2HB1 A;  5K9W A;  2B49 A;  1PYN A;  3D1O A;  1G7F A;  1U25 A;  3AWF A;  1EEO A;  2A8B A;  4BJO A;  2C46 A;  4S0G A;  2QCT A;  1U24 A;  2I6P A;  3QCL A;  1RPM A;  1YGU A;  3O4U A;  1QZ0 A;  1P15 A;  1Q6M A;  2NTA A;  2HC2 A;  3M4U A;  4B04 A;  4WOH A;  4D3Q A;  5LXQ B;  4Z6B A;  3LJ8 A;  2F6Z A;  4MBB A;  2I4E A;  1NNY A;  2AZR A;  3AWG A;  2F6Y A;  2CNE A;  4RDD A;  2QCJ A;  5EHP A;  1LQF A;  1OES A;  1YN9 A;  3I7Z A;  3S3H A;  4R0S A;  3D1H A;  4DGX A;  3F99 A;  2CM2 A;  2PT0 A;  1BZJ A;  1FPZ A;  2DXP A;  1ONY A;  5K23 A;  4ZI4 A;  4HRF A;  1T48 A;  4GS0 A;  5J8R A;  1U26 A;  3RGO A;  3QCI A;  2F71 A;  2WGP A;  2I1Y A;  4GE6 A;  4D3P A;  1OEM X;  5K22 A;  2I6O A;  2VEU A;  4OHI A;  1T4J A;  1KAK A;  4OHL A;  3QCM A;  2BGE A;  4RKK A;  3D42 A;  3ZM0 A;  2C7S A;  2CM3 A;  2Y2F A;  2CFV A;  1C86 A;  2FH7 A;  2I6M A;  2AHS A;  2CNF A;  2B07 A;  3V0E A;  1D5R A;  4HJP A;  2F70 A;  2QDP A;  3GXG A;  1C85 A;  1I9S A;  2CMA A;  4NWF A;  2I6J A;  3ZV2 A;  4JMK A;  3EZZ A;  4D3R A;  4ERC A;  4DGP A;  2F6W A;  4GE2 A;  2B4O A;  4QAH A;  4H34 A;  1G1F A;  2PQ5 A;  3S3E A;  2QBQ A;  3QCH A;  4QUM A;  3F81 A;  2HNQ A;  3ZM2 A;  3V0J A;  5BX1 A;  4YAA A;  1YTS A;  1PH0 A;  3I36 A;  4NX8 A;  3OLR A;  1WCH A;  3QCN A;  2QBP A;  3S4O A;  1ZC0 A;  1QXK A;  5K25 A;  4JMJ A;  2H02 A;  3BRH A;  3N0A A;  1J4X A;  4R0T A;  2J16 B;  3F9B A;  1JLN A;  3U96 A;  1RXD A;  1MKP A;  1XXP A;  2I3R A;  1V3A A;  1YZ4 A;  5BZX A;  1R6H A;  4ZRT A;  3O4T A;  3A5K A;  4KI9 A;  2B4S A;  4IKC A;  2YDU A;  1YFO A;  3AWE A;  1Q6P A;  3D9C A;  4ZN5 A;  3O4S A;  1PTU A;  2I75 A;  1NL9 A;  3BLT A;  2B4P A;  4PVG A;  2CNI A;  2OUD A;  3D1Q A;  1L8K A;  3PS5 A;  4QBW A;  3QCC A;  2I5X A;  2VEY A;  1ONZ A;  3EAX A;  2H4V A;  1C88 A;  2H4K A;  3V0G A;  1FPR A;  3SR9 A;  1WRM A;  2A3K A;  1G4U S;  1GWZ A;  2B3O A;  1EEN A;  4R30 A;  2BZL A;  4OHE A;  3EB1 A;  2BIJ A;  2HC1 A;  3QCJ A;  2GP0 A;  2PSZ A;  3ZM3 A;  4H1O A;  1XRI A;  1OEO X;  1YTN A;  5MMZ B;  2QBS A;  2HY3 A;  5KA1 A;  3D44 A;  2I4H A;  1NWL A;  1NWE A;  2Y96 A;  2J17 A;  3QCG A;  1XXV A;  1YGR A;  2CJZ A;  3RGQ A;  2NV5 A;  5BUG A;  4RI4 A;  4Y2E A; 
#chains in the Genus database with same CATH topology
 2JFG A;  1E0D A;  2SHP A;  2AM1 A;  1C87 A;  3HN7 A;  4OHD A;  4HV4 A;  1KAV A;  3ZMQ A;  3V0H A;  5AWX A;  2VEW A;  4JNB A;  4ICZ A;  2QDC A;  1G1H A;  1PTV A;  3QCD A;  4GWF A;  5KA8 A;  3V0I A;  2Y1O A;  3OMH A;  2CM8 A;  2QDM A;  4NND A;  1YPT A;  5KAB A;  1PXH A;  2Y68 A;  3A5J A;  1SUG A;  1BZC A;  1X24 A;  3NME A;  1M3G A;  3QCK A;  4CVM A;  1OHD A;  2H03 A;  5IBS A;  2GCA A;  1PA1 A;  4QUN A;  3I80 A;  2P4D A;  1AAX A;  4RI5 A;  2GC6 A;  5KA4 A;  1A5Y A;  4RHG A;  1NO6 A;  2BGD A;  2FJN A;  4NYH A;  5KA3 A;  2GCB A;  4QDI A;  2BV5 A;  2H04 A;  4GFU A;  1FGS A;  2VOR A;  4QBE A;  4WTY A;  4J51 A;  4RH9 A;  3EU0 A;  2PI7 A;  1C83 A;  1PTT A;  2Y66 A;  1ECV A;  3CM3 A;  4KYQ A;  3S4E A;  1YWF A;  1G7G A;  1ZCL A;  4RH5 A;  5A5F A;  1ZZW A;  5IBM A;  3SME A;  4YR8 B;  1NZ7 A;  1Q6J A;  2I42 A;  2P6X A;  4HJQ A;  2VEV A;  5I6V A;  2HXP A;  2I3U A;  1Q1M A;  2FJM A;  3MMJ A;  2VOS A;  1G4W R;  3NRS A;  2ESB A;  2PA5 A;  2R0B A;  2OC3 A;  1LYV A;  2F6F A;  1PA9 A;  1XM2 A;  5KA2 A;  3QCB A;  2JJD A;  1VHR A;  1WAX A;  2ZN7 A;  1Q6S A;  5KA9 A;  3MOW A;  5HDE A;  4WU2 A;  5KAA A;  2E0T A;  2CMB A;  2F46 A;  2HCM A;  4GFV A;  4WU3 A;  4PYH A;  4GRZ A;  3S3K A;  1O5Z A;  1PTY A;  5M43 A;  2GWO A;  3O3L A;  3H2X A;  3V0F A;  4NWG A;  1C84 A;  1L8G A;  4QF5 A;  5KA7 A;  3QKQ A;  2VEX A;  2NLK A;  1OEU A;  1Q6T A;  2M3V A;  3BLU A;  3QCF A;  3S3F A;  2MBC A;  2B4U A;  1GFY A;  1ZCK A;  3F41 A;  1OHE A;  2CMC A;  4Y14 A;  2IMG A;  1JF7 A;  2VTE A;  3BM8 A;  1XBO A;  3QKP A;  3V0D A;  1T49 A;  2JFH A;  4KYR A;  5KAD A;  2NT7 A;  2QBR A;  5BZZ A;  2G6Z A;  3EMU A;  3F9A A;  3B7O A;  4QAP A;  2CM7 A;  3RZ2 A;  1OET A;  1EEH A;  2H4G A;  3GXH A;  1Q6N A;  1YTW A;  5KAC A;  2NZ6 A;  1LAR A;  3ZMP A;  2CNG A;  5K24 A;  4GE5 A;  5GTJ A;  2Q05 A;  3RO1 A;  5EHR A;  3ZL8 A;  2I6I A;  2I4G A;  4I8N A;  4UAG A;  4CVL A;  2Q47 A;  2Y67 A;  3MOZ A;  3CWE A;  3QCE A;  2QEP A;  1I9T A;  2GJT A;  1OHC A;  2PBN A;  2G59 A;  4AZ1 A;  4OHH A;  2F6T A;  2OZ5 A;  2NT2 A;  4TVV A;  2HNP A;  2HVL A;  3O5X A;  5K9V A;  1G1G A;  2ZMM A;  5KA0 A;  2CNH A;  1OEV A;  1FQ1 A;  1I57 A;  1BZH A;  4GRY A;  2OOQ A;  3ZM1 A;  4BPC A;  2RF6 A;  2F6V A;  2J16 A;  4JBC A;  4CVK A;  2HB1 A;  2XJA A;  5K9W A;  2UAG A;  2B49 A;  1PYN A;  3D1O A;  1G7F A;  1U25 A;  3AWF A;  1EEO A;  2A8B A;  2UUP A;  4BJO A;  2C46 A;  4S0G A;  2QCT A;  1U24 A;  2I6P A;  4C12 A;  3QCL A;  1RPM A;  1YGU A;  3N2A A;  1QZ0 A;  3O4U A;  1P15 A;  1Q6M A;  2NTA A;  2HC2 A;  3M4U A;  2F00 A;  4B04 A;  4WOH A;  4D3Q A;  5LXQ B;  4Z6B A;  2WJP A;  3LJ8 A;  2F6Z A;  4MBB A;  1W7K A;  2I4E A;  1NNY A;  2AZR A;  3AWG A;  2F6Y A;  2CNE A;  4RDD A;  2QCJ A;  5EHP A;  1LQF A;  1OES A;  1YN9 A;  3I7Z A;  3S3H A;  4R0S A;  3D1H A;  4DGX A;  2AM2 A;  3ZM6 A;  3F99 A;  2CM2 A;  2PT0 A;  1BZJ A;  1GQY A;  1FPZ A;  2DXP A;  2UUO A;  2JFF A;  1ONY A;  5K23 A;  4ZI4 A;  4HRF A;  1T48 A;  4GS0 A;  5J8R A;  1U26 A;  3PYZ A;  3RGO A;  4BUC A;  1P31 A;  3QCI A;  2F71 A;  2WGP A;  1GQQ A;  2I1Y A;  4GE6 A;  4D3P A;  1OEM X;  5K22 A;  2I6O A;  2VEU A;  4OHI A;  1T4J A;  1KAK A;  4OHL A;  3QCM A;  2BGE A;  3LK7 A;  4RKK A;  3D42 A;  3ZM0 A;  1GG4 A;  2C7S A;  2CM3 A;  2VTD A;  2Y2F A;  2CFV A;  1C86 A;  2FH7 A;  2I6M A;  2AHS A;  2CNF A;  2B07 A;  3V0E A;  1D5R A;  4HJP A;  2F70 A;  2QDP A;  3UAG A;  3GXG A;  1C85 A;  5A5E A;  1I9S A;  2CMA A;  4NWF A;  1J6U A;  2XPC A;  2WTZ A;  2I6J A;  3ZV2 A;  4JMK A;  3EZZ A;  3QCZ A;  4D3R A;  4ERC A;  4DGP A;  1JBV A;  2F6W A;  4GE2 A;  2B4O A;  4QAH A;  4H34 A;  1G1F A;  2PQ5 A;  3S3E A;  2QBQ A;  3QCH A;  2GC5 A;  4QUM A;  1JBW A;  3F81 A;  2HNQ A;  3ZM2 A;  4ZIY A;  3V0J A;  5BX1 A;  4YAA A;  1YTS A;  1PH0 A;  3I36 A;  4NX8 A;  1P3D A;  3OLR A;  1WCH A;  3QCN A;  2QBP A;  3S4O A;  1ZC0 A;  1QXK A;  5K25 A;  4JMJ A;  2H02 A;  3BRH A;  3N0A A;  1J4X A;  4R0T A;  2J16 B;  3F9B A;  1JLN A;  3U96 A;  1RXD A;  1MKP A;  1XXP A;  2I3R A;  1V3A A;  1YZ4 A;  5BZX A;  1R6H A;  3MVN A;  4ZRT A;  3O4T A;  3A5K A;  4KI9 A;  2B4S A;  4IKC A;  2YDU A;  1YFO A;  3AWE A;  1Q6P A;  3D9C A;  4ZN5 A;  3O4S A;  1PTU A;  3ZM5 A;  1W78 A;  1E8C A;  2I75 A;  1NL9 A;  3BLT A;  2B4P A;  4PVG A;  2CNI A;  2OUD A;  2X5O A;  3D1Q A;  1L8K A;  3PS5 A;  4QBW A;  3QCC A;  2I5X A;  2VEY A;  1ONZ A;  3EAX A;  2H4V A;  1C88 A;  2H4K A;  3V0G A;  1FPR A;  3SR9 A;  1WRM A;  2A3K A;  1G4U S;  1GWZ A;  2B3O A;  1EEN A;  4R30 A;  2BZL A;  4OHE A;  3EB1 A;  2BIJ A;  2HC1 A;  4BUB A;  3QCJ A;  2GP0 A;  2PSZ A;  3ZM3 A;  4H1O A;  1XRI A;  1OEO X;  1YTN A;  5MMZ B;  2QBS A;  2HY3 A;  5KA1 A;  3D44 A;  2I4H A;  1NWL A;  1NWE A;  2Y96 A;  2J17 A;  3QCG A;  1XXV A;  1YGR A;  2CJZ A;  4C13 A;  1UAG A;  3RGQ A;  2NV5 A;  5BUG A;  4RI4 A;  4Y2E A; 
#chains in the Genus database with same CATH homology
 2SHP A;  1C87 A;  4OHD A;  1KAV A;  3ZMQ A;  3V0H A;  5AWX A;  2VEW A;  4JNB A;  4ICZ A;  2QDC A;  1G1H A;  1PTV A;  3QCD A;  4GWF A;  5KA8 A;  3V0I A;  3OMH A;  2CM8 A;  2QDM A;  4NND A;  1YPT A;  5KAB A;  1PXH A;  3A5J A;  1SUG A;  1BZC A;  1X24 A;  3NME A;  1M3G A;  3QCK A;  1OHD A;  2H03 A;  5IBS A;  1PA1 A;  4QUN A;  3I80 A;  2P4D A;  1AAX A;  4RI5 A;  5KA4 A;  1A5Y A;  4RHG A;  1NO6 A;  2BGD A;  2FJN A;  4NYH A;  5KA3 A;  2BV5 A;  2H04 A;  4GFU A;  4QBE A;  4WTY A;  4J51 A;  4RH9 A;  3EU0 A;  2PI7 A;  1C83 A;  1PTT A;  1ECV A;  3CM3 A;  4KYQ A;  3S4E A;  1YWF A;  1G7G A;  1ZCL A;  4RH5 A;  1ZZW A;  5IBM A;  3SME A;  4YR8 B;  1NZ7 A;  1Q6J A;  2I42 A;  2P6X A;  4HJQ A;  2VEV A;  5I6V A;  2HXP A;  2I3U A;  1Q1M A;  2FJM A;  3MMJ A;  1G4W R;  2ESB A;  2PA5 A;  2R0B A;  2OC3 A;  1LYV A;  2F6F A;  1PA9 A;  1XM2 A;  5KA2 A;  3QCB A;  2JJD A;  1VHR A;  1WAX A;  2ZN7 A;  1Q6S A;  5KA9 A;  3MOW A;  5HDE A;  4WU2 A;  5KAA A;  2E0T A;  2CMB A;  2F46 A;  2HCM A;  4GFV A;  4WU3 A;  4PYH A;  4GRZ A;  3S3K A;  1PTY A;  5M43 A;  2GWO A;  3O3L A;  3H2X A;  3V0F A;  4NWG A;  1C84 A;  1L8G A;  5KA7 A;  3QKQ A;  2VEX A;  2NLK A;  1OEU A;  1Q6T A;  2M3V A;  3BLU A;  3QCF A;  3S3F A;  2MBC A;  2B4U A;  1GFY A;  1ZCK A;  3F41 A;  1OHE A;  2CMC A;  4Y14 A;  2IMG A;  1JF7 A;  3BM8 A;  1XBO A;  3QKP A;  3V0D A;  1T49 A;  5KAD A;  4KYR A;  2NT7 A;  2QBR A;  5BZZ A;  2G6Z A;  3EMU A;  3F9A A;  3B7O A;  4QAP A;  2CM7 A;  3RZ2 A;  1OET A;  2H4G A;  3GXH A;  1Q6N A;  1YTW A;  5KAC A;  2NZ6 A;  1LAR A;  3ZMP A;  2CNG A;  5K24 A;  4GE5 A;  5GTJ A;  2Q05 A;  3RO1 A;  5EHR A;  2I6I A;  2I4G A;  4I8N A;  2Q47 A;  3MOZ A;  3CWE A;  3QCE A;  2QEP A;  1I9T A;  2GJT A;  1OHC A;  2PBN A;  2G59 A;  4AZ1 A;  4OHH A;  2F6T A;  2OZ5 A;  2NT2 A;  4TVV A;  2HNP A;  2HVL A;  3O5X A;  5K9V A;  1G1G A;  2ZMM A;  5KA0 A;  2CNH A;  1OEV A;  1FQ1 A;  1I57 A;  1BZH A;  4GRY A;  2OOQ A;  3ZM1 A;  4BPC A;  2RF6 A;  2F6V A;  2J16 A;  4JBC A;  2HB1 A;  5K9W A;  2B49 A;  1PYN A;  3D1O A;  1G7F A;  1U25 A;  3AWF A;  1EEO A;  2A8B A;  4BJO A;  2C46 A;  4S0G A;  2QCT A;  1U24 A;  2I6P A;  3QCL A;  1RPM A;  1YGU A;  3O4U A;  1QZ0 A;  1P15 A;  1Q6M A;  2NTA A;  2HC2 A;  3M4U A;  4B04 A;  4WOH A;  4D3Q A;  5LXQ B;  4Z6B A;  3LJ8 A;  2F6Z A;  4MBB A;  2I4E A;  1NNY A;  2AZR A;  3AWG A;  2F6Y A;  2CNE A;  4RDD A;  2QCJ A;  5EHP A;  1LQF A;  1OES A;  1YN9 A;  3I7Z A;  3S3H A;  4R0S A;  3D1H A;  4DGX A;  3F99 A;  2CM2 A;  2PT0 A;  1BZJ A;  1FPZ A;  2DXP A;  1ONY A;  5K23 A;  4ZI4 A;  4HRF A;  1T48 A;  4GS0 A;  5J8R A;  1U26 A;  3RGO A;  3QCI A;  2F71 A;  2WGP A;  2I1Y A;  4GE6 A;  4D3P A;  1OEM X;  5K22 A;  2I6O A;  2VEU A;  4OHI A;  1T4J A;  1KAK A;  4OHL A;  3QCM A;  2BGE A;  4RKK A;  3D42 A;  3ZM0 A;  2C7S A;  2CM3 A;  2Y2F A;  2CFV A;  1C86 A;  2FH7 A;  2I6M A;  2AHS A;  2CNF A;  2B07 A;  3V0E A;  1D5R A;  4HJP A;  2F70 A;  2QDP A;  3GXG A;  1C85 A;  1I9S A;  2CMA A;  4NWF A;  2I6J A;  3ZV2 A;  4JMK A;  3EZZ A;  4D3R A;  4ERC A;  4DGP A;  2F6W A;  4GE2 A;  2B4O A;  4QAH A;  4H34 A;  1G1F A;  2PQ5 A;  3S3E A;  2QBQ A;  3QCH A;  4QUM A;  3F81 A;  2HNQ A;  3ZM2 A;  3V0J A;  5BX1 A;  4YAA A;  1YTS A;  1PH0 A;  3I36 A;  4NX8 A;  3OLR A;  1WCH A;  3QCN A;  2QBP A;  3S4O A;  1ZC0 A;  1QXK A;  5K25 A;  4JMJ A;  2H02 A;  3BRH A;  3N0A A;  1J4X A;  4R0T A;  2J16 B;  3F9B A;  1JLN A;  3U96 A;  1RXD A;  1MKP A;  1XXP A;  2I3R A;  1V3A A;  1YZ4 A;  5BZX A;  1R6H A;  4ZRT A;  3O4T A;  3A5K A;  4KI9 A;  2B4S A;  4IKC A;  2YDU A;  1YFO A;  3AWE A;  1Q6P A;  3D9C A;  4ZN5 A;  3O4S A;  1PTU A;  2I75 A;  1NL9 A;  3BLT A;  2B4P A;  4PVG A;  2CNI A;  2OUD A;  3D1Q A;  1L8K A;  3PS5 A;  4QBW A;  3QCC A;  2I5X A;  2VEY A;  1ONZ A;  3EAX A;  2H4V A;  1C88 A;  2H4K A;  3V0G A;  1FPR A;  3SR9 A;  1WRM A;  2A3K A;  1G4U S;  1GWZ A;  2B3O A;  1EEN A;  4R30 A;  2BZL A;  4OHE A;  3EB1 A;  2BIJ A;  2HC1 A;  3QCJ A;  2GP0 A;  2PSZ A;  3ZM3 A;  4H1O A;  1XRI A;  1OEO X;  1YTN A;  5MMZ B;  2QBS A;  2HY3 A;  5KA1 A;  3D44 A;  2I4H A;  1NWL A;  1NWE A;  2Y96 A;  2J17 A;  3QCG A;  1XXV A;  1YGR A;  2CJZ A;  3RGQ A;  2NV5 A;  5BUG A;  4RI4 A;  4Y2E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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