3QCJA

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2-yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid
Total Genus 95
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
299
structure length
285
Chain Sequence
MEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase gamma
total genus 95
structure length 285
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3qcjA00
2BGDA 2A3KA 1PA9A 3BLTA 2I4HA 2VEVA 2Q05A 3ZMPA 2E0TA 4RH9A 3SR9A 1BZJA 3PS5A 4ZN5A 4NX8A 3V0IA 5BUGA 1YGRA 4RDDA 4RHGA 2B4OA 4QAPA 1D5RA 1M3GA 2BIJA 3B7OA 1FPZA 3QKQA 3V0HA 2FJNA 2CMCA 3BLUA 1U24A 1A5YA 1P15A 3D44A 3QCCA 1AAXA 1J4XA 3S4OA 2J16A 2I6IA 1YGUA 3EB1A 1SUGA 4WOHA 2WGPA 2CMBA 1T49A 1EEOA 2B3OA 2PT0A 1LYVA 3LJ8A 4GE5A 1NO6A 3ZM0A 3GXGA 5K9WA 2AZRA 3AWEA 4GFVA 4NYHA 1C88A 3NMEA 4JMKA 3EAXA 2NV5A 1YWFA 2YDUA 3O4UA 2ZMMA 3I7ZA 1YN9A 3A5JA 4OHDA 1V3AA 2F6ZA 3ZM1A 5KA4A 2HVLA 1C83A 3S4EA 2F6YA 3V0FA 2QBQA 5M43A 2QBRA 4QUNA 1NZ7A 1ZC0A 3CWEA 1ZCKA 2C46A 1OEUA 5EHRA 4Z6BA 2CFVA 1OHCA 3F9BA 4DGPA 3D9CA 2CM7A 5BZXA 2I4GA 2P6XA 3QCLA 1R6HA 3H2XA 2C7SA 4RI5A 1G7FA 1OEVA 2I6JA 3S3KA 5KA0A 1JLNA 2P4DA 3QCBA 1G1HA 4WTYA 4Y14A 2GWOA 2CM2A 1T4JA 2F70A 4IKCA 1Q6NA 4RKKA 2NTAA 2NT2A 3SMEA 3O5XA 1G4WR 2BGEA 5KAAA 2H4GA 1QXKA 3F81A 4QAHA 1PTVA 2G59A 3F99A 2F6FA 2CNGA 2OUDA 1I57A 4HRFA 2R0BA 4GFUA 4QBWA 1OETA 1LQFA 1ONZA 2F6TA 2NT7A 3RGQA 3MOZA 1FQ1A 1RPMA 2G6ZA 2NZ6A 5KADA 1NWLA 1VHRA 4MBBA 4GS0A 4OHLA 4OHIA 2A8BA 3BRHA 3M4UA 1G1FA 2H4VA 1YZ4A 3I36A 4JNBA 1Q6JA 2QCTA 2I6OA 2GP0A 1ONYA 1FPRA 3RZ2A 2H04A 2OZ5A 5MMZB 5J8RA 3D42A 2VEUA 4R0TA 3GXHA 1OEMX 1XM2A 4NNDA 2DXPA 2OOQA 1KAKA 4WU2A 2VEXA 2I6PA 5EHPA 5AWXA 1QZ0A 3AWGA 4BJOA 4HJQA 4GE2A 2JJDA 5IBSA 3D1HA 4OHEA 2MBCA 3ZV2A 4WU3A 4ERCA 2CMAA 3MMJA 2HC1A 5K22A 4R30A 2IMGA 1C85A 2FJMA 4HJPA 3BM8A 4Y2EA 5IBMA 4I8NA 4NWGA 2QBSA 2RF6A 5KACA 1PTYA 4NWFA 1L8KA 2HB1A 2F6WA 4ZI4A 1WAXA 2B4SA 2CM8A 3V0DA 1PTTA 1Q1MA 1Q6PA 5KA9A 2PQ5A 4GE6A 2SHPA 3ZM2A 3ZM3A 4B04A 2F71A 5HDEA 3EMUA 5KA8A 2QDPA 3EU0A 2B4UA 2BZLA 2CNIA 2PBNA 1G1GA 1C86A 1BZCA 1NWEA 1NL9A 5K24A 3S3FA 4R0SA 1NNYA 1RXDA 3AWFA 3QCEA 3MOWA 1JF7A 4OHHA 4YAAA 1OEOX 2I5XA 1YTNA 2I3UA 3V0EA 3QCFA 1Q6TA 2QDMA 2PSZA 3EZZA 3QCDA 3QCMA 1I9TA 3D1OA 1C87A 4RI4A 2I42A 5K9VA 1U26A 4H34A 3QCHA 2GJTA 4KYRA 2I75A 2B4PA 2BV5A 2ESBA 4D3PA 4JMJA 2I6MA 5I6VA 3RGOA 5KABA 5LXQB 1EENA 4PVGA 4GRZA 4J51A 2B49A 4BPCA 1ZZWA 2F6VA 2QCJA 3A5KA 2VEYA 1PXHA 2PI7A 3QCJA 2CM3A 4KI9A 1T48A 4S0GA 1LARA 3OLRA 2I4EA 4D3RA 5KA3A 3O4TA 5K23A 2CNFA 1OESA 3QKPA 1Q6MA 4TVVA 3QCGA 5KA2A 1ZCLA 2B07A 3QCKA 1U25A 4GWFA 4GRYA 1YPTA 4RH5A 1GWZA 1C84A 2PA5A 1I9SA 1OHEA 1XRIA 5KA7A 4YR8B 1G4US 3CM3A 2CNEA 3QCNA 2CJZA 2I1YA 5KA1A 2Y96A 3QCIA 1PH0A 1MKPA 4PYHA 3S3HA 1ECVA 2ZN7A 3ZMQA 4ZRTA 2CNHA 2HNQA 4AZ1A 1YTWA 1KAVA 2QBPA 3U96A 4QUMA 3RO1A 5GTJA 1L8GA 1YTSA 4H1OA 3O4SA 3V0GA 1X24A 1GFYA 2HC2A 3S3EA 2NLKA 1PYNA 3D1QA 4D3QA 1WCHA 1XBOA 3F41A 2OC3A 4DGXA 1PA1A 1PTUA 1XXVA 2M3VA 2Q47A 5BZZA 2QEPA 3O3LA 4ICZA 2H4KA 2F46A 2FH7A 3N0AA 1Q6SA 2VEWA 2HCMA 1BZHA 2I3RA 5K25A 2QDCA 3F9AA 1G7GA 1OHDA 1XXPA 4KYQA 2J16B 1YFOA 2H03A 1WRMA 2HY3A 2HXPA 2J17A 4JBCA 2Y2FA 5BX1A 3V0JA 2H02A 3OMHA 2AHSA 2HNPA 3I80A 4QBEA
chains in the Genus database with same CATH superfamily
2BGDA 2A3KA 1PA9A 3BLTA 2I4HA 2Y66A 2VEVA 2Q05A 3ZMPA 2E0TA 4RH9A 3SR9A 1BZJA 3PS5A 4ZN5A 4NX8A 1UAGA 3V0IA 5BUGA 1YGRA 4RDDA 4RHGA 2B4OA 4QAPA 1D5RA 1M3GA 2BIJA 3B7OA 1FPZA 3QKQA 3V0HA 2FJNA 2CMCA 3BLUA 1U24A 1A5YA 1P15A 3D44A 3QCCA 3ZM6A 4UAGA 1AAXA 1J4XA 3S4OA 2J16A 2I6IA 3LK7A 1YGUA 3EB1A 1SUGA 4WOHA 2WGPA 2CMBA 1T49A 1EEOA 2B3OA 2PT0A 1LYVA 3LJ8A 4GE5A 1NO6A 3ZM0A 3GXGA 5K9WA 2AZRA 3AWEA 4GFVA 4NYHA 1C88A 3NMEA 4JMKA 4C12A 3EAXA 2GCBA 2NV5A 1YWFA 2YDUA 3O4UA 2ZMMA 3I7ZA 1YN9A 2VTDA 3A5JA 4OHDA 1V3AA 2F6ZA 3ZM1A 5KA4A 2Y1OA 2HVLA 1C83A 3S4EA 2F6YA 3V0FA 2QBQA 5M43A 2QBRA 4QUNA 1NZ7A 1ZC0A 3CWEA 1ZCKA 2C46A 1OEUA 5EHRA 1P3DA 4Z6BA 2CFVA 1OHCA 3F9BA 4DGPA 3D9CA 2X5OA 2CM7A 5BZXA 2I4GA 2P6XA 3QCLA 4BUCA 1R6HA 3H2XA 2C7SA 4RI5A 3ZM5A 1G7FA 1OEVA 2I6JA 3S3KA 5KA0A 1JLNA 2P4DA 3QCBA 1G1HA 4WTYA 4Y14A 2GWOA 2CM2A 1T4JA 2F70A 1W7KA 4IKCA 1Q6NA 4RKKA 2NTAA 1FGSA 2NT2A 3SMEA 3O5XA 1G4WR 3PYZA 2BGEA 2F00A 5KAAA 2H4GA 1QXKA 3F81A 4QAHA 1PTVA 2G59A 3F99A 2F6FA 2CNGA 2OUDA 1I57A 4HRFA 2R0BA 4GFUA 4QBWA 1OETA 1LQFA 1ONZA 2F6TA 2NT7A 3RGQA 3MOZA 3N2AA 1FQ1A 1RPMA 2G6ZA 2NZ6A 5KADA 1NWLA 1VHRA 4MBBA 4GS0A 4OHLA 4OHIA 2A8BA 3BRHA 3M4UA 1G1FA 1P31A 1YZ4A 2H4VA 3I36A 4JNBA 1Q6JA 2QCTA 2I6OA 2GP0A 1ONYA 1FPRA 4CVMA 3RZ2A 1O5ZA 2H04A 2OZ5A 5MMZB 5J8RA 3D42A 2VEUA 4R0TA 3GXHA 1OEMX 1XM2A 4NNDA 1J6UA 2DXPA 2OOQA 1KAKA 4WU2A 2VEXA 2I6PA 5EHPA 5AWXA 1QZ0A 3AWGA 4BJOA 4HJQA 4GE2A 2JJDA 5IBSA 3D1HA 4OHEA 2MBCA 3ZV2A 3QCZA 4WU3A 4ERCA 2CMAA 3MMJA 2HC1A 5K22A 4R30A 2GC5A 2IMGA 1C85A 2FJMA 4HJPA 3BM8A 4Y2EA 5IBMA 4I8NA 4NWGA 2QBSA 2RF6A 5KACA 4QDIA 1PTYA 4NWFA 1L8KA 2HB1A 2F6WA 4ZI4A 1WAXA 2B4SA 2CM8A 3V0DA 1PTTA 2Y68A 1Q1MA 1Q6PA 5KA9A 2PQ5A 4GE6A 2SHPA 3ZM2A 3ZM3A 4B04A 2F71A 5HDEA 3EMUA 5KA8A 2QDPA 2UAGA 3EU0A 2B4UA 2BZLA 1GQYA 2CNIA 2PBNA 1GQQA 1G1GA 1C86A 1BZCA 2UUPA 1NWEA 1NL9A 1E0DA 4CVKA 5K24A 3S3FA 4R0SA 1NNYA 1RXDA 3AWFA 3QCEA 3MOWA 1JF7A 4OHHA 4YAAA 1OEOX 2I5XA 1YTNA 2I3UA 1E8CA 4BUBA 3V0EA 2JFFA 2XJAA 3QCFA 1Q6TA 2QDMA 2JFHA 2PSZA 3EZZA 2VTEA 3QCDA 3QCMA 1I9TA 3D1OA 1C87A 4RI4A 2I42A 5K9VA 1U26A 4H34A 3QCHA 2GJTA 4KYRA 2I75A 2B4PA 2WTZA 2BV5A 2ESBA 4D3PA 4JMJA 2I6MA 2GC6A 5I6VA 3RGOA 5KABA 5LXQB 1EENA 3NRSA 3MVNA 2AM1A 4PVGA 4GRZA 3UAGA 4J51A 1JBVA 2B49A 4HV4A 4BPCA 1ZZWA 2F6VA 2QCJA 3A5KA 2VEYA 1PXHA 2PI7A 3QCJA 2CM3A 4KI9A 1T48A 4S0GA 1LARA 3OLRA 2I4EA 4D3RA 5KA3A 3O4TA 5K23A 2CNFA 1OESA 3QKPA 2AM2A 1Q6MA 4QF5A 4TVVA 3QCGA 5KA2A 1ZCLA 2B07A 3QCKA 1U25A 4GWFA 4GRYA 1YPTA 4RH5A 1EEHA 1C84A 1GWZA 2PA5A 1I9SA 1OHEA 1XRIA 5A5EA 5KA7A 4YR8B 1G4US 3CM3A 2CNEA 3QCNA 2CJZA 2I1YA 2JFGA 5KA1A 2Y96A 3QCIA 4CVLA 1PH0A 4ZIYA 1MKPA 4PYHA 3S3HA 1ECVA 2ZN7A 3HN7A 3ZMQA 2Y67A 4ZRTA 2CNHA 4C13A 2GCAA 2HNQA 1W78A 4AZ1A 1YTWA 1KAVA 1GG4A 2QBPA 2UUOA 3U96A 2VORA 4QUMA 3RO1A 5GTJA 1L8GA 1YTSA 4H1OA 3O4SA 3V0GA 1X24A 2XPCA 1GFYA 2HC2A 3S3EA 2NLKA 1PYNA 3ZL8A 3D1QA 4D3QA 1WCHA 1XBOA 3F41A 2OC3A 4DGXA 1JBWA 1PA1A 1PTUA 1XXVA 2M3VA 2Q47A 5BZZA 2QEPA 3O3LA 4ICZA 2H4KA 2F46A 2FH7A 3N0AA 1Q6SA 2VEWA 5A5FA 2HCMA 1BZHA 2I3RA 5K25A 2QDCA 3F9AA 1G7GA 1OHDA 2VOSA 1XXPA 4KYQA 2J16B 1YFOA 2H03A 1WRMA 2HY3A 2HXPA 2J17A 4JBCA 2Y2FA 2WJPA 5BX1A 3V0JA 2H02A 3OMHA 2AHSA 2HNPA 3I80A 4QBEA
chains in the Genus database with same CATH topology
2BGDA 2A3KA 1PA9A 3BLTA 2I4HA 2VEVA 2Q05A 3ZMPA 2E0TA 4RH9A 3SR9A 1BZJA 3PS5A 4ZN5A 4NX8A 3V0IA 5BUGA 1YGRA 4RDDA 4RHGA 2B4OA 4QAPA 1D5RA 1M3GA 2BIJA 3B7OA 1FPZA 3QKQA 3V0HA 2FJNA 2CMCA 3BLUA 1U24A 1A5YA 1P15A 3D44A 3QCCA 1AAXA 1J4XA 3S4OA 2J16A 2I6IA 1YGUA 3EB1A 1SUGA 4WOHA 2WGPA 2CMBA 1T49A 1EEOA 2B3OA 2PT0A 1LYVA 3LJ8A 4GE5A 1NO6A 3ZM0A 3GXGA 5K9WA 2AZRA 3AWEA 4GFVA 4NYHA 1C88A 3NMEA 4JMKA 3EAXA 2NV5A 1YWFA 2YDUA 3O4UA 2ZMMA 3I7ZA 1YN9A 3A5JA 4OHDA 1V3AA 2F6ZA 3ZM1A 5KA4A 2HVLA 1C83A 3S4EA 2F6YA 3V0FA 2QBQA 5M43A 2QBRA 4QUNA 1NZ7A 1ZC0A 3CWEA 1ZCKA 2C46A 1OEUA 5EHRA 4Z6BA 2CFVA 1OHCA 3F9BA 4DGPA 3D9CA 2CM7A 5BZXA 2I4GA 2P6XA 3QCLA 1R6HA 3H2XA 2C7SA 4RI5A 1G7FA 1OEVA 2I6JA 3S3KA 5KA0A 1JLNA 2P4DA 3QCBA 1G1HA 4WTYA 4Y14A 2GWOA 2CM2A 1T4JA 2F70A 4IKCA 1Q6NA 4RKKA 2NTAA 2NT2A 3SMEA 3O5XA 1G4WR 2BGEA 5KAAA 2H4GA 1QXKA 3F81A 4QAHA 1PTVA 2G59A 3F99A 2F6FA 2CNGA 2OUDA 1I57A 4HRFA 2R0BA 4GFUA 4QBWA 1OETA 1LQFA 1ONZA 2F6TA 2NT7A 3RGQA 3MOZA 1FQ1A 1RPMA 2G6ZA 2NZ6A 5KADA 1NWLA 1VHRA 4MBBA 4GS0A 4OHLA 4OHIA 2A8BA 3BRHA 3M4UA 1G1FA 2H4VA 1YZ4A 3I36A 4JNBA 1Q6JA 2QCTA 2I6OA 2GP0A 1ONYA 1FPRA 3RZ2A 2H04A 2OZ5A 5MMZB 5J8RA 3D42A 2VEUA 4R0TA 3GXHA 1OEMX 1XM2A 4NNDA 2DXPA 2OOQA 1KAKA 4WU2A 2VEXA 2I6PA 5EHPA 5AWXA 1QZ0A 3AWGA 4BJOA 4HJQA 4GE2A 2JJDA 5IBSA 3D1HA 4OHEA 2MBCA 3ZV2A 4WU3A 4ERCA 2CMAA 3MMJA 2HC1A 5K22A 4R30A 2IMGA 1C85A 2FJMA 4HJPA 3BM8A 4Y2EA 5IBMA 4I8NA 4NWGA 2QBSA 2RF6A 5KACA 1PTYA 4NWFA 1L8KA 2HB1A 2F6WA 4ZI4A 1WAXA 2B4SA 2CM8A 3V0DA 1PTTA 1Q1MA 1Q6PA 5KA9A 2PQ5A 4GE6A 2SHPA 3ZM2A 3ZM3A 4B04A 2F71A 5HDEA 3EMUA 5KA8A 2QDPA 3EU0A 2B4UA 2BZLA 2CNIA 2PBNA 1G1GA 1C86A 1BZCA 1NWEA 1NL9A 5K24A 3S3FA 4R0SA 1NNYA 1RXDA 3AWFA 3QCEA 3MOWA 1JF7A 4OHHA 4YAAA 1OEOX 2I5XA 1YTNA 2I3UA 3V0EA 3QCFA 1Q6TA 2QDMA 2PSZA 3EZZA 3QCDA 3QCMA 1I9TA 3D1OA 1C87A 4RI4A 2I42A 5K9VA 1U26A 4H34A 3QCHA 2GJTA 4KYRA 2I75A 2B4PA 2BV5A 2ESBA 4D3PA 4JMJA 2I6MA 5I6VA 3RGOA 5KABA 5LXQB 1EENA 4PVGA 4GRZA 4J51A 2B49A 4BPCA 1ZZWA 2F6VA 2QCJA 3A5KA 2VEYA 1PXHA 2PI7A 3QCJA 2CM3A 4KI9A 1T48A 4S0GA 1LARA 3OLRA 2I4EA 4D3RA 5KA3A 3O4TA 5K23A 2CNFA 1OESA 3QKPA 1Q6MA 4TVVA 3QCGA 5KA2A 1ZCLA 2B07A 3QCKA 1U25A 4GWFA 4GRYA 1YPTA 4RH5A 1GWZA 1C84A 2PA5A 1I9SA 1OHEA 1XRIA 5KA7A 4YR8B 1G4US 3CM3A 2CNEA 3QCNA 2CJZA 2I1YA 5KA1A 2Y96A 3QCIA 1PH0A 1MKPA 4PYHA 3S3HA 1ECVA 2ZN7A 3ZMQA 4ZRTA 2CNHA 2HNQA 4AZ1A 1YTWA 1KAVA 2QBPA 3U96A 4QUMA 3RO1A 5GTJA 1L8GA 1YTSA 4H1OA 3O4SA 3V0GA 1X24A 1GFYA 2HC2A 3S3EA 2NLKA 1PYNA 3D1QA 4D3QA 1WCHA 1XBOA 3F41A 2OC3A 4DGXA 1PA1A 1PTUA 1XXVA 2M3VA 2Q47A 5BZZA 2QEPA 3O3LA 4ICZA 2H4KA 2F46A 2FH7A 3N0AA 1Q6SA 2VEWA 2HCMA 1BZHA 2I3RA 5K25A 2QDCA 3F9AA 1G7GA 1OHDA 1XXPA 4KYQA 2J16B 1YFOA 2H03A 1WRMA 2HY3A 2HXPA 2J17A 4JBCA 2Y2FA 5BX1A 3V0JA 2H02A 3OMHA 2AHSA 2HNPA 3I80A 4QBEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BGD A;  2A3K A;  1PA9 A;  3BLT A;  2I4H A;  2VEV A;  2Q05 A;  3ZMP A;  2E0T A;  4RH9 A;  3SR9 A;  1BZJ A;  3PS5 A;  4ZN5 A;  4NX8 A;  3V0I A;  5BUG A;  1YGR A;  4RDD A;  4RHG A;  2B4O A;  4QAP A;  1D5R A;  1M3G A;  2BIJ A;  3B7O A;  1FPZ A;  3QKQ A;  3V0H A;  2FJN A;  2CMC A;  3BLU A;  1U24 A;  1A5Y A;  1P15 A;  3D44 A;  3QCC A;  1AAX A;  1J4X A;  3S4O A;  2J16 A;  2I6I A;  1YGU A;  3EB1 A;  1SUG A;  4WOH A;  2WGP A;  2CMB A;  1T49 A;  1EEO A;  2B3O A;  2PT0 A;  1LYV A;  3LJ8 A;  4GE5 A;  1NO6 A;  3ZM0 A;  3GXG A;  5K9W A;  2AZR A;  3AWE A;  4GFV A;  4NYH A;  1C88 A;  3NME A;  4JMK A;  3EAX A;  2NV5 A;  1YWF A;  2YDU A;  3O4U A;  2ZMM A;  3I7Z A;  1YN9 A;  3A5J A;  4OHD A;  1V3A A;  2F6Z A;  3ZM1 A;  5KA4 A;  2HVL A;  1C83 A;  3S4E A;  2F6Y A;  3V0F A;  2QBQ A;  5M43 A;  2QBR A;  4QUN A;  1NZ7 A;  1ZC0 A;  3CWE A;  1ZCK A;  2C46 A;  1OEU A;  5EHR A;  4Z6B A;  2CFV A;  1OHC A;  3F9B A;  4DGP A;  3D9C A;  2CM7 A;  5BZX A;  2I4G A;  2P6X A;  3QCL A;  1R6H A;  3H2X A;  2C7S A;  4RI5 A;  1G7F A;  1OEV A;  2I6J A;  3S3K A;  5KA0 A;  1JLN A;  2P4D A;  3QCB A;  1G1H A;  4WTY A;  4Y14 A;  2GWO A;  2CM2 A;  1T4J A;  2F70 A;  4IKC A;  1Q6N A;  4RKK A;  2NTA A;  2NT2 A;  3SME A;  3O5X A;  1G4W R;  2BGE A;  5KAA A;  2H4G A;  1QXK A;  3F81 A;  4QAH A;  1PTV A;  2G59 A;  3F99 A;  2F6F A;  2CNG A;  2OUD A;  1I57 A;  4HRF A;  2R0B A;  4GFU A;  4QBW A;  1OET A;  1LQF A;  1ONZ A;  2F6T A;  2NT7 A;  3RGQ A;  3MOZ A;  1FQ1 A;  1RPM A;  2G6Z A;  2NZ6 A;  5KAD A;  1NWL A;  1VHR A;  4MBB A;  4GS0 A;  4OHL A;  4OHI A;  2A8B A;  3BRH A;  3M4U A;  1G1F A;  2H4V A;  1YZ4 A;  3I36 A;  4JNB A;  1Q6J A;  2QCT A;  2I6O A;  2GP0 A;  1ONY A;  1FPR A;  3RZ2 A;  2H04 A;  2OZ5 A;  5MMZ B;  5J8R A;  3D42 A;  2VEU A;  4R0T A;  3GXH A;  1OEM X;  1XM2 A;  4NND A;  2DXP A;  2OOQ A;  1KAK A;  4WU2 A;  2VEX A;  2I6P A;  5EHP A;  5AWX A;  1QZ0 A;  3AWG A;  4BJO A;  4HJQ A;  4GE2 A;  2JJD A;  5IBS A;  3D1H A;  4OHE A;  2MBC A;  3ZV2 A;  4WU3 A;  4ERC A;  2CMA A;  3MMJ A;  2HC1 A;  5K22 A;  4R30 A;  2IMG A;  1C85 A;  2FJM A;  4HJP A;  3BM8 A;  4Y2E A;  5IBM A;  4I8N A;  4NWG A;  2QBS A;  2RF6 A;  5KAC A;  1PTY A;  4NWF A;  1L8K A;  2HB1 A;  2F6W A;  4ZI4 A;  1WAX A;  2B4S A;  2CM8 A;  3V0D A;  1PTT A;  1Q1M A;  1Q6P A;  5KA9 A;  2PQ5 A;  4GE6 A;  2SHP A;  3ZM2 A;  3ZM3 A;  4B04 A;  2F71 A;  5HDE A;  3EMU A;  5KA8 A;  2QDP A;  3EU0 A;  2B4U A;  2BZL A;  2CNI A;  2PBN A;  1G1G A;  1C86 A;  1BZC A;  1NWE A;  1NL9 A;  5K24 A;  3S3F A;  4R0S A;  1NNY A;  1RXD A;  3AWF A;  3QCE A;  3MOW A;  1JF7 A;  4OHH A;  4YAA A;  1OEO X;  2I5X A;  1YTN A;  2I3U A;  3V0E A;  3QCF A;  1Q6T A;  2QDM A;  2PSZ A;  3EZZ A;  3QCD A;  3QCM A;  1I9T A;  3D1O A;  1C87 A;  4RI4 A;  2I42 A;  5K9V A;  1U26 A;  4H34 A;  3QCH A;  2GJT A;  4KYR A;  2I75 A;  2B4P A;  2BV5 A;  2ESB A;  4D3P A;  4JMJ A;  2I6M A;  5I6V A;  3RGO A;  5KAB A;  5LXQ B;  1EEN A;  4PVG A;  4GRZ A;  4J51 A;  2B49 A;  4BPC A;  1ZZW A;  2F6V A;  2QCJ A;  3A5K A;  2VEY A;  1PXH A;  2PI7 A;  3QCJ A;  2CM3 A;  4KI9 A;  1T48 A;  4S0G A;  1LAR A;  3OLR A;  2I4E A;  4D3R A;  5KA3 A;  3O4T A;  5K23 A;  2CNF A;  1OES A;  3QKP A;  1Q6M A;  4TVV A;  3QCG A;  5KA2 A;  1ZCL A;  2B07 A;  3QCK A;  1U25 A;  4GWF A;  4GRY A;  1YPT A;  4RH5 A;  1GWZ A;  1C84 A;  2PA5 A;  1I9S A;  1OHE A;  1XRI A;  5KA7 A;  4YR8 B;  1G4U S;  3CM3 A;  2CNE A;  3QCN A;  2CJZ A;  2I1Y A;  5KA1 A;  2Y96 A;  3QCI A;  1PH0 A;  1MKP A;  4PYH A;  3S3H A;  1ECV A;  2ZN7 A;  3ZMQ A;  4ZRT A;  2CNH A;  2HNQ A;  4AZ1 A;  1YTW A;  1KAV A;  2QBP A;  3U96 A;  4QUM A;  3RO1 A;  5GTJ A;  1L8G A;  1YTS A;  4H1O A;  3O4S A;  3V0G A;  1X24 A;  1GFY A;  2HC2 A;  3S3E A;  2NLK A;  1PYN A;  3D1Q A;  4D3Q A;  1WCH A;  1XBO A;  3F41 A;  2OC3 A;  4DGX A;  1PA1 A;  1PTU A;  1XXV A;  2M3V A;  2Q47 A;  5BZZ A;  2QEP A;  3O3L A;  4ICZ A;  2H4K A;  2F46 A;  2FH7 A;  3N0A A;  1Q6S A;  2VEW A;  2HCM A;  1BZH A;  2I3R A;  5K25 A;  2QDC A;  3F9A A;  1G7G A;  1OHD A;  1XXP A;  4KYQ A;  2J16 B;  1YFO A;  2H03 A;  1WRM A;  2HY3 A;  2HXP A;  2J17 A;  4JBC A;  2Y2F A;  5BX1 A;  3V0J A;  2H02 A;  3OMH A;  2AHS A;  2HNP A;  3I80 A;  4QBE A; 
#chains in the Genus database with same CATH topology
 2BGD A;  2A3K A;  1PA9 A;  3BLT A;  2I4H A;  2Y66 A;  2VEV A;  2Q05 A;  3ZMP A;  2E0T A;  4RH9 A;  3SR9 A;  1BZJ A;  3PS5 A;  4ZN5 A;  4NX8 A;  1UAG A;  3V0I A;  5BUG A;  1YGR A;  4RDD A;  4RHG A;  2B4O A;  4QAP A;  1D5R A;  1M3G A;  2BIJ A;  3B7O A;  1FPZ A;  3QKQ A;  3V0H A;  2FJN A;  2CMC A;  3BLU A;  1U24 A;  1A5Y A;  1P15 A;  3D44 A;  3QCC A;  3ZM6 A;  4UAG A;  1AAX A;  1J4X A;  3S4O A;  2J16 A;  2I6I A;  3LK7 A;  1YGU A;  3EB1 A;  1SUG A;  4WOH A;  2WGP A;  2CMB A;  1T49 A;  1EEO A;  2B3O A;  2PT0 A;  1LYV A;  3LJ8 A;  4GE5 A;  1NO6 A;  3ZM0 A;  3GXG A;  5K9W A;  2AZR A;  3AWE A;  4GFV A;  4NYH A;  1C88 A;  3NME A;  4JMK A;  4C12 A;  3EAX A;  2GCB A;  2NV5 A;  1YWF A;  2YDU A;  3O4U A;  2ZMM A;  3I7Z A;  1YN9 A;  2VTD A;  3A5J A;  4OHD A;  1V3A A;  2F6Z A;  3ZM1 A;  5KA4 A;  2Y1O A;  2HVL A;  1C83 A;  3S4E A;  2F6Y A;  3V0F A;  2QBQ A;  5M43 A;  2QBR A;  4QUN A;  1NZ7 A;  1ZC0 A;  3CWE A;  1ZCK A;  2C46 A;  1OEU A;  5EHR A;  1P3D A;  4Z6B A;  2CFV A;  1OHC A;  3F9B A;  4DGP A;  3D9C A;  2X5O A;  2CM7 A;  5BZX A;  2I4G A;  2P6X A;  3QCL A;  4BUC A;  1R6H A;  3H2X A;  2C7S A;  4RI5 A;  3ZM5 A;  1G7F A;  1OEV A;  2I6J A;  3S3K A;  5KA0 A;  1JLN A;  2P4D A;  3QCB A;  1G1H A;  4WTY A;  4Y14 A;  2GWO A;  2CM2 A;  1T4J A;  2F70 A;  1W7K A;  4IKC A;  1Q6N A;  4RKK A;  2NTA A;  1FGS A;  2NT2 A;  3SME A;  3O5X A;  1G4W R;  3PYZ A;  2BGE A;  2F00 A;  5KAA A;  2H4G A;  1QXK A;  3F81 A;  4QAH A;  1PTV A;  2G59 A;  3F99 A;  2F6F A;  2CNG A;  2OUD A;  1I57 A;  4HRF A;  2R0B A;  4GFU A;  4QBW A;  1OET A;  1LQF A;  1ONZ A;  2F6T A;  2NT7 A;  3RGQ A;  3MOZ A;  3N2A A;  1FQ1 A;  1RPM A;  2G6Z A;  2NZ6 A;  5KAD A;  1NWL A;  1VHR A;  4MBB A;  4GS0 A;  4OHL A;  4OHI A;  2A8B A;  3BRH A;  3M4U A;  1G1F A;  1P31 A;  1YZ4 A;  2H4V A;  3I36 A;  4JNB A;  1Q6J A;  2QCT A;  2I6O A;  2GP0 A;  1ONY A;  1FPR A;  4CVM A;  3RZ2 A;  1O5Z A;  2H04 A;  2OZ5 A;  5MMZ B;  5J8R A;  3D42 A;  2VEU A;  4R0T A;  3GXH A;  1OEM X;  1XM2 A;  4NND A;  1J6U A;  2DXP A;  2OOQ A;  1KAK A;  4WU2 A;  2VEX A;  2I6P A;  5EHP A;  5AWX A;  1QZ0 A;  3AWG A;  4BJO A;  4HJQ A;  4GE2 A;  2JJD A;  5IBS A;  3D1H A;  4OHE A;  2MBC A;  3ZV2 A;  3QCZ A;  4WU3 A;  4ERC A;  2CMA A;  3MMJ A;  2HC1 A;  5K22 A;  4R30 A;  2GC5 A;  2IMG A;  1C85 A;  2FJM A;  4HJP A;  3BM8 A;  4Y2E A;  5IBM A;  4I8N A;  4NWG A;  2QBS A;  2RF6 A;  5KAC A;  4QDI A;  1PTY A;  4NWF A;  1L8K A;  2HB1 A;  2F6W A;  4ZI4 A;  1WAX A;  2B4S A;  2CM8 A;  3V0D A;  1PTT A;  2Y68 A;  1Q1M A;  1Q6P A;  5KA9 A;  2PQ5 A;  4GE6 A;  2SHP A;  3ZM2 A;  3ZM3 A;  4B04 A;  2F71 A;  5HDE A;  3EMU A;  5KA8 A;  2QDP A;  2UAG A;  3EU0 A;  2B4U A;  2BZL A;  1GQY A;  2CNI A;  2PBN A;  1GQQ A;  1G1G A;  1C86 A;  1BZC A;  2UUP A;  1NWE A;  1NL9 A;  1E0D A;  4CVK A;  5K24 A;  3S3F A;  4R0S A;  1NNY A;  1RXD A;  3AWF A;  3QCE A;  3MOW A;  1JF7 A;  4OHH A;  4YAA A;  1OEO X;  2I5X A;  1YTN A;  2I3U A;  1E8C A;  4BUB A;  3V0E A;  2JFF A;  2XJA A;  3QCF A;  1Q6T A;  2QDM A;  2JFH A;  2PSZ A;  3EZZ A;  2VTE A;  3QCD A;  3QCM A;  1I9T A;  3D1O A;  1C87 A;  4RI4 A;  2I42 A;  5K9V A;  1U26 A;  4H34 A;  3QCH A;  2GJT A;  4KYR A;  2I75 A;  2B4P A;  2WTZ A;  2BV5 A;  2ESB A;  4D3P A;  4JMJ A;  2I6M A;  2GC6 A;  5I6V A;  3RGO A;  5KAB A;  5LXQ B;  1EEN A;  3NRS A;  3MVN A;  2AM1 A;  4PVG A;  4GRZ A;  3UAG A;  4J51 A;  1JBV A;  2B49 A;  4HV4 A;  4BPC A;  1ZZW A;  2F6V A;  2QCJ A;  3A5K A;  2VEY A;  1PXH A;  2PI7 A;  3QCJ A;  2CM3 A;  4KI9 A;  1T48 A;  4S0G A;  1LAR A;  3OLR A;  2I4E A;  4D3R A;  5KA3 A;  3O4T A;  5K23 A;  2CNF A;  1OES A;  3QKP A;  2AM2 A;  1Q6M A;  4QF5 A;  4TVV A;  3QCG A;  5KA2 A;  1ZCL A;  2B07 A;  3QCK A;  1U25 A;  4GWF A;  4GRY A;  1YPT A;  4RH5 A;  1EEH A;  1C84 A;  1GWZ A;  2PA5 A;  1I9S A;  1OHE A;  1XRI A;  5A5E A;  5KA7 A;  4YR8 B;  1G4U S;  3CM3 A;  2CNE A;  3QCN A;  2CJZ A;  2I1Y A;  2JFG A;  5KA1 A;  2Y96 A;  3QCI A;  4CVL A;  1PH0 A;  4ZIY A;  1MKP A;  4PYH A;  3S3H A;  1ECV A;  2ZN7 A;  3HN7 A;  3ZMQ A;  2Y67 A;  4ZRT A;  2CNH A;  4C13 A;  2GCA A;  2HNQ A;  1W78 A;  4AZ1 A;  1YTW A;  1KAV A;  1GG4 A;  2QBP A;  2UUO A;  3U96 A;  2VOR A;  4QUM A;  3RO1 A;  5GTJ A;  1L8G A;  1YTS A;  4H1O A;  3O4S A;  3V0G A;  1X24 A;  2XPC A;  1GFY A;  2HC2 A;  3S3E A;  2NLK A;  1PYN A;  3ZL8 A;  3D1Q A;  4D3Q A;  1WCH A;  1XBO A;  3F41 A;  2OC3 A;  4DGX A;  1JBW A;  1PA1 A;  1PTU A;  1XXV A;  2M3V A;  2Q47 A;  5BZZ A;  2QEP A;  3O3L A;  4ICZ A;  2H4K A;  2F46 A;  2FH7 A;  3N0A A;  1Q6S A;  2VEW A;  5A5F A;  2HCM A;  1BZH A;  2I3R A;  5K25 A;  2QDC A;  3F9A A;  1G7G A;  1OHD A;  2VOS A;  1XXP A;  4KYQ A;  2J16 B;  1YFO A;  2H03 A;  1WRM A;  2HY3 A;  2HXP A;  2J17 A;  4JBC A;  2Y2F A;  2WJP A;  5BX1 A;  3V0J A;  2H02 A;  3OMH A;  2AHS A;  2HNP A;  3I80 A;  4QBE A; 
#chains in the Genus database with same CATH homology
 2BGD A;  2A3K A;  1PA9 A;  3BLT A;  2I4H A;  2VEV A;  2Q05 A;  3ZMP A;  2E0T A;  4RH9 A;  3SR9 A;  1BZJ A;  3PS5 A;  4ZN5 A;  4NX8 A;  3V0I A;  5BUG A;  1YGR A;  4RDD A;  4RHG A;  2B4O A;  4QAP A;  1D5R A;  1M3G A;  2BIJ A;  3B7O A;  1FPZ A;  3QKQ A;  3V0H A;  2FJN A;  2CMC A;  3BLU A;  1U24 A;  1A5Y A;  1P15 A;  3D44 A;  3QCC A;  1AAX A;  1J4X A;  3S4O A;  2J16 A;  2I6I A;  1YGU A;  3EB1 A;  1SUG A;  4WOH A;  2WGP A;  2CMB A;  1T49 A;  1EEO A;  2B3O A;  2PT0 A;  1LYV A;  3LJ8 A;  4GE5 A;  1NO6 A;  3ZM0 A;  3GXG A;  5K9W A;  2AZR A;  3AWE A;  4GFV A;  4NYH A;  1C88 A;  3NME A;  4JMK A;  3EAX A;  2NV5 A;  1YWF A;  2YDU A;  3O4U A;  2ZMM A;  3I7Z A;  1YN9 A;  3A5J A;  4OHD A;  1V3A A;  2F6Z A;  3ZM1 A;  5KA4 A;  2HVL A;  1C83 A;  3S4E A;  2F6Y A;  3V0F A;  2QBQ A;  5M43 A;  2QBR A;  4QUN A;  1NZ7 A;  1ZC0 A;  3CWE A;  1ZCK A;  2C46 A;  1OEU A;  5EHR A;  4Z6B A;  2CFV A;  1OHC A;  3F9B A;  4DGP A;  3D9C A;  2CM7 A;  5BZX A;  2I4G A;  2P6X A;  3QCL A;  1R6H A;  3H2X A;  2C7S A;  4RI5 A;  1G7F A;  1OEV A;  2I6J A;  3S3K A;  5KA0 A;  1JLN A;  2P4D A;  3QCB A;  1G1H A;  4WTY A;  4Y14 A;  2GWO A;  2CM2 A;  1T4J A;  2F70 A;  4IKC A;  1Q6N A;  4RKK A;  2NTA A;  2NT2 A;  3SME A;  3O5X A;  1G4W R;  2BGE A;  5KAA A;  2H4G A;  1QXK A;  3F81 A;  4QAH A;  1PTV A;  2G59 A;  3F99 A;  2F6F A;  2CNG A;  2OUD A;  1I57 A;  4HRF A;  2R0B A;  4GFU A;  4QBW A;  1OET A;  1LQF A;  1ONZ A;  2F6T A;  2NT7 A;  3RGQ A;  3MOZ A;  1FQ1 A;  1RPM A;  2G6Z A;  2NZ6 A;  5KAD A;  1NWL A;  1VHR A;  4MBB A;  4GS0 A;  4OHL A;  4OHI A;  2A8B A;  3BRH A;  3M4U A;  1G1F A;  2H4V A;  1YZ4 A;  3I36 A;  4JNB A;  1Q6J A;  2QCT A;  2I6O A;  2GP0 A;  1ONY A;  1FPR A;  3RZ2 A;  2H04 A;  2OZ5 A;  5MMZ B;  5J8R A;  3D42 A;  2VEU A;  4R0T A;  3GXH A;  1OEM X;  1XM2 A;  4NND A;  2DXP A;  2OOQ A;  1KAK A;  4WU2 A;  2VEX A;  2I6P A;  5EHP A;  5AWX A;  1QZ0 A;  3AWG A;  4BJO A;  4HJQ A;  4GE2 A;  2JJD A;  5IBS A;  3D1H A;  4OHE A;  2MBC A;  3ZV2 A;  4WU3 A;  4ERC A;  2CMA A;  3MMJ A;  2HC1 A;  5K22 A;  4R30 A;  2IMG A;  1C85 A;  2FJM A;  4HJP A;  3BM8 A;  4Y2E A;  5IBM A;  4I8N A;  4NWG A;  2QBS A;  2RF6 A;  5KAC A;  1PTY A;  4NWF A;  1L8K A;  2HB1 A;  2F6W A;  4ZI4 A;  1WAX A;  2B4S A;  2CM8 A;  3V0D A;  1PTT A;  1Q1M A;  1Q6P A;  5KA9 A;  2PQ5 A;  4GE6 A;  2SHP A;  3ZM2 A;  3ZM3 A;  4B04 A;  2F71 A;  5HDE A;  3EMU A;  5KA8 A;  2QDP A;  3EU0 A;  2B4U A;  2BZL A;  2CNI A;  2PBN A;  1G1G A;  1C86 A;  1BZC A;  1NWE A;  1NL9 A;  5K24 A;  3S3F A;  4R0S A;  1NNY A;  1RXD A;  3AWF A;  3QCE A;  3MOW A;  1JF7 A;  4OHH A;  4YAA A;  1OEO X;  2I5X A;  1YTN A;  2I3U A;  3V0E A;  3QCF A;  1Q6T A;  2QDM A;  2PSZ A;  3EZZ A;  3QCD A;  3QCM A;  1I9T A;  3D1O A;  1C87 A;  4RI4 A;  2I42 A;  5K9V A;  1U26 A;  4H34 A;  3QCH A;  2GJT A;  4KYR A;  2I75 A;  2B4P A;  2BV5 A;  2ESB A;  4D3P A;  4JMJ A;  2I6M A;  5I6V A;  3RGO A;  5KAB A;  5LXQ B;  1EEN A;  4PVG A;  4GRZ A;  4J51 A;  2B49 A;  4BPC A;  1ZZW A;  2F6V A;  2QCJ A;  3A5K A;  2VEY A;  1PXH A;  2PI7 A;  3QCJ A;  2CM3 A;  4KI9 A;  1T48 A;  4S0G A;  1LAR A;  3OLR A;  2I4E A;  4D3R A;  5KA3 A;  3O4T A;  5K23 A;  2CNF A;  1OES A;  3QKP A;  1Q6M A;  4TVV A;  3QCG A;  5KA2 A;  1ZCL A;  2B07 A;  3QCK A;  1U25 A;  4GWF A;  4GRY A;  1YPT A;  4RH5 A;  1GWZ A;  1C84 A;  2PA5 A;  1I9S A;  1OHE A;  1XRI A;  5KA7 A;  4YR8 B;  1G4U S;  3CM3 A;  2CNE A;  3QCN A;  2CJZ A;  2I1Y A;  5KA1 A;  2Y96 A;  3QCI A;  1PH0 A;  1MKP A;  4PYH A;  3S3H A;  1ECV A;  2ZN7 A;  3ZMQ A;  4ZRT A;  2CNH A;  2HNQ A;  4AZ1 A;  1YTW A;  1KAV A;  2QBP A;  3U96 A;  4QUM A;  3RO1 A;  5GTJ A;  1L8G A;  1YTS A;  4H1O A;  3O4S A;  3V0G A;  1X24 A;  1GFY A;  2HC2 A;  3S3E A;  2NLK A;  1PYN A;  3D1Q A;  4D3Q A;  1WCH A;  1XBO A;  3F41 A;  2OC3 A;  4DGX A;  1PA1 A;  1PTU A;  1XXV A;  2M3V A;  2Q47 A;  5BZZ A;  2QEP A;  3O3L A;  4ICZ A;  2H4K A;  2F46 A;  2FH7 A;  3N0A A;  1Q6S A;  2VEW A;  2HCM A;  1BZH A;  2I3R A;  5K25 A;  2QDC A;  3F9A A;  1G7G A;  1OHD A;  1XXP A;  4KYQ A;  2J16 B;  1YFO A;  2H03 A;  1WRM A;  2HY3 A;  2HXP A;  2J17 A;  4JBC A;  2Y2F A;  5BX1 A;  3V0J A;  2H02 A;  3OMH A;  2AHS A;  2HNP A;  3I80 A;  4QBE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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