4GE5 | Genus

Total Genus 97

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	97
sequence length	307
structure length	298
Chain Sequence	SVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase/hydrolase inhibitor
source organism	Homo sapiens
publication title	A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. pubmed doi rcsb
molecule keywords	Tyrosine-protein phosphatase non-receptor type 9
total genus	97
structure length	298
sequence length	307
chains with identical sequence	B
ec nomenclature	ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date	2012-08-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00102	Y_phosphatase	Protein-tyrosine phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.190.10	Alpha Beta	Alpha-Beta Complex	Protein-Tyrosine Phosphatase; Chain A	Protein tyrosine phosphatase superfamily	4ge5A00

1Q6NA 2QDCA 3I7ZA 4Y14A 3QCKA 4Y2EA 3O4SA 1G1GA 4RHGA 4PVGA 4WTYA 2IMGA 2Q47A 2H4VA 2QCTA 1R6HA 2OZ5A 2NLKA 2H03A 1YGRA 3RGOA 4PYHA 3O3LA 4TVVA 1RXDA 4R0SA 2I6MA 4RI5A 4GRZA 4BJOA 3V0GA 1G4WR 3QKPA 1FQ1A 1RPMA 2VEWA 1SUGA 3OMHA 3BM8A 2FH7A 1KAVA 2HC2A 1YPTA 1YTNA 5KA1A 4JMJA 5EHRA 3QCBA 1I9TA 1EEOA 4DGPA 1OEVA 1XM2A 2B4UA 1P15A 3F41A 1YFOA 2CM7A 3BLUA 5KA0A 2I3UA 3RGQA 3MOZA 1YTWA 5K9WA 4WOHA 1QXKA 2CJZA 3EZZA 4QUMA 1JLNA 4H1OA 2BGDA 3F9BA 5KA7A 2HB1A 1FPRA 3S4EA 4NNDA 5KACA 3EU0A 2QCJA 3MMJA 2BV5A 3GXGA 5KA8A 1YTSA 1T4JA 2ZN7A 2OOQA 2CMBA 2I42A 2B3OA 3N0AA 1C88A 2I4HA 3S3EA 2B07A 1G1FA 4NX8A 3QCNA 1PA9A 4QBEA 1ZCLA 5KA2A 2BGEA 5KAAA 4R30A 4NWFA 3ZMQA 1OESA 1YWFA 2F6ZA 4RH9A 1XBOA 4Z6BA 4ICZA 5K24A 4QAPA 2Y2FA 1MKPA 3F99A 1JF7A 1V3AA 1YN9A 4KYQA 1PTUA 2CNIA 3CM3A 4RDDA 4OHEA 1ONYA 2PQ5A 1Q6PA 1WCHA 1PH0A 1PTTA 1WAXA 1U26A 4J51A 2J16A 5MMZB 3S3FA 2H4GA 1C84A 2H02A 3M4UA 3SMEA 1Q6TA 2GWOA 2CNHA 2CNFA 2QBSA 1XXPA 4WU2A 2DXPA 1XRIA 2F6YA 1I57A 4QAHA 4HJQA 4OHDA 3QKQA 5HDEA 1BZHA 5BUGA 2I6IA 4KI9A 2A3KA 2VEYA 2F6WA 4ZRTA 1U25A 3ZM2A 4R0TA 1BZCA 5LXQB 2F70A 2F46A 2CM8A 1GWZA 4S0GA 3V0DA 1PTYA 5IBSA 5EHPA 2QEPA 4OHHA 3V0HA 1KAKA 2HC1A 1ONZA 2I4GA 2OC3A 2I1YA 3ZM0A 3EAXA 5K23A 3O4TA 3F9AA 3PS5A 1OEUA 4DGXA 3ZM1A 1T49A 3BLTA 2VEXA 3LJ8A 2NT2A 3QCIA 3GXHA 1G7FA 3MOWA 3S3KA 1ECVA 2ESBA 1C85A 3O4UA 4GRYA 1OETA 4JNBA 2M3VA 2P4DA 5K25A 2R0BA 4RI4A 2QBQA 1J4XA 4GE5A 4YAAA 2I4EA 2F6VA 3QCGA 5KA3A 2OUDA 2G59A 4ERCA 2PI7A 1D5RA 4D3QA 4NWGA 2NZ6A 1NZ7A 2ZMMA 2HVLA 2C46A 2HXPA 2CMCA 3U96A 3V0JA 5KABA 4MBBA 2HNQA 1ZC0A 2CNEA 1Q6MA 2CM2A 1NO6A 1L8GA 4B04A 2H4KA 3QCJA 4GFUA 4BPCA 2PSZA 2Y96A 2B4PA 3V0FA 2FJNA 4D3RA 5BX1A 3AWGA 3ZV2A 2YDUA 2BZLA 2HCMA 1PYNA 2G6ZA 2NTAA 1PA1A 4GS0A 4GWFA 3D1QA 5I6VA 2C7SA 2NT7A 4HRFA 2F71A 1YZ4A 3CWEA 1ZCKA 4GE6A 4HJPA 4YR8B 3AWFA 2QDMA 3I80A 3A5KA 3ZMPA 2CMAA 2JJDA 3ZM3A 2BIJA 1GFYA 1G7GA 3O5XA 1XXVA 2NV5A 2GJTA 4RH5A 2B4OA 3QCDA 1G4US 1L8KA 3B7OA 2I6JA 3QCLA 2F6FA 5BZXA 2FJMA 3RO1A 2QBPA 1NL9A 1FPZA 2A8BA 2J17A 1X24A 3BRHA 4I8NA 1U24A 4GFVA 5AWXA 1LYVA 4AZ1A 2P6XA 2PA5A 2I6PA 2MBCA 3D44A 3I36A 4NYHA 3AWEA 1EENA 5BZZA 3D1HA 1WRMA 2CFVA 1Q6JA 4GE2A 1G1HA 4KYRA 3OLRA 2QBRA 1BZJA 4JBCA 3QCHA 2PT0A 1OEMX 1T48A 1C86A 2AHSA 2J16B 3RZ2A 4WU3A 4IKCA 3EMUA 1OHCA 3QCEA 4ZN5A 2AZRA 3SR9A 1I9SA 3A5JA 2VEUA 1NWEA 1YGUA 2PBNA 3S4OA 5M43A 5J8RA 1PXHA 1OEOX 1AAXA 1C83A 2I6OA 5K22A 2I3RA 4QBWA 1Q6SA 2B4SA 2I5XA 1VHRA 2H04A 1NWLA 1A5YA 4D3PA 2I75A 2CNGA 1LARA 3D42A 2SHPA 3D9CA 5KA4A 1ZZWA 2QDPA 2HNPA 1OHEA 1PTVA 5KADA 3S3HA 3H2XA 3EB1A 1Q1MA 2VEVA 2GP0A 2RF6A 4RKKA 2E0TA 5KA9A 5K9VA 1QZ0A 2F6TA 3QCMA 2WGPA 5GTJA 1NNYA 3NMEA 4ZI4A 1OHDA 4OHIA 3F81A 5IBMA 4QUNA 4OHLA 2HY3A 2Q05A 3D1OA 4JMKA 1LQFA 3QCFA 2CM3A 3V0EA 3QCCA 1C87A 3V0IA 2B49A 4H34A 1M3GA
chains in the Genus database with same CATH superfamily

1Q6NA 2QDCA 3I7ZA 1GQYA 4Y14A 3QCKA 4Y2EA 3O4SA 1W78A 1G1GA 4RHGA 1E0DA 4PVGA 4WTYA 2IMGA 2Q47A 2H4VA 2QCTA 4BUBA 1R6HA 2OZ5A 2NLKA 2H03A 1YGRA 3RGOA 4PYHA 3O3LA 4TVVA 1RXDA 4R0SA 2I6MA 4RI5A 4GRZA 4BJOA 3V0GA 1G4WR 3QKPA 2GC5A 1FQ1A 3N2AA 2Y68A 1RPMA 2VEWA 2VTEA 1SUGA 3OMHA 3BM8A 2FH7A 2Y66A 1KAVA 2HC2A 1YPTA 1YTNA 5KA1A 4JMJA 5EHRA 3ZL8A 3QCBA 2VOSA 1I9TA 1EEOA 4DGPA 1OEVA 1XM2A 2B4UA 1P15A 3F41A 1YFOA 2CM7A 2XPCA 1P31A 3BLUA 5KA0A 2I3UA 3RGQA 3MOZA 1YTWA 5K9WA 4WOHA 2GCAA 1QXKA 2CJZA 3EZZA 4QUMA 1JLNA 4H1OA 1JBVA 2BGDA 3F9BA 5KA7A 2HB1A 1FPRA 4CVLA 3S4EA 4NNDA 5KACA 3EU0A 2QCJA 3MMJA 2BV5A 3GXGA 5KA8A 4HV4A 1YTSA 1T4JA 2ZN7A 2OOQA 4C13A 2CMBA 2I42A 4QF5A 2B3OA 3N0AA 1C88A 1J6UA 2I4HA 3S3EA 2B07A 2XJAA 1G1FA 4NX8A 3QCNA 1PA9A 4QBEA 1ZCLA 5KA2A 2BGEA 4ZIYA 5KAAA 4R30A 1E8CA 4NWFA 3ZMQA 1OESA 1YWFA 2F6ZA 4RH9A 1XBOA 4Z6BA 1W7KA 4ICZA 5K24A 2GCBA 4QAPA 2JFGA 2Y2FA 1MKPA 3F99A 1JF7A 1V3AA 3HN7A 3ZM5A 1YN9A 4KYQA 4UAGA 1PTUA 2CNIA 3CM3A 3LK7A 4RDDA 4OHEA 1ONYA 2PQ5A 1Q6PA 1WCHA 1PH0A 2JFHA 1PTTA 1WAXA 1U26A 4J51A 2J16A 5MMZB 3S3FA 2H4GA 2F00A 1C84A 2H02A 3M4UA 3SMEA 1Q6TA 2GWOA 2CNHA 2CNFA 2QBSA 3QCZA 1XXPA 4WU2A 2DXPA 1XRIA 2F6YA 1I57A 4QAHA 4HJQA 4OHDA 3QKQA 5HDEA 1BZHA 5BUGA 2I6IA 4KI9A 2A3KA 2VEYA 2F6WA 4ZRTA 1U25A 3ZM2A 4R0TA 1BZCA 5LXQB 2F70A 4CVMA 2F46A 2CM8A 1GWZA 4S0GA 3V0DA 1PTYA 5IBSA 5EHPA 2QEPA 4OHHA 3V0HA 1KAKA 2HC1A 1ONZA 2I4GA 2OC3A 2I1YA 3ZM0A 3EAXA 4CVKA 5K23A 3O4TA 3F9AA 3PS5A 1OEUA 4DGXA 3ZM1A 1T49A 3BLTA 2VEXA 3LJ8A 2NT2A 3QCIA 3GXHA 1G7FA 3MOWA 3S3KA 1ECVA 2ESBA 1C85A 3O4UA 4GRYA 2AM1A 1OETA 4JNBA 2M3VA 2P4DA 5K25A 2AM2A 2R0BA 4RI4A 2QBQA 1J4XA 4GE5A 4YAAA 2I4EA 2F6VA 3QCGA 5KA3A 2OUDA 2G59A 4ERCA 2PI7A 1D5RA 4D3QA 4NWGA 2NZ6A 1NZ7A 2ZMMA 2HVLA 2C46A 2HXPA 1JBWA 2CMCA 2UAGA 3U96A 3V0JA 5KABA 2X5OA 4MBBA 2HNQA 1ZC0A 2CNEA 1Q6MA 2CM2A 1NO6A 1L8GA 2UUPA 4B04A 2H4KA 3QCJA 4GFUA 4BPCA 1FGSA 2PSZA 2Y96A 2B4PA 3V0FA 2FJNA 2VTDA 4D3RA 5BX1A 3AWGA 3ZV2A 2YDUA 2BZLA 2HCMA 1PYNA 2G6ZA 2NTAA 1PA1A 4GS0A 4GWFA 3D1QA 5I6VA 2C7SA 2NT7A 4HRFA 2F71A 1YZ4A 3CWEA 1ZCKA 4GE6A 4HJPA 4YR8B 5A5FA 3AWFA 2QDMA 3I80A 3A5KA 3ZMPA 2CMAA 2JJDA 3ZM3A 2BIJA 1GFYA 1G7GA 3O5XA 2Y67A 1XXVA 2NV5A 2GJTA 4RH5A 2B4OA 2VORA 3QCDA 1G4US 1L8KA 3B7OA 2I6JA 3QCLA 2F6FA 5BZXA 2FJMA 4QDIA 2QBPA 3RO1A 1NL9A 1O5ZA 1FPZA 2A8BA 2J17A 1X24A 3BRHA 4C12A 4I8NA 1U24A 4GFVA 5AWXA 1LYVA 4AZ1A 2P6XA 2PA5A 3PYZA 2I6PA 2WTZA 2JFFA 2MBCA 3D44A 3I36A 4NYHA 3AWEA 1EENA 5BZZA 3D1HA 1WRMA 2CFVA 1Q6JA 4GE2A 1UAGA 1G1HA 4KYRA 3NRSA 3OLRA 2QBRA 1BZJA 4JBCA 3QCHA 2PT0A 1OEMX 1T48A 1C86A 1P3DA 2AHSA 2J16B 3RZ2A 3ZM6A 4WU3A 2Y1OA 4IKCA 3EMUA 1OHCA 3QCEA 4ZN5A 2AZRA 3SR9A 1I9SA 3A5JA 2VEUA 1NWEA 1YGUA 1GQQA 2PBNA 3S4OA 5M43A 5J8RA 1PXHA 1OEOX 1AAXA 1C83A 2I6OA 5K22A 2I3RA 3UAGA 4QBWA 1Q6SA 2WJPA 2B4SA 2I5XA 1VHRA 2H04A 1NWLA 1A5YA 4D3PA 2I75A 2CNGA 1LARA 3D42A 2SHPA 3D9CA 5KA4A 1ZZWA 2QDPA 2HNPA 4BUCA 1EEHA 1OHEA 1PTVA 5KADA 3S3HA 3MVNA 3H2XA 3EB1A 5A5EA 1GG4A 1Q1MA 2VEVA 2GP0A 2RF6A 4RKKA 2E0TA 5KA9A 5K9VA 1QZ0A 2F6TA 3QCMA 2WGPA 5GTJA 1NNYA 3NMEA 4ZI4A 1OHDA 4OHIA 2GC6A 3F81A 5IBMA 4QUNA 2UUOA 4OHLA 2HY3A 2Q05A 3D1OA 4JMKA 1LQFA 3QCFA 2CM3A 3V0EA 3QCCA 1C87A 3V0IA 2B49A 4H34A 1M3GA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1Q6N A;  2QDC A;  3I7Z A;  4Y14 A;  3QCK A;  4Y2E A;  3O4S A;  1G1G A;  4RHG A;  4PVG A;  4WTY A;  2IMG A;  2Q47 A;  2H4V A;  2QCT A;  1R6H A;  2OZ5 A;  2NLK A;  2H03 A;  1YGR A;  3RGO A;  4PYH A;  3O3L A;  4TVV A;  1RXD A;  4R0S A;  2I6M A;  4RI5 A;  4GRZ A;  4BJO A;  3V0G A;  1G4W R;  3QKP A;  1FQ1 A;  1RPM A;  2VEW A;  1SUG A;  3OMH A;  3BM8 A;  2FH7 A;  1KAV A;  2HC2 A;  1YPT A;  1YTN A;  5KA1 A;  4JMJ A;  5EHR A;  3QCB A;  1I9T A;  1EEO A;  4DGP A;  1OEV A;  1XM2 A;  2B4U A;  1P15 A;  3F41 A;  1YFO A;  2CM7 A;  3BLU A;  5KA0 A;  2I3U A;  3RGQ A;  3MOZ A;  1YTW A;  5K9W A;  4WOH A;  1QXK A;  2CJZ A;  3EZZ A;  4QUM A;  1JLN A;  4H1O A;  2BGD A;  3F9B A;  5KA7 A;  2HB1 A;  1FPR A;  3S4E A;  4NND A;  5KAC A;  3EU0 A;  2QCJ A;  3MMJ A;  2BV5 A;  3GXG A;  5KA8 A;  1YTS A;  1T4J A;  2ZN7 A;  2OOQ A;  2CMB A;  2I42 A;  2B3O A;  3N0A A;  1C88 A;  2I4H A;  3S3E A;  2B07 A;  1G1F A;  4NX8 A;  3QCN A;  1PA9 A;  4QBE A;  1ZCL A;  5KA2 A;  2BGE A;  5KAA A;  4R30 A;  4NWF A;  3ZMQ A;  1OES A;  1YWF A;  2F6Z A;  4RH9 A;  1XBO A;  4Z6B A;  4ICZ A;  5K24 A;  4QAP A;  2Y2F A;  1MKP A;  3F99 A;  1JF7 A;  1V3A A;  1YN9 A;  4KYQ A;  1PTU A;  2CNI A;  3CM3 A;  4RDD A;  4OHE A;  1ONY A;  2PQ5 A;  1Q6P A;  1WCH A;  1PH0 A;  1PTT A;  1WAX A;  1U26 A;  4J51 A;  2J16 A;  5MMZ B;  3S3F A;  2H4G A;  1C84 A;  2H02 A;  3M4U A;  3SME A;  1Q6T A;  2GWO A;  2CNH A;  2CNF A;  2QBS A;  1XXP A;  4WU2 A;  2DXP A;  1XRI A;  2F6Y A;  1I57 A;  4QAH A;  4HJQ A;  4OHD A;  3QKQ A;  5HDE A;  1BZH A;  5BUG A;  2I6I A;  4KI9 A;  2A3K A;  2VEY A;  2F6W A;  4ZRT A;  1U25 A;  3ZM2 A;  4R0T A;  1BZC A;  5LXQ B;  2F70 A;  2F46 A;  2CM8 A;  1GWZ A;  4S0G A;  3V0D A;  1PTY A;  5IBS A;  5EHP A;  2QEP A;  4OHH A;  3V0H A;  1KAK A;  2HC1 A;  1ONZ A;  2I4G A;  2OC3 A;  2I1Y A;  3ZM0 A;  3EAX A;  5K23 A;  3O4T A;  3F9A A;  3PS5 A;  1OEU A;  4DGX A;  3ZM1 A;  1T49 A;  3BLT A;  2VEX A;  3LJ8 A;  2NT2 A;  3QCI A;  3GXH A;  1G7F A;  3MOW A;  3S3K A;  1ECV A;  2ESB A;  1C85 A;  3O4U A;  4GRY A;  1OET A;  4JNB A;  2M3V A;  2P4D A;  5K25 A;  2R0B A;  4RI4 A;  2QBQ A;  1J4X A;  4GE5 A;  4YAA A;  2I4E A;  2F6V A;  3QCG A;  5KA3 A;  2OUD A;  2G59 A;  4ERC A;  2PI7 A;  1D5R A;  4D3Q A;  4NWG A;  2NZ6 A;  1NZ7 A;  2ZMM A;  2HVL A;  2C46 A;  2HXP A;  2CMC A;  3U96 A;  3V0J A;  5KAB A;  4MBB A;  2HNQ A;  1ZC0 A;  2CNE A;  1Q6M A;  2CM2 A;  1NO6 A;  1L8G A;  4B04 A;  2H4K A;  3QCJ A;  4GFU A;  4BPC A;  2PSZ A;  2Y96 A;  2B4P A;  3V0F A;  2FJN A;  4D3R A;  5BX1 A;  3AWG A;  3ZV2 A;  2YDU A;  2BZL A;  2HCM A;  1PYN A;  2G6Z A;  2NTA A;  1PA1 A;  4GS0 A;  4GWF A;  3D1Q A;  5I6V A;  2C7S A;  2NT7 A;  4HRF A;  2F71 A;  1YZ4 A;  3CWE A;  1ZCK A;  4GE6 A;  4HJP A;  4YR8 B;  3AWF A;  2QDM A;  3I80 A;  3A5K A;  3ZMP A;  2CMA A;  2JJD A;  3ZM3 A;  2BIJ A;  1GFY A;  1G7G A;  3O5X A;  1XXV A;  2NV5 A;  2GJT A;  4RH5 A;  2B4O A;  3QCD A;  1G4U S;  1L8K A;  3B7O A;  2I6J A;  3QCL A;  2F6F A;  5BZX A;  2FJM A;  3RO1 A;  2QBP A;  1NL9 A;  1FPZ A;  2A8B A;  2J17 A;  1X24 A;  3BRH A;  4I8N A;  1U24 A;  4GFV A;  5AWX A;  1LYV A;  4AZ1 A;  2P6X A;  2PA5 A;  2I6P A;  2MBC A;  3D44 A;  3I36 A;  4NYH A;  3AWE A;  1EEN A;  5BZZ A;  3D1H A;  1WRM A;  2CFV A;  1Q6J A;  4GE2 A;  1G1H A;  4KYR A;  3OLR A;  2QBR A;  1BZJ A;  4JBC A;  3QCH A;  2PT0 A;  1OEM X;  1T48 A;  1C86 A;  2AHS A;  2J16 B;  3RZ2 A;  4WU3 A;  4IKC A;  3EMU A;  1OHC A;  3QCE A;  4ZN5 A;  2AZR A;  3SR9 A;  1I9S A;  3A5J A;  2VEU A;  1NWE A;  1YGU A;  2PBN A;  3S4O A;  5M43 A;  5J8R A;  1PXH A;  1OEO X;  1AAX A;  1C83 A;  2I6O A;  5K22 A;  2I3R A;  4QBW A;  1Q6S A;  2B4S A;  2I5X A;  1VHR A;  2H04 A;  1NWL A;  1A5Y A;  4D3P A;  2I75 A;  2CNG A;  1LAR A;  3D42 A;  2SHP A;  3D9C A;  5KA4 A;  1ZZW A;  2QDP A;  2HNP A;  1OHE A;  1PTV A;  5KAD A;  3S3H A;  3H2X A;  3EB1 A;  1Q1M A;  2VEV A;  2GP0 A;  2RF6 A;  4RKK A;  2E0T A;  5KA9 A;  5K9V A;  1QZ0 A;  2F6T A;  3QCM A;  2WGP A;  5GTJ A;  1NNY A;  3NME A;  4ZI4 A;  1OHD A;  4OHI A;  3F81 A;  5IBM A;  4QUN A;  4OHL A;  2HY3 A;  2Q05 A;  3D1O A;  4JMK A;  1LQF A;  3QCF A;  2CM3 A;  3V0E A;  3QCC A;  1C87 A;  3V0I A;  2B49 A;  4H34 A;  1M3G A; 
#chains in the Genus database with same CATH topology
 1Q6N A;  2QDC A;  3I7Z A;  1GQY A;  4Y14 A;  3QCK A;  4Y2E A;  3O4S A;  1W78 A;  1G1G A;  4RHG A;  1E0D A;  4PVG A;  4WTY A;  2IMG A;  2Q47 A;  2H4V A;  2QCT A;  4BUB A;  1R6H A;  2OZ5 A;  2NLK A;  2H03 A;  1YGR A;  3RGO A;  4PYH A;  3O3L A;  4TVV A;  1RXD A;  4R0S A;  2I6M A;  4RI5 A;  4GRZ A;  4BJO A;  3V0G A;  1G4W R;  3QKP A;  2GC5 A;  1FQ1 A;  3N2A A;  2Y68 A;  1RPM A;  2VEW A;  2VTE A;  1SUG A;  3OMH A;  3BM8 A;  2FH7 A;  2Y66 A;  1KAV A;  2HC2 A;  1YPT A;  1YTN A;  5KA1 A;  4JMJ A;  5EHR A;  3ZL8 A;  3QCB A;  2VOS A;  1I9T A;  1EEO A;  4DGP A;  1OEV A;  1XM2 A;  2B4U A;  1P15 A;  3F41 A;  1YFO A;  2CM7 A;  2XPC A;  1P31 A;  3BLU A;  5KA0 A;  2I3U A;  3RGQ A;  3MOZ A;  1YTW A;  5K9W A;  4WOH A;  2GCA A;  1QXK A;  2CJZ A;  3EZZ A;  4QUM A;  1JLN A;  4H1O A;  1JBV A;  2BGD A;  3F9B A;  5KA7 A;  2HB1 A;  1FPR A;  4CVL A;  3S4E A;  4NND A;  5KAC A;  3EU0 A;  2QCJ A;  3MMJ A;  2BV5 A;  3GXG A;  5KA8 A;  4HV4 A;  1YTS A;  1T4J A;  2ZN7 A;  2OOQ A;  4C13 A;  2CMB A;  2I42 A;  4QF5 A;  2B3O A;  3N0A A;  1C88 A;  1J6U A;  2I4H A;  3S3E A;  2B07 A;  2XJA A;  1G1F A;  4NX8 A;  3QCN A;  1PA9 A;  4QBE A;  1ZCL A;  5KA2 A;  2BGE A;  4ZIY A;  5KAA A;  4R30 A;  1E8C A;  4NWF A;  3ZMQ A;  1OES A;  1YWF A;  2F6Z A;  4RH9 A;  1XBO A;  4Z6B A;  1W7K A;  4ICZ A;  5K24 A;  2GCB A;  4QAP A;  2JFG A;  2Y2F A;  1MKP A;  3F99 A;  1JF7 A;  1V3A A;  3HN7 A;  3ZM5 A;  1YN9 A;  4KYQ A;  4UAG A;  1PTU A;  2CNI A;  3CM3 A;  3LK7 A;  4RDD A;  4OHE A;  1ONY A;  2PQ5 A;  1Q6P A;  1WCH A;  1PH0 A;  2JFH A;  1PTT A;  1WAX A;  1U26 A;  4J51 A;  2J16 A;  5MMZ B;  3S3F A;  2H4G A;  2F00 A;  1C84 A;  2H02 A;  3M4U A;  3SME A;  1Q6T A;  2GWO A;  2CNH A;  2CNF A;  2QBS A;  3QCZ A;  1XXP A;  4WU2 A;  2DXP A;  1XRI A;  2F6Y A;  1I57 A;  4QAH A;  4HJQ A;  4OHD A;  3QKQ A;  5HDE A;  1BZH A;  5BUG A;  2I6I A;  4KI9 A;  2A3K A;  2VEY A;  2F6W A;  4ZRT A;  1U25 A;  3ZM2 A;  4R0T A;  1BZC A;  5LXQ B;  2F70 A;  4CVM A;  2F46 A;  2CM8 A;  1GWZ A;  4S0G A;  3V0D A;  1PTY A;  5IBS A;  5EHP A;  2QEP A;  4OHH A;  3V0H A;  1KAK A;  2HC1 A;  1ONZ A;  2I4G A;  2OC3 A;  2I1Y A;  3ZM0 A;  3EAX A;  4CVK A;  5K23 A;  3O4T A;  3F9A A;  3PS5 A;  1OEU A;  4DGX A;  3ZM1 A;  1T49 A;  3BLT A;  2VEX A;  3LJ8 A;  2NT2 A;  3QCI A;  3GXH A;  1G7F A;  3MOW A;  3S3K A;  1ECV A;  2ESB A;  1C85 A;  3O4U A;  4GRY A;  2AM1 A;  1OET A;  4JNB A;  2M3V A;  2P4D A;  5K25 A;  2AM2 A;  2R0B A;  4RI4 A;  2QBQ A;  1J4X A;  4GE5 A;  4YAA A;  2I4E A;  2F6V A;  3QCG A;  5KA3 A;  2OUD A;  2G59 A;  4ERC A;  2PI7 A;  1D5R A;  4D3Q A;  4NWG A;  2NZ6 A;  1NZ7 A;  2ZMM A;  2HVL A;  2C46 A;  2HXP A;  1JBW A;  2CMC A;  2UAG A;  3U96 A;  3V0J A;  5KAB A;  2X5O A;  4MBB A;  2HNQ A;  1ZC0 A;  2CNE A;  1Q6M A;  2CM2 A;  1NO6 A;  1L8G A;  2UUP A;  4B04 A;  2H4K A;  3QCJ A;  4GFU A;  4BPC A;  1FGS A;  2PSZ A;  2Y96 A;  2B4P A;  3V0F A;  2FJN A;  2VTD A;  4D3R A;  5BX1 A;  3AWG A;  3ZV2 A;  2YDU A;  2BZL A;  2HCM A;  1PYN A;  2G6Z A;  2NTA A;  1PA1 A;  4GS0 A;  4GWF A;  3D1Q A;  5I6V A;  2C7S A;  2NT7 A;  4HRF A;  2F71 A;  1YZ4 A;  3CWE A;  1ZCK A;  4GE6 A;  4HJP A;  4YR8 B;  5A5F A;  3AWF A;  2QDM A;  3I80 A;  3A5K A;  3ZMP A;  2CMA A;  2JJD A;  3ZM3 A;  2BIJ A;  1GFY A;  1G7G A;  3O5X A;  2Y67 A;  1XXV A;  2NV5 A;  2GJT A;  4RH5 A;  2B4O A;  2VOR A;  3QCD A;  1G4U S;  1L8K A;  3B7O A;  2I6J A;  3QCL A;  2F6F A;  5BZX A;  2FJM A;  4QDI A;  2QBP A;  3RO1 A;  1NL9 A;  1O5Z A;  1FPZ A;  2A8B A;  2J17 A;  1X24 A;  3BRH A;  4C12 A;  4I8N A;  1U24 A;  4GFV A;  5AWX A;  1LYV A;  4AZ1 A;  2P6X A;  2PA5 A;  3PYZ A;  2I6P A;  2WTZ A;  2JFF A;  2MBC A;  3D44 A;  3I36 A;  4NYH A;  3AWE A;  1EEN A;  5BZZ A;  3D1H A;  1WRM A;  2CFV A;  1Q6J A;  4GE2 A;  1UAG A;  1G1H A;  4KYR A;  3NRS A;  3OLR A;  2QBR A;  1BZJ A;  4JBC A;  3QCH A;  2PT0 A;  1OEM X;  1T48 A;  1C86 A;  1P3D A;  2AHS A;  2J16 B;  3RZ2 A;  3ZM6 A;  4WU3 A;  2Y1O A;  4IKC A;  3EMU A;  1OHC A;  3QCE A;  4ZN5 A;  2AZR A;  3SR9 A;  1I9S A;  3A5J A;  2VEU A;  1NWE A;  1YGU A;  1GQQ A;  2PBN A;  3S4O A;  5M43 A;  5J8R A;  1PXH A;  1OEO X;  1AAX A;  1C83 A;  2I6O A;  5K22 A;  2I3R A;  3UAG A;  4QBW A;  1Q6S A;  2WJP A;  2B4S A;  2I5X A;  1VHR A;  2H04 A;  1NWL A;  1A5Y A;  4D3P A;  2I75 A;  2CNG A;  1LAR A;  3D42 A;  2SHP A;  3D9C A;  5KA4 A;  1ZZW A;  2QDP A;  2HNP A;  4BUC A;  1EEH A;  1OHE A;  1PTV A;  5KAD A;  3S3H A;  3MVN A;  3H2X A;  3EB1 A;  5A5E A;  1GG4 A;  1Q1M A;  2VEV A;  2GP0 A;  2RF6 A;  4RKK A;  2E0T A;  5KA9 A;  5K9V A;  1QZ0 A;  2F6T A;  3QCM A;  2WGP A;  5GTJ A;  1NNY A;  3NME A;  4ZI4 A;  1OHD A;  4OHI A;  2GC6 A;  3F81 A;  5IBM A;  4QUN A;  2UUO A;  4OHL A;  2HY3 A;  2Q05 A;  3D1O A;  4JMK A;  1LQF A;  3QCF A;  2CM3 A;  3V0E A;  3QCC A;  1C87 A;  3V0I A;  2B49 A;  4H34 A;  1M3G A; 
#chains in the Genus database with same CATH homology
 1Q6N A;  2QDC A;  3I7Z A;  4Y14 A;  3QCK A;  4Y2E A;  3O4S A;  1G1G A;  4RHG A;  4PVG A;  4WTY A;  2IMG A;  2Q47 A;  2H4V A;  2QCT A;  1R6H A;  2OZ5 A;  2NLK A;  2H03 A;  1YGR A;  3RGO A;  4PYH A;  3O3L A;  4TVV A;  1RXD A;  4R0S A;  2I6M A;  4RI5 A;  4GRZ A;  4BJO A;  3V0G A;  1G4W R;  3QKP A;  1FQ1 A;  1RPM A;  2VEW A;  1SUG A;  3OMH A;  3BM8 A;  2FH7 A;  1KAV A;  2HC2 A;  1YPT A;  1YTN A;  5KA1 A;  4JMJ A;  5EHR A;  3QCB A;  1I9T A;  1EEO A;  4DGP A;  1OEV A;  1XM2 A;  2B4U A;  1P15 A;  3F41 A;  1YFO A;  2CM7 A;  3BLU A;  5KA0 A;  2I3U A;  3RGQ A;  3MOZ A;  1YTW A;  5K9W A;  4WOH A;  1QXK A;  2CJZ A;  3EZZ A;  4QUM A;  1JLN A;  4H1O A;  2BGD A;  3F9B A;  5KA7 A;  2HB1 A;  1FPR A;  3S4E A;  4NND A;  5KAC A;  3EU0 A;  2QCJ A;  3MMJ A;  2BV5 A;  3GXG A;  5KA8 A;  1YTS A;  1T4J A;  2ZN7 A;  2OOQ A;  2CMB A;  2I42 A;  2B3O A;  3N0A A;  1C88 A;  2I4H A;  3S3E A;  2B07 A;  1G1F A;  4NX8 A;  3QCN A;  1PA9 A;  4QBE A;  1ZCL A;  5KA2 A;  2BGE A;  5KAA A;  4R30 A;  4NWF A;  3ZMQ A;  1OES A;  1YWF A;  2F6Z A;  4RH9 A;  1XBO A;  4Z6B A;  4ICZ A;  5K24 A;  4QAP A;  2Y2F A;  1MKP A;  3F99 A;  1JF7 A;  1V3A A;  1YN9 A;  4KYQ A;  1PTU A;  2CNI A;  3CM3 A;  4RDD A;  4OHE A;  1ONY A;  2PQ5 A;  1Q6P A;  1WCH A;  1PH0 A;  1PTT A;  1WAX A;  1U26 A;  4J51 A;  2J16 A;  5MMZ B;  3S3F A;  2H4G A;  1C84 A;  2H02 A;  3M4U A;  3SME A;  1Q6T A;  2GWO A;  2CNH A;  2CNF A;  2QBS A;  1XXP A;  4WU2 A;  2DXP A;  1XRI A;  2F6Y A;  1I57 A;  4QAH A;  4HJQ A;  4OHD A;  3QKQ A;  5HDE A;  1BZH A;  5BUG A;  2I6I A;  4KI9 A;  2A3K A;  2VEY A;  2F6W A;  4ZRT A;  1U25 A;  3ZM2 A;  4R0T A;  1BZC A;  5LXQ B;  2F70 A;  2F46 A;  2CM8 A;  1GWZ A;  4S0G A;  3V0D A;  1PTY A;  5IBS A;  5EHP A;  2QEP A;  4OHH A;  3V0H A;  1KAK A;  2HC1 A;  1ONZ A;  2I4G A;  2OC3 A;  2I1Y A;  3ZM0 A;  3EAX A;  5K23 A;  3O4T A;  3F9A A;  3PS5 A;  1OEU A;  4DGX A;  3ZM1 A;  1T49 A;  3BLT A;  2VEX A;  3LJ8 A;  2NT2 A;  3QCI A;  3GXH A;  1G7F A;  3MOW A;  3S3K A;  1ECV A;  2ESB A;  1C85 A;  3O4U A;  4GRY A;  1OET A;  4JNB A;  2M3V A;  2P4D A;  5K25 A;  2R0B A;  4RI4 A;  2QBQ A;  1J4X A;  4GE5 A;  4YAA A;  2I4E A;  2F6V A;  3QCG A;  5KA3 A;  2OUD A;  2G59 A;  4ERC A;  2PI7 A;  1D5R A;  4D3Q A;  4NWG A;  2NZ6 A;  1NZ7 A;  2ZMM A;  2HVL A;  2C46 A;  2HXP A;  2CMC A;  3U96 A;  3V0J A;  5KAB A;  4MBB A;  2HNQ A;  1ZC0 A;  2CNE A;  1Q6M A;  2CM2 A;  1NO6 A;  1L8G A;  4B04 A;  2H4K A;  3QCJ A;  4GFU A;  4BPC A;  2PSZ A;  2Y96 A;  2B4P A;  3V0F A;  2FJN A;  4D3R A;  5BX1 A;  3AWG A;  3ZV2 A;  2YDU A;  2BZL A;  2HCM A;  1PYN A;  2G6Z A;  2NTA A;  1PA1 A;  4GS0 A;  4GWF A;  3D1Q A;  5I6V A;  2C7S A;  2NT7 A;  4HRF A;  2F71 A;  1YZ4 A;  3CWE A;  1ZCK A;  4GE6 A;  4HJP A;  4YR8 B;  3AWF A;  2QDM A;  3I80 A;  3A5K A;  3ZMP A;  2CMA A;  2JJD A;  3ZM3 A;  2BIJ A;  1GFY A;  1G7G A;  3O5X A;  1XXV A;  2NV5 A;  2GJT A;  4RH5 A;  2B4O A;  3QCD A;  1G4U S;  1L8K A;  3B7O A;  2I6J A;  3QCL A;  2F6F A;  5BZX A;  2FJM A;  3RO1 A;  2QBP A;  1NL9 A;  1FPZ A;  2A8B A;  2J17 A;  1X24 A;  3BRH A;  4I8N A;  1U24 A;  4GFV A;  5AWX A;  1LYV A;  4AZ1 A;  2P6X A;  2PA5 A;  2I6P A;  2MBC A;  3D44 A;  3I36 A;  4NYH A;  3AWE A;  1EEN A;  5BZZ A;  3D1H A;  1WRM A;  2CFV A;  1Q6J A;  4GE2 A;  1G1H A;  4KYR A;  3OLR A;  2QBR A;  1BZJ A;  4JBC A;  3QCH A;  2PT0 A;  1OEM X;  1T48 A;  1C86 A;  2AHS A;  2J16 B;  3RZ2 A;  4WU3 A;  4IKC A;  3EMU A;  1OHC A;  3QCE A;  4ZN5 A;  2AZR A;  3SR9 A;  1I9S A;  3A5J A;  2VEU A;  1NWE A;  1YGU A;  2PBN A;  3S4O A;  5M43 A;  5J8R A;  1PXH A;  1OEO X;  1AAX A;  1C83 A;  2I6O A;  5K22 A;  2I3R A;  4QBW A;  1Q6S A;  2B4S A;  2I5X A;  1VHR A;  2H04 A;  1NWL A;  1A5Y A;  4D3P A;  2I75 A;  2CNG A;  1LAR A;  3D42 A;  2SHP A;  3D9C A;  5KA4 A;  1ZZW A;  2QDP A;  2HNP A;  1OHE A;  1PTV A;  5KAD A;  3S3H A;  3H2X A;  3EB1 A;  1Q1M A;  2VEV A;  2GP0 A;  2RF6 A;  4RKK A;  2E0T A;  5KA9 A;  5K9V A;  1QZ0 A;  2F6T A;  3QCM A;  2WGP A;  5GTJ A;  1NNY A;  3NME A;  4ZI4 A;  1OHD A;  4OHI A;  3F81 A;  5IBM A;  4QUN A;  4OHL A;  2HY3 A;  2Q05 A;  3D1O A;  4JMK A;  1LQF A;  3QCF A;  2CM3 A;  3V0E A;  3QCC A;  1C87 A;  3V0I A;  2B49 A;  4H34 A;  1M3G A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4GE5A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations