4QBEA

The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
298
structure length
298
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQSADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 97
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4qbeA00
2BIJA 3ZM3A 1YTWA 4GRZA 1Q6PA 1C84A 3N0AA 3EMUA 1PXHA 4I8NA 2BZLA 4YAAA 4BJOA 3S3HA 1C88A 4WU3A 2CNEA 2ESBA 3LJ8A 5MMZB 1XXPA 4J51A 3S4OA 5K24A 2HNPA 1YTSA 1YWFA 1VHRA 2QBSA 1Q6MA 3ZV2A 4QAHA 1OHCA 4RHGA 3ZMPA 3BRHA 1NWEA 1Q6JA 4KYQA 5J8RA 1V3AA 3QKPA 2OZ5A 4D3PA 3ZM1A 2A3KA 4NNDA 4QUNA 2CFVA 4OHLA 4NYHA 4WTYA 4Y2EA 2H4VA 1KAVA 3OMHA 2QBRA 3D9CA 2CM8A 2F6YA 4R30A 1XRIA 2SHPA 1YGRA 3EB1A 4OHIA 1QZ0A 2PA5A 3ZM0A 2BV5A 2QBQA 1ZCLA 3S3KA 3CWEA 2B4PA 2QDMA 1U24A 1JF7A 2VEUA 3QCCA 4S0GA 5I6VA 2FJMA 2AHSA 2CM2A 5K23A 4YR8B 1LYVA 4TVVA 2HNQA 1BZCA 1NL9A 3QCDA 2Y96A 4RI4A 3A5KA 3RO1A 2QEPA 4ZRTA 3U96A 4GWFA 1MKPA 2F46A 5HDEA 4RDDA 4ZI4A 2F71A 2NZ6A 4QBWA 4R0SA 1Q6SA 4GS0A 4QBEA 1FQ1A 1T49A 3O4UA 1WAXA 1OESA 2F6TA 4PYHA 2CNFA 5EHPA 2ZMMA 2FJNA 2YDUA 4MBBA 1U25A 1LQFA 3H2XA 1OEOX 1G1FA 4H34A 3D1QA 3S4EA 3D44A 2NTAA 3ZMQA 2I1YA 2B49A 2J16A 2NV5A 2HC2A 1L8KA 5KACA 2MBCA 1PTVA 1Q6NA 2I6OA 4QUMA 5AWXA 1BZHA 2CNIA 3F41A 2B4SA 2CMCA 3D1OA 1PYNA 3RGQA 1OETA 3MOZA 4GE5A 2BGDA 3QCLA 2C7SA 2GP0A 2FH7A 4D3QA 2PSZA 2I4EA 4GE6A 3RZ2A 1J4XA 3PS5A 1YZ4A 2HC1A 2I4HA 3OLRA 2F6ZA 3QCHA 2H04A 3V0JA 3O4TA 2R0BA 3F9AA 2F6WA 1G7FA 4ICZA 2G6ZA 1G1HA 1XXVA 3BLTA 3F99A 1YGUA 3EU0A 1ONYA 5M43A 1T48A 2NT7A 1C85A 4JNBA 3AWFA 1PA1A 3B7OA 1X24A 2CNGA 2RF6A 2IMGA 4R0TA 3S3EA 3F9BA 1XBOA 3QCMA 3BM8A 5KADA 3MMJA 2CJZA 3S3FA 2WGPA 2OC3A 3D42A 1ZC0A 3V0FA 2Q05A 1OEVA 4IKCA 3SMEA 5K9WA 1ONZA 4PVGA 2P4DA 2QDPA 2F6VA 4JMJA 5IBSA 1PH0A 1EENA 4OHDA 4NWFA 3GXHA 1OHEA 3MOWA 1FPRA 5KA4A 2ZN7A 3NMEA 3BLUA 5K9VA 2I6IA 1G4WR 2CNHA 1G7GA 4GRYA 5KA3A 3I7ZA 2CMAA 4RH5A 1OEMX 4JBCA 1NWLA 2PI7A 5IBMA 1G1GA 4OHEA 1P15A 1A5YA 2H4GA 1SUGA 1EEOA 3QCJA 1QXKA 2AZRA 3QCFA 3SR9A 2I5XA 2VEVA 3EZZA 1PTUA 3RGOA 5KA1A 2VEWA 3QCIA 1T4JA 2HVLA 2QCTA 3AWEA 5EHRA 2J17A 5KABA 2QBPA 4ZN5A 1YN9A 4RH9A 1PA9A 2E0TA 3QCBA 1YFOA 1C83A 5KA2A 2QDCA 5KA7A 2Y2FA 2NT2A 3ZM2A 4QAPA 3QCNA 1M3GA 3V0GA 1C86A 2HY3A 2BGEA 1NNYA 2M3VA 3V0IA 4KI9A 2PQ5A 3QCGA 2I6PA 1BZJA 5BX1A 4BPCA 2J16B 1XM2A 4NWGA 5BUGA 4RKKA 2G59A 4JMKA 3F81A 1L8GA 2B4UA 2QCJA 1I9SA 1OEUA 2OOQA 3M4UA 1ZCKA 3V0EA 3GXGA 4GFVA 1PTYA 2C46A 3O3LA 3QKQA 2CM3A 3O5XA 1NZ7A 3AWGA 3D1HA 3I36A 2NLKA 1D5RA 2P6XA 4RI5A 5BZXA 3A5JA 2HB1A 2HXPA 2I42A 2VEYA 5BZZA 1C87A 2DXPA 2F6FA 3O4SA 1AAXA 2CM7A 1YTNA 2JJDA 4H1OA 2OUDA 2GJTA 1Q1MA 4Z6BA 4B04A 4AZ1A 4WOHA 4GE2A 2H03A 2I75A 3V0DA 5KAAA 1GWZA 1LARA 1ZZWA 5KA9A 4HJQA 1FPZA 1RXDA 5K25A 5LXQB 2GWOA 1ECVA 1YPTA 1WRMA 1KAKA 4OHHA 3QCKA 2H4KA 2I4GA 4Y14A 5KA0A 1I57A 1I9TA 1OHDA 1Q6TA 3EAXA 5K22A 4ERCA 4KYRA 4WU2A 2VEXA 4HRFA 4DGPA 2CMBA 5KA8A 2B3OA 1G4US 2F70A 4NX8A 1WCHA 2B07A 1RPMA 2H02A 5GTJA 2PT0A 4GFUA 2A8BA 2I6JA 1JLNA 3QCEA 2I3RA 3CM3A 2I3UA 1NO6A 1R6HA 1PTTA 3I80A 1U26A 4HJPA 2Q47A 3V0HA 2PBNA 4D3RA 2I6MA 4DGXA 2B4OA 2HCMA 1GFYA
chains in the Genus database with same CATH superfamily
2BIJA 3ZM3A 1YTWA 3QCZA 4GRZA 1Q6PA 1C84A 3N0AA 3EMUA 1PXHA 4I8NA 2BZLA 4YAAA 4BJOA 2GCAA 4C13A 4CVKA 3S3HA 1C88A 4WU3A 2CNEA 2ESBA 3LJ8A 5MMZB 1XXPA 4J51A 3S4OA 5K24A 2HNPA 4QDIA 1YTSA 1YWFA 1VHRA 2QBSA 1GG4A 1Q6MA 3ZV2A 4QAHA 1OHCA 4RHGA 3ZMPA 3BRHA 1NWEA 1GQQA 1Q6JA 4KYQA 1E8CA 5J8RA 1V3AA 3QKPA 2OZ5A 4D3PA 3ZM1A 2A3KA 1J6UA 4NNDA 4QUNA 2CFVA 4OHLA 4NYHA 4WTYA 4Y2EA 1O5ZA 2H4VA 1KAVA 3OMHA 2QBRA 3D9CA 2CM8A 2F6YA 4R30A 1XRIA 2SHPA 1YGRA 3EB1A 4OHIA 1QZ0A 2PA5A 2F00A 3ZM0A 2BV5A 2QBQA 1ZCLA 3S3KA 3CWEA 2B4PA 2QDMA 1U24A 1JF7A 1UAGA 2VEUA 3QCCA 4S0GA 5I6VA 2FJMA 2AHSA 2CM2A 5K23A 4YR8B 2AM2A 1LYVA 4TVVA 2HNQA 1BZCA 1W7KA 1NL9A 3QCDA 2Y96A 4RI4A 3A5KA 3RO1A 1FGSA 2QEPA 2WTZA 3NRSA 4ZRTA 3U96A 3HN7A 4GWFA 1MKPA 2F46A 5HDEA 4RDDA 4ZI4A 2F71A 2NZ6A 4QBWA 4R0SA 1Q6SA 4GS0A 5A5FA 2WJPA 4QBEA 4CVMA 1FQ1A 5A5EA 1T49A 3O4UA 1WAXA 1OESA 2F6TA 4PYHA 3ZM6A 2CNFA 5EHPA 2ZMMA 2FJNA 2YDUA 4MBBA 1U25A 1LQFA 3H2XA 1OEOX 1G1FA 4H34A 3D1QA 3S4EA 2Y67A 3D44A 2NTAA 3ZMQA 2I1YA 2B49A 2J16A 2NV5A 2HC2A 1L8KA 5KACA 2MBCA 1PTVA 1Q6NA 2I6OA 4QUMA 5AWXA 1BZHA 2CNIA 4CVLA 3F41A 2B4SA 2CMCA 2UAGA 3D1OA 3MVNA 3UAGA 1PYNA 3RGQA 1OETA 2AM1A 3MOZA 4BUCA 4GE5A 2BGDA 3QCLA 2C7SA 2GP0A 2FH7A 4D3QA 2PSZA 2I4EA 4GE6A 3RZ2A 1J4XA 3PS5A 1YZ4A 2HC1A 2Y66A 2I4HA 3OLRA 2F6ZA 3QCHA 4HV4A 3PYZA 2H04A 3ZM5A 3V0JA 3O4TA 2R0BA 3F9AA 2F6WA 1G7FA 4ICZA 2G6ZA 1G1HA 1XXVA 3ZL8A 3BLTA 3F99A 1YGUA 2XPCA 3EU0A 1ONYA 1JBVA 5M43A 1T48A 2X5OA 2NT7A 1C85A 4JNBA 3AWFA 1PA1A 1W78A 3B7OA 1X24A 2CNGA 2RF6A 2IMGA 4R0TA 3S3EA 3F9BA 1XBOA 3QCMA 3BM8A 5KADA 3MMJA 2CJZA 3S3FA 2WGPA 2OC3A 3D42A 1ZC0A 3V0FA 2Q05A 1OEVA 4IKCA 3SMEA 1E0DA 5K9WA 1ONZA 2JFGA 4PVGA 2P4DA 2QDPA 2F6VA 4JMJA 5IBSA 1PH0A 1EENA 4OHDA 4NWFA 3GXHA 1OHEA 3MOWA 1FPRA 5KA4A 2ZN7A 3NMEA 3BLUA 5K9VA 2I6IA 1G4WR 2CNHA 1G7GA 4GRYA 5KA3A 3I7ZA 2CMAA 4RH5A 1OEMX 4JBCA 1NWLA 2GC5A 2PI7A 5IBMA 2VOSA 1G1GA 3LK7A 2VORA 4OHEA 1P15A 1A5YA 2H4GA 1SUGA 1EEOA 3QCJA 1QXKA 1EEHA 2AZRA 3QCFA 3SR9A 2I5XA 2VEVA 1JBWA 3EZZA 1PTUA 3RGOA 5KA1A 2VEWA 3QCIA 2Y68A 1T4JA 2HVLA 2QCTA 3AWEA 5EHRA 2J17A 5KABA 2QBPA 4ZIYA 2UUPA 4ZN5A 1YN9A 4RH9A 1PA9A 2E0TA 2VTEA 3QCBA 2Y1OA 1YFOA 4BUBA 1C83A 5KA2A 2QDCA 5KA7A 4QF5A 2Y2FA 2NT2A 3ZM2A 4QAPA 3QCNA 1M3GA 3V0GA 1C86A 2HY3A 2BGEA 1NNYA 2M3VA 2VTDA 3V0IA 4KI9A 2PQ5A 3QCGA 2I6PA 1BZJA 1P31A 5BX1A 4BPCA 2J16B 1XM2A 4NWGA 5BUGA 4RKKA 2G59A 4JMKA 3F81A 1L8GA 2B4UA 2QCJA 1I9SA 1OEUA 2OOQA 3M4UA 1ZCKA 2GCBA 3V0EA 3GXGA 4GFVA 1PTYA 2C46A 3O3LA 3QKQA 2CM3A 3O5XA 1NZ7A 3AWGA 3D1HA 3I36A 2NLKA 2GC6A 2UUOA 1D5RA 2P6XA 4RI5A 5BZXA 3A5JA 2HB1A 2HXPA 2I42A 2VEYA 5BZZA 1C87A 2DXPA 2F6FA 3O4SA 2XJAA 1AAXA 2CM7A 1YTNA 2JJDA 4H1OA 2OUDA 2GJTA 1Q1MA 4Z6BA 4B04A 4AZ1A 4WOHA 4GE2A 2H03A 2I75A 3V0DA 5KAAA 1GWZA 1LARA 1ZZWA 5KA9A 1GQYA 4HJQA 1FPZA 1RXDA 5K25A 5LXQB 2GWOA 1ECVA 1YPTA 3N2AA 1WRMA 1KAKA 4OHHA 3QCKA 2H4KA 2I4GA 4Y14A 5KA0A 2JFHA 1I57A 1I9TA 1OHDA 1Q6TA 3EAXA 5K22A 4ERCA 4KYRA 4C12A 4WU2A 2VEXA 4HRFA 4DGPA 2CMBA 5KA8A 1P3DA 2B3OA 1G4US 2F70A 4NX8A 1WCHA 2B07A 1RPMA 2H02A 5GTJA 2PT0A 4GFUA 2A8BA 2I6JA 4UAGA 1JLNA 2JFFA 3QCEA 2I3RA 3CM3A 2I3UA 1NO6A 1R6HA 1PTTA 3I80A 1U26A 4HJPA 2Q47A 3V0HA 2PBNA 4D3RA 2I6MA 4DGXA 2B4OA 2HCMA 1GFYA
chains in the Genus database with same CATH topology
2BIJA 3ZM3A 1YTWA 4GRZA 1Q6PA 1C84A 3N0AA 3EMUA 1PXHA 4I8NA 2BZLA 4YAAA 4BJOA 3S3HA 1C88A 4WU3A 2CNEA 2ESBA 3LJ8A 5MMZB 1XXPA 4J51A 3S4OA 5K24A 2HNPA 1YTSA 1YWFA 1VHRA 2QBSA 1Q6MA 3ZV2A 4QAHA 1OHCA 4RHGA 3ZMPA 3BRHA 1NWEA 1Q6JA 4KYQA 5J8RA 1V3AA 3QKPA 2OZ5A 4D3PA 3ZM1A 2A3KA 4NNDA 4QUNA 2CFVA 4OHLA 4NYHA 4WTYA 4Y2EA 2H4VA 1KAVA 3OMHA 2QBRA 3D9CA 2CM8A 2F6YA 4R30A 1XRIA 2SHPA 1YGRA 3EB1A 4OHIA 1QZ0A 2PA5A 3ZM0A 2BV5A 2QBQA 1ZCLA 3S3KA 3CWEA 2B4PA 2QDMA 1U24A 1JF7A 2VEUA 3QCCA 4S0GA 5I6VA 2FJMA 2AHSA 2CM2A 5K23A 4YR8B 1LYVA 4TVVA 2HNQA 1BZCA 1NL9A 3QCDA 2Y96A 4RI4A 3A5KA 3RO1A 2QEPA 4ZRTA 3U96A 4GWFA 1MKPA 2F46A 5HDEA 4RDDA 4ZI4A 2F71A 2NZ6A 4QBWA 4R0SA 1Q6SA 4GS0A 4QBEA 1FQ1A 1T49A 3O4UA 1WAXA 1OESA 2F6TA 4PYHA 2CNFA 5EHPA 2ZMMA 2FJNA 2YDUA 4MBBA 1U25A 1LQFA 3H2XA 1OEOX 1G1FA 4H34A 3D1QA 3S4EA 3D44A 2NTAA 3ZMQA 2I1YA 2B49A 2J16A 2NV5A 2HC2A 1L8KA 5KACA 2MBCA 1PTVA 1Q6NA 2I6OA 4QUMA 5AWXA 1BZHA 2CNIA 3F41A 2B4SA 2CMCA 3D1OA 1PYNA 3RGQA 1OETA 3MOZA 4GE5A 2BGDA 3QCLA 2C7SA 2GP0A 2FH7A 4D3QA 2PSZA 2I4EA 4GE6A 3RZ2A 1J4XA 3PS5A 1YZ4A 2HC1A 2I4HA 3OLRA 2F6ZA 3QCHA 2H04A 3V0JA 3O4TA 2R0BA 3F9AA 2F6WA 1G7FA 4ICZA 2G6ZA 1G1HA 1XXVA 3BLTA 3F99A 1YGUA 3EU0A 1ONYA 5M43A 1T48A 2NT7A 1C85A 4JNBA 3AWFA 1PA1A 3B7OA 1X24A 2CNGA 2RF6A 2IMGA 4R0TA 3S3EA 3F9BA 1XBOA 3QCMA 3BM8A 5KADA 3MMJA 2CJZA 3S3FA 2WGPA 2OC3A 3D42A 1ZC0A 3V0FA 2Q05A 1OEVA 4IKCA 3SMEA 5K9WA 1ONZA 4PVGA 2P4DA 2QDPA 2F6VA 4JMJA 5IBSA 1PH0A 1EENA 4OHDA 4NWFA 3GXHA 1OHEA 3MOWA 1FPRA 5KA4A 2ZN7A 3NMEA 3BLUA 5K9VA 2I6IA 1G4WR 2CNHA 1G7GA 4GRYA 5KA3A 3I7ZA 2CMAA 4RH5A 1OEMX 4JBCA 1NWLA 2PI7A 5IBMA 1G1GA 4OHEA 1P15A 1A5YA 2H4GA 1SUGA 1EEOA 3QCJA 1QXKA 2AZRA 3QCFA 3SR9A 2I5XA 2VEVA 3EZZA 1PTUA 3RGOA 5KA1A 2VEWA 3QCIA 1T4JA 2HVLA 2QCTA 3AWEA 5EHRA 2J17A 5KABA 2QBPA 4ZN5A 1YN9A 4RH9A 1PA9A 2E0TA 3QCBA 1YFOA 1C83A 5KA2A 2QDCA 5KA7A 2Y2FA 2NT2A 3ZM2A 4QAPA 3QCNA 1M3GA 3V0GA 1C86A 2HY3A 2BGEA 1NNYA 2M3VA 3V0IA 4KI9A 2PQ5A 3QCGA 2I6PA 1BZJA 5BX1A 4BPCA 2J16B 1XM2A 4NWGA 5BUGA 4RKKA 2G59A 4JMKA 3F81A 1L8GA 2B4UA 2QCJA 1I9SA 1OEUA 2OOQA 3M4UA 1ZCKA 3V0EA 3GXGA 4GFVA 1PTYA 2C46A 3O3LA 3QKQA 2CM3A 3O5XA 1NZ7A 3AWGA 3D1HA 3I36A 2NLKA 1D5RA 2P6XA 4RI5A 5BZXA 3A5JA 2HB1A 2HXPA 2I42A 2VEYA 5BZZA 1C87A 2DXPA 2F6FA 3O4SA 1AAXA 2CM7A 1YTNA 2JJDA 4H1OA 2OUDA 2GJTA 1Q1MA 4Z6BA 4B04A 4AZ1A 4WOHA 4GE2A 2H03A 2I75A 3V0DA 5KAAA 1GWZA 1LARA 1ZZWA 5KA9A 4HJQA 1FPZA 1RXDA 5K25A 5LXQB 2GWOA 1ECVA 1YPTA 1WRMA 1KAKA 4OHHA 3QCKA 2H4KA 2I4GA 4Y14A 5KA0A 1I57A 1I9TA 1OHDA 1Q6TA 3EAXA 5K22A 4ERCA 4KYRA 4WU2A 2VEXA 4HRFA 4DGPA 2CMBA 5KA8A 2B3OA 1G4US 2F70A 4NX8A 1WCHA 2B07A 1RPMA 2H02A 5GTJA 2PT0A 4GFUA 2A8BA 2I6JA 1JLNA 3QCEA 2I3RA 3CM3A 2I3UA 1NO6A 1R6HA 1PTTA 3I80A 1U26A 4HJPA 2Q47A 3V0HA 2PBNA 4D3RA 2I6MA 4DGXA 2B4OA 2HCMA 1GFYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BIJ A;  3ZM3 A;  1YTW A;  4GRZ A;  1Q6P A;  1C84 A;  3N0A A;  3EMU A;  1PXH A;  4I8N A;  2BZL A;  4YAA A;  4BJO A;  3S3H A;  1C88 A;  4WU3 A;  2CNE A;  2ESB A;  3LJ8 A;  5MMZ B;  1XXP A;  4J51 A;  3S4O A;  5K24 A;  2HNP A;  1YTS A;  1YWF A;  1VHR A;  2QBS A;  1Q6M A;  3ZV2 A;  4QAH A;  1OHC A;  4RHG A;  3ZMP A;  3BRH A;  1NWE A;  1Q6J A;  4KYQ A;  5J8R A;  1V3A A;  3QKP A;  2OZ5 A;  4D3P A;  3ZM1 A;  2A3K A;  4NND A;  4QUN A;  2CFV A;  4OHL A;  4NYH A;  4WTY A;  4Y2E A;  2H4V A;  1KAV A;  3OMH A;  2QBR A;  3D9C A;  2CM8 A;  2F6Y A;  4R30 A;  1XRI A;  2SHP A;  1YGR A;  3EB1 A;  4OHI A;  1QZ0 A;  2PA5 A;  3ZM0 A;  2BV5 A;  2QBQ A;  1ZCL A;  3S3K A;  3CWE A;  2B4P A;  2QDM A;  1U24 A;  1JF7 A;  2VEU A;  3QCC A;  4S0G A;  5I6V A;  2FJM A;  2AHS A;  2CM2 A;  5K23 A;  4YR8 B;  1LYV A;  4TVV A;  2HNQ A;  1BZC A;  1NL9 A;  3QCD A;  2Y96 A;  4RI4 A;  3A5K A;  3RO1 A;  2QEP A;  4ZRT A;  3U96 A;  4GWF A;  1MKP A;  2F46 A;  5HDE A;  4RDD A;  4ZI4 A;  2F71 A;  2NZ6 A;  4QBW A;  4R0S A;  1Q6S A;  4GS0 A;  4QBE A;  1FQ1 A;  1T49 A;  3O4U A;  1WAX A;  1OES A;  2F6T A;  4PYH A;  2CNF A;  5EHP A;  2ZMM A;  2FJN A;  2YDU A;  4MBB A;  1U25 A;  1LQF A;  3H2X A;  1OEO X;  1G1F A;  4H34 A;  3D1Q A;  3S4E A;  3D44 A;  2NTA A;  3ZMQ A;  2I1Y A;  2B49 A;  2J16 A;  2NV5 A;  2HC2 A;  1L8K A;  5KAC A;  2MBC A;  1PTV A;  1Q6N A;  2I6O A;  4QUM A;  5AWX A;  1BZH A;  2CNI A;  3F41 A;  2B4S A;  2CMC A;  3D1O A;  1PYN A;  3RGQ A;  1OET A;  3MOZ A;  4GE5 A;  2BGD A;  3QCL A;  2C7S A;  2GP0 A;  2FH7 A;  4D3Q A;  2PSZ A;  2I4E A;  4GE6 A;  3RZ2 A;  1J4X A;  3PS5 A;  1YZ4 A;  2HC1 A;  2I4H A;  3OLR A;  2F6Z A;  3QCH A;  2H04 A;  3V0J A;  3O4T A;  2R0B A;  3F9A A;  2F6W A;  1G7F A;  4ICZ A;  2G6Z A;  1G1H A;  1XXV A;  3BLT A;  3F99 A;  1YGU A;  3EU0 A;  1ONY A;  5M43 A;  1T48 A;  2NT7 A;  1C85 A;  4JNB A;  3AWF A;  1PA1 A;  3B7O A;  1X24 A;  2CNG A;  2RF6 A;  2IMG A;  4R0T A;  3S3E A;  3F9B A;  1XBO A;  3QCM A;  3BM8 A;  5KAD A;  3MMJ A;  2CJZ A;  3S3F A;  2WGP A;  2OC3 A;  3D42 A;  1ZC0 A;  3V0F A;  2Q05 A;  1OEV A;  4IKC A;  3SME A;  5K9W A;  1ONZ A;  4PVG A;  2P4D A;  2QDP A;  2F6V A;  4JMJ A;  5IBS A;  1PH0 A;  1EEN A;  4OHD A;  4NWF A;  3GXH A;  1OHE A;  3MOW A;  1FPR A;  5KA4 A;  2ZN7 A;  3NME A;  3BLU A;  5K9V A;  2I6I A;  1G4W R;  2CNH A;  1G7G A;  4GRY A;  5KA3 A;  3I7Z A;  2CMA A;  4RH5 A;  1OEM X;  4JBC A;  1NWL A;  2PI7 A;  5IBM A;  1G1G A;  4OHE A;  1P15 A;  1A5Y A;  2H4G A;  1SUG A;  1EEO A;  3QCJ A;  1QXK A;  2AZR A;  3QCF A;  3SR9 A;  2I5X A;  2VEV A;  3EZZ A;  1PTU A;  3RGO A;  5KA1 A;  2VEW A;  3QCI A;  1T4J A;  2HVL A;  2QCT A;  3AWE A;  5EHR A;  2J17 A;  5KAB A;  2QBP A;  4ZN5 A;  1YN9 A;  4RH9 A;  1PA9 A;  2E0T A;  3QCB A;  1YFO A;  1C83 A;  5KA2 A;  2QDC A;  5KA7 A;  2Y2F A;  2NT2 A;  3ZM2 A;  4QAP A;  3QCN A;  1M3G A;  3V0G A;  1C86 A;  2HY3 A;  2BGE A;  1NNY A;  2M3V A;  3V0I A;  4KI9 A;  2PQ5 A;  3QCG A;  2I6P A;  1BZJ A;  5BX1 A;  4BPC A;  2J16 B;  1XM2 A;  4NWG A;  5BUG A;  4RKK A;  2G59 A;  4JMK A;  3F81 A;  1L8G A;  2B4U A;  2QCJ A;  1I9S A;  1OEU A;  2OOQ A;  3M4U A;  1ZCK A;  3V0E A;  3GXG A;  4GFV A;  1PTY A;  2C46 A;  3O3L A;  3QKQ A;  2CM3 A;  3O5X A;  1NZ7 A;  3AWG A;  3D1H A;  3I36 A;  2NLK A;  1D5R A;  2P6X A;  4RI5 A;  5BZX A;  3A5J A;  2HB1 A;  2HXP A;  2I42 A;  2VEY A;  5BZZ A;  1C87 A;  2DXP A;  2F6F A;  3O4S A;  1AAX A;  2CM7 A;  1YTN A;  2JJD A;  4H1O A;  2OUD A;  2GJT A;  1Q1M A;  4Z6B A;  4B04 A;  4AZ1 A;  4WOH A;  4GE2 A;  2H03 A;  2I75 A;  3V0D A;  5KAA A;  1GWZ A;  1LAR A;  1ZZW A;  5KA9 A;  4HJQ A;  1FPZ A;  1RXD A;  5K25 A;  5LXQ B;  2GWO A;  1ECV A;  1YPT A;  1WRM A;  1KAK A;  4OHH A;  3QCK A;  2H4K A;  2I4G A;  4Y14 A;  5KA0 A;  1I57 A;  1I9T A;  1OHD A;  1Q6T A;  3EAX A;  5K22 A;  4ERC A;  4KYR A;  4WU2 A;  2VEX A;  4HRF A;  4DGP A;  2CMB A;  5KA8 A;  2B3O A;  1G4U S;  2F70 A;  4NX8 A;  1WCH A;  2B07 A;  1RPM A;  2H02 A;  5GTJ A;  2PT0 A;  4GFU A;  2A8B A;  2I6J A;  1JLN A;  3QCE A;  2I3R A;  3CM3 A;  2I3U A;  1NO6 A;  1R6H A;  1PTT A;  3I80 A;  1U26 A;  4HJP A;  2Q47 A;  3V0H A;  2PBN A;  4D3R A;  2I6M A;  4DGX A;  2B4O A;  2HCM A;  1GFY A; 
#chains in the Genus database with same CATH topology
 2BIJ A;  3ZM3 A;  1YTW A;  3QCZ A;  4GRZ A;  1Q6P A;  1C84 A;  3N0A A;  3EMU A;  1PXH A;  4I8N A;  2BZL A;  4YAA A;  4BJO A;  2GCA A;  4C13 A;  4CVK A;  3S3H A;  1C88 A;  4WU3 A;  2CNE A;  2ESB A;  3LJ8 A;  5MMZ B;  1XXP A;  4J51 A;  3S4O A;  5K24 A;  2HNP A;  4QDI A;  1YTS A;  1YWF A;  1VHR A;  2QBS A;  1GG4 A;  1Q6M A;  3ZV2 A;  4QAH A;  1OHC A;  4RHG A;  3ZMP A;  3BRH A;  1NWE A;  1GQQ A;  1Q6J A;  4KYQ A;  1E8C A;  5J8R A;  1V3A A;  3QKP A;  2OZ5 A;  4D3P A;  3ZM1 A;  2A3K A;  1J6U A;  4NND A;  4QUN A;  2CFV A;  4OHL A;  4NYH A;  4WTY A;  4Y2E A;  1O5Z A;  2H4V A;  1KAV A;  3OMH A;  2QBR A;  3D9C A;  2CM8 A;  2F6Y A;  4R30 A;  1XRI A;  2SHP A;  1YGR A;  3EB1 A;  4OHI A;  1QZ0 A;  2PA5 A;  2F00 A;  3ZM0 A;  2BV5 A;  2QBQ A;  1ZCL A;  3S3K A;  3CWE A;  2B4P A;  2QDM A;  1U24 A;  1JF7 A;  1UAG A;  2VEU A;  3QCC A;  4S0G A;  5I6V A;  2FJM A;  2AHS A;  2CM2 A;  5K23 A;  4YR8 B;  2AM2 A;  1LYV A;  4TVV A;  2HNQ A;  1BZC A;  1W7K A;  1NL9 A;  3QCD A;  2Y96 A;  4RI4 A;  3A5K A;  3RO1 A;  1FGS A;  2QEP A;  2WTZ A;  3NRS A;  4ZRT A;  3U96 A;  3HN7 A;  4GWF A;  1MKP A;  2F46 A;  5HDE A;  4RDD A;  4ZI4 A;  2F71 A;  2NZ6 A;  4QBW A;  4R0S A;  1Q6S A;  4GS0 A;  5A5F A;  2WJP A;  4QBE A;  4CVM A;  1FQ1 A;  5A5E A;  1T49 A;  3O4U A;  1WAX A;  1OES A;  2F6T A;  4PYH A;  3ZM6 A;  2CNF A;  5EHP A;  2ZMM A;  2FJN A;  2YDU A;  4MBB A;  1U25 A;  1LQF A;  3H2X A;  1OEO X;  1G1F A;  4H34 A;  3D1Q A;  3S4E A;  2Y67 A;  3D44 A;  2NTA A;  3ZMQ A;  2I1Y A;  2B49 A;  2J16 A;  2NV5 A;  2HC2 A;  1L8K A;  5KAC A;  2MBC A;  1PTV A;  1Q6N A;  2I6O A;  4QUM A;  5AWX A;  1BZH A;  2CNI A;  4CVL A;  3F41 A;  2B4S A;  2CMC A;  2UAG A;  3D1O A;  3MVN A;  3UAG A;  1PYN A;  3RGQ A;  1OET A;  2AM1 A;  3MOZ A;  4BUC A;  4GE5 A;  2BGD A;  3QCL A;  2C7S A;  2GP0 A;  2FH7 A;  4D3Q A;  2PSZ A;  2I4E A;  4GE6 A;  3RZ2 A;  1J4X A;  3PS5 A;  1YZ4 A;  2HC1 A;  2Y66 A;  2I4H A;  3OLR A;  2F6Z A;  3QCH A;  4HV4 A;  3PYZ A;  2H04 A;  3ZM5 A;  3V0J A;  3O4T A;  2R0B A;  3F9A A;  2F6W A;  1G7F A;  4ICZ A;  2G6Z A;  1G1H A;  1XXV A;  3ZL8 A;  3BLT A;  3F99 A;  1YGU A;  2XPC A;  3EU0 A;  1ONY A;  1JBV A;  5M43 A;  1T48 A;  2X5O A;  2NT7 A;  1C85 A;  4JNB A;  3AWF A;  1PA1 A;  1W78 A;  3B7O A;  1X24 A;  2CNG A;  2RF6 A;  2IMG A;  4R0T A;  3S3E A;  3F9B A;  1XBO A;  3QCM A;  3BM8 A;  5KAD A;  3MMJ A;  2CJZ A;  3S3F A;  2WGP A;  2OC3 A;  3D42 A;  1ZC0 A;  3V0F A;  2Q05 A;  1OEV A;  4IKC A;  3SME A;  1E0D A;  5K9W A;  1ONZ A;  2JFG A;  4PVG A;  2P4D A;  2QDP A;  2F6V A;  4JMJ A;  5IBS A;  1PH0 A;  1EEN A;  4OHD A;  4NWF A;  3GXH A;  1OHE A;  3MOW A;  1FPR A;  5KA4 A;  2ZN7 A;  3NME A;  3BLU A;  5K9V A;  2I6I A;  1G4W R;  2CNH A;  1G7G A;  4GRY A;  5KA3 A;  3I7Z A;  2CMA A;  4RH5 A;  1OEM X;  4JBC A;  1NWL A;  2GC5 A;  2PI7 A;  5IBM A;  2VOS A;  1G1G A;  3LK7 A;  2VOR A;  4OHE A;  1P15 A;  1A5Y A;  2H4G A;  1SUG A;  1EEO A;  3QCJ A;  1QXK A;  1EEH A;  2AZR A;  3QCF A;  3SR9 A;  2I5X A;  2VEV A;  1JBW A;  3EZZ A;  1PTU A;  3RGO A;  5KA1 A;  2VEW A;  3QCI A;  2Y68 A;  1T4J A;  2HVL A;  2QCT A;  3AWE A;  5EHR A;  2J17 A;  5KAB A;  2QBP A;  4ZIY A;  2UUP A;  4ZN5 A;  1YN9 A;  4RH9 A;  1PA9 A;  2E0T A;  2VTE A;  3QCB A;  2Y1O A;  1YFO A;  4BUB A;  1C83 A;  5KA2 A;  2QDC A;  5KA7 A;  4QF5 A;  2Y2F A;  2NT2 A;  3ZM2 A;  4QAP A;  3QCN A;  1M3G A;  3V0G A;  1C86 A;  2HY3 A;  2BGE A;  1NNY A;  2M3V A;  2VTD A;  3V0I A;  4KI9 A;  2PQ5 A;  3QCG A;  2I6P A;  1BZJ A;  1P31 A;  5BX1 A;  4BPC A;  2J16 B;  1XM2 A;  4NWG A;  5BUG A;  4RKK A;  2G59 A;  4JMK A;  3F81 A;  1L8G A;  2B4U A;  2QCJ A;  1I9S A;  1OEU A;  2OOQ A;  3M4U A;  1ZCK A;  2GCB A;  3V0E A;  3GXG A;  4GFV A;  1PTY A;  2C46 A;  3O3L A;  3QKQ A;  2CM3 A;  3O5X A;  1NZ7 A;  3AWG A;  3D1H A;  3I36 A;  2NLK A;  2GC6 A;  2UUO A;  1D5R A;  2P6X A;  4RI5 A;  5BZX A;  3A5J A;  2HB1 A;  2HXP A;  2I42 A;  2VEY A;  5BZZ A;  1C87 A;  2DXP A;  2F6F A;  3O4S A;  2XJA A;  1AAX A;  2CM7 A;  1YTN A;  2JJD A;  4H1O A;  2OUD A;  2GJT A;  1Q1M A;  4Z6B A;  4B04 A;  4AZ1 A;  4WOH A;  4GE2 A;  2H03 A;  2I75 A;  3V0D A;  5KAA A;  1GWZ A;  1LAR A;  1ZZW A;  5KA9 A;  1GQY A;  4HJQ A;  1FPZ A;  1RXD A;  5K25 A;  5LXQ B;  2GWO A;  1ECV A;  1YPT A;  3N2A A;  1WRM A;  1KAK A;  4OHH A;  3QCK A;  2H4K A;  2I4G A;  4Y14 A;  5KA0 A;  2JFH A;  1I57 A;  1I9T A;  1OHD A;  1Q6T A;  3EAX A;  5K22 A;  4ERC A;  4KYR A;  4C12 A;  4WU2 A;  2VEX A;  4HRF A;  4DGP A;  2CMB A;  5KA8 A;  1P3D A;  2B3O A;  1G4U S;  2F70 A;  4NX8 A;  1WCH A;  2B07 A;  1RPM A;  2H02 A;  5GTJ A;  2PT0 A;  4GFU A;  2A8B A;  2I6J A;  4UAG A;  1JLN A;  2JFF A;  3QCE A;  2I3R A;  3CM3 A;  2I3U A;  1NO6 A;  1R6H A;  1PTT A;  3I80 A;  1U26 A;  4HJP A;  2Q47 A;  3V0H A;  2PBN A;  4D3R A;  2I6M A;  4DGX A;  2B4O A;  2HCM A;  1GFY A; 
#chains in the Genus database with same CATH homology
 2BIJ A;  3ZM3 A;  1YTW A;  4GRZ A;  1Q6P A;  1C84 A;  3N0A A;  3EMU A;  1PXH A;  4I8N A;  2BZL A;  4YAA A;  4BJO A;  3S3H A;  1C88 A;  4WU3 A;  2CNE A;  2ESB A;  3LJ8 A;  5MMZ B;  1XXP A;  4J51 A;  3S4O A;  5K24 A;  2HNP A;  1YTS A;  1YWF A;  1VHR A;  2QBS A;  1Q6M A;  3ZV2 A;  4QAH A;  1OHC A;  4RHG A;  3ZMP A;  3BRH A;  1NWE A;  1Q6J A;  4KYQ A;  5J8R A;  1V3A A;  3QKP A;  2OZ5 A;  4D3P A;  3ZM1 A;  2A3K A;  4NND A;  4QUN A;  2CFV A;  4OHL A;  4NYH A;  4WTY A;  4Y2E A;  2H4V A;  1KAV A;  3OMH A;  2QBR A;  3D9C A;  2CM8 A;  2F6Y A;  4R30 A;  1XRI A;  2SHP A;  1YGR A;  3EB1 A;  4OHI A;  1QZ0 A;  2PA5 A;  3ZM0 A;  2BV5 A;  2QBQ A;  1ZCL A;  3S3K A;  3CWE A;  2B4P A;  2QDM A;  1U24 A;  1JF7 A;  2VEU A;  3QCC A;  4S0G A;  5I6V A;  2FJM A;  2AHS A;  2CM2 A;  5K23 A;  4YR8 B;  1LYV A;  4TVV A;  2HNQ A;  1BZC A;  1NL9 A;  3QCD A;  2Y96 A;  4RI4 A;  3A5K A;  3RO1 A;  2QEP A;  4ZRT A;  3U96 A;  4GWF A;  1MKP A;  2F46 A;  5HDE A;  4RDD A;  4ZI4 A;  2F71 A;  2NZ6 A;  4QBW A;  4R0S A;  1Q6S A;  4GS0 A;  4QBE A;  1FQ1 A;  1T49 A;  3O4U A;  1WAX A;  1OES A;  2F6T A;  4PYH A;  2CNF A;  5EHP A;  2ZMM A;  2FJN A;  2YDU A;  4MBB A;  1U25 A;  1LQF A;  3H2X A;  1OEO X;  1G1F A;  4H34 A;  3D1Q A;  3S4E A;  3D44 A;  2NTA A;  3ZMQ A;  2I1Y A;  2B49 A;  2J16 A;  2NV5 A;  2HC2 A;  1L8K A;  5KAC A;  2MBC A;  1PTV A;  1Q6N A;  2I6O A;  4QUM A;  5AWX A;  1BZH A;  2CNI A;  3F41 A;  2B4S A;  2CMC A;  3D1O A;  1PYN A;  3RGQ A;  1OET A;  3MOZ A;  4GE5 A;  2BGD A;  3QCL A;  2C7S A;  2GP0 A;  2FH7 A;  4D3Q A;  2PSZ A;  2I4E A;  4GE6 A;  3RZ2 A;  1J4X A;  3PS5 A;  1YZ4 A;  2HC1 A;  2I4H A;  3OLR A;  2F6Z A;  3QCH A;  2H04 A;  3V0J A;  3O4T A;  2R0B A;  3F9A A;  2F6W A;  1G7F A;  4ICZ A;  2G6Z A;  1G1H A;  1XXV A;  3BLT A;  3F99 A;  1YGU A;  3EU0 A;  1ONY A;  5M43 A;  1T48 A;  2NT7 A;  1C85 A;  4JNB A;  3AWF A;  1PA1 A;  3B7O A;  1X24 A;  2CNG A;  2RF6 A;  2IMG A;  4R0T A;  3S3E A;  3F9B A;  1XBO A;  3QCM A;  3BM8 A;  5KAD A;  3MMJ A;  2CJZ A;  3S3F A;  2WGP A;  2OC3 A;  3D42 A;  1ZC0 A;  3V0F A;  2Q05 A;  1OEV A;  4IKC A;  3SME A;  5K9W A;  1ONZ A;  4PVG A;  2P4D A;  2QDP A;  2F6V A;  4JMJ A;  5IBS A;  1PH0 A;  1EEN A;  4OHD A;  4NWF A;  3GXH A;  1OHE A;  3MOW A;  1FPR A;  5KA4 A;  2ZN7 A;  3NME A;  3BLU A;  5K9V A;  2I6I A;  1G4W R;  2CNH A;  1G7G A;  4GRY A;  5KA3 A;  3I7Z A;  2CMA A;  4RH5 A;  1OEM X;  4JBC A;  1NWL A;  2PI7 A;  5IBM A;  1G1G A;  4OHE A;  1P15 A;  1A5Y A;  2H4G A;  1SUG A;  1EEO A;  3QCJ A;  1QXK A;  2AZR A;  3QCF A;  3SR9 A;  2I5X A;  2VEV A;  3EZZ A;  1PTU A;  3RGO A;  5KA1 A;  2VEW A;  3QCI A;  1T4J A;  2HVL A;  2QCT A;  3AWE A;  5EHR A;  2J17 A;  5KAB A;  2QBP A;  4ZN5 A;  1YN9 A;  4RH9 A;  1PA9 A;  2E0T A;  3QCB A;  1YFO A;  1C83 A;  5KA2 A;  2QDC A;  5KA7 A;  2Y2F A;  2NT2 A;  3ZM2 A;  4QAP A;  3QCN A;  1M3G A;  3V0G A;  1C86 A;  2HY3 A;  2BGE A;  1NNY A;  2M3V A;  3V0I A;  4KI9 A;  2PQ5 A;  3QCG A;  2I6P A;  1BZJ A;  5BX1 A;  4BPC A;  2J16 B;  1XM2 A;  4NWG A;  5BUG A;  4RKK A;  2G59 A;  4JMK A;  3F81 A;  1L8G A;  2B4U A;  2QCJ A;  1I9S A;  1OEU A;  2OOQ A;  3M4U A;  1ZCK A;  3V0E A;  3GXG A;  4GFV A;  1PTY A;  2C46 A;  3O3L A;  3QKQ A;  2CM3 A;  3O5X A;  1NZ7 A;  3AWG A;  3D1H A;  3I36 A;  2NLK A;  1D5R A;  2P6X A;  4RI5 A;  5BZX A;  3A5J A;  2HB1 A;  2HXP A;  2I42 A;  2VEY A;  5BZZ A;  1C87 A;  2DXP A;  2F6F A;  3O4S A;  1AAX A;  2CM7 A;  1YTN A;  2JJD A;  4H1O A;  2OUD A;  2GJT A;  1Q1M A;  4Z6B A;  4B04 A;  4AZ1 A;  4WOH A;  4GE2 A;  2H03 A;  2I75 A;  3V0D A;  5KAA A;  1GWZ A;  1LAR A;  1ZZW A;  5KA9 A;  4HJQ A;  1FPZ A;  1RXD A;  5K25 A;  5LXQ B;  2GWO A;  1ECV A;  1YPT A;  1WRM A;  1KAK A;  4OHH A;  3QCK A;  2H4K A;  2I4G A;  4Y14 A;  5KA0 A;  1I57 A;  1I9T A;  1OHD A;  1Q6T A;  3EAX A;  5K22 A;  4ERC A;  4KYR A;  4WU2 A;  2VEX A;  4HRF A;  4DGP A;  2CMB A;  5KA8 A;  2B3O A;  1G4U S;  2F70 A;  4NX8 A;  1WCH A;  2B07 A;  1RPM A;  2H02 A;  5GTJ A;  2PT0 A;  4GFU A;  2A8B A;  2I6J A;  1JLN A;  3QCE A;  2I3R A;  3CM3 A;  2I3U A;  1NO6 A;  1R6H A;  1PTT A;  3I80 A;  1U26 A;  4HJP A;  2Q47 A;  3V0H A;  2PBN A;  4D3R A;  2I6M A;  4DGX A;  2B4O A;  2HCM A;  1GFY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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