4QBWA

The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
299
structure length
299
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 109
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4qbwA00
3U96A 2I3UA 1WRMA 1PTVA 1XXPA 1YTWA 3ZMPA 2I6JA 1Q6SA 4KYQA 4S0GA 5K23A 4NX8A 2I5XA 5GTJA 2F6WA 2B4OA 3V0JA 2C7SA 4WTYA 5KA7A 2VEWA 3S3FA 1OHDA 2PA5A 4PYHA 1C83A 4WU2A 4NYHA 2G6ZA 4QBEA 1P15A 1I57A 2HNPA 1JLNA 1OEUA 1WCHA 3QCBA 3F9BA 4ZN5A 1NO6A 1NNYA 4ZI4A 2PT0A 1G7FA 3AWGA 3QCKA 2C46A 5K22A 1Q6MA 3GXGA 1OESA 4NWGA 1RXDA 2QBSA 3EMUA 2H4KA 2DXPA 2F46A 2I75A 1JF7A 1XXVA 2CM7A 3ZM0A 3D44A 3A5KA 3QCEA 1YWFA 3AWEA 3V0DA 1PXHA 3QCDA 2BGDA 2VEYA 1G4US 1G1FA 1U26A 1MKPA 1G1GA 2HB1A 2OC3A 1EEOA 3RZ2A 3S3EA 1Q1MA 4YR8B 3EB1A 3SMEA 4B04A 1G7GA 2RF6A 3QCMA 3QCCA 1LQFA 1Q6TA 4D3QA 3F41A 2CM3A 1YPTA 2J17A 4RHGA 4GFVA 5KAAA 3RGQA 1FPZA 1C85A 1L8GA 3O4UA 2QDCA 2QCTA 4NWFA 2HCMA 4OHEA 4GRZA 1R6HA 4GRYA 2GWOA 2QBPA 2CNEA 2CNIA 2HC1A 1QZ0A 2CMBA 2I4EA 5KA3A 4HJPA 1T49A 2ZMMA 4OHLA 4Y2EA 3ZV2A 5BX1A 2QBQA 2B4SA 4RKKA 3EU0A 2PBNA 1Q6NA 4WOHA 2GJTA 1NZ7A 1I9SA 2A8BA 4R0SA 3O4SA 2I3RA 1LARA 4H1OA 2OUDA 2FH7A 1C86A 1U25A 2ZN7A 3OLRA 1T4JA 1YZ4A 2BGEA 5KACA 3N0AA 1PA1A 4GFUA 1ZCLA 1ONYA 3D42A 5M43A 2Y96A 1AAXA 1WAXA 2GP0A 1BZHA 1ZC0A 4AZ1A 1KAKA 4I8NA 2J16A 2QBRA 2F6ZA 5KABA 4RH5A 2Y2FA 3EZZA 1GWZA 4KYRA 4TVVA 3QCGA 3D1QA 3I36A 3SR9A 1XRIA 5BZXA 3V0GA 4GS0A 1D5RA 4ICZA 1NWLA 2B4UA 1T48A 1X24A 3S4OA 2I6PA 3EAXA 1BZJA 2I6IA 1PTTA 4GE6A 2R0BA 2AHSA 1ZCKA 3QCJA 5EHPA 1PYNA 2BZLA 2NTAA 3F9AA 5K9VA 5KA1A 4D3PA 1KAVA 2FJMA 2Q05A 1QXKA 2I1YA 2VEXA 3V0EA 2WGPA 4GE2A 1FPRA 5K25A 5K24A 2J16B 3D9CA 2YDUA 3ZM3A 4YAAA 4ZRTA 4PVGA 4BJOA 2H03A 2I6OA 3LJ8A 2H4VA 2PI7A 2P4DA 3AWFA 4RDDA 4IKCA 1V3AA 4QUMA 2F6VA 4QBWA 3GXHA 3M4UA 1NL9A 2IMGA 3B7OA 4GE5A 2SHPA 2ESBA 4JNBA 5KA4A 2I42A 1YN9A 2QEPA 1ECVA 3ZM1A 1OHCA 3OMHA 4BPCA 2CNFA 4Y14A 1GFYA 5I6VA 1J4XA 3F81A 1Q6JA 1M3GA 1LYVA 4R0TA 3BLUA 1C88A 5J8RA 3O3LA 4NNDA 2M3VA 5IBSA 2AZRA 2G59A 5KA2A 4JMKA 5IBMA 5AWXA 1OEMX 3V0IA 3BRHA 1A5YA 4RH9A 2JJDA 4GWFA 3ZM2A 2HY3A 2PSZA 4JMJA 2H04A 2NV5A 1G1HA 2B3OA 1I9TA 3QCNA 2F6FA 1OEOX 1XM2A 2OZ5A 2QCJA 4MBBA 2MBCA 1EENA 4H34A 1NWEA 2B07A 1C84A 3MMJA 2I4GA 1OETA 2P6XA 3I80A 3CM3A 2VEVA 3MOZA 3S3KA 1RPMA 2B4PA 3H2XA 1FQ1A 2F70A 1PH0A 2NLKA 2F71A 2A3KA 3I7ZA 2I4HA 2VEUA 2QDMA 3QCHA 4RI5A 2HVLA 3QKQA 3F99A 3S4EA 4D3RA 1PA9A 2F6YA 5KA8A 3ZMQA 3V0FA 1YFOA 1OHEA 2FJNA 1Q6PA 2CFVA 2H02A 2NZ6A 4Z6BA 5HDEA 4OHIA 2QDPA 3QCFA 1SUGA 3O5XA 5BZZA 3QCIA 2F6TA 5BUGA 1YGUA 3QKPA 2CMAA 1U24A 1ONZA 3O4TA 4QAHA 2CM8A 1ZZWA 2CJZA 4R30A 4HJQA 4HRFA 4RI4A 2B49A 2HXPA 2Q47A 4OHHA 4ERCA 1G4WR 1YGRA 2BV5A 5LXQB 3BLTA 3PS5A 3RO1A 3RGOA 3D1OA 2I6MA 4KI9A 4OHDA 2OOQA 3A5JA 5KA0A 2CMCA 1XBOA 4WU3A 1VHRA 2CNHA 2HNQA 1YTNA 4QUNA 3V0HA 3CWEA 2NT2A 1BZCA 3D1HA 5EHRA 3MOWA 2CM2A 3NMEA 5MMZB 1L8KA 1C87A 4QAPA 2BIJA 2H4GA 1OEVA 2HC2A 4DGPA 2E0TA 3S3HA 2NT7A 1YTSA 4J51A 5KADA 3BM8A 1PTUA 4DGXA 5KA9A 4JBCA 2PQ5A 2CNGA 5K9WA 3QCLA 1PTYA
chains in the Genus database with same CATH superfamily
4QDIA 5A5FA 2X5OA 3U96A 2I3UA 1WRMA 1PTVA 1XXPA 1YTWA 3ZMPA 2I6JA 2AM1A 1Q6SA 2GC5A 3ZM5A 4KYQA 4S0GA 4QF5A 5K23A 4NX8A 2I5XA 5GTJA 2F6WA 2B4OA 3V0JA 2C7SA 4WTYA 5KA7A 2VEWA 3S3FA 1GQYA 1OHDA 2PA5A 4PYHA 4HV4A 1C83A 4WU2A 3LK7A 4NYHA 2G6ZA 4QBEA 1P15A 1I57A 2HNPA 1JLNA 2AM2A 1OEUA 1WCHA 3QCBA 3F9BA 4ZN5A 1NO6A 1NNYA 4ZI4A 1UAGA 2PT0A 1G7FA 3AWGA 3QCKA 2C46A 4ZIYA 5K22A 1Q6MA 3GXGA 1OESA 4NWGA 1RXDA 2QBSA 3EMUA 2H4KA 2DXPA 2F46A 2I75A 1JF7A 1XXVA 2CM7A 3ZM0A 4C12A 3D44A 3A5KA 3QCEA 1J6UA 1YWFA 3AWEA 3V0DA 1W7KA 1PXHA 3QCDA 2BGDA 2VEYA 1G4US 1G1FA 1U26A 1MKPA 1G1GA 2HB1A 2OC3A 1EEOA 3RZ2A 3S3EA 1Q1MA 4YR8B 3EB1A 3SMEA 3ZM6A 4B04A 1G7GA 2RF6A 3QCMA 3QCCA 1LQFA 1Q6TA 4D3QA 2GCAA 2Y66A 3F41A 2CM3A 1YPTA 2J17A 4RHGA 4GFVA 5KAAA 3RGQA 1FPZA 1C85A 1L8GA 3O4UA 2QDCA 2QCTA 4NWFA 2HCMA 4OHEA 4GRZA 1R6HA 4GRYA 2GWOA 3UAGA 2GC6A 2QBPA 2CNEA 2CNIA 2HC1A 1QZ0A 2CMBA 2I4EA 5KA3A 4HJPA 1T49A 2ZMMA 4OHLA 4Y2EA 3ZV2A 5BX1A 2QBQA 2B4SA 4RKKA 2GCBA 3EU0A 2PBNA 1Q6NA 4WOHA 2GJTA 1JBVA 1NZ7A 1I9SA 2A8BA 4R0SA 2JFGA 3O4SA 2I3RA 1LARA 4H1OA 2OUDA 2FH7A 1C86A 1U25A 2ZN7A 2VOSA 3OLRA 1T4JA 1YZ4A 3NRSA 2BGEA 5KACA 3N0AA 1PA1A 4GFUA 1ZCLA 1ONYA 3D42A 5M43A 2F00A 2Y96A 1P3DA 1AAXA 4UAGA 1WAXA 2GP0A 1BZHA 4C13A 1ZC0A 4AZ1A 2Y68A 1KAKA 4I8NA 2J16A 2QBRA 2F6ZA 5KABA 4RH5A 2Y2FA 3EZZA 1GWZA 4KYRA 4TVVA 3QCGA 3D1QA 3I36A 2JFHA 1XRIA 3SR9A 5BZXA 3V0GA 4GS0A 1D5RA 4ICZA 1O5ZA 1NWLA 2B4UA 4BUCA 4CVKA 1T48A 1X24A 3S4OA 2I6PA 3EAXA 1BZJA 2I6IA 1PTTA 4GE6A 1W78A 2R0BA 2AHSA 4CVMA 1ZCKA 3QCJA 5EHPA 1PYNA 2BZLA 2NTAA 3F9AA 5K9VA 5KA1A 4D3PA 1KAVA 2FJMA 2Q05A 1QXKA 2I1YA 2VEXA 3V0EA 2WGPA 4GE2A 1FPRA 5K25A 5K24A 2J16B 3D9CA 2YDUA 3ZM3A 4YAAA 4ZRTA 4PVGA 4BJOA 2H03A 2UUPA 2I6OA 3LJ8A 2XJAA 2H4VA 2PI7A 2P4DA 3AWFA 4RDDA 4IKCA 1V3AA 1E8CA 4QUMA 2F6VA 4QBWA 2VTDA 3GXHA 3M4UA 1NL9A 2IMGA 3B7OA 4GE5A 2SHPA 2ESBA 4JNBA 5KA4A 2I42A 1YN9A 2QEPA 1ECVA 3ZM1A 1OHCA 1JBWA 3OMHA 4BPCA 2CNFA 4Y14A 1GFYA 5I6VA 1J4XA 3F81A 1GQQA 1Q6JA 1FGSA 1M3GA 1LYVA 4R0TA 3BLUA 1C88A 2XPCA 5J8RA 3O3LA 4NNDA 2VTEA 2M3VA 5IBSA 2AZRA 2G59A 5KA2A 4JMKA 5IBMA 5AWXA 1OEMX 3V0IA 3BRHA 1A5YA 4RH9A 2JJDA 4GWFA 3ZM2A 2HY3A 2PSZA 4JMJA 3PYZA 2H04A 2NV5A 2JFFA 1G1HA 4BUBA 2B3OA 1I9TA 3QCNA 2F6FA 1OEOX 1XM2A 2OZ5A 2Y1OA 2QCJA 4MBBA 2MBCA 1EENA 4H34A 1NWEA 2B07A 1C84A 3MMJA 1GG4A 2I4GA 1OETA 2WTZA 2P6XA 3CM3A 3I80A 2VEVA 3HN7A 3MOZA 3S3KA 1RPMA 2B4PA 3H2XA 1FQ1A 2F70A 3QCZA 1PH0A 2NLKA 2F71A 2A3KA 3I7ZA 2I4HA 2VEUA 2QDMA 3QCHA 4RI5A 2HVLA 3QKQA 3F99A 3S4EA 4D3RA 1PA9A 2F6YA 5KA8A 3ZMQA 3V0FA 1YFOA 1OHEA 2FJNA 1Q6PA 2CFVA 2H02A 2NZ6A 4Z6BA 5HDEA 4OHIA 2QDPA 3QCFA 1SUGA 3O5XA 5BZZA 3QCIA 2F6TA 4CVLA 5BUGA 1YGUA 3QKPA 2CMAA 1U24A 1ONZA 3MVNA 3O4TA 4QAHA 2CM8A 1ZZWA 2CJZA 2UUOA 4R30A 4HJQA 4HRFA 4RI4A 2B49A 2HXPA 2Q47A 4OHHA 4ERCA 1G4WR 2Y67A 1YGRA 2BV5A 1EEHA 5LXQB 3BLTA 1E0DA 3PS5A 3RO1A 3RGOA 3D1OA 2I6MA 4KI9A 4OHDA 2OOQA 3A5JA 5KA0A 2CMCA 1P31A 1XBOA 4WU3A 1VHRA 2CNHA 2HNQA 1YTNA 3ZL8A 2UAGA 4QUNA 3V0HA 3CWEA 2NT2A 1BZCA 3D1HA 5EHRA 3MOWA 2CM2A 2VORA 3NMEA 5MMZB 1L8KA 1C87A 4QAPA 2WJPA 2BIJA 2H4GA 1OEVA 2HC2A 4DGPA 2E0TA 3S3HA 2NT7A 1YTSA 4J51A 5A5EA 5KADA 3BM8A 3N2AA 1PTUA 4DGXA 5KA9A 4JBCA 2PQ5A 2CNGA 5K9WA 3QCLA 1PTYA
chains in the Genus database with same CATH topology
3U96A 2I3UA 1WRMA 1PTVA 1XXPA 1YTWA 3ZMPA 2I6JA 1Q6SA 4KYQA 4S0GA 5K23A 4NX8A 2I5XA 5GTJA 2F6WA 2B4OA 3V0JA 2C7SA 4WTYA 5KA7A 2VEWA 3S3FA 1OHDA 2PA5A 4PYHA 1C83A 4WU2A 4NYHA 2G6ZA 4QBEA 1P15A 1I57A 2HNPA 1JLNA 1OEUA 1WCHA 3QCBA 3F9BA 4ZN5A 1NO6A 1NNYA 4ZI4A 2PT0A 1G7FA 3AWGA 3QCKA 2C46A 5K22A 1Q6MA 3GXGA 1OESA 4NWGA 1RXDA 2QBSA 3EMUA 2H4KA 2DXPA 2F46A 2I75A 1JF7A 1XXVA 2CM7A 3ZM0A 3D44A 3A5KA 3QCEA 1YWFA 3AWEA 3V0DA 1PXHA 3QCDA 2BGDA 2VEYA 1G4US 1G1FA 1U26A 1MKPA 1G1GA 2HB1A 2OC3A 1EEOA 3RZ2A 3S3EA 1Q1MA 4YR8B 3EB1A 3SMEA 4B04A 1G7GA 2RF6A 3QCMA 3QCCA 1LQFA 1Q6TA 4D3QA 3F41A 2CM3A 1YPTA 2J17A 4RHGA 4GFVA 5KAAA 3RGQA 1FPZA 1C85A 1L8GA 3O4UA 2QDCA 2QCTA 4NWFA 2HCMA 4OHEA 4GRZA 1R6HA 4GRYA 2GWOA 2QBPA 2CNEA 2CNIA 2HC1A 1QZ0A 2CMBA 2I4EA 5KA3A 4HJPA 1T49A 2ZMMA 4OHLA 4Y2EA 3ZV2A 5BX1A 2QBQA 2B4SA 4RKKA 3EU0A 2PBNA 1Q6NA 4WOHA 2GJTA 1NZ7A 1I9SA 2A8BA 4R0SA 3O4SA 2I3RA 1LARA 4H1OA 2OUDA 2FH7A 1C86A 1U25A 2ZN7A 3OLRA 1T4JA 1YZ4A 2BGEA 5KACA 3N0AA 1PA1A 4GFUA 1ZCLA 1ONYA 3D42A 5M43A 2Y96A 1AAXA 1WAXA 2GP0A 1BZHA 1ZC0A 4AZ1A 1KAKA 4I8NA 2J16A 2QBRA 2F6ZA 5KABA 4RH5A 2Y2FA 3EZZA 1GWZA 4KYRA 4TVVA 3QCGA 3D1QA 3I36A 3SR9A 1XRIA 5BZXA 3V0GA 4GS0A 1D5RA 4ICZA 1NWLA 2B4UA 1T48A 1X24A 3S4OA 2I6PA 3EAXA 1BZJA 2I6IA 1PTTA 4GE6A 2R0BA 2AHSA 1ZCKA 3QCJA 5EHPA 1PYNA 2BZLA 2NTAA 3F9AA 5K9VA 5KA1A 4D3PA 1KAVA 2FJMA 2Q05A 1QXKA 2I1YA 2VEXA 3V0EA 2WGPA 4GE2A 1FPRA 5K25A 5K24A 2J16B 3D9CA 2YDUA 3ZM3A 4YAAA 4ZRTA 4PVGA 4BJOA 2H03A 2I6OA 3LJ8A 2H4VA 2PI7A 2P4DA 3AWFA 4RDDA 4IKCA 1V3AA 4QUMA 2F6VA 4QBWA 3GXHA 3M4UA 1NL9A 2IMGA 3B7OA 4GE5A 2SHPA 2ESBA 4JNBA 5KA4A 2I42A 1YN9A 2QEPA 1ECVA 3ZM1A 1OHCA 3OMHA 4BPCA 2CNFA 4Y14A 1GFYA 5I6VA 1J4XA 3F81A 1Q6JA 1M3GA 1LYVA 4R0TA 3BLUA 1C88A 5J8RA 3O3LA 4NNDA 2M3VA 5IBSA 2AZRA 2G59A 5KA2A 4JMKA 5IBMA 5AWXA 1OEMX 3V0IA 3BRHA 1A5YA 4RH9A 2JJDA 4GWFA 3ZM2A 2HY3A 2PSZA 4JMJA 2H04A 2NV5A 1G1HA 2B3OA 1I9TA 3QCNA 2F6FA 1OEOX 1XM2A 2OZ5A 2QCJA 4MBBA 2MBCA 1EENA 4H34A 1NWEA 2B07A 1C84A 3MMJA 2I4GA 1OETA 2P6XA 3I80A 3CM3A 2VEVA 3MOZA 3S3KA 1RPMA 2B4PA 3H2XA 1FQ1A 2F70A 1PH0A 2NLKA 2F71A 2A3KA 3I7ZA 2I4HA 2VEUA 2QDMA 3QCHA 4RI5A 2HVLA 3QKQA 3F99A 3S4EA 4D3RA 1PA9A 2F6YA 5KA8A 3ZMQA 3V0FA 1YFOA 1OHEA 2FJNA 1Q6PA 2CFVA 2H02A 2NZ6A 4Z6BA 5HDEA 4OHIA 2QDPA 3QCFA 1SUGA 3O5XA 5BZZA 3QCIA 2F6TA 5BUGA 1YGUA 3QKPA 2CMAA 1U24A 1ONZA 3O4TA 4QAHA 2CM8A 1ZZWA 2CJZA 4R30A 4HJQA 4HRFA 4RI4A 2B49A 2HXPA 2Q47A 4OHHA 4ERCA 1G4WR 1YGRA 2BV5A 5LXQB 3BLTA 3PS5A 3RO1A 3RGOA 3D1OA 2I6MA 4KI9A 4OHDA 2OOQA 3A5JA 5KA0A 2CMCA 1XBOA 4WU3A 1VHRA 2CNHA 2HNQA 1YTNA 4QUNA 3V0HA 3CWEA 2NT2A 1BZCA 3D1HA 5EHRA 3MOWA 2CM2A 3NMEA 5MMZB 1L8KA 1C87A 4QAPA 2BIJA 2H4GA 1OEVA 2HC2A 4DGPA 2E0TA 3S3HA 2NT7A 1YTSA 4J51A 5KADA 3BM8A 1PTUA 4DGXA 5KA9A 4JBCA 2PQ5A 2CNGA 5K9WA 3QCLA 1PTYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U96 A;  2I3U A;  1WRM A;  1PTV A;  1XXP A;  1YTW A;  3ZMP A;  2I6J A;  1Q6S A;  4KYQ A;  4S0G A;  5K23 A;  4NX8 A;  2I5X A;  5GTJ A;  2F6W A;  2B4O A;  3V0J A;  2C7S A;  4WTY A;  5KA7 A;  2VEW A;  3S3F A;  1OHD A;  2PA5 A;  4PYH A;  1C83 A;  4WU2 A;  4NYH A;  2G6Z A;  4QBE A;  1P15 A;  1I57 A;  2HNP A;  1JLN A;  1OEU A;  1WCH A;  3QCB A;  3F9B A;  4ZN5 A;  1NO6 A;  1NNY A;  4ZI4 A;  2PT0 A;  1G7F A;  3AWG A;  3QCK A;  2C46 A;  5K22 A;  1Q6M A;  3GXG A;  1OES A;  4NWG A;  1RXD A;  2QBS A;  3EMU A;  2H4K A;  2DXP A;  2F46 A;  2I75 A;  1JF7 A;  1XXV A;  2CM7 A;  3ZM0 A;  3D44 A;  3A5K A;  3QCE A;  1YWF A;  3AWE A;  3V0D A;  1PXH A;  3QCD A;  2BGD A;  2VEY A;  1G4U S;  1G1F A;  1U26 A;  1MKP A;  1G1G A;  2HB1 A;  2OC3 A;  1EEO A;  3RZ2 A;  3S3E A;  1Q1M A;  4YR8 B;  3EB1 A;  3SME A;  4B04 A;  1G7G A;  2RF6 A;  3QCM A;  3QCC A;  1LQF A;  1Q6T A;  4D3Q A;  3F41 A;  2CM3 A;  1YPT A;  2J17 A;  4RHG A;  4GFV A;  5KAA A;  3RGQ A;  1FPZ A;  1C85 A;  1L8G A;  3O4U A;  2QDC A;  2QCT A;  4NWF A;  2HCM A;  4OHE A;  4GRZ A;  1R6H A;  4GRY A;  2GWO A;  2QBP A;  2CNE A;  2CNI A;  2HC1 A;  1QZ0 A;  2CMB A;  2I4E A;  5KA3 A;  4HJP A;  1T49 A;  2ZMM A;  4OHL A;  4Y2E A;  3ZV2 A;  5BX1 A;  2QBQ A;  2B4S A;  4RKK A;  3EU0 A;  2PBN A;  1Q6N A;  4WOH A;  2GJT A;  1NZ7 A;  1I9S A;  2A8B A;  4R0S A;  3O4S A;  2I3R A;  1LAR A;  4H1O A;  2OUD A;  2FH7 A;  1C86 A;  1U25 A;  2ZN7 A;  3OLR A;  1T4J A;  1YZ4 A;  2BGE A;  5KAC A;  3N0A A;  1PA1 A;  4GFU A;  1ZCL A;  1ONY A;  3D42 A;  5M43 A;  2Y96 A;  1AAX A;  1WAX A;  2GP0 A;  1BZH A;  1ZC0 A;  4AZ1 A;  1KAK A;  4I8N A;  2J16 A;  2QBR A;  2F6Z A;  5KAB A;  4RH5 A;  2Y2F A;  3EZZ A;  1GWZ A;  4KYR A;  4TVV A;  3QCG A;  3D1Q A;  3I36 A;  3SR9 A;  1XRI A;  5BZX A;  3V0G A;  4GS0 A;  1D5R A;  4ICZ A;  1NWL A;  2B4U A;  1T48 A;  1X24 A;  3S4O A;  2I6P A;  3EAX A;  1BZJ A;  2I6I A;  1PTT A;  4GE6 A;  2R0B A;  2AHS A;  1ZCK A;  3QCJ A;  5EHP A;  1PYN A;  2BZL A;  2NTA A;  3F9A A;  5K9V A;  5KA1 A;  4D3P A;  1KAV A;  2FJM A;  2Q05 A;  1QXK A;  2I1Y A;  2VEX A;  3V0E A;  2WGP A;  4GE2 A;  1FPR A;  5K25 A;  5K24 A;  2J16 B;  3D9C A;  2YDU A;  3ZM3 A;  4YAA A;  4ZRT A;  4PVG A;  4BJO A;  2H03 A;  2I6O A;  3LJ8 A;  2H4V A;  2PI7 A;  2P4D A;  3AWF A;  4RDD A;  4IKC A;  1V3A A;  4QUM A;  2F6V A;  4QBW A;  3GXH A;  3M4U A;  1NL9 A;  2IMG A;  3B7O A;  4GE5 A;  2SHP A;  2ESB A;  4JNB A;  5KA4 A;  2I42 A;  1YN9 A;  2QEP A;  1ECV A;  3ZM1 A;  1OHC A;  3OMH A;  4BPC A;  2CNF A;  4Y14 A;  1GFY A;  5I6V A;  1J4X A;  3F81 A;  1Q6J A;  1M3G A;  1LYV A;  4R0T A;  3BLU A;  1C88 A;  5J8R A;  3O3L A;  4NND A;  2M3V A;  5IBS A;  2AZR A;  2G59 A;  5KA2 A;  4JMK A;  5IBM A;  5AWX A;  1OEM X;  3V0I A;  3BRH A;  1A5Y A;  4RH9 A;  2JJD A;  4GWF A;  3ZM2 A;  2HY3 A;  2PSZ A;  4JMJ A;  2H04 A;  2NV5 A;  1G1H A;  2B3O A;  1I9T A;  3QCN A;  2F6F A;  1OEO X;  1XM2 A;  2OZ5 A;  2QCJ A;  4MBB A;  2MBC A;  1EEN A;  4H34 A;  1NWE A;  2B07 A;  1C84 A;  3MMJ A;  2I4G A;  1OET A;  2P6X A;  3I80 A;  3CM3 A;  2VEV A;  3MOZ A;  3S3K A;  1RPM A;  2B4P A;  3H2X A;  1FQ1 A;  2F70 A;  1PH0 A;  2NLK A;  2F71 A;  2A3K A;  3I7Z A;  2I4H A;  2VEU A;  2QDM A;  3QCH A;  4RI5 A;  2HVL A;  3QKQ A;  3F99 A;  3S4E A;  4D3R A;  1PA9 A;  2F6Y A;  5KA8 A;  3ZMQ A;  3V0F A;  1YFO A;  1OHE A;  2FJN A;  1Q6P A;  2CFV A;  2H02 A;  2NZ6 A;  4Z6B A;  5HDE A;  4OHI A;  2QDP A;  3QCF A;  1SUG A;  3O5X A;  5BZZ A;  3QCI A;  2F6T A;  5BUG A;  1YGU A;  3QKP A;  2CMA A;  1U24 A;  1ONZ A;  3O4T A;  4QAH A;  2CM8 A;  1ZZW A;  2CJZ A;  4R30 A;  4HJQ A;  4HRF A;  4RI4 A;  2B49 A;  2HXP A;  2Q47 A;  4OHH A;  4ERC A;  1G4W R;  1YGR A;  2BV5 A;  5LXQ B;  3BLT A;  3PS5 A;  3RO1 A;  3RGO A;  3D1O A;  2I6M A;  4KI9 A;  4OHD A;  2OOQ A;  3A5J A;  5KA0 A;  2CMC A;  1XBO A;  4WU3 A;  1VHR A;  2CNH A;  2HNQ A;  1YTN A;  4QUN A;  3V0H A;  3CWE A;  2NT2 A;  1BZC A;  3D1H A;  5EHR A;  3MOW A;  2CM2 A;  3NME A;  5MMZ B;  1L8K A;  1C87 A;  4QAP A;  2BIJ A;  2H4G A;  1OEV A;  2HC2 A;  4DGP A;  2E0T A;  3S3H A;  2NT7 A;  1YTS A;  4J51 A;  5KAD A;  3BM8 A;  1PTU A;  4DGX A;  5KA9 A;  4JBC A;  2PQ5 A;  2CNG A;  5K9W A;  3QCL A;  1PTY A; 
#chains in the Genus database with same CATH topology
 4QDI A;  5A5F A;  2X5O A;  3U96 A;  2I3U A;  1WRM A;  1PTV A;  1XXP A;  1YTW A;  3ZMP A;  2I6J A;  2AM1 A;  1Q6S A;  2GC5 A;  3ZM5 A;  4KYQ A;  4S0G A;  4QF5 A;  5K23 A;  4NX8 A;  2I5X A;  5GTJ A;  2F6W A;  2B4O A;  3V0J A;  2C7S A;  4WTY A;  5KA7 A;  2VEW A;  3S3F A;  1GQY A;  1OHD A;  2PA5 A;  4PYH A;  4HV4 A;  1C83 A;  4WU2 A;  3LK7 A;  4NYH A;  2G6Z A;  4QBE A;  1P15 A;  1I57 A;  2HNP A;  1JLN A;  2AM2 A;  1OEU A;  1WCH A;  3QCB A;  3F9B A;  4ZN5 A;  1NO6 A;  1NNY A;  4ZI4 A;  1UAG A;  2PT0 A;  1G7F A;  3AWG A;  3QCK A;  2C46 A;  4ZIY A;  5K22 A;  1Q6M A;  3GXG A;  1OES A;  4NWG A;  1RXD A;  2QBS A;  3EMU A;  2H4K A;  2DXP A;  2F46 A;  2I75 A;  1JF7 A;  1XXV A;  2CM7 A;  3ZM0 A;  4C12 A;  3D44 A;  3A5K A;  3QCE A;  1J6U A;  1YWF A;  3AWE A;  3V0D A;  1W7K A;  1PXH A;  3QCD A;  2BGD A;  2VEY A;  1G4U S;  1G1F A;  1U26 A;  1MKP A;  1G1G A;  2HB1 A;  2OC3 A;  1EEO A;  3RZ2 A;  3S3E A;  1Q1M A;  4YR8 B;  3EB1 A;  3SME A;  3ZM6 A;  4B04 A;  1G7G A;  2RF6 A;  3QCM A;  3QCC A;  1LQF A;  1Q6T A;  4D3Q A;  2GCA A;  2Y66 A;  3F41 A;  2CM3 A;  1YPT A;  2J17 A;  4RHG A;  4GFV A;  5KAA A;  3RGQ A;  1FPZ A;  1C85 A;  1L8G A;  3O4U A;  2QDC A;  2QCT A;  4NWF A;  2HCM A;  4OHE A;  4GRZ A;  1R6H A;  4GRY A;  2GWO A;  3UAG A;  2GC6 A;  2QBP A;  2CNE A;  2CNI A;  2HC1 A;  1QZ0 A;  2CMB A;  2I4E A;  5KA3 A;  4HJP A;  1T49 A;  2ZMM A;  4OHL A;  4Y2E A;  3ZV2 A;  5BX1 A;  2QBQ A;  2B4S A;  4RKK A;  2GCB A;  3EU0 A;  2PBN A;  1Q6N A;  4WOH A;  2GJT A;  1JBV A;  1NZ7 A;  1I9S A;  2A8B A;  4R0S A;  2JFG A;  3O4S A;  2I3R A;  1LAR A;  4H1O A;  2OUD A;  2FH7 A;  1C86 A;  1U25 A;  2ZN7 A;  2VOS A;  3OLR A;  1T4J A;  1YZ4 A;  3NRS A;  2BGE A;  5KAC A;  3N0A A;  1PA1 A;  4GFU A;  1ZCL A;  1ONY A;  3D42 A;  5M43 A;  2F00 A;  2Y96 A;  1P3D A;  1AAX A;  4UAG A;  1WAX A;  2GP0 A;  1BZH A;  4C13 A;  1ZC0 A;  4AZ1 A;  2Y68 A;  1KAK A;  4I8N A;  2J16 A;  2QBR A;  2F6Z A;  5KAB A;  4RH5 A;  2Y2F A;  3EZZ A;  1GWZ A;  4KYR A;  4TVV A;  3QCG A;  3D1Q A;  3I36 A;  2JFH A;  1XRI A;  3SR9 A;  5BZX A;  3V0G A;  4GS0 A;  1D5R A;  4ICZ A;  1O5Z A;  1NWL A;  2B4U A;  4BUC A;  4CVK A;  1T48 A;  1X24 A;  3S4O A;  2I6P A;  3EAX A;  1BZJ A;  2I6I A;  1PTT A;  4GE6 A;  1W78 A;  2R0B A;  2AHS A;  4CVM A;  1ZCK A;  3QCJ A;  5EHP A;  1PYN A;  2BZL A;  2NTA A;  3F9A A;  5K9V A;  5KA1 A;  4D3P A;  1KAV A;  2FJM A;  2Q05 A;  1QXK A;  2I1Y A;  2VEX A;  3V0E A;  2WGP A;  4GE2 A;  1FPR A;  5K25 A;  5K24 A;  2J16 B;  3D9C A;  2YDU A;  3ZM3 A;  4YAA A;  4ZRT A;  4PVG A;  4BJO A;  2H03 A;  2UUP A;  2I6O A;  3LJ8 A;  2XJA A;  2H4V A;  2PI7 A;  2P4D A;  3AWF A;  4RDD A;  4IKC A;  1V3A A;  1E8C A;  4QUM A;  2F6V A;  4QBW A;  2VTD A;  3GXH A;  3M4U A;  1NL9 A;  2IMG A;  3B7O A;  4GE5 A;  2SHP A;  2ESB A;  4JNB A;  5KA4 A;  2I42 A;  1YN9 A;  2QEP A;  1ECV A;  3ZM1 A;  1OHC A;  1JBW A;  3OMH A;  4BPC A;  2CNF A;  4Y14 A;  1GFY A;  5I6V A;  1J4X A;  3F81 A;  1GQQ A;  1Q6J A;  1FGS A;  1M3G A;  1LYV A;  4R0T A;  3BLU A;  1C88 A;  2XPC A;  5J8R A;  3O3L A;  4NND A;  2VTE A;  2M3V A;  5IBS A;  2AZR A;  2G59 A;  5KA2 A;  4JMK A;  5IBM A;  5AWX A;  1OEM X;  3V0I A;  3BRH A;  1A5Y A;  4RH9 A;  2JJD A;  4GWF A;  3ZM2 A;  2HY3 A;  2PSZ A;  4JMJ A;  3PYZ A;  2H04 A;  2NV5 A;  2JFF A;  1G1H A;  4BUB A;  2B3O A;  1I9T A;  3QCN A;  2F6F A;  1OEO X;  1XM2 A;  2OZ5 A;  2Y1O A;  2QCJ A;  4MBB A;  2MBC A;  1EEN A;  4H34 A;  1NWE A;  2B07 A;  1C84 A;  3MMJ A;  1GG4 A;  2I4G A;  1OET A;  2WTZ A;  2P6X A;  3CM3 A;  3I80 A;  2VEV A;  3HN7 A;  3MOZ A;  3S3K A;  1RPM A;  2B4P A;  3H2X A;  1FQ1 A;  2F70 A;  3QCZ A;  1PH0 A;  2NLK A;  2F71 A;  2A3K A;  3I7Z A;  2I4H A;  2VEU A;  2QDM A;  3QCH A;  4RI5 A;  2HVL A;  3QKQ A;  3F99 A;  3S4E A;  4D3R A;  1PA9 A;  2F6Y A;  5KA8 A;  3ZMQ A;  3V0F A;  1YFO A;  1OHE A;  2FJN A;  1Q6P A;  2CFV A;  2H02 A;  2NZ6 A;  4Z6B A;  5HDE A;  4OHI A;  2QDP A;  3QCF A;  1SUG A;  3O5X A;  5BZZ A;  3QCI A;  2F6T A;  4CVL A;  5BUG A;  1YGU A;  3QKP A;  2CMA A;  1U24 A;  1ONZ A;  3MVN A;  3O4T A;  4QAH A;  2CM8 A;  1ZZW A;  2CJZ A;  2UUO A;  4R30 A;  4HJQ A;  4HRF A;  4RI4 A;  2B49 A;  2HXP A;  2Q47 A;  4OHH A;  4ERC A;  1G4W R;  2Y67 A;  1YGR A;  2BV5 A;  1EEH A;  5LXQ B;  3BLT A;  1E0D A;  3PS5 A;  3RO1 A;  3RGO A;  3D1O A;  2I6M A;  4KI9 A;  4OHD A;  2OOQ A;  3A5J A;  5KA0 A;  2CMC A;  1P31 A;  1XBO A;  4WU3 A;  1VHR A;  2CNH A;  2HNQ A;  1YTN A;  3ZL8 A;  2UAG A;  4QUN A;  3V0H A;  3CWE A;  2NT2 A;  1BZC A;  3D1H A;  5EHR A;  3MOW A;  2CM2 A;  2VOR A;  3NME A;  5MMZ B;  1L8K A;  1C87 A;  4QAP A;  2WJP A;  2BIJ A;  2H4G A;  1OEV A;  2HC2 A;  4DGP A;  2E0T A;  3S3H A;  2NT7 A;  1YTS A;  4J51 A;  5A5E A;  5KAD A;  3BM8 A;  3N2A A;  1PTU A;  4DGX A;  5KA9 A;  4JBC A;  2PQ5 A;  2CNG A;  5K9W A;  3QCL A;  1PTY A; 
#chains in the Genus database with same CATH homology
 3U96 A;  2I3U A;  1WRM A;  1PTV A;  1XXP A;  1YTW A;  3ZMP A;  2I6J A;  1Q6S A;  4KYQ A;  4S0G A;  5K23 A;  4NX8 A;  2I5X A;  5GTJ A;  2F6W A;  2B4O A;  3V0J A;  2C7S A;  4WTY A;  5KA7 A;  2VEW A;  3S3F A;  1OHD A;  2PA5 A;  4PYH A;  1C83 A;  4WU2 A;  4NYH A;  2G6Z A;  4QBE A;  1P15 A;  1I57 A;  2HNP A;  1JLN A;  1OEU A;  1WCH A;  3QCB A;  3F9B A;  4ZN5 A;  1NO6 A;  1NNY A;  4ZI4 A;  2PT0 A;  1G7F A;  3AWG A;  3QCK A;  2C46 A;  5K22 A;  1Q6M A;  3GXG A;  1OES A;  4NWG A;  1RXD A;  2QBS A;  3EMU A;  2H4K A;  2DXP A;  2F46 A;  2I75 A;  1JF7 A;  1XXV A;  2CM7 A;  3ZM0 A;  3D44 A;  3A5K A;  3QCE A;  1YWF A;  3AWE A;  3V0D A;  1PXH A;  3QCD A;  2BGD A;  2VEY A;  1G4U S;  1G1F A;  1U26 A;  1MKP A;  1G1G A;  2HB1 A;  2OC3 A;  1EEO A;  3RZ2 A;  3S3E A;  1Q1M A;  4YR8 B;  3EB1 A;  3SME A;  4B04 A;  1G7G A;  2RF6 A;  3QCM A;  3QCC A;  1LQF A;  1Q6T A;  4D3Q A;  3F41 A;  2CM3 A;  1YPT A;  2J17 A;  4RHG A;  4GFV A;  5KAA A;  3RGQ A;  1FPZ A;  1C85 A;  1L8G A;  3O4U A;  2QDC A;  2QCT A;  4NWF A;  2HCM A;  4OHE A;  4GRZ A;  1R6H A;  4GRY A;  2GWO A;  2QBP A;  2CNE A;  2CNI A;  2HC1 A;  1QZ0 A;  2CMB A;  2I4E A;  5KA3 A;  4HJP A;  1T49 A;  2ZMM A;  4OHL A;  4Y2E A;  3ZV2 A;  5BX1 A;  2QBQ A;  2B4S A;  4RKK A;  3EU0 A;  2PBN A;  1Q6N A;  4WOH A;  2GJT A;  1NZ7 A;  1I9S A;  2A8B A;  4R0S A;  3O4S A;  2I3R A;  1LAR A;  4H1O A;  2OUD A;  2FH7 A;  1C86 A;  1U25 A;  2ZN7 A;  3OLR A;  1T4J A;  1YZ4 A;  2BGE A;  5KAC A;  3N0A A;  1PA1 A;  4GFU A;  1ZCL A;  1ONY A;  3D42 A;  5M43 A;  2Y96 A;  1AAX A;  1WAX A;  2GP0 A;  1BZH A;  1ZC0 A;  4AZ1 A;  1KAK A;  4I8N A;  2J16 A;  2QBR A;  2F6Z A;  5KAB A;  4RH5 A;  2Y2F A;  3EZZ A;  1GWZ A;  4KYR A;  4TVV A;  3QCG A;  3D1Q A;  3I36 A;  3SR9 A;  1XRI A;  5BZX A;  3V0G A;  4GS0 A;  1D5R A;  4ICZ A;  1NWL A;  2B4U A;  1T48 A;  1X24 A;  3S4O A;  2I6P A;  3EAX A;  1BZJ A;  2I6I A;  1PTT A;  4GE6 A;  2R0B A;  2AHS A;  1ZCK A;  3QCJ A;  5EHP A;  1PYN A;  2BZL A;  2NTA A;  3F9A A;  5K9V A;  5KA1 A;  4D3P A;  1KAV A;  2FJM A;  2Q05 A;  1QXK A;  2I1Y A;  2VEX A;  3V0E A;  2WGP A;  4GE2 A;  1FPR A;  5K25 A;  5K24 A;  2J16 B;  3D9C A;  2YDU A;  3ZM3 A;  4YAA A;  4ZRT A;  4PVG A;  4BJO A;  2H03 A;  2I6O A;  3LJ8 A;  2H4V A;  2PI7 A;  2P4D A;  3AWF A;  4RDD A;  4IKC A;  1V3A A;  4QUM A;  2F6V A;  4QBW A;  3GXH A;  3M4U A;  1NL9 A;  2IMG A;  3B7O A;  4GE5 A;  2SHP A;  2ESB A;  4JNB A;  5KA4 A;  2I42 A;  1YN9 A;  2QEP A;  1ECV A;  3ZM1 A;  1OHC A;  3OMH A;  4BPC A;  2CNF A;  4Y14 A;  1GFY A;  5I6V A;  1J4X A;  3F81 A;  1Q6J A;  1M3G A;  1LYV A;  4R0T A;  3BLU A;  1C88 A;  5J8R A;  3O3L A;  4NND A;  2M3V A;  5IBS A;  2AZR A;  2G59 A;  5KA2 A;  4JMK A;  5IBM A;  5AWX A;  1OEM X;  3V0I A;  3BRH A;  1A5Y A;  4RH9 A;  2JJD A;  4GWF A;  3ZM2 A;  2HY3 A;  2PSZ A;  4JMJ A;  2H04 A;  2NV5 A;  1G1H A;  2B3O A;  1I9T A;  3QCN A;  2F6F A;  1OEO X;  1XM2 A;  2OZ5 A;  2QCJ A;  4MBB A;  2MBC A;  1EEN A;  4H34 A;  1NWE A;  2B07 A;  1C84 A;  3MMJ A;  2I4G A;  1OET A;  2P6X A;  3I80 A;  3CM3 A;  2VEV A;  3MOZ A;  3S3K A;  1RPM A;  2B4P A;  3H2X A;  1FQ1 A;  2F70 A;  1PH0 A;  2NLK A;  2F71 A;  2A3K A;  3I7Z A;  2I4H A;  2VEU A;  2QDM A;  3QCH A;  4RI5 A;  2HVL A;  3QKQ A;  3F99 A;  3S4E A;  4D3R A;  1PA9 A;  2F6Y A;  5KA8 A;  3ZMQ A;  3V0F A;  1YFO A;  1OHE A;  2FJN A;  1Q6P A;  2CFV A;  2H02 A;  2NZ6 A;  4Z6B A;  5HDE A;  4OHI A;  2QDP A;  3QCF A;  1SUG A;  3O5X A;  5BZZ A;  3QCI A;  2F6T A;  5BUG A;  1YGU A;  3QKP A;  2CMA A;  1U24 A;  1ONZ A;  3O4T A;  4QAH A;  2CM8 A;  1ZZW A;  2CJZ A;  4R30 A;  4HJQ A;  4HRF A;  4RI4 A;  2B49 A;  2HXP A;  2Q47 A;  4OHH A;  4ERC A;  1G4W R;  1YGR A;  2BV5 A;  5LXQ B;  3BLT A;  3PS5 A;  3RO1 A;  3RGO A;  3D1O A;  2I6M A;  4KI9 A;  4OHD A;  2OOQ A;  3A5J A;  5KA0 A;  2CMC A;  1XBO A;  4WU3 A;  1VHR A;  2CNH A;  2HNQ A;  1YTN A;  4QUN A;  3V0H A;  3CWE A;  2NT2 A;  1BZC A;  3D1H A;  5EHR A;  3MOW A;  2CM2 A;  3NME A;  5MMZ B;  1L8K A;  1C87 A;  4QAP A;  2BIJ A;  2H4G A;  1OEV A;  2HC2 A;  4DGP A;  2E0T A;  3S3H A;  2NT7 A;  1YTS A;  4J51 A;  5KAD A;  3BM8 A;  1PTU A;  4DGX A;  5KA9 A;  4JBC A;  2PQ5 A;  2CNG A;  5K9W A;  3QCL A;  1PTY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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