4WOHA

Structure of of human dual-specificity phosphatase 22 (e24a/k28a/k30a/c88s) complexed with 4-nitrophenolphosphate
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
158
structure length
158
Chain Sequence
GGPMGNGMNKILPGLYIGNFKDARDAAQLSANAVTHILSVHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHSLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 22
total genus 64
structure length 158
sequence length 158
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2014-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4wohA01
2I6OA 1YGUA 3A5KA 5I6VA 3F9BA 2IMGA 1OHDA 3O4SA 4RH9A 3S3FA 2H4GA 3I80A 3RZ2A 1PTVA 5KADA 2I4EA 1JLNA 4JNBA 1ZC0A 3OMHA 2GP0A 4WU2A 5KA8A 2HC2A 4IKCA 5J8RA 4KYRA 1I9SA 2I6PA 3NMEA 4QBEA 1NZ7A 2CNEA 1XRIA 5BUGA 2CMBA 2G59A 4BJOA 2I4GA 4GRYA 2SHPA 1OEUA 1WRMA 1Q6TA 5AWXA 3D42A 2VEUA 2QDCA 2I3UA 5EHPA 1C84A 2J17A 2CNGA 4AZ1A 1PTYA 2HY3A 2I75A 1C85A 1G7GA 3S3EA 1T4JA 2I42A 1R6HA 1SUGA 2M3VA 2GJTA 4ICZA 2RF6A 1I57A 3ZM2A 1G1HA 3V0IA 2QCJA 1ECVA 4GE6A 4BPCA 2B4PA 4NX8A 1OEVA 3V0FA 1XBOA 2B4OA 1P15A 2H03A 1YWFA 2ZMMA 4GRZA 4NWFA 3AWEA 4PVGA 3D1OA 2B4SA 2BGDA 1PXHA 1V3AA 5KACA 2WGPA 3EU0A 2QCTA 2HVLA 2OUDA 3U96A 1D5RA 1YGRA 2J16B 5K9WA 3V0GA 3F9AA 2F6VA 2C7SA 3A5JA 3GXGA 2E0TA 3H2XA 3V0JA 1RPMA 5BX1A 3ZM0A 2CMCA 5KA7A 4Y14A 5BZZA 4YAAA 1T48A 2NT7A 1J4XA 1QXKA 4Y2EA 1U25A 1LARA 4QAPA 3LJ8A 5KAAA 1A5YA 1U24A 4H34A 3F81A 2PA5A 4NWGA 1PA1A 2P4DA 2JJDA 4OHHA 2QEPA 4S0GA 5EHRA 1PTUA 4JMKA 4KYQA 3ZMPA 3F99A 1NWEA 1AAXA 2CM2A 4GS0A 3S4OA 3QKQA 4DGXA 4WTYA 3QCEA 4H1OA 3OLRA 2QBSA 3EB1A 1G7FA 2Y2FA 2OZ5A 1OESA 2F6TA 1QZ0A 1PYNA 1RXDA 2NTAA 1C86A 2F46A 1C87A 1ZCLA 3V0EA 2I6IA 2PSZA 4GFVA 3D9CA 3MOWA 4YR8B 3EMUA 3S3HA 4RHGA 1I9TA 3CM3A 4RH5A 3BM8A 2GWOA 3O3LA 1XXVA 2A3KA 1G1GA 1YN9A 4RI4A 1FQ1A 1Q6NA 4JBCA 1OEOX 1FPRA 2F6ZA 4ZI4A 3O4TA 3O4UA 1YTNA 3O5XA 1LYVA 3QCKA 4R30A 1BZHA 5LXQB 3EZZA 3CWEA 3SMEA 3QCCA 1PH0A 1EENA 1PTTA 1Q1MA 2CNIA 1C88A 3MOZA 3QCDA 1X24A 2HCMA 2H04A 3M4UA 2HNQA 1WAXA 5M43A 2I5XA 5K9VA 1OHCA 2A8BA 2QBQA 1GFYA 1L8GA 4NNDA 2P6XA 4NYHA 5K24A 1G4US 4QBWA 2Q05A 2I6MA 2FH7A 3BLTA 1XM2A 3QCIA 1MKPA 5IBMA 4WU3A 3ZM1A 3V0HA 1NNYA 2B07A 1YFOA 3QCLA 4DGPA 2J16A 4R0TA 2HC1A 2HB1A 4ZN5A 1KAVA 2CJZA 3AWFA 2F6FA 4B04A 2OC3A 2H02A 4D3QA 1NL9A 1OETA 4GE2A 5KA1A 1Q6PA 2OOQA 2Q47A 3I7ZA 1G4WR 2CFVA 4WOHA 4RKKA 3S4EA 3S3KA 4D3RA 1M3GA 4RDDA 2ZN7A 3D1QA 2PQ5A 1YPTA 2B49A 2BGEA 4D3PA 4KI9A 2CMAA 2NV5A 1Q6JA 2F6YA 3SR9A 2AZRA 4HRFA 5KA2A 2F71A 1C83A 2HXPA 2CM3A 1U26A 4HJQA 1L8KA 3BRHA 4RI5A 2CM7A 2FJNA 4JMJA 2HNPA 5KA3A 2CNHA 1OEMX 2B4UA 1WCHA 2I1YA 1XXPA 2YDUA 3AWGA 1OHEA 2ESBA 1G1FA 2VEXA 2F6WA 2VEWA 3F41A 3ZV2A 4QUMA 5BZXA 2PBNA 5KA4A 3QCFA 1ZCKA 1ZZWA 3BLUA 5MMZB 2CNFA 1KAKA 1NWLA 3QCHA 1LQFA 3D44A 5K23A 2H4KA 1YTWA 3ZMQA 1Q6MA 4QUNA 4OHIA 1T49A 4OHLA 2MBCA 2H4VA 2Y96A 2I6JA 3PS5A 1YZ4A 2QBPA 5KA9A 3D1HA 4GWFA 2F70A 2C46A 3I36A 4PYHA 4I8NA 3RO1A 1Q6SA 5KABA 1PA9A 2G6ZA 3RGQA 5K25A 4HJPA 2BIJA 1VHRA 3B7OA 4Z6BA 2NLKA 2I4HA 2NZ6A 4GE5A 3RGOA 2VEYA 2R0BA 4ZRTA 2CM8A 1ONYA 2PT0A 3QCJA 2PI7A 2QDMA 3QCGA 1YTSA 2QBRA 3MMJA 5GTJA 5IBSA 2AHSA 3QCNA 3QCMA 3ZM3A 1ONZA 2B3OA 2VEVA 1NO6A 1GWZA 4OHEA 4TVVA 3EAXA 3V0DA 4QAHA 1FPZA 1BZCA 4MBBA 1EEOA 3GXHA 2BV5A 4OHDA 2DXPA 4GFUA 4J51A 5K22A 1JF7A 2QDPA 5KA0A 3QKPA 3N0AA 1BZJA 4ERCA 5HDEA 4R0SA 2FJMA 2BZLA 2NT2A 2I3RA 3QCBA
chains in the Genus database with same CATH superfamily
2I6OA 1YGUA 3A5KA 2GCAA 5I6VA 3F9BA 2IMGA 3PYZA 1OHDA 3O4SA 4RH9A 4C12A 3S3FA 2H4GA 2AM1A 3I80A 3RZ2A 1PTVA 5KADA 2I4EA 1JLNA 4JNBA 1ZC0A 3OMHA 2GP0A 2Y66A 4WU2A 5KA8A 2HC2A 4IKCA 1W7KA 5J8RA 1UAGA 4KYRA 1I9SA 2I6PA 3NMEA 4QBEA 1NZ7A 2CNEA 1XRIA 5BUGA 2CMBA 2G59A 4BJOA 2I4GA 4GRYA 2SHPA 1OEUA 1WRMA 1Q6TA 5AWXA 3D42A 2VEUA 2QDCA 2I3UA 5EHPA 1C84A 2J17A 2CNGA 4AZ1A 1PTYA 2HY3A 2I75A 4BUBA 1C85A 1G7GA 3S3EA 1T4JA 2VTDA 3HN7A 2I42A 4C13A 1R6HA 1SUGA 2M3VA 2GJTA 4ICZA 2JFHA 2RF6A 1I57A 3ZM2A 1G1HA 3V0IA 2QCJA 1ECVA 4GE6A 4CVLA 1GQQA 4BPCA 2B4PA 4NX8A 1OEVA 3V0FA 1XBOA 2B4OA 1P15A 2H03A 1YWFA 2ZMMA 1GG4A 4GRZA 3AWEA 4NWFA 4PVGA 3D1OA 1O5ZA 2B4SA 1PXHA 2BGDA 1V3AA 2F00A 5KACA 2WGPA 3EU0A 2QCTA 2HVLA 4BUCA 2OUDA 3U96A 1D5RA 1YGRA 2J16B 5K9WA 3V0GA 3F9AA 2F6VA 2C7SA 3A5JA 3GXGA 3ZM5A 2E0TA 3H2XA 3V0JA 1RPMA 5BX1A 3ZM0A 2CMCA 5KA7A 4Y14A 5BZZA 4YAAA 4QF5A 1T48A 2NT7A 1J4XA 1QXKA 4Y2EA 1U25A 1LARA 4QAPA 3LJ8A 5KAAA 2UUPA 1A5YA 1U24A 2AM2A 4H34A 3F81A 2PA5A 4NWGA 1PA1A 2P4DA 2JJDA 4OHHA 1P3DA 2QEPA 4S0GA 5EHRA 1PTUA 4JMKA 4KYQA 3ZMPA 3F99A 1NWEA 2GCBA 1AAXA 2CM2A 4GS0A 3S4OA 3QKQA 4DGXA 4WTYA 3QCEA 4H1OA 3OLRA 2QBSA 3EB1A 1G7FA 2Y2FA 1J6UA 1OESA 2OZ5A 2F6TA 1QZ0A 1PYNA 1RXDA 2NTAA 1C86A 2F46A 1C87A 1ZCLA 3V0EA 2I6IA 2PSZA 1P31A 4GFVA 3D9CA 3MOWA 4YR8B 5A5FA 1E0DA 3EMUA 3S3HA 4RHGA 1I9TA 3CM3A 4RH5A 3BM8A 2GWOA 3O3LA 1XXVA 2A3KA 1G1GA 2VOSA 1YN9A 4RI4A 1FQ1A 1Q6NA 4JBCA 1JBVA 1OEOX 1FPRA 2F6ZA 4ZI4A 3O4TA 2VTEA 3O4UA 3LK7A 1YTNA 3O5XA 1LYVA 3QCKA 4R30A 3UAGA 1BZHA 5LXQB 3EZZA 2WTZA 3CWEA 5A5EA 3SMEA 2JFGA 1E8CA 3QCCA 3N2AA 1PH0A 1EENA 1PTTA 1Q1MA 2CNIA 1C88A 3MOZA 3QCDA 1X24A 2HCMA 2H04A 3M4UA 3QCZA 2HNQA 1WAXA 5M43A 2GC5A 2I5XA 5K9VA 1OHCA 2A8BA 2QBQA 1GFYA 1L8GA 1W78A 2P6XA 4NNDA 4NYHA 5K24A 1G4US 4QBWA 2Q05A 2I6MA 2FH7A 3BLTA 1XM2A 3QCIA 1MKPA 5IBMA 2JFFA 4UAGA 4WU3A 3ZM1A 3V0HA 1NNYA 3ZM6A 2B07A 1YFOA 3QCLA 4DGPA 2J16A 4R0TA 2HC1A 2HB1A 4ZN5A 1KAVA 2CJZA 3AWFA 2F6FA 4B04A 2OC3A 2H02A 3ZL8A 4D3QA 1NL9A 1OETA 4GE2A 5KA1A 1Q6PA 2OOQA 2Q47A 3I7ZA 1G4WR 2CFVA 4WOHA 4RKKA 3S4EA 3S3KA 2Y68A 4D3RA 1FGSA 1M3GA 4RDDA 1JBWA 2ZN7A 3D1QA 2PQ5A 1YPTA 2Y1OA 2B49A 2WJPA 2BGEA 4D3PA 4KI9A 2CMAA 2NV5A 1Q6JA 2F6YA 3SR9A 3NRSA 2AZRA 4HRFA 5KA2A 2F71A 1C83A 2HXPA 2CM3A 1U26A 4HJQA 1GQYA 1L8KA 2Y67A 3BRHA 4RI5A 2CM7A 2FJNA 4JMJA 2HNPA 5KA3A 2CNHA 1OEMX 2B4UA 1WCHA 2I1YA 1XXPA 2YDUA 3AWGA 3MVNA 1OHEA 2ESBA 1G1FA 2VEXA 2F6WA 2VEWA 3F41A 3ZV2A 4QUMA 5BZXA 2PBNA 5KA4A 3QCFA 1ZCKA 1ZZWA 1EEHA 3BLUA 5MMZB 2CNFA 1KAKA 1NWLA 3QCHA 1LQFA 3D44A 5K23A 2H4KA 1YTWA 3ZMQA 1Q6MA 4QUNA 4OHIA 1T49A 4OHLA 2MBCA 2H4VA 2Y96A 2I6JA 3PS5A 1YZ4A 2QBPA 5KA9A 3D1HA 4GWFA 2F70A 4QDIA 2C46A 3I36A 4PYHA 4I8NA 3RO1A 1Q6SA 5KABA 1PA9A 2G6ZA 3RGQA 5K25A 4HJPA 2BIJA 1VHRA 2XPCA 3B7OA 4Z6BA 2NLKA 4HV4A 2VORA 2I4HA 2NZ6A 4GE5A 3RGOA 2X5OA 2VEYA 2R0BA 4ZRTA 2CM8A 1ONYA 2GC6A 2PT0A 3QCJA 2PI7A 2QDMA 3QCGA 1YTSA 2QBRA 3MMJA 5GTJA 5IBSA 4CVMA 2AHSA 3QCNA 3QCMA 3ZM3A 1ONZA 2B3OA 2VEVA 1NO6A 1GWZA 4OHEA 4TVVA 3EAXA 3V0DA 4QAHA 1FPZA 1BZCA 4MBBA 4CVKA 2UAGA 1EEOA 3GXHA 2BV5A 4OHDA 2DXPA 4GFUA 4J51A 5K22A 1JF7A 2XJAA 2UUOA 2QDPA 4ZIYA 5KA0A 3QKPA 3N0AA 1BZJA 4ERCA 5HDEA 4R0SA 2FJMA 2BZLA 2NT2A 2I3RA 3QCBA
chains in the Genus database with same CATH topology
2I6OA 1YGUA 3A5KA 5I6VA 3F9BA 2IMGA 1OHDA 3O4SA 4RH9A 3S3FA 2H4GA 3I80A 3RZ2A 1PTVA 5KADA 2I4EA 1JLNA 4JNBA 1ZC0A 3OMHA 2GP0A 4WU2A 5KA8A 2HC2A 4IKCA 5J8RA 4KYRA 1I9SA 2I6PA 3NMEA 4QBEA 1NZ7A 2CNEA 1XRIA 5BUGA 2CMBA 2G59A 4BJOA 2I4GA 4GRYA 2SHPA 1OEUA 1WRMA 1Q6TA 5AWXA 3D42A 2VEUA 2QDCA 2I3UA 5EHPA 1C84A 2J17A 2CNGA 4AZ1A 1PTYA 2HY3A 2I75A 1C85A 1G7GA 3S3EA 1T4JA 2I42A 1R6HA 1SUGA 2M3VA 2GJTA 4ICZA 2RF6A 1I57A 3ZM2A 1G1HA 3V0IA 2QCJA 1ECVA 4GE6A 4BPCA 2B4PA 4NX8A 1OEVA 3V0FA 1XBOA 2B4OA 1P15A 2H03A 1YWFA 2ZMMA 4GRZA 4NWFA 3AWEA 4PVGA 3D1OA 2B4SA 2BGDA 1PXHA 1V3AA 5KACA 2WGPA 3EU0A 2QCTA 2HVLA 2OUDA 3U96A 1D5RA 1YGRA 2J16B 5K9WA 3V0GA 3F9AA 2F6VA 2C7SA 3A5JA 3GXGA 2E0TA 3H2XA 3V0JA 1RPMA 5BX1A 3ZM0A 2CMCA 5KA7A 4Y14A 5BZZA 4YAAA 1T48A 2NT7A 1J4XA 1QXKA 4Y2EA 1U25A 1LARA 4QAPA 3LJ8A 5KAAA 1A5YA 1U24A 4H34A 3F81A 2PA5A 4NWGA 1PA1A 2P4DA 2JJDA 4OHHA 2QEPA 4S0GA 5EHRA 1PTUA 4JMKA 4KYQA 3ZMPA 3F99A 1NWEA 1AAXA 2CM2A 4GS0A 3S4OA 3QKQA 4DGXA 4WTYA 3QCEA 4H1OA 3OLRA 2QBSA 3EB1A 1G7FA 2Y2FA 2OZ5A 1OESA 2F6TA 1QZ0A 1PYNA 1RXDA 2NTAA 1C86A 2F46A 1C87A 1ZCLA 3V0EA 2I6IA 2PSZA 4GFVA 3D9CA 3MOWA 4YR8B 3EMUA 3S3HA 4RHGA 1I9TA 3CM3A 4RH5A 3BM8A 2GWOA 3O3LA 1XXVA 2A3KA 1G1GA 1YN9A 4RI4A 1FQ1A 1Q6NA 4JBCA 1OEOX 1FPRA 2F6ZA 4ZI4A 3O4TA 3O4UA 1YTNA 3O5XA 1LYVA 3QCKA 4R30A 1BZHA 5LXQB 3EZZA 3CWEA 3SMEA 3QCCA 1PH0A 1EENA 1PTTA 1Q1MA 2CNIA 1C88A 3MOZA 3QCDA 1X24A 2HCMA 2H04A 3M4UA 2HNQA 1WAXA 5M43A 2I5XA 5K9VA 1OHCA 2A8BA 2QBQA 1GFYA 1L8GA 4NNDA 2P6XA 4NYHA 5K24A 1G4US 4QBWA 2Q05A 2I6MA 2FH7A 3BLTA 1XM2A 3QCIA 1MKPA 5IBMA 4WU3A 3ZM1A 3V0HA 1NNYA 2B07A 1YFOA 3QCLA 4DGPA 2J16A 4R0TA 2HC1A 2HB1A 4ZN5A 1KAVA 2CJZA 3AWFA 2F6FA 4B04A 2OC3A 2H02A 4D3QA 1NL9A 1OETA 4GE2A 5KA1A 1Q6PA 2OOQA 2Q47A 3I7ZA 1G4WR 2CFVA 4WOHA 4RKKA 3S4EA 3S3KA 4D3RA 1M3GA 4RDDA 2ZN7A 3D1QA 2PQ5A 1YPTA 2B49A 2BGEA 4D3PA 4KI9A 2CMAA 2NV5A 1Q6JA 2F6YA 3SR9A 2AZRA 4HRFA 5KA2A 2F71A 1C83A 2HXPA 2CM3A 1U26A 4HJQA 1L8KA 3BRHA 4RI5A 2CM7A 2FJNA 4JMJA 2HNPA 5KA3A 2CNHA 1OEMX 2B4UA 1WCHA 2I1YA 1XXPA 2YDUA 3AWGA 1OHEA 2ESBA 1G1FA 2VEXA 2F6WA 2VEWA 3F41A 3ZV2A 4QUMA 5BZXA 2PBNA 5KA4A 3QCFA 1ZCKA 1ZZWA 3BLUA 5MMZB 2CNFA 1KAKA 1NWLA 3QCHA 1LQFA 3D44A 5K23A 2H4KA 1YTWA 3ZMQA 1Q6MA 4QUNA 4OHIA 1T49A 4OHLA 2MBCA 2H4VA 2Y96A 2I6JA 3PS5A 1YZ4A 2QBPA 5KA9A 3D1HA 4GWFA 2F70A 2C46A 3I36A 4PYHA 4I8NA 3RO1A 1Q6SA 5KABA 1PA9A 2G6ZA 3RGQA 5K25A 4HJPA 2BIJA 1VHRA 3B7OA 4Z6BA 2NLKA 2I4HA 2NZ6A 4GE5A 3RGOA 2VEYA 2R0BA 4ZRTA 2CM8A 1ONYA 2PT0A 3QCJA 2PI7A 2QDMA 3QCGA 1YTSA 2QBRA 3MMJA 5GTJA 5IBSA 2AHSA 3QCNA 3QCMA 3ZM3A 1ONZA 2B3OA 2VEVA 1NO6A 1GWZA 4OHEA 4TVVA 3EAXA 3V0DA 4QAHA 1FPZA 1BZCA 4MBBA 1EEOA 3GXHA 2BV5A 4OHDA 2DXPA 4GFUA 4J51A 5K22A 1JF7A 2QDPA 5KA0A 3QKPA 3N0AA 1BZJA 4ERCA 5HDEA 4R0SA 2FJMA 2BZLA 2NT2A 2I3RA 3QCBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I6O A;  1YGU A;  3A5K A;  5I6V A;  3F9B A;  2IMG A;  1OHD A;  3O4S A;  4RH9 A;  3S3F A;  2H4G A;  3I80 A;  3RZ2 A;  1PTV A;  5KAD A;  2I4E A;  1JLN A;  4JNB A;  1ZC0 A;  3OMH A;  2GP0 A;  4WU2 A;  5KA8 A;  2HC2 A;  4IKC A;  5J8R A;  4KYR A;  1I9S A;  2I6P A;  3NME A;  4QBE A;  1NZ7 A;  2CNE A;  1XRI A;  5BUG A;  2CMB A;  2G59 A;  4BJO A;  2I4G A;  4GRY A;  2SHP A;  1OEU A;  1WRM A;  1Q6T A;  5AWX A;  3D42 A;  2VEU A;  2QDC A;  2I3U A;  5EHP A;  1C84 A;  2J17 A;  2CNG A;  4AZ1 A;  1PTY A;  2HY3 A;  2I75 A;  1C85 A;  1G7G A;  3S3E A;  1T4J A;  2I42 A;  1R6H A;  1SUG A;  2M3V A;  2GJT A;  4ICZ A;  2RF6 A;  1I57 A;  3ZM2 A;  1G1H A;  3V0I A;  2QCJ A;  1ECV A;  4GE6 A;  4BPC A;  2B4P A;  4NX8 A;  1OEV A;  3V0F A;  1XBO A;  2B4O A;  1P15 A;  2H03 A;  1YWF A;  2ZMM A;  4GRZ A;  4NWF A;  3AWE A;  4PVG A;  3D1O A;  2B4S A;  2BGD A;  1PXH A;  1V3A A;  5KAC A;  2WGP A;  3EU0 A;  2QCT A;  2HVL A;  2OUD A;  3U96 A;  1D5R A;  1YGR A;  2J16 B;  5K9W A;  3V0G A;  3F9A A;  2F6V A;  2C7S A;  3A5J A;  3GXG A;  2E0T A;  3H2X A;  3V0J A;  1RPM A;  5BX1 A;  3ZM0 A;  2CMC A;  5KA7 A;  4Y14 A;  5BZZ A;  4YAA A;  1T48 A;  2NT7 A;  1J4X A;  1QXK A;  4Y2E A;  1U25 A;  1LAR A;  4QAP A;  3LJ8 A;  5KAA A;  1A5Y A;  1U24 A;  4H34 A;  3F81 A;  2PA5 A;  4NWG A;  1PA1 A;  2P4D A;  2JJD A;  4OHH A;  2QEP A;  4S0G A;  5EHR A;  1PTU A;  4JMK A;  4KYQ A;  3ZMP A;  3F99 A;  1NWE A;  1AAX A;  2CM2 A;  4GS0 A;  3S4O A;  3QKQ A;  4DGX A;  4WTY A;  3QCE A;  4H1O A;  3OLR A;  2QBS A;  3EB1 A;  1G7F A;  2Y2F A;  2OZ5 A;  1OES A;  2F6T A;  1QZ0 A;  1PYN A;  1RXD A;  2NTA A;  1C86 A;  2F46 A;  1C87 A;  1ZCL A;  3V0E A;  2I6I A;  2PSZ A;  4GFV A;  3D9C A;  3MOW A;  4YR8 B;  3EMU A;  3S3H A;  4RHG A;  1I9T A;  3CM3 A;  4RH5 A;  3BM8 A;  2GWO A;  3O3L A;  1XXV A;  2A3K A;  1G1G A;  1YN9 A;  4RI4 A;  1FQ1 A;  1Q6N A;  4JBC A;  1OEO X;  1FPR A;  2F6Z A;  4ZI4 A;  3O4T A;  3O4U A;  1YTN A;  3O5X A;  1LYV A;  3QCK A;  4R30 A;  1BZH A;  5LXQ B;  3EZZ A;  3CWE A;  3SME A;  3QCC A;  1PH0 A;  1EEN A;  1PTT A;  1Q1M A;  2CNI A;  1C88 A;  3MOZ A;  3QCD A;  1X24 A;  2HCM A;  2H04 A;  3M4U A;  2HNQ A;  1WAX A;  5M43 A;  2I5X A;  5K9V A;  1OHC A;  2A8B A;  2QBQ A;  1GFY A;  1L8G A;  4NND A;  2P6X A;  4NYH A;  5K24 A;  1G4U S;  4QBW A;  2Q05 A;  2I6M A;  2FH7 A;  3BLT A;  1XM2 A;  3QCI A;  1MKP A;  5IBM A;  4WU3 A;  3ZM1 A;  3V0H A;  1NNY A;  2B07 A;  1YFO A;  3QCL A;  4DGP A;  2J16 A;  4R0T A;  2HC1 A;  2HB1 A;  4ZN5 A;  1KAV A;  2CJZ A;  3AWF A;  2F6F A;  4B04 A;  2OC3 A;  2H02 A;  4D3Q A;  1NL9 A;  1OET A;  4GE2 A;  5KA1 A;  1Q6P A;  2OOQ A;  2Q47 A;  3I7Z A;  1G4W R;  2CFV A;  4WOH A;  4RKK A;  3S4E A;  3S3K A;  4D3R A;  1M3G A;  4RDD A;  2ZN7 A;  3D1Q A;  2PQ5 A;  1YPT A;  2B49 A;  2BGE A;  4D3P A;  4KI9 A;  2CMA A;  2NV5 A;  1Q6J A;  2F6Y A;  3SR9 A;  2AZR A;  4HRF A;  5KA2 A;  2F71 A;  1C83 A;  2HXP A;  2CM3 A;  1U26 A;  4HJQ A;  1L8K A;  3BRH A;  4RI5 A;  2CM7 A;  2FJN A;  4JMJ A;  2HNP A;  5KA3 A;  2CNH A;  1OEM X;  2B4U A;  1WCH A;  2I1Y A;  1XXP A;  2YDU A;  3AWG A;  1OHE A;  2ESB A;  1G1F A;  2VEX A;  2F6W A;  2VEW A;  3F41 A;  3ZV2 A;  4QUM A;  5BZX A;  2PBN A;  5KA4 A;  3QCF A;  1ZCK A;  1ZZW A;  3BLU A;  5MMZ B;  2CNF A;  1KAK A;  1NWL A;  3QCH A;  1LQF A;  3D44 A;  5K23 A;  2H4K A;  1YTW A;  3ZMQ A;  1Q6M A;  4QUN A;  4OHI A;  1T49 A;  4OHL A;  2MBC A;  2H4V A;  2Y96 A;  2I6J A;  3PS5 A;  1YZ4 A;  2QBP A;  5KA9 A;  3D1H A;  4GWF A;  2F70 A;  2C46 A;  3I36 A;  4PYH A;  4I8N A;  3RO1 A;  1Q6S A;  5KAB A;  1PA9 A;  2G6Z A;  3RGQ A;  5K25 A;  4HJP A;  2BIJ A;  1VHR A;  3B7O A;  4Z6B A;  2NLK A;  2I4H A;  2NZ6 A;  4GE5 A;  3RGO A;  2VEY A;  2R0B A;  4ZRT A;  2CM8 A;  1ONY A;  2PT0 A;  3QCJ A;  2PI7 A;  2QDM A;  3QCG A;  1YTS A;  2QBR A;  3MMJ A;  5GTJ A;  5IBS A;  2AHS A;  3QCN A;  3QCM A;  3ZM3 A;  1ONZ A;  2B3O A;  2VEV A;  1NO6 A;  1GWZ A;  4OHE A;  4TVV A;  3EAX A;  3V0D A;  4QAH A;  1FPZ A;  1BZC A;  4MBB A;  1EEO A;  3GXH A;  2BV5 A;  4OHD A;  2DXP A;  4GFU A;  4J51 A;  5K22 A;  1JF7 A;  2QDP A;  5KA0 A;  3QKP A;  3N0A A;  1BZJ A;  4ERC A;  5HDE A;  4R0S A;  2FJM A;  2BZL A;  2NT2 A;  2I3R A;  3QCB A; 
#chains in the Genus database with same CATH topology
 2I6O A;  1YGU A;  3A5K A;  2GCA A;  5I6V A;  3F9B A;  2IMG A;  3PYZ A;  1OHD A;  3O4S A;  4RH9 A;  4C12 A;  3S3F A;  2H4G A;  2AM1 A;  3I80 A;  3RZ2 A;  1PTV A;  5KAD A;  2I4E A;  1JLN A;  4JNB A;  1ZC0 A;  3OMH A;  2GP0 A;  2Y66 A;  4WU2 A;  5KA8 A;  2HC2 A;  4IKC A;  1W7K A;  5J8R A;  1UAG A;  4KYR A;  1I9S A;  2I6P A;  3NME A;  4QBE A;  1NZ7 A;  2CNE A;  1XRI A;  5BUG A;  2CMB A;  2G59 A;  4BJO A;  2I4G A;  4GRY A;  2SHP A;  1OEU A;  1WRM A;  1Q6T A;  5AWX A;  3D42 A;  2VEU A;  2QDC A;  2I3U A;  5EHP A;  1C84 A;  2J17 A;  2CNG A;  4AZ1 A;  1PTY A;  2HY3 A;  2I75 A;  4BUB A;  1C85 A;  1G7G A;  3S3E A;  1T4J A;  2VTD A;  3HN7 A;  2I42 A;  4C13 A;  1R6H A;  1SUG A;  2M3V A;  2GJT A;  4ICZ A;  2JFH A;  2RF6 A;  1I57 A;  3ZM2 A;  1G1H A;  3V0I A;  2QCJ A;  1ECV A;  4GE6 A;  4CVL A;  1GQQ A;  4BPC A;  2B4P A;  4NX8 A;  1OEV A;  3V0F A;  1XBO A;  2B4O A;  1P15 A;  2H03 A;  1YWF A;  2ZMM A;  1GG4 A;  4GRZ A;  3AWE A;  4NWF A;  4PVG A;  3D1O A;  1O5Z A;  2B4S A;  1PXH A;  2BGD A;  1V3A A;  2F00 A;  5KAC A;  2WGP A;  3EU0 A;  2QCT A;  2HVL A;  4BUC A;  2OUD A;  3U96 A;  1D5R A;  1YGR A;  2J16 B;  5K9W A;  3V0G A;  3F9A A;  2F6V A;  2C7S A;  3A5J A;  3GXG A;  3ZM5 A;  2E0T A;  3H2X A;  3V0J A;  1RPM A;  5BX1 A;  3ZM0 A;  2CMC A;  5KA7 A;  4Y14 A;  5BZZ A;  4YAA A;  4QF5 A;  1T48 A;  2NT7 A;  1J4X A;  1QXK A;  4Y2E A;  1U25 A;  1LAR A;  4QAP A;  3LJ8 A;  5KAA A;  2UUP A;  1A5Y A;  1U24 A;  2AM2 A;  4H34 A;  3F81 A;  2PA5 A;  4NWG A;  1PA1 A;  2P4D A;  2JJD A;  4OHH A;  1P3D A;  2QEP A;  4S0G A;  5EHR A;  1PTU A;  4JMK A;  4KYQ A;  3ZMP A;  3F99 A;  1NWE A;  2GCB A;  1AAX A;  2CM2 A;  4GS0 A;  3S4O A;  3QKQ A;  4DGX A;  4WTY A;  3QCE A;  4H1O A;  3OLR A;  2QBS A;  3EB1 A;  1G7F A;  2Y2F A;  1J6U A;  1OES A;  2OZ5 A;  2F6T A;  1QZ0 A;  1PYN A;  1RXD A;  2NTA A;  1C86 A;  2F46 A;  1C87 A;  1ZCL A;  3V0E A;  2I6I A;  2PSZ A;  1P31 A;  4GFV A;  3D9C A;  3MOW A;  4YR8 B;  5A5F A;  1E0D A;  3EMU A;  3S3H A;  4RHG A;  1I9T A;  3CM3 A;  4RH5 A;  3BM8 A;  2GWO A;  3O3L A;  1XXV A;  2A3K A;  1G1G A;  2VOS A;  1YN9 A;  4RI4 A;  1FQ1 A;  1Q6N A;  4JBC A;  1JBV A;  1OEO X;  1FPR A;  2F6Z A;  4ZI4 A;  3O4T A;  2VTE A;  3O4U A;  3LK7 A;  1YTN A;  3O5X A;  1LYV A;  3QCK A;  4R30 A;  3UAG A;  1BZH A;  5LXQ B;  3EZZ A;  2WTZ A;  3CWE A;  5A5E A;  3SME A;  2JFG A;  1E8C A;  3QCC A;  3N2A A;  1PH0 A;  1EEN A;  1PTT A;  1Q1M A;  2CNI A;  1C88 A;  3MOZ A;  3QCD A;  1X24 A;  2HCM A;  2H04 A;  3M4U A;  3QCZ A;  2HNQ A;  1WAX A;  5M43 A;  2GC5 A;  2I5X A;  5K9V A;  1OHC A;  2A8B A;  2QBQ A;  1GFY A;  1L8G A;  1W78 A;  2P6X A;  4NND A;  4NYH A;  5K24 A;  1G4U S;  4QBW A;  2Q05 A;  2I6M A;  2FH7 A;  3BLT A;  1XM2 A;  3QCI A;  1MKP A;  5IBM A;  2JFF A;  4UAG A;  4WU3 A;  3ZM1 A;  3V0H A;  1NNY A;  3ZM6 A;  2B07 A;  1YFO A;  3QCL A;  4DGP A;  2J16 A;  4R0T A;  2HC1 A;  2HB1 A;  4ZN5 A;  1KAV A;  2CJZ A;  3AWF A;  2F6F A;  4B04 A;  2OC3 A;  2H02 A;  3ZL8 A;  4D3Q A;  1NL9 A;  1OET A;  4GE2 A;  5KA1 A;  1Q6P A;  2OOQ A;  2Q47 A;  3I7Z A;  1G4W R;  2CFV A;  4WOH A;  4RKK A;  3S4E A;  3S3K A;  2Y68 A;  4D3R A;  1FGS A;  1M3G A;  4RDD A;  1JBW A;  2ZN7 A;  3D1Q A;  2PQ5 A;  1YPT A;  2Y1O A;  2B49 A;  2WJP A;  2BGE A;  4D3P A;  4KI9 A;  2CMA A;  2NV5 A;  1Q6J A;  2F6Y A;  3SR9 A;  3NRS A;  2AZR A;  4HRF A;  5KA2 A;  2F71 A;  1C83 A;  2HXP A;  2CM3 A;  1U26 A;  4HJQ A;  1GQY A;  1L8K A;  2Y67 A;  3BRH A;  4RI5 A;  2CM7 A;  2FJN A;  4JMJ A;  2HNP A;  5KA3 A;  2CNH A;  1OEM X;  2B4U A;  1WCH A;  2I1Y A;  1XXP A;  2YDU A;  3AWG A;  3MVN A;  1OHE A;  2ESB A;  1G1F A;  2VEX A;  2F6W A;  2VEW A;  3F41 A;  3ZV2 A;  4QUM A;  5BZX A;  2PBN A;  5KA4 A;  3QCF A;  1ZCK A;  1ZZW A;  1EEH A;  3BLU A;  5MMZ B;  2CNF A;  1KAK A;  1NWL A;  3QCH A;  1LQF A;  3D44 A;  5K23 A;  2H4K A;  1YTW A;  3ZMQ A;  1Q6M A;  4QUN A;  4OHI A;  1T49 A;  4OHL A;  2MBC A;  2H4V A;  2Y96 A;  2I6J A;  3PS5 A;  1YZ4 A;  2QBP A;  5KA9 A;  3D1H A;  4GWF A;  2F70 A;  4QDI A;  2C46 A;  3I36 A;  4PYH A;  4I8N A;  3RO1 A;  1Q6S A;  5KAB A;  1PA9 A;  2G6Z A;  3RGQ A;  5K25 A;  4HJP A;  2BIJ A;  1VHR A;  2XPC A;  3B7O A;  4Z6B A;  2NLK A;  4HV4 A;  2VOR A;  2I4H A;  2NZ6 A;  4GE5 A;  3RGO A;  2X5O A;  2VEY A;  2R0B A;  4ZRT A;  2CM8 A;  1ONY A;  2GC6 A;  2PT0 A;  3QCJ A;  2PI7 A;  2QDM A;  3QCG A;  1YTS A;  2QBR A;  3MMJ A;  5GTJ A;  5IBS A;  4CVM A;  2AHS A;  3QCN A;  3QCM A;  3ZM3 A;  1ONZ A;  2B3O A;  2VEV A;  1NO6 A;  1GWZ A;  4OHE A;  4TVV A;  3EAX A;  3V0D A;  4QAH A;  1FPZ A;  1BZC A;  4MBB A;  4CVK A;  2UAG A;  1EEO A;  3GXH A;  2BV5 A;  4OHD A;  2DXP A;  4GFU A;  4J51 A;  5K22 A;  1JF7 A;  2XJA A;  2UUO A;  2QDP A;  4ZIY A;  5KA0 A;  3QKP A;  3N0A A;  1BZJ A;  4ERC A;  5HDE A;  4R0S A;  2FJM A;  2BZL A;  2NT2 A;  2I3R A;  3QCB A; 
#chains in the Genus database with same CATH homology
 2I6O A;  1YGU A;  3A5K A;  5I6V A;  3F9B A;  2IMG A;  1OHD A;  3O4S A;  4RH9 A;  3S3F A;  2H4G A;  3I80 A;  3RZ2 A;  1PTV A;  5KAD A;  2I4E A;  1JLN A;  4JNB A;  1ZC0 A;  3OMH A;  2GP0 A;  4WU2 A;  5KA8 A;  2HC2 A;  4IKC A;  5J8R A;  4KYR A;  1I9S A;  2I6P A;  3NME A;  4QBE A;  1NZ7 A;  2CNE A;  1XRI A;  5BUG A;  2CMB A;  2G59 A;  4BJO A;  2I4G A;  4GRY A;  2SHP A;  1OEU A;  1WRM A;  1Q6T A;  5AWX A;  3D42 A;  2VEU A;  2QDC A;  2I3U A;  5EHP A;  1C84 A;  2J17 A;  2CNG A;  4AZ1 A;  1PTY A;  2HY3 A;  2I75 A;  1C85 A;  1G7G A;  3S3E A;  1T4J A;  2I42 A;  1R6H A;  1SUG A;  2M3V A;  2GJT A;  4ICZ A;  2RF6 A;  1I57 A;  3ZM2 A;  1G1H A;  3V0I A;  2QCJ A;  1ECV A;  4GE6 A;  4BPC A;  2B4P A;  4NX8 A;  1OEV A;  3V0F A;  1XBO A;  2B4O A;  1P15 A;  2H03 A;  1YWF A;  2ZMM A;  4GRZ A;  4NWF A;  3AWE A;  4PVG A;  3D1O A;  2B4S A;  2BGD A;  1PXH A;  1V3A A;  5KAC A;  2WGP A;  3EU0 A;  2QCT A;  2HVL A;  2OUD A;  3U96 A;  1D5R A;  1YGR A;  2J16 B;  5K9W A;  3V0G A;  3F9A A;  2F6V A;  2C7S A;  3A5J A;  3GXG A;  2E0T A;  3H2X A;  3V0J A;  1RPM A;  5BX1 A;  3ZM0 A;  2CMC A;  5KA7 A;  4Y14 A;  5BZZ A;  4YAA A;  1T48 A;  2NT7 A;  1J4X A;  1QXK A;  4Y2E A;  1U25 A;  1LAR A;  4QAP A;  3LJ8 A;  5KAA A;  1A5Y A;  1U24 A;  4H34 A;  3F81 A;  2PA5 A;  4NWG A;  1PA1 A;  2P4D A;  2JJD A;  4OHH A;  2QEP A;  4S0G A;  5EHR A;  1PTU A;  4JMK A;  4KYQ A;  3ZMP A;  3F99 A;  1NWE A;  1AAX A;  2CM2 A;  4GS0 A;  3S4O A;  3QKQ A;  4DGX A;  4WTY A;  3QCE A;  4H1O A;  3OLR A;  2QBS A;  3EB1 A;  1G7F A;  2Y2F A;  2OZ5 A;  1OES A;  2F6T A;  1QZ0 A;  1PYN A;  1RXD A;  2NTA A;  1C86 A;  2F46 A;  1C87 A;  1ZCL A;  3V0E A;  2I6I A;  2PSZ A;  4GFV A;  3D9C A;  3MOW A;  4YR8 B;  3EMU A;  3S3H A;  4RHG A;  1I9T A;  3CM3 A;  4RH5 A;  3BM8 A;  2GWO A;  3O3L A;  1XXV A;  2A3K A;  1G1G A;  1YN9 A;  4RI4 A;  1FQ1 A;  1Q6N A;  4JBC A;  1OEO X;  1FPR A;  2F6Z A;  4ZI4 A;  3O4T A;  3O4U A;  1YTN A;  3O5X A;  1LYV A;  3QCK A;  4R30 A;  1BZH A;  5LXQ B;  3EZZ A;  3CWE A;  3SME A;  3QCC A;  1PH0 A;  1EEN A;  1PTT A;  1Q1M A;  2CNI A;  1C88 A;  3MOZ A;  3QCD A;  1X24 A;  2HCM A;  2H04 A;  3M4U A;  2HNQ A;  1WAX A;  5M43 A;  2I5X A;  5K9V A;  1OHC A;  2A8B A;  2QBQ A;  1GFY A;  1L8G A;  4NND A;  2P6X A;  4NYH A;  5K24 A;  1G4U S;  4QBW A;  2Q05 A;  2I6M A;  2FH7 A;  3BLT A;  1XM2 A;  3QCI A;  1MKP A;  5IBM A;  4WU3 A;  3ZM1 A;  3V0H A;  1NNY A;  2B07 A;  1YFO A;  3QCL A;  4DGP A;  2J16 A;  4R0T A;  2HC1 A;  2HB1 A;  4ZN5 A;  1KAV A;  2CJZ A;  3AWF A;  2F6F A;  4B04 A;  2OC3 A;  2H02 A;  4D3Q A;  1NL9 A;  1OET A;  4GE2 A;  5KA1 A;  1Q6P A;  2OOQ A;  2Q47 A;  3I7Z A;  1G4W R;  2CFV A;  4WOH A;  4RKK A;  3S4E A;  3S3K A;  4D3R A;  1M3G A;  4RDD A;  2ZN7 A;  3D1Q A;  2PQ5 A;  1YPT A;  2B49 A;  2BGE A;  4D3P A;  4KI9 A;  2CMA A;  2NV5 A;  1Q6J A;  2F6Y A;  3SR9 A;  2AZR A;  4HRF A;  5KA2 A;  2F71 A;  1C83 A;  2HXP A;  2CM3 A;  1U26 A;  4HJQ A;  1L8K A;  3BRH A;  4RI5 A;  2CM7 A;  2FJN A;  4JMJ A;  2HNP A;  5KA3 A;  2CNH A;  1OEM X;  2B4U A;  1WCH A;  2I1Y A;  1XXP A;  2YDU A;  3AWG A;  1OHE A;  2ESB A;  1G1F A;  2VEX A;  2F6W A;  2VEW A;  3F41 A;  3ZV2 A;  4QUM A;  5BZX A;  2PBN A;  5KA4 A;  3QCF A;  1ZCK A;  1ZZW A;  3BLU A;  5MMZ B;  2CNF A;  1KAK A;  1NWL A;  3QCH A;  1LQF A;  3D44 A;  5K23 A;  2H4K A;  1YTW A;  3ZMQ A;  1Q6M A;  4QUN A;  4OHI A;  1T49 A;  4OHL A;  2MBC A;  2H4V A;  2Y96 A;  2I6J A;  3PS5 A;  1YZ4 A;  2QBP A;  5KA9 A;  3D1H A;  4GWF A;  2F70 A;  2C46 A;  3I36 A;  4PYH A;  4I8N A;  3RO1 A;  1Q6S A;  5KAB A;  1PA9 A;  2G6Z A;  3RGQ A;  5K25 A;  4HJP A;  2BIJ A;  1VHR A;  3B7O A;  4Z6B A;  2NLK A;  2I4H A;  2NZ6 A;  4GE5 A;  3RGO A;  2VEY A;  2R0B A;  4ZRT A;  2CM8 A;  1ONY A;  2PT0 A;  3QCJ A;  2PI7 A;  2QDM A;  3QCG A;  1YTS A;  2QBR A;  3MMJ A;  5GTJ A;  5IBS A;  2AHS A;  3QCN A;  3QCM A;  3ZM3 A;  1ONZ A;  2B3O A;  2VEV A;  1NO6 A;  1GWZ A;  4OHE A;  4TVV A;  3EAX A;  3V0D A;  4QAH A;  1FPZ A;  1BZC A;  4MBB A;  1EEO A;  3GXH A;  2BV5 A;  4OHD A;  2DXP A;  4GFU A;  4J51 A;  5K22 A;  1JF7 A;  2QDP A;  5KA0 A;  3QKP A;  3N0A A;  1BZJ A;  4ERC A;  5HDE A;  4R0S A;  2FJM A;  2BZL A;  2NT2 A;  2I3R A;  3QCB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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