4AZ1A

Crystal structure of the trypanosoma cruzi protein tyrosine phosphatase tcptp1, a potential therapeutic target for chagas' disease
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
298
structure length
294
Chain Sequence
DSNCFPFTKLSVQAQYERVQREFSLLLRQEDPRSISFATSLKNRHKNRYLDILANEATLYPQVTDSTPYYINGNLIDLDLPHKFVACQAPVVQGIPDFLAMLYEKKISLVIMVTKLEEGGFVKADRYWPEERGSGSIAVSGNCGLTISEDPGKAYEVEDELKITRRYLILQRADEPPHKFTQVQYTGWPDHGIPQSATSLEALLTNVKNSPTTVPVVVHCSAGIGRTGTLIGAYAALTHLERGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFVIYLTLMCRLGVDIKALVGLLN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Trypanosoma Cruzi Protein Tyrosine Phosphatase Tcptp1, a Potential Therapeutic Target for Chagas' Disease.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords TYROSINE SPECIFIC PROTEIN PHOSPHATASE
total genus 99
structure length 294
sequence length 298
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4az1A00
1FPRA 1BZJA 2QCJA 3AWFA 3GXGA 3S3FA 4ZN5A 5K23A 1I9SA 1NNYA 2NZ6A 4JNBA 1JLNA 1AAXA 1OHDA 3D44A 2B4SA 5KABA 3V0GA 4GWFA 1MKPA 4B04A 1PTTA 1BZHA 2I5XA 1I57A 3BLUA 5K22A 1Q6PA 1OEVA 1LARA 2J16B 4JMKA 4YAAA 4QBWA 5K9VA 2I4EA 4QAPA 4NWFA 2E0TA 2M3VA 2I6JA 1NO6A 5K25A 3QCGA 4RHGA 1I9TA 1G7GA 3S4OA 2VEWA 5K24A 3SR9A 2PA5A 2C46A 4RI4A 1PYNA 1FPZA 4OHEA 2HNPA 3EMUA 1YN9A 2I6IA 1WAXA 2B49A 2CNHA 5I6VA 4ZRTA 4KYQA 1JF7A 3F81A 2A8BA 2NT7A 3RGOA 1Q1MA 4MBBA 4RH5A 1C88A 3QCNA 1A5YA 3BRHA 3H2XA 3ZM0A 5KAAA 5KADA 5KA0A 5MMZB 2F6YA 4GRZA 3OLRA 3S4EA 3ZMPA 2H4KA 3I36A 2HCMA 4WTYA 3D42A 2SHPA 2H4GA 2A3KA 3GXHA 4H1OA 3V0IA 2RF6A 4R0TA 3A5KA 1G1FA 1YWFA 2DXPA 2H4VA 2Q47A 3D1HA 3O4SA 2MBCA 4GS0A 4QUNA 2CM8A 1YZ4A 4OHDA 2Y96A 2HB1A 1YTNA 4RDDA 3I7ZA 1OEMX 2F6VA 2WGPA 2BZLA 2HVLA 1EEOA 2OUDA 4OHLA 1G7FA 1G4US 2BGDA 1NL9A 3D9CA 3U96A 2PBNA 2B07A 2FJNA 2F6ZA 2F6FA 3OMHA 1OHEA 2ZN7A 4GRYA 2BV5A 1D5RA 2I42A 3O4TA 5KA7A 2P6XA 4RKKA 4DGXA 4NNDA 5KA8A 1YGRA 3RZ2A 2J16A 4RH9A 4HJPA 1OHCA 5KACA 2GJTA 3BM8A 2I3UA 5LXQB 1KAKA 3QCHA 3D1QA 3EB1A 2F6WA 2PSZA 2OC3A 5M43A 2NT2A 1V3AA 2HNQA 2VEXA 2VEUA 3O3LA 4HRFA 3QCJA 3V0FA 1U24A 4PVGA 1P15A 3EU0A 3CM3A 1Q6MA 1U25A 2B4UA 3MOWA 4ZI4A 1ZCKA 1G1HA 3B7OA 1YPTA 1VHRA 4TVVA 1RXDA 3SMEA 2OOQA 5EHRA 2I4HA 3QCKA 1T49A 5BUGA 4AZ1A 1R6HA 4HJQA 1XXVA 2I6MA 3ZMQA 1YTSA 1FQ1A 3ZV2A 4DGPA 2QEPA 4D3QA 4ERCA 2B3OA 2I1YA 2I75A 2G6ZA 2OZ5A 3ZM1A 2F46A 3QCMA 2CM3A 2HC2A 2QBSA 4ICZA 4Y2EA 2R0BA 1PTUA 1Q6SA 4BPCA 3EAXA 2F6TA 1XXPA 1C87A 2GP0A 1OETA 1ZZWA 2CNFA 3RGQA 1J4XA 3PS5A 3V0HA 4JMJA 2B4OA 3EZZA 2QDMA 4BJOA 3BLTA 2VEVA 5J8RA 1Q6NA 1PA1A 1YGUA 4RI5A 1T4JA 3S3KA 1PTVA 2B4PA 3QCDA 1PXHA 4NWGA 1Q6TA 3NMEA 1SUGA 3QCIA 1NZ7A 5AWXA 1XBOA 3LJ8A 5GTJA 5KA4A 2JJDA 3F99A 3MOZA 4S0GA 4GFUA 5KA1A 4QAHA 1Q6JA 1OESA 5IBSA 1RPMA 5BX1A 3I80A 4NX8A 1GFYA 3QKQA 1ONYA 4Z6BA 2Y2FA 2ZMMA 4GE5A 2QDPA 2AHSA 2PQ5A 2FJMA 2Q05A 2QCTA 3AWEA 2NV5A 5BZZA 2CFVA 4Y14A 4KYRA 2IMGA 1PH0A 2CM2A 4GFVA 1C83A 1OEUA 4PYHA 3QCEA 5HDEA 4H34A 3S3HA 1X24A 4QBEA 3V0JA 2CNIA 3ZM3A 2F70A 2GWOA 4GE6A 2I4GA 1QXKA 1LQFA 3O5XA 1YFOA 4OHIA 2AZRA 2H03A 4WU3A 3AWGA 2BGEA 2QBRA 4J51A 5EHPA 3MMJA 3V0DA 2CJZA 1NWEA 3F41A 1EENA 2HY3A 2CMCA 3O4UA 3M4UA 1G4WR 1ZCLA 1NWLA 1T48A 5KA9A 2QDCA 2FH7A 4R0SA 2HXPA 1PA9A 1C86A 4D3RA 4QUMA 4R30A 2NTAA 2QBPA 1C85A 3ZM2A 1C84A 2C7SA 4IKCA 3CWEA 1GWZA 2F71A 3QKPA 4KI9A 1U26A 1KAVA 1YTWA 3QCLA 4JBCA 3S3EA 3F9AA 3QCCA 4NYHA 3RO1A 2NLKA 3N0AA 5IBMA 1QZ0A 1PTYA 3D1OA 3F9BA 1ECVA 2VEYA 1M3GA 5K9WA 2CMAA 2G59A 2H02A 2HC1A 3QCBA 1BZCA 2CNGA 2QBQA 2YDUA 1L8GA 2H04A 3A5JA 2CNEA 4D3PA 1WCHA 2I6PA 2CMBA 2PI7A 2P4DA 4OHHA 1XM2A 3QCFA 1XRIA 1G1GA 4YR8B 5KA2A 1WRMA 3V0EA 2J17A 2I3RA 4I8NA 1LYVA 2BIJA 2I6OA 5KA3A 4WU2A 1ONZA 5BZXA 2CM7A 4WOHA 4GE2A 1ZC0A 1OEOX 2ESBA 2PT0A 1L8KA
chains in the Genus database with same CATH superfamily
1FPRA 1BZJA 2QCJA 3AWFA 3GXGA 3S3FA 4ZN5A 5K23A 1I9SA 1NNYA 2NZ6A 4CVLA 4JNBA 1JLNA 1AAXA 1OHDA 3D44A 2B4SA 5KABA 3V0GA 4GWFA 1MKPA 4B04A 1PTTA 2JFFA 1BZHA 2I5XA 1I57A 4QF5A 3BLUA 5K22A 1Q6PA 1OEVA 1LARA 2J16B 4JMKA 4YAAA 4QBWA 5K9VA 2I4EA 4QAPA 4NWFA 2E0TA 4ZIYA 2M3VA 2I6JA 2UAGA 1NO6A 5K25A 1J6UA 3QCGA 4RHGA 1I9TA 1G7GA 3S4OA 2VEWA 5K24A 3SR9A 2PA5A 4UAGA 2C46A 4RI4A 1PYNA 2GCAA 1FPZA 4OHEA 2HNPA 3EMUA 1YN9A 2I6IA 1WAXA 2B49A 2Y67A 2CNHA 5I6VA 4ZRTA 4KYQA 1JF7A 3F81A 2A8BA 2NT7A 3RGOA 1Q1MA 4MBBA 4RH5A 1C88A 3QCNA 1A5YA 3BRHA 3H2XA 3ZM0A 5KAAA 5KADA 5KA0A 5MMZB 3PYZA 2F6YA 4GRZA 3OLRA 3S4EA 3ZMPA 2H4KA 3I36A 2HCMA 1E8CA 4WTYA 1GG4A 3D42A 2SHPA 2H4GA 5A5EA 2A3KA 4CVKA 2VORA 3GXHA 4H1OA 3V0IA 2RF6A 4R0TA 2VTEA 3A5KA 1G1FA 1YWFA 2DXPA 2H4VA 2Q47A 1L8KA 3D1HA 3O4SA 2MBCA 4GS0A 4QUNA 2CM8A 1YZ4A 4OHDA 2Y96A 2HB1A 2XJAA 1YTNA 4RDDA 4BUCA 3I7ZA 1OEMX 4CVMA 2F6VA 2WGPA 2BZLA 2HVLA 1EEHA 1EEOA 2OUDA 4OHLA 2Y68A 1G7FA 1G4US 2BGDA 1NL9A 3D9CA 3U96A 2PBNA 2B07A 2FJNA 2F6ZA 2F6FA 3OMHA 1OHEA 2ZN7A 4GRYA 2BV5A 1D5RA 2I42A 2AM2A 3O4TA 5KA7A 2JFGA 2P6XA 4RKKA 4DGXA 4NNDA 5KA8A 1YGRA 3RZ2A 2J16A 4RH9A 4HJPA 1OHCA 5KACA 2GJTA 3BM8A 2I3UA 5LXQB 1KAKA 3QCHA 4HV4A 3D1QA 3EB1A 2F6WA 2PSZA 2OC3A 5M43A 2NT2A 1V3AA 2HNQA 3ZL8A 2VEXA 2VEUA 3O3LA 4C12A 4HRFA 3QCJA 3V0FA 1U24A 4PVGA 1P15A 3EU0A 3CM3A 1Q6MA 1U25A 2B4UA 3MOWA 4ZI4A 1ZCKA 1G1HA 3B7OA 1YPTA 1VHRA 4TVVA 1RXDA 3SMEA 2OOQA 5EHRA 2I4HA 3QCKA 1UAGA 3QCZA 3LK7A 1T49A 5BUGA 4AZ1A 1R6HA 4HJQA 1XXVA 2I6MA 3ZMQA 1YTSA 1FQ1A 3ZV2A 4DGPA 2QEPA 4D3QA 4ERCA 2B3OA 2I1YA 2VTDA 2I75A 3ZM5A 2G6ZA 2OZ5A 3ZM1A 2F46A 3QCMA 2CM3A 2HC2A 2Y66A 2QBSA 4ICZA 4Y2EA 2R0BA 1PTUA 1Q6SA 4BPCA 3EAXA 2F6TA 1XXPA 1C87A 2GP0A 1OETA 1ZZWA 2CNFA 3RGQA 2WJPA 2AM1A 1J4XA 3PS5A 3V0HA 4JMJA 2B4OA 3EZZA 4BUBA 2QDMA 4BJOA 3BLTA 2VEVA 5J8RA 1Q6NA 1PA1A 1YGUA 1O5ZA 4RI5A 1T4JA 3S3KA 1PTVA 2B4PA 3QCDA 1PXHA 4NWGA 1Q6TA 3NMEA 1SUGA 3QCIA 1NZ7A 5AWXA 1P31A 1XBOA 3LJ8A 3NRSA 5GTJA 3MVNA 5KA4A 2JJDA 3F99A 3MOZA 4S0GA 4GFUA 5KA1A 4QAHA 2GC6A 1Q6JA 1OESA 5IBSA 1RPMA 5BX1A 3I80A 4NX8A 2WTZA 1GFYA 3QKQA 1ONYA 4Z6BA 2Y2FA 2ZMMA 4GE5A 2QDPA 2AHSA 4QDIA 2PQ5A 2FJMA 1GQQA 2Q05A 2QCTA 2UUPA 3AWEA 2NV5A 5BZZA 2CFVA 4Y14A 4KYRA 2IMGA 1PH0A 2CM2A 4GFVA 1C83A 1OEUA 2X5OA 4PYHA 3HN7A 3QCEA 5HDEA 4H34A 3S3HA 1X24A 4QBEA 3V0JA 5A5FA 2CNIA 2F00A 2UUOA 2F70A 3ZM3A 2GWOA 4GE6A 2I4GA 1QXKA 1LQFA 3O5XA 1YFOA 1P3DA 2VOSA 4OHIA 2AZRA 2H03A 4WU3A 3AWGA 2BGEA 2QBRA 4J51A 5EHPA 3MMJA 3V0DA 2CJZA 1NWEA 1JBVA 3F41A 1EENA 1E0DA 2HY3A 2CMCA 3ZM6A 3O4UA 2GC5A 3M4UA 1G4WR 1ZCLA 1NWLA 1T48A 5KA9A 2QDCA 2FH7A 4R0SA 2HXPA 1PA9A 1C86A 4D3RA 4QUMA 4R30A 1JBWA 2NTAA 2QBPA 1C85A 3ZM2A 1C84A 2C7SA 4IKCA 3CWEA 4C13A 1GQYA 1GWZA 2F71A 2XPCA 3QKPA 4KI9A 1U26A 1KAVA 1YTWA 3QCLA 1FGSA 4JBCA 3S3EA 3F9AA 3QCCA 4NYHA 3RO1A 2NLKA 3N0AA 5IBMA 1QZ0A 1PTYA 3D1OA 3F9BA 1ECVA 2VEYA 1M3GA 5K9WA 2CMAA 2G59A 2H02A 2HC1A 3QCBA 1BZCA 2CNGA 2QBQA 2YDUA 1L8GA 2H04A 2JFHA 3A5JA 2CNEA 4D3PA 1WCHA 2I6PA 2CMBA 3N2AA 2PI7A 2P4DA 4OHHA 1XM2A 3QCFA 1XRIA 1G1GA 2GCBA 4YR8B 5KA2A 1WRMA 3V0EA 2J17A 2I3RA 4I8NA 2Y1OA 1LYVA 1W7KA 2BIJA 2I6OA 5KA3A 4WU2A 1ONZA 3UAGA 5BZXA 2CM7A 4WOHA 4GE2A 1ZC0A 1OEOX 2ESBA 2PT0A 1W78A
chains in the Genus database with same CATH topology
1FPRA 1BZJA 2QCJA 3AWFA 3GXGA 3S3FA 4ZN5A 5K23A 1I9SA 1NNYA 2NZ6A 4JNBA 1JLNA 1AAXA 1OHDA 3D44A 2B4SA 5KABA 3V0GA 4GWFA 1MKPA 4B04A 1PTTA 1BZHA 2I5XA 1I57A 3BLUA 5K22A 1Q6PA 1OEVA 1LARA 2J16B 4JMKA 4YAAA 4QBWA 5K9VA 2I4EA 4QAPA 4NWFA 2E0TA 2M3VA 2I6JA 1NO6A 5K25A 3QCGA 4RHGA 1I9TA 1G7GA 3S4OA 2VEWA 5K24A 3SR9A 2PA5A 2C46A 4RI4A 1PYNA 1FPZA 4OHEA 2HNPA 3EMUA 1YN9A 2I6IA 1WAXA 2B49A 2CNHA 5I6VA 4ZRTA 4KYQA 1JF7A 3F81A 2A8BA 2NT7A 3RGOA 1Q1MA 4MBBA 4RH5A 1C88A 3QCNA 1A5YA 3BRHA 3H2XA 3ZM0A 5KAAA 5KADA 5KA0A 5MMZB 2F6YA 4GRZA 3OLRA 3S4EA 3ZMPA 2H4KA 3I36A 2HCMA 4WTYA 3D42A 2SHPA 2H4GA 2A3KA 3GXHA 4H1OA 3V0IA 2RF6A 4R0TA 3A5KA 1G1FA 1YWFA 2DXPA 2H4VA 2Q47A 3D1HA 3O4SA 2MBCA 4GS0A 4QUNA 2CM8A 1YZ4A 4OHDA 2Y96A 2HB1A 1YTNA 4RDDA 3I7ZA 1OEMX 2F6VA 2WGPA 2BZLA 2HVLA 1EEOA 2OUDA 4OHLA 1G7FA 1G4US 2BGDA 1NL9A 3D9CA 3U96A 2PBNA 2B07A 2FJNA 2F6ZA 2F6FA 3OMHA 1OHEA 2ZN7A 4GRYA 2BV5A 1D5RA 2I42A 3O4TA 5KA7A 2P6XA 4RKKA 4DGXA 4NNDA 5KA8A 1YGRA 3RZ2A 2J16A 4RH9A 4HJPA 1OHCA 5KACA 2GJTA 3BM8A 2I3UA 5LXQB 1KAKA 3QCHA 3D1QA 3EB1A 2F6WA 2PSZA 2OC3A 5M43A 2NT2A 1V3AA 2HNQA 2VEXA 2VEUA 3O3LA 4HRFA 3QCJA 3V0FA 1U24A 4PVGA 1P15A 3EU0A 3CM3A 1Q6MA 1U25A 2B4UA 3MOWA 4ZI4A 1ZCKA 1G1HA 3B7OA 1YPTA 1VHRA 4TVVA 1RXDA 3SMEA 2OOQA 5EHRA 2I4HA 3QCKA 1T49A 5BUGA 4AZ1A 1R6HA 4HJQA 1XXVA 2I6MA 3ZMQA 1YTSA 1FQ1A 3ZV2A 4DGPA 2QEPA 4D3QA 4ERCA 2B3OA 2I1YA 2I75A 2G6ZA 2OZ5A 3ZM1A 2F46A 3QCMA 2CM3A 2HC2A 2QBSA 4ICZA 4Y2EA 2R0BA 1PTUA 1Q6SA 4BPCA 3EAXA 2F6TA 1XXPA 1C87A 2GP0A 1OETA 1ZZWA 2CNFA 3RGQA 1J4XA 3PS5A 3V0HA 4JMJA 2B4OA 3EZZA 2QDMA 4BJOA 3BLTA 2VEVA 5J8RA 1Q6NA 1PA1A 1YGUA 4RI5A 1T4JA 3S3KA 1PTVA 2B4PA 3QCDA 1PXHA 4NWGA 1Q6TA 3NMEA 1SUGA 3QCIA 1NZ7A 5AWXA 1XBOA 3LJ8A 5GTJA 5KA4A 2JJDA 3F99A 3MOZA 4S0GA 4GFUA 5KA1A 4QAHA 1Q6JA 1OESA 5IBSA 1RPMA 5BX1A 3I80A 4NX8A 1GFYA 3QKQA 1ONYA 4Z6BA 2Y2FA 2ZMMA 4GE5A 2QDPA 2AHSA 2PQ5A 2FJMA 2Q05A 2QCTA 3AWEA 2NV5A 5BZZA 2CFVA 4Y14A 4KYRA 2IMGA 1PH0A 2CM2A 4GFVA 1C83A 1OEUA 4PYHA 3QCEA 5HDEA 4H34A 3S3HA 1X24A 4QBEA 3V0JA 2CNIA 3ZM3A 2F70A 2GWOA 4GE6A 2I4GA 1QXKA 1LQFA 3O5XA 1YFOA 4OHIA 2AZRA 2H03A 4WU3A 3AWGA 2BGEA 2QBRA 4J51A 5EHPA 3MMJA 3V0DA 2CJZA 1NWEA 3F41A 1EENA 2HY3A 2CMCA 3O4UA 3M4UA 1G4WR 1ZCLA 1NWLA 1T48A 5KA9A 2QDCA 2FH7A 4R0SA 2HXPA 1PA9A 1C86A 4D3RA 4QUMA 4R30A 2NTAA 2QBPA 1C85A 3ZM2A 1C84A 2C7SA 4IKCA 3CWEA 1GWZA 2F71A 3QKPA 4KI9A 1U26A 1KAVA 1YTWA 3QCLA 4JBCA 3S3EA 3F9AA 3QCCA 4NYHA 3RO1A 2NLKA 3N0AA 5IBMA 1QZ0A 1PTYA 3D1OA 3F9BA 1ECVA 2VEYA 1M3GA 5K9WA 2CMAA 2G59A 2H02A 2HC1A 3QCBA 1BZCA 2CNGA 2QBQA 2YDUA 1L8GA 2H04A 3A5JA 2CNEA 4D3PA 1WCHA 2I6PA 2CMBA 2PI7A 2P4DA 4OHHA 1XM2A 3QCFA 1XRIA 1G1GA 4YR8B 5KA2A 1WRMA 3V0EA 2J17A 2I3RA 4I8NA 1LYVA 2BIJA 2I6OA 5KA3A 4WU2A 1ONZA 5BZXA 2CM7A 4WOHA 4GE2A 1ZC0A 1OEOX 2ESBA 2PT0A 1L8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FPR A;  1BZJ A;  2QCJ A;  3AWF A;  3GXG A;  3S3F A;  4ZN5 A;  5K23 A;  1I9S A;  1NNY A;  2NZ6 A;  4JNB A;  1JLN A;  1AAX A;  1OHD A;  3D44 A;  2B4S A;  5KAB A;  3V0G A;  4GWF A;  1MKP A;  4B04 A;  1PTT A;  1BZH A;  2I5X A;  1I57 A;  3BLU A;  5K22 A;  1Q6P A;  1OEV A;  1LAR A;  2J16 B;  4JMK A;  4YAA A;  4QBW A;  5K9V A;  2I4E A;  4QAP A;  4NWF A;  2E0T A;  2M3V A;  2I6J A;  1NO6 A;  5K25 A;  3QCG A;  4RHG A;  1I9T A;  1G7G A;  3S4O A;  2VEW A;  5K24 A;  3SR9 A;  2PA5 A;  2C46 A;  4RI4 A;  1PYN A;  1FPZ A;  4OHE A;  2HNP A;  3EMU A;  1YN9 A;  2I6I A;  1WAX A;  2B49 A;  2CNH A;  5I6V A;  4ZRT A;  4KYQ A;  1JF7 A;  3F81 A;  2A8B A;  2NT7 A;  3RGO A;  1Q1M A;  4MBB A;  4RH5 A;  1C88 A;  3QCN A;  1A5Y A;  3BRH A;  3H2X A;  3ZM0 A;  5KAA A;  5KAD A;  5KA0 A;  5MMZ B;  2F6Y A;  4GRZ A;  3OLR A;  3S4E A;  3ZMP A;  2H4K A;  3I36 A;  2HCM A;  4WTY A;  3D42 A;  2SHP A;  2H4G A;  2A3K A;  3GXH A;  4H1O A;  3V0I A;  2RF6 A;  4R0T A;  3A5K A;  1G1F A;  1YWF A;  2DXP A;  2H4V A;  2Q47 A;  3D1H A;  3O4S A;  2MBC A;  4GS0 A;  4QUN A;  2CM8 A;  1YZ4 A;  4OHD A;  2Y96 A;  2HB1 A;  1YTN A;  4RDD A;  3I7Z A;  1OEM X;  2F6V A;  2WGP A;  2BZL A;  2HVL A;  1EEO A;  2OUD A;  4OHL A;  1G7F A;  1G4U S;  2BGD A;  1NL9 A;  3D9C A;  3U96 A;  2PBN A;  2B07 A;  2FJN A;  2F6Z A;  2F6F A;  3OMH A;  1OHE A;  2ZN7 A;  4GRY A;  2BV5 A;  1D5R A;  2I42 A;  3O4T A;  5KA7 A;  2P6X A;  4RKK A;  4DGX A;  4NND A;  5KA8 A;  1YGR A;  3RZ2 A;  2J16 A;  4RH9 A;  4HJP A;  1OHC A;  5KAC A;  2GJT A;  3BM8 A;  2I3U A;  5LXQ B;  1KAK A;  3QCH A;  3D1Q A;  3EB1 A;  2F6W A;  2PSZ A;  2OC3 A;  5M43 A;  2NT2 A;  1V3A A;  2HNQ A;  2VEX A;  2VEU A;  3O3L A;  4HRF A;  3QCJ A;  3V0F A;  1U24 A;  4PVG A;  1P15 A;  3EU0 A;  3CM3 A;  1Q6M A;  1U25 A;  2B4U A;  3MOW A;  4ZI4 A;  1ZCK A;  1G1H A;  3B7O A;  1YPT A;  1VHR A;  4TVV A;  1RXD A;  3SME A;  2OOQ A;  5EHR A;  2I4H A;  3QCK A;  1T49 A;  5BUG A;  4AZ1 A;  1R6H A;  4HJQ A;  1XXV A;  2I6M A;  3ZMQ A;  1YTS A;  1FQ1 A;  3ZV2 A;  4DGP A;  2QEP A;  4D3Q A;  4ERC A;  2B3O A;  2I1Y A;  2I75 A;  2G6Z A;  2OZ5 A;  3ZM1 A;  2F46 A;  3QCM A;  2CM3 A;  2HC2 A;  2QBS A;  4ICZ A;  4Y2E A;  2R0B A;  1PTU A;  1Q6S A;  4BPC A;  3EAX A;  2F6T A;  1XXP A;  1C87 A;  2GP0 A;  1OET A;  1ZZW A;  2CNF A;  3RGQ A;  1J4X A;  3PS5 A;  3V0H A;  4JMJ A;  2B4O A;  3EZZ A;  2QDM A;  4BJO A;  3BLT A;  2VEV A;  5J8R A;  1Q6N A;  1PA1 A;  1YGU A;  4RI5 A;  1T4J A;  3S3K A;  1PTV A;  2B4P A;  3QCD A;  1PXH A;  4NWG A;  1Q6T A;  3NME A;  1SUG A;  3QCI A;  1NZ7 A;  5AWX A;  1XBO A;  3LJ8 A;  5GTJ A;  5KA4 A;  2JJD A;  3F99 A;  3MOZ A;  4S0G A;  4GFU A;  5KA1 A;  4QAH A;  1Q6J A;  1OES A;  5IBS A;  1RPM A;  5BX1 A;  3I80 A;  4NX8 A;  1GFY A;  3QKQ A;  1ONY A;  4Z6B A;  2Y2F A;  2ZMM A;  4GE5 A;  2QDP A;  2AHS A;  2PQ5 A;  2FJM A;  2Q05 A;  2QCT A;  3AWE A;  2NV5 A;  5BZZ A;  2CFV A;  4Y14 A;  4KYR A;  2IMG A;  1PH0 A;  2CM2 A;  4GFV A;  1C83 A;  1OEU A;  4PYH A;  3QCE A;  5HDE A;  4H34 A;  3S3H A;  1X24 A;  4QBE A;  3V0J A;  2CNI A;  3ZM3 A;  2F70 A;  2GWO A;  4GE6 A;  2I4G A;  1QXK A;  1LQF A;  3O5X A;  1YFO A;  4OHI A;  2AZR A;  2H03 A;  4WU3 A;  3AWG A;  2BGE A;  2QBR A;  4J51 A;  5EHP A;  3MMJ A;  3V0D A;  2CJZ A;  1NWE A;  3F41 A;  1EEN A;  2HY3 A;  2CMC A;  3O4U A;  3M4U A;  1G4W R;  1ZCL A;  1NWL A;  1T48 A;  5KA9 A;  2QDC A;  2FH7 A;  4R0S A;  2HXP A;  1PA9 A;  1C86 A;  4D3R A;  4QUM A;  4R30 A;  2NTA A;  2QBP A;  1C85 A;  3ZM2 A;  1C84 A;  2C7S A;  4IKC A;  3CWE A;  1GWZ A;  2F71 A;  3QKP A;  4KI9 A;  1U26 A;  1KAV A;  1YTW A;  3QCL A;  4JBC A;  3S3E A;  3F9A A;  3QCC A;  4NYH A;  3RO1 A;  2NLK A;  3N0A A;  5IBM A;  1QZ0 A;  1PTY A;  3D1O A;  3F9B A;  1ECV A;  2VEY A;  1M3G A;  5K9W A;  2CMA A;  2G59 A;  2H02 A;  2HC1 A;  3QCB A;  1BZC A;  2CNG A;  2QBQ A;  2YDU A;  1L8G A;  2H04 A;  3A5J A;  2CNE A;  4D3P A;  1WCH A;  2I6P A;  2CMB A;  2PI7 A;  2P4D A;  4OHH A;  1XM2 A;  3QCF A;  1XRI A;  1G1G A;  4YR8 B;  5KA2 A;  1WRM A;  3V0E A;  2J17 A;  2I3R A;  4I8N A;  1LYV A;  2BIJ A;  2I6O A;  5KA3 A;  4WU2 A;  1ONZ A;  5BZX A;  2CM7 A;  4WOH A;  4GE2 A;  1ZC0 A;  1OEO X;  2ESB A;  2PT0 A;  1L8K A; 
#chains in the Genus database with same CATH topology
 1FPR A;  1BZJ A;  2QCJ A;  3AWF A;  3GXG A;  3S3F A;  4ZN5 A;  5K23 A;  1I9S A;  1NNY A;  2NZ6 A;  4CVL A;  4JNB A;  1JLN A;  1AAX A;  1OHD A;  3D44 A;  2B4S A;  5KAB A;  3V0G A;  4GWF A;  1MKP A;  4B04 A;  1PTT A;  2JFF A;  1BZH A;  2I5X A;  1I57 A;  4QF5 A;  3BLU A;  5K22 A;  1Q6P A;  1OEV A;  1LAR A;  2J16 B;  4JMK A;  4YAA A;  4QBW A;  5K9V A;  2I4E A;  4QAP A;  4NWF A;  2E0T A;  4ZIY A;  2M3V A;  2I6J A;  2UAG A;  1NO6 A;  5K25 A;  1J6U A;  3QCG A;  4RHG A;  1I9T A;  1G7G A;  3S4O A;  2VEW A;  5K24 A;  3SR9 A;  2PA5 A;  4UAG A;  2C46 A;  4RI4 A;  1PYN A;  2GCA A;  1FPZ A;  4OHE A;  2HNP A;  3EMU A;  1YN9 A;  2I6I A;  1WAX A;  2B49 A;  2Y67 A;  2CNH A;  5I6V A;  4ZRT A;  4KYQ A;  1JF7 A;  3F81 A;  2A8B A;  2NT7 A;  3RGO A;  1Q1M A;  4MBB A;  4RH5 A;  1C88 A;  3QCN A;  1A5Y A;  3BRH A;  3H2X A;  3ZM0 A;  5KAA A;  5KAD A;  5KA0 A;  5MMZ B;  3PYZ A;  2F6Y A;  4GRZ A;  3OLR A;  3S4E A;  3ZMP A;  2H4K A;  3I36 A;  2HCM A;  1E8C A;  4WTY A;  1GG4 A;  3D42 A;  2SHP A;  2H4G A;  5A5E A;  2A3K A;  4CVK A;  2VOR A;  3GXH A;  4H1O A;  3V0I A;  2RF6 A;  4R0T A;  2VTE A;  3A5K A;  1G1F A;  1YWF A;  2DXP A;  2H4V A;  2Q47 A;  1L8K A;  3D1H A;  3O4S A;  2MBC A;  4GS0 A;  4QUN A;  2CM8 A;  1YZ4 A;  4OHD A;  2Y96 A;  2HB1 A;  2XJA A;  1YTN A;  4RDD A;  4BUC A;  3I7Z A;  1OEM X;  4CVM A;  2F6V A;  2WGP A;  2BZL A;  2HVL A;  1EEH A;  1EEO A;  2OUD A;  4OHL A;  2Y68 A;  1G7F A;  1G4U S;  2BGD A;  1NL9 A;  3D9C A;  3U96 A;  2PBN A;  2B07 A;  2FJN A;  2F6Z A;  2F6F A;  3OMH A;  1OHE A;  2ZN7 A;  4GRY A;  2BV5 A;  1D5R A;  2I42 A;  2AM2 A;  3O4T A;  5KA7 A;  2JFG A;  2P6X A;  4RKK A;  4DGX A;  4NND A;  5KA8 A;  1YGR A;  3RZ2 A;  2J16 A;  4RH9 A;  4HJP A;  1OHC A;  5KAC A;  2GJT A;  3BM8 A;  2I3U A;  5LXQ B;  1KAK A;  3QCH A;  4HV4 A;  3D1Q A;  3EB1 A;  2F6W A;  2PSZ A;  2OC3 A;  5M43 A;  2NT2 A;  1V3A A;  2HNQ A;  3ZL8 A;  2VEX A;  2VEU A;  3O3L A;  4C12 A;  4HRF A;  3QCJ A;  3V0F A;  1U24 A;  4PVG A;  1P15 A;  3EU0 A;  3CM3 A;  1Q6M A;  1U25 A;  2B4U A;  3MOW A;  4ZI4 A;  1ZCK A;  1G1H A;  3B7O A;  1YPT A;  1VHR A;  4TVV A;  1RXD A;  3SME A;  2OOQ A;  5EHR A;  2I4H A;  3QCK A;  1UAG A;  3QCZ A;  3LK7 A;  1T49 A;  5BUG A;  4AZ1 A;  1R6H A;  4HJQ A;  1XXV A;  2I6M A;  3ZMQ A;  1YTS A;  1FQ1 A;  3ZV2 A;  4DGP A;  2QEP A;  4D3Q A;  4ERC A;  2B3O A;  2I1Y A;  2VTD A;  2I75 A;  3ZM5 A;  2G6Z A;  2OZ5 A;  3ZM1 A;  2F46 A;  3QCM A;  2CM3 A;  2HC2 A;  2Y66 A;  2QBS A;  4ICZ A;  4Y2E A;  2R0B A;  1PTU A;  1Q6S A;  4BPC A;  3EAX A;  2F6T A;  1XXP A;  1C87 A;  2GP0 A;  1OET A;  1ZZW A;  2CNF A;  3RGQ A;  2WJP A;  2AM1 A;  1J4X A;  3PS5 A;  3V0H A;  4JMJ A;  2B4O A;  3EZZ A;  4BUB A;  2QDM A;  4BJO A;  3BLT A;  2VEV A;  5J8R A;  1Q6N A;  1PA1 A;  1YGU A;  1O5Z A;  4RI5 A;  1T4J A;  3S3K A;  1PTV A;  2B4P A;  3QCD A;  1PXH A;  4NWG A;  1Q6T A;  3NME A;  1SUG A;  3QCI A;  1NZ7 A;  5AWX A;  1P31 A;  1XBO A;  3LJ8 A;  3NRS A;  5GTJ A;  3MVN A;  5KA4 A;  2JJD A;  3F99 A;  3MOZ A;  4S0G A;  4GFU A;  5KA1 A;  4QAH A;  2GC6 A;  1Q6J A;  1OES A;  5IBS A;  1RPM A;  5BX1 A;  3I80 A;  4NX8 A;  2WTZ A;  1GFY A;  3QKQ A;  1ONY A;  4Z6B A;  2Y2F A;  2ZMM A;  4GE5 A;  2QDP A;  2AHS A;  4QDI A;  2PQ5 A;  2FJM A;  1GQQ A;  2Q05 A;  2QCT A;  2UUP A;  3AWE A;  2NV5 A;  5BZZ A;  2CFV A;  4Y14 A;  4KYR A;  2IMG A;  1PH0 A;  2CM2 A;  4GFV A;  1C83 A;  1OEU A;  2X5O A;  4PYH A;  3HN7 A;  3QCE A;  5HDE A;  4H34 A;  3S3H A;  1X24 A;  4QBE A;  3V0J A;  5A5F A;  2CNI A;  2F00 A;  2UUO A;  2F70 A;  3ZM3 A;  2GWO A;  4GE6 A;  2I4G A;  1QXK A;  1LQF A;  3O5X A;  1YFO A;  1P3D A;  2VOS A;  4OHI A;  2AZR A;  2H03 A;  4WU3 A;  3AWG A;  2BGE A;  2QBR A;  4J51 A;  5EHP A;  3MMJ A;  3V0D A;  2CJZ A;  1NWE A;  1JBV A;  3F41 A;  1EEN A;  1E0D A;  2HY3 A;  2CMC A;  3ZM6 A;  3O4U A;  2GC5 A;  3M4U A;  1G4W R;  1ZCL A;  1NWL A;  1T48 A;  5KA9 A;  2QDC A;  2FH7 A;  4R0S A;  2HXP A;  1PA9 A;  1C86 A;  4D3R A;  4QUM A;  4R30 A;  1JBW A;  2NTA A;  2QBP A;  1C85 A;  3ZM2 A;  1C84 A;  2C7S A;  4IKC A;  3CWE A;  4C13 A;  1GQY A;  1GWZ A;  2F71 A;  2XPC A;  3QKP A;  4KI9 A;  1U26 A;  1KAV A;  1YTW A;  3QCL A;  1FGS A;  4JBC A;  3S3E A;  3F9A A;  3QCC A;  4NYH A;  3RO1 A;  2NLK A;  3N0A A;  5IBM A;  1QZ0 A;  1PTY A;  3D1O A;  3F9B A;  1ECV A;  2VEY A;  1M3G A;  5K9W A;  2CMA A;  2G59 A;  2H02 A;  2HC1 A;  3QCB A;  1BZC A;  2CNG A;  2QBQ A;  2YDU A;  1L8G A;  2H04 A;  2JFH A;  3A5J A;  2CNE A;  4D3P A;  1WCH A;  2I6P A;  2CMB A;  3N2A A;  2PI7 A;  2P4D A;  4OHH A;  1XM2 A;  3QCF A;  1XRI A;  1G1G A;  2GCB A;  4YR8 B;  5KA2 A;  1WRM A;  3V0E A;  2J17 A;  2I3R A;  4I8N A;  2Y1O A;  1LYV A;  1W7K A;  2BIJ A;  2I6O A;  5KA3 A;  4WU2 A;  1ONZ A;  3UAG A;  5BZX A;  2CM7 A;  4WOH A;  4GE2 A;  1ZC0 A;  1OEO X;  2ESB A;  2PT0 A;  1W78 A; 
#chains in the Genus database with same CATH homology
 1FPR A;  1BZJ A;  2QCJ A;  3AWF A;  3GXG A;  3S3F A;  4ZN5 A;  5K23 A;  1I9S A;  1NNY A;  2NZ6 A;  4JNB A;  1JLN A;  1AAX A;  1OHD A;  3D44 A;  2B4S A;  5KAB A;  3V0G A;  4GWF A;  1MKP A;  4B04 A;  1PTT A;  1BZH A;  2I5X A;  1I57 A;  3BLU A;  5K22 A;  1Q6P A;  1OEV A;  1LAR A;  2J16 B;  4JMK A;  4YAA A;  4QBW A;  5K9V A;  2I4E A;  4QAP A;  4NWF A;  2E0T A;  2M3V A;  2I6J A;  1NO6 A;  5K25 A;  3QCG A;  4RHG A;  1I9T A;  1G7G A;  3S4O A;  2VEW A;  5K24 A;  3SR9 A;  2PA5 A;  2C46 A;  4RI4 A;  1PYN A;  1FPZ A;  4OHE A;  2HNP A;  3EMU A;  1YN9 A;  2I6I A;  1WAX A;  2B49 A;  2CNH A;  5I6V A;  4ZRT A;  4KYQ A;  1JF7 A;  3F81 A;  2A8B A;  2NT7 A;  3RGO A;  1Q1M A;  4MBB A;  4RH5 A;  1C88 A;  3QCN A;  1A5Y A;  3BRH A;  3H2X A;  3ZM0 A;  5KAA A;  5KAD A;  5KA0 A;  5MMZ B;  2F6Y A;  4GRZ A;  3OLR A;  3S4E A;  3ZMP A;  2H4K A;  3I36 A;  2HCM A;  4WTY A;  3D42 A;  2SHP A;  2H4G A;  2A3K A;  3GXH A;  4H1O A;  3V0I A;  2RF6 A;  4R0T A;  3A5K A;  1G1F A;  1YWF A;  2DXP A;  2H4V A;  2Q47 A;  3D1H A;  3O4S A;  2MBC A;  4GS0 A;  4QUN A;  2CM8 A;  1YZ4 A;  4OHD A;  2Y96 A;  2HB1 A;  1YTN A;  4RDD A;  3I7Z A;  1OEM X;  2F6V A;  2WGP A;  2BZL A;  2HVL A;  1EEO A;  2OUD A;  4OHL A;  1G7F A;  1G4U S;  2BGD A;  1NL9 A;  3D9C A;  3U96 A;  2PBN A;  2B07 A;  2FJN A;  2F6Z A;  2F6F A;  3OMH A;  1OHE A;  2ZN7 A;  4GRY A;  2BV5 A;  1D5R A;  2I42 A;  3O4T A;  5KA7 A;  2P6X A;  4RKK A;  4DGX A;  4NND A;  5KA8 A;  1YGR A;  3RZ2 A;  2J16 A;  4RH9 A;  4HJP A;  1OHC A;  5KAC A;  2GJT A;  3BM8 A;  2I3U A;  5LXQ B;  1KAK A;  3QCH A;  3D1Q A;  3EB1 A;  2F6W A;  2PSZ A;  2OC3 A;  5M43 A;  2NT2 A;  1V3A A;  2HNQ A;  2VEX A;  2VEU A;  3O3L A;  4HRF A;  3QCJ A;  3V0F A;  1U24 A;  4PVG A;  1P15 A;  3EU0 A;  3CM3 A;  1Q6M A;  1U25 A;  2B4U A;  3MOW A;  4ZI4 A;  1ZCK A;  1G1H A;  3B7O A;  1YPT A;  1VHR A;  4TVV A;  1RXD A;  3SME A;  2OOQ A;  5EHR A;  2I4H A;  3QCK A;  1T49 A;  5BUG A;  4AZ1 A;  1R6H A;  4HJQ A;  1XXV A;  2I6M A;  3ZMQ A;  1YTS A;  1FQ1 A;  3ZV2 A;  4DGP A;  2QEP A;  4D3Q A;  4ERC A;  2B3O A;  2I1Y A;  2I75 A;  2G6Z A;  2OZ5 A;  3ZM1 A;  2F46 A;  3QCM A;  2CM3 A;  2HC2 A;  2QBS A;  4ICZ A;  4Y2E A;  2R0B A;  1PTU A;  1Q6S A;  4BPC A;  3EAX A;  2F6T A;  1XXP A;  1C87 A;  2GP0 A;  1OET A;  1ZZW A;  2CNF A;  3RGQ A;  1J4X A;  3PS5 A;  3V0H A;  4JMJ A;  2B4O A;  3EZZ A;  2QDM A;  4BJO A;  3BLT A;  2VEV A;  5J8R A;  1Q6N A;  1PA1 A;  1YGU A;  4RI5 A;  1T4J A;  3S3K A;  1PTV A;  2B4P A;  3QCD A;  1PXH A;  4NWG A;  1Q6T A;  3NME A;  1SUG A;  3QCI A;  1NZ7 A;  5AWX A;  1XBO A;  3LJ8 A;  5GTJ A;  5KA4 A;  2JJD A;  3F99 A;  3MOZ A;  4S0G A;  4GFU A;  5KA1 A;  4QAH A;  1Q6J A;  1OES A;  5IBS A;  1RPM A;  5BX1 A;  3I80 A;  4NX8 A;  1GFY A;  3QKQ A;  1ONY A;  4Z6B A;  2Y2F A;  2ZMM A;  4GE5 A;  2QDP A;  2AHS A;  2PQ5 A;  2FJM A;  2Q05 A;  2QCT A;  3AWE A;  2NV5 A;  5BZZ A;  2CFV A;  4Y14 A;  4KYR A;  2IMG A;  1PH0 A;  2CM2 A;  4GFV A;  1C83 A;  1OEU A;  4PYH A;  3QCE A;  5HDE A;  4H34 A;  3S3H A;  1X24 A;  4QBE A;  3V0J A;  2CNI A;  3ZM3 A;  2F70 A;  2GWO A;  4GE6 A;  2I4G A;  1QXK A;  1LQF A;  3O5X A;  1YFO A;  4OHI A;  2AZR A;  2H03 A;  4WU3 A;  3AWG A;  2BGE A;  2QBR A;  4J51 A;  5EHP A;  3MMJ A;  3V0D A;  2CJZ A;  1NWE A;  3F41 A;  1EEN A;  2HY3 A;  2CMC A;  3O4U A;  3M4U A;  1G4W R;  1ZCL A;  1NWL A;  1T48 A;  5KA9 A;  2QDC A;  2FH7 A;  4R0S A;  2HXP A;  1PA9 A;  1C86 A;  4D3R A;  4QUM A;  4R30 A;  2NTA A;  2QBP A;  1C85 A;  3ZM2 A;  1C84 A;  2C7S A;  4IKC A;  3CWE A;  1GWZ A;  2F71 A;  3QKP A;  4KI9 A;  1U26 A;  1KAV A;  1YTW A;  3QCL A;  4JBC A;  3S3E A;  3F9A A;  3QCC A;  4NYH A;  3RO1 A;  2NLK A;  3N0A A;  5IBM A;  1QZ0 A;  1PTY A;  3D1O A;  3F9B A;  1ECV A;  2VEY A;  1M3G A;  5K9W A;  2CMA A;  2G59 A;  2H02 A;  2HC1 A;  3QCB A;  1BZC A;  2CNG A;  2QBQ A;  2YDU A;  1L8G A;  2H04 A;  3A5J A;  2CNE A;  4D3P A;  1WCH A;  2I6P A;  2CMB A;  2PI7 A;  2P4D A;  4OHH A;  1XM2 A;  3QCF A;  1XRI A;  1G1G A;  4YR8 B;  5KA2 A;  1WRM A;  3V0E A;  2J17 A;  2I3R A;  4I8N A;  1LYV A;  2BIJ A;  2I6O A;  5KA3 A;  4WU2 A;  1ONZ A;  5BZX A;  2CM7 A;  4WOH A;  4GE2 A;  1ZC0 A;  1OEO X;  2ESB A;  2PT0 A;  1L8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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