4GE5A

Crystal structure of human protein tyrosine phosphatase ptpn9 (meg2) complex with compound 5
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
307
structure length
298
Chain Sequence
SVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 9
total genus 97
structure length 298
sequence length 307
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2012-08-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4ge5A00
3D1QA 4H34A 1J4XA 3BRHA 2QEPA 4Y2EA 1FQ1A 2I6JA 2QDPA 1ONYA 3QCFA 4S0GA 2GWOA 3V0JA 3S3EA 3EAXA 1OHCA 1XM2A 1ZCLA 5J8RA 2P6XA 4KYQA 1KAVA 1AAXA 2R0BA 5K25A 5BZXA 2PBNA 1Q1MA 1XRIA 3F9BA 3F81A 1NWEA 2H02A 5K22A 4WU2A 1NL9A 2E0TA 4HJQA 2Q05A 2I42A 4IKCA 3ZMQA 1G7GA 1RXDA 4Y14A 1Q6PA 5EHPA 2HXPA 2OC3A 1LQFA 4R0TA 3I36A 4NX8A 3ZV2A 1R6HA 1OEOX 1WCHA 3ZM3A 2QBSA 1EENA 1PH0A 4GS0A 5BZZA 1U24A 2VEXA 1I57A 1YGUA 1C88A 3S3KA 4Z6BA 3QKPA 2I3RA 1PTUA 2AZRA 2I6PA 4B04A 1YFOA 3V0HA 4NNDA 2HC2A 2WGPA 3BLUA 1QZ0A 1Q6MA 1VHRA 2A8BA 2I1YA 2PSZA 2HNPA 2OUDA 2CM2A 5LXQB 1XBOA 2RF6A 3LJ8A 1WAXA 4GRYA 4OHIA 1YGRA 3AWEA 3O3LA 1SUGA 2FJNA 4BPCA 3QCEA 2G6ZA 2BV5A 3QKQA 3V0GA 1NZ7A 2F70A 2F6YA 3D9CA 2I75A 4KI9A 1ZCKA 4OHDA 2FH7A 5EHRA 3RO1A 1RPMA 5MMZB 2OOQA 5BX1A 2SHPA 4QBWA 2OZ5A 4OHHA 2ESBA 4ZN5A 4RKKA 2CNHA 1PYNA 4RH5A 2Y96A 2F6FA 2I6OA 4PYHA 1PA9A 2HCMA 1G4US 4GE5A 2BGEA 3OMHA 1U25A 3F9AA 4GE6A 2H4VA 1OETA 3CWEA 3QCGA 2F6WA 4MBBA 4BJOA 3S3HA 5KAAA 1OHDA 2J16B 4ZRTA 1I9TA 2HB1A 4KYRA 2CNFA 3D1OA 2CM7A 1G4WR 2B4SA 1PA1A 3AWGA 5K23A 2QDCA 3RGOA 4OHEA 4GE2A 4RHGA 4GFUA 3BLTA 2F6TA 3ZM0A 1PXHA 2ZMMA 1ZZWA 3A5JA 3I7ZA 2I4GA 2AHSA 2FJMA 4H1OA 4HJPA 5HDEA 2HY3A 2NLKA 3S3FA 3GXHA 1X24A 2H03A 1YTWA 1BZHA 2CMCA 4NYHA 4RDDA 2B4UA 2NT7A 5GTJA 1V3AA 3MOZA 3N0AA 3ZM1A 3V0IA 1PTVA 5K24A 1G7FA 1OESA 4TVVA 1ZC0A 5KACA 1OHEA 1GFYA 2HC1A 3EB1A 2H04A 4YAAA 1LYVA 2F71A 2PA5A 4ZI4A 1G1FA 4D3QA 2I3UA 3D44A 1M3GA 4PVGA 1JLNA 2GP0A 1T48A 2CJZA 3QCJA 3ZMPA 3QCIA 3QCBA 1EEOA 2B49A 1T4JA 2CNEA 3S4EA 3QCMA 2CFVA 1FPZA 1G1HA 3QCKA 3RGQA 4JBCA 1OEUA 2DXPA 5KA8A 2J17A 3EU0A 3V0FA 1C83A 4QBEA 1Q6NA 4DGXA 2HVLA 1LARA 2JJDA 5BUGA 3MMJA 1YTSA 2QCTA 2NV5A 3ZM2A 2QBPA 1L8GA 3D1HA 1YPTA 2QDMA 1C86A 5KA3A 2MBCA 1XXVA 1D5RA 2ZN7A 1NWLA 4I8NA 3I80A 4WU3A 1G1GA 3PS5A 3BM8A 2H4KA 3QCNA 2C7SA 3QCLA 2BGDA 2PQ5A 1Q6TA 5AWXA 4RH9A 4D3PA 5IBMA 1I9SA 1C84A 1JF7A 2CMAA 2Y2FA 1Q6JA 3V0EA 2F6VA 3U96A 4DGPA 2CMBA 1XXPA 4GWFA 5KADA 1PTTA 4D3RA 2VEUA 4QUMA 5K9VA 4WOHA 3QCHA 2I6IA 5KA7A 2PT0A 3QCDA 1MKPA 2I4HA 2IMGA 4QAPA 1QXKA 4JMJA 4QAHA 1GWZA 1BZCA 2VEVA 2M3VA 1BZJA 3O4SA 4RI5A 5K9WA 3A5KA 4AZ1A 1U26A 2I5XA 1NO6A 3O5XA 3H2XA 1C87A 2A3KA 5KA4A 2QCJA 4R30A 2CNGA 1OEMX 1NNYA 3CM3A 3F99A 2VEWA 1L8KA 4RI4A 3SR9A 4ICZA 3OLRA 1ECVA 4R0SA 2CM8A 5KA0A 3D42A 2CNIA 2G59A 2P4DA 4JNBA 5KA2A 2B4PA 1C85A 3EMUA 4NWFA 2B4OA 5KABA 2GJTA 2B3OA 1T49A 1YN9A 3S4OA 2B07A 2H4GA 1OEVA 4J51A 3SMEA 2YDUA 5KA1A 3B7OA 4WTYA 1Q6SA 5KA9A 2BZLA 2J16A 2I4EA 4NWGA 3F41A 3NMEA 5IBSA 3O4TA 3V0DA 1P15A 2C46A 2CM3A 2PI7A 2NTAA 5I6VA 2NT2A 2F46A 2I6MA 3AWFA 2BIJA 1KAKA 3M4UA 2VEYA 1ONZA 3QCCA 3O4UA 1YZ4A 4JMKA 3EZZA 5M43A 4YR8B 1PTYA 1A5YA 2NZ6A 4QUNA 1WRMA 1YWFA 4GRZA 2HNQA 1YTNA 2QBRA 2F6ZA 3GXGA 4OHLA 3RZ2A 2QBQA 3MOWA 4ERCA 1FPRA 4GFVA 2Q47A 4HRFA
chains in the Genus database with same CATH superfamily
3D1QA 2XJAA 4H34A 1J4XA 3BRHA 2QEPA 4Y2EA 1FQ1A 2I6JA 2QDPA 1ONYA 3QCFA 4S0GA 1UAGA 2GWOA 3V0JA 3S3EA 3EAXA 1OHCA 1XM2A 1ZCLA 5J8RA 2P6XA 3HN7A 2WJPA 4KYQA 4BUCA 1KAVA 4CVKA 2JFGA 1AAXA 2R0BA 4QDIA 5K25A 5BZXA 2PBNA 1Q1MA 1XRIA 2WTZA 2F00A 3F9BA 3F81A 1NWEA 2VTDA 2H02A 5K22A 4WU2A 1NL9A 2E0TA 4HJQA 2Q05A 2I42A 4IKCA 3ZMQA 1G7GA 1RXDA 4Y14A 1Q6PA 5EHPA 2HXPA 2OC3A 1LQFA 4R0TA 3I36A 4NX8A 3ZV2A 1R6HA 1OEOX 1WCHA 3ZM3A 2QBSA 1EENA 1PH0A 4GS0A 5BZZA 1U24A 2VEXA 1I57A 1YGUA 1C88A 3S3KA 4Z6BA 3QKPA 2I3RA 1PTUA 2AZRA 2I6PA 2UUPA 3LK7A 4B04A 1YFOA 3V0HA 4NNDA 2HC2A 2WGPA 3BLUA 1QZ0A 4QF5A 1Q6MA 1VHRA 2A8BA 2I1YA 2PSZA 2HNPA 2OUDA 2AM2A 2CM2A 5LXQB 1XBOA 2RF6A 3LJ8A 1WAXA 2VTEA 2XPCA 4GRYA 4OHIA 1YGRA 3AWEA 3O3LA 1SUGA 2FJNA 4BPCA 3QCEA 2G6ZA 2BV5A 3QKQA 3V0GA 1NZ7A 2F70A 2F6YA 3D9CA 2I75A 4KI9A 1ZCKA 4OHDA 1JBWA 2FH7A 5EHRA 2UAGA 3RO1A 2GCBA 1RPMA 5MMZB 2OOQA 5BX1A 2SHPA 4QBWA 2OZ5A 4OHHA 2ESBA 4ZN5A 4RKKA 2CNHA 1PYNA 4RH5A 2Y96A 2F6FA 2I6OA 4PYHA 1PA9A 2HCMA 1G4US 4GE5A 2BGEA 3OMHA 1U25A 3F9AA 4GE6A 2H4VA 1OETA 3CWEA 3QCGA 2F6WA 4MBBA 4BJOA 3S3HA 5KAAA 1OHDA 1E8CA 2J16B 4ZRTA 1I9TA 1E0DA 4HV4A 2HB1A 4KYRA 2CNFA 3D1OA 2CM7A 1G4WR 2B4SA 1PA1A 3AWGA 5K23A 2QDCA 3RGOA 2Y67A 4GE2A 4OHEA 4RHGA 4GFUA 3BLTA 2F6TA 3UAGA 3ZM0A 1PXHA 2ZMMA 1ZZWA 3A5JA 3I7ZA 4BUBA 2I4GA 2AHSA 2FJMA 4H1OA 4HJPA 5HDEA 2HY3A 2NLKA 4ZIYA 3S3FA 3GXHA 1X24A 2H03A 1YTWA 1BZHA 2CMCA 4NYHA 4RDDA 2B4UA 2NT7A 5GTJA 4CVMA 1V3AA 3MOZA 3N0AA 3ZM1A 3V0IA 1PTVA 5K24A 1G7FA 1OESA 4TVVA 1ZC0A 5KACA 3EB1A 1OHEA 1GFYA 2HC1A 2H04A 4YAAA 1LYVA 2F71A 1W78A 4CVLA 2PA5A 2Y1OA 1GQYA 2GCAA 1P31A 4ZI4A 1G1FA 4D3QA 2I3UA 3D44A 1M3GA 4PVGA 1JLNA 2GP0A 1T48A 2CJZA 3QCJA 3ZMPA 3QCIA 3QCBA 1EEOA 2B49A 1T4JA 2CNEA 3S4EA 3QCMA 2CFVA 1FPZA 1G1HA 3QCKA 3RGQA 4JBCA 1OEUA 2DXPA 5KA8A 1GG4A 2J17A 2Y68A 3EU0A 3V0FA 1JBVA 1C83A 4QBEA 1Q6NA 4DGXA 2HVLA 1LARA 2JJDA 5BUGA 3MMJA 1YTSA 2QCTA 2NV5A 3ZM2A 2QBPA 1L8GA 3D1HA 1YPTA 2QDMA 1C86A 5KA3A 2MBCA 1XXVA 1D5RA 2ZN7A 1NWLA 4I8NA 3I80A 4WU3A 1G1GA 3N2AA 3BM8A 3PS5A 2H4KA 3QCNA 2C7SA 3QCLA 2BGDA 2PQ5A 1Q6TA 5AWXA 4RH9A 4UAGA 4D3PA 5IBMA 1I9SA 1C84A 1JF7A 2CMAA 2Y2FA 1Q6JA 2VORA 3V0EA 2F6VA 3U96A 4DGPA 2CMBA 1XXPA 4GWFA 5A5EA 5KADA 1PTTA 1FGSA 4D3RA 2VEUA 4QUMA 5K9VA 4WOHA 3QCHA 2I6IA 5KA7A 2PT0A 3QCDA 4C13A 2Y66A 1MKPA 2I4HA 2IMGA 4QAPA 1QXKA 1O5ZA 2AM1A 4JMJA 4QAHA 3ZM6A 1GWZA 3ZM5A 1BZCA 2VEVA 2M3VA 1BZJA 2X5OA 3O4SA 4RI5A 5K9WA 3A5KA 4AZ1A 1U26A 2I5XA 1NO6A 3O5XA 3H2XA 1C87A 2A3KA 5KA4A 2QCJA 2GC6A 4R30A 2CNGA 1OEMX 1NNYA 3CM3A 3F99A 2VEWA 1L8KA 1W7KA 4RI4A 3SR9A 4ICZA 3OLRA 1ECVA 4R0SA 2CM8A 5KA0A 3D42A 5A5FA 2CNIA 2G59A 2P4DA 4JNBA 5KA2A 2B4PA 1C85A 3EMUA 4NWFA 2B4OA 5KABA 4C12A 2GJTA 2B3OA 1T49A 1YN9A 3S4OA 2B07A 2H4GA 1OEVA 4J51A 3SMEA 2YDUA 5KA1A 3NRSA 3B7OA 4WTYA 1Q6SA 5KA9A 2BZLA 2J16A 2I4EA 4NWGA 2JFFA 3QCZA 3F41A 3NMEA 1GQQA 5IBSA 3PYZA 3O4TA 3V0DA 1P15A 2C46A 2CM3A 2PI7A 2GC5A 2VOSA 2NTAA 3MVNA 5I6VA 2NT2A 2F46A 2I6MA 3AWFA 2BIJA 1KAKA 3M4UA 2JFHA 2VEYA 1ONZA 3ZL8A 3QCCA 1J6UA 3O4UA 1YZ4A 4JMKA 3EZZA 5M43A 4YR8B 1PTYA 1A5YA 2NZ6A 4QUNA 1EEHA 1WRMA 1YWFA 4GRZA 2HNQA 1YTNA 2QBRA 1P3DA 2F6ZA 2UUOA 3GXGA 4OHLA 3RZ2A 2QBQA 3MOWA 4ERCA 1FPRA 4GFVA 2Q47A 4HRFA
chains in the Genus database with same CATH topology
3D1QA 4H34A 1J4XA 3BRHA 2QEPA 4Y2EA 1FQ1A 2I6JA 2QDPA 1ONYA 3QCFA 4S0GA 2GWOA 3V0JA 3S3EA 3EAXA 1OHCA 1XM2A 1ZCLA 5J8RA 2P6XA 4KYQA 1KAVA 1AAXA 2R0BA 5K25A 5BZXA 2PBNA 1Q1MA 1XRIA 3F9BA 3F81A 1NWEA 2H02A 5K22A 4WU2A 1NL9A 2E0TA 4HJQA 2Q05A 2I42A 4IKCA 3ZMQA 1G7GA 1RXDA 4Y14A 1Q6PA 5EHPA 2HXPA 2OC3A 1LQFA 4R0TA 3I36A 4NX8A 3ZV2A 1R6HA 1OEOX 1WCHA 3ZM3A 2QBSA 1EENA 1PH0A 4GS0A 5BZZA 1U24A 2VEXA 1I57A 1YGUA 1C88A 3S3KA 4Z6BA 3QKPA 2I3RA 1PTUA 2AZRA 2I6PA 4B04A 1YFOA 3V0HA 4NNDA 2HC2A 2WGPA 3BLUA 1QZ0A 1Q6MA 1VHRA 2A8BA 2I1YA 2PSZA 2HNPA 2OUDA 2CM2A 5LXQB 1XBOA 2RF6A 3LJ8A 1WAXA 4GRYA 4OHIA 1YGRA 3AWEA 3O3LA 1SUGA 2FJNA 4BPCA 3QCEA 2G6ZA 2BV5A 3QKQA 3V0GA 1NZ7A 2F70A 2F6YA 3D9CA 2I75A 4KI9A 1ZCKA 4OHDA 2FH7A 5EHRA 3RO1A 1RPMA 5MMZB 2OOQA 5BX1A 2SHPA 4QBWA 2OZ5A 4OHHA 2ESBA 4ZN5A 4RKKA 2CNHA 1PYNA 4RH5A 2Y96A 2F6FA 2I6OA 4PYHA 1PA9A 2HCMA 1G4US 4GE5A 2BGEA 3OMHA 1U25A 3F9AA 4GE6A 2H4VA 1OETA 3CWEA 3QCGA 2F6WA 4MBBA 4BJOA 3S3HA 5KAAA 1OHDA 2J16B 4ZRTA 1I9TA 2HB1A 4KYRA 2CNFA 3D1OA 2CM7A 1G4WR 2B4SA 1PA1A 3AWGA 5K23A 2QDCA 3RGOA 4OHEA 4GE2A 4RHGA 4GFUA 3BLTA 2F6TA 3ZM0A 1PXHA 2ZMMA 1ZZWA 3A5JA 3I7ZA 2I4GA 2AHSA 2FJMA 4H1OA 4HJPA 5HDEA 2HY3A 2NLKA 3S3FA 3GXHA 1X24A 2H03A 1YTWA 1BZHA 2CMCA 4NYHA 4RDDA 2B4UA 2NT7A 5GTJA 1V3AA 3MOZA 3N0AA 3ZM1A 3V0IA 1PTVA 5K24A 1G7FA 1OESA 4TVVA 1ZC0A 5KACA 1OHEA 1GFYA 2HC1A 3EB1A 2H04A 4YAAA 1LYVA 2F71A 2PA5A 4ZI4A 1G1FA 4D3QA 2I3UA 3D44A 1M3GA 4PVGA 1JLNA 2GP0A 1T48A 2CJZA 3QCJA 3ZMPA 3QCIA 3QCBA 1EEOA 2B49A 1T4JA 2CNEA 3S4EA 3QCMA 2CFVA 1FPZA 1G1HA 3QCKA 3RGQA 4JBCA 1OEUA 2DXPA 5KA8A 2J17A 3EU0A 3V0FA 1C83A 4QBEA 1Q6NA 4DGXA 2HVLA 1LARA 2JJDA 5BUGA 3MMJA 1YTSA 2QCTA 2NV5A 3ZM2A 2QBPA 1L8GA 3D1HA 1YPTA 2QDMA 1C86A 5KA3A 2MBCA 1XXVA 1D5RA 2ZN7A 1NWLA 4I8NA 3I80A 4WU3A 1G1GA 3PS5A 3BM8A 2H4KA 3QCNA 2C7SA 3QCLA 2BGDA 2PQ5A 1Q6TA 5AWXA 4RH9A 4D3PA 5IBMA 1I9SA 1C84A 1JF7A 2CMAA 2Y2FA 1Q6JA 3V0EA 2F6VA 3U96A 4DGPA 2CMBA 1XXPA 4GWFA 5KADA 1PTTA 4D3RA 2VEUA 4QUMA 5K9VA 4WOHA 3QCHA 2I6IA 5KA7A 2PT0A 3QCDA 1MKPA 2I4HA 2IMGA 4QAPA 1QXKA 4JMJA 4QAHA 1GWZA 1BZCA 2VEVA 2M3VA 1BZJA 3O4SA 4RI5A 5K9WA 3A5KA 4AZ1A 1U26A 2I5XA 1NO6A 3O5XA 3H2XA 1C87A 2A3KA 5KA4A 2QCJA 4R30A 2CNGA 1OEMX 1NNYA 3CM3A 3F99A 2VEWA 1L8KA 4RI4A 3SR9A 4ICZA 3OLRA 1ECVA 4R0SA 2CM8A 5KA0A 3D42A 2CNIA 2G59A 2P4DA 4JNBA 5KA2A 2B4PA 1C85A 3EMUA 4NWFA 2B4OA 5KABA 2GJTA 2B3OA 1T49A 1YN9A 3S4OA 2B07A 2H4GA 1OEVA 4J51A 3SMEA 2YDUA 5KA1A 3B7OA 4WTYA 1Q6SA 5KA9A 2BZLA 2J16A 2I4EA 4NWGA 3F41A 3NMEA 5IBSA 3O4TA 3V0DA 1P15A 2C46A 2CM3A 2PI7A 2NTAA 5I6VA 2NT2A 2F46A 2I6MA 3AWFA 2BIJA 1KAKA 3M4UA 2VEYA 1ONZA 3QCCA 3O4UA 1YZ4A 4JMKA 3EZZA 5M43A 4YR8B 1PTYA 1A5YA 2NZ6A 4QUNA 1WRMA 1YWFA 4GRZA 2HNQA 1YTNA 2QBRA 2F6ZA 3GXGA 4OHLA 3RZ2A 2QBQA 3MOWA 4ERCA 1FPRA 4GFVA 2Q47A 4HRFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D1Q A;  4H34 A;  1J4X A;  3BRH A;  2QEP A;  4Y2E A;  1FQ1 A;  2I6J A;  2QDP A;  1ONY A;  3QCF A;  4S0G A;  2GWO A;  3V0J A;  3S3E A;  3EAX A;  1OHC A;  1XM2 A;  1ZCL A;  5J8R A;  2P6X A;  4KYQ A;  1KAV A;  1AAX A;  2R0B A;  5K25 A;  5BZX A;  2PBN A;  1Q1M A;  1XRI A;  3F9B A;  3F81 A;  1NWE A;  2H02 A;  5K22 A;  4WU2 A;  1NL9 A;  2E0T A;  4HJQ A;  2Q05 A;  2I42 A;  4IKC A;  3ZMQ A;  1G7G A;  1RXD A;  4Y14 A;  1Q6P A;  5EHP A;  2HXP A;  2OC3 A;  1LQF A;  4R0T A;  3I36 A;  4NX8 A;  3ZV2 A;  1R6H A;  1OEO X;  1WCH A;  3ZM3 A;  2QBS A;  1EEN A;  1PH0 A;  4GS0 A;  5BZZ A;  1U24 A;  2VEX A;  1I57 A;  1YGU A;  1C88 A;  3S3K A;  4Z6B A;  3QKP A;  2I3R A;  1PTU A;  2AZR A;  2I6P A;  4B04 A;  1YFO A;  3V0H A;  4NND A;  2HC2 A;  2WGP A;  3BLU A;  1QZ0 A;  1Q6M A;  1VHR A;  2A8B A;  2I1Y A;  2PSZ A;  2HNP A;  2OUD A;  2CM2 A;  5LXQ B;  1XBO A;  2RF6 A;  3LJ8 A;  1WAX A;  4GRY A;  4OHI A;  1YGR A;  3AWE A;  3O3L A;  1SUG A;  2FJN A;  4BPC A;  3QCE A;  2G6Z A;  2BV5 A;  3QKQ A;  3V0G A;  1NZ7 A;  2F70 A;  2F6Y A;  3D9C A;  2I75 A;  4KI9 A;  1ZCK A;  4OHD A;  2FH7 A;  5EHR A;  3RO1 A;  1RPM A;  5MMZ B;  2OOQ A;  5BX1 A;  2SHP A;  4QBW A;  2OZ5 A;  4OHH A;  2ESB A;  4ZN5 A;  4RKK A;  2CNH A;  1PYN A;  4RH5 A;  2Y96 A;  2F6F A;  2I6O A;  4PYH A;  1PA9 A;  2HCM A;  1G4U S;  4GE5 A;  2BGE A;  3OMH A;  1U25 A;  3F9A A;  4GE6 A;  2H4V A;  1OET A;  3CWE A;  3QCG A;  2F6W A;  4MBB A;  4BJO A;  3S3H A;  5KAA A;  1OHD A;  2J16 B;  4ZRT A;  1I9T A;  2HB1 A;  4KYR A;  2CNF A;  3D1O A;  2CM7 A;  1G4W R;  2B4S A;  1PA1 A;  3AWG A;  5K23 A;  2QDC A;  3RGO A;  4OHE A;  4GE2 A;  4RHG A;  4GFU A;  3BLT A;  2F6T A;  3ZM0 A;  1PXH A;  2ZMM A;  1ZZW A;  3A5J A;  3I7Z A;  2I4G A;  2AHS A;  2FJM A;  4H1O A;  4HJP A;  5HDE A;  2HY3 A;  2NLK A;  3S3F A;  3GXH A;  1X24 A;  2H03 A;  1YTW A;  1BZH A;  2CMC A;  4NYH A;  4RDD A;  2B4U A;  2NT7 A;  5GTJ A;  1V3A A;  3MOZ A;  3N0A A;  3ZM1 A;  3V0I A;  1PTV A;  5K24 A;  1G7F A;  1OES A;  4TVV A;  1ZC0 A;  5KAC A;  1OHE A;  1GFY A;  2HC1 A;  3EB1 A;  2H04 A;  4YAA A;  1LYV A;  2F71 A;  2PA5 A;  4ZI4 A;  1G1F A;  4D3Q A;  2I3U A;  3D44 A;  1M3G A;  4PVG A;  1JLN A;  2GP0 A;  1T48 A;  2CJZ A;  3QCJ A;  3ZMP A;  3QCI A;  3QCB A;  1EEO A;  2B49 A;  1T4J A;  2CNE A;  3S4E A;  3QCM A;  2CFV A;  1FPZ A;  1G1H A;  3QCK A;  3RGQ A;  4JBC A;  1OEU A;  2DXP A;  5KA8 A;  2J17 A;  3EU0 A;  3V0F A;  1C83 A;  4QBE A;  1Q6N A;  4DGX A;  2HVL A;  1LAR A;  2JJD A;  5BUG A;  3MMJ A;  1YTS A;  2QCT A;  2NV5 A;  3ZM2 A;  2QBP A;  1L8G A;  3D1H A;  1YPT A;  2QDM A;  1C86 A;  5KA3 A;  2MBC A;  1XXV A;  1D5R A;  2ZN7 A;  1NWL A;  4I8N A;  3I80 A;  4WU3 A;  1G1G A;  3PS5 A;  3BM8 A;  2H4K A;  3QCN A;  2C7S A;  3QCL A;  2BGD A;  2PQ5 A;  1Q6T A;  5AWX A;  4RH9 A;  4D3P A;  5IBM A;  1I9S A;  1C84 A;  1JF7 A;  2CMA A;  2Y2F A;  1Q6J A;  3V0E A;  2F6V A;  3U96 A;  4DGP A;  2CMB A;  1XXP A;  4GWF A;  5KAD A;  1PTT A;  4D3R A;  2VEU A;  4QUM A;  5K9V A;  4WOH A;  3QCH A;  2I6I A;  5KA7 A;  2PT0 A;  3QCD A;  1MKP A;  2I4H A;  2IMG A;  4QAP A;  1QXK A;  4JMJ A;  4QAH A;  1GWZ A;  1BZC A;  2VEV A;  2M3V A;  1BZJ A;  3O4S A;  4RI5 A;  5K9W A;  3A5K A;  4AZ1 A;  1U26 A;  2I5X A;  1NO6 A;  3O5X A;  3H2X A;  1C87 A;  2A3K A;  5KA4 A;  2QCJ A;  4R30 A;  2CNG A;  1OEM X;  1NNY A;  3CM3 A;  3F99 A;  2VEW A;  1L8K A;  4RI4 A;  3SR9 A;  4ICZ A;  3OLR A;  1ECV A;  4R0S A;  2CM8 A;  5KA0 A;  3D42 A;  2CNI A;  2G59 A;  2P4D A;  4JNB A;  5KA2 A;  2B4P A;  1C85 A;  3EMU A;  4NWF A;  2B4O A;  5KAB A;  2GJT A;  2B3O A;  1T49 A;  1YN9 A;  3S4O A;  2B07 A;  2H4G A;  1OEV A;  4J51 A;  3SME A;  2YDU A;  5KA1 A;  3B7O A;  4WTY A;  1Q6S A;  5KA9 A;  2BZL A;  2J16 A;  2I4E A;  4NWG A;  3F41 A;  3NME A;  5IBS A;  3O4T A;  3V0D A;  1P15 A;  2C46 A;  2CM3 A;  2PI7 A;  2NTA A;  5I6V A;  2NT2 A;  2F46 A;  2I6M A;  3AWF A;  2BIJ A;  1KAK A;  3M4U A;  2VEY A;  1ONZ A;  3QCC A;  3O4U A;  1YZ4 A;  4JMK A;  3EZZ A;  5M43 A;  4YR8 B;  1PTY A;  1A5Y A;  2NZ6 A;  4QUN A;  1WRM A;  1YWF A;  4GRZ A;  2HNQ A;  1YTN A;  2QBR A;  2F6Z A;  3GXG A;  4OHL A;  3RZ2 A;  2QBQ A;  3MOW A;  4ERC A;  1FPR A;  4GFV A;  2Q47 A;  4HRF A; 
#chains in the Genus database with same CATH topology
 3D1Q A;  2XJA A;  4H34 A;  1J4X A;  3BRH A;  2QEP A;  4Y2E A;  1FQ1 A;  2I6J A;  2QDP A;  1ONY A;  3QCF A;  4S0G A;  1UAG A;  2GWO A;  3V0J A;  3S3E A;  3EAX A;  1OHC A;  1XM2 A;  1ZCL A;  5J8R A;  2P6X A;  3HN7 A;  2WJP A;  4KYQ A;  4BUC A;  1KAV A;  4CVK A;  2JFG A;  1AAX A;  2R0B A;  4QDI A;  5K25 A;  5BZX A;  2PBN A;  1Q1M A;  1XRI A;  2WTZ A;  2F00 A;  3F9B A;  3F81 A;  1NWE A;  2VTD A;  2H02 A;  5K22 A;  4WU2 A;  1NL9 A;  2E0T A;  4HJQ A;  2Q05 A;  2I42 A;  4IKC A;  3ZMQ A;  1G7G A;  1RXD A;  4Y14 A;  1Q6P A;  5EHP A;  2HXP A;  2OC3 A;  1LQF A;  4R0T A;  3I36 A;  4NX8 A;  3ZV2 A;  1R6H A;  1OEO X;  1WCH A;  3ZM3 A;  2QBS A;  1EEN A;  1PH0 A;  4GS0 A;  5BZZ A;  1U24 A;  2VEX A;  1I57 A;  1YGU A;  1C88 A;  3S3K A;  4Z6B A;  3QKP A;  2I3R A;  1PTU A;  2AZR A;  2I6P A;  2UUP A;  3LK7 A;  4B04 A;  1YFO A;  3V0H A;  4NND A;  2HC2 A;  2WGP A;  3BLU A;  1QZ0 A;  4QF5 A;  1Q6M A;  1VHR A;  2A8B A;  2I1Y A;  2PSZ A;  2HNP A;  2OUD A;  2AM2 A;  2CM2 A;  5LXQ B;  1XBO A;  2RF6 A;  3LJ8 A;  1WAX A;  2VTE A;  2XPC A;  4GRY A;  4OHI A;  1YGR A;  3AWE A;  3O3L A;  1SUG A;  2FJN A;  4BPC A;  3QCE A;  2G6Z A;  2BV5 A;  3QKQ A;  3V0G A;  1NZ7 A;  2F70 A;  2F6Y A;  3D9C A;  2I75 A;  4KI9 A;  1ZCK A;  4OHD A;  1JBW A;  2FH7 A;  5EHR A;  2UAG A;  3RO1 A;  2GCB A;  1RPM A;  5MMZ B;  2OOQ A;  5BX1 A;  2SHP A;  4QBW A;  2OZ5 A;  4OHH A;  2ESB A;  4ZN5 A;  4RKK A;  2CNH A;  1PYN A;  4RH5 A;  2Y96 A;  2F6F A;  2I6O A;  4PYH A;  1PA9 A;  2HCM A;  1G4U S;  4GE5 A;  2BGE A;  3OMH A;  1U25 A;  3F9A A;  4GE6 A;  2H4V A;  1OET A;  3CWE A;  3QCG A;  2F6W A;  4MBB A;  4BJO A;  3S3H A;  5KAA A;  1OHD A;  1E8C A;  2J16 B;  4ZRT A;  1I9T A;  1E0D A;  4HV4 A;  2HB1 A;  4KYR A;  2CNF A;  3D1O A;  2CM7 A;  1G4W R;  2B4S A;  1PA1 A;  3AWG A;  5K23 A;  2QDC A;  3RGO A;  2Y67 A;  4GE2 A;  4OHE A;  4RHG A;  4GFU A;  3BLT A;  2F6T A;  3UAG A;  3ZM0 A;  1PXH A;  2ZMM A;  1ZZW A;  3A5J A;  3I7Z A;  4BUB A;  2I4G A;  2AHS A;  2FJM A;  4H1O A;  4HJP A;  5HDE A;  2HY3 A;  2NLK A;  4ZIY A;  3S3F A;  3GXH A;  1X24 A;  2H03 A;  1YTW A;  1BZH A;  2CMC A;  4NYH A;  4RDD A;  2B4U A;  2NT7 A;  5GTJ A;  4CVM A;  1V3A A;  3MOZ A;  3N0A A;  3ZM1 A;  3V0I A;  1PTV A;  5K24 A;  1G7F A;  1OES A;  4TVV A;  1ZC0 A;  5KAC A;  3EB1 A;  1OHE A;  1GFY A;  2HC1 A;  2H04 A;  4YAA A;  1LYV A;  2F71 A;  1W78 A;  4CVL A;  2PA5 A;  2Y1O A;  1GQY A;  2GCA A;  1P31 A;  4ZI4 A;  1G1F A;  4D3Q A;  2I3U A;  3D44 A;  1M3G A;  4PVG A;  1JLN A;  2GP0 A;  1T48 A;  2CJZ A;  3QCJ A;  3ZMP A;  3QCI A;  3QCB A;  1EEO A;  2B49 A;  1T4J A;  2CNE A;  3S4E A;  3QCM A;  2CFV A;  1FPZ A;  1G1H A;  3QCK A;  3RGQ A;  4JBC A;  1OEU A;  2DXP A;  5KA8 A;  1GG4 A;  2J17 A;  2Y68 A;  3EU0 A;  3V0F A;  1JBV A;  1C83 A;  4QBE A;  1Q6N A;  4DGX A;  2HVL A;  1LAR A;  2JJD A;  5BUG A;  3MMJ A;  1YTS A;  2QCT A;  2NV5 A;  3ZM2 A;  2QBP A;  1L8G A;  3D1H A;  1YPT A;  2QDM A;  1C86 A;  5KA3 A;  2MBC A;  1XXV A;  1D5R A;  2ZN7 A;  1NWL A;  4I8N A;  3I80 A;  4WU3 A;  1G1G A;  3N2A A;  3BM8 A;  3PS5 A;  2H4K A;  3QCN A;  2C7S A;  3QCL A;  2BGD A;  2PQ5 A;  1Q6T A;  5AWX A;  4RH9 A;  4UAG A;  4D3P A;  5IBM A;  1I9S A;  1C84 A;  1JF7 A;  2CMA A;  2Y2F A;  1Q6J A;  2VOR A;  3V0E A;  2F6V A;  3U96 A;  4DGP A;  2CMB A;  1XXP A;  4GWF A;  5A5E A;  5KAD A;  1PTT A;  1FGS A;  4D3R A;  2VEU A;  4QUM A;  5K9V A;  4WOH A;  3QCH A;  2I6I A;  5KA7 A;  2PT0 A;  3QCD A;  4C13 A;  2Y66 A;  1MKP A;  2I4H A;  2IMG A;  4QAP A;  1QXK A;  1O5Z A;  2AM1 A;  4JMJ A;  4QAH A;  3ZM6 A;  1GWZ A;  3ZM5 A;  1BZC A;  2VEV A;  2M3V A;  1BZJ A;  2X5O A;  3O4S A;  4RI5 A;  5K9W A;  3A5K A;  4AZ1 A;  1U26 A;  2I5X A;  1NO6 A;  3O5X A;  3H2X A;  1C87 A;  2A3K A;  5KA4 A;  2QCJ A;  2GC6 A;  4R30 A;  2CNG A;  1OEM X;  1NNY A;  3CM3 A;  3F99 A;  2VEW A;  1L8K A;  1W7K A;  4RI4 A;  3SR9 A;  4ICZ A;  3OLR A;  1ECV A;  4R0S A;  2CM8 A;  5KA0 A;  3D42 A;  5A5F A;  2CNI A;  2G59 A;  2P4D A;  4JNB A;  5KA2 A;  2B4P A;  1C85 A;  3EMU A;  4NWF A;  2B4O A;  5KAB A;  4C12 A;  2GJT A;  2B3O A;  1T49 A;  1YN9 A;  3S4O A;  2B07 A;  2H4G A;  1OEV A;  4J51 A;  3SME A;  2YDU A;  5KA1 A;  3NRS A;  3B7O A;  4WTY A;  1Q6S A;  5KA9 A;  2BZL A;  2J16 A;  2I4E A;  4NWG A;  2JFF A;  3QCZ A;  3F41 A;  3NME A;  1GQQ A;  5IBS A;  3PYZ A;  3O4T A;  3V0D A;  1P15 A;  2C46 A;  2CM3 A;  2PI7 A;  2GC5 A;  2VOS A;  2NTA A;  3MVN A;  5I6V A;  2NT2 A;  2F46 A;  2I6M A;  3AWF A;  2BIJ A;  1KAK A;  3M4U A;  2JFH A;  2VEY A;  1ONZ A;  3ZL8 A;  3QCC A;  1J6U A;  3O4U A;  1YZ4 A;  4JMK A;  3EZZ A;  5M43 A;  4YR8 B;  1PTY A;  1A5Y A;  2NZ6 A;  4QUN A;  1EEH A;  1WRM A;  1YWF A;  4GRZ A;  2HNQ A;  1YTN A;  2QBR A;  1P3D A;  2F6Z A;  2UUO A;  3GXG A;  4OHL A;  3RZ2 A;  2QBQ A;  3MOW A;  4ERC A;  1FPR A;  4GFV A;  2Q47 A;  4HRF A; 
#chains in the Genus database with same CATH homology
 3D1Q A;  4H34 A;  1J4X A;  3BRH A;  2QEP A;  4Y2E A;  1FQ1 A;  2I6J A;  2QDP A;  1ONY A;  3QCF A;  4S0G A;  2GWO A;  3V0J A;  3S3E A;  3EAX A;  1OHC A;  1XM2 A;  1ZCL A;  5J8R A;  2P6X A;  4KYQ A;  1KAV A;  1AAX A;  2R0B A;  5K25 A;  5BZX A;  2PBN A;  1Q1M A;  1XRI A;  3F9B A;  3F81 A;  1NWE A;  2H02 A;  5K22 A;  4WU2 A;  1NL9 A;  2E0T A;  4HJQ A;  2Q05 A;  2I42 A;  4IKC A;  3ZMQ A;  1G7G A;  1RXD A;  4Y14 A;  1Q6P A;  5EHP A;  2HXP A;  2OC3 A;  1LQF A;  4R0T A;  3I36 A;  4NX8 A;  3ZV2 A;  1R6H A;  1OEO X;  1WCH A;  3ZM3 A;  2QBS A;  1EEN A;  1PH0 A;  4GS0 A;  5BZZ A;  1U24 A;  2VEX A;  1I57 A;  1YGU A;  1C88 A;  3S3K A;  4Z6B A;  3QKP A;  2I3R A;  1PTU A;  2AZR A;  2I6P A;  4B04 A;  1YFO A;  3V0H A;  4NND A;  2HC2 A;  2WGP A;  3BLU A;  1QZ0 A;  1Q6M A;  1VHR A;  2A8B A;  2I1Y A;  2PSZ A;  2HNP A;  2OUD A;  2CM2 A;  5LXQ B;  1XBO A;  2RF6 A;  3LJ8 A;  1WAX A;  4GRY A;  4OHI A;  1YGR A;  3AWE A;  3O3L A;  1SUG A;  2FJN A;  4BPC A;  3QCE A;  2G6Z A;  2BV5 A;  3QKQ A;  3V0G A;  1NZ7 A;  2F70 A;  2F6Y A;  3D9C A;  2I75 A;  4KI9 A;  1ZCK A;  4OHD A;  2FH7 A;  5EHR A;  3RO1 A;  1RPM A;  5MMZ B;  2OOQ A;  5BX1 A;  2SHP A;  4QBW A;  2OZ5 A;  4OHH A;  2ESB A;  4ZN5 A;  4RKK A;  2CNH A;  1PYN A;  4RH5 A;  2Y96 A;  2F6F A;  2I6O A;  4PYH A;  1PA9 A;  2HCM A;  1G4U S;  4GE5 A;  2BGE A;  3OMH A;  1U25 A;  3F9A A;  4GE6 A;  2H4V A;  1OET A;  3CWE A;  3QCG A;  2F6W A;  4MBB A;  4BJO A;  3S3H A;  5KAA A;  1OHD A;  2J16 B;  4ZRT A;  1I9T A;  2HB1 A;  4KYR A;  2CNF A;  3D1O A;  2CM7 A;  1G4W R;  2B4S A;  1PA1 A;  3AWG A;  5K23 A;  2QDC A;  3RGO A;  4OHE A;  4GE2 A;  4RHG A;  4GFU A;  3BLT A;  2F6T A;  3ZM0 A;  1PXH A;  2ZMM A;  1ZZW A;  3A5J A;  3I7Z A;  2I4G A;  2AHS A;  2FJM A;  4H1O A;  4HJP A;  5HDE A;  2HY3 A;  2NLK A;  3S3F A;  3GXH A;  1X24 A;  2H03 A;  1YTW A;  1BZH A;  2CMC A;  4NYH A;  4RDD A;  2B4U A;  2NT7 A;  5GTJ A;  1V3A A;  3MOZ A;  3N0A A;  3ZM1 A;  3V0I A;  1PTV A;  5K24 A;  1G7F A;  1OES A;  4TVV A;  1ZC0 A;  5KAC A;  1OHE A;  1GFY A;  2HC1 A;  3EB1 A;  2H04 A;  4YAA A;  1LYV A;  2F71 A;  2PA5 A;  4ZI4 A;  1G1F A;  4D3Q A;  2I3U A;  3D44 A;  1M3G A;  4PVG A;  1JLN A;  2GP0 A;  1T48 A;  2CJZ A;  3QCJ A;  3ZMP A;  3QCI A;  3QCB A;  1EEO A;  2B49 A;  1T4J A;  2CNE A;  3S4E A;  3QCM A;  2CFV A;  1FPZ A;  1G1H A;  3QCK A;  3RGQ A;  4JBC A;  1OEU A;  2DXP A;  5KA8 A;  2J17 A;  3EU0 A;  3V0F A;  1C83 A;  4QBE A;  1Q6N A;  4DGX A;  2HVL A;  1LAR A;  2JJD A;  5BUG A;  3MMJ A;  1YTS A;  2QCT A;  2NV5 A;  3ZM2 A;  2QBP A;  1L8G A;  3D1H A;  1YPT A;  2QDM A;  1C86 A;  5KA3 A;  2MBC A;  1XXV A;  1D5R A;  2ZN7 A;  1NWL A;  4I8N A;  3I80 A;  4WU3 A;  1G1G A;  3PS5 A;  3BM8 A;  2H4K A;  3QCN A;  2C7S A;  3QCL A;  2BGD A;  2PQ5 A;  1Q6T A;  5AWX A;  4RH9 A;  4D3P A;  5IBM A;  1I9S A;  1C84 A;  1JF7 A;  2CMA A;  2Y2F A;  1Q6J A;  3V0E A;  2F6V A;  3U96 A;  4DGP A;  2CMB A;  1XXP A;  4GWF A;  5KAD A;  1PTT A;  4D3R A;  2VEU A;  4QUM A;  5K9V A;  4WOH A;  3QCH A;  2I6I A;  5KA7 A;  2PT0 A;  3QCD A;  1MKP A;  2I4H A;  2IMG A;  4QAP A;  1QXK A;  4JMJ A;  4QAH A;  1GWZ A;  1BZC A;  2VEV A;  2M3V A;  1BZJ A;  3O4S A;  4RI5 A;  5K9W A;  3A5K A;  4AZ1 A;  1U26 A;  2I5X A;  1NO6 A;  3O5X A;  3H2X A;  1C87 A;  2A3K A;  5KA4 A;  2QCJ A;  4R30 A;  2CNG A;  1OEM X;  1NNY A;  3CM3 A;  3F99 A;  2VEW A;  1L8K A;  4RI4 A;  3SR9 A;  4ICZ A;  3OLR A;  1ECV A;  4R0S A;  2CM8 A;  5KA0 A;  3D42 A;  2CNI A;  2G59 A;  2P4D A;  4JNB A;  5KA2 A;  2B4P A;  1C85 A;  3EMU A;  4NWF A;  2B4O A;  5KAB A;  2GJT A;  2B3O A;  1T49 A;  1YN9 A;  3S4O A;  2B07 A;  2H4G A;  1OEV A;  4J51 A;  3SME A;  2YDU A;  5KA1 A;  3B7O A;  4WTY A;  1Q6S A;  5KA9 A;  2BZL A;  2J16 A;  2I4E A;  4NWG A;  3F41 A;  3NME A;  5IBS A;  3O4T A;  3V0D A;  1P15 A;  2C46 A;  2CM3 A;  2PI7 A;  2NTA A;  5I6V A;  2NT2 A;  2F46 A;  2I6M A;  3AWF A;  2BIJ A;  1KAK A;  3M4U A;  2VEY A;  1ONZ A;  3QCC A;  3O4U A;  1YZ4 A;  4JMK A;  3EZZ A;  5M43 A;  4YR8 B;  1PTY A;  1A5Y A;  2NZ6 A;  4QUN A;  1WRM A;  1YWF A;  4GRZ A;  2HNQ A;  1YTN A;  2QBR A;  2F6Z A;  3GXG A;  4OHL A;  3RZ2 A;  2QBQ A;  3MOW A;  4ERC A;  1FPR A;  4GFV A;  2Q47 A;  4HRF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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