4GRYA

Crystal structure of shp1 catalytic domain with so4
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
283
structure length
271
Chain Sequence
GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLNAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 6
total genus 91
structure length 271
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2012-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4gryA00
1NL9A 4R30A 1BZHA 1XM2A 2CNGA 5KA1A 1ZC0A 4RI4A 1ZCKA 3BLUA 3D42A 1C83A 3QCNA 2CNFA 2HC2A 4S0GA 1P15A 3QKQA 2I1YA 3CWEA 3H2XA 2QDPA 1RXDA 2FJMA 4QBWA 2H4KA 4BPCA 2OZ5A 2G59A 2BZLA 1PA9A 1Q1MA 4RI5A 2CMCA 1A5YA 3F41A 3RZ2A 4NWFA 1OEVA 2H03A 5IBMA 1G1HA 2NT2A 3QCIA 2VEYA 1L8GA 3I36A 1YN9A 3AWEA 2B07A 1C84A 1C87A 1T4JA 2QCJA 3ZMPA 1M3GA 4RKKA 5KA2A 2CM8A 3SMEA 2WGPA 5LXQB 2YDUA 4QUMA 2B4SA 4GRZA 4ERCA 4Z6BA 2H4GA 4NX8A 5MMZB 1YTSA 2OC3A 2NLKA 2I75A 2I4GA 2NV5A 2CNHA 4JBCA 2HB1A 3EZZA 2P6XA 4RDDA 1OEUA 5KA3A 1YGRA 4ICZA 1U24A 1G1FA 4ZN5A 1Q6PA 2I6PA 1D5RA 4MBBA 2B4PA 2HNQA 1WAXA 5EHPA 3ZM0A 3ZM3A 2IMGA 2C7SA 2H02A 3O3LA 5BZXA 2HXPA 1EEOA 5HDEA 5KA9A 2F70A 3EU0A 1KAVA 2F6YA 5KA4A 5K25A 2QDMA 4PVGA 3AWFA 1XRIA 1ZZWA 2J16A 1V3AA 2J17A 5KABA 3GXGA 4QAHA 3A5JA 2RF6A 1QZ0A 2QDCA 4D3RA 2I6IA 3QCJA 3OLRA 4GRYA 1YTNA 2M3VA 1C86A 2SHPA 1C85A 1FPRA 3I7ZA 1GFYA 1NWEA 3U96A 2QCTA 2I42A 3V0HA 1XBOA 2I5XA 4HJPA 3OMHA 2Q47A 4RH5A 1T49A 2PA5A 1YWFA 3M4UA 2HC1A 5KADA 2AZRA 4JMKA 2VEWA 3BM8A 1JF7A 2CMAA 3BLTA 3F99A 3O4SA 2GP0A 1YTWA 3V0JA 5K23A 2A8BA 4BJOA 5AWXA 4GFUA 5KA7A 1Q6JA 4I8NA 2HNPA 2H4VA 3RGOA 2H04A 2HY3A 1ONZA 4OHHA 5KA8A 4J51A 4Y14A 1MKPA 2CM2A 4DGPA 2F6TA 3NMEA 2ZN7A 1XXPA 3S3HA 1PYNA 2PT0A 4JMJA 2C46A 2B4UA 2R0BA 3RGQA 1G1GA 1YGUA 2ZMMA 2QBRA 3B7OA 4OHEA 4KYRA 1YZ4A 5K9VA 3D1OA 3QCLA 2PSZA 4RHGA 2VEXA 3D44A 2NZ6A 3BRHA 1G4US 2I4HA 1ZCLA 2BV5A 3EMUA 1OHEA 3V0FA 2A3KA 5BZZA 2F6FA 3S4EA 2GWOA 4GE5A 3N0AA 2FH7A 4GE6A 1LARA 3O4TA 2Y96A 4QUNA 4HRFA 1NNYA 3D1HA 1G7GA 4ZRTA 1NO6A 2PBNA 1WRMA 3V0IA 3QCEA 4OHDA 4OHLA 3O4UA 1SUGA 3MOZA 2GJTA 5KAAA 1NZ7A 2B49A 3ZMQA 1Q6SA 1WCHA 2QBSA 1PTTA 1T48A 1GWZA 1NWLA 2AHSA 2G6ZA 4KI9A 1J4XA 5J8RA 1FPZA 1VHRA 3V0EA 1OHDA 2F6WA 2I6MA 1OESA 2QBQA 3F9AA 2CNEA 2P4DA 1ECVA 5K9WA 5KACA 2F6ZA 4R0SA 2CFVA 5EHRA 1I57A 2CM3A 4JNBA 3MOWA 4GE2A 4OHIA 2HVLA 4TVVA 4GFVA 3D9CA 2BIJA 1PH0A 3QCBA 3QCDA 3S4OA 5GTJA 3ZM1A 4Y2EA 3EAXA 2PQ5A 1PXHA 3S3EA 4PYHA 4QBEA 4NNDA 2BGEA 5BUGA 4HJQA 5M43A 1U25A 2CJZA 1BZCA 1JLNA 2CM7A 2Y2FA 4ZI4A 1LYVA 3QCCA 2JJDA 3F81A 1PTVA 4YR8B 3LJ8A 3AWGA 2QEPA 2B4OA 3A5KA 3F9BA 4WTYA 4H1OA 3PS5A 1Q6TA 1U26A 1G7FA 1QXKA 4GWFA 3S3FA 1X24A 4NYHA 3O5XA 2VEVA 1I9SA 2OUDA 2I3RA 3ZV2A 1Q6MA 4R0TA 2HCMA 1BZJA 4DGXA 4AZ1A 3QKPA 4WU2A 3QCFA 4B04A 4WU3A 2VEUA 3D1QA 3RO1A 2E0TA 2PI7A 3ZM2A 1PTYA 2F46A 2DXPA 1EENA 1RPMA 5IBSA 1OETA 2QBPA 1LQFA 1R6HA 1KAKA 3MMJA 2J16B 3GXHA 4WOHA 1Q6NA 4H34A 1XXVA 2F6VA 3V0GA 2OOQA 1G4WR 3QCHA 1OEMX 2I3UA 3QCMA 4QAPA 2NTAA 2I4EA 1YPTA 2CNIA 3SR9A 2NT7A 4YAAA 5BX1A 3S3KA 4RH9A 3V0DA 4GS0A 2I6OA 4D3QA 3EB1A 4NWGA 1C88A 2ESBA 4IKCA 5K24A 2Q05A 3QCGA 1I9TA 2FJNA 1OHCA 4KYQA 5KA0A 5I6VA 3QCKA 1PTUA 2CMBA 1ONYA 1PA1A 1YFOA 1FQ1A 3I80A 2B3OA 5K22A 3CM3A 2BGDA 2F71A 2I6JA 1OEOX 1L8KA 1AAXA 4D3PA 2MBCA
chains in the Genus database with same CATH superfamily
1NL9A 4R30A 1BZHA 1XM2A 2CNGA 1W78A 1GG4A 5KA1A 1ZC0A 4RI4A 1ZCKA 3BLUA 3D42A 1O5ZA 1C83A 3QCNA 2CNFA 2HC2A 4S0GA 1P15A 3QKQA 4HV4A 2I1YA 3CWEA 3UAGA 2GC6A 3H2XA 4CVKA 2QDPA 1RXDA 2FJMA 4QBWA 2H4KA 4BPCA 2AM2A 2OZ5A 3PYZA 2G59A 2BZLA 2WTZA 1PA9A 1Q1MA 4RI5A 2CMCA 1A5YA 3F41A 3RZ2A 4NWFA 1OEVA 2H03A 5IBMA 1G1HA 2NT2A 1E0DA 1JBWA 5A5EA 3QCIA 2VEYA 2VTEA 1L8GA 3I36A 1YN9A 3AWEA 2B07A 1C84A 1C87A 1T4JA 2QCJA 3ZMPA 4QF5A 1M3GA 4RKKA 5KA2A 2CM8A 3SMEA 2WGPA 5LXQB 2YDUA 4QUMA 2B4SA 4GRZA 4ERCA 4Z6BA 2H4GA 4NX8A 5MMZB 1YTSA 2OC3A 2XJAA 2NLKA 2I75A 2I4GA 2NV5A 2CNHA 4JBCA 2HB1A 1J6UA 3EZZA 2P6XA 4RDDA 1OEUA 5KA3A 1YGRA 4ICZA 1U24A 1G1FA 4QDIA 4ZN5A 1Q6PA 2I6PA 1D5RA 4MBBA 2B4PA 2HNQA 1WAXA 5EHPA 3ZM0A 3ZM3A 4ZIYA 2IMGA 2C7SA 2H02A 3O3LA 5BZXA 2HXPA 1EEOA 5HDEA 1P31A 3QCZA 5KA9A 4C13A 2F70A 3EU0A 1KAVA 2F6YA 5KA4A 2Y66A 5K25A 2QDMA 4PVGA 3AWFA 1XRIA 1ZZWA 2J16A 1V3AA 2GCBA 2J17A 4CVMA 5KABA 3GXGA 4QAHA 3A5JA 2RF6A 1QZ0A 2QDCA 4D3RA 2I6IA 3NRSA 3OLRA 3QCJA 4GRYA 3ZM6A 2Y67A 1YTNA 2M3VA 1C86A 2SHPA 1C85A 1FPRA 3I7ZA 1GFYA 1NWEA 1P3DA 3U96A 4BUCA 2QCTA 2F00A 2I42A 3V0HA 1XBOA 2I5XA 4HJPA 3OMHA 2Q47A 4RH5A 1T49A 2UUOA 2PA5A 1YWFA 3M4UA 2HC1A 2X5OA 3HN7A 5KADA 2AZRA 4JMKA 2VEWA 3BM8A 1JF7A 2CMAA 3BLTA 3F99A 3O4SA 2GP0A 1YTWA 3V0JA 5K23A 2A8BA 4BJOA 5AWXA 1W7KA 2XPCA 4GFUA 5KA7A 1Q6JA 2Y1OA 2WJPA 4I8NA 2HNPA 2H4VA 3RGOA 2H04A 2HY3A 1ONZA 4OHHA 5KA8A 1UAGA 4J51A 4Y14A 1MKPA 2CM2A 4DGPA 2F6TA 3NMEA 2ZN7A 1XXPA 3S3HA 1PYNA 2PT0A 4JMJA 2C46A 2B4UA 2R0BA 1E8CA 3RGQA 1G1GA 1YGUA 2ZMMA 2QBRA 3B7OA 4OHEA 4KYRA 1YZ4A 5K9VA 3D1OA 3QCLA 2PSZA 4RHGA 2VEXA 3ZL8A 3D44A 2NZ6A 3BRHA 1G4US 2I4HA 1ZCLA 2BV5A 3EMUA 1OHEA 3V0FA 2A3KA 5BZZA 2F6FA 3S4EA 2GWOA 4GE5A 3N0AA 2FH7A 4GE6A 4BUBA 1LARA 3O4TA 2Y96A 4QUNA 4HRFA 1NNYA 3D1HA 1G7GA 4ZRTA 1NO6A 2PBNA 1WRMA 3V0IA 2GC5A 1JBVA 2VOSA 3QCEA 4OHDA 4OHLA 3O4UA 1SUGA 3MOZA 2GJTA 5KAAA 1NZ7A 2B49A 3ZMQA 1Q6SA 1WCHA 2AM1A 2QBSA 1PTTA 1T48A 1GWZA 1NWLA 2AHSA 2G6ZA 4KI9A 1J4XA 5J8RA 1FPZA 1VHRA 3V0EA 1OHDA 2F6WA 2I6MA 2JFFA 1OESA 2QBQA 3F9AA 2CNEA 2P4DA 1ECVA 5K9WA 5KACA 2F6ZA 4R0SA 3MVNA 2CFVA 5EHRA 1I57A 2CM3A 4JNBA 3MOWA 3ZM5A 4GE2A 4OHIA 2HVLA 3N2AA 4TVVA 4GFVA 3D9CA 2BIJA 1PH0A 3QCBA 3QCDA 3S4OA 5GTJA 3ZM1A 4Y2EA 3EAXA 2PQ5A 1PXHA 3S3EA 4PYHA 4QBEA 4NNDA 2BGEA 5BUGA 4HJQA 2JFGA 5M43A 1U25A 2CJZA 1BZCA 2VORA 1JLNA 2CM7A 2Y2FA 4ZI4A 4UAGA 1LYVA 3QCCA 2JJDA 3F81A 1PTVA 4YR8B 1GQQA 3LJ8A 3AWGA 2QEPA 2B4OA 3A5KA 3F9BA 4WTYA 4H1OA 3PS5A 1Q6TA 1U26A 1G7FA 1QXKA 4GWFA 3S3FA 1X24A 4NYHA 3O5XA 2VEVA 1I9SA 2OUDA 2I3RA 3ZV2A 1Q6MA 4R0TA 2HCMA 1BZJA 4DGXA 4AZ1A 2JFHA 3QKPA 4WU2A 3QCFA 4B04A 4WU3A 2VEUA 3D1QA 3RO1A 2E0TA 2PI7A 3ZM2A 1PTYA 2F46A 2DXPA 1EENA 1RPMA 5IBSA 1OETA 2QBPA 1LQFA 1R6HA 1KAKA 3MMJA 2J16B 3GXHA 2UUPA 4WOHA 1EEHA 1Q6NA 4H34A 1XXVA 1FGSA 2F6VA 3V0GA 2OOQA 1G4WR 3QCHA 1OEMX 2I3UA 2Y68A 3QCMA 4QAPA 2NTAA 2I4EA 1YPTA 2CNIA 3SR9A 2UAGA 2NT7A 4YAAA 5BX1A 3S3KA 4RH9A 3V0DA 4GS0A 2I6OA 4D3QA 3EB1A 5A5FA 4NWGA 1C88A 2ESBA 4IKCA 5K24A 2VTDA 4C12A 2Q05A 3QCGA 1I9TA 2FJNA 1OHCA 4KYQA 1GQYA 5KA0A 5I6VA 3QCKA 1PTUA 2CMBA 1ONYA 1PA1A 3LK7A 1YFOA 1FQ1A 3I80A 2B3OA 5K22A 3CM3A 2BGDA 2GCAA 2F71A 2I6JA 1OEOX 4CVLA 1L8KA 1AAXA 4D3PA 2MBCA
chains in the Genus database with same CATH topology
1NL9A 4R30A 1BZHA 1XM2A 2CNGA 5KA1A 1ZC0A 4RI4A 1ZCKA 3BLUA 3D42A 1C83A 3QCNA 2CNFA 2HC2A 4S0GA 1P15A 3QKQA 2I1YA 3CWEA 3H2XA 2QDPA 1RXDA 2FJMA 4QBWA 2H4KA 4BPCA 2OZ5A 2G59A 2BZLA 1PA9A 1Q1MA 4RI5A 2CMCA 1A5YA 3F41A 3RZ2A 4NWFA 1OEVA 2H03A 5IBMA 1G1HA 2NT2A 3QCIA 2VEYA 1L8GA 3I36A 1YN9A 3AWEA 2B07A 1C84A 1C87A 1T4JA 2QCJA 3ZMPA 1M3GA 4RKKA 5KA2A 2CM8A 3SMEA 2WGPA 5LXQB 2YDUA 4QUMA 2B4SA 4GRZA 4ERCA 4Z6BA 2H4GA 4NX8A 5MMZB 1YTSA 2OC3A 2NLKA 2I75A 2I4GA 2NV5A 2CNHA 4JBCA 2HB1A 3EZZA 2P6XA 4RDDA 1OEUA 5KA3A 1YGRA 4ICZA 1U24A 1G1FA 4ZN5A 1Q6PA 2I6PA 1D5RA 4MBBA 2B4PA 2HNQA 1WAXA 5EHPA 3ZM0A 3ZM3A 2IMGA 2C7SA 2H02A 3O3LA 5BZXA 2HXPA 1EEOA 5HDEA 5KA9A 2F70A 3EU0A 1KAVA 2F6YA 5KA4A 5K25A 2QDMA 4PVGA 3AWFA 1XRIA 1ZZWA 2J16A 1V3AA 2J17A 5KABA 3GXGA 4QAHA 3A5JA 2RF6A 1QZ0A 2QDCA 4D3RA 2I6IA 3QCJA 3OLRA 4GRYA 1YTNA 2M3VA 1C86A 2SHPA 1C85A 1FPRA 3I7ZA 1GFYA 1NWEA 3U96A 2QCTA 2I42A 3V0HA 1XBOA 2I5XA 4HJPA 3OMHA 2Q47A 4RH5A 1T49A 2PA5A 1YWFA 3M4UA 2HC1A 5KADA 2AZRA 4JMKA 2VEWA 3BM8A 1JF7A 2CMAA 3BLTA 3F99A 3O4SA 2GP0A 1YTWA 3V0JA 5K23A 2A8BA 4BJOA 5AWXA 4GFUA 5KA7A 1Q6JA 4I8NA 2HNPA 2H4VA 3RGOA 2H04A 2HY3A 1ONZA 4OHHA 5KA8A 4J51A 4Y14A 1MKPA 2CM2A 4DGPA 2F6TA 3NMEA 2ZN7A 1XXPA 3S3HA 1PYNA 2PT0A 4JMJA 2C46A 2B4UA 2R0BA 3RGQA 1G1GA 1YGUA 2ZMMA 2QBRA 3B7OA 4OHEA 4KYRA 1YZ4A 5K9VA 3D1OA 3QCLA 2PSZA 4RHGA 2VEXA 3D44A 2NZ6A 3BRHA 1G4US 2I4HA 1ZCLA 2BV5A 3EMUA 1OHEA 3V0FA 2A3KA 5BZZA 2F6FA 3S4EA 2GWOA 4GE5A 3N0AA 2FH7A 4GE6A 1LARA 3O4TA 2Y96A 4QUNA 4HRFA 1NNYA 3D1HA 1G7GA 4ZRTA 1NO6A 2PBNA 1WRMA 3V0IA 3QCEA 4OHDA 4OHLA 3O4UA 1SUGA 3MOZA 2GJTA 5KAAA 1NZ7A 2B49A 3ZMQA 1Q6SA 1WCHA 2QBSA 1PTTA 1T48A 1GWZA 1NWLA 2AHSA 2G6ZA 4KI9A 1J4XA 5J8RA 1FPZA 1VHRA 3V0EA 1OHDA 2F6WA 2I6MA 1OESA 2QBQA 3F9AA 2CNEA 2P4DA 1ECVA 5K9WA 5KACA 2F6ZA 4R0SA 2CFVA 5EHRA 1I57A 2CM3A 4JNBA 3MOWA 4GE2A 4OHIA 2HVLA 4TVVA 4GFVA 3D9CA 2BIJA 1PH0A 3QCBA 3QCDA 3S4OA 5GTJA 3ZM1A 4Y2EA 3EAXA 2PQ5A 1PXHA 3S3EA 4PYHA 4QBEA 4NNDA 2BGEA 5BUGA 4HJQA 5M43A 1U25A 2CJZA 1BZCA 1JLNA 2CM7A 2Y2FA 4ZI4A 1LYVA 3QCCA 2JJDA 3F81A 1PTVA 4YR8B 3LJ8A 3AWGA 2QEPA 2B4OA 3A5KA 3F9BA 4WTYA 4H1OA 3PS5A 1Q6TA 1U26A 1G7FA 1QXKA 4GWFA 3S3FA 1X24A 4NYHA 3O5XA 2VEVA 1I9SA 2OUDA 2I3RA 3ZV2A 1Q6MA 4R0TA 2HCMA 1BZJA 4DGXA 4AZ1A 3QKPA 4WU2A 3QCFA 4B04A 4WU3A 2VEUA 3D1QA 3RO1A 2E0TA 2PI7A 3ZM2A 1PTYA 2F46A 2DXPA 1EENA 1RPMA 5IBSA 1OETA 2QBPA 1LQFA 1R6HA 1KAKA 3MMJA 2J16B 3GXHA 4WOHA 1Q6NA 4H34A 1XXVA 2F6VA 3V0GA 2OOQA 1G4WR 3QCHA 1OEMX 2I3UA 3QCMA 4QAPA 2NTAA 2I4EA 1YPTA 2CNIA 3SR9A 2NT7A 4YAAA 5BX1A 3S3KA 4RH9A 3V0DA 4GS0A 2I6OA 4D3QA 3EB1A 4NWGA 1C88A 2ESBA 4IKCA 5K24A 2Q05A 3QCGA 1I9TA 2FJNA 1OHCA 4KYQA 5KA0A 5I6VA 3QCKA 1PTUA 2CMBA 1ONYA 1PA1A 1YFOA 1FQ1A 3I80A 2B3OA 5K22A 3CM3A 2BGDA 2F71A 2I6JA 1OEOX 1L8KA 1AAXA 4D3PA 2MBCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NL9 A;  4R30 A;  1BZH A;  1XM2 A;  2CNG A;  5KA1 A;  1ZC0 A;  4RI4 A;  1ZCK A;  3BLU A;  3D42 A;  1C83 A;  3QCN A;  2CNF A;  2HC2 A;  4S0G A;  1P15 A;  3QKQ A;  2I1Y A;  3CWE A;  3H2X A;  2QDP A;  1RXD A;  2FJM A;  4QBW A;  2H4K A;  4BPC A;  2OZ5 A;  2G59 A;  2BZL A;  1PA9 A;  1Q1M A;  4RI5 A;  2CMC A;  1A5Y A;  3F41 A;  3RZ2 A;  4NWF A;  1OEV A;  2H03 A;  5IBM A;  1G1H A;  2NT2 A;  3QCI A;  2VEY A;  1L8G A;  3I36 A;  1YN9 A;  3AWE A;  2B07 A;  1C84 A;  1C87 A;  1T4J A;  2QCJ A;  3ZMP A;  1M3G A;  4RKK A;  5KA2 A;  2CM8 A;  3SME A;  2WGP A;  5LXQ B;  2YDU A;  4QUM A;  2B4S A;  4GRZ A;  4ERC A;  4Z6B A;  2H4G A;  4NX8 A;  5MMZ B;  1YTS A;  2OC3 A;  2NLK A;  2I75 A;  2I4G A;  2NV5 A;  2CNH A;  4JBC A;  2HB1 A;  3EZZ A;  2P6X A;  4RDD A;  1OEU A;  5KA3 A;  1YGR A;  4ICZ A;  1U24 A;  1G1F A;  4ZN5 A;  1Q6P A;  2I6P A;  1D5R A;  4MBB A;  2B4P A;  2HNQ A;  1WAX A;  5EHP A;  3ZM0 A;  3ZM3 A;  2IMG A;  2C7S A;  2H02 A;  3O3L A;  5BZX A;  2HXP A;  1EEO A;  5HDE A;  5KA9 A;  2F70 A;  3EU0 A;  1KAV A;  2F6Y A;  5KA4 A;  5K25 A;  2QDM A;  4PVG A;  3AWF A;  1XRI A;  1ZZW A;  2J16 A;  1V3A A;  2J17 A;  5KAB A;  3GXG A;  4QAH A;  3A5J A;  2RF6 A;  1QZ0 A;  2QDC A;  4D3R A;  2I6I A;  3QCJ A;  3OLR A;  4GRY A;  1YTN A;  2M3V A;  1C86 A;  2SHP A;  1C85 A;  1FPR A;  3I7Z A;  1GFY A;  1NWE A;  3U96 A;  2QCT A;  2I42 A;  3V0H A;  1XBO A;  2I5X A;  4HJP A;  3OMH A;  2Q47 A;  4RH5 A;  1T49 A;  2PA5 A;  1YWF A;  3M4U A;  2HC1 A;  5KAD A;  2AZR A;  4JMK A;  2VEW A;  3BM8 A;  1JF7 A;  2CMA A;  3BLT A;  3F99 A;  3O4S A;  2GP0 A;  1YTW A;  3V0J A;  5K23 A;  2A8B A;  4BJO A;  5AWX A;  4GFU A;  5KA7 A;  1Q6J A;  4I8N A;  2HNP A;  2H4V A;  3RGO A;  2H04 A;  2HY3 A;  1ONZ A;  4OHH A;  5KA8 A;  4J51 A;  4Y14 A;  1MKP A;  2CM2 A;  4DGP A;  2F6T A;  3NME A;  2ZN7 A;  1XXP A;  3S3H A;  1PYN A;  2PT0 A;  4JMJ A;  2C46 A;  2B4U A;  2R0B A;  3RGQ A;  1G1G A;  1YGU A;  2ZMM A;  2QBR A;  3B7O A;  4OHE A;  4KYR A;  1YZ4 A;  5K9V A;  3D1O A;  3QCL A;  2PSZ A;  4RHG A;  2VEX A;  3D44 A;  2NZ6 A;  3BRH A;  1G4U S;  2I4H A;  1ZCL A;  2BV5 A;  3EMU A;  1OHE A;  3V0F A;  2A3K A;  5BZZ A;  2F6F A;  3S4E A;  2GWO A;  4GE5 A;  3N0A A;  2FH7 A;  4GE6 A;  1LAR A;  3O4T A;  2Y96 A;  4QUN A;  4HRF A;  1NNY A;  3D1H A;  1G7G A;  4ZRT A;  1NO6 A;  2PBN A;  1WRM A;  3V0I A;  3QCE A;  4OHD A;  4OHL A;  3O4U A;  1SUG A;  3MOZ A;  2GJT A;  5KAA A;  1NZ7 A;  2B49 A;  3ZMQ A;  1Q6S A;  1WCH A;  2QBS A;  1PTT A;  1T48 A;  1GWZ A;  1NWL A;  2AHS A;  2G6Z A;  4KI9 A;  1J4X A;  5J8R A;  1FPZ A;  1VHR A;  3V0E A;  1OHD A;  2F6W A;  2I6M A;  1OES A;  2QBQ A;  3F9A A;  2CNE A;  2P4D A;  1ECV A;  5K9W A;  5KAC A;  2F6Z A;  4R0S A;  2CFV A;  5EHR A;  1I57 A;  2CM3 A;  4JNB A;  3MOW A;  4GE2 A;  4OHI A;  2HVL A;  4TVV A;  4GFV A;  3D9C A;  2BIJ A;  1PH0 A;  3QCB A;  3QCD A;  3S4O A;  5GTJ A;  3ZM1 A;  4Y2E A;  3EAX A;  2PQ5 A;  1PXH A;  3S3E A;  4PYH A;  4QBE A;  4NND A;  2BGE A;  5BUG A;  4HJQ A;  5M43 A;  1U25 A;  2CJZ A;  1BZC A;  1JLN A;  2CM7 A;  2Y2F A;  4ZI4 A;  1LYV A;  3QCC A;  2JJD A;  3F81 A;  1PTV A;  4YR8 B;  3LJ8 A;  3AWG A;  2QEP A;  2B4O A;  3A5K A;  3F9B A;  4WTY A;  4H1O A;  3PS5 A;  1Q6T A;  1U26 A;  1G7F A;  1QXK A;  4GWF A;  3S3F A;  1X24 A;  4NYH A;  3O5X A;  2VEV A;  1I9S A;  2OUD A;  2I3R A;  3ZV2 A;  1Q6M A;  4R0T A;  2HCM A;  1BZJ A;  4DGX A;  4AZ1 A;  3QKP A;  4WU2 A;  3QCF A;  4B04 A;  4WU3 A;  2VEU A;  3D1Q A;  3RO1 A;  2E0T A;  2PI7 A;  3ZM2 A;  1PTY A;  2F46 A;  2DXP A;  1EEN A;  1RPM A;  5IBS A;  1OET A;  2QBP A;  1LQF A;  1R6H A;  1KAK A;  3MMJ A;  2J16 B;  3GXH A;  4WOH A;  1Q6N A;  4H34 A;  1XXV A;  2F6V A;  3V0G A;  2OOQ A;  1G4W R;  3QCH A;  1OEM X;  2I3U A;  3QCM A;  4QAP A;  2NTA A;  2I4E A;  1YPT A;  2CNI A;  3SR9 A;  2NT7 A;  4YAA A;  5BX1 A;  3S3K A;  4RH9 A;  3V0D A;  4GS0 A;  2I6O A;  4D3Q A;  3EB1 A;  4NWG A;  1C88 A;  2ESB A;  4IKC A;  5K24 A;  2Q05 A;  3QCG A;  1I9T A;  2FJN A;  1OHC A;  4KYQ A;  5KA0 A;  5I6V A;  3QCK A;  1PTU A;  2CMB A;  1ONY A;  1PA1 A;  1YFO A;  1FQ1 A;  3I80 A;  2B3O A;  5K22 A;  3CM3 A;  2BGD A;  2F71 A;  2I6J A;  1OEO X;  1L8K A;  1AAX A;  4D3P A;  2MBC A; 
#chains in the Genus database with same CATH topology
 1NL9 A;  4R30 A;  1BZH A;  1XM2 A;  2CNG A;  1W78 A;  1GG4 A;  5KA1 A;  1ZC0 A;  4RI4 A;  1ZCK A;  3BLU A;  3D42 A;  1O5Z A;  1C83 A;  3QCN A;  2CNF A;  2HC2 A;  4S0G A;  1P15 A;  3QKQ A;  4HV4 A;  2I1Y A;  3CWE A;  3UAG A;  2GC6 A;  3H2X A;  4CVK A;  2QDP A;  1RXD A;  2FJM A;  4QBW A;  2H4K A;  4BPC A;  2AM2 A;  2OZ5 A;  3PYZ A;  2G59 A;  2BZL A;  2WTZ A;  1PA9 A;  1Q1M A;  4RI5 A;  2CMC A;  1A5Y A;  3F41 A;  3RZ2 A;  4NWF A;  1OEV A;  2H03 A;  5IBM A;  1G1H A;  2NT2 A;  1E0D A;  1JBW A;  5A5E A;  3QCI A;  2VEY A;  2VTE A;  1L8G A;  3I36 A;  1YN9 A;  3AWE A;  2B07 A;  1C84 A;  1C87 A;  1T4J A;  2QCJ A;  3ZMP A;  4QF5 A;  1M3G A;  4RKK A;  5KA2 A;  2CM8 A;  3SME A;  2WGP A;  5LXQ B;  2YDU A;  4QUM A;  2B4S A;  4GRZ A;  4ERC A;  4Z6B A;  2H4G A;  4NX8 A;  5MMZ B;  1YTS A;  2OC3 A;  2XJA A;  2NLK A;  2I75 A;  2I4G A;  2NV5 A;  2CNH A;  4JBC A;  2HB1 A;  1J6U A;  3EZZ A;  2P6X A;  4RDD A;  1OEU A;  5KA3 A;  1YGR A;  4ICZ A;  1U24 A;  1G1F A;  4QDI A;  4ZN5 A;  1Q6P A;  2I6P A;  1D5R A;  4MBB A;  2B4P A;  2HNQ A;  1WAX A;  5EHP A;  3ZM0 A;  3ZM3 A;  4ZIY A;  2IMG A;  2C7S A;  2H02 A;  3O3L A;  5BZX A;  2HXP A;  1EEO A;  5HDE A;  1P31 A;  3QCZ A;  5KA9 A;  4C13 A;  2F70 A;  3EU0 A;  1KAV A;  2F6Y A;  5KA4 A;  2Y66 A;  5K25 A;  2QDM A;  4PVG A;  3AWF A;  1XRI A;  1ZZW A;  2J16 A;  1V3A A;  2GCB A;  2J17 A;  4CVM A;  5KAB A;  3GXG A;  4QAH A;  3A5J A;  2RF6 A;  1QZ0 A;  2QDC A;  4D3R A;  2I6I A;  3NRS A;  3OLR A;  3QCJ A;  4GRY A;  3ZM6 A;  2Y67 A;  1YTN A;  2M3V A;  1C86 A;  2SHP A;  1C85 A;  1FPR A;  3I7Z A;  1GFY A;  1NWE A;  1P3D A;  3U96 A;  4BUC A;  2QCT A;  2F00 A;  2I42 A;  3V0H A;  1XBO A;  2I5X A;  4HJP A;  3OMH A;  2Q47 A;  4RH5 A;  1T49 A;  2UUO A;  2PA5 A;  1YWF A;  3M4U A;  2HC1 A;  2X5O A;  3HN7 A;  5KAD A;  2AZR A;  4JMK A;  2VEW A;  3BM8 A;  1JF7 A;  2CMA A;  3BLT A;  3F99 A;  3O4S A;  2GP0 A;  1YTW A;  3V0J A;  5K23 A;  2A8B A;  4BJO A;  5AWX A;  1W7K A;  2XPC A;  4GFU A;  5KA7 A;  1Q6J A;  2Y1O A;  2WJP A;  4I8N A;  2HNP A;  2H4V A;  3RGO A;  2H04 A;  2HY3 A;  1ONZ A;  4OHH A;  5KA8 A;  1UAG A;  4J51 A;  4Y14 A;  1MKP A;  2CM2 A;  4DGP A;  2F6T A;  3NME A;  2ZN7 A;  1XXP A;  3S3H A;  1PYN A;  2PT0 A;  4JMJ A;  2C46 A;  2B4U A;  2R0B A;  1E8C A;  3RGQ A;  1G1G A;  1YGU A;  2ZMM A;  2QBR A;  3B7O A;  4OHE A;  4KYR A;  1YZ4 A;  5K9V A;  3D1O A;  3QCL A;  2PSZ A;  4RHG A;  2VEX A;  3ZL8 A;  3D44 A;  2NZ6 A;  3BRH A;  1G4U S;  2I4H A;  1ZCL A;  2BV5 A;  3EMU A;  1OHE A;  3V0F A;  2A3K A;  5BZZ A;  2F6F A;  3S4E A;  2GWO A;  4GE5 A;  3N0A A;  2FH7 A;  4GE6 A;  4BUB A;  1LAR A;  3O4T A;  2Y96 A;  4QUN A;  4HRF A;  1NNY A;  3D1H A;  1G7G A;  4ZRT A;  1NO6 A;  2PBN A;  1WRM A;  3V0I A;  2GC5 A;  1JBV A;  2VOS A;  3QCE A;  4OHD A;  4OHL A;  3O4U A;  1SUG A;  3MOZ A;  2GJT A;  5KAA A;  1NZ7 A;  2B49 A;  3ZMQ A;  1Q6S A;  1WCH A;  2AM1 A;  2QBS A;  1PTT A;  1T48 A;  1GWZ A;  1NWL A;  2AHS A;  2G6Z A;  4KI9 A;  1J4X A;  5J8R A;  1FPZ A;  1VHR A;  3V0E A;  1OHD A;  2F6W A;  2I6M A;  2JFF A;  1OES A;  2QBQ A;  3F9A A;  2CNE A;  2P4D A;  1ECV A;  5K9W A;  5KAC A;  2F6Z A;  4R0S A;  3MVN A;  2CFV A;  5EHR A;  1I57 A;  2CM3 A;  4JNB A;  3MOW A;  3ZM5 A;  4GE2 A;  4OHI A;  2HVL A;  3N2A A;  4TVV A;  4GFV A;  3D9C A;  2BIJ A;  1PH0 A;  3QCB A;  3QCD A;  3S4O A;  5GTJ A;  3ZM1 A;  4Y2E A;  3EAX A;  2PQ5 A;  1PXH A;  3S3E A;  4PYH A;  4QBE A;  4NND A;  2BGE A;  5BUG A;  4HJQ A;  2JFG A;  5M43 A;  1U25 A;  2CJZ A;  1BZC A;  2VOR A;  1JLN A;  2CM7 A;  2Y2F A;  4ZI4 A;  4UAG A;  1LYV A;  3QCC A;  2JJD A;  3F81 A;  1PTV A;  4YR8 B;  1GQQ A;  3LJ8 A;  3AWG A;  2QEP A;  2B4O A;  3A5K A;  3F9B A;  4WTY A;  4H1O A;  3PS5 A;  1Q6T A;  1U26 A;  1G7F A;  1QXK A;  4GWF A;  3S3F A;  1X24 A;  4NYH A;  3O5X A;  2VEV A;  1I9S A;  2OUD A;  2I3R A;  3ZV2 A;  1Q6M A;  4R0T A;  2HCM A;  1BZJ A;  4DGX A;  4AZ1 A;  2JFH A;  3QKP A;  4WU2 A;  3QCF A;  4B04 A;  4WU3 A;  2VEU A;  3D1Q A;  3RO1 A;  2E0T A;  2PI7 A;  3ZM2 A;  1PTY A;  2F46 A;  2DXP A;  1EEN A;  1RPM A;  5IBS A;  1OET A;  2QBP A;  1LQF A;  1R6H A;  1KAK A;  3MMJ A;  2J16 B;  3GXH A;  2UUP A;  4WOH A;  1EEH A;  1Q6N A;  4H34 A;  1XXV A;  1FGS A;  2F6V A;  3V0G A;  2OOQ A;  1G4W R;  3QCH A;  1OEM X;  2I3U A;  2Y68 A;  3QCM A;  4QAP A;  2NTA A;  2I4E A;  1YPT A;  2CNI A;  3SR9 A;  2UAG A;  2NT7 A;  4YAA A;  5BX1 A;  3S3K A;  4RH9 A;  3V0D A;  4GS0 A;  2I6O A;  4D3Q A;  3EB1 A;  5A5F A;  4NWG A;  1C88 A;  2ESB A;  4IKC A;  5K24 A;  2VTD A;  4C12 A;  2Q05 A;  3QCG A;  1I9T A;  2FJN A;  1OHC A;  4KYQ A;  1GQY A;  5KA0 A;  5I6V A;  3QCK A;  1PTU A;  2CMB A;  1ONY A;  1PA1 A;  3LK7 A;  1YFO A;  1FQ1 A;  3I80 A;  2B3O A;  5K22 A;  3CM3 A;  2BGD A;  2GCA A;  2F71 A;  2I6J A;  1OEO X;  4CVL A;  1L8K A;  1AAX A;  4D3P A;  2MBC A; 
#chains in the Genus database with same CATH homology
 1NL9 A;  4R30 A;  1BZH A;  1XM2 A;  2CNG A;  5KA1 A;  1ZC0 A;  4RI4 A;  1ZCK A;  3BLU A;  3D42 A;  1C83 A;  3QCN A;  2CNF A;  2HC2 A;  4S0G A;  1P15 A;  3QKQ A;  2I1Y A;  3CWE A;  3H2X A;  2QDP A;  1RXD A;  2FJM A;  4QBW A;  2H4K A;  4BPC A;  2OZ5 A;  2G59 A;  2BZL A;  1PA9 A;  1Q1M A;  4RI5 A;  2CMC A;  1A5Y A;  3F41 A;  3RZ2 A;  4NWF A;  1OEV A;  2H03 A;  5IBM A;  1G1H A;  2NT2 A;  3QCI A;  2VEY A;  1L8G A;  3I36 A;  1YN9 A;  3AWE A;  2B07 A;  1C84 A;  1C87 A;  1T4J A;  2QCJ A;  3ZMP A;  1M3G A;  4RKK A;  5KA2 A;  2CM8 A;  3SME A;  2WGP A;  5LXQ B;  2YDU A;  4QUM A;  2B4S A;  4GRZ A;  4ERC A;  4Z6B A;  2H4G A;  4NX8 A;  5MMZ B;  1YTS A;  2OC3 A;  2NLK A;  2I75 A;  2I4G A;  2NV5 A;  2CNH A;  4JBC A;  2HB1 A;  3EZZ A;  2P6X A;  4RDD A;  1OEU A;  5KA3 A;  1YGR A;  4ICZ A;  1U24 A;  1G1F A;  4ZN5 A;  1Q6P A;  2I6P A;  1D5R A;  4MBB A;  2B4P A;  2HNQ A;  1WAX A;  5EHP A;  3ZM0 A;  3ZM3 A;  2IMG A;  2C7S A;  2H02 A;  3O3L A;  5BZX A;  2HXP A;  1EEO A;  5HDE A;  5KA9 A;  2F70 A;  3EU0 A;  1KAV A;  2F6Y A;  5KA4 A;  5K25 A;  2QDM A;  4PVG A;  3AWF A;  1XRI A;  1ZZW A;  2J16 A;  1V3A A;  2J17 A;  5KAB A;  3GXG A;  4QAH A;  3A5J A;  2RF6 A;  1QZ0 A;  2QDC A;  4D3R A;  2I6I A;  3QCJ A;  3OLR A;  4GRY A;  1YTN A;  2M3V A;  1C86 A;  2SHP A;  1C85 A;  1FPR A;  3I7Z A;  1GFY A;  1NWE A;  3U96 A;  2QCT A;  2I42 A;  3V0H A;  1XBO A;  2I5X A;  4HJP A;  3OMH A;  2Q47 A;  4RH5 A;  1T49 A;  2PA5 A;  1YWF A;  3M4U A;  2HC1 A;  5KAD A;  2AZR A;  4JMK A;  2VEW A;  3BM8 A;  1JF7 A;  2CMA A;  3BLT A;  3F99 A;  3O4S A;  2GP0 A;  1YTW A;  3V0J A;  5K23 A;  2A8B A;  4BJO A;  5AWX A;  4GFU A;  5KA7 A;  1Q6J A;  4I8N A;  2HNP A;  2H4V A;  3RGO A;  2H04 A;  2HY3 A;  1ONZ A;  4OHH A;  5KA8 A;  4J51 A;  4Y14 A;  1MKP A;  2CM2 A;  4DGP A;  2F6T A;  3NME A;  2ZN7 A;  1XXP A;  3S3H A;  1PYN A;  2PT0 A;  4JMJ A;  2C46 A;  2B4U A;  2R0B A;  3RGQ A;  1G1G A;  1YGU A;  2ZMM A;  2QBR A;  3B7O A;  4OHE A;  4KYR A;  1YZ4 A;  5K9V A;  3D1O A;  3QCL A;  2PSZ A;  4RHG A;  2VEX A;  3D44 A;  2NZ6 A;  3BRH A;  1G4U S;  2I4H A;  1ZCL A;  2BV5 A;  3EMU A;  1OHE A;  3V0F A;  2A3K A;  5BZZ A;  2F6F A;  3S4E A;  2GWO A;  4GE5 A;  3N0A A;  2FH7 A;  4GE6 A;  1LAR A;  3O4T A;  2Y96 A;  4QUN A;  4HRF A;  1NNY A;  3D1H A;  1G7G A;  4ZRT A;  1NO6 A;  2PBN A;  1WRM A;  3V0I A;  3QCE A;  4OHD A;  4OHL A;  3O4U A;  1SUG A;  3MOZ A;  2GJT A;  5KAA A;  1NZ7 A;  2B49 A;  3ZMQ A;  1Q6S A;  1WCH A;  2QBS A;  1PTT A;  1T48 A;  1GWZ A;  1NWL A;  2AHS A;  2G6Z A;  4KI9 A;  1J4X A;  5J8R A;  1FPZ A;  1VHR A;  3V0E A;  1OHD A;  2F6W A;  2I6M A;  1OES A;  2QBQ A;  3F9A A;  2CNE A;  2P4D A;  1ECV A;  5K9W A;  5KAC A;  2F6Z A;  4R0S A;  2CFV A;  5EHR A;  1I57 A;  2CM3 A;  4JNB A;  3MOW A;  4GE2 A;  4OHI A;  2HVL A;  4TVV A;  4GFV A;  3D9C A;  2BIJ A;  1PH0 A;  3QCB A;  3QCD A;  3S4O A;  5GTJ A;  3ZM1 A;  4Y2E A;  3EAX A;  2PQ5 A;  1PXH A;  3S3E A;  4PYH A;  4QBE A;  4NND A;  2BGE A;  5BUG A;  4HJQ A;  5M43 A;  1U25 A;  2CJZ A;  1BZC A;  1JLN A;  2CM7 A;  2Y2F A;  4ZI4 A;  1LYV A;  3QCC A;  2JJD A;  3F81 A;  1PTV A;  4YR8 B;  3LJ8 A;  3AWG A;  2QEP A;  2B4O A;  3A5K A;  3F9B A;  4WTY A;  4H1O A;  3PS5 A;  1Q6T A;  1U26 A;  1G7F A;  1QXK A;  4GWF A;  3S3F A;  1X24 A;  4NYH A;  3O5X A;  2VEV A;  1I9S A;  2OUD A;  2I3R A;  3ZV2 A;  1Q6M A;  4R0T A;  2HCM A;  1BZJ A;  4DGX A;  4AZ1 A;  3QKP A;  4WU2 A;  3QCF A;  4B04 A;  4WU3 A;  2VEU A;  3D1Q A;  3RO1 A;  2E0T A;  2PI7 A;  3ZM2 A;  1PTY A;  2F46 A;  2DXP A;  1EEN A;  1RPM A;  5IBS A;  1OET A;  2QBP A;  1LQF A;  1R6H A;  1KAK A;  3MMJ A;  2J16 B;  3GXH A;  4WOH A;  1Q6N A;  4H34 A;  1XXV A;  2F6V A;  3V0G A;  2OOQ A;  1G4W R;  3QCH A;  1OEM X;  2I3U A;  3QCM A;  4QAP A;  2NTA A;  2I4E A;  1YPT A;  2CNI A;  3SR9 A;  2NT7 A;  4YAA A;  5BX1 A;  3S3K A;  4RH9 A;  3V0D A;  4GS0 A;  2I6O A;  4D3Q A;  3EB1 A;  4NWG A;  1C88 A;  2ESB A;  4IKC A;  5K24 A;  2Q05 A;  3QCG A;  1I9T A;  2FJN A;  1OHC A;  4KYQ A;  5KA0 A;  5I6V A;  3QCK A;  1PTU A;  2CMB A;  1ONY A;  1PA1 A;  1YFO A;  1FQ1 A;  3I80 A;  2B3O A;  5K22 A;  3CM3 A;  2BGD A;  2F71 A;  2I6J A;  1OEO X;  1L8K A;  1AAX A;  4D3P A;  2MBC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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