4J51A

Cyrstal structure of protein tyrosine phosphatase lyp catalytic domain complex with small molecular inhibitor l75n04
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
303
structure length
302
Chain Sequence
MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune Diseases.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 108
structure length 302
sequence length 303
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2013-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4j51A00
5BZXA 5KA7A 1FPZA 1NL9A 2JJDA 2HNQA 1PTTA 2F6FA 3N0AA 3S3EA 2QDCA 5KABA 3MOWA 3H2XA 1NZ7A 4R0SA 1Q6SA 2SHPA 3D1HA 4OHIA 1G4US 4H1OA 3D1OA 3QCFA 4OHHA 1G4WR 2B07A 3O4UA 2ESBA 1GWZA 1WCHA 4QAHA 1ZCLA 4OHLA 3D42A 4GFVA 3CWEA 1QZ0A 3RGOA 3A5JA 3QKPA 1G7FA 4PYHA 2P6XA 4QAPA 2QBPA 1YGRA 3QCLA 3ZMPA 4HJQA 4JMKA 1ONZA 1XBOA 3CM3A 3BLTA 5K23A 1YFOA 2QEPA 5KA1A 3QCJA 3EU0A 4NX8A 1LYVA 2I6IA 1ZCKA 3QCKA 2PQ5A 2IMGA 4JBCA 2J17A 1X24A 3S4EA 4KYQA 1PYNA 2GP0A 1XRIA 2CNGA 4ZRTA 3ZM2A 5HDEA 2BV5A 3O3LA 3BLUA 2PI7A 1PXHA 1T48A 1C86A 3SMEA 2HNPA 5BUGA 2NZ6A 3BRHA 1KAVA 2I3RA 3F41A 4Y2EA 1XM2A 5KA0A 3I80A 1P15A 2CNIA 3F9AA 2VEXA 1V3AA 1U25A 4RI5A 4GRYA 3V0GA 1OETA 2B4OA 1LARA 1GFYA 1Q6NA 1I9SA 1C84A 2PA5A 3EMUA 1OEMX 4NWFA 5KA8A 4B04A 1I57A 4JMJA 1JLNA 5GTJA 2QBRA 3LJ8A 2QCJA 4GFUA 4GWFA 3ZMQA 2H4GA 4WOHA 4WTYA 2VEUA 1PTYA 2GWOA 3QKQA 1KAKA 1SUGA 5EHPA 4D3PA 2AZRA 3O5XA 5IBSA 3D44A 1FQ1A 3QCIA 1YWFA 5KA9A 1U24A 2B3OA 2ZN7A 2QDMA 2I6OA 1WAXA 1YPTA 4YAAA 4RDDA 3S4OA 3QCHA 3D9CA 3I7ZA 4RI4A 1J4XA 5BX1A 1OEVA 1ECVA 2FH7A 3ZM1A 4RH5A 2FJNA 4KYRA 3V0EA 2BIJA 2HVLA 3QCCA 3EB1A 2CMAA 1PA1A 2HC2A 2R0BA 2QBQA 3SR9A 3RZ2A 2I42A 2PSZA 2QDPA 4IKCA 3BM8A 2NLKA 2A8BA 4ZI4A 1T49A 2I4EA 1XXVA 1EEOA 1EENA 4OHEA 4OHDA 2OC3A 4ZN5A 2VEVA 4H34A 2CJZA 2F70A 2I4GA 4R0TA 1YGUA 2I4HA 1R6HA 2CM3A 3M4UA 4WU2A 3V0DA 3V0IA 4MBBA 1YZ4A 2CMBA 4QBWA 3ZM0A 2CFVA 4QUNA 3F99A 3AWFA 5KADA 3RO1A 5KA3A 3QCBA 2H03A 5KACA 5K22A 2CM7A 2NT2A 2Y2FA 2F46A 2WGPA 1NO6A 1C85A 2A3KA 1ONYA 2I75A 1OHEA 2C7SA 4RKKA 2AHSA 2H04A 1QXKA 5KAAA 1I9TA 3V0HA 5KA4A 2P4DA 3S3KA 1C88A 2F6WA 5K9VA 1YTWA 3MMJA 2VEWA 1A5YA 2CNEA 5IBMA 1L8GA 1OHCA 2HXPA 2Q05A 2RF6A 3OLRA 4GE5A 2G59A 1NNYA 1ZC0A 3GXGA 1WRMA 1BZJA 3OMHA 1PTUA 1NWLA 2HB1A 1Q6PA 2H4VA 1Q6TA 2F71A 2HY3A 4GE6A 5KA2A 2CM8A 3ZM3A 1G7GA 1RPMA 1Q6JA 2B4UA 2VEYA 3D1QA 2DXPA 2Q47A 3B7OA 1JF7A 4PVGA 4GS0A 1U26A 2I5XA 1G1GA 2H4KA 1LQFA 2HC1A 2HCMA 4WU3A 2FJMA 3QCEA 2G6ZA 1G1HA 3QCGA 1RXDA 2M3VA 4S0GA 3U96A 1NWEA 1T4JA 2C46A 1C87A 3S3HA 1OHDA 2CNHA 3A5KA 4YR8B 5K24A 5BZZA 4KI9A 2F6VA 4JNBA 5MMZB 3EAXA 4ICZA 1BZHA 2NT7A 2QCTA 4AZ1A 3AWEA 1M3GA 2PBNA 4BPCA 3ZV2A 5LXQB 4GE2A 3QCNA 5K25A 2BGEA 3V0FA 1BZCA 4DGXA 4ERCA 1C83A 3QCMA 2YDUA 1L8KA 4NWGA 5J8RA 2J16B 4HRFA 4GRZA 2I6MA 1OEOX 3PS5A 1FPRA 3O4TA 1Q6MA 2ZMMA 3O4SA 3F81A 4D3RA 2F6ZA 2MBCA 1AAXA 1VHRA 2BZLA 5I6VA 2GJTA 2I6PA 2B49A 1PTVA 4QBEA 2E0TA 1MKPA 3AWGA 4BJOA 1PA9A 2I6JA 1G1FA 2OUDA 4TVVA 3I36A 4RH9A 4Y14A 2BGDA 4Z6BA 5K9WA 2OZ5A 4DGPA 3F9BA 1YTNA 2F6TA 2QBSA 2NTAA 4NNDA 4NYHA 1D5RA 3RGQA 1XXPA 1PH0A 5M43A 1YN9A 3MOZA 5EHRA 2CNFA 2PT0A 5AWXA 2OOQA 1YTSA 4QUMA 2CMCA 2NV5A 2I3UA 3EZZA 4D3QA 1OESA 4R30A 1OEUA 4I8NA 2F6YA 2H02A 2CM2A 2Y96A 4J51A 1ZZWA 2I1YA 4RHGA 2B4PA 2B4SA 3S3FA 1Q1MA 4HJPA 2J16A 3V0JA 3QCDA 3GXHA 3NMEA
chains in the Genus database with same CATH superfamily
2VTEA 5BZXA 5KA7A 1FPZA 1NL9A 2JJDA 2HNQA 1PTTA 2F6FA 3N0AA 3S3EA 2QDCA 5KABA 3MOWA 1P31A 3H2XA 1NZ7A 4R0SA 1Q6SA 2SHPA 4ZIYA 3D1HA 4OHIA 1G4US 4H1OA 3D1OA 2GCBA 3QCFA 4OHHA 1G4WR 2B07A 3O4UA 2ESBA 1GWZA 1WCHA 4QAHA 1ZCLA 4OHLA 3D42A 4GFVA 3CWEA 1QZ0A 3RGOA 3A5JA 3QKPA 1G7FA 4PYHA 2P6XA 4QAPA 2QBPA 4CVLA 1YGRA 3QCLA 3ZMPA 4HJQA 4JMKA 1ONZA 1XBOA 3BLTA 3CM3A 5K23A 1YFOA 2QEPA 5KA1A 3QCJA 3EU0A 4NX8A 1LYVA 2I6IA 1ZCKA 3QCKA 2PQ5A 2IMGA 4JBCA 2J17A 1X24A 3S4EA 4KYQA 1PYNA 2Y1OA 2GP0A 1XRIA 2CNGA 4ZRTA 3ZM2A 5HDEA 2BV5A 3O3LA 3BLUA 2PI7A 4C12A 1PXHA 1T48A 1C86A 1E8CA 3SMEA 2HNPA 5BUGA 2NZ6A 3BRHA 1KAVA 1FGSA 2I3RA 3F41A 2GC6A 4Y2EA 1XM2A 5KA0A 3I80A 1P15A 2CNIA 3F9AA 2VEXA 1V3AA 1U25A 4RI5A 2UUOA 4GRYA 3MVNA 3V0GA 1OETA 2B4OA 1LARA 3PYZA 1GFYA 1Q6NA 1I9SA 1C84A 2VORA 2PA5A 3EMUA 1OEMX 4NWFA 2XJAA 5KA8A 4B04A 1I57A 4JMJA 1JLNA 5GTJA 2QBRA 1W7KA 3LJ8A 2QCJA 4GFUA 4GWFA 3ZMQA 2H4GA 4WOHA 4WTYA 2VEUA 1PTYA 2GWOA 3QKQA 1KAKA 1SUGA 5EHPA 4D3PA 2AZRA 3O5XA 5IBSA 3D44A 2XPCA 5A5FA 1FQ1A 4HV4A 3QCIA 1YWFA 5KA9A 1U24A 2B3OA 2ZN7A 2QDMA 2I6OA 1WAXA 1YPTA 4YAAA 4RDDA 3S4OA 3QCHA 3D9CA 3I7ZA 4RI4A 2GC5A 1J4XA 2WJPA 5BX1A 1OEVA 4BUBA 1ECVA 2FH7A 3ZM1A 4RH5A 2FJNA 4KYRA 3V0EA 2BIJA 2HVLA 3QCCA 3EB1A 2CMAA 1PA1A 2HC2A 2R0BA 2QBQA 3SR9A 3RZ2A 2AM1A 2I42A 2PSZA 2JFGA 2QDPA 4IKCA 3BM8A 2NLKA 2A8BA 4ZI4A 1T49A 2I4EA 1XXVA 1EEOA 1EENA 4OHEA 1P3DA 4OHDA 2OC3A 4ZN5A 2VEVA 4H34A 2CJZA 2F70A 2I4GA 4R0TA 1YGUA 2I4HA 1R6HA 2CM3A 3M4UA 4WU2A 3V0DA 3V0IA 4MBBA 1YZ4A 2CMBA 4QBWA 3ZM0A 2CFVA 4QUNA 3F99A 3AWFA 5KADA 1EEHA 3RO1A 5KA3A 2H03A 3QCBA 5KACA 5K22A 2CM7A 2NT2A 2Y2FA 2F46A 2WGPA 1NO6A 1C85A 2A3KA 1ONYA 2I75A 1OHEA 2C7SA 4RKKA 2AHSA 2H04A 1QXKA 5KAAA 1I9TA 3V0HA 5KA4A 2P4DA 3S3KA 1C88A 2F6WA 5K9VA 1YTWA 3MMJA 2VEWA 1A5YA 4UAGA 2CNEA 2X5OA 5IBMA 1L8GA 1OHCA 2HXPA 2Q05A 2RF6A 3OLRA 4GE5A 2G59A 1NNYA 1ZC0A 2JFHA 3GXGA 1WRMA 1BZJA 3OMHA 4QDIA 2WTZA 1PTUA 1NWLA 2HB1A 1Q6PA 2GCAA 2H4VA 4QF5A 1Q6TA 2F71A 2HY3A 4GE6A 5KA2A 2CM8A 3ZM3A 4BUCA 1GQYA 1G7GA 2F00A 1GQQA 1RPMA 1Q6JA 2B4UA 2VEYA 2JFFA 3D1QA 2DXPA 3UAGA 2Q47A 1W78A 3B7OA 1JF7A 2Y67A 4PVGA 4GS0A 1U26A 2I5XA 2VTDA 1G1GA 2H4KA 1LQFA 2HC1A 2HCMA 4WU3A 2FJMA 3HN7A 3QCEA 5A5EA 2G6ZA 1G1HA 3QCGA 1RXDA 2VOSA 1GG4A 2M3VA 4S0GA 3U96A 1NWEA 1T4JA 1UAGA 2C46A 1C87A 3NRSA 3S3HA 1OHDA 2CNHA 3A5KA 4YR8B 3ZM5A 5K24A 5BZZA 2AM2A 4KI9A 2F6VA 4JNBA 5MMZB 3EAXA 4ICZA 1BZHA 2NT7A 2QCTA 4AZ1A 3AWEA 1M3GA 1J6UA 2PBNA 4BPCA 3ZV2A 5LXQB 4GE2A 3QCNA 5K25A 2BGEA 4CVKA 3N2AA 3V0FA 1BZCA 4DGXA 4ERCA 1C83A 3QCMA 2YDUA 1L8KA 1JBVA 4NWGA 5J8RA 2J16B 4HRFA 4GRZA 1JBWA 2I6MA 1OEOX 3PS5A 1FPRA 3O4TA 1Q6MA 2ZMMA 3O4SA 3F81A 4D3RA 2F6ZA 2MBCA 1AAXA 3QCZA 1VHRA 2Y68A 2BZLA 5I6VA 2GJTA 2I6PA 2B49A 1PTVA 4QBEA 2E0TA 1MKPA 3AWGA 4BJOA 1PA9A 2I6JA 1G1FA 2OUDA 4TVVA 3I36A 4RH9A 2Y66A 4Y14A 2BGDA 4Z6BA 5K9WA 2OZ5A 4DGPA 3F9BA 1YTNA 2F6TA 2QBSA 2NTAA 1E0DA 4NNDA 4NYHA 3ZL8A 1D5RA 3RGQA 1XXPA 1PH0A 5M43A 1YN9A 1O5ZA 3MOZA 5EHRA 2CNFA 2PT0A 5AWXA 2OOQA 1YTSA 4QUMA 2CMCA 2NV5A 2I3UA 3EZZA 4CVMA 4C13A 4D3QA 1OESA 3LK7A 2UUPA 4R30A 1OEUA 4I8NA 2F6YA 2H02A 2CM2A 2Y96A 4J51A 1ZZWA 2I1YA 4RHGA 3ZM6A 2B4PA 2B4SA 2UAGA 3S3FA 1Q1MA 4HJPA 2J16A 3V0JA 3QCDA 3GXHA 3NMEA
chains in the Genus database with same CATH topology
5BZXA 5KA7A 1FPZA 1NL9A 2JJDA 2HNQA 1PTTA 2F6FA 3N0AA 3S3EA 2QDCA 5KABA 3MOWA 3H2XA 1NZ7A 4R0SA 1Q6SA 2SHPA 3D1HA 4OHIA 1G4US 4H1OA 3D1OA 3QCFA 4OHHA 1G4WR 2B07A 3O4UA 2ESBA 1GWZA 1WCHA 4QAHA 1ZCLA 4OHLA 3D42A 4GFVA 3CWEA 1QZ0A 3RGOA 3A5JA 3QKPA 1G7FA 4PYHA 2P6XA 4QAPA 2QBPA 1YGRA 3QCLA 3ZMPA 4HJQA 4JMKA 1ONZA 1XBOA 3CM3A 3BLTA 5K23A 1YFOA 2QEPA 5KA1A 3QCJA 3EU0A 4NX8A 1LYVA 2I6IA 1ZCKA 3QCKA 2PQ5A 2IMGA 4JBCA 2J17A 1X24A 3S4EA 4KYQA 1PYNA 2GP0A 1XRIA 2CNGA 4ZRTA 3ZM2A 5HDEA 2BV5A 3O3LA 3BLUA 2PI7A 1PXHA 1T48A 1C86A 3SMEA 2HNPA 5BUGA 2NZ6A 3BRHA 1KAVA 2I3RA 3F41A 4Y2EA 1XM2A 5KA0A 3I80A 1P15A 2CNIA 3F9AA 2VEXA 1V3AA 1U25A 4RI5A 4GRYA 3V0GA 1OETA 2B4OA 1LARA 1GFYA 1Q6NA 1I9SA 1C84A 2PA5A 3EMUA 1OEMX 4NWFA 5KA8A 4B04A 1I57A 4JMJA 1JLNA 5GTJA 2QBRA 3LJ8A 2QCJA 4GFUA 4GWFA 3ZMQA 2H4GA 4WOHA 4WTYA 2VEUA 1PTYA 2GWOA 3QKQA 1KAKA 1SUGA 5EHPA 4D3PA 2AZRA 3O5XA 5IBSA 3D44A 1FQ1A 3QCIA 1YWFA 5KA9A 1U24A 2B3OA 2ZN7A 2QDMA 2I6OA 1WAXA 1YPTA 4YAAA 4RDDA 3S4OA 3QCHA 3D9CA 3I7ZA 4RI4A 1J4XA 5BX1A 1OEVA 1ECVA 2FH7A 3ZM1A 4RH5A 2FJNA 4KYRA 3V0EA 2BIJA 2HVLA 3QCCA 3EB1A 2CMAA 1PA1A 2HC2A 2R0BA 2QBQA 3SR9A 3RZ2A 2I42A 2PSZA 2QDPA 4IKCA 3BM8A 2NLKA 2A8BA 4ZI4A 1T49A 2I4EA 1XXVA 1EEOA 1EENA 4OHEA 4OHDA 2OC3A 4ZN5A 2VEVA 4H34A 2CJZA 2F70A 2I4GA 4R0TA 1YGUA 2I4HA 1R6HA 2CM3A 3M4UA 4WU2A 3V0DA 3V0IA 4MBBA 1YZ4A 2CMBA 4QBWA 3ZM0A 2CFVA 4QUNA 3F99A 3AWFA 5KADA 3RO1A 5KA3A 3QCBA 2H03A 5KACA 5K22A 2CM7A 2NT2A 2Y2FA 2F46A 2WGPA 1NO6A 1C85A 2A3KA 1ONYA 2I75A 1OHEA 2C7SA 4RKKA 2AHSA 2H04A 1QXKA 5KAAA 1I9TA 3V0HA 5KA4A 2P4DA 3S3KA 1C88A 2F6WA 5K9VA 1YTWA 3MMJA 2VEWA 1A5YA 2CNEA 5IBMA 1L8GA 1OHCA 2HXPA 2Q05A 2RF6A 3OLRA 4GE5A 2G59A 1NNYA 1ZC0A 3GXGA 1WRMA 1BZJA 3OMHA 1PTUA 1NWLA 2HB1A 1Q6PA 2H4VA 1Q6TA 2F71A 2HY3A 4GE6A 5KA2A 2CM8A 3ZM3A 1G7GA 1RPMA 1Q6JA 2B4UA 2VEYA 3D1QA 2DXPA 2Q47A 3B7OA 1JF7A 4PVGA 4GS0A 1U26A 2I5XA 1G1GA 2H4KA 1LQFA 2HC1A 2HCMA 4WU3A 2FJMA 3QCEA 2G6ZA 1G1HA 3QCGA 1RXDA 2M3VA 4S0GA 3U96A 1NWEA 1T4JA 2C46A 1C87A 3S3HA 1OHDA 2CNHA 3A5KA 4YR8B 5K24A 5BZZA 4KI9A 2F6VA 4JNBA 5MMZB 3EAXA 4ICZA 1BZHA 2NT7A 2QCTA 4AZ1A 3AWEA 1M3GA 2PBNA 4BPCA 3ZV2A 5LXQB 4GE2A 3QCNA 5K25A 2BGEA 3V0FA 1BZCA 4DGXA 4ERCA 1C83A 3QCMA 2YDUA 1L8KA 4NWGA 5J8RA 2J16B 4HRFA 4GRZA 2I6MA 1OEOX 3PS5A 1FPRA 3O4TA 1Q6MA 2ZMMA 3O4SA 3F81A 4D3RA 2F6ZA 2MBCA 1AAXA 1VHRA 2BZLA 5I6VA 2GJTA 2I6PA 2B49A 1PTVA 4QBEA 2E0TA 1MKPA 3AWGA 4BJOA 1PA9A 2I6JA 1G1FA 2OUDA 4TVVA 3I36A 4RH9A 4Y14A 2BGDA 4Z6BA 5K9WA 2OZ5A 4DGPA 3F9BA 1YTNA 2F6TA 2QBSA 2NTAA 4NNDA 4NYHA 1D5RA 3RGQA 1XXPA 1PH0A 5M43A 1YN9A 3MOZA 5EHRA 2CNFA 2PT0A 5AWXA 2OOQA 1YTSA 4QUMA 2CMCA 2NV5A 2I3UA 3EZZA 4D3QA 1OESA 4R30A 1OEUA 4I8NA 2F6YA 2H02A 2CM2A 2Y96A 4J51A 1ZZWA 2I1YA 4RHGA 2B4PA 2B4SA 3S3FA 1Q1MA 4HJPA 2J16A 3V0JA 3QCDA 3GXHA 3NMEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BZX A;  5KA7 A;  1FPZ A;  1NL9 A;  2JJD A;  2HNQ A;  1PTT A;  2F6F A;  3N0A A;  3S3E A;  2QDC A;  5KAB A;  3MOW A;  3H2X A;  1NZ7 A;  4R0S A;  1Q6S A;  2SHP A;  3D1H A;  4OHI A;  1G4U S;  4H1O A;  3D1O A;  3QCF A;  4OHH A;  1G4W R;  2B07 A;  3O4U A;  2ESB A;  1GWZ A;  1WCH A;  4QAH A;  1ZCL A;  4OHL A;  3D42 A;  4GFV A;  3CWE A;  1QZ0 A;  3RGO A;  3A5J A;  3QKP A;  1G7F A;  4PYH A;  2P6X A;  4QAP A;  2QBP A;  1YGR A;  3QCL A;  3ZMP A;  4HJQ A;  4JMK A;  1ONZ A;  1XBO A;  3CM3 A;  3BLT A;  5K23 A;  1YFO A;  2QEP A;  5KA1 A;  3QCJ A;  3EU0 A;  4NX8 A;  1LYV A;  2I6I A;  1ZCK A;  3QCK A;  2PQ5 A;  2IMG A;  4JBC A;  2J17 A;  1X24 A;  3S4E A;  4KYQ A;  1PYN A;  2GP0 A;  1XRI A;  2CNG A;  4ZRT A;  3ZM2 A;  5HDE A;  2BV5 A;  3O3L A;  3BLU A;  2PI7 A;  1PXH A;  1T48 A;  1C86 A;  3SME A;  2HNP A;  5BUG A;  2NZ6 A;  3BRH A;  1KAV A;  2I3R A;  3F41 A;  4Y2E A;  1XM2 A;  5KA0 A;  3I80 A;  1P15 A;  2CNI A;  3F9A A;  2VEX A;  1V3A A;  1U25 A;  4RI5 A;  4GRY A;  3V0G A;  1OET A;  2B4O A;  1LAR A;  1GFY A;  1Q6N A;  1I9S A;  1C84 A;  2PA5 A;  3EMU A;  1OEM X;  4NWF A;  5KA8 A;  4B04 A;  1I57 A;  4JMJ A;  1JLN A;  5GTJ A;  2QBR A;  3LJ8 A;  2QCJ A;  4GFU A;  4GWF A;  3ZMQ A;  2H4G A;  4WOH A;  4WTY A;  2VEU A;  1PTY A;  2GWO A;  3QKQ A;  1KAK A;  1SUG A;  5EHP A;  4D3P A;  2AZR A;  3O5X A;  5IBS A;  3D44 A;  1FQ1 A;  3QCI A;  1YWF A;  5KA9 A;  1U24 A;  2B3O A;  2ZN7 A;  2QDM A;  2I6O A;  1WAX A;  1YPT A;  4YAA A;  4RDD A;  3S4O A;  3QCH A;  3D9C A;  3I7Z A;  4RI4 A;  1J4X A;  5BX1 A;  1OEV A;  1ECV A;  2FH7 A;  3ZM1 A;  4RH5 A;  2FJN A;  4KYR A;  3V0E A;  2BIJ A;  2HVL A;  3QCC A;  3EB1 A;  2CMA A;  1PA1 A;  2HC2 A;  2R0B A;  2QBQ A;  3SR9 A;  3RZ2 A;  2I42 A;  2PSZ A;  2QDP A;  4IKC A;  3BM8 A;  2NLK A;  2A8B A;  4ZI4 A;  1T49 A;  2I4E A;  1XXV A;  1EEO A;  1EEN A;  4OHE A;  4OHD A;  2OC3 A;  4ZN5 A;  2VEV A;  4H34 A;  2CJZ A;  2F70 A;  2I4G A;  4R0T A;  1YGU A;  2I4H A;  1R6H A;  2CM3 A;  3M4U A;  4WU2 A;  3V0D A;  3V0I A;  4MBB A;  1YZ4 A;  2CMB A;  4QBW A;  3ZM0 A;  2CFV A;  4QUN A;  3F99 A;  3AWF A;  5KAD A;  3RO1 A;  5KA3 A;  3QCB A;  2H03 A;  5KAC A;  5K22 A;  2CM7 A;  2NT2 A;  2Y2F A;  2F46 A;  2WGP A;  1NO6 A;  1C85 A;  2A3K A;  1ONY A;  2I75 A;  1OHE A;  2C7S A;  4RKK A;  2AHS A;  2H04 A;  1QXK A;  5KAA A;  1I9T A;  3V0H A;  5KA4 A;  2P4D A;  3S3K A;  1C88 A;  2F6W A;  5K9V A;  1YTW A;  3MMJ A;  2VEW A;  1A5Y A;  2CNE A;  5IBM A;  1L8G A;  1OHC A;  2HXP A;  2Q05 A;  2RF6 A;  3OLR A;  4GE5 A;  2G59 A;  1NNY A;  1ZC0 A;  3GXG A;  1WRM A;  1BZJ A;  3OMH A;  1PTU A;  1NWL A;  2HB1 A;  1Q6P A;  2H4V A;  1Q6T A;  2F71 A;  2HY3 A;  4GE6 A;  5KA2 A;  2CM8 A;  3ZM3 A;  1G7G A;  1RPM A;  1Q6J A;  2B4U A;  2VEY A;  3D1Q A;  2DXP A;  2Q47 A;  3B7O A;  1JF7 A;  4PVG A;  4GS0 A;  1U26 A;  2I5X A;  1G1G A;  2H4K A;  1LQF A;  2HC1 A;  2HCM A;  4WU3 A;  2FJM A;  3QCE A;  2G6Z A;  1G1H A;  3QCG A;  1RXD A;  2M3V A;  4S0G A;  3U96 A;  1NWE A;  1T4J A;  2C46 A;  1C87 A;  3S3H A;  1OHD A;  2CNH A;  3A5K A;  4YR8 B;  5K24 A;  5BZZ A;  4KI9 A;  2F6V A;  4JNB A;  5MMZ B;  3EAX A;  4ICZ A;  1BZH A;  2NT7 A;  2QCT A;  4AZ1 A;  3AWE A;  1M3G A;  2PBN A;  4BPC A;  3ZV2 A;  5LXQ B;  4GE2 A;  3QCN A;  5K25 A;  2BGE A;  3V0F A;  1BZC A;  4DGX A;  4ERC A;  1C83 A;  3QCM A;  2YDU A;  1L8K A;  4NWG A;  5J8R A;  2J16 B;  4HRF A;  4GRZ A;  2I6M A;  1OEO X;  3PS5 A;  1FPR A;  3O4T A;  1Q6M A;  2ZMM A;  3O4S A;  3F81 A;  4D3R A;  2F6Z A;  2MBC A;  1AAX A;  1VHR A;  2BZL A;  5I6V A;  2GJT A;  2I6P A;  2B49 A;  1PTV A;  4QBE A;  2E0T A;  1MKP A;  3AWG A;  4BJO A;  1PA9 A;  2I6J A;  1G1F A;  2OUD A;  4TVV A;  3I36 A;  4RH9 A;  4Y14 A;  2BGD A;  4Z6B A;  5K9W A;  2OZ5 A;  4DGP A;  3F9B A;  1YTN A;  2F6T A;  2QBS A;  2NTA A;  4NND A;  4NYH A;  1D5R A;  3RGQ A;  1XXP A;  1PH0 A;  5M43 A;  1YN9 A;  3MOZ A;  5EHR A;  2CNF A;  2PT0 A;  5AWX A;  2OOQ A;  1YTS A;  4QUM A;  2CMC A;  2NV5 A;  2I3U A;  3EZZ A;  4D3Q A;  1OES A;  4R30 A;  1OEU A;  4I8N A;  2F6Y A;  2H02 A;  2CM2 A;  2Y96 A;  4J51 A;  1ZZW A;  2I1Y A;  4RHG A;  2B4P A;  2B4S A;  3S3F A;  1Q1M A;  4HJP A;  2J16 A;  3V0J A;  3QCD A;  3GXH A;  3NME A; 
#chains in the Genus database with same CATH topology
 2VTE A;  5BZX A;  5KA7 A;  1FPZ A;  1NL9 A;  2JJD A;  2HNQ A;  1PTT A;  2F6F A;  3N0A A;  3S3E A;  2QDC A;  5KAB A;  3MOW A;  1P31 A;  3H2X A;  1NZ7 A;  4R0S A;  1Q6S A;  2SHP A;  4ZIY A;  3D1H A;  4OHI A;  1G4U S;  4H1O A;  3D1O A;  2GCB A;  3QCF A;  4OHH A;  1G4W R;  2B07 A;  3O4U A;  2ESB A;  1GWZ A;  1WCH A;  4QAH A;  1ZCL A;  4OHL A;  3D42 A;  4GFV A;  3CWE A;  1QZ0 A;  3RGO A;  3A5J A;  3QKP A;  1G7F A;  4PYH A;  2P6X A;  4QAP A;  2QBP A;  4CVL A;  1YGR A;  3QCL A;  3ZMP A;  4HJQ A;  4JMK A;  1ONZ A;  1XBO A;  3BLT A;  3CM3 A;  5K23 A;  1YFO A;  2QEP A;  5KA1 A;  3QCJ A;  3EU0 A;  4NX8 A;  1LYV A;  2I6I A;  1ZCK A;  3QCK A;  2PQ5 A;  2IMG A;  4JBC A;  2J17 A;  1X24 A;  3S4E A;  4KYQ A;  1PYN A;  2Y1O A;  2GP0 A;  1XRI A;  2CNG A;  4ZRT A;  3ZM2 A;  5HDE A;  2BV5 A;  3O3L A;  3BLU A;  2PI7 A;  4C12 A;  1PXH A;  1T48 A;  1C86 A;  1E8C A;  3SME A;  2HNP A;  5BUG A;  2NZ6 A;  3BRH A;  1KAV A;  1FGS A;  2I3R A;  3F41 A;  2GC6 A;  4Y2E A;  1XM2 A;  5KA0 A;  3I80 A;  1P15 A;  2CNI A;  3F9A A;  2VEX A;  1V3A A;  1U25 A;  4RI5 A;  2UUO A;  4GRY A;  3MVN A;  3V0G A;  1OET A;  2B4O A;  1LAR A;  3PYZ A;  1GFY A;  1Q6N A;  1I9S A;  1C84 A;  2VOR A;  2PA5 A;  3EMU A;  1OEM X;  4NWF A;  2XJA A;  5KA8 A;  4B04 A;  1I57 A;  4JMJ A;  1JLN A;  5GTJ A;  2QBR A;  1W7K A;  3LJ8 A;  2QCJ A;  4GFU A;  4GWF A;  3ZMQ A;  2H4G A;  4WOH A;  4WTY A;  2VEU A;  1PTY A;  2GWO A;  3QKQ A;  1KAK A;  1SUG A;  5EHP A;  4D3P A;  2AZR A;  3O5X A;  5IBS A;  3D44 A;  2XPC A;  5A5F A;  1FQ1 A;  4HV4 A;  3QCI A;  1YWF A;  5KA9 A;  1U24 A;  2B3O A;  2ZN7 A;  2QDM A;  2I6O A;  1WAX A;  1YPT A;  4YAA A;  4RDD A;  3S4O A;  3QCH A;  3D9C A;  3I7Z A;  4RI4 A;  2GC5 A;  1J4X A;  2WJP A;  5BX1 A;  1OEV A;  4BUB A;  1ECV A;  2FH7 A;  3ZM1 A;  4RH5 A;  2FJN A;  4KYR A;  3V0E A;  2BIJ A;  2HVL A;  3QCC A;  3EB1 A;  2CMA A;  1PA1 A;  2HC2 A;  2R0B A;  2QBQ A;  3SR9 A;  3RZ2 A;  2AM1 A;  2I42 A;  2PSZ A;  2JFG A;  2QDP A;  4IKC A;  3BM8 A;  2NLK A;  2A8B A;  4ZI4 A;  1T49 A;  2I4E A;  1XXV A;  1EEO A;  1EEN A;  4OHE A;  1P3D A;  4OHD A;  2OC3 A;  4ZN5 A;  2VEV A;  4H34 A;  2CJZ A;  2F70 A;  2I4G A;  4R0T A;  1YGU A;  2I4H A;  1R6H A;  2CM3 A;  3M4U A;  4WU2 A;  3V0D A;  3V0I A;  4MBB A;  1YZ4 A;  2CMB A;  4QBW A;  3ZM0 A;  2CFV A;  4QUN A;  3F99 A;  3AWF A;  5KAD A;  1EEH A;  3RO1 A;  5KA3 A;  2H03 A;  3QCB A;  5KAC A;  5K22 A;  2CM7 A;  2NT2 A;  2Y2F A;  2F46 A;  2WGP A;  1NO6 A;  1C85 A;  2A3K A;  1ONY A;  2I75 A;  1OHE A;  2C7S A;  4RKK A;  2AHS A;  2H04 A;  1QXK A;  5KAA A;  1I9T A;  3V0H A;  5KA4 A;  2P4D A;  3S3K A;  1C88 A;  2F6W A;  5K9V A;  1YTW A;  3MMJ A;  2VEW A;  1A5Y A;  4UAG A;  2CNE A;  2X5O A;  5IBM A;  1L8G A;  1OHC A;  2HXP A;  2Q05 A;  2RF6 A;  3OLR A;  4GE5 A;  2G59 A;  1NNY A;  1ZC0 A;  2JFH A;  3GXG A;  1WRM A;  1BZJ A;  3OMH A;  4QDI A;  2WTZ A;  1PTU A;  1NWL A;  2HB1 A;  1Q6P A;  2GCA A;  2H4V A;  4QF5 A;  1Q6T A;  2F71 A;  2HY3 A;  4GE6 A;  5KA2 A;  2CM8 A;  3ZM3 A;  4BUC A;  1GQY A;  1G7G A;  2F00 A;  1GQQ A;  1RPM A;  1Q6J A;  2B4U A;  2VEY A;  2JFF A;  3D1Q A;  2DXP A;  3UAG A;  2Q47 A;  1W78 A;  3B7O A;  1JF7 A;  2Y67 A;  4PVG A;  4GS0 A;  1U26 A;  2I5X A;  2VTD A;  1G1G A;  2H4K A;  1LQF A;  2HC1 A;  2HCM A;  4WU3 A;  2FJM A;  3HN7 A;  3QCE A;  5A5E A;  2G6Z A;  1G1H A;  3QCG A;  1RXD A;  2VOS A;  1GG4 A;  2M3V A;  4S0G A;  3U96 A;  1NWE A;  1T4J A;  1UAG A;  2C46 A;  1C87 A;  3NRS A;  3S3H A;  1OHD A;  2CNH A;  3A5K A;  4YR8 B;  3ZM5 A;  5K24 A;  5BZZ A;  2AM2 A;  4KI9 A;  2F6V A;  4JNB A;  5MMZ B;  3EAX A;  4ICZ A;  1BZH A;  2NT7 A;  2QCT A;  4AZ1 A;  3AWE A;  1M3G A;  1J6U A;  2PBN A;  4BPC A;  3ZV2 A;  5LXQ B;  4GE2 A;  3QCN A;  5K25 A;  2BGE A;  4CVK A;  3N2A A;  3V0F A;  1BZC A;  4DGX A;  4ERC A;  1C83 A;  3QCM A;  2YDU A;  1L8K A;  1JBV A;  4NWG A;  5J8R A;  2J16 B;  4HRF A;  4GRZ A;  1JBW A;  2I6M A;  1OEO X;  3PS5 A;  1FPR A;  3O4T A;  1Q6M A;  2ZMM A;  3O4S A;  3F81 A;  4D3R A;  2F6Z A;  2MBC A;  1AAX A;  3QCZ A;  1VHR A;  2Y68 A;  2BZL A;  5I6V A;  2GJT A;  2I6P A;  2B49 A;  1PTV A;  4QBE A;  2E0T A;  1MKP A;  3AWG A;  4BJO A;  1PA9 A;  2I6J A;  1G1F A;  2OUD A;  4TVV A;  3I36 A;  4RH9 A;  2Y66 A;  4Y14 A;  2BGD A;  4Z6B A;  5K9W A;  2OZ5 A;  4DGP A;  3F9B A;  1YTN A;  2F6T A;  2QBS A;  2NTA A;  1E0D A;  4NND A;  4NYH A;  3ZL8 A;  1D5R A;  3RGQ A;  1XXP A;  1PH0 A;  5M43 A;  1YN9 A;  1O5Z A;  3MOZ A;  5EHR A;  2CNF A;  2PT0 A;  5AWX A;  2OOQ A;  1YTS A;  4QUM A;  2CMC A;  2NV5 A;  2I3U A;  3EZZ A;  4CVM A;  4C13 A;  4D3Q A;  1OES A;  3LK7 A;  2UUP A;  4R30 A;  1OEU A;  4I8N A;  2F6Y A;  2H02 A;  2CM2 A;  2Y96 A;  4J51 A;  1ZZW A;  2I1Y A;  4RHG A;  3ZM6 A;  2B4P A;  2B4S A;  2UAG A;  3S3F A;  1Q1M A;  4HJP A;  2J16 A;  3V0J A;  3QCD A;  3GXH A;  3NME A; 
#chains in the Genus database with same CATH homology
 5BZX A;  5KA7 A;  1FPZ A;  1NL9 A;  2JJD A;  2HNQ A;  1PTT A;  2F6F A;  3N0A A;  3S3E A;  2QDC A;  5KAB A;  3MOW A;  3H2X A;  1NZ7 A;  4R0S A;  1Q6S A;  2SHP A;  3D1H A;  4OHI A;  1G4U S;  4H1O A;  3D1O A;  3QCF A;  4OHH A;  1G4W R;  2B07 A;  3O4U A;  2ESB A;  1GWZ A;  1WCH A;  4QAH A;  1ZCL A;  4OHL A;  3D42 A;  4GFV A;  3CWE A;  1QZ0 A;  3RGO A;  3A5J A;  3QKP A;  1G7F A;  4PYH A;  2P6X A;  4QAP A;  2QBP A;  1YGR A;  3QCL A;  3ZMP A;  4HJQ A;  4JMK A;  1ONZ A;  1XBO A;  3CM3 A;  3BLT A;  5K23 A;  1YFO A;  2QEP A;  5KA1 A;  3QCJ A;  3EU0 A;  4NX8 A;  1LYV A;  2I6I A;  1ZCK A;  3QCK A;  2PQ5 A;  2IMG A;  4JBC A;  2J17 A;  1X24 A;  3S4E A;  4KYQ A;  1PYN A;  2GP0 A;  1XRI A;  2CNG A;  4ZRT A;  3ZM2 A;  5HDE A;  2BV5 A;  3O3L A;  3BLU A;  2PI7 A;  1PXH A;  1T48 A;  1C86 A;  3SME A;  2HNP A;  5BUG A;  2NZ6 A;  3BRH A;  1KAV A;  2I3R A;  3F41 A;  4Y2E A;  1XM2 A;  5KA0 A;  3I80 A;  1P15 A;  2CNI A;  3F9A A;  2VEX A;  1V3A A;  1U25 A;  4RI5 A;  4GRY A;  3V0G A;  1OET A;  2B4O A;  1LAR A;  1GFY A;  1Q6N A;  1I9S A;  1C84 A;  2PA5 A;  3EMU A;  1OEM X;  4NWF A;  5KA8 A;  4B04 A;  1I57 A;  4JMJ A;  1JLN A;  5GTJ A;  2QBR A;  3LJ8 A;  2QCJ A;  4GFU A;  4GWF A;  3ZMQ A;  2H4G A;  4WOH A;  4WTY A;  2VEU A;  1PTY A;  2GWO A;  3QKQ A;  1KAK A;  1SUG A;  5EHP A;  4D3P A;  2AZR A;  3O5X A;  5IBS A;  3D44 A;  1FQ1 A;  3QCI A;  1YWF A;  5KA9 A;  1U24 A;  2B3O A;  2ZN7 A;  2QDM A;  2I6O A;  1WAX A;  1YPT A;  4YAA A;  4RDD A;  3S4O A;  3QCH A;  3D9C A;  3I7Z A;  4RI4 A;  1J4X A;  5BX1 A;  1OEV A;  1ECV A;  2FH7 A;  3ZM1 A;  4RH5 A;  2FJN A;  4KYR A;  3V0E A;  2BIJ A;  2HVL A;  3QCC A;  3EB1 A;  2CMA A;  1PA1 A;  2HC2 A;  2R0B A;  2QBQ A;  3SR9 A;  3RZ2 A;  2I42 A;  2PSZ A;  2QDP A;  4IKC A;  3BM8 A;  2NLK A;  2A8B A;  4ZI4 A;  1T49 A;  2I4E A;  1XXV A;  1EEO A;  1EEN A;  4OHE A;  4OHD A;  2OC3 A;  4ZN5 A;  2VEV A;  4H34 A;  2CJZ A;  2F70 A;  2I4G A;  4R0T A;  1YGU A;  2I4H A;  1R6H A;  2CM3 A;  3M4U A;  4WU2 A;  3V0D A;  3V0I A;  4MBB A;  1YZ4 A;  2CMB A;  4QBW A;  3ZM0 A;  2CFV A;  4QUN A;  3F99 A;  3AWF A;  5KAD A;  3RO1 A;  5KA3 A;  3QCB A;  2H03 A;  5KAC A;  5K22 A;  2CM7 A;  2NT2 A;  2Y2F A;  2F46 A;  2WGP A;  1NO6 A;  1C85 A;  2A3K A;  1ONY A;  2I75 A;  1OHE A;  2C7S A;  4RKK A;  2AHS A;  2H04 A;  1QXK A;  5KAA A;  1I9T A;  3V0H A;  5KA4 A;  2P4D A;  3S3K A;  1C88 A;  2F6W A;  5K9V A;  1YTW A;  3MMJ A;  2VEW A;  1A5Y A;  2CNE A;  5IBM A;  1L8G A;  1OHC A;  2HXP A;  2Q05 A;  2RF6 A;  3OLR A;  4GE5 A;  2G59 A;  1NNY A;  1ZC0 A;  3GXG A;  1WRM A;  1BZJ A;  3OMH A;  1PTU A;  1NWL A;  2HB1 A;  1Q6P A;  2H4V A;  1Q6T A;  2F71 A;  2HY3 A;  4GE6 A;  5KA2 A;  2CM8 A;  3ZM3 A;  1G7G A;  1RPM A;  1Q6J A;  2B4U A;  2VEY A;  3D1Q A;  2DXP A;  2Q47 A;  3B7O A;  1JF7 A;  4PVG A;  4GS0 A;  1U26 A;  2I5X A;  1G1G A;  2H4K A;  1LQF A;  2HC1 A;  2HCM A;  4WU3 A;  2FJM A;  3QCE A;  2G6Z A;  1G1H A;  3QCG A;  1RXD A;  2M3V A;  4S0G A;  3U96 A;  1NWE A;  1T4J A;  2C46 A;  1C87 A;  3S3H A;  1OHD A;  2CNH A;  3A5K A;  4YR8 B;  5K24 A;  5BZZ A;  4KI9 A;  2F6V A;  4JNB A;  5MMZ B;  3EAX A;  4ICZ A;  1BZH A;  2NT7 A;  2QCT A;  4AZ1 A;  3AWE A;  1M3G A;  2PBN A;  4BPC A;  3ZV2 A;  5LXQ B;  4GE2 A;  3QCN A;  5K25 A;  2BGE A;  3V0F A;  1BZC A;  4DGX A;  4ERC A;  1C83 A;  3QCM A;  2YDU A;  1L8K A;  4NWG A;  5J8R A;  2J16 B;  4HRF A;  4GRZ A;  2I6M A;  1OEO X;  3PS5 A;  1FPR A;  3O4T A;  1Q6M A;  2ZMM A;  3O4S A;  3F81 A;  4D3R A;  2F6Z A;  2MBC A;  1AAX A;  1VHR A;  2BZL A;  5I6V A;  2GJT A;  2I6P A;  2B49 A;  1PTV A;  4QBE A;  2E0T A;  1MKP A;  3AWG A;  4BJO A;  1PA9 A;  2I6J A;  1G1F A;  2OUD A;  4TVV A;  3I36 A;  4RH9 A;  4Y14 A;  2BGD A;  4Z6B A;  5K9W A;  2OZ5 A;  4DGP A;  3F9B A;  1YTN A;  2F6T A;  2QBS A;  2NTA A;  4NND A;  4NYH A;  1D5R A;  3RGQ A;  1XXP A;  1PH0 A;  5M43 A;  1YN9 A;  3MOZ A;  5EHR A;  2CNF A;  2PT0 A;  5AWX A;  2OOQ A;  1YTS A;  4QUM A;  2CMC A;  2NV5 A;  2I3U A;  3EZZ A;  4D3Q A;  1OES A;  4R30 A;  1OEU A;  4I8N A;  2F6Y A;  2H02 A;  2CM2 A;  2Y96 A;  4J51 A;  1ZZW A;  2I1Y A;  4RHG A;  2B4P A;  2B4S A;  3S3F A;  1Q1M A;  4HJP A;  2J16 A;  3V0J A;  3QCD A;  3GXH A;  3NME A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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