4KI9A

Crystal structure of the catalytic domain of human dusp12 at 2.0 a resolution
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
163
structure length
157
Chain Sequence
MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPGVEDLWRLFVPALDKPETDLLSHLDRAVAFIGQARAEGRAVLVHSHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The family-wide structure and function of human dual-specificity protein phosphatases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 12
total genus 53
structure length 157
sequence length 163
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2013-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4ki9A00
3ZM1A 3A5JA 2H4VA 1YTSA 1JF7A 3OLRA 2GJTA 2J17A 3O4TA 3QCLA 2A8BA 1GFYA 3SR9A 2VEYA 3O3LA 3N0AA 1V3AA 2QCTA 2RF6A 2BV5A 2NTAA 4OHHA 2PT0A 3A5KA 4HRFA 2OOQA 1BZHA 1OHDA 5KA0A 2YDUA 4GFUA 4JMKA 1R6HA 1Q6MA 3CM3A 1YPTA 2PI7A 1GWZA 2H4KA 1YGUA 1Q6NA 2FJMA 1PXHA 2I6JA 1PTYA 2F6WA 3BM8A 2F6YA 3V0EA 3OMHA 2Q05A 2MBCA 4BJOA 1FQ1A 2HVLA 4H34A 1M3GA 3ZV2A 2I3UA 2I3RA 3BRHA 1ONYA 2F46A 1NL9A 1NO6A 3D42A 2J16B 2I6MA 2F6FA 3QCCA 1ZCLA 2ESBA 2FJNA 2HCMA 5BZZA 1OESA 2GWOA 4I8NA 5BUGA 3EAXA 2QDMA 2VEXA 3QCGA 4Y14A 2HNQA 2VEUA 2QDCA 2CMBA 4DGXA 3AWFA 2GP0A 3BLUA 4R30A 5GTJA 2QBPA 1YGRA 2I5XA 1C84A 3B7OA 2H4GA 3F81A 3QKQA 2IMGA 4QAHA 3F99A 1NNYA 3SMEA 1WRMA 4JNBA 4J51A 4NNDA 2NV5A 1FPRA 1C86A 2FH7A 5K22A 2ZMMA 1XM2A 5K25A 1BZCA 3RGOA 3ZM3A 2CNFA 3M4UA 3O4UA 2QBQA 5IBMA 1I57A 2CJZA 1PTTA 2ZN7A 5KABA 4D3QA 5KA4A 3ZM0A 4YR8B 1YTWA 4JBCA 2BZLA 5K24A 4NYHA 3QCFA 4NWFA 4D3PA 2B49A 1U24A 2OUDA 4GWFA 2PBNA 1OETA 5HDEA 3V0FA 4ZN5A 1FPZA 2CM7A 3RO1A 2I6OA 2B4UA 2B4SA 3D44A 4KYRA 3S3EA 5KA3A 2CNEA 2F6TA 1YFOA 5KAAA 3EMUA 4ZI4A 1EEOA 2Q47A 2E0TA 4RI5A 3S3FA 4DGPA 5BZXA 3MOWA 2H02A 2P4DA 1LARA 1RPMA 3S4EA 1OHEA 3V0HA 4D3RA 2NZ6A 1YTNA 4KI9A 4R0SA 4BPCA 3QCNA 3QCBA 4NX8A 3U96A 4GE2A 4PYHA 4OHDA 3V0IA 4KYQA 2I4EA 1XXPA 2VEVA 2I42A 4WU2A 4RHGA 3AWEA 2JJDA 1C88A 1LQFA 1D5RA 5EHRA 2NT7A 1I9SA 5KA2A 5I6VA 3I80A 2QBRA 5K9VA 3F9BA 4RH5A 1PA1A 2I4HA 2QBSA 2CNGA 2VEWA 5IBSA 2PSZA 1NZ7A 3D1QA 1G1HA 5BX1A 3QCKA 3PS5A 3GXGA 2B3OA 5KADA 3V0DA 3QCIA 4OHIA 3EZZA 1OEOX 2QEPA 2BGDA 4Z6BA 4GRZA 1KAVA 3O5XA 1PH0A 2CMCA 5KA1A 3S3KA 3ZMPA 4RH9A 1PA9A 4ZRTA 1QXKA 3MOZA 1A5YA 1QZ0A 1T48A 1WAXA 1NWLA 1VHRA 1PTVA 1L8GA 4ERCA 1G4US 1OHCA 1C85A 1EENA 4PVGA 4GFVA 3I36A 4GE6A 1T4JA 1AAXA 3EB1A 5KA9A 2F71A 1XXVA 3QCEA 3ZMQA 2A3KA 2P6XA 2CM2A 5J8RA 5K23A 1SUGA 1BZJA 1C87A 1L8KA 1Q6TA 2HXPA 2OC3A 2G59A 1G1FA 2B07A 2CNIA 2Y96A 4GS0A 4NWGA 1U25A 2NLKA 2CM8A 2BIJA 4AZ1A 3AWGA 2AHSA 1MKPA 1YN9A 4QUMA 2Y2FA 4WOHA 1T49A 2HC2A 2B4PA 3S4OA 5MMZB 4OHEA 2G6ZA 2H04A 1KAKA 5AWXA 1OEMX 1X24A 5LXQB 4RDDA 4Y2EA 2F6VA 3RGQA 2AZRA 1XRIA 2H03A 1ONZA 5EHPA 3ZM2A 5M43A 4S0GA 3CWEA 1OEUA 3D9CA 4WTYA 4B04A 1JLNA 3QCJA 1G7GA 2CMAA 2PQ5A 1RXDA 2QDPA 2SHPA 3RZ2A 2R0BA 1PYNA 3D1OA 4R0TA 1YZ4A 4WU3A 2BGEA 1G7FA 1U26A 2NT2A 1YWFA 3QCDA 3QCHA 1ECVA 1WCHA 1G1GA 3LJ8A 4TVVA 4RKKA 1ZCKA 2CFVA 4IKCA 5KA7A 3D1HA 4QUNA 1NWEA 2I4GA 3QCMA 4HJQA 1I9TA 1OEVA 4QBEA 4YAAA 1C83A 4JMJA 1Q6SA 3QKPA 1Q6JA 1Q1MA 2F70A 4H1OA 3F9AA 3H2XA 4GRYA 2CNHA 4MBBA 2I1YA 2I6PA 2HB1A 3S3HA 2DXPA 5KACA 2CM3A 3V0JA 4RI4A 3GXHA 3EU0A 2J16A 3I7ZA 1G4WR 2QCJA 4OHLA 2HC1A 4GE5A 2C7SA 4QBWA 1PTUA 4HJPA 1ZZWA 2HNPA 2I75A 5K9WA 3NMEA 2PA5A 1ZC0A 2F6ZA 2C46A 3MMJA 4QAPA 1Q6PA 1XBOA 1LYVA 1P15A 3BLTA 2M3VA 3V0GA 2B4OA 5KA8A 2I6IA 1J4XA 2OZ5A 2HY3A 3O4SA 3F41A 4ICZA 2WGPA
chains in the Genus database with same CATH superfamily
3ZM1A 3A5JA 2H4VA 1YTSA 1JF7A 3OLRA 2GJTA 2J17A 3O4TA 2AM2A 3QCLA 2A8BA 1GFYA 3SR9A 2VEYA 3O3LA 3N0AA 1V3AA 2QCTA 2RF6A 2VTEA 2BV5A 2NTAA 4OHHA 2PT0A 3A5KA 4HRFA 2OOQA 1BZHA 1OHDA 5KA0A 2YDUA 4GFUA 4JMKA 1R6HA 1Q6MA 3CM3A 1YPTA 2PI7A 1GWZA 2H4KA 1YGUA 1Q6NA 2FJMA 1PXHA 2I6JA 2JFFA 1PTYA 2F6WA 3BM8A 2F6YA 3V0EA 3OMHA 2Q05A 2MBCA 4BJOA 1FQ1A 2HVLA 4H34A 1M3GA 3ZV2A 2I3UA 2I3RA 3BRHA 1ONYA 2F46A 1NL9A 1GG4A 1NO6A 3D42A 2J16B 2I6MA 4ZIYA 2F6FA 3QCCA 1GQYA 1ZCLA 2ESBA 2FJNA 2HCMA 5BZZA 1OESA 2GWOA 2GC5A 4I8NA 5BUGA 3EAXA 1JBVA 2QDMA 2VEXA 4UAGA 4CVMA 3QCGA 2GCAA 3NRSA 4Y14A 2HNQA 2VEUA 2QDCA 2CMBA 4DGXA 3AWFA 2GP0A 3BLUA 3UAGA 4R30A 5GTJA 2QBPA 2WTZA 1YGRA 2I5XA 1C84A 3B7OA 2H4GA 3F81A 3QKQA 2IMGA 4QAHA 3F99A 1NNYA 3SMEA 1WRMA 4JNBA 3N2AA 4J51A 4NNDA 2NV5A 1FPRA 2Y68A 1C86A 2FH7A 5K22A 2ZMMA 1XM2A 5K25A 1BZCA 3RGOA 3ZM3A 2CNFA 3M4UA 4HV4A 3O4UA 2QBQA 3ZL8A 1I57A 2CJZA 1PTTA 5IBMA 1FGSA 2ZN7A 5KABA 4D3QA 3ZM6A 5KA4A 3ZM0A 4YR8B 1YTWA 4JBCA 2BZLA 5K24A 4NYHA 3QCFA 4NWFA 4D3PA 2B49A 1U24A 2OUDA 4GWFA 2PBNA 1OETA 5HDEA 3V0FA 4ZN5A 1FPZA 2CM7A 4C12A 3RO1A 1W78A 1P31A 3PYZA 2VORA 2I6OA 2B4UA 2B4SA 3D44A 4KYRA 3S3EA 3QCZA 2CNEA 5KA3A 2F6TA 1YFOA 5KAAA 3EMUA 2AM1A 4ZI4A 1EEOA 2Y66A 2Q47A 1UAGA 2E0TA 4RI5A 3S3FA 1O5ZA 4DGPA 2Y67A 1J6UA 3MOWA 2H02A 2P4DA 1LARA 1RPMA 5BZXA 1OHEA 3S4EA 3V0HA 4BUBA 4D3RA 2NZ6A 1YTNA 4KI9A 4R0SA 1E0DA 4BPCA 3QCNA 3QCBA 4NX8A 3U96A 4GE2A 4PYHA 4OHDA 3V0IA 4KYQA 2I4EA 1XXPA 2VEVA 2I42A 4WU2A 4RHGA 3AWEA 2JJDA 1C88A 1LQFA 1D5RA 5EHRA 2NT7A 1I9SA 2WJPA 5KA2A 5I6VA 3I80A 2JFGA 2QBRA 3HN7A 5K9VA 3F9BA 1JBWA 4RH5A 1PA1A 2I4HA 2QBSA 2CNGA 2VEWA 2VOSA 5IBSA 2PSZA 1NZ7A 3D1QA 1G1HA 5BX1A 3QCKA 3PS5A 1EEHA 3GXGA 2B3OA 5KADA 3V0DA 3QCIA 2XPCA 4OHIA 3EZZA 1OEOX 2QEPA 2BGDA 4Z6BA 4GRZA 1KAVA 3O5XA 1PH0A 2CMCA 3MVNA 5KA1A 3S3KA 3ZMPA 4RH9A 1PA9A 4ZRTA 1QXKA 2JFHA 3MOZA 5A5FA 1A5YA 1QZ0A 1T48A 1WAXA 1NWLA 1VHRA 2UUOA 1PTVA 1L8GA 4ERCA 1G4US 1OHCA 1C85A 4CVLA 1EENA 4PVGA 4GFVA 3I36A 4GE6A 1T4JA 1AAXA 3EB1A 5KA9A 2F71A 1XXVA 3QCEA 3ZMQA 2A3KA 2XJAA 2UUPA 2P6XA 2CM2A 5J8RA 5K23A 1SUGA 1BZJA 1C87A 1L8KA 1Q6TA 2HXPA 2OC3A 2G59A 1G1FA 2Y1OA 2B07A 2CNIA 2Y96A 4GS0A 4NWGA 1U25A 2NLKA 1W7KA 5A5EA 2CM8A 2BIJA 4AZ1A 3AWGA 2AHSA 1MKPA 1YN9A 4QUMA 2Y2FA 4WOHA 1T49A 2HC2A 2B4PA 3S4OA 5MMZB 4OHEA 2G6ZA 1GQQA 2H04A 1KAKA 5AWXA 1OEMX 1X24A 5LXQB 4RDDA 4Y2EA 2F6VA 3RGQA 2AZRA 1XRIA 1P3DA 2H03A 1ONZA 5EHPA 3ZM2A 5M43A 4S0GA 3CWEA 1OEUA 3D9CA 4WTYA 4B04A 1JLNA 3QCJA 1G7GA 2VTDA 2CMAA 2PQ5A 1RXDA 4QF5A 2QDPA 2SHPA 3RZ2A 2R0BA 1PYNA 3D1OA 2GC6A 4R0TA 1YZ4A 4WU3A 2BGEA 1G7FA 1U26A 2NT2A 1YWFA 3QCDA 3QCHA 4QDIA 1ECVA 1WCHA 1G1GA 3LJ8A 4TVVA 4RKKA 1ZCKA 2CFVA 4IKCA 5KA7A 3D1HA 4QUNA 1NWEA 4CVKA 2I4GA 3QCMA 4HJQA 1I9TA 1OEVA 4QBEA 4YAAA 2X5OA 1C83A 3LK7A 4JMJA 1Q6SA 3QKPA 1Q6JA 1Q1MA 2F70A 4H1OA 3F9AA 3H2XA 4GRYA 3ZM5A 1E8CA 2CNHA 4BUCA 4MBBA 2I1YA 2I6PA 2HB1A 3S3HA 2DXPA 5KACA 2CM3A 3V0JA 4RI4A 3GXHA 3EU0A 2J16A 3I7ZA 1G4WR 2QCJA 4OHLA 2HC1A 2F00A 4GE5A 2C7SA 4QBWA 1PTUA 4C13A 4HJPA 1ZZWA 2HNPA 2UAGA 2I75A 5K9WA 3NMEA 2PA5A 1ZC0A 2F6ZA 2C46A 3MMJA 4QAPA 1Q6PA 1XBOA 1LYVA 1P15A 3BLTA 2M3VA 2GCBA 3V0GA 2B4OA 5KA8A 2I6IA 1J4XA 2OZ5A 2HY3A 3O4SA 3F41A 4ICZA 2WGPA
chains in the Genus database with same CATH topology
3ZM1A 3A5JA 2H4VA 1YTSA 1JF7A 3OLRA 2GJTA 2J17A 3O4TA 3QCLA 2A8BA 1GFYA 3SR9A 2VEYA 3O3LA 3N0AA 1V3AA 2QCTA 2RF6A 2BV5A 2NTAA 4OHHA 2PT0A 3A5KA 4HRFA 2OOQA 1BZHA 1OHDA 5KA0A 2YDUA 4GFUA 4JMKA 1R6HA 1Q6MA 3CM3A 1YPTA 2PI7A 1GWZA 2H4KA 1YGUA 1Q6NA 2FJMA 1PXHA 2I6JA 1PTYA 2F6WA 3BM8A 2F6YA 3V0EA 3OMHA 2Q05A 2MBCA 4BJOA 1FQ1A 2HVLA 4H34A 1M3GA 3ZV2A 2I3UA 2I3RA 3BRHA 1ONYA 2F46A 1NL9A 1NO6A 3D42A 2J16B 2I6MA 2F6FA 3QCCA 1ZCLA 2ESBA 2FJNA 2HCMA 5BZZA 1OESA 2GWOA 4I8NA 5BUGA 3EAXA 2QDMA 2VEXA 3QCGA 4Y14A 2HNQA 2VEUA 2QDCA 2CMBA 4DGXA 3AWFA 2GP0A 3BLUA 4R30A 5GTJA 2QBPA 1YGRA 2I5XA 1C84A 3B7OA 2H4GA 3F81A 3QKQA 2IMGA 4QAHA 3F99A 1NNYA 3SMEA 1WRMA 4JNBA 4J51A 4NNDA 2NV5A 1FPRA 1C86A 2FH7A 5K22A 2ZMMA 1XM2A 5K25A 1BZCA 3RGOA 3ZM3A 2CNFA 3M4UA 3O4UA 2QBQA 5IBMA 1I57A 2CJZA 1PTTA 2ZN7A 5KABA 4D3QA 5KA4A 3ZM0A 4YR8B 1YTWA 4JBCA 2BZLA 5K24A 4NYHA 3QCFA 4NWFA 4D3PA 2B49A 1U24A 2OUDA 4GWFA 2PBNA 1OETA 5HDEA 3V0FA 4ZN5A 1FPZA 2CM7A 3RO1A 2I6OA 2B4UA 2B4SA 3D44A 4KYRA 3S3EA 5KA3A 2CNEA 2F6TA 1YFOA 5KAAA 3EMUA 4ZI4A 1EEOA 2Q47A 2E0TA 4RI5A 3S3FA 4DGPA 5BZXA 3MOWA 2H02A 2P4DA 1LARA 1RPMA 3S4EA 1OHEA 3V0HA 4D3RA 2NZ6A 1YTNA 4KI9A 4R0SA 4BPCA 3QCNA 3QCBA 4NX8A 3U96A 4GE2A 4PYHA 4OHDA 3V0IA 4KYQA 2I4EA 1XXPA 2VEVA 2I42A 4WU2A 4RHGA 3AWEA 2JJDA 1C88A 1LQFA 1D5RA 5EHRA 2NT7A 1I9SA 5KA2A 5I6VA 3I80A 2QBRA 5K9VA 3F9BA 4RH5A 1PA1A 2I4HA 2QBSA 2CNGA 2VEWA 5IBSA 2PSZA 1NZ7A 3D1QA 1G1HA 5BX1A 3QCKA 3PS5A 3GXGA 2B3OA 5KADA 3V0DA 3QCIA 4OHIA 3EZZA 1OEOX 2QEPA 2BGDA 4Z6BA 4GRZA 1KAVA 3O5XA 1PH0A 2CMCA 5KA1A 3S3KA 3ZMPA 4RH9A 1PA9A 4ZRTA 1QXKA 3MOZA 1A5YA 1QZ0A 1T48A 1WAXA 1NWLA 1VHRA 1PTVA 1L8GA 4ERCA 1G4US 1OHCA 1C85A 1EENA 4PVGA 4GFVA 3I36A 4GE6A 1T4JA 1AAXA 3EB1A 5KA9A 2F71A 1XXVA 3QCEA 3ZMQA 2A3KA 2P6XA 2CM2A 5J8RA 5K23A 1SUGA 1BZJA 1C87A 1L8KA 1Q6TA 2HXPA 2OC3A 2G59A 1G1FA 2B07A 2CNIA 2Y96A 4GS0A 4NWGA 1U25A 2NLKA 2CM8A 2BIJA 4AZ1A 3AWGA 2AHSA 1MKPA 1YN9A 4QUMA 2Y2FA 4WOHA 1T49A 2HC2A 2B4PA 3S4OA 5MMZB 4OHEA 2G6ZA 2H04A 1KAKA 5AWXA 1OEMX 1X24A 5LXQB 4RDDA 4Y2EA 2F6VA 3RGQA 2AZRA 1XRIA 2H03A 1ONZA 5EHPA 3ZM2A 5M43A 4S0GA 3CWEA 1OEUA 3D9CA 4WTYA 4B04A 1JLNA 3QCJA 1G7GA 2CMAA 2PQ5A 1RXDA 2QDPA 2SHPA 3RZ2A 2R0BA 1PYNA 3D1OA 4R0TA 1YZ4A 4WU3A 2BGEA 1G7FA 1U26A 2NT2A 1YWFA 3QCDA 3QCHA 1ECVA 1WCHA 1G1GA 3LJ8A 4TVVA 4RKKA 1ZCKA 2CFVA 4IKCA 5KA7A 3D1HA 4QUNA 1NWEA 2I4GA 3QCMA 4HJQA 1I9TA 1OEVA 4QBEA 4YAAA 1C83A 4JMJA 1Q6SA 3QKPA 1Q6JA 1Q1MA 2F70A 4H1OA 3F9AA 3H2XA 4GRYA 2CNHA 4MBBA 2I1YA 2I6PA 2HB1A 3S3HA 2DXPA 5KACA 2CM3A 3V0JA 4RI4A 3GXHA 3EU0A 2J16A 3I7ZA 1G4WR 2QCJA 4OHLA 2HC1A 4GE5A 2C7SA 4QBWA 1PTUA 4HJPA 1ZZWA 2HNPA 2I75A 5K9WA 3NMEA 2PA5A 1ZC0A 2F6ZA 2C46A 3MMJA 4QAPA 1Q6PA 1XBOA 1LYVA 1P15A 3BLTA 2M3VA 3V0GA 2B4OA 5KA8A 2I6IA 1J4XA 2OZ5A 2HY3A 3O4SA 3F41A 4ICZA 2WGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZM1 A;  3A5J A;  2H4V A;  1YTS A;  1JF7 A;  3OLR A;  2GJT A;  2J17 A;  3O4T A;  3QCL A;  2A8B A;  1GFY A;  3SR9 A;  2VEY A;  3O3L A;  3N0A A;  1V3A A;  2QCT A;  2RF6 A;  2BV5 A;  2NTA A;  4OHH A;  2PT0 A;  3A5K A;  4HRF A;  2OOQ A;  1BZH A;  1OHD A;  5KA0 A;  2YDU A;  4GFU A;  4JMK A;  1R6H A;  1Q6M A;  3CM3 A;  1YPT A;  2PI7 A;  1GWZ A;  2H4K A;  1YGU A;  1Q6N A;  2FJM A;  1PXH A;  2I6J A;  1PTY A;  2F6W A;  3BM8 A;  2F6Y A;  3V0E A;  3OMH A;  2Q05 A;  2MBC A;  4BJO A;  1FQ1 A;  2HVL A;  4H34 A;  1M3G A;  3ZV2 A;  2I3U A;  2I3R A;  3BRH A;  1ONY A;  2F46 A;  1NL9 A;  1NO6 A;  3D42 A;  2J16 B;  2I6M A;  2F6F A;  3QCC A;  1ZCL A;  2ESB A;  2FJN A;  2HCM A;  5BZZ A;  1OES A;  2GWO A;  4I8N A;  5BUG A;  3EAX A;  2QDM A;  2VEX A;  3QCG A;  4Y14 A;  2HNQ A;  2VEU A;  2QDC A;  2CMB A;  4DGX A;  3AWF A;  2GP0 A;  3BLU A;  4R30 A;  5GTJ A;  2QBP A;  1YGR A;  2I5X A;  1C84 A;  3B7O A;  2H4G A;  3F81 A;  3QKQ A;  2IMG A;  4QAH A;  3F99 A;  1NNY A;  3SME A;  1WRM A;  4JNB A;  4J51 A;  4NND A;  2NV5 A;  1FPR A;  1C86 A;  2FH7 A;  5K22 A;  2ZMM A;  1XM2 A;  5K25 A;  1BZC A;  3RGO A;  3ZM3 A;  2CNF A;  3M4U A;  3O4U A;  2QBQ A;  5IBM A;  1I57 A;  2CJZ A;  1PTT A;  2ZN7 A;  5KAB A;  4D3Q A;  5KA4 A;  3ZM0 A;  4YR8 B;  1YTW A;  4JBC A;  2BZL A;  5K24 A;  4NYH A;  3QCF A;  4NWF A;  4D3P A;  2B49 A;  1U24 A;  2OUD A;  4GWF A;  2PBN A;  1OET A;  5HDE A;  3V0F A;  4ZN5 A;  1FPZ A;  2CM7 A;  3RO1 A;  2I6O A;  2B4U A;  2B4S A;  3D44 A;  4KYR A;  3S3E A;  5KA3 A;  2CNE A;  2F6T A;  1YFO A;  5KAA A;  3EMU A;  4ZI4 A;  1EEO A;  2Q47 A;  2E0T A;  4RI5 A;  3S3F A;  4DGP A;  5BZX A;  3MOW A;  2H02 A;  2P4D A;  1LAR A;  1RPM A;  3S4E A;  1OHE A;  3V0H A;  4D3R A;  2NZ6 A;  1YTN A;  4KI9 A;  4R0S A;  4BPC A;  3QCN A;  3QCB A;  4NX8 A;  3U96 A;  4GE2 A;  4PYH A;  4OHD A;  3V0I A;  4KYQ A;  2I4E A;  1XXP A;  2VEV A;  2I42 A;  4WU2 A;  4RHG A;  3AWE A;  2JJD A;  1C88 A;  1LQF A;  1D5R A;  5EHR A;  2NT7 A;  1I9S A;  5KA2 A;  5I6V A;  3I80 A;  2QBR A;  5K9V A;  3F9B A;  4RH5 A;  1PA1 A;  2I4H A;  2QBS A;  2CNG A;  2VEW A;  5IBS A;  2PSZ A;  1NZ7 A;  3D1Q A;  1G1H A;  5BX1 A;  3QCK A;  3PS5 A;  3GXG A;  2B3O A;  5KAD A;  3V0D A;  3QCI A;  4OHI A;  3EZZ A;  1OEO X;  2QEP A;  2BGD A;  4Z6B A;  4GRZ A;  1KAV A;  3O5X A;  1PH0 A;  2CMC A;  5KA1 A;  3S3K A;  3ZMP A;  4RH9 A;  1PA9 A;  4ZRT A;  1QXK A;  3MOZ A;  1A5Y A;  1QZ0 A;  1T48 A;  1WAX A;  1NWL A;  1VHR A;  1PTV A;  1L8G A;  4ERC A;  1G4U S;  1OHC A;  1C85 A;  1EEN A;  4PVG A;  4GFV A;  3I36 A;  4GE6 A;  1T4J A;  1AAX A;  3EB1 A;  5KA9 A;  2F71 A;  1XXV A;  3QCE A;  3ZMQ A;  2A3K A;  2P6X A;  2CM2 A;  5J8R A;  5K23 A;  1SUG A;  1BZJ A;  1C87 A;  1L8K A;  1Q6T A;  2HXP A;  2OC3 A;  2G59 A;  1G1F A;  2B07 A;  2CNI A;  2Y96 A;  4GS0 A;  4NWG A;  1U25 A;  2NLK A;  2CM8 A;  2BIJ A;  4AZ1 A;  3AWG A;  2AHS A;  1MKP A;  1YN9 A;  4QUM A;  2Y2F A;  4WOH A;  1T49 A;  2HC2 A;  2B4P A;  3S4O A;  5MMZ B;  4OHE A;  2G6Z A;  2H04 A;  1KAK A;  5AWX A;  1OEM X;  1X24 A;  5LXQ B;  4RDD A;  4Y2E A;  2F6V A;  3RGQ A;  2AZR A;  1XRI A;  2H03 A;  1ONZ A;  5EHP A;  3ZM2 A;  5M43 A;  4S0G A;  3CWE A;  1OEU A;  3D9C A;  4WTY A;  4B04 A;  1JLN A;  3QCJ A;  1G7G A;  2CMA A;  2PQ5 A;  1RXD A;  2QDP A;  2SHP A;  3RZ2 A;  2R0B A;  1PYN A;  3D1O A;  4R0T A;  1YZ4 A;  4WU3 A;  2BGE A;  1G7F A;  1U26 A;  2NT2 A;  1YWF A;  3QCD A;  3QCH A;  1ECV A;  1WCH A;  1G1G A;  3LJ8 A;  4TVV A;  4RKK A;  1ZCK A;  2CFV A;  4IKC A;  5KA7 A;  3D1H A;  4QUN A;  1NWE A;  2I4G A;  3QCM A;  4HJQ A;  1I9T A;  1OEV A;  4QBE A;  4YAA A;  1C83 A;  4JMJ A;  1Q6S A;  3QKP A;  1Q6J A;  1Q1M A;  2F70 A;  4H1O A;  3F9A A;  3H2X A;  4GRY A;  2CNH A;  4MBB A;  2I1Y A;  2I6P A;  2HB1 A;  3S3H A;  2DXP A;  5KAC A;  2CM3 A;  3V0J A;  4RI4 A;  3GXH A;  3EU0 A;  2J16 A;  3I7Z A;  1G4W R;  2QCJ A;  4OHL A;  2HC1 A;  4GE5 A;  2C7S A;  4QBW A;  1PTU A;  4HJP A;  1ZZW A;  2HNP A;  2I75 A;  5K9W A;  3NME A;  2PA5 A;  1ZC0 A;  2F6Z A;  2C46 A;  3MMJ A;  4QAP A;  1Q6P A;  1XBO A;  1LYV A;  1P15 A;  3BLT A;  2M3V A;  3V0G A;  2B4O A;  5KA8 A;  2I6I A;  1J4X A;  2OZ5 A;  2HY3 A;  3O4S A;  3F41 A;  4ICZ A;  2WGP A; 
#chains in the Genus database with same CATH topology
 3ZM1 A;  3A5J A;  2H4V A;  1YTS A;  1JF7 A;  3OLR A;  2GJT A;  2J17 A;  3O4T A;  2AM2 A;  3QCL A;  2A8B A;  1GFY A;  3SR9 A;  2VEY A;  3O3L A;  3N0A A;  1V3A A;  2QCT A;  2RF6 A;  2VTE A;  2BV5 A;  2NTA A;  4OHH A;  2PT0 A;  3A5K A;  4HRF A;  2OOQ A;  1BZH A;  1OHD A;  5KA0 A;  2YDU A;  4GFU A;  4JMK A;  1R6H A;  1Q6M A;  3CM3 A;  1YPT A;  2PI7 A;  1GWZ A;  2H4K A;  1YGU A;  1Q6N A;  2FJM A;  1PXH A;  2I6J A;  2JFF A;  1PTY A;  2F6W A;  3BM8 A;  2F6Y A;  3V0E A;  3OMH A;  2Q05 A;  2MBC A;  4BJO A;  1FQ1 A;  2HVL A;  4H34 A;  1M3G A;  3ZV2 A;  2I3U A;  2I3R A;  3BRH A;  1ONY A;  2F46 A;  1NL9 A;  1GG4 A;  1NO6 A;  3D42 A;  2J16 B;  2I6M A;  4ZIY A;  2F6F A;  3QCC A;  1GQY A;  1ZCL A;  2ESB A;  2FJN A;  2HCM A;  5BZZ A;  1OES A;  2GWO A;  2GC5 A;  4I8N A;  5BUG A;  3EAX A;  1JBV A;  2QDM A;  2VEX A;  4UAG A;  4CVM A;  3QCG A;  2GCA A;  3NRS A;  4Y14 A;  2HNQ A;  2VEU A;  2QDC A;  2CMB A;  4DGX A;  3AWF A;  2GP0 A;  3BLU A;  3UAG A;  4R30 A;  5GTJ A;  2QBP A;  2WTZ A;  1YGR A;  2I5X A;  1C84 A;  3B7O A;  2H4G A;  3F81 A;  3QKQ A;  2IMG A;  4QAH A;  3F99 A;  1NNY A;  3SME A;  1WRM A;  4JNB A;  3N2A A;  4J51 A;  4NND A;  2NV5 A;  1FPR A;  2Y68 A;  1C86 A;  2FH7 A;  5K22 A;  2ZMM A;  1XM2 A;  5K25 A;  1BZC A;  3RGO A;  3ZM3 A;  2CNF A;  3M4U A;  4HV4 A;  3O4U A;  2QBQ A;  3ZL8 A;  1I57 A;  2CJZ A;  1PTT A;  5IBM A;  1FGS A;  2ZN7 A;  5KAB A;  4D3Q A;  3ZM6 A;  5KA4 A;  3ZM0 A;  4YR8 B;  1YTW A;  4JBC A;  2BZL A;  5K24 A;  4NYH A;  3QCF A;  4NWF A;  4D3P A;  2B49 A;  1U24 A;  2OUD A;  4GWF A;  2PBN A;  1OET A;  5HDE A;  3V0F A;  4ZN5 A;  1FPZ A;  2CM7 A;  4C12 A;  3RO1 A;  1W78 A;  1P31 A;  3PYZ A;  2VOR A;  2I6O A;  2B4U A;  2B4S A;  3D44 A;  4KYR A;  3S3E A;  3QCZ A;  2CNE A;  5KA3 A;  2F6T A;  1YFO A;  5KAA A;  3EMU A;  2AM1 A;  4ZI4 A;  1EEO A;  2Y66 A;  2Q47 A;  1UAG A;  2E0T A;  4RI5 A;  3S3F A;  1O5Z A;  4DGP A;  2Y67 A;  1J6U A;  3MOW A;  2H02 A;  2P4D A;  1LAR A;  1RPM A;  5BZX A;  1OHE A;  3S4E A;  3V0H A;  4BUB A;  4D3R A;  2NZ6 A;  1YTN A;  4KI9 A;  4R0S A;  1E0D A;  4BPC A;  3QCN A;  3QCB A;  4NX8 A;  3U96 A;  4GE2 A;  4PYH A;  4OHD A;  3V0I A;  4KYQ A;  2I4E A;  1XXP A;  2VEV A;  2I42 A;  4WU2 A;  4RHG A;  3AWE A;  2JJD A;  1C88 A;  1LQF A;  1D5R A;  5EHR A;  2NT7 A;  1I9S A;  2WJP A;  5KA2 A;  5I6V A;  3I80 A;  2JFG A;  2QBR A;  3HN7 A;  5K9V A;  3F9B A;  1JBW A;  4RH5 A;  1PA1 A;  2I4H A;  2QBS A;  2CNG A;  2VEW A;  2VOS A;  5IBS A;  2PSZ A;  1NZ7 A;  3D1Q A;  1G1H A;  5BX1 A;  3QCK A;  3PS5 A;  1EEH A;  3GXG A;  2B3O A;  5KAD A;  3V0D A;  3QCI A;  2XPC A;  4OHI A;  3EZZ A;  1OEO X;  2QEP A;  2BGD A;  4Z6B A;  4GRZ A;  1KAV A;  3O5X A;  1PH0 A;  2CMC A;  3MVN A;  5KA1 A;  3S3K A;  3ZMP A;  4RH9 A;  1PA9 A;  4ZRT A;  1QXK A;  2JFH A;  3MOZ A;  5A5F A;  1A5Y A;  1QZ0 A;  1T48 A;  1WAX A;  1NWL A;  1VHR A;  2UUO A;  1PTV A;  1L8G A;  4ERC A;  1G4U S;  1OHC A;  1C85 A;  4CVL A;  1EEN A;  4PVG A;  4GFV A;  3I36 A;  4GE6 A;  1T4J A;  1AAX A;  3EB1 A;  5KA9 A;  2F71 A;  1XXV A;  3QCE A;  3ZMQ A;  2A3K A;  2XJA A;  2UUP A;  2P6X A;  2CM2 A;  5J8R A;  5K23 A;  1SUG A;  1BZJ A;  1C87 A;  1L8K A;  1Q6T A;  2HXP A;  2OC3 A;  2G59 A;  1G1F A;  2Y1O A;  2B07 A;  2CNI A;  2Y96 A;  4GS0 A;  4NWG A;  1U25 A;  2NLK A;  1W7K A;  5A5E A;  2CM8 A;  2BIJ A;  4AZ1 A;  3AWG A;  2AHS A;  1MKP A;  1YN9 A;  4QUM A;  2Y2F A;  4WOH A;  1T49 A;  2HC2 A;  2B4P A;  3S4O A;  5MMZ B;  4OHE A;  2G6Z A;  1GQQ A;  2H04 A;  1KAK A;  5AWX A;  1OEM X;  1X24 A;  5LXQ B;  4RDD A;  4Y2E A;  2F6V A;  3RGQ A;  2AZR A;  1XRI A;  1P3D A;  2H03 A;  1ONZ A;  5EHP A;  3ZM2 A;  5M43 A;  4S0G A;  3CWE A;  1OEU A;  3D9C A;  4WTY A;  4B04 A;  1JLN A;  3QCJ A;  1G7G A;  2VTD A;  2CMA A;  2PQ5 A;  1RXD A;  4QF5 A;  2QDP A;  2SHP A;  3RZ2 A;  2R0B A;  1PYN A;  3D1O A;  2GC6 A;  4R0T A;  1YZ4 A;  4WU3 A;  2BGE A;  1G7F A;  1U26 A;  2NT2 A;  1YWF A;  3QCD A;  3QCH A;  4QDI A;  1ECV A;  1WCH A;  1G1G A;  3LJ8 A;  4TVV A;  4RKK A;  1ZCK A;  2CFV A;  4IKC A;  5KA7 A;  3D1H A;  4QUN A;  1NWE A;  4CVK A;  2I4G A;  3QCM A;  4HJQ A;  1I9T A;  1OEV A;  4QBE A;  4YAA A;  2X5O A;  1C83 A;  3LK7 A;  4JMJ A;  1Q6S A;  3QKP A;  1Q6J A;  1Q1M A;  2F70 A;  4H1O A;  3F9A A;  3H2X A;  4GRY A;  3ZM5 A;  1E8C A;  2CNH A;  4BUC A;  4MBB A;  2I1Y A;  2I6P A;  2HB1 A;  3S3H A;  2DXP A;  5KAC A;  2CM3 A;  3V0J A;  4RI4 A;  3GXH A;  3EU0 A;  2J16 A;  3I7Z A;  1G4W R;  2QCJ A;  4OHL A;  2HC1 A;  2F00 A;  4GE5 A;  2C7S A;  4QBW A;  1PTU A;  4C13 A;  4HJP A;  1ZZW A;  2HNP A;  2UAG A;  2I75 A;  5K9W A;  3NME A;  2PA5 A;  1ZC0 A;  2F6Z A;  2C46 A;  3MMJ A;  4QAP A;  1Q6P A;  1XBO A;  1LYV A;  1P15 A;  3BLT A;  2M3V A;  2GCB A;  3V0G A;  2B4O A;  5KA8 A;  2I6I A;  1J4X A;  2OZ5 A;  2HY3 A;  3O4S A;  3F41 A;  4ICZ A;  2WGP A; 
#chains in the Genus database with same CATH homology
 3ZM1 A;  3A5J A;  2H4V A;  1YTS A;  1JF7 A;  3OLR A;  2GJT A;  2J17 A;  3O4T A;  3QCL A;  2A8B A;  1GFY A;  3SR9 A;  2VEY A;  3O3L A;  3N0A A;  1V3A A;  2QCT A;  2RF6 A;  2BV5 A;  2NTA A;  4OHH A;  2PT0 A;  3A5K A;  4HRF A;  2OOQ A;  1BZH A;  1OHD A;  5KA0 A;  2YDU A;  4GFU A;  4JMK A;  1R6H A;  1Q6M A;  3CM3 A;  1YPT A;  2PI7 A;  1GWZ A;  2H4K A;  1YGU A;  1Q6N A;  2FJM A;  1PXH A;  2I6J A;  1PTY A;  2F6W A;  3BM8 A;  2F6Y A;  3V0E A;  3OMH A;  2Q05 A;  2MBC A;  4BJO A;  1FQ1 A;  2HVL A;  4H34 A;  1M3G A;  3ZV2 A;  2I3U A;  2I3R A;  3BRH A;  1ONY A;  2F46 A;  1NL9 A;  1NO6 A;  3D42 A;  2J16 B;  2I6M A;  2F6F A;  3QCC A;  1ZCL A;  2ESB A;  2FJN A;  2HCM A;  5BZZ A;  1OES A;  2GWO A;  4I8N A;  5BUG A;  3EAX A;  2QDM A;  2VEX A;  3QCG A;  4Y14 A;  2HNQ A;  2VEU A;  2QDC A;  2CMB A;  4DGX A;  3AWF A;  2GP0 A;  3BLU A;  4R30 A;  5GTJ A;  2QBP A;  1YGR A;  2I5X A;  1C84 A;  3B7O A;  2H4G A;  3F81 A;  3QKQ A;  2IMG A;  4QAH A;  3F99 A;  1NNY A;  3SME A;  1WRM A;  4JNB A;  4J51 A;  4NND A;  2NV5 A;  1FPR A;  1C86 A;  2FH7 A;  5K22 A;  2ZMM A;  1XM2 A;  5K25 A;  1BZC A;  3RGO A;  3ZM3 A;  2CNF A;  3M4U A;  3O4U A;  2QBQ A;  5IBM A;  1I57 A;  2CJZ A;  1PTT A;  2ZN7 A;  5KAB A;  4D3Q A;  5KA4 A;  3ZM0 A;  4YR8 B;  1YTW A;  4JBC A;  2BZL A;  5K24 A;  4NYH A;  3QCF A;  4NWF A;  4D3P A;  2B49 A;  1U24 A;  2OUD A;  4GWF A;  2PBN A;  1OET A;  5HDE A;  3V0F A;  4ZN5 A;  1FPZ A;  2CM7 A;  3RO1 A;  2I6O A;  2B4U A;  2B4S A;  3D44 A;  4KYR A;  3S3E A;  5KA3 A;  2CNE A;  2F6T A;  1YFO A;  5KAA A;  3EMU A;  4ZI4 A;  1EEO A;  2Q47 A;  2E0T A;  4RI5 A;  3S3F A;  4DGP A;  5BZX A;  3MOW A;  2H02 A;  2P4D A;  1LAR A;  1RPM A;  3S4E A;  1OHE A;  3V0H A;  4D3R A;  2NZ6 A;  1YTN A;  4KI9 A;  4R0S A;  4BPC A;  3QCN A;  3QCB A;  4NX8 A;  3U96 A;  4GE2 A;  4PYH A;  4OHD A;  3V0I A;  4KYQ A;  2I4E A;  1XXP A;  2VEV A;  2I42 A;  4WU2 A;  4RHG A;  3AWE A;  2JJD A;  1C88 A;  1LQF A;  1D5R A;  5EHR A;  2NT7 A;  1I9S A;  5KA2 A;  5I6V A;  3I80 A;  2QBR A;  5K9V A;  3F9B A;  4RH5 A;  1PA1 A;  2I4H A;  2QBS A;  2CNG A;  2VEW A;  5IBS A;  2PSZ A;  1NZ7 A;  3D1Q A;  1G1H A;  5BX1 A;  3QCK A;  3PS5 A;  3GXG A;  2B3O A;  5KAD A;  3V0D A;  3QCI A;  4OHI A;  3EZZ A;  1OEO X;  2QEP A;  2BGD A;  4Z6B A;  4GRZ A;  1KAV A;  3O5X A;  1PH0 A;  2CMC A;  5KA1 A;  3S3K A;  3ZMP A;  4RH9 A;  1PA9 A;  4ZRT A;  1QXK A;  3MOZ A;  1A5Y A;  1QZ0 A;  1T48 A;  1WAX A;  1NWL A;  1VHR A;  1PTV A;  1L8G A;  4ERC A;  1G4U S;  1OHC A;  1C85 A;  1EEN A;  4PVG A;  4GFV A;  3I36 A;  4GE6 A;  1T4J A;  1AAX A;  3EB1 A;  5KA9 A;  2F71 A;  1XXV A;  3QCE A;  3ZMQ A;  2A3K A;  2P6X A;  2CM2 A;  5J8R A;  5K23 A;  1SUG A;  1BZJ A;  1C87 A;  1L8K A;  1Q6T A;  2HXP A;  2OC3 A;  2G59 A;  1G1F A;  2B07 A;  2CNI A;  2Y96 A;  4GS0 A;  4NWG A;  1U25 A;  2NLK A;  2CM8 A;  2BIJ A;  4AZ1 A;  3AWG A;  2AHS A;  1MKP A;  1YN9 A;  4QUM A;  2Y2F A;  4WOH A;  1T49 A;  2HC2 A;  2B4P A;  3S4O A;  5MMZ B;  4OHE A;  2G6Z A;  2H04 A;  1KAK A;  5AWX A;  1OEM X;  1X24 A;  5LXQ B;  4RDD A;  4Y2E A;  2F6V A;  3RGQ A;  2AZR A;  1XRI A;  2H03 A;  1ONZ A;  5EHP A;  3ZM2 A;  5M43 A;  4S0G A;  3CWE A;  1OEU A;  3D9C A;  4WTY A;  4B04 A;  1JLN A;  3QCJ A;  1G7G A;  2CMA A;  2PQ5 A;  1RXD A;  2QDP A;  2SHP A;  3RZ2 A;  2R0B A;  1PYN A;  3D1O A;  4R0T A;  1YZ4 A;  4WU3 A;  2BGE A;  1G7F A;  1U26 A;  2NT2 A;  1YWF A;  3QCD A;  3QCH A;  1ECV A;  1WCH A;  1G1G A;  3LJ8 A;  4TVV A;  4RKK A;  1ZCK A;  2CFV A;  4IKC A;  5KA7 A;  3D1H A;  4QUN A;  1NWE A;  2I4G A;  3QCM A;  4HJQ A;  1I9T A;  1OEV A;  4QBE A;  4YAA A;  1C83 A;  4JMJ A;  1Q6S A;  3QKP A;  1Q6J A;  1Q1M A;  2F70 A;  4H1O A;  3F9A A;  3H2X A;  4GRY A;  2CNH A;  4MBB A;  2I1Y A;  2I6P A;  2HB1 A;  3S3H A;  2DXP A;  5KAC A;  2CM3 A;  3V0J A;  4RI4 A;  3GXH A;  3EU0 A;  2J16 A;  3I7Z A;  1G4W R;  2QCJ A;  4OHL A;  2HC1 A;  4GE5 A;  2C7S A;  4QBW A;  1PTU A;  4HJP A;  1ZZW A;  2HNP A;  2I75 A;  5K9W A;  3NME A;  2PA5 A;  1ZC0 A;  2F6Z A;  2C46 A;  3MMJ A;  4QAP A;  1Q6P A;  1XBO A;  1LYV A;  1P15 A;  3BLT A;  2M3V A;  3V0G A;  2B4O A;  5KA8 A;  2I6I A;  1J4X A;  2OZ5 A;  2HY3 A;  3O4S A;  3F41 A;  4ICZ A;  2WGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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