4RH9A

Crystal structure of ptpn3 (ptph1) h812f, m883g mutant in complex with eps15 ptyr849 peptide
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
282
structure length
282
Chain Sequence
ADTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPAFGVPDDSSDFLEFVNYVRSLRVDSEPVLVHSSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAGMVQTSSQYKFVCEAILRVYEEGLVQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 3
total genus 91
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4rh9A00
4GE6A 2F6VA 2J16B 3QCEA 4JBCA 5KA1A 3F9BA 3F81A 1FPZA 3EZZA 4H1OA 3QCHA 1C84A 1Q6PA 1JLNA 1XBOA 3ZM1A 1QZ0A 3QCLA 1JF7A 1U25A 3QCCA 2G59A 1BZCA 1OHCA 3QCDA 5BZXA 2HNQA 3V0EA 2HCMA 1EENA 1Q6JA 4DGPA 2CM2A 4RDDA 4MBBA 3D1QA 1ONYA 4QUMA 2BGDA 2JJDA 5BX1A 2G6ZA 2I6PA 2F6ZA 2HC2A 1OEMX 3OLRA 2CM7A 1Q6SA 2ZN7A 1L8GA 1Q6MA 2F71A 2H4KA 4Y14A 2DXPA 3AWEA 3ZMPA 2NT2A 4YR8B 1G1HA 4QBEA 3S3KA 4TVVA 2GP0A 4OHIA 1YWFA 3V0GA 1BZJA 2H4VA 5KA3A 1YZ4A 2GWOA 3D9CA 2IMGA 2CNFA 2B49A 5KA7A 2QDMA 2B07A 2QEPA 5K25A 5IBMA 1A5YA 3D42A 3QCKA 3QKPA 4NNDA 4WU3A 3CWEA 4OHDA 2VEUA 1GWZA 3I36A 1PYNA 2F6TA 4ICZA 4BJOA 4BPCA 5KADA 4JMJA 5EHRA 1Q6TA 2J16A 1YGRA 4NYHA 1NWEA 1XXPA 4S0GA 1P15A 5K22A 4DGXA 3N0AA 3S4OA 2P4DA 4RI5A 3QCBA 2NTAA 3GXGA 2M3VA 3BRHA 3QKQA 5GTJA 2B3OA 2OC3A 4R0TA 2PT0A 3D1HA 4NWFA 2NLKA 2I42A 2HNPA 4JNBA 1KAVA 4RH5A 1YTNA 4OHEA 1ONZA 2VEYA 1PXHA 1RXDA 3ZMQA 4GWFA 1KAKA 2F6WA 2CJZA 2AZRA 2OUDA 1I9SA 2F70A 4QAPA 2QBQA 4PYHA 4OHLA 2I4EA 4HRFA 5K9VA 4QBWA 4J51A 1WRMA 2FJMA 1M3GA 4YAAA 4ERCA 2I5XA 2QDCA 2QDPA 2QCJA 5EHPA 5BUGA 3V0JA 1EEOA 1X24A 1WCHA 3F41A 2I3RA 5K23A 1Q1MA 4QAHA 1YFOA 2F6YA 2HB1A 3MOZA 2HXPA 2MBCA 2PSZA 2VEXA 2E0TA 2CNIA 3RO1A 2I6IA 3V0DA 4Z6BA 4R30A 5KACA 1YTWA 2H4GA 1C87A 2NZ6A 2I6MA 2I6OA 3V0HA 4GE5A 4WTYA 1RPMA 3NMEA 3O4UA 5KABA 4GS0A 2F6FA 3S3FA 3SMEA 2HC1A 1AAXA 2FH7A 4I8NA 2I6JA 3ZM0A 4KYQA 3SR9A 5K24A 2B4OA 1G1GA 3EB1A 1OEVA 3LJ8A 4GRYA 4RI4A 4GFUA 1OESA 3OMHA 2AHSA 1G7GA 2CM8A 4GE2A 1OETA 1J4XA 2ESBA 2R0BA 2Q47A 2PA5A 1PTVA 3QCMA 3BM8A 1G1FA 3A5JA 3MMJA 4GFVA 2HY3A 1PA9A 2QBRA 1PH0A 2H03A 3CM3A 2VEVA 4NX8A 4R0SA 4WU2A 2QBPA 1ZZWA 1T4JA 3QCIA 2H02A 1T49A 2PBNA 1LYVA 2NV5A 2PQ5A 3MOWA 2C46A 2FJNA 1NZ7A 2PI7A 2I4GA 3I7ZA 1NO6A 3F99A 2CMBA 1MKPA 3ZV2A 3AWGA 3RGQA 5AWXA 5MMZB 1WAXA 2CMCA 1PTUA 1YTSA 2NT7A 1NL9A 1C83A 5BZZA 2A8BA 2YDUA 4D3RA 2BGEA 1Q6NA 2J17A 4H34A 2F46A 1I57A 1YPTA 3AWFA 1L8KA 2I4HA 2H04A 1SUGA 4HJPA 5IBSA 3RGOA 5M43A 3QCGA 1ZCKA 5KA2A 4AZ1A 3O4TA 3D44A 1FPRA 1C85A 5KA4A 2BIJA 2B4SA 2HVLA 1PTYA 1BZHA 2CNHA 2P6XA 2QCTA 5K9WA 2ZMMA 2I3UA 3V0IA 1FQ1A 1XM2A 5I6VA 1R6HA 4QUNA 1XXVA 4PVGA 1C88A 3B7OA 1OEUA 2CFVA 3QCJA 1VHRA 3ZM3A 4HJQA 4ZN5A 3A5KA 3U96A 5KAAA 2B4UA 2CNGA 4B04A 3I80A 4NWGA 1I9TA 1PTTA 3BLUA 3BLTA 4OHHA 1C86A 3O4SA 3S4EA 2CMAA 1OHEA 4KYRA 5J8RA 2B4PA 3PS5A 4RHGA 4WOHA 1ZC0A 3M4UA 3H2XA 1GFYA 1YN9A 1G4US 3D1OA 2OOQA 1D5RA 3QCNA 4JMKA 4GRZA 1PA1A 3S3HA 4ZRTA 5HDEA 1NNYA 1LQFA 1G7FA 2VEWA 4Y2EA 4ZI4A 1NWLA 2CM3A 1QXKA 2Y2FA 2Q05A 4D3QA 2RF6A 3S3EA 3RZ2A 1G4WR 1OHDA 1T48A 5KA8A 1U26A 3EMUA 4KI9A 2BZLA 1V3AA 2WGPA 4RH9A 4RKKA 3O3LA 1YGUA 2SHPA 2OZ5A 2Y96A 5LXQB 5KA0A 3EAXA 1ZCLA 2QBSA 2GJTA 3O5XA 4D3PA 1LARA 5KA9A 2I1YA 3EU0A 3V0FA 3GXHA 3QCFA 1ECVA 3F9AA 2I75A 2A3KA 1XRIA 2CNEA 1OEOX 4IKCA 2BV5A 2C7SA 1U24A 3ZM2A
chains in the Genus database with same CATH superfamily
3N2AA 4GE6A 2F6VA 2J16B 3UAGA 3QCEA 4JBCA 5KA1A 3F9BA 3F81A 1FPZA 3EZZA 4H1OA 2VORA 3QCHA 1C84A 1Q6PA 2XJAA 1JLNA 1XBOA 3ZM1A 1QZ0A 3QCLA 1JF7A 1U25A 3QCCA 2G59A 1BZCA 2VOSA 1OHCA 3QCDA 5BZXA 2HNQA 3V0EA 2HCMA 1EENA 1Q6JA 4DGPA 2CM2A 4RDDA 4MBBA 3D1QA 1ONYA 4QUMA 2BGDA 2JJDA 5BX1A 2G6ZA 2I6PA 2F6ZA 2HC2A 1OEMX 3NRSA 3OLRA 2CM7A 1Q6SA 2ZN7A 1L8GA 2F00A 1Q6MA 2F71A 2H4KA 4Y14A 2DXPA 3AWEA 3ZMPA 2AM1A 2NT2A 4YR8B 1G1HA 4QBEA 1GQQA 3S3KA 4TVVA 2UAGA 2GP0A 4OHIA 1YWFA 3V0GA 1BZJA 2H4VA 5KA3A 1YZ4A 2GWOA 3D9CA 3QCZA 2IMGA 2CNFA 2B49A 5KA7A 2QDMA 2XPCA 2B07A 3MVNA 2QEPA 5K25A 5IBMA 1A5YA 3D42A 3QCKA 3LK7A 3QKPA 4NNDA 4WU3A 4CVMA 3CWEA 4OHDA 2VEUA 1GWZA 1FGSA 3I36A 1PYNA 2F6TA 4ICZA 4BJOA 4BPCA 5KADA 4JMJA 4HV4A 5EHRA 1Q6TA 2J16A 1YGRA 4NYHA 1NWEA 1XXPA 4S0GA 1P15A 5K22A 4DGXA 3N0AA 3S4OA 2P4DA 4RI5A 3QCBA 2NTAA 3GXGA 2M3VA 3BRHA 3QKQA 5GTJA 2B3OA 2OC3A 4R0TA 2PT0A 3D1HA 4NWFA 2NLKA 1UAGA 2I42A 2HNPA 2JFGA 4JNBA 1KAVA 4RH5A 1YTNA 4OHEA 1ONZA 4CVKA 2VEYA 1PXHA 1RXDA 3ZMQA 4GWFA 1KAKA 2F6WA 2CJZA 2GCBA 2AZRA 2OUDA 1I9SA 2F70A 4QAPA 2QBQA 4PYHA 4OHLA 2I4EA 1W78A 4HRFA 4BUCA 5K9VA 4QBWA 4J51A 1WRMA 2FJMA 1M3GA 4YAAA 4ERCA 2I5XA 2QDCA 2QDPA 2QCJA 5EHPA 5BUGA 3V0JA 1EEOA 1X24A 1WCHA 3F41A 2I3RA 5K23A 1Q1MA 4QAHA 1YFOA 2F6YA 2HB1A 3MOZA 2HXPA 2MBCA 2PSZA 2VEXA 2E0TA 2CNIA 3RO1A 5A5EA 1E0DA 2I6IA 3V0DA 4Z6BA 4R30A 5KACA 1YTWA 2H4GA 1C87A 2NZ6A 2I6MA 2I6OA 1JBWA 3V0HA 4GE5A 4WTYA 1RPMA 3NMEA 4QF5A 3O4UA 5A5FA 5KABA 4GS0A 2F6FA 3S3FA 3SMEA 2Y66A 2HC1A 1AAXA 2FH7A 4I8NA 2I6JA 3ZM0A 4KYQA 3SR9A 5K24A 2B4OA 1G1GA 3EB1A 1OEVA 1GG4A 3LJ8A 1E8CA 1O5ZA 4GRYA 2GC6A 4RI4A 4QDIA 1GQYA 4GFUA 1OESA 3OMHA 3PYZA 2AHSA 1G7GA 2CM8A 4GE2A 1OETA 1J4XA 2Y67A 1J6UA 2ESBA 2R0BA 4C13A 2Q47A 2PA5A 1PTVA 3HN7A 3QCMA 3BM8A 1G1FA 3A5JA 3MMJA 4GFVA 2HY3A 1PA9A 2QBRA 1PH0A 4ZIYA 2H03A 3CM3A 2VEVA 3ZM6A 4NX8A 4R0SA 4WU2A 2QBPA 1ZZWA 1T4JA 3QCIA 2H02A 1T49A 2PBNA 1LYVA 2NV5A 2PQ5A 3MOWA 2C46A 2FJNA 1NZ7A 2PI7A 2I4GA 3I7ZA 1NO6A 3F99A 2CMBA 1MKPA 3ZV2A 3AWGA 3RGQA 5AWXA 5MMZB 1WAXA 2CMCA 1PTUA 1YTSA 2NT7A 1NL9A 1C83A 2X5OA 5BZZA 2A8BA 4BUBA 2YDUA 4D3RA 2BGEA 1Q6NA 2J17A 4H34A 2F46A 1I57A 1W7KA 1YPTA 3AWFA 1L8KA 2VTDA 2I4HA 2H04A 1SUGA 4HJPA 5IBSA 3RGOA 5M43A 3QCGA 2JFFA 1ZCKA 2UUOA 5KA2A 4AZ1A 3D44A 3O4TA 1FPRA 1C85A 5KA4A 2BIJA 2B4SA 2HVLA 1PTYA 1BZHA 2CNHA 2P6XA 2QCTA 2Y68A 3ZM5A 5K9WA 2ZMMA 2I3UA 3V0IA 1FQ1A 1XM2A 5I6VA 1R6HA 4QUNA 1XXVA 4PVGA 1C88A 3B7OA 1OEUA 2CFVA 3QCJA 1VHRA 3ZM3A 2GC5A 4HJQA 4ZN5A 2UUPA 3A5KA 2WTZA 1EEHA 2GCAA 3U96A 5KAAA 2B4UA 2CNGA 4B04A 3I80A 4NWGA 1I9TA 1PTTA 3BLUA 3BLTA 4OHHA 1C86A 4UAGA 3O4SA 3S4EA 2CMAA 1OHEA 4KYRA 5J8RA 2B4PA 3PS5A 4RHGA 4WOHA 1ZC0A 1P31A 3H2XA 3M4UA 1GFYA 1JBVA 1YN9A 1G4US 3D1OA 2OOQA 3ZL8A 1D5RA 3QCNA 4JMKA 4GRZA 1PA1A 3S3HA 4ZRTA 5HDEA 1NNYA 1LQFA 1G7FA 1P3DA 2VEWA 4Y2EA 4ZI4A 1NWLA 2CM3A 1QXKA 2Y2FA 2Y1OA 2Q05A 4D3QA 2RF6A 3S3EA 3RZ2A 1G4WR 1OHDA 1T48A 5KA8A 1U26A 3EMUA 4KI9A 2BZLA 1V3AA 2WGPA 4RH9A 4RKKA 3O3LA 1YGUA 2SHPA 2OZ5A 2Y96A 5LXQB 5KA0A 3EAXA 1ZCLA 2QBSA 2GJTA 3O5XA 2JFHA 4D3PA 1LARA 5KA9A 2I1YA 3EU0A 2AM2A 3V0FA 2VTEA 3GXHA 4C12A 3QCFA 1ECVA 3F9AA 2I75A 2A3KA 2WJPA 1XRIA 2CNEA 1OEOX 4IKCA 2BV5A 2C7SA 1U24A 4CVLA 3ZM2A
chains in the Genus database with same CATH topology
4GE6A 2F6VA 2J16B 3QCEA 4JBCA 5KA1A 3F9BA 3F81A 1FPZA 3EZZA 4H1OA 3QCHA 1C84A 1Q6PA 1JLNA 1XBOA 3ZM1A 1QZ0A 3QCLA 1JF7A 1U25A 3QCCA 2G59A 1BZCA 1OHCA 3QCDA 5BZXA 2HNQA 3V0EA 2HCMA 1EENA 1Q6JA 4DGPA 2CM2A 4RDDA 4MBBA 3D1QA 1ONYA 4QUMA 2BGDA 2JJDA 5BX1A 2G6ZA 2I6PA 2F6ZA 2HC2A 1OEMX 3OLRA 2CM7A 1Q6SA 2ZN7A 1L8GA 1Q6MA 2F71A 2H4KA 4Y14A 2DXPA 3AWEA 3ZMPA 2NT2A 4YR8B 1G1HA 4QBEA 3S3KA 4TVVA 2GP0A 4OHIA 1YWFA 3V0GA 1BZJA 2H4VA 5KA3A 1YZ4A 2GWOA 3D9CA 2IMGA 2CNFA 2B49A 5KA7A 2QDMA 2B07A 2QEPA 5K25A 5IBMA 1A5YA 3D42A 3QCKA 3QKPA 4NNDA 4WU3A 3CWEA 4OHDA 2VEUA 1GWZA 3I36A 1PYNA 2F6TA 4ICZA 4BJOA 4BPCA 5KADA 4JMJA 5EHRA 1Q6TA 2J16A 1YGRA 4NYHA 1NWEA 1XXPA 4S0GA 1P15A 5K22A 4DGXA 3N0AA 3S4OA 2P4DA 4RI5A 3QCBA 2NTAA 3GXGA 2M3VA 3BRHA 3QKQA 5GTJA 2B3OA 2OC3A 4R0TA 2PT0A 3D1HA 4NWFA 2NLKA 2I42A 2HNPA 4JNBA 1KAVA 4RH5A 1YTNA 4OHEA 1ONZA 2VEYA 1PXHA 1RXDA 3ZMQA 4GWFA 1KAKA 2F6WA 2CJZA 2AZRA 2OUDA 1I9SA 2F70A 4QAPA 2QBQA 4PYHA 4OHLA 2I4EA 4HRFA 5K9VA 4QBWA 4J51A 1WRMA 2FJMA 1M3GA 4YAAA 4ERCA 2I5XA 2QDCA 2QDPA 2QCJA 5EHPA 5BUGA 3V0JA 1EEOA 1X24A 1WCHA 3F41A 2I3RA 5K23A 1Q1MA 4QAHA 1YFOA 2F6YA 2HB1A 3MOZA 2HXPA 2MBCA 2PSZA 2VEXA 2E0TA 2CNIA 3RO1A 2I6IA 3V0DA 4Z6BA 4R30A 5KACA 1YTWA 2H4GA 1C87A 2NZ6A 2I6MA 2I6OA 3V0HA 4GE5A 4WTYA 1RPMA 3NMEA 3O4UA 5KABA 4GS0A 2F6FA 3S3FA 3SMEA 2HC1A 1AAXA 2FH7A 4I8NA 2I6JA 3ZM0A 4KYQA 3SR9A 5K24A 2B4OA 1G1GA 3EB1A 1OEVA 3LJ8A 4GRYA 4RI4A 4GFUA 1OESA 3OMHA 2AHSA 1G7GA 2CM8A 4GE2A 1OETA 1J4XA 2ESBA 2R0BA 2Q47A 2PA5A 1PTVA 3QCMA 3BM8A 1G1FA 3A5JA 3MMJA 4GFVA 2HY3A 1PA9A 2QBRA 1PH0A 2H03A 3CM3A 2VEVA 4NX8A 4R0SA 4WU2A 2QBPA 1ZZWA 1T4JA 3QCIA 2H02A 1T49A 2PBNA 1LYVA 2NV5A 2PQ5A 3MOWA 2C46A 2FJNA 1NZ7A 2PI7A 2I4GA 3I7ZA 1NO6A 3F99A 2CMBA 1MKPA 3ZV2A 3AWGA 3RGQA 5AWXA 5MMZB 1WAXA 2CMCA 1PTUA 1YTSA 2NT7A 1NL9A 1C83A 5BZZA 2A8BA 2YDUA 4D3RA 2BGEA 1Q6NA 2J17A 4H34A 2F46A 1I57A 1YPTA 3AWFA 1L8KA 2I4HA 2H04A 1SUGA 4HJPA 5IBSA 3RGOA 5M43A 3QCGA 1ZCKA 5KA2A 4AZ1A 3O4TA 3D44A 1FPRA 1C85A 5KA4A 2BIJA 2B4SA 2HVLA 1PTYA 1BZHA 2CNHA 2P6XA 2QCTA 5K9WA 2ZMMA 2I3UA 3V0IA 1FQ1A 1XM2A 5I6VA 1R6HA 4QUNA 1XXVA 4PVGA 1C88A 3B7OA 1OEUA 2CFVA 3QCJA 1VHRA 3ZM3A 4HJQA 4ZN5A 3A5KA 3U96A 5KAAA 2B4UA 2CNGA 4B04A 3I80A 4NWGA 1I9TA 1PTTA 3BLUA 3BLTA 4OHHA 1C86A 3O4SA 3S4EA 2CMAA 1OHEA 4KYRA 5J8RA 2B4PA 3PS5A 4RHGA 4WOHA 1ZC0A 3M4UA 3H2XA 1GFYA 1YN9A 1G4US 3D1OA 2OOQA 1D5RA 3QCNA 4JMKA 4GRZA 1PA1A 3S3HA 4ZRTA 5HDEA 1NNYA 1LQFA 1G7FA 2VEWA 4Y2EA 4ZI4A 1NWLA 2CM3A 1QXKA 2Y2FA 2Q05A 4D3QA 2RF6A 3S3EA 3RZ2A 1G4WR 1OHDA 1T48A 5KA8A 1U26A 3EMUA 4KI9A 2BZLA 1V3AA 2WGPA 4RH9A 4RKKA 3O3LA 1YGUA 2SHPA 2OZ5A 2Y96A 5LXQB 5KA0A 3EAXA 1ZCLA 2QBSA 2GJTA 3O5XA 4D3PA 1LARA 5KA9A 2I1YA 3EU0A 3V0FA 3GXHA 3QCFA 1ECVA 3F9AA 2I75A 2A3KA 1XRIA 2CNEA 1OEOX 4IKCA 2BV5A 2C7SA 1U24A 3ZM2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GE6 A;  2F6V A;  2J16 B;  3QCE A;  4JBC A;  5KA1 A;  3F9B A;  3F81 A;  1FPZ A;  3EZZ A;  4H1O A;  3QCH A;  1C84 A;  1Q6P A;  1JLN A;  1XBO A;  3ZM1 A;  1QZ0 A;  3QCL A;  1JF7 A;  1U25 A;  3QCC A;  2G59 A;  1BZC A;  1OHC A;  3QCD A;  5BZX A;  2HNQ A;  3V0E A;  2HCM A;  1EEN A;  1Q6J A;  4DGP A;  2CM2 A;  4RDD A;  4MBB A;  3D1Q A;  1ONY A;  4QUM A;  2BGD A;  2JJD A;  5BX1 A;  2G6Z A;  2I6P A;  2F6Z A;  2HC2 A;  1OEM X;  3OLR A;  2CM7 A;  1Q6S A;  2ZN7 A;  1L8G A;  1Q6M A;  2F71 A;  2H4K A;  4Y14 A;  2DXP A;  3AWE A;  3ZMP A;  2NT2 A;  4YR8 B;  1G1H A;  4QBE A;  3S3K A;  4TVV A;  2GP0 A;  4OHI A;  1YWF A;  3V0G A;  1BZJ A;  2H4V A;  5KA3 A;  1YZ4 A;  2GWO A;  3D9C A;  2IMG A;  2CNF A;  2B49 A;  5KA7 A;  2QDM A;  2B07 A;  2QEP A;  5K25 A;  5IBM A;  1A5Y A;  3D42 A;  3QCK A;  3QKP A;  4NND A;  4WU3 A;  3CWE A;  4OHD A;  2VEU A;  1GWZ A;  3I36 A;  1PYN A;  2F6T A;  4ICZ A;  4BJO A;  4BPC A;  5KAD A;  4JMJ A;  5EHR A;  1Q6T A;  2J16 A;  1YGR A;  4NYH A;  1NWE A;  1XXP A;  4S0G A;  1P15 A;  5K22 A;  4DGX A;  3N0A A;  3S4O A;  2P4D A;  4RI5 A;  3QCB A;  2NTA A;  3GXG A;  2M3V A;  3BRH A;  3QKQ A;  5GTJ A;  2B3O A;  2OC3 A;  4R0T A;  2PT0 A;  3D1H A;  4NWF A;  2NLK A;  2I42 A;  2HNP A;  4JNB A;  1KAV A;  4RH5 A;  1YTN A;  4OHE A;  1ONZ A;  2VEY A;  1PXH A;  1RXD A;  3ZMQ A;  4GWF A;  1KAK A;  2F6W A;  2CJZ A;  2AZR A;  2OUD A;  1I9S A;  2F70 A;  4QAP A;  2QBQ A;  4PYH A;  4OHL A;  2I4E A;  4HRF A;  5K9V A;  4QBW A;  4J51 A;  1WRM A;  2FJM A;  1M3G A;  4YAA A;  4ERC A;  2I5X A;  2QDC A;  2QDP A;  2QCJ A;  5EHP A;  5BUG A;  3V0J A;  1EEO A;  1X24 A;  1WCH A;  3F41 A;  2I3R A;  5K23 A;  1Q1M A;  4QAH A;  1YFO A;  2F6Y A;  2HB1 A;  3MOZ A;  2HXP A;  2MBC A;  2PSZ A;  2VEX A;  2E0T A;  2CNI A;  3RO1 A;  2I6I A;  3V0D A;  4Z6B A;  4R30 A;  5KAC A;  1YTW A;  2H4G A;  1C87 A;  2NZ6 A;  2I6M A;  2I6O A;  3V0H A;  4GE5 A;  4WTY A;  1RPM A;  3NME A;  3O4U A;  5KAB A;  4GS0 A;  2F6F A;  3S3F A;  3SME A;  2HC1 A;  1AAX A;  2FH7 A;  4I8N A;  2I6J A;  3ZM0 A;  4KYQ A;  3SR9 A;  5K24 A;  2B4O A;  1G1G A;  3EB1 A;  1OEV A;  3LJ8 A;  4GRY A;  4RI4 A;  4GFU A;  1OES A;  3OMH A;  2AHS A;  1G7G A;  2CM8 A;  4GE2 A;  1OET A;  1J4X A;  2ESB A;  2R0B A;  2Q47 A;  2PA5 A;  1PTV A;  3QCM A;  3BM8 A;  1G1F A;  3A5J A;  3MMJ A;  4GFV A;  2HY3 A;  1PA9 A;  2QBR A;  1PH0 A;  2H03 A;  3CM3 A;  2VEV A;  4NX8 A;  4R0S A;  4WU2 A;  2QBP A;  1ZZW A;  1T4J A;  3QCI A;  2H02 A;  1T49 A;  2PBN A;  1LYV A;  2NV5 A;  2PQ5 A;  3MOW A;  2C46 A;  2FJN A;  1NZ7 A;  2PI7 A;  2I4G A;  3I7Z A;  1NO6 A;  3F99 A;  2CMB A;  1MKP A;  3ZV2 A;  3AWG A;  3RGQ A;  5AWX A;  5MMZ B;  1WAX A;  2CMC A;  1PTU A;  1YTS A;  2NT7 A;  1NL9 A;  1C83 A;  5BZZ A;  2A8B A;  2YDU A;  4D3R A;  2BGE A;  1Q6N A;  2J17 A;  4H34 A;  2F46 A;  1I57 A;  1YPT A;  3AWF A;  1L8K A;  2I4H A;  2H04 A;  1SUG A;  4HJP A;  5IBS A;  3RGO A;  5M43 A;  3QCG A;  1ZCK A;  5KA2 A;  4AZ1 A;  3O4T A;  3D44 A;  1FPR A;  1C85 A;  5KA4 A;  2BIJ A;  2B4S A;  2HVL A;  1PTY A;  1BZH A;  2CNH A;  2P6X A;  2QCT A;  5K9W A;  2ZMM A;  2I3U A;  3V0I A;  1FQ1 A;  1XM2 A;  5I6V A;  1R6H A;  4QUN A;  1XXV A;  4PVG A;  1C88 A;  3B7O A;  1OEU A;  2CFV A;  3QCJ A;  1VHR A;  3ZM3 A;  4HJQ A;  4ZN5 A;  3A5K A;  3U96 A;  5KAA A;  2B4U A;  2CNG A;  4B04 A;  3I80 A;  4NWG A;  1I9T A;  1PTT A;  3BLU A;  3BLT A;  4OHH A;  1C86 A;  3O4S A;  3S4E A;  2CMA A;  1OHE A;  4KYR A;  5J8R A;  2B4P A;  3PS5 A;  4RHG A;  4WOH A;  1ZC0 A;  3M4U A;  3H2X A;  1GFY A;  1YN9 A;  1G4U S;  3D1O A;  2OOQ A;  1D5R A;  3QCN A;  4JMK A;  4GRZ A;  1PA1 A;  3S3H A;  4ZRT A;  5HDE A;  1NNY A;  1LQF A;  1G7F A;  2VEW A;  4Y2E A;  4ZI4 A;  1NWL A;  2CM3 A;  1QXK A;  2Y2F A;  2Q05 A;  4D3Q A;  2RF6 A;  3S3E A;  3RZ2 A;  1G4W R;  1OHD A;  1T48 A;  5KA8 A;  1U26 A;  3EMU A;  4KI9 A;  2BZL A;  1V3A A;  2WGP A;  4RH9 A;  4RKK A;  3O3L A;  1YGU A;  2SHP A;  2OZ5 A;  2Y96 A;  5LXQ B;  5KA0 A;  3EAX A;  1ZCL A;  2QBS A;  2GJT A;  3O5X A;  4D3P A;  1LAR A;  5KA9 A;  2I1Y A;  3EU0 A;  3V0F A;  3GXH A;  3QCF A;  1ECV A;  3F9A A;  2I75 A;  2A3K A;  1XRI A;  2CNE A;  1OEO X;  4IKC A;  2BV5 A;  2C7S A;  1U24 A;  3ZM2 A; 
#chains in the Genus database with same CATH topology
 3N2A A;  4GE6 A;  2F6V A;  2J16 B;  3UAG A;  3QCE A;  4JBC A;  5KA1 A;  3F9B A;  3F81 A;  1FPZ A;  3EZZ A;  4H1O A;  2VOR A;  3QCH A;  1C84 A;  1Q6P A;  2XJA A;  1JLN A;  1XBO A;  3ZM1 A;  1QZ0 A;  3QCL A;  1JF7 A;  1U25 A;  3QCC A;  2G59 A;  1BZC A;  2VOS A;  1OHC A;  3QCD A;  5BZX A;  2HNQ A;  3V0E A;  2HCM A;  1EEN A;  1Q6J A;  4DGP A;  2CM2 A;  4RDD A;  4MBB A;  3D1Q A;  1ONY A;  4QUM A;  2BGD A;  2JJD A;  5BX1 A;  2G6Z A;  2I6P A;  2F6Z A;  2HC2 A;  1OEM X;  3NRS A;  3OLR A;  2CM7 A;  1Q6S A;  2ZN7 A;  1L8G A;  2F00 A;  1Q6M A;  2F71 A;  2H4K A;  4Y14 A;  2DXP A;  3AWE A;  3ZMP A;  2AM1 A;  2NT2 A;  4YR8 B;  1G1H A;  4QBE A;  1GQQ A;  3S3K A;  4TVV A;  2UAG A;  2GP0 A;  4OHI A;  1YWF A;  3V0G A;  1BZJ A;  2H4V A;  5KA3 A;  1YZ4 A;  2GWO A;  3D9C A;  3QCZ A;  2IMG A;  2CNF A;  2B49 A;  5KA7 A;  2QDM A;  2XPC A;  2B07 A;  3MVN A;  2QEP A;  5K25 A;  5IBM A;  1A5Y A;  3D42 A;  3QCK A;  3LK7 A;  3QKP A;  4NND A;  4WU3 A;  4CVM A;  3CWE A;  4OHD A;  2VEU A;  1GWZ A;  1FGS A;  3I36 A;  1PYN A;  2F6T A;  4ICZ A;  4BJO A;  4BPC A;  5KAD A;  4JMJ A;  4HV4 A;  5EHR A;  1Q6T A;  2J16 A;  1YGR A;  4NYH A;  1NWE A;  1XXP A;  4S0G A;  1P15 A;  5K22 A;  4DGX A;  3N0A A;  3S4O A;  2P4D A;  4RI5 A;  3QCB A;  2NTA A;  3GXG A;  2M3V A;  3BRH A;  3QKQ A;  5GTJ A;  2B3O A;  2OC3 A;  4R0T A;  2PT0 A;  3D1H A;  4NWF A;  2NLK A;  1UAG A;  2I42 A;  2HNP A;  2JFG A;  4JNB A;  1KAV A;  4RH5 A;  1YTN A;  4OHE A;  1ONZ A;  4CVK A;  2VEY A;  1PXH A;  1RXD A;  3ZMQ A;  4GWF A;  1KAK A;  2F6W A;  2CJZ A;  2GCB A;  2AZR A;  2OUD A;  1I9S A;  2F70 A;  4QAP A;  2QBQ A;  4PYH A;  4OHL A;  2I4E A;  1W78 A;  4HRF A;  4BUC A;  5K9V A;  4QBW A;  4J51 A;  1WRM A;  2FJM A;  1M3G A;  4YAA A;  4ERC A;  2I5X A;  2QDC A;  2QDP A;  2QCJ A;  5EHP A;  5BUG A;  3V0J A;  1EEO A;  1X24 A;  1WCH A;  3F41 A;  2I3R A;  5K23 A;  1Q1M A;  4QAH A;  1YFO A;  2F6Y A;  2HB1 A;  3MOZ A;  2HXP A;  2MBC A;  2PSZ A;  2VEX A;  2E0T A;  2CNI A;  3RO1 A;  5A5E A;  1E0D A;  2I6I A;  3V0D A;  4Z6B A;  4R30 A;  5KAC A;  1YTW A;  2H4G A;  1C87 A;  2NZ6 A;  2I6M A;  2I6O A;  1JBW A;  3V0H A;  4GE5 A;  4WTY A;  1RPM A;  3NME A;  4QF5 A;  3O4U A;  5A5F A;  5KAB A;  4GS0 A;  2F6F A;  3S3F A;  3SME A;  2Y66 A;  2HC1 A;  1AAX A;  2FH7 A;  4I8N A;  2I6J A;  3ZM0 A;  4KYQ A;  3SR9 A;  5K24 A;  2B4O A;  1G1G A;  3EB1 A;  1OEV A;  1GG4 A;  3LJ8 A;  1E8C A;  1O5Z A;  4GRY A;  2GC6 A;  4RI4 A;  4QDI A;  1GQY A;  4GFU A;  1OES A;  3OMH A;  3PYZ A;  2AHS A;  1G7G A;  2CM8 A;  4GE2 A;  1OET A;  1J4X A;  2Y67 A;  1J6U A;  2ESB A;  2R0B A;  4C13 A;  2Q47 A;  2PA5 A;  1PTV A;  3HN7 A;  3QCM A;  3BM8 A;  1G1F A;  3A5J A;  3MMJ A;  4GFV A;  2HY3 A;  1PA9 A;  2QBR A;  1PH0 A;  4ZIY A;  2H03 A;  3CM3 A;  2VEV A;  3ZM6 A;  4NX8 A;  4R0S A;  4WU2 A;  2QBP A;  1ZZW A;  1T4J A;  3QCI A;  2H02 A;  1T49 A;  2PBN A;  1LYV A;  2NV5 A;  2PQ5 A;  3MOW A;  2C46 A;  2FJN A;  1NZ7 A;  2PI7 A;  2I4G A;  3I7Z A;  1NO6 A;  3F99 A;  2CMB A;  1MKP A;  3ZV2 A;  3AWG A;  3RGQ A;  5AWX A;  5MMZ B;  1WAX A;  2CMC A;  1PTU A;  1YTS A;  2NT7 A;  1NL9 A;  1C83 A;  2X5O A;  5BZZ A;  2A8B A;  4BUB A;  2YDU A;  4D3R A;  2BGE A;  1Q6N A;  2J17 A;  4H34 A;  2F46 A;  1I57 A;  1W7K A;  1YPT A;  3AWF A;  1L8K A;  2VTD A;  2I4H A;  2H04 A;  1SUG A;  4HJP A;  5IBS A;  3RGO A;  5M43 A;  3QCG A;  2JFF A;  1ZCK A;  2UUO A;  5KA2 A;  4AZ1 A;  3D44 A;  3O4T A;  1FPR A;  1C85 A;  5KA4 A;  2BIJ A;  2B4S A;  2HVL A;  1PTY A;  1BZH A;  2CNH A;  2P6X A;  2QCT A;  2Y68 A;  3ZM5 A;  5K9W A;  2ZMM A;  2I3U A;  3V0I A;  1FQ1 A;  1XM2 A;  5I6V A;  1R6H A;  4QUN A;  1XXV A;  4PVG A;  1C88 A;  3B7O A;  1OEU A;  2CFV A;  3QCJ A;  1VHR A;  3ZM3 A;  2GC5 A;  4HJQ A;  4ZN5 A;  2UUP A;  3A5K A;  2WTZ A;  1EEH A;  2GCA A;  3U96 A;  5KAA A;  2B4U A;  2CNG A;  4B04 A;  3I80 A;  4NWG A;  1I9T A;  1PTT A;  3BLU A;  3BLT A;  4OHH A;  1C86 A;  4UAG A;  3O4S A;  3S4E A;  2CMA A;  1OHE A;  4KYR A;  5J8R A;  2B4P A;  3PS5 A;  4RHG A;  4WOH A;  1ZC0 A;  1P31 A;  3H2X A;  3M4U A;  1GFY A;  1JBV A;  1YN9 A;  1G4U S;  3D1O A;  2OOQ A;  3ZL8 A;  1D5R A;  3QCN A;  4JMK A;  4GRZ A;  1PA1 A;  3S3H A;  4ZRT A;  5HDE A;  1NNY A;  1LQF A;  1G7F A;  1P3D A;  2VEW A;  4Y2E A;  4ZI4 A;  1NWL A;  2CM3 A;  1QXK A;  2Y2F A;  2Y1O A;  2Q05 A;  4D3Q A;  2RF6 A;  3S3E A;  3RZ2 A;  1G4W R;  1OHD A;  1T48 A;  5KA8 A;  1U26 A;  3EMU A;  4KI9 A;  2BZL A;  1V3A A;  2WGP A;  4RH9 A;  4RKK A;  3O3L A;  1YGU A;  2SHP A;  2OZ5 A;  2Y96 A;  5LXQ B;  5KA0 A;  3EAX A;  1ZCL A;  2QBS A;  2GJT A;  3O5X A;  2JFH A;  4D3P A;  1LAR A;  5KA9 A;  2I1Y A;  3EU0 A;  2AM2 A;  3V0F A;  2VTE A;  3GXH A;  4C12 A;  3QCF A;  1ECV A;  3F9A A;  2I75 A;  2A3K A;  2WJP A;  1XRI A;  2CNE A;  1OEO X;  4IKC A;  2BV5 A;  2C7S A;  1U24 A;  4CVL A;  3ZM2 A; 
#chains in the Genus database with same CATH homology
 4GE6 A;  2F6V A;  2J16 B;  3QCE A;  4JBC A;  5KA1 A;  3F9B A;  3F81 A;  1FPZ A;  3EZZ A;  4H1O A;  3QCH A;  1C84 A;  1Q6P A;  1JLN A;  1XBO A;  3ZM1 A;  1QZ0 A;  3QCL A;  1JF7 A;  1U25 A;  3QCC A;  2G59 A;  1BZC A;  1OHC A;  3QCD A;  5BZX A;  2HNQ A;  3V0E A;  2HCM A;  1EEN A;  1Q6J A;  4DGP A;  2CM2 A;  4RDD A;  4MBB A;  3D1Q A;  1ONY A;  4QUM A;  2BGD A;  2JJD A;  5BX1 A;  2G6Z A;  2I6P A;  2F6Z A;  2HC2 A;  1OEM X;  3OLR A;  2CM7 A;  1Q6S A;  2ZN7 A;  1L8G A;  1Q6M A;  2F71 A;  2H4K A;  4Y14 A;  2DXP A;  3AWE A;  3ZMP A;  2NT2 A;  4YR8 B;  1G1H A;  4QBE A;  3S3K A;  4TVV A;  2GP0 A;  4OHI A;  1YWF A;  3V0G A;  1BZJ A;  2H4V A;  5KA3 A;  1YZ4 A;  2GWO A;  3D9C A;  2IMG A;  2CNF A;  2B49 A;  5KA7 A;  2QDM A;  2B07 A;  2QEP A;  5K25 A;  5IBM A;  1A5Y A;  3D42 A;  3QCK A;  3QKP A;  4NND A;  4WU3 A;  3CWE A;  4OHD A;  2VEU A;  1GWZ A;  3I36 A;  1PYN A;  2F6T A;  4ICZ A;  4BJO A;  4BPC A;  5KAD A;  4JMJ A;  5EHR A;  1Q6T A;  2J16 A;  1YGR A;  4NYH A;  1NWE A;  1XXP A;  4S0G A;  1P15 A;  5K22 A;  4DGX A;  3N0A A;  3S4O A;  2P4D A;  4RI5 A;  3QCB A;  2NTA A;  3GXG A;  2M3V A;  3BRH A;  3QKQ A;  5GTJ A;  2B3O A;  2OC3 A;  4R0T A;  2PT0 A;  3D1H A;  4NWF A;  2NLK A;  2I42 A;  2HNP A;  4JNB A;  1KAV A;  4RH5 A;  1YTN A;  4OHE A;  1ONZ A;  2VEY A;  1PXH A;  1RXD A;  3ZMQ A;  4GWF A;  1KAK A;  2F6W A;  2CJZ A;  2AZR A;  2OUD A;  1I9S A;  2F70 A;  4QAP A;  2QBQ A;  4PYH A;  4OHL A;  2I4E A;  4HRF A;  5K9V A;  4QBW A;  4J51 A;  1WRM A;  2FJM A;  1M3G A;  4YAA A;  4ERC A;  2I5X A;  2QDC A;  2QDP A;  2QCJ A;  5EHP A;  5BUG A;  3V0J A;  1EEO A;  1X24 A;  1WCH A;  3F41 A;  2I3R A;  5K23 A;  1Q1M A;  4QAH A;  1YFO A;  2F6Y A;  2HB1 A;  3MOZ A;  2HXP A;  2MBC A;  2PSZ A;  2VEX A;  2E0T A;  2CNI A;  3RO1 A;  2I6I A;  3V0D A;  4Z6B A;  4R30 A;  5KAC A;  1YTW A;  2H4G A;  1C87 A;  2NZ6 A;  2I6M A;  2I6O A;  3V0H A;  4GE5 A;  4WTY A;  1RPM A;  3NME A;  3O4U A;  5KAB A;  4GS0 A;  2F6F A;  3S3F A;  3SME A;  2HC1 A;  1AAX A;  2FH7 A;  4I8N A;  2I6J A;  3ZM0 A;  4KYQ A;  3SR9 A;  5K24 A;  2B4O A;  1G1G A;  3EB1 A;  1OEV A;  3LJ8 A;  4GRY A;  4RI4 A;  4GFU A;  1OES A;  3OMH A;  2AHS A;  1G7G A;  2CM8 A;  4GE2 A;  1OET A;  1J4X A;  2ESB A;  2R0B A;  2Q47 A;  2PA5 A;  1PTV A;  3QCM A;  3BM8 A;  1G1F A;  3A5J A;  3MMJ A;  4GFV A;  2HY3 A;  1PA9 A;  2QBR A;  1PH0 A;  2H03 A;  3CM3 A;  2VEV A;  4NX8 A;  4R0S A;  4WU2 A;  2QBP A;  1ZZW A;  1T4J A;  3QCI A;  2H02 A;  1T49 A;  2PBN A;  1LYV A;  2NV5 A;  2PQ5 A;  3MOW A;  2C46 A;  2FJN A;  1NZ7 A;  2PI7 A;  2I4G A;  3I7Z A;  1NO6 A;  3F99 A;  2CMB A;  1MKP A;  3ZV2 A;  3AWG A;  3RGQ A;  5AWX A;  5MMZ B;  1WAX A;  2CMC A;  1PTU A;  1YTS A;  2NT7 A;  1NL9 A;  1C83 A;  5BZZ A;  2A8B A;  2YDU A;  4D3R A;  2BGE A;  1Q6N A;  2J17 A;  4H34 A;  2F46 A;  1I57 A;  1YPT A;  3AWF A;  1L8K A;  2I4H A;  2H04 A;  1SUG A;  4HJP A;  5IBS A;  3RGO A;  5M43 A;  3QCG A;  1ZCK A;  5KA2 A;  4AZ1 A;  3O4T A;  3D44 A;  1FPR A;  1C85 A;  5KA4 A;  2BIJ A;  2B4S A;  2HVL A;  1PTY A;  1BZH A;  2CNH A;  2P6X A;  2QCT A;  5K9W A;  2ZMM A;  2I3U A;  3V0I A;  1FQ1 A;  1XM2 A;  5I6V A;  1R6H A;  4QUN A;  1XXV A;  4PVG A;  1C88 A;  3B7O A;  1OEU A;  2CFV A;  3QCJ A;  1VHR A;  3ZM3 A;  4HJQ A;  4ZN5 A;  3A5K A;  3U96 A;  5KAA A;  2B4U A;  2CNG A;  4B04 A;  3I80 A;  4NWG A;  1I9T A;  1PTT A;  3BLU A;  3BLT A;  4OHH A;  1C86 A;  3O4S A;  3S4E A;  2CMA A;  1OHE A;  4KYR A;  5J8R A;  2B4P A;  3PS5 A;  4RHG A;  4WOH A;  1ZC0 A;  3M4U A;  3H2X A;  1GFY A;  1YN9 A;  1G4U S;  3D1O A;  2OOQ A;  1D5R A;  3QCN A;  4JMK A;  4GRZ A;  1PA1 A;  3S3H A;  4ZRT A;  5HDE A;  1NNY A;  1LQF A;  1G7F A;  2VEW A;  4Y2E A;  4ZI4 A;  1NWL A;  2CM3 A;  1QXK A;  2Y2F A;  2Q05 A;  4D3Q A;  2RF6 A;  3S3E A;  3RZ2 A;  1G4W R;  1OHD A;  1T48 A;  5KA8 A;  1U26 A;  3EMU A;  4KI9 A;  2BZL A;  1V3A A;  2WGP A;  4RH9 A;  4RKK A;  3O3L A;  1YGU A;  2SHP A;  2OZ5 A;  2Y96 A;  5LXQ B;  5KA0 A;  3EAX A;  1ZCL A;  2QBS A;  2GJT A;  3O5X A;  4D3P A;  1LAR A;  5KA9 A;  2I1Y A;  3EU0 A;  3V0F A;  3GXH A;  3QCF A;  1ECV A;  3F9A A;  2I75 A;  2A3K A;  1XRI A;  2CNE A;  1OEO X;  4IKC A;  2BV5 A;  2C7S A;  1U24 A;  3ZM2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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