4Y2EA

Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (c232s)
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
146
structure length
146
Chain Sequence
AFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 7
total genus 58
structure length 146
sequence length 146
chains with identical sequence B, C, D
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2015-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4y2eA00
2VEXA 1YZ4A 4WU2A 2G6ZA 2E0TA 3V0EA 1C85A 3ZM3A 2GJTA 3S3EA 5EHRA 2CMCA 4GRYA 4MBBA 2AZRA 2F6FA 1BZJA 5MMZB 1YGRA 4R0SA 2HB1A 1G1FA 2I75A 3OLRA 1T49A 2I6JA 4OHLA 4YR8B 5KA7A 1Q1MA 1ZCLA 2PI7A 1YGUA 4RDDA 3O4SA 1PA1A 1M3GA 3BRHA 1C86A 2CMAA 2QDPA 3I7ZA 1BZCA 1WAXA 1XM2A 2J16B 2R0BA 1ONYA 3AWGA 1A5YA 2FJNA 3F99A 3QCCA 2BGDA 2CNFA 3A5JA 3QCDA 3ZMPA 1ECVA 2BIJA 3O4TA 1YFOA 3U96A 3D1HA 5KAAA 3AWEA 2DXPA 1ONZA 2I6PA 3RGQA 1NNYA 2G59A 4GE2A 1OHCA 2B49A 2GP0A 2I42A 3V0FA 3PS5A 3ZM0A 4WTYA 1EEOA 4D3RA 3H2XA 2H4VA 1QZ0A 3F9BA 2I6IA 1OEOX 3S4OA 3V0HA 2PSZA 3BLUA 3RGOA 2VEYA 4OHEA 5BZXA 5KA0A 2FJMA 4PYHA 2I3UA 5IBMA 1YTNA 1PTVA 4KI9A 4JBCA 2F6ZA 3QCBA 1PTYA 4HJPA 4I8NA 4WOHA 2BZLA 3EAXA 1OHDA 4NYHA 1FQ1A 1LARA 5EHPA 4OHIA 1XXPA 2QEPA 2F6VA 1PXHA 4QBEA 2NTAA 1PH0A 2H02A 2HCMA 2J16A 4H34A 3AWFA 2YDUA 5AWXA 3S4EA 2VEWA 2HY3A 2ZN7A 1YTSA 2M3VA 1I9SA 2PA5A 4KYQA 2HNQA 1NO6A 2QBSA 3NMEA 4NWFA 3V0IA 3B7OA 1G1GA 4QUNA 1EENA 1FPRA 4ERCA 1Q6SA 2OOQA 2MBCA 2A3KA 4OHHA 1LYVA 2H03A 4QUMA 3QCGA 1ZZWA 2VEVA 4R0TA 5K24A 2P6XA 3D42A 3F41A 2CM7A 1X24A 5KA3A 2QCJA 4NNDA 1C83A 1OESA 2B3OA 3EMUA 2PBNA 3QCEA 1RPMA 5BZZA 4Y14A 3MOZA 4D3QA 2B4SA 3A5KA 2CM8A 2HNPA 5K25A 1PTTA 4HJQA 5HDEA 2H4KA 5KA8A 4GRZA 4NWGA 2QCTA 5KABA 4JMKA 4S0GA 2CM3A 2OZ5A 2B4UA 2QBRA 5KA1A 4NX8A 2F46A 2AHSA 2CNGA 2RF6A 4GFVA 1T4JA 4R30A 1NWLA 1T48A 4IKCA 1LQFA 5KACA 1JLNA 2QBPA 1JF7A 3O5XA 3D1QA 2J17A 2ZMMA 1L8GA 1PYNA 3QCHA 1GWZA 1U25A 1OEMX 1G7GA 2H04A 4RH5A 3GXHA 3QKQA 4Y2EA 2WGPA 5IBSA 4QAHA 3CM3A 3ZMQA 4D3PA 1YTWA 2NLKA 4RHGA 1C88A 5KA9A 1NWEA 2JJDA 5K22A 3QKPA 3F81A 3OMHA 1WRMA 1C87A 2I5XA 4Z6BA 1V3AA 4BPCA 3SR9A 1XXVA 5KA2A 2F70A 2GWOA 5I6VA 1I57A 1NZ7A 5BX1A 3V0DA 1RXDA 1PA9A 1YN9A 2ESBA 2B07A 1Q6PA 3D9CA 4ICZA 3M4UA 1Q6MA 2QDMA 4GS0A 3SMEA 3QCFA 3D44A 2I6OA 2F6YA 3N0AA 5M43A 1YPTA 1L8KA 2B4PA 3QCKA 5KADA 1SUGA 1ZCKA 2BGEA 2CNIA 2NT2A 2B4OA 4RH9A 3BM8A 3CWEA 1I9TA 2Y2FA 5K9VA 5BUGA 3S3KA 4AZ1A 5K9WA 2HC2A 3F9AA 3I80A 4JNBA 1OEUA 4YAAA 2CFVA 3GXGA 3O3LA 2PQ5A 1XRIA 2CNHA 2F6TA 2CMBA 2OC3A 1MKPA 3QCIA 4BJOA 1OEVA 2HXPA 1Q6NA 4ZN5A 1VHRA 1PTUA 3MOWA 2NV5A 1GFYA 4RI5A 3EU0A 4TVVA 2CM2A 2PT0A 3I36A 3EB1A 4H1OA 1C84A 2A8BA 4DGXA 3QCMA 2QDCA 2HC1A 4PVGA 3D1OA 3RO1A 2F6WA 2C7SA 4ZRTA 2I6MA 3V0JA 2HVLA 4J51A 2SHPA 1FPZA 3QCNA 4ZI4A 2I4HA 3ZV2A 2F71A 3QCJA 1AAXA 1QXKA 4KYRA 4RKKA 4QBWA 2Q47A 3QCLA 2VEUA 1U24A 5GTJA 1OHEA 3ZM2A 4GFUA 1ZC0A 4GE6A 2Y96A 4GE5A 5K23A 2I3RA 1BZHA 3ZM1A 1G1HA 1R6HA 1OETA 2I4GA 1NL9A 1U26A 3O4UA 2BV5A 1Q6JA 2OUDA 5LXQB 2QBQA 1KAKA 4DGPA 3S3FA 3BLTA 4QAPA 3LJ8A 1J4XA 5J8RA 3RZ2A 1KAVA 4GWFA 2FH7A 1P15A 4HRFA 2C46A 2I1YA 5KA4A 4OHDA 1WCHA 1XBOA 1D5RA 4RI4A 3EZZA 2IMGA 1YWFA 2CJZA 2CNEA 1G4WR 4WU3A 4B04A 3MMJA 2H4GA 1G4US 2NZ6A 2Q05A 2P4DA 3V0GA 1G7FA 2NT7A 1Q6TA 2I4EA 4JMJA 3S3HA
chains in the Genus database with same CATH superfamily
2VEXA 1YZ4A 4WU2A 2G6ZA 2E0TA 3V0EA 1C85A 3ZM3A 2GJTA 3S3EA 5EHRA 2CMCA 4GRYA 4MBBA 2AZRA 2F6FA 1BZJA 5MMZB 1YGRA 4R0SA 2HB1A 1G1FA 2Y1OA 2I75A 3OLRA 1T49A 2I6JA 4OHLA 4YR8B 5KA7A 1Q1MA 1ZCLA 2F00A 2PI7A 1YGUA 4RDDA 3O4SA 1PA1A 1M3GA 3BRHA 1C86A 2CMAA 2QDPA 3I7ZA 1BZCA 1WAXA 2VORA 2Y66A 1XM2A 2J16B 2R0BA 5A5EA 1ONYA 3AWGA 1A5YA 2FJNA 3F99A 3QCCA 2BGDA 2CNFA 3A5JA 3QCDA 3ZMPA 1ECVA 1W78A 2BIJA 3O4TA 1YFOA 3U96A 2GCAA 3D1HA 5KAAA 3AWEA 2DXPA 1ONZA 2I6PA 3RGQA 1E8CA 2VOSA 1NNYA 2G59A 4GE2A 1OHCA 2B49A 2GP0A 4C13A 2I42A 3V0FA 3PS5A 3ZM0A 3NRSA 4WTYA 1EEOA 4D3RA 3H2XA 2H4VA 3N2AA 1QZ0A 3F9BA 2I6IA 1OEOX 2UAGA 3S4OA 3V0HA 2PSZA 3BLUA 3RGOA 2VEYA 4OHEA 5BZXA 5KA0A 2FJMA 2GC6A 2Y67A 4PYHA 2I3UA 5IBMA 1YTNA 1PTVA 4KI9A 4JBCA 2F6ZA 2VTEA 3QCBA 1PTYA 4HJPA 4I8NA 4WOHA 2BZLA 2VTDA 1OHDA 3EAXA 4NYHA 1FQ1A 1LARA 5EHPA 4OHIA 1XXPA 2QEPA 2F6VA 1PXHA 4QBEA 2NTAA 1PH0A 2H02A 2HCMA 2J16A 2UUPA 3AWFA 4H34A 2YDUA 2JFGA 5AWXA 3S4EA 2VEWA 2HY3A 2ZN7A 1YTSA 2AM1A 2M3VA 1I9SA 2PA5A 4KYQA 2HNQA 1NO6A 2QBSA 3NMEA 4NWFA 3V0IA 3B7OA 1E0DA 1G1GA 4QUNA 1EENA 1FPRA 4ERCA 1Q6SA 2OOQA 2MBCA 2A3KA 4OHHA 1LYVA 2WTZA 2H03A 4QUMA 3QCGA 1ZZWA 2VEVA 4R0TA 5K24A 2P6XA 3D42A 3F41A 2CM7A 1X24A 5KA3A 2QCJA 4NNDA 1C83A 1OESA 2B3OA 3EMUA 2PBNA 3QCEA 1RPMA 5BZZA 4Y14A 3MOZA 4D3QA 2B4SA 2GCBA 3A5KA 2CM8A 2HNPA 2JFFA 5K25A 1PTTA 4HJQA 5HDEA 2H4KA 5KA8A 4GRZA 1P3DA 4NWGA 4QDIA 2QCTA 5KABA 4JMKA 4S0GA 2CM3A 2OZ5A 2B4UA 2QBRA 5KA1A 4NX8A 2F46A 2AHSA 2CNGA 2RF6A 4GFVA 4CVMA 1T4JA 4R30A 1NWLA 3HN7A 1JBVA 3PYZA 1T48A 4IKCA 1LQFA 5KACA 1JLNA 2QBPA 1JF7A 3O5XA 3D1QA 1O5ZA 2J17A 1L8GA 2ZMMA 1PYNA 3QCHA 1GWZA 1U25A 1OEMX 1G7GA 2H04A 4RH5A 3GXHA 3QKQA 4Y2EA 2WGPA 5IBSA 4QAHA 3CM3A 3ZMQA 4D3PA 1FGSA 1YTWA 2NLKA 4RHGA 1C88A 5KA9A 1NWEA 2JJDA 5K22A 2JFHA 4BUCA 3QKPA 3F81A 3OMHA 1WRMA 2XJAA 1C87A 2I5XA 4Z6BA 2Y68A 1V3AA 4BPCA 3SR9A 1XXVA 1W7KA 5KA2A 2F70A 2GWOA 5I6VA 1GQYA 1I57A 1NZ7A 5BX1A 3V0DA 1RXDA 1PA9A 1YN9A 2ESBA 2B07A 1Q6PA 3D9CA 4ICZA 3M4UA 1Q6MA 2QDMA 4GS0A 3SMEA 3QCFA 3D44A 3LK7A 2I6OA 1EEHA 2F6YA 3N0AA 5M43A 1YPTA 1L8KA 2B4PA 3QCKA 5KADA 1SUGA 1ZCKA 2BGEA 2CNIA 2NT2A 3QCZA 2B4OA 4RH9A 3BM8A 3CWEA 1I9TA 2Y2FA 5K9VA 5BUGA 3S3KA 4AZ1A 5K9WA 2HC2A 3F9AA 3I80A 4JNBA 1OEUA 4YAAA 2CFVA 3GXGA 3O3LA 5A5FA 2PQ5A 2X5OA 1XRIA 2CNHA 2F6TA 2CMBA 2OC3A 1MKPA 3QCIA 4BJOA 1OEVA 2HXPA 1Q6NA 4ZN5A 1VHRA 1PTUA 3MOWA 2NV5A 1GFYA 4RI5A 3EU0A 4TVVA 2CM2A 2PT0A 3I36A 3EB1A 4H1OA 1C84A 2A8BA 4DGXA 3QCMA 4CVLA 2QDCA 2HC1A 4PVGA 3D1OA 3RO1A 2F6WA 2C7SA 4ZRTA 4C12A 2I6MA 3V0JA 2HVLA 1UAGA 4J51A 2SHPA 2XPCA 1FPZA 3MVNA 3QCNA 3ZL8A 4ZI4A 2I4HA 3ZV2A 4HV4A 2WJPA 2F71A 3QCJA 1AAXA 1JBWA 1QXKA 4KYRA 4RKKA 4QBWA 2Q47A 3QCLA 2VEUA 1U24A 5GTJA 1OHEA 3ZM2A 4GFUA 1ZC0A 4GE6A 2Y96A 4GE5A 4UAGA 5K23A 2I3RA 1BZHA 3ZM1A 1G1HA 2GC5A 4QF5A 1R6HA 1OETA 2I4GA 4CVKA 1NL9A 1U26A 3O4UA 2BV5A 2AM2A 1Q6JA 2OUDA 5LXQB 2QBQA 1KAKA 4DGPA 3S3FA 3ZM5A 3BLTA 4QAPA 3LJ8A 1J4XA 5J8RA 3RZ2A 1KAVA 4GWFA 2FH7A 1P15A 4HRFA 2C46A 2I1YA 5KA4A 1P31A 4OHDA 1WCHA 1XBOA 1D5RA 3UAGA 4RI4A 1GG4A 3EZZA 2IMGA 1YWFA 2CJZA 2CNEA 3ZM6A 1G4WR 4WU3A 4B04A 3MMJA 2H4GA 1G4US 2NZ6A 2Q05A 2P4DA 4ZIYA 3V0GA 4BUBA 2UUOA 1J6UA 1G7FA 2NT7A 1Q6TA 1GQQA 2I4EA 4JMJA 3S3HA
chains in the Genus database with same CATH topology
2VEXA 1YZ4A 4WU2A 2G6ZA 2E0TA 3V0EA 1C85A 3ZM3A 2GJTA 3S3EA 5EHRA 2CMCA 4GRYA 4MBBA 2AZRA 2F6FA 1BZJA 5MMZB 1YGRA 4R0SA 2HB1A 1G1FA 2I75A 3OLRA 1T49A 2I6JA 4OHLA 4YR8B 5KA7A 1Q1MA 1ZCLA 2PI7A 1YGUA 4RDDA 3O4SA 1PA1A 1M3GA 3BRHA 1C86A 2CMAA 2QDPA 3I7ZA 1BZCA 1WAXA 1XM2A 2J16B 2R0BA 1ONYA 3AWGA 1A5YA 2FJNA 3F99A 3QCCA 2BGDA 2CNFA 3A5JA 3QCDA 3ZMPA 1ECVA 2BIJA 3O4TA 1YFOA 3U96A 3D1HA 5KAAA 3AWEA 2DXPA 1ONZA 2I6PA 3RGQA 1NNYA 2G59A 4GE2A 1OHCA 2B49A 2GP0A 2I42A 3V0FA 3PS5A 3ZM0A 4WTYA 1EEOA 4D3RA 3H2XA 2H4VA 1QZ0A 3F9BA 2I6IA 1OEOX 3S4OA 3V0HA 2PSZA 3BLUA 3RGOA 2VEYA 4OHEA 5BZXA 5KA0A 2FJMA 4PYHA 2I3UA 5IBMA 1YTNA 1PTVA 4KI9A 4JBCA 2F6ZA 3QCBA 1PTYA 4HJPA 4I8NA 4WOHA 2BZLA 3EAXA 1OHDA 4NYHA 1FQ1A 1LARA 5EHPA 4OHIA 1XXPA 2QEPA 2F6VA 1PXHA 4QBEA 2NTAA 1PH0A 2H02A 2HCMA 2J16A 4H34A 3AWFA 2YDUA 5AWXA 3S4EA 2VEWA 2HY3A 2ZN7A 1YTSA 2M3VA 1I9SA 2PA5A 4KYQA 2HNQA 1NO6A 2QBSA 3NMEA 4NWFA 3V0IA 3B7OA 1G1GA 4QUNA 1EENA 1FPRA 4ERCA 1Q6SA 2OOQA 2MBCA 2A3KA 4OHHA 1LYVA 2H03A 4QUMA 3QCGA 1ZZWA 2VEVA 4R0TA 5K24A 2P6XA 3D42A 3F41A 2CM7A 1X24A 5KA3A 2QCJA 4NNDA 1C83A 1OESA 2B3OA 3EMUA 2PBNA 3QCEA 1RPMA 5BZZA 4Y14A 3MOZA 4D3QA 2B4SA 3A5KA 2CM8A 2HNPA 5K25A 1PTTA 4HJQA 5HDEA 2H4KA 5KA8A 4GRZA 4NWGA 2QCTA 5KABA 4JMKA 4S0GA 2CM3A 2OZ5A 2B4UA 2QBRA 5KA1A 4NX8A 2F46A 2AHSA 2CNGA 2RF6A 4GFVA 1T4JA 4R30A 1NWLA 1T48A 4IKCA 1LQFA 5KACA 1JLNA 2QBPA 1JF7A 3O5XA 3D1QA 2J17A 2ZMMA 1L8GA 1PYNA 3QCHA 1GWZA 1U25A 1OEMX 1G7GA 2H04A 4RH5A 3GXHA 3QKQA 4Y2EA 2WGPA 5IBSA 4QAHA 3CM3A 3ZMQA 4D3PA 1YTWA 2NLKA 4RHGA 1C88A 5KA9A 1NWEA 2JJDA 5K22A 3QKPA 3F81A 3OMHA 1WRMA 1C87A 2I5XA 4Z6BA 1V3AA 4BPCA 3SR9A 1XXVA 5KA2A 2F70A 2GWOA 5I6VA 1I57A 1NZ7A 5BX1A 3V0DA 1RXDA 1PA9A 1YN9A 2ESBA 2B07A 1Q6PA 3D9CA 4ICZA 3M4UA 1Q6MA 2QDMA 4GS0A 3SMEA 3QCFA 3D44A 2I6OA 2F6YA 3N0AA 5M43A 1YPTA 1L8KA 2B4PA 3QCKA 5KADA 1SUGA 1ZCKA 2BGEA 2CNIA 2NT2A 2B4OA 4RH9A 3BM8A 3CWEA 1I9TA 2Y2FA 5K9VA 5BUGA 3S3KA 4AZ1A 5K9WA 2HC2A 3F9AA 3I80A 4JNBA 1OEUA 4YAAA 2CFVA 3GXGA 3O3LA 2PQ5A 1XRIA 2CNHA 2F6TA 2CMBA 2OC3A 1MKPA 3QCIA 4BJOA 1OEVA 2HXPA 1Q6NA 4ZN5A 1VHRA 1PTUA 3MOWA 2NV5A 1GFYA 4RI5A 3EU0A 4TVVA 2CM2A 2PT0A 3I36A 3EB1A 4H1OA 1C84A 2A8BA 4DGXA 3QCMA 2QDCA 2HC1A 4PVGA 3D1OA 3RO1A 2F6WA 2C7SA 4ZRTA 2I6MA 3V0JA 2HVLA 4J51A 2SHPA 1FPZA 3QCNA 4ZI4A 2I4HA 3ZV2A 2F71A 3QCJA 1AAXA 1QXKA 4KYRA 4RKKA 4QBWA 2Q47A 3QCLA 2VEUA 1U24A 5GTJA 1OHEA 3ZM2A 4GFUA 1ZC0A 4GE6A 2Y96A 4GE5A 5K23A 2I3RA 1BZHA 3ZM1A 1G1HA 1R6HA 1OETA 2I4GA 1NL9A 1U26A 3O4UA 2BV5A 1Q6JA 2OUDA 5LXQB 2QBQA 1KAKA 4DGPA 3S3FA 3BLTA 4QAPA 3LJ8A 1J4XA 5J8RA 3RZ2A 1KAVA 4GWFA 2FH7A 1P15A 4HRFA 2C46A 2I1YA 5KA4A 4OHDA 1WCHA 1XBOA 1D5RA 4RI4A 3EZZA 2IMGA 1YWFA 2CJZA 2CNEA 1G4WR 4WU3A 4B04A 3MMJA 2H4GA 1G4US 2NZ6A 2Q05A 2P4DA 3V0GA 1G7FA 2NT7A 1Q6TA 2I4EA 4JMJA 3S3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VEX A;  1YZ4 A;  4WU2 A;  2G6Z A;  2E0T A;  3V0E A;  1C85 A;  3ZM3 A;  2GJT A;  3S3E A;  5EHR A;  2CMC A;  4GRY A;  4MBB A;  2AZR A;  2F6F A;  1BZJ A;  5MMZ B;  1YGR A;  4R0S A;  2HB1 A;  1G1F A;  2I75 A;  3OLR A;  1T49 A;  2I6J A;  4OHL A;  4YR8 B;  5KA7 A;  1Q1M A;  1ZCL A;  2PI7 A;  1YGU A;  4RDD A;  3O4S A;  1PA1 A;  1M3G A;  3BRH A;  1C86 A;  2CMA A;  2QDP A;  3I7Z A;  1BZC A;  1WAX A;  1XM2 A;  2J16 B;  2R0B A;  1ONY A;  3AWG A;  1A5Y A;  2FJN A;  3F99 A;  3QCC A;  2BGD A;  2CNF A;  3A5J A;  3QCD A;  3ZMP A;  1ECV A;  2BIJ A;  3O4T A;  1YFO A;  3U96 A;  3D1H A;  5KAA A;  3AWE A;  2DXP A;  1ONZ A;  2I6P A;  3RGQ A;  1NNY A;  2G59 A;  4GE2 A;  1OHC A;  2B49 A;  2GP0 A;  2I42 A;  3V0F A;  3PS5 A;  3ZM0 A;  4WTY A;  1EEO A;  4D3R A;  3H2X A;  2H4V A;  1QZ0 A;  3F9B A;  2I6I A;  1OEO X;  3S4O A;  3V0H A;  2PSZ A;  3BLU A;  3RGO A;  2VEY A;  4OHE A;  5BZX A;  5KA0 A;  2FJM A;  4PYH A;  2I3U A;  5IBM A;  1YTN A;  1PTV A;  4KI9 A;  4JBC A;  2F6Z A;  3QCB A;  1PTY A;  4HJP A;  4I8N A;  4WOH A;  2BZL A;  3EAX A;  1OHD A;  4NYH A;  1FQ1 A;  1LAR A;  5EHP A;  4OHI A;  1XXP A;  2QEP A;  2F6V A;  1PXH A;  4QBE A;  2NTA A;  1PH0 A;  2H02 A;  2HCM A;  2J16 A;  4H34 A;  3AWF A;  2YDU A;  5AWX A;  3S4E A;  2VEW A;  2HY3 A;  2ZN7 A;  1YTS A;  2M3V A;  1I9S A;  2PA5 A;  4KYQ A;  2HNQ A;  1NO6 A;  2QBS A;  3NME A;  4NWF A;  3V0I A;  3B7O A;  1G1G A;  4QUN A;  1EEN A;  1FPR A;  4ERC A;  1Q6S A;  2OOQ A;  2MBC A;  2A3K A;  4OHH A;  1LYV A;  2H03 A;  4QUM A;  3QCG A;  1ZZW A;  2VEV A;  4R0T A;  5K24 A;  2P6X A;  3D42 A;  3F41 A;  2CM7 A;  1X24 A;  5KA3 A;  2QCJ A;  4NND A;  1C83 A;  1OES A;  2B3O A;  3EMU A;  2PBN A;  3QCE A;  1RPM A;  5BZZ A;  4Y14 A;  3MOZ A;  4D3Q A;  2B4S A;  3A5K A;  2CM8 A;  2HNP A;  5K25 A;  1PTT A;  4HJQ A;  5HDE A;  2H4K A;  5KA8 A;  4GRZ A;  4NWG A;  2QCT A;  5KAB A;  4JMK A;  4S0G A;  2CM3 A;  2OZ5 A;  2B4U A;  2QBR A;  5KA1 A;  4NX8 A;  2F46 A;  2AHS A;  2CNG A;  2RF6 A;  4GFV A;  1T4J A;  4R30 A;  1NWL A;  1T48 A;  4IKC A;  1LQF A;  5KAC A;  1JLN A;  2QBP A;  1JF7 A;  3O5X A;  3D1Q A;  2J17 A;  2ZMM A;  1L8G A;  1PYN A;  3QCH A;  1GWZ A;  1U25 A;  1OEM X;  1G7G A;  2H04 A;  4RH5 A;  3GXH A;  3QKQ A;  4Y2E A;  2WGP A;  5IBS A;  4QAH A;  3CM3 A;  3ZMQ A;  4D3P A;  1YTW A;  2NLK A;  4RHG A;  1C88 A;  5KA9 A;  1NWE A;  2JJD A;  5K22 A;  3QKP A;  3F81 A;  3OMH A;  1WRM A;  1C87 A;  2I5X A;  4Z6B A;  1V3A A;  4BPC A;  3SR9 A;  1XXV A;  5KA2 A;  2F70 A;  2GWO A;  5I6V A;  1I57 A;  1NZ7 A;  5BX1 A;  3V0D A;  1RXD A;  1PA9 A;  1YN9 A;  2ESB A;  2B07 A;  1Q6P A;  3D9C A;  4ICZ A;  3M4U A;  1Q6M A;  2QDM A;  4GS0 A;  3SME A;  3QCF A;  3D44 A;  2I6O A;  2F6Y A;  3N0A A;  5M43 A;  1YPT A;  1L8K A;  2B4P A;  3QCK A;  5KAD A;  1SUG A;  1ZCK A;  2BGE A;  2CNI A;  2NT2 A;  2B4O A;  4RH9 A;  3BM8 A;  3CWE A;  1I9T A;  2Y2F A;  5K9V A;  5BUG A;  3S3K A;  4AZ1 A;  5K9W A;  2HC2 A;  3F9A A;  3I80 A;  4JNB A;  1OEU A;  4YAA A;  2CFV A;  3GXG A;  3O3L A;  2PQ5 A;  1XRI A;  2CNH A;  2F6T A;  2CMB A;  2OC3 A;  1MKP A;  3QCI A;  4BJO A;  1OEV A;  2HXP A;  1Q6N A;  4ZN5 A;  1VHR A;  1PTU A;  3MOW A;  2NV5 A;  1GFY A;  4RI5 A;  3EU0 A;  4TVV A;  2CM2 A;  2PT0 A;  3I36 A;  3EB1 A;  4H1O A;  1C84 A;  2A8B A;  4DGX A;  3QCM A;  2QDC A;  2HC1 A;  4PVG A;  3D1O A;  3RO1 A;  2F6W A;  2C7S A;  4ZRT A;  2I6M A;  3V0J A;  2HVL A;  4J51 A;  2SHP A;  1FPZ A;  3QCN A;  4ZI4 A;  2I4H A;  3ZV2 A;  2F71 A;  3QCJ A;  1AAX A;  1QXK A;  4KYR A;  4RKK A;  4QBW A;  2Q47 A;  3QCL A;  2VEU A;  1U24 A;  5GTJ A;  1OHE A;  3ZM2 A;  4GFU A;  1ZC0 A;  4GE6 A;  2Y96 A;  4GE5 A;  5K23 A;  2I3R A;  1BZH A;  3ZM1 A;  1G1H A;  1R6H A;  1OET A;  2I4G A;  1NL9 A;  1U26 A;  3O4U A;  2BV5 A;  1Q6J A;  2OUD A;  5LXQ B;  2QBQ A;  1KAK A;  4DGP A;  3S3F A;  3BLT A;  4QAP A;  3LJ8 A;  1J4X A;  5J8R A;  3RZ2 A;  1KAV A;  4GWF A;  2FH7 A;  1P15 A;  4HRF A;  2C46 A;  2I1Y A;  5KA4 A;  4OHD A;  1WCH A;  1XBO A;  1D5R A;  4RI4 A;  3EZZ A;  2IMG A;  1YWF A;  2CJZ A;  2CNE A;  1G4W R;  4WU3 A;  4B04 A;  3MMJ A;  2H4G A;  1G4U S;  2NZ6 A;  2Q05 A;  2P4D A;  3V0G A;  1G7F A;  2NT7 A;  1Q6T A;  2I4E A;  4JMJ A;  3S3H A; 
#chains in the Genus database with same CATH topology
 2VEX A;  1YZ4 A;  4WU2 A;  2G6Z A;  2E0T A;  3V0E A;  1C85 A;  3ZM3 A;  2GJT A;  3S3E A;  5EHR A;  2CMC A;  4GRY A;  4MBB A;  2AZR A;  2F6F A;  1BZJ A;  5MMZ B;  1YGR A;  4R0S A;  2HB1 A;  1G1F A;  2Y1O A;  2I75 A;  3OLR A;  1T49 A;  2I6J A;  4OHL A;  4YR8 B;  5KA7 A;  1Q1M A;  1ZCL A;  2F00 A;  2PI7 A;  1YGU A;  4RDD A;  3O4S A;  1PA1 A;  1M3G A;  3BRH A;  1C86 A;  2CMA A;  2QDP A;  3I7Z A;  1BZC A;  1WAX A;  2VOR A;  2Y66 A;  1XM2 A;  2J16 B;  2R0B A;  5A5E A;  1ONY A;  3AWG A;  1A5Y A;  2FJN A;  3F99 A;  3QCC A;  2BGD A;  2CNF A;  3A5J A;  3QCD A;  3ZMP A;  1ECV A;  1W78 A;  2BIJ A;  3O4T A;  1YFO A;  3U96 A;  2GCA A;  3D1H A;  5KAA A;  3AWE A;  2DXP A;  1ONZ A;  2I6P A;  3RGQ A;  1E8C A;  2VOS A;  1NNY A;  2G59 A;  4GE2 A;  1OHC A;  2B49 A;  2GP0 A;  4C13 A;  2I42 A;  3V0F A;  3PS5 A;  3ZM0 A;  3NRS A;  4WTY A;  1EEO A;  4D3R A;  3H2X A;  2H4V A;  3N2A A;  1QZ0 A;  3F9B A;  2I6I A;  1OEO X;  2UAG A;  3S4O A;  3V0H A;  2PSZ A;  3BLU A;  3RGO A;  2VEY A;  4OHE A;  5BZX A;  5KA0 A;  2FJM A;  2GC6 A;  2Y67 A;  4PYH A;  2I3U A;  5IBM A;  1YTN A;  1PTV A;  4KI9 A;  4JBC A;  2F6Z A;  2VTE A;  3QCB A;  1PTY A;  4HJP A;  4I8N A;  4WOH A;  2BZL A;  2VTD A;  1OHD A;  3EAX A;  4NYH A;  1FQ1 A;  1LAR A;  5EHP A;  4OHI A;  1XXP A;  2QEP A;  2F6V A;  1PXH A;  4QBE A;  2NTA A;  1PH0 A;  2H02 A;  2HCM A;  2J16 A;  2UUP A;  3AWF A;  4H34 A;  2YDU A;  2JFG A;  5AWX A;  3S4E A;  2VEW A;  2HY3 A;  2ZN7 A;  1YTS A;  2AM1 A;  2M3V A;  1I9S A;  2PA5 A;  4KYQ A;  2HNQ A;  1NO6 A;  2QBS A;  3NME A;  4NWF A;  3V0I A;  3B7O A;  1E0D A;  1G1G A;  4QUN A;  1EEN A;  1FPR A;  4ERC A;  1Q6S A;  2OOQ A;  2MBC A;  2A3K A;  4OHH A;  1LYV A;  2WTZ A;  2H03 A;  4QUM A;  3QCG A;  1ZZW A;  2VEV A;  4R0T A;  5K24 A;  2P6X A;  3D42 A;  3F41 A;  2CM7 A;  1X24 A;  5KA3 A;  2QCJ A;  4NND A;  1C83 A;  1OES A;  2B3O A;  3EMU A;  2PBN A;  3QCE A;  1RPM A;  5BZZ A;  4Y14 A;  3MOZ A;  4D3Q A;  2B4S A;  2GCB A;  3A5K A;  2CM8 A;  2HNP A;  2JFF A;  5K25 A;  1PTT A;  4HJQ A;  5HDE A;  2H4K A;  5KA8 A;  4GRZ A;  1P3D A;  4NWG A;  4QDI A;  2QCT A;  5KAB A;  4JMK A;  4S0G A;  2CM3 A;  2OZ5 A;  2B4U A;  2QBR A;  5KA1 A;  4NX8 A;  2F46 A;  2AHS A;  2CNG A;  2RF6 A;  4GFV A;  4CVM A;  1T4J A;  4R30 A;  1NWL A;  3HN7 A;  1JBV A;  3PYZ A;  1T48 A;  4IKC A;  1LQF A;  5KAC A;  1JLN A;  2QBP A;  1JF7 A;  3O5X A;  3D1Q A;  1O5Z A;  2J17 A;  1L8G A;  2ZMM A;  1PYN A;  3QCH A;  1GWZ A;  1U25 A;  1OEM X;  1G7G A;  2H04 A;  4RH5 A;  3GXH A;  3QKQ A;  4Y2E A;  2WGP A;  5IBS A;  4QAH A;  3CM3 A;  3ZMQ A;  4D3P A;  1FGS A;  1YTW A;  2NLK A;  4RHG A;  1C88 A;  5KA9 A;  1NWE A;  2JJD A;  5K22 A;  2JFH A;  4BUC A;  3QKP A;  3F81 A;  3OMH A;  1WRM A;  2XJA A;  1C87 A;  2I5X A;  4Z6B A;  2Y68 A;  1V3A A;  4BPC A;  3SR9 A;  1XXV A;  1W7K A;  5KA2 A;  2F70 A;  2GWO A;  5I6V A;  1GQY A;  1I57 A;  1NZ7 A;  5BX1 A;  3V0D A;  1RXD A;  1PA9 A;  1YN9 A;  2ESB A;  2B07 A;  1Q6P A;  3D9C A;  4ICZ A;  3M4U A;  1Q6M A;  2QDM A;  4GS0 A;  3SME A;  3QCF A;  3D44 A;  3LK7 A;  2I6O A;  1EEH A;  2F6Y A;  3N0A A;  5M43 A;  1YPT A;  1L8K A;  2B4P A;  3QCK A;  5KAD A;  1SUG A;  1ZCK A;  2BGE A;  2CNI A;  2NT2 A;  3QCZ A;  2B4O A;  4RH9 A;  3BM8 A;  3CWE A;  1I9T A;  2Y2F A;  5K9V A;  5BUG A;  3S3K A;  4AZ1 A;  5K9W A;  2HC2 A;  3F9A A;  3I80 A;  4JNB A;  1OEU A;  4YAA A;  2CFV A;  3GXG A;  3O3L A;  5A5F A;  2PQ5 A;  2X5O A;  1XRI A;  2CNH A;  2F6T A;  2CMB A;  2OC3 A;  1MKP A;  3QCI A;  4BJO A;  1OEV A;  2HXP A;  1Q6N A;  4ZN5 A;  1VHR A;  1PTU A;  3MOW A;  2NV5 A;  1GFY A;  4RI5 A;  3EU0 A;  4TVV A;  2CM2 A;  2PT0 A;  3I36 A;  3EB1 A;  4H1O A;  1C84 A;  2A8B A;  4DGX A;  3QCM A;  4CVL A;  2QDC A;  2HC1 A;  4PVG A;  3D1O A;  3RO1 A;  2F6W A;  2C7S A;  4ZRT A;  4C12 A;  2I6M A;  3V0J A;  2HVL A;  1UAG A;  4J51 A;  2SHP A;  2XPC A;  1FPZ A;  3MVN A;  3QCN A;  3ZL8 A;  4ZI4 A;  2I4H A;  3ZV2 A;  4HV4 A;  2WJP A;  2F71 A;  3QCJ A;  1AAX A;  1JBW A;  1QXK A;  4KYR A;  4RKK A;  4QBW A;  2Q47 A;  3QCL A;  2VEU A;  1U24 A;  5GTJ A;  1OHE A;  3ZM2 A;  4GFU A;  1ZC0 A;  4GE6 A;  2Y96 A;  4GE5 A;  4UAG A;  5K23 A;  2I3R A;  1BZH A;  3ZM1 A;  1G1H A;  2GC5 A;  4QF5 A;  1R6H A;  1OET A;  2I4G A;  4CVK A;  1NL9 A;  1U26 A;  3O4U A;  2BV5 A;  2AM2 A;  1Q6J A;  2OUD A;  5LXQ B;  2QBQ A;  1KAK A;  4DGP A;  3S3F A;  3ZM5 A;  3BLT A;  4QAP A;  3LJ8 A;  1J4X A;  5J8R A;  3RZ2 A;  1KAV A;  4GWF A;  2FH7 A;  1P15 A;  4HRF A;  2C46 A;  2I1Y A;  5KA4 A;  1P31 A;  4OHD A;  1WCH A;  1XBO A;  1D5R A;  3UAG A;  4RI4 A;  1GG4 A;  3EZZ A;  2IMG A;  1YWF A;  2CJZ A;  2CNE A;  3ZM6 A;  1G4W R;  4WU3 A;  4B04 A;  3MMJ A;  2H4G A;  1G4U S;  2NZ6 A;  2Q05 A;  2P4D A;  4ZIY A;  3V0G A;  4BUB A;  2UUO A;  1J6U A;  1G7F A;  2NT7 A;  1Q6T A;  1GQQ A;  2I4E A;  4JMJ A;  3S3H A; 
#chains in the Genus database with same CATH homology
 2VEX A;  1YZ4 A;  4WU2 A;  2G6Z A;  2E0T A;  3V0E A;  1C85 A;  3ZM3 A;  2GJT A;  3S3E A;  5EHR A;  2CMC A;  4GRY A;  4MBB A;  2AZR A;  2F6F A;  1BZJ A;  5MMZ B;  1YGR A;  4R0S A;  2HB1 A;  1G1F A;  2I75 A;  3OLR A;  1T49 A;  2I6J A;  4OHL A;  4YR8 B;  5KA7 A;  1Q1M A;  1ZCL A;  2PI7 A;  1YGU A;  4RDD A;  3O4S A;  1PA1 A;  1M3G A;  3BRH A;  1C86 A;  2CMA A;  2QDP A;  3I7Z A;  1BZC A;  1WAX A;  1XM2 A;  2J16 B;  2R0B A;  1ONY A;  3AWG A;  1A5Y A;  2FJN A;  3F99 A;  3QCC A;  2BGD A;  2CNF A;  3A5J A;  3QCD A;  3ZMP A;  1ECV A;  2BIJ A;  3O4T A;  1YFO A;  3U96 A;  3D1H A;  5KAA A;  3AWE A;  2DXP A;  1ONZ A;  2I6P A;  3RGQ A;  1NNY A;  2G59 A;  4GE2 A;  1OHC A;  2B49 A;  2GP0 A;  2I42 A;  3V0F A;  3PS5 A;  3ZM0 A;  4WTY A;  1EEO A;  4D3R A;  3H2X A;  2H4V A;  1QZ0 A;  3F9B A;  2I6I A;  1OEO X;  3S4O A;  3V0H A;  2PSZ A;  3BLU A;  3RGO A;  2VEY A;  4OHE A;  5BZX A;  5KA0 A;  2FJM A;  4PYH A;  2I3U A;  5IBM A;  1YTN A;  1PTV A;  4KI9 A;  4JBC A;  2F6Z A;  3QCB A;  1PTY A;  4HJP A;  4I8N A;  4WOH A;  2BZL A;  3EAX A;  1OHD A;  4NYH A;  1FQ1 A;  1LAR A;  5EHP A;  4OHI A;  1XXP A;  2QEP A;  2F6V A;  1PXH A;  4QBE A;  2NTA A;  1PH0 A;  2H02 A;  2HCM A;  2J16 A;  4H34 A;  3AWF A;  2YDU A;  5AWX A;  3S4E A;  2VEW A;  2HY3 A;  2ZN7 A;  1YTS A;  2M3V A;  1I9S A;  2PA5 A;  4KYQ A;  2HNQ A;  1NO6 A;  2QBS A;  3NME A;  4NWF A;  3V0I A;  3B7O A;  1G1G A;  4QUN A;  1EEN A;  1FPR A;  4ERC A;  1Q6S A;  2OOQ A;  2MBC A;  2A3K A;  4OHH A;  1LYV A;  2H03 A;  4QUM A;  3QCG A;  1ZZW A;  2VEV A;  4R0T A;  5K24 A;  2P6X A;  3D42 A;  3F41 A;  2CM7 A;  1X24 A;  5KA3 A;  2QCJ A;  4NND A;  1C83 A;  1OES A;  2B3O A;  3EMU A;  2PBN A;  3QCE A;  1RPM A;  5BZZ A;  4Y14 A;  3MOZ A;  4D3Q A;  2B4S A;  3A5K A;  2CM8 A;  2HNP A;  5K25 A;  1PTT A;  4HJQ A;  5HDE A;  2H4K A;  5KA8 A;  4GRZ A;  4NWG A;  2QCT A;  5KAB A;  4JMK A;  4S0G A;  2CM3 A;  2OZ5 A;  2B4U A;  2QBR A;  5KA1 A;  4NX8 A;  2F46 A;  2AHS A;  2CNG A;  2RF6 A;  4GFV A;  1T4J A;  4R30 A;  1NWL A;  1T48 A;  4IKC A;  1LQF A;  5KAC A;  1JLN A;  2QBP A;  1JF7 A;  3O5X A;  3D1Q A;  2J17 A;  2ZMM A;  1L8G A;  1PYN A;  3QCH A;  1GWZ A;  1U25 A;  1OEM X;  1G7G A;  2H04 A;  4RH5 A;  3GXH A;  3QKQ A;  4Y2E A;  2WGP A;  5IBS A;  4QAH A;  3CM3 A;  3ZMQ A;  4D3P A;  1YTW A;  2NLK A;  4RHG A;  1C88 A;  5KA9 A;  1NWE A;  2JJD A;  5K22 A;  3QKP A;  3F81 A;  3OMH A;  1WRM A;  1C87 A;  2I5X A;  4Z6B A;  1V3A A;  4BPC A;  3SR9 A;  1XXV A;  5KA2 A;  2F70 A;  2GWO A;  5I6V A;  1I57 A;  1NZ7 A;  5BX1 A;  3V0D A;  1RXD A;  1PA9 A;  1YN9 A;  2ESB A;  2B07 A;  1Q6P A;  3D9C A;  4ICZ A;  3M4U A;  1Q6M A;  2QDM A;  4GS0 A;  3SME A;  3QCF A;  3D44 A;  2I6O A;  2F6Y A;  3N0A A;  5M43 A;  1YPT A;  1L8K A;  2B4P A;  3QCK A;  5KAD A;  1SUG A;  1ZCK A;  2BGE A;  2CNI A;  2NT2 A;  2B4O A;  4RH9 A;  3BM8 A;  3CWE A;  1I9T A;  2Y2F A;  5K9V A;  5BUG A;  3S3K A;  4AZ1 A;  5K9W A;  2HC2 A;  3F9A A;  3I80 A;  4JNB A;  1OEU A;  4YAA A;  2CFV A;  3GXG A;  3O3L A;  2PQ5 A;  1XRI A;  2CNH A;  2F6T A;  2CMB A;  2OC3 A;  1MKP A;  3QCI A;  4BJO A;  1OEV A;  2HXP A;  1Q6N A;  4ZN5 A;  1VHR A;  1PTU A;  3MOW A;  2NV5 A;  1GFY A;  4RI5 A;  3EU0 A;  4TVV A;  2CM2 A;  2PT0 A;  3I36 A;  3EB1 A;  4H1O A;  1C84 A;  2A8B A;  4DGX A;  3QCM A;  2QDC A;  2HC1 A;  4PVG A;  3D1O A;  3RO1 A;  2F6W A;  2C7S A;  4ZRT A;  2I6M A;  3V0J A;  2HVL A;  4J51 A;  2SHP A;  1FPZ A;  3QCN A;  4ZI4 A;  2I4H A;  3ZV2 A;  2F71 A;  3QCJ A;  1AAX A;  1QXK A;  4KYR A;  4RKK A;  4QBW A;  2Q47 A;  3QCL A;  2VEU A;  1U24 A;  5GTJ A;  1OHE A;  3ZM2 A;  4GFU A;  1ZC0 A;  4GE6 A;  2Y96 A;  4GE5 A;  5K23 A;  2I3R A;  1BZH A;  3ZM1 A;  1G1H A;  1R6H A;  1OET A;  2I4G A;  1NL9 A;  1U26 A;  3O4U A;  2BV5 A;  1Q6J A;  2OUD A;  5LXQ B;  2QBQ A;  1KAK A;  4DGP A;  3S3F A;  3BLT A;  4QAP A;  3LJ8 A;  1J4X A;  5J8R A;  3RZ2 A;  1KAV A;  4GWF A;  2FH7 A;  1P15 A;  4HRF A;  2C46 A;  2I1Y A;  5KA4 A;  4OHD A;  1WCH A;  1XBO A;  1D5R A;  4RI4 A;  3EZZ A;  2IMG A;  1YWF A;  2CJZ A;  2CNE A;  1G4W R;  4WU3 A;  4B04 A;  3MMJ A;  2H4G A;  1G4U S;  2NZ6 A;  2Q05 A;  2P4D A;  3V0G A;  1G7F A;  2NT7 A;  1Q6T A;  2I4E A;  4JMJ A;  3S3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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