5KA1A

Protein tyrosine phosphatase 1b delta helix 7 mutant in complex with tcs401, closed state
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
284
structure length
284
Chain Sequence
ASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 100
structure length 284
sequence length 284
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka1A00
2NZ6A 1YTNA 2Y2FA 4RHGA 3D9CA 3OLRA 2BV5A 4RH5A 4JMJA 1SUGA 1FQ1A 1T49A 4D3RA 1WAXA 1NZ7A 2CFVA 3QCIA 5MMZB 1NL9A 1GWZA 3I36A 2J17A 3N0AA 3ZMQA 1G1GA 3AWGA 4AZ1A 3QCLA 2AHSA 2PBNA 2B3OA 4WTYA 2CNFA 5KA4A 2F70A 5KA0A 3ZM1A 1Q6TA 4OHDA 3EAXA 2F46A 2GWOA 2I6MA 3BM8A 2QDPA 1OEMX 1PA9A 2HCMA 2GJTA 4QAPA 2GP0A 2PT0A 2WGPA 2H4GA 4QAHA 4GE6A 3A5JA 2F71A 2I1YA 2I4EA 1G7GA 5EHPA 2AZRA 1G7FA 1NNYA 3F9BA 2FJMA 5IBSA 1NO6A 2G6ZA 2VEUA 1XBOA 2IMGA 2R0BA 4MBBA 1C87A 2I3UA 3SR9A 4JBCA 2CNHA 2I6JA 2SHPA 2Q05A 4DGPA 4GWFA 5I6VA 5M43A 3RGOA 4H1OA 1PXHA 2HY3A 3EZZA 3MOZA 4ZRTA 4GFUA 3ZMPA 3O5XA 4Z6BA 3F81A 3O4UA 5BZZA 3ZM2A 1ECVA 5LXQB 3QCNA 5IBMA 1PTYA 1EEOA 4GRYA 1XM2A 1OEVA 4HRFA 4RKKA 2CJZA 4NNDA 2C7SA 4WU2A 4TVVA 2CMBA 2HNQA 1PTVA 1GFYA 4D3PA 2YDUA 2ESBA 1J4XA 3QCHA 3QKQA 2I4GA 2I5XA 1U25A 2QBPA 4GFVA 3S3HA 1T48A 1ZCKA 2J16B 3RO1A 1ZCLA 2I6PA 1PTTA 1BZCA 1Q6SA 4GRZA 1U24A 2HNPA 1G1HA 2B07A 1P15A 2I6OA 1YGRA 3D42A 3NMEA 4D3QA 1G4WR 4NWGA 3ZM3A 2CM3A 3CWEA 1QXKA 2M3VA 3QCCA 3BRHA 4H34A 1KAVA 1RPMA 1YPTA 1D5RA 2QEPA 3MOWA 2E0TA 3B7OA 2H02A 3A5KA 3ZV2A 2A3KA 4Y2EA 2I4HA 4OHEA 4JMKA 4R0SA 5J8RA 3V0HA 1XXPA 4GE2A 4KYQA 1OEUA 1KAKA 4GE5A 1NWLA 1YTWA 1PYNA 4PVGA 3D1OA 3BLTA 4OHLA 2C46A 5BZXA 5KABA 2H4VA 3QCKA 4ZI4A 1C84A 5BX1A 1L8GA 2B49A 3O4TA 1FPRA 2VEXA 1LYVA 2H03A 1ONYA 4RH9A 2F6YA 2PQ5A 3O4SA 2Y96A 5AWXA 3I7ZA 4S0GA 3CM3A 4BPCA 2I75A 1Q6PA 2OOQA 2Q47A 1ZZWA 3QCGA 3V0EA 1C83A 5K22A 2VEYA 2I42A 3H2XA 4WU3A 2CM7A 2HXPA 2NT2A 2HVLA 2QCTA 2DXPA 1OEOX 3QCEA 3F9AA 1Q6JA 3S3FA 1T4JA 3QCBA 1A5YA 4JNBA 2HC1A 2QBRA 2NT7A 1V3AA 1YFOA 2P4DA 1LQFA 1JF7A 4ERCA 2ZMMA 2CNGA 5KADA 1XRIA 1NWEA 3RGQA 2F6TA 4RI4A 1G1FA 3MMJA 3ZM0A 2VEWA 3S4EA 3I80A 3S3KA 2BGEA 4HJQA 3U96A 3V0FA 1PA1A 2A8BA 1VHRA 2F6FA 4R0TA 4R30A 2QDCA 4NX8A 3SMEA 5KA3A 4DGXA 1ZC0A 2G59A 5HDEA 5KA7A 2QDMA 4RDDA 1XXVA 3EB1A 1I57A 5K25A 3LJ8A 1X24A 2NTAA 3O3LA 4HJPA 5KA1A 2BGDA 4RI5A 3F41A 1WRMA 5K9WA 3D1HA 4J51A 2MBCA 4KYRA 1LARA 3BLUA 2I6IA 4NYHA 3V0IA 1G4US 4ICZA 3QCMA 2JJDA 2NLKA 1OHEA 2BZLA 1YGUA 2F6WA 2PSZA 1OHCA 3QKPA 1QZ0A 4I8NA 2HB1A 1YTSA 2QBQA 3OMHA 3S3EA 2CM2A 2CNIA 3M4UA 3V0JA 1ONZA 5K23A 1M3GA 2H4KA 2OC3A 2F6VA 1AAXA 4QUNA 2F6ZA 2OZ5A 5EHRA 3EMUA 1YWFA 2FH7A 1Q1MA 1I9TA 2FJNA 5BUGA 1PH0A 3EU0A 4KI9A 1OHDA 2CM8A 4NWFA 1I9SA 4QBEA 4BJOA 3D1QA 2NV5A 2QCJA 2PA5A 2H04A 1YZ4A 2B4OA 2CNEA 1WCHA 3S4OA 2J16A 5KACA 1JLNA 1Q6NA 1BZJA 5KA8A 2ZN7A 1L8KA 1C85A 4OHIA 3GXGA 3GXHA 2CMCA 3QCFA 4IKCA 3F99A 3V0DA 1R6HA 3QCJA 1PTUA 4PYHA 5K24A 3AWFA 2BIJA 5KAAA 2I3RA 1Q6MA 3RZ2A 2QBSA 5KA9A 2CMAA 3V0GA 5GTJA 4QUMA 1EENA 2PI7A 2HC2A 4OHHA 1OETA 2OUDA 3AWEA 4ZN5A 4WOHA 1U26A 2VEVA 1BZHA 4B04A 1YN9A 1C86A 2B4SA 1RXDA 1FPZA 2P6XA 1C88A 5KA2A 3QCDA 2B4UA 2RF6A 4QBWA 4YAAA 1OESA 1MKPA 2B4PA 3PS5A 5K9VA 4YR8B 3D44A 4Y14A 4GS0A
chains in the Genus database with same CATH superfamily
4CVMA 4CVKA 2NZ6A 1YTNA 2Y2FA 3MVNA 4RHGA 3D9CA 3OLRA 2BV5A 4RH5A 3ZM6A 4JMJA 1SUGA 1FQ1A 1T49A 4D3RA 1WAXA 1NZ7A 2CFVA 3QCIA 5MMZB 1NL9A 1GWZA 3I36A 2GC5A 2J17A 3N0AA 3ZMQA 1G1GA 3AWGA 4AZ1A 3QCLA 2AHSA 1GG4A 2PBNA 2B3OA 4WTYA 2CNFA 3QCZA 2F70A 3HN7A 3ZM1A 5KA4A 5KA0A 1Q6TA 4OHDA 3EAXA 2F46A 2GWOA 2I6MA 3BM8A 2QDPA 1OEMX 1PA9A 2HCMA 2GJTA 4QAPA 2GP0A 2PT0A 2WGPA 2H4GA 4QAHA 2AM1A 4GE6A 3A5JA 1JBWA 2F71A 2I1YA 2I4EA 1G7GA 5EHPA 2AZRA 2VORA 1G7FA 2F00A 1P31A 1NNYA 3F9BA 4QF5A 2FJMA 5IBSA 1NO6A 2G6ZA 2VEUA 1XBOA 2IMGA 2R0BA 4MBBA 1C87A 2JFHA 2I3UA 3SR9A 4JBCA 2CNHA 5A5EA 2I6JA 2SHPA 2Q05A 4DGPA 4GWFA 5A5FA 5I6VA 3RGOA 5M43A 4H1OA 1PXHA 2HY3A 3EZZA 3MOZA 4ZRTA 4GFUA 3ZMPA 3O5XA 4Z6BA 3F81A 3O4UA 5BZZA 3ZM2A 1ECVA 5LXQB 3QCNA 5IBMA 1PTYA 1EEOA 4GRYA 1XM2A 1OEVA 4QDIA 4HRFA 4RKKA 3ZM5A 2CJZA 4NNDA 2JFFA 2C7SA 4WU2A 4UAGA 4TVVA 2CMBA 2HNQA 1PTVA 1GFYA 2WJPA 4D3PA 2YDUA 2ESBA 1J4XA 3QCHA 3QKQA 2I4GA 2I5XA 1U25A 2QBPA 4GFVA 3S3HA 1T48A 4HV4A 1ZCKA 2J16B 3RO1A 1ZCLA 2I6PA 1PTTA 1BZCA 1Q6SA 4GRZA 1U24A 2HNPA 1G1HA 2B07A 1P15A 3UAGA 2I6OA 1YGRA 3D42A 3NMEA 4D3QA 1G4WR 4NWGA 3ZM3A 2CM3A 3CWEA 1QXKA 2M3VA 3QCCA 3BRHA 4H34A 1KAVA 1RPMA 1YPTA 1D5RA 2QEPA 3MOWA 1O5ZA 2E0TA 3B7OA 2H02A 3A5KA 3PYZA 3ZV2A 2A3KA 4Y2EA 2I4HA 1GQQA 4JMKA 4OHEA 4R0SA 5J8RA 3V0HA 1XXPA 2Y68A 4GE2A 4KYQA 1OEUA 1KAKA 4GE5A 1NWLA 1YTWA 1PYNA 4PVGA 3D1OA 3BLTA 4OHLA 2C46A 5BZXA 5KABA 2H4VA 3QCKA 1UAGA 2AM2A 4ZI4A 1C84A 5BX1A 2Y66A 1L8GA 2B49A 4ZIYA 3O4TA 1FPRA 2VEXA 1LYVA 2H03A 1ONYA 4RH9A 2F6YA 2PQ5A 3O4SA 2Y96A 5AWXA 3I7ZA 4S0GA 3CM3A 4BPCA 2I75A 1Q6PA 2OOQA 2Q47A 1ZZWA 3QCGA 3V0EA 1C83A 2JFGA 5K22A 2VEYA 2I42A 3H2XA 4WU3A 2CM7A 2X5OA 2HXPA 2NT2A 2HVLA 2QCTA 2DXPA 1OEOX 3QCEA 2UUPA 3F9AA 1Q6JA 3S3FA 1T4JA 3QCBA 4C13A 4BUBA 1A5YA 4JNBA 2HC1A 2QBRA 2NT7A 1V3AA 1YFOA 2P4DA 1LQFA 1JF7A 4ERCA 2ZMMA 2CNGA 5KADA 1XRIA 1NWEA 3RGQA 2F6TA 4RI4A 1G1FA 3MMJA 3ZM0A 2VEWA 1P3DA 3S4EA 3I80A 3S3KA 4BUCA 2BGEA 4HJQA 3U96A 3V0FA 1PA1A 2A8BA 1VHRA 2F6FA 4R0TA 1GQYA 4R30A 2QDCA 2VTEA 4NX8A 3SMEA 5KA3A 4DGXA 1W7KA 1ZC0A 2G59A 5HDEA 5KA7A 2QDMA 4RDDA 1XXVA 3EB1A 1I57A 5K25A 3LJ8A 1X24A 2NTAA 3O3LA 4HJPA 5KA1A 2BGDA 4RI5A 1WRMA 3F41A 5K9WA 3D1HA 2VTDA 4J51A 2MBCA 4KYRA 1LARA 3BLUA 2I6IA 4NYHA 3V0IA 1G4US 2VOSA 4ICZA 3QCMA 2JJDA 2NLKA 1OHEA 2BZLA 1YGUA 2F6WA 2PSZA 1OHCA 3QKPA 1QZ0A 2UAGA 2Y1OA 4I8NA 2HB1A 1YTSA 2QBQA 2GCBA 3OMHA 3S3EA 2CM2A 4CVLA 2CNIA 3M4UA 3V0JA 1ONZA 3NRSA 5K23A 1M3GA 2H4KA 2OC3A 1E0DA 2F6VA 1AAXA 4QUNA 2F6ZA 2OZ5A 5EHRA 3EMUA 1YWFA 2FH7A 1Q1MA 2UUOA 1I9TA 3ZL8A 2FJNA 5BUGA 1PH0A 3EU0A 4KI9A 1OHDA 2CM8A 4NWFA 1I9SA 4QBEA 1W78A 4BJOA 3D1QA 2NV5A 2QCJA 2PA5A 2H04A 1YZ4A 2B4OA 1FGSA 1EEHA 2CNEA 1WCHA 3S4OA 2XPCA 2J16A 5KACA 1JLNA 1Q6NA 1BZJA 2Y67A 5KA8A 2ZN7A 1L8KA 1C85A 4OHIA 1E8CA 3GXGA 3GXHA 2CMCA 3QCFA 4IKCA 3F99A 3V0DA 1R6HA 3QCJA 2XJAA 1PTUA 4PYHA 5K24A 3AWFA 2BIJA 5KAAA 2I3RA 1Q6MA 3RZ2A 4C12A 2QBSA 5KA9A 2CMAA 3V0GA 5GTJA 4QUMA 1EENA 2PI7A 2HC2A 4OHHA 1OETA 2OUDA 3AWEA 4ZN5A 4WOHA 1U26A 2VEVA 1BZHA 2WTZA 4B04A 1YN9A 3N2AA 1C86A 2B4SA 1RXDA 2GC6A 1FPZA 2P6XA 1C88A 5KA2A 2GCAA 2B4UA 2RF6A 3QCDA 4QBWA 4YAAA 1OESA 1J6UA 1MKPA 2B4PA 3PS5A 5K9VA 1JBVA 4YR8B 3D44A 4Y14A 3LK7A 4GS0A
chains in the Genus database with same CATH topology
2NZ6A 1YTNA 2Y2FA 4RHGA 3D9CA 3OLRA 2BV5A 4RH5A 4JMJA 1SUGA 1FQ1A 1T49A 4D3RA 1WAXA 1NZ7A 2CFVA 3QCIA 5MMZB 1NL9A 1GWZA 3I36A 2J17A 3N0AA 3ZMQA 1G1GA 3AWGA 4AZ1A 3QCLA 2AHSA 2PBNA 2B3OA 4WTYA 2CNFA 5KA4A 2F70A 5KA0A 3ZM1A 1Q6TA 4OHDA 3EAXA 2F46A 2GWOA 2I6MA 3BM8A 2QDPA 1OEMX 1PA9A 2HCMA 2GJTA 4QAPA 2GP0A 2PT0A 2WGPA 2H4GA 4QAHA 4GE6A 3A5JA 2F71A 2I1YA 2I4EA 1G7GA 5EHPA 2AZRA 1G7FA 1NNYA 3F9BA 2FJMA 5IBSA 1NO6A 2G6ZA 2VEUA 1XBOA 2IMGA 2R0BA 4MBBA 1C87A 2I3UA 3SR9A 4JBCA 2CNHA 2I6JA 2SHPA 2Q05A 4DGPA 4GWFA 5I6VA 5M43A 3RGOA 4H1OA 1PXHA 2HY3A 3EZZA 3MOZA 4ZRTA 4GFUA 3ZMPA 3O5XA 4Z6BA 3F81A 3O4UA 5BZZA 3ZM2A 1ECVA 5LXQB 3QCNA 5IBMA 1PTYA 1EEOA 4GRYA 1XM2A 1OEVA 4HRFA 4RKKA 2CJZA 4NNDA 2C7SA 4WU2A 4TVVA 2CMBA 2HNQA 1PTVA 1GFYA 4D3PA 2YDUA 2ESBA 1J4XA 3QCHA 3QKQA 2I4GA 2I5XA 1U25A 2QBPA 4GFVA 3S3HA 1T48A 1ZCKA 2J16B 3RO1A 1ZCLA 2I6PA 1PTTA 1BZCA 1Q6SA 4GRZA 1U24A 2HNPA 1G1HA 2B07A 1P15A 2I6OA 1YGRA 3D42A 3NMEA 4D3QA 1G4WR 4NWGA 3ZM3A 2CM3A 3CWEA 1QXKA 2M3VA 3QCCA 3BRHA 4H34A 1KAVA 1RPMA 1YPTA 1D5RA 2QEPA 3MOWA 2E0TA 3B7OA 2H02A 3A5KA 3ZV2A 2A3KA 4Y2EA 2I4HA 4OHEA 4JMKA 4R0SA 5J8RA 3V0HA 1XXPA 4GE2A 4KYQA 1OEUA 1KAKA 4GE5A 1NWLA 1YTWA 1PYNA 4PVGA 3D1OA 3BLTA 4OHLA 2C46A 5BZXA 5KABA 2H4VA 3QCKA 4ZI4A 1C84A 5BX1A 1L8GA 2B49A 3O4TA 1FPRA 2VEXA 1LYVA 2H03A 1ONYA 4RH9A 2F6YA 2PQ5A 3O4SA 2Y96A 5AWXA 3I7ZA 4S0GA 3CM3A 4BPCA 2I75A 1Q6PA 2OOQA 2Q47A 1ZZWA 3QCGA 3V0EA 1C83A 5K22A 2VEYA 2I42A 3H2XA 4WU3A 2CM7A 2HXPA 2NT2A 2HVLA 2QCTA 2DXPA 1OEOX 3QCEA 3F9AA 1Q6JA 3S3FA 1T4JA 3QCBA 1A5YA 4JNBA 2HC1A 2QBRA 2NT7A 1V3AA 1YFOA 2P4DA 1LQFA 1JF7A 4ERCA 2ZMMA 2CNGA 5KADA 1XRIA 1NWEA 3RGQA 2F6TA 4RI4A 1G1FA 3MMJA 3ZM0A 2VEWA 3S4EA 3I80A 3S3KA 2BGEA 4HJQA 3U96A 3V0FA 1PA1A 2A8BA 1VHRA 2F6FA 4R0TA 4R30A 2QDCA 4NX8A 3SMEA 5KA3A 4DGXA 1ZC0A 2G59A 5HDEA 5KA7A 2QDMA 4RDDA 1XXVA 3EB1A 1I57A 5K25A 3LJ8A 1X24A 2NTAA 3O3LA 4HJPA 5KA1A 2BGDA 4RI5A 3F41A 1WRMA 5K9WA 3D1HA 4J51A 2MBCA 4KYRA 1LARA 3BLUA 2I6IA 4NYHA 3V0IA 1G4US 4ICZA 3QCMA 2JJDA 2NLKA 1OHEA 2BZLA 1YGUA 2F6WA 2PSZA 1OHCA 3QKPA 1QZ0A 4I8NA 2HB1A 1YTSA 2QBQA 3OMHA 3S3EA 2CM2A 2CNIA 3M4UA 3V0JA 1ONZA 5K23A 1M3GA 2H4KA 2OC3A 2F6VA 1AAXA 4QUNA 2F6ZA 2OZ5A 5EHRA 3EMUA 1YWFA 2FH7A 1Q1MA 1I9TA 2FJNA 5BUGA 1PH0A 3EU0A 4KI9A 1OHDA 2CM8A 4NWFA 1I9SA 4QBEA 4BJOA 3D1QA 2NV5A 2QCJA 2PA5A 2H04A 1YZ4A 2B4OA 2CNEA 1WCHA 3S4OA 2J16A 5KACA 1JLNA 1Q6NA 1BZJA 5KA8A 2ZN7A 1L8KA 1C85A 4OHIA 3GXGA 3GXHA 2CMCA 3QCFA 4IKCA 3F99A 3V0DA 1R6HA 3QCJA 1PTUA 4PYHA 5K24A 3AWFA 2BIJA 5KAAA 2I3RA 1Q6MA 3RZ2A 2QBSA 5KA9A 2CMAA 3V0GA 5GTJA 4QUMA 1EENA 2PI7A 2HC2A 4OHHA 1OETA 2OUDA 3AWEA 4ZN5A 4WOHA 1U26A 2VEVA 1BZHA 4B04A 1YN9A 1C86A 2B4SA 1RXDA 1FPZA 2P6XA 1C88A 5KA2A 3QCDA 2B4UA 2RF6A 4QBWA 4YAAA 1OESA 1MKPA 2B4PA 3PS5A 5K9VA 4YR8B 3D44A 4Y14A 4GS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NZ6 A;  1YTN A;  2Y2F A;  4RHG A;  3D9C A;  3OLR A;  2BV5 A;  4RH5 A;  4JMJ A;  1SUG A;  1FQ1 A;  1T49 A;  4D3R A;  1WAX A;  1NZ7 A;  2CFV A;  3QCI A;  5MMZ B;  1NL9 A;  1GWZ A;  3I36 A;  2J17 A;  3N0A A;  3ZMQ A;  1G1G A;  3AWG A;  4AZ1 A;  3QCL A;  2AHS A;  2PBN A;  2B3O A;  4WTY A;  2CNF A;  5KA4 A;  2F70 A;  5KA0 A;  3ZM1 A;  1Q6T A;  4OHD A;  3EAX A;  2F46 A;  2GWO A;  2I6M A;  3BM8 A;  2QDP A;  1OEM X;  1PA9 A;  2HCM A;  2GJT A;  4QAP A;  2GP0 A;  2PT0 A;  2WGP A;  2H4G A;  4QAH A;  4GE6 A;  3A5J A;  2F71 A;  2I1Y A;  2I4E A;  1G7G A;  5EHP A;  2AZR A;  1G7F A;  1NNY A;  3F9B A;  2FJM A;  5IBS A;  1NO6 A;  2G6Z A;  2VEU A;  1XBO A;  2IMG A;  2R0B A;  4MBB A;  1C87 A;  2I3U A;  3SR9 A;  4JBC A;  2CNH A;  2I6J A;  2SHP A;  2Q05 A;  4DGP A;  4GWF A;  5I6V A;  5M43 A;  3RGO A;  4H1O A;  1PXH A;  2HY3 A;  3EZZ A;  3MOZ A;  4ZRT A;  4GFU A;  3ZMP A;  3O5X A;  4Z6B A;  3F81 A;  3O4U A;  5BZZ A;  3ZM2 A;  1ECV A;  5LXQ B;  3QCN A;  5IBM A;  1PTY A;  1EEO A;  4GRY A;  1XM2 A;  1OEV A;  4HRF A;  4RKK A;  2CJZ A;  4NND A;  2C7S A;  4WU2 A;  4TVV A;  2CMB A;  2HNQ A;  1PTV A;  1GFY A;  4D3P A;  2YDU A;  2ESB A;  1J4X A;  3QCH A;  3QKQ A;  2I4G A;  2I5X A;  1U25 A;  2QBP A;  4GFV A;  3S3H A;  1T48 A;  1ZCK A;  2J16 B;  3RO1 A;  1ZCL A;  2I6P A;  1PTT A;  1BZC A;  1Q6S A;  4GRZ A;  1U24 A;  2HNP A;  1G1H A;  2B07 A;  1P15 A;  2I6O A;  1YGR A;  3D42 A;  3NME A;  4D3Q A;  1G4W R;  4NWG A;  3ZM3 A;  2CM3 A;  3CWE A;  1QXK A;  2M3V A;  3QCC A;  3BRH A;  4H34 A;  1KAV A;  1RPM A;  1YPT A;  1D5R A;  2QEP A;  3MOW A;  2E0T A;  3B7O A;  2H02 A;  3A5K A;  3ZV2 A;  2A3K A;  4Y2E A;  2I4H A;  4OHE A;  4JMK A;  4R0S A;  5J8R A;  3V0H A;  1XXP A;  4GE2 A;  4KYQ A;  1OEU A;  1KAK A;  4GE5 A;  1NWL A;  1YTW A;  1PYN A;  4PVG A;  3D1O A;  3BLT A;  4OHL A;  2C46 A;  5BZX A;  5KAB A;  2H4V A;  3QCK A;  4ZI4 A;  1C84 A;  5BX1 A;  1L8G A;  2B49 A;  3O4T A;  1FPR A;  2VEX A;  1LYV A;  2H03 A;  1ONY A;  4RH9 A;  2F6Y A;  2PQ5 A;  3O4S A;  2Y96 A;  5AWX A;  3I7Z A;  4S0G A;  3CM3 A;  4BPC A;  2I75 A;  1Q6P A;  2OOQ A;  2Q47 A;  1ZZW A;  3QCG A;  3V0E A;  1C83 A;  5K22 A;  2VEY A;  2I42 A;  3H2X A;  4WU3 A;  2CM7 A;  2HXP A;  2NT2 A;  2HVL A;  2QCT A;  2DXP A;  1OEO X;  3QCE A;  3F9A A;  1Q6J A;  3S3F A;  1T4J A;  3QCB A;  1A5Y A;  4JNB A;  2HC1 A;  2QBR A;  2NT7 A;  1V3A A;  1YFO A;  2P4D A;  1LQF A;  1JF7 A;  4ERC A;  2ZMM A;  2CNG A;  5KAD A;  1XRI A;  1NWE A;  3RGQ A;  2F6T A;  4RI4 A;  1G1F A;  3MMJ A;  3ZM0 A;  2VEW A;  3S4E A;  3I80 A;  3S3K A;  2BGE A;  4HJQ A;  3U96 A;  3V0F A;  1PA1 A;  2A8B A;  1VHR A;  2F6F A;  4R0T A;  4R30 A;  2QDC A;  4NX8 A;  3SME A;  5KA3 A;  4DGX A;  1ZC0 A;  2G59 A;  5HDE A;  5KA7 A;  2QDM A;  4RDD A;  1XXV A;  3EB1 A;  1I57 A;  5K25 A;  3LJ8 A;  1X24 A;  2NTA A;  3O3L A;  4HJP A;  5KA1 A;  2BGD A;  4RI5 A;  3F41 A;  1WRM A;  5K9W A;  3D1H A;  4J51 A;  2MBC A;  4KYR A;  1LAR A;  3BLU A;  2I6I A;  4NYH A;  3V0I A;  1G4U S;  4ICZ A;  3QCM A;  2JJD A;  2NLK A;  1OHE A;  2BZL A;  1YGU A;  2F6W A;  2PSZ A;  1OHC A;  3QKP A;  1QZ0 A;  4I8N A;  2HB1 A;  1YTS A;  2QBQ A;  3OMH A;  3S3E A;  2CM2 A;  2CNI A;  3M4U A;  3V0J A;  1ONZ A;  5K23 A;  1M3G A;  2H4K A;  2OC3 A;  2F6V A;  1AAX A;  4QUN A;  2F6Z A;  2OZ5 A;  5EHR A;  3EMU A;  1YWF A;  2FH7 A;  1Q1M A;  1I9T A;  2FJN A;  5BUG A;  1PH0 A;  3EU0 A;  4KI9 A;  1OHD A;  2CM8 A;  4NWF A;  1I9S A;  4QBE A;  4BJO A;  3D1Q A;  2NV5 A;  2QCJ A;  2PA5 A;  2H04 A;  1YZ4 A;  2B4O A;  2CNE A;  1WCH A;  3S4O A;  2J16 A;  5KAC A;  1JLN A;  1Q6N A;  1BZJ A;  5KA8 A;  2ZN7 A;  1L8K A;  1C85 A;  4OHI A;  3GXG A;  3GXH A;  2CMC A;  3QCF A;  4IKC A;  3F99 A;  3V0D A;  1R6H A;  3QCJ A;  1PTU A;  4PYH A;  5K24 A;  3AWF A;  2BIJ A;  5KAA A;  2I3R A;  1Q6M A;  3RZ2 A;  2QBS A;  5KA9 A;  2CMA A;  3V0G A;  5GTJ A;  4QUM A;  1EEN A;  2PI7 A;  2HC2 A;  4OHH A;  1OET A;  2OUD A;  3AWE A;  4ZN5 A;  4WOH A;  1U26 A;  2VEV A;  1BZH A;  4B04 A;  1YN9 A;  1C86 A;  2B4S A;  1RXD A;  1FPZ A;  2P6X A;  1C88 A;  5KA2 A;  3QCD A;  2B4U A;  2RF6 A;  4QBW A;  4YAA A;  1OES A;  1MKP A;  2B4P A;  3PS5 A;  5K9V A;  4YR8 B;  3D44 A;  4Y14 A;  4GS0 A; 
#chains in the Genus database with same CATH topology
 4CVM A;  4CVK A;  2NZ6 A;  1YTN A;  2Y2F A;  3MVN A;  4RHG A;  3D9C A;  3OLR A;  2BV5 A;  4RH5 A;  3ZM6 A;  4JMJ A;  1SUG A;  1FQ1 A;  1T49 A;  4D3R A;  1WAX A;  1NZ7 A;  2CFV A;  3QCI A;  5MMZ B;  1NL9 A;  1GWZ A;  3I36 A;  2GC5 A;  2J17 A;  3N0A A;  3ZMQ A;  1G1G A;  3AWG A;  4AZ1 A;  3QCL A;  2AHS A;  1GG4 A;  2PBN A;  2B3O A;  4WTY A;  2CNF A;  3QCZ A;  2F70 A;  3HN7 A;  3ZM1 A;  5KA4 A;  5KA0 A;  1Q6T A;  4OHD A;  3EAX A;  2F46 A;  2GWO A;  2I6M A;  3BM8 A;  2QDP A;  1OEM X;  1PA9 A;  2HCM A;  2GJT A;  4QAP A;  2GP0 A;  2PT0 A;  2WGP A;  2H4G A;  4QAH A;  2AM1 A;  4GE6 A;  3A5J A;  1JBW A;  2F71 A;  2I1Y A;  2I4E A;  1G7G A;  5EHP A;  2AZR A;  2VOR A;  1G7F A;  2F00 A;  1P31 A;  1NNY A;  3F9B A;  4QF5 A;  2FJM A;  5IBS A;  1NO6 A;  2G6Z A;  2VEU A;  1XBO A;  2IMG A;  2R0B A;  4MBB A;  1C87 A;  2JFH A;  2I3U A;  3SR9 A;  4JBC A;  2CNH A;  5A5E A;  2I6J A;  2SHP A;  2Q05 A;  4DGP A;  4GWF A;  5A5F A;  5I6V A;  3RGO A;  5M43 A;  4H1O A;  1PXH A;  2HY3 A;  3EZZ A;  3MOZ A;  4ZRT A;  4GFU A;  3ZMP A;  3O5X A;  4Z6B A;  3F81 A;  3O4U A;  5BZZ A;  3ZM2 A;  1ECV A;  5LXQ B;  3QCN A;  5IBM A;  1PTY A;  1EEO A;  4GRY A;  1XM2 A;  1OEV A;  4QDI A;  4HRF A;  4RKK A;  3ZM5 A;  2CJZ A;  4NND A;  2JFF A;  2C7S A;  4WU2 A;  4UAG A;  4TVV A;  2CMB A;  2HNQ A;  1PTV A;  1GFY A;  2WJP A;  4D3P A;  2YDU A;  2ESB A;  1J4X A;  3QCH A;  3QKQ A;  2I4G A;  2I5X A;  1U25 A;  2QBP A;  4GFV A;  3S3H A;  1T48 A;  4HV4 A;  1ZCK A;  2J16 B;  3RO1 A;  1ZCL A;  2I6P A;  1PTT A;  1BZC A;  1Q6S A;  4GRZ A;  1U24 A;  2HNP A;  1G1H A;  2B07 A;  1P15 A;  3UAG A;  2I6O A;  1YGR A;  3D42 A;  3NME A;  4D3Q A;  1G4W R;  4NWG A;  3ZM3 A;  2CM3 A;  3CWE A;  1QXK A;  2M3V A;  3QCC A;  3BRH A;  4H34 A;  1KAV A;  1RPM A;  1YPT A;  1D5R A;  2QEP A;  3MOW A;  1O5Z A;  2E0T A;  3B7O A;  2H02 A;  3A5K A;  3PYZ A;  3ZV2 A;  2A3K A;  4Y2E A;  2I4H A;  1GQQ A;  4JMK A;  4OHE A;  4R0S A;  5J8R A;  3V0H A;  1XXP A;  2Y68 A;  4GE2 A;  4KYQ A;  1OEU A;  1KAK A;  4GE5 A;  1NWL A;  1YTW A;  1PYN A;  4PVG A;  3D1O A;  3BLT A;  4OHL A;  2C46 A;  5BZX A;  5KAB A;  2H4V A;  3QCK A;  1UAG A;  2AM2 A;  4ZI4 A;  1C84 A;  5BX1 A;  2Y66 A;  1L8G A;  2B49 A;  4ZIY A;  3O4T A;  1FPR A;  2VEX A;  1LYV A;  2H03 A;  1ONY A;  4RH9 A;  2F6Y A;  2PQ5 A;  3O4S A;  2Y96 A;  5AWX A;  3I7Z A;  4S0G A;  3CM3 A;  4BPC A;  2I75 A;  1Q6P A;  2OOQ A;  2Q47 A;  1ZZW A;  3QCG A;  3V0E A;  1C83 A;  2JFG A;  5K22 A;  2VEY A;  2I42 A;  3H2X A;  4WU3 A;  2CM7 A;  2X5O A;  2HXP A;  2NT2 A;  2HVL A;  2QCT A;  2DXP A;  1OEO X;  3QCE A;  2UUP A;  3F9A A;  1Q6J A;  3S3F A;  1T4J A;  3QCB A;  4C13 A;  4BUB A;  1A5Y A;  4JNB A;  2HC1 A;  2QBR A;  2NT7 A;  1V3A A;  1YFO A;  2P4D A;  1LQF A;  1JF7 A;  4ERC A;  2ZMM A;  2CNG A;  5KAD A;  1XRI A;  1NWE A;  3RGQ A;  2F6T A;  4RI4 A;  1G1F A;  3MMJ A;  3ZM0 A;  2VEW A;  1P3D A;  3S4E A;  3I80 A;  3S3K A;  4BUC A;  2BGE A;  4HJQ A;  3U96 A;  3V0F A;  1PA1 A;  2A8B A;  1VHR A;  2F6F A;  4R0T A;  1GQY A;  4R30 A;  2QDC A;  2VTE A;  4NX8 A;  3SME A;  5KA3 A;  4DGX A;  1W7K A;  1ZC0 A;  2G59 A;  5HDE A;  5KA7 A;  2QDM A;  4RDD A;  1XXV A;  3EB1 A;  1I57 A;  5K25 A;  3LJ8 A;  1X24 A;  2NTA A;  3O3L A;  4HJP A;  5KA1 A;  2BGD A;  4RI5 A;  1WRM A;  3F41 A;  5K9W A;  3D1H A;  2VTD A;  4J51 A;  2MBC A;  4KYR A;  1LAR A;  3BLU A;  2I6I A;  4NYH A;  3V0I A;  1G4U S;  2VOS A;  4ICZ A;  3QCM A;  2JJD A;  2NLK A;  1OHE A;  2BZL A;  1YGU A;  2F6W A;  2PSZ A;  1OHC A;  3QKP A;  1QZ0 A;  2UAG A;  2Y1O A;  4I8N A;  2HB1 A;  1YTS A;  2QBQ A;  2GCB A;  3OMH A;  3S3E A;  2CM2 A;  4CVL A;  2CNI A;  3M4U A;  3V0J A;  1ONZ A;  3NRS A;  5K23 A;  1M3G A;  2H4K A;  2OC3 A;  1E0D A;  2F6V A;  1AAX A;  4QUN A;  2F6Z A;  2OZ5 A;  5EHR A;  3EMU A;  1YWF A;  2FH7 A;  1Q1M A;  2UUO A;  1I9T A;  3ZL8 A;  2FJN A;  5BUG A;  1PH0 A;  3EU0 A;  4KI9 A;  1OHD A;  2CM8 A;  4NWF A;  1I9S A;  4QBE A;  1W78 A;  4BJO A;  3D1Q A;  2NV5 A;  2QCJ A;  2PA5 A;  2H04 A;  1YZ4 A;  2B4O A;  1FGS A;  1EEH A;  2CNE A;  1WCH A;  3S4O A;  2XPC A;  2J16 A;  5KAC A;  1JLN A;  1Q6N A;  1BZJ A;  2Y67 A;  5KA8 A;  2ZN7 A;  1L8K A;  1C85 A;  4OHI A;  1E8C A;  3GXG A;  3GXH A;  2CMC A;  3QCF A;  4IKC A;  3F99 A;  3V0D A;  1R6H A;  3QCJ A;  2XJA A;  1PTU A;  4PYH A;  5K24 A;  3AWF A;  2BIJ A;  5KAA A;  2I3R A;  1Q6M A;  3RZ2 A;  4C12 A;  2QBS A;  5KA9 A;  2CMA A;  3V0G A;  5GTJ A;  4QUM A;  1EEN A;  2PI7 A;  2HC2 A;  4OHH A;  1OET A;  2OUD A;  3AWE A;  4ZN5 A;  4WOH A;  1U26 A;  2VEV A;  1BZH A;  2WTZ A;  4B04 A;  1YN9 A;  3N2A A;  1C86 A;  2B4S A;  1RXD A;  2GC6 A;  1FPZ A;  2P6X A;  1C88 A;  5KA2 A;  2GCA A;  2B4U A;  2RF6 A;  3QCD A;  4QBW A;  4YAA A;  1OES A;  1J6U A;  1MKP A;  2B4P A;  3PS5 A;  5K9V A;  1JBV A;  4YR8 B;  3D44 A;  4Y14 A;  3LK7 A;  4GS0 A; 
#chains in the Genus database with same CATH homology
 2NZ6 A;  1YTN A;  2Y2F A;  4RHG A;  3D9C A;  3OLR A;  2BV5 A;  4RH5 A;  4JMJ A;  1SUG A;  1FQ1 A;  1T49 A;  4D3R A;  1WAX A;  1NZ7 A;  2CFV A;  3QCI A;  5MMZ B;  1NL9 A;  1GWZ A;  3I36 A;  2J17 A;  3N0A A;  3ZMQ A;  1G1G A;  3AWG A;  4AZ1 A;  3QCL A;  2AHS A;  2PBN A;  2B3O A;  4WTY A;  2CNF A;  5KA4 A;  2F70 A;  5KA0 A;  3ZM1 A;  1Q6T A;  4OHD A;  3EAX A;  2F46 A;  2GWO A;  2I6M A;  3BM8 A;  2QDP A;  1OEM X;  1PA9 A;  2HCM A;  2GJT A;  4QAP A;  2GP0 A;  2PT0 A;  2WGP A;  2H4G A;  4QAH A;  4GE6 A;  3A5J A;  2F71 A;  2I1Y A;  2I4E A;  1G7G A;  5EHP A;  2AZR A;  1G7F A;  1NNY A;  3F9B A;  2FJM A;  5IBS A;  1NO6 A;  2G6Z A;  2VEU A;  1XBO A;  2IMG A;  2R0B A;  4MBB A;  1C87 A;  2I3U A;  3SR9 A;  4JBC A;  2CNH A;  2I6J A;  2SHP A;  2Q05 A;  4DGP A;  4GWF A;  5I6V A;  5M43 A;  3RGO A;  4H1O A;  1PXH A;  2HY3 A;  3EZZ A;  3MOZ A;  4ZRT A;  4GFU A;  3ZMP A;  3O5X A;  4Z6B A;  3F81 A;  3O4U A;  5BZZ A;  3ZM2 A;  1ECV A;  5LXQ B;  3QCN A;  5IBM A;  1PTY A;  1EEO A;  4GRY A;  1XM2 A;  1OEV A;  4HRF A;  4RKK A;  2CJZ A;  4NND A;  2C7S A;  4WU2 A;  4TVV A;  2CMB A;  2HNQ A;  1PTV A;  1GFY A;  4D3P A;  2YDU A;  2ESB A;  1J4X A;  3QCH A;  3QKQ A;  2I4G A;  2I5X A;  1U25 A;  2QBP A;  4GFV A;  3S3H A;  1T48 A;  1ZCK A;  2J16 B;  3RO1 A;  1ZCL A;  2I6P A;  1PTT A;  1BZC A;  1Q6S A;  4GRZ A;  1U24 A;  2HNP A;  1G1H A;  2B07 A;  1P15 A;  2I6O A;  1YGR A;  3D42 A;  3NME A;  4D3Q A;  1G4W R;  4NWG A;  3ZM3 A;  2CM3 A;  3CWE A;  1QXK A;  2M3V A;  3QCC A;  3BRH A;  4H34 A;  1KAV A;  1RPM A;  1YPT A;  1D5R A;  2QEP A;  3MOW A;  2E0T A;  3B7O A;  2H02 A;  3A5K A;  3ZV2 A;  2A3K A;  4Y2E A;  2I4H A;  4OHE A;  4JMK A;  4R0S A;  5J8R A;  3V0H A;  1XXP A;  4GE2 A;  4KYQ A;  1OEU A;  1KAK A;  4GE5 A;  1NWL A;  1YTW A;  1PYN A;  4PVG A;  3D1O A;  3BLT A;  4OHL A;  2C46 A;  5BZX A;  5KAB A;  2H4V A;  3QCK A;  4ZI4 A;  1C84 A;  5BX1 A;  1L8G A;  2B49 A;  3O4T A;  1FPR A;  2VEX A;  1LYV A;  2H03 A;  1ONY A;  4RH9 A;  2F6Y A;  2PQ5 A;  3O4S A;  2Y96 A;  5AWX A;  3I7Z A;  4S0G A;  3CM3 A;  4BPC A;  2I75 A;  1Q6P A;  2OOQ A;  2Q47 A;  1ZZW A;  3QCG A;  3V0E A;  1C83 A;  5K22 A;  2VEY A;  2I42 A;  3H2X A;  4WU3 A;  2CM7 A;  2HXP A;  2NT2 A;  2HVL A;  2QCT A;  2DXP A;  1OEO X;  3QCE A;  3F9A A;  1Q6J A;  3S3F A;  1T4J A;  3QCB A;  1A5Y A;  4JNB A;  2HC1 A;  2QBR A;  2NT7 A;  1V3A A;  1YFO A;  2P4D A;  1LQF A;  1JF7 A;  4ERC A;  2ZMM A;  2CNG A;  5KAD A;  1XRI A;  1NWE A;  3RGQ A;  2F6T A;  4RI4 A;  1G1F A;  3MMJ A;  3ZM0 A;  2VEW A;  3S4E A;  3I80 A;  3S3K A;  2BGE A;  4HJQ A;  3U96 A;  3V0F A;  1PA1 A;  2A8B A;  1VHR A;  2F6F A;  4R0T A;  4R30 A;  2QDC A;  4NX8 A;  3SME A;  5KA3 A;  4DGX A;  1ZC0 A;  2G59 A;  5HDE A;  5KA7 A;  2QDM A;  4RDD A;  1XXV A;  3EB1 A;  1I57 A;  5K25 A;  3LJ8 A;  1X24 A;  2NTA A;  3O3L A;  4HJP A;  5KA1 A;  2BGD A;  4RI5 A;  3F41 A;  1WRM A;  5K9W A;  3D1H A;  4J51 A;  2MBC A;  4KYR A;  1LAR A;  3BLU A;  2I6I A;  4NYH A;  3V0I A;  1G4U S;  4ICZ A;  3QCM A;  2JJD A;  2NLK A;  1OHE A;  2BZL A;  1YGU A;  2F6W A;  2PSZ A;  1OHC A;  3QKP A;  1QZ0 A;  4I8N A;  2HB1 A;  1YTS A;  2QBQ A;  3OMH A;  3S3E A;  2CM2 A;  2CNI A;  3M4U A;  3V0J A;  1ONZ A;  5K23 A;  1M3G A;  2H4K A;  2OC3 A;  2F6V A;  1AAX A;  4QUN A;  2F6Z A;  2OZ5 A;  5EHR A;  3EMU A;  1YWF A;  2FH7 A;  1Q1M A;  1I9T A;  2FJN A;  5BUG A;  1PH0 A;  3EU0 A;  4KI9 A;  1OHD A;  2CM8 A;  4NWF A;  1I9S A;  4QBE A;  4BJO A;  3D1Q A;  2NV5 A;  2QCJ A;  2PA5 A;  2H04 A;  1YZ4 A;  2B4O A;  2CNE A;  1WCH A;  3S4O A;  2J16 A;  5KAC A;  1JLN A;  1Q6N A;  1BZJ A;  5KA8 A;  2ZN7 A;  1L8K A;  1C85 A;  4OHI A;  3GXG A;  3GXH A;  2CMC A;  3QCF A;  4IKC A;  3F99 A;  3V0D A;  1R6H A;  3QCJ A;  1PTU A;  4PYH A;  5K24 A;  3AWF A;  2BIJ A;  5KAA A;  2I3R A;  1Q6M A;  3RZ2 A;  2QBS A;  5KA9 A;  2CMA A;  3V0G A;  5GTJ A;  4QUM A;  1EEN A;  2PI7 A;  2HC2 A;  4OHH A;  1OET A;  2OUD A;  3AWE A;  4ZN5 A;  4WOH A;  1U26 A;  2VEV A;  1BZH A;  4B04 A;  1YN9 A;  1C86 A;  2B4S A;  1RXD A;  1FPZ A;  2P6X A;  1C88 A;  5KA2 A;  3QCD A;  2B4U A;  2RF6 A;  4QBW A;  4YAA A;  1OES A;  1MKP A;  2B4P A;  3PS5 A;  5K9V A;  4YR8 B;  3D44 A;  4Y14 A;  4GS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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