5J8RA

Crystal structure of the catalytic domain of human protein tyrosine phosphatase non-receptor type 12 - k61r mutant
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
298
structure length
296
Chain Sequence
EQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKRNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure and substrate specificity of PTPN12.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 12
total genus 101
structure length 296
sequence length 298
chains with identical sequence B, C, D
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-04-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5j8rA00
3AWGA 1LQFA 2CNGA 2C7SA 4H34A 3QCMA 2F6VA 2QBPA 5J8RA 3RZ2A 1G1FA 1OHEA 4QBEA 2B3OA 1T49A 3F99A 5BZZA 1FPZA 3I80A 4RH9A 3A5KA 4WU3A 1XXVA 1YZ4A 1ONYA 3RGOA 3LJ8A 2CM3A 1QZ0A 3BLTA 5KA7A 5K24A 3MOZA 3V0EA 3SMEA 3GXGA 4RI4A 4OHLA 4GE2A 2FJNA 2CM8A 4ZI4A 4Z6BA 3CM3A 3NMEA 2H03A 3QCFA 2AHSA 1NWLA 2OZ5A 3D42A 4GE6A 5KABA 2HNPA 1WRMA 5EHPA 1OHDA 3D1OA 1KAVA 2NT7A 3BRHA 4J51A 3QCIA 2I42A 2SHPA 3QCLA 1YFOA 2BGDA 1WCHA 1YGUA 4GRYA 3V0JA 2Y2FA 2HXPA 4WOHA 2FH7A 4DGPA 4D3PA 2PBNA 1G7GA 1XM2A 2M3VA 3EZZA 4GE5A 4R0SA 3MOWA 3QCNA 1Q6JA 3U96A 1YTNA 1BZJA 2I4HA 5KA3A 2BIJA 4JNBA 4OHEA 2PT0A 5IBSA 1OHCA 4MBBA 5K22A 2I6JA 2DXPA 3D1QA 1C88A 2CMBA 2NLKA 2OOQA 1G4US 4B04A 3D9CA 2PSZA 4HJPA 2CFVA 2I6PA 1G1GA 2QBQA 5KAAA 2A8BA 3ZM2A 2H02A 1PH0A 3QKPA 4NWGA 2FJMA 5K25A 4GWFA 4HRFA 2F70A 1FQ1A 4GFVA 1RPMA 2J16A 2QCJA 1NL9A 4OHHA 2NTAA 3F9AA 5KA1A 5M43A 4DGXA 1PA1A 1PTUA 4RHGA 1FPRA 1I9SA 2ZN7A 5KADA 1V3AA 2HB1A 2VEVA 2VEXA 5KA4A 1PTVA 1U24A 3EAXA 2A3KA 1RXDA 3H2XA 2BZLA 1AAXA 1NNYA 4NX8A 1LARA 2GP0A 2CJZA 2CMCA 1WAXA 3EMUA 2HY3A 4PVGA 4RKKA 3RO1A 1C84A 1J4XA 1YGRA 3O4UA 1YPTA 3OMHA 3O4SA 2BGEA 3QKQA 2H04A 5K9VA 2CNIA 3F81A 2QDPA 3O4TA 3SR9A 3S3EA 4RDDA 1G1HA 2F6TA 2GJTA 3QCCA 2NZ6A 4S0GA 4H1OA 3V0GA 2F6YA 2B07A 2I75A 3MMJA 1YTSA 1BZHA 2H4VA 5K9WA 1MKPA 2I6MA 2QCTA 2QDMA 1OEUA 1XXPA 1Q6TA 2J16B 3I7ZA 1Q6MA 2QBSA 1Q6SA 2MBCA 2G6ZA 3O3LA 3QCJA 2NV5A 4D3RA 3EB1A 1QXKA 3BM8A 3BLUA 3QCEA 3EU0A 4YR8B 1X24A 1C86A 3QCDA 2I3UA 1U25A 1C87A 2PI7A 4JBCA 2HC1A 2CNHA 5I6VA 4AZ1A 2ESBA 4QAPA 2B49A 4WU2A 3QCBA 4ZN5A 1EENA 2F6FA 2I1YA 4R0TA 2I6IA 4IKCA 1LYVA 2CNEA 5KA9A 3N0AA 3V0HA 4QBWA 4NWFA 2VEWA 4WTYA 2F6ZA 1ONZA 3ZMPA 2HCMA 2I4EA 4QUMA 2CM2A 1XBOA 3D44A 1OEMX 2IMGA 2QEPA 4KI9A 2PA5A 3B7OA 1EEOA 2B4PA 2YDUA 1BZCA 1ZC0A 4YAAA 3A5JA 2JJDA 2QBRA 3V0DA 4HJQA 5KA0A 3ZV2A 1Q1MA 2Y96A 4ERCA 5GTJA 1SUGA 4BJOA 2HNQA 1PTYA 3S4OA 5KACA 1Q6PA 3AWEA 2CNFA 4NNDA 4ZRTA 3O5XA 1PTTA 5KA8A 2H4GA 2C46A 2H4KA 1JLNA 1M3GA 3ZM3A 2G59A 1P15A 4OHIA 4BPCA 1ZCLA 4GFUA 4RI5A 1OEOX 2I4GA 3S4EA 2I5XA 2OUDA 4JMJA 3GXHA 1L8GA 2HC2A 2B4SA 1PA9A 1T48A 3I36A 5EHRA 4GRZA 3F41A 4GS0A 1JF7A 2F46A 1NWEA 1XRIA 1D5RA 2Q47A 4RH5A 5AWXA 3S3FA 1KAKA 3S3KA 2F6WA 1C85A 3RGQA 5MMZB 1ZCKA 2J17A 3S3HA 1A5YA 3OLRA 2AZRA 2ZMMA 4R30A 1PXHA 5KA2A 5K23A 2P6XA 4QAHA 2VEUA 3QCHA 1OEVA 2F71A 1C83A 3QCKA 2NT2A 4NYHA 1GWZA 3M4UA 2CM7A 1PYNA 3PS5A 4PYHA 1R6HA 2I6OA 1ZZWA 4JMKA 4TVVA 3ZMQA 1OESA 4ICZA 4Y2EA 2VEYA 1G4WR 1U26A 1YWFA 2I3RA 5LXQB 1I9TA 5HDEA 3CWEA 1L8KA 1NZ7A 5BUGA 1VHRA 2RF6A 5IBMA 2P4DA 1YTWA 4Y14A 2BV5A 2HVLA 5BZXA 3V0FA 2Q05A 2CMAA 3QCGA 2GWOA 2WGPA 2B4UA 1T4JA 4I8NA 1ECVA 2PQ5A 3AWFA 1OETA 3ZM0A 4D3QA 5BX1A 3D1HA 3V0IA 1GFYA 4QUNA 2E0TA 1Q6NA 4KYQA 1YN9A 1NO6A 2R0BA 2B4OA 4KYRA 4OHDA 3ZM1A 2OC3A 2QDCA 1I57A 1G7FA 3F9BA
chains in the Genus database with same CATH superfamily
3AWGA 1FGSA 1LQFA 1E8CA 2CNGA 2JFGA 2C7SA 4H34A 3QCMA 2F6VA 2QBPA 5J8RA 3RZ2A 1G1FA 1OHEA 4QBEA 2GC5A 2B3OA 1T49A 3F99A 2WJPA 5BZZA 1FPZA 3I80A 4RH9A 3A5KA 4WU3A 1XXVA 1YZ4A 1ONYA 2VORA 3RGOA 3LJ8A 2CM3A 1QZ0A 3BLTA 5KA7A 5K24A 3MOZA 3V0EA 3SMEA 3GXGA 4RI4A 4OHLA 4GE2A 2FJNA 2Y1OA 2CM8A 4ZI4A 4Z6BA 3CM3A 3NMEA 2H03A 3QCFA 2AHSA 1NWLA 2OZ5A 3D42A 4GE6A 2Y68A 5KABA 2HNPA 1WRMA 5EHPA 1OHDA 3D1OA 1KAVA 2NT7A 3BRHA 4J51A 3QCIA 2I42A 2SHPA 2JFHA 3QCLA 1YFOA 2BGDA 1WCHA 1YGUA 4GRYA 3V0JA 2Y2FA 2HXPA 4WOHA 2FH7A 4DGPA 4D3PA 2PBNA 1G7GA 1XM2A 2M3VA 3EZZA 4GE5A 2VTEA 4R0SA 3MOWA 3QCNA 1Q6JA 3U96A 1YTNA 2VOSA 1BZJA 2I4HA 5KA3A 2BIJA 4JNBA 2AM2A 4OHEA 2PT0A 5IBSA 1OHCA 4MBBA 5K22A 2I6JA 2DXPA 5A5EA 3D1QA 1C88A 2CMBA 2NLKA 2OOQA 1G4US 4B04A 4CVLA 3D9CA 2PSZA 4HJPA 1W7KA 2CFVA 2I6PA 2UUPA 1G1GA 2QBQA 3LK7A 5KAAA 2A8BA 1P3DA 3ZM2A 2H02A 1PH0A 3QKPA 4NWGA 2FJMA 5K25A 4GWFA 4HRFA 2F70A 1FQ1A 4GFVA 1RPMA 2J16A 2QCJA 1NL9A 1JBVA 4OHHA 3PYZA 2NTAA 3F9AA 5KA1A 5M43A 4DGXA 2X5OA 1PA1A 1PTUA 2WTZA 4RHGA 1FPRA 1I9SA 2ZN7A 5KADA 1V3AA 2HB1A 2VEVA 2VEXA 5KA4A 1PTVA 1U24A 3EAXA 2A3KA 1RXDA 3H2XA 4HV4A 2BZLA 1AAXA 1NNYA 4NX8A 1LARA 2GP0A 3QCZA 4CVMA 2CJZA 2CMCA 1WAXA 3EMUA 2HY3A 4PVGA 4CVKA 4RKKA 3RO1A 1C84A 1GQQA 1J4XA 1YGRA 3O4UA 1YPTA 3OMHA 3O4SA 2BGEA 3QKQA 2H04A 5K9VA 1GQYA 2CNIA 3F81A 2QDPA 3O4TA 3SR9A 3S3EA 2F00A 4RDDA 1G1HA 2F6TA 2GC6A 2GJTA 3QCCA 2NZ6A 3ZL8A 4S0GA 4H1OA 1J6UA 3V0GA 2F6YA 2B07A 2I75A 3MMJA 1YTSA 1BZHA 2H4VA 5K9WA 1MKPA 2I6MA 2QCTA 2QDMA 1OEUA 1XXPA 1Q6TA 2J16B 3I7ZA 1Q6MA 2QBSA 1Q6SA 2MBCA 2G6ZA 3O3LA 3QCJA 3N2AA 2NV5A 4D3RA 3EB1A 1QXKA 3BM8A 3HN7A 1GG4A 3BLUA 3QCEA 3EU0A 4YR8B 1X24A 1C86A 3QCDA 2I3UA 1U25A 1C87A 2GCBA 3MVNA 2PI7A 4JBCA 2HC1A 2CNHA 5I6VA 4AZ1A 2ESBA 4QAPA 2B49A 4WU2A 3QCBA 4ZN5A 1EENA 3UAGA 2F6FA 2I1YA 4R0TA 2I6IA 4IKCA 1LYVA 2CNEA 5KA9A 3N0AA 3V0HA 4QBWA 4NWFA 2VEWA 4WTYA 2F6ZA 1ONZA 3ZMPA 2HCMA 2I4EA 4QUMA 2CM2A 1XBOA 3D44A 1OEMX 2IMGA 2QEPA 4KI9A 2PA5A 3B7OA 1EEOA 2B4PA 2YDUA 1BZCA 1ZC0A 4YAAA 3A5JA 4C12A 2Y66A 2XPCA 2JJDA 4QDIA 2QBRA 3V0DA 4HJQA 5KA0A 3ZV2A 1Q1MA 2Y96A 4ERCA 5GTJA 1SUGA 4BJOA 2HNQA 1PTYA 3S4OA 5KACA 2Y67A 1Q6PA 4ZIYA 3AWEA 2CNFA 4NNDA 4ZRTA 3O5XA 1PTTA 5KA8A 2H4GA 2C46A 2H4KA 1JLNA 1M3GA 3ZM3A 2G59A 5A5FA 1P15A 1E0DA 4OHIA 4BPCA 1ZCLA 4GFUA 2XJAA 4RI5A 1OEOX 2I4GA 3S4EA 2I5XA 2UAGA 2OUDA 4JMJA 1O5ZA 4BUCA 3GXHA 1L8GA 2HC2A 2B4SA 1PA9A 2UUOA 1T48A 3I36A 5EHRA 4GRZA 3F41A 2AM1A 4GS0A 1JF7A 2F46A 1NWEA 1XRIA 1D5RA 1EEHA 2Q47A 4RH5A 5AWXA 3S3FA 1KAKA 3S3KA 2F6WA 1C85A 2JFFA 3RGQA 5MMZB 1ZCKA 2J17A 3S3HA 1A5YA 3OLRA 4C13A 2AZRA 2ZMMA 4R30A 1PXHA 5KA2A 5K23A 2P6XA 4QAHA 2VEUA 3QCHA 1OEVA 2F71A 1C83A 3QCKA 2NT2A 4NYHA 1GWZA 3M4UA 1W78A 2CM7A 1PYNA 3PS5A 4PYHA 1R6HA 2VTDA 2I6OA 1ZZWA 4JMKA 4TVVA 3ZMQA 1UAGA 1OESA 4ICZA 3NRSA 4Y2EA 2GCAA 1P31A 1JBWA 2VEYA 1G4WR 1U26A 1YWFA 2I3RA 5LXQB 1I9TA 5HDEA 3CWEA 3ZM6A 1L8KA 1NZ7A 5BUGA 1VHRA 2RF6A 4QF5A 4BUBA 5IBMA 2P4DA 1YTWA 4Y14A 2BV5A 2HVLA 5BZXA 3V0FA 2Q05A 4UAGA 2CMAA 3QCGA 2GWOA 2WGPA 3ZM5A 2B4UA 1T4JA 4I8NA 1ECVA 2PQ5A 3AWFA 1OETA 3ZM0A 4D3QA 5BX1A 3D1HA 3V0IA 1GFYA 4QUNA 2E0TA 1Q6NA 4KYQA 1YN9A 1NO6A 2R0BA 2B4OA 4KYRA 4OHDA 3ZM1A 2OC3A 2QDCA 1I57A 1G7FA 3F9BA
chains in the Genus database with same CATH topology
3AWGA 1LQFA 2CNGA 2C7SA 4H34A 3QCMA 2F6VA 2QBPA 5J8RA 3RZ2A 1G1FA 1OHEA 4QBEA 2B3OA 1T49A 3F99A 5BZZA 1FPZA 3I80A 4RH9A 3A5KA 4WU3A 1XXVA 1YZ4A 1ONYA 3RGOA 3LJ8A 2CM3A 1QZ0A 3BLTA 5KA7A 5K24A 3MOZA 3V0EA 3SMEA 3GXGA 4RI4A 4OHLA 4GE2A 2FJNA 2CM8A 4ZI4A 4Z6BA 3CM3A 3NMEA 2H03A 3QCFA 2AHSA 1NWLA 2OZ5A 3D42A 4GE6A 5KABA 2HNPA 1WRMA 5EHPA 1OHDA 3D1OA 1KAVA 2NT7A 3BRHA 4J51A 3QCIA 2I42A 2SHPA 3QCLA 1YFOA 2BGDA 1WCHA 1YGUA 4GRYA 3V0JA 2Y2FA 2HXPA 4WOHA 2FH7A 4DGPA 4D3PA 2PBNA 1G7GA 1XM2A 2M3VA 3EZZA 4GE5A 4R0SA 3MOWA 3QCNA 1Q6JA 3U96A 1YTNA 1BZJA 2I4HA 5KA3A 2BIJA 4JNBA 4OHEA 2PT0A 5IBSA 1OHCA 4MBBA 5K22A 2I6JA 2DXPA 3D1QA 1C88A 2CMBA 2NLKA 2OOQA 1G4US 4B04A 3D9CA 2PSZA 4HJPA 2CFVA 2I6PA 1G1GA 2QBQA 5KAAA 2A8BA 3ZM2A 2H02A 1PH0A 3QKPA 4NWGA 2FJMA 5K25A 4GWFA 4HRFA 2F70A 1FQ1A 4GFVA 1RPMA 2J16A 2QCJA 1NL9A 4OHHA 2NTAA 3F9AA 5KA1A 5M43A 4DGXA 1PA1A 1PTUA 4RHGA 1FPRA 1I9SA 2ZN7A 5KADA 1V3AA 2HB1A 2VEVA 2VEXA 5KA4A 1PTVA 1U24A 3EAXA 2A3KA 1RXDA 3H2XA 2BZLA 1AAXA 1NNYA 4NX8A 1LARA 2GP0A 2CJZA 2CMCA 1WAXA 3EMUA 2HY3A 4PVGA 4RKKA 3RO1A 1C84A 1J4XA 1YGRA 3O4UA 1YPTA 3OMHA 3O4SA 2BGEA 3QKQA 2H04A 5K9VA 2CNIA 3F81A 2QDPA 3O4TA 3SR9A 3S3EA 4RDDA 1G1HA 2F6TA 2GJTA 3QCCA 2NZ6A 4S0GA 4H1OA 3V0GA 2F6YA 2B07A 2I75A 3MMJA 1YTSA 1BZHA 2H4VA 5K9WA 1MKPA 2I6MA 2QCTA 2QDMA 1OEUA 1XXPA 1Q6TA 2J16B 3I7ZA 1Q6MA 2QBSA 1Q6SA 2MBCA 2G6ZA 3O3LA 3QCJA 2NV5A 4D3RA 3EB1A 1QXKA 3BM8A 3BLUA 3QCEA 3EU0A 4YR8B 1X24A 1C86A 3QCDA 2I3UA 1U25A 1C87A 2PI7A 4JBCA 2HC1A 2CNHA 5I6VA 4AZ1A 2ESBA 4QAPA 2B49A 4WU2A 3QCBA 4ZN5A 1EENA 2F6FA 2I1YA 4R0TA 2I6IA 4IKCA 1LYVA 2CNEA 5KA9A 3N0AA 3V0HA 4QBWA 4NWFA 2VEWA 4WTYA 2F6ZA 1ONZA 3ZMPA 2HCMA 2I4EA 4QUMA 2CM2A 1XBOA 3D44A 1OEMX 2IMGA 2QEPA 4KI9A 2PA5A 3B7OA 1EEOA 2B4PA 2YDUA 1BZCA 1ZC0A 4YAAA 3A5JA 2JJDA 2QBRA 3V0DA 4HJQA 5KA0A 3ZV2A 1Q1MA 2Y96A 4ERCA 5GTJA 1SUGA 4BJOA 2HNQA 1PTYA 3S4OA 5KACA 1Q6PA 3AWEA 2CNFA 4NNDA 4ZRTA 3O5XA 1PTTA 5KA8A 2H4GA 2C46A 2H4KA 1JLNA 1M3GA 3ZM3A 2G59A 1P15A 4OHIA 4BPCA 1ZCLA 4GFUA 4RI5A 1OEOX 2I4GA 3S4EA 2I5XA 2OUDA 4JMJA 3GXHA 1L8GA 2HC2A 2B4SA 1PA9A 1T48A 3I36A 5EHRA 4GRZA 3F41A 4GS0A 1JF7A 2F46A 1NWEA 1XRIA 1D5RA 2Q47A 4RH5A 5AWXA 3S3FA 1KAKA 3S3KA 2F6WA 1C85A 3RGQA 5MMZB 1ZCKA 2J17A 3S3HA 1A5YA 3OLRA 2AZRA 2ZMMA 4R30A 1PXHA 5KA2A 5K23A 2P6XA 4QAHA 2VEUA 3QCHA 1OEVA 2F71A 1C83A 3QCKA 2NT2A 4NYHA 1GWZA 3M4UA 2CM7A 1PYNA 3PS5A 4PYHA 1R6HA 2I6OA 1ZZWA 4JMKA 4TVVA 3ZMQA 1OESA 4ICZA 4Y2EA 2VEYA 1G4WR 1U26A 1YWFA 2I3RA 5LXQB 1I9TA 5HDEA 3CWEA 1L8KA 1NZ7A 5BUGA 1VHRA 2RF6A 5IBMA 2P4DA 1YTWA 4Y14A 2BV5A 2HVLA 5BZXA 3V0FA 2Q05A 2CMAA 3QCGA 2GWOA 2WGPA 2B4UA 1T4JA 4I8NA 1ECVA 2PQ5A 3AWFA 1OETA 3ZM0A 4D3QA 5BX1A 3D1HA 3V0IA 1GFYA 4QUNA 2E0TA 1Q6NA 4KYQA 1YN9A 1NO6A 2R0BA 2B4OA 4KYRA 4OHDA 3ZM1A 2OC3A 2QDCA 1I57A 1G7FA 3F9BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWG A;  1LQF A;  2CNG A;  2C7S A;  4H34 A;  3QCM A;  2F6V A;  2QBP A;  5J8R A;  3RZ2 A;  1G1F A;  1OHE A;  4QBE A;  2B3O A;  1T49 A;  3F99 A;  5BZZ A;  1FPZ A;  3I80 A;  4RH9 A;  3A5K A;  4WU3 A;  1XXV A;  1YZ4 A;  1ONY A;  3RGO A;  3LJ8 A;  2CM3 A;  1QZ0 A;  3BLT A;  5KA7 A;  5K24 A;  3MOZ A;  3V0E A;  3SME A;  3GXG A;  4RI4 A;  4OHL A;  4GE2 A;  2FJN A;  2CM8 A;  4ZI4 A;  4Z6B A;  3CM3 A;  3NME A;  2H03 A;  3QCF A;  2AHS A;  1NWL A;  2OZ5 A;  3D42 A;  4GE6 A;  5KAB A;  2HNP A;  1WRM A;  5EHP A;  1OHD A;  3D1O A;  1KAV A;  2NT7 A;  3BRH A;  4J51 A;  3QCI A;  2I42 A;  2SHP A;  3QCL A;  1YFO A;  2BGD A;  1WCH A;  1YGU A;  4GRY A;  3V0J A;  2Y2F A;  2HXP A;  4WOH A;  2FH7 A;  4DGP A;  4D3P A;  2PBN A;  1G7G A;  1XM2 A;  2M3V A;  3EZZ A;  4GE5 A;  4R0S A;  3MOW A;  3QCN A;  1Q6J A;  3U96 A;  1YTN A;  1BZJ A;  2I4H A;  5KA3 A;  2BIJ A;  4JNB A;  4OHE A;  2PT0 A;  5IBS A;  1OHC A;  4MBB A;  5K22 A;  2I6J A;  2DXP A;  3D1Q A;  1C88 A;  2CMB A;  2NLK A;  2OOQ A;  1G4U S;  4B04 A;  3D9C A;  2PSZ A;  4HJP A;  2CFV A;  2I6P A;  1G1G A;  2QBQ A;  5KAA A;  2A8B A;  3ZM2 A;  2H02 A;  1PH0 A;  3QKP A;  4NWG A;  2FJM A;  5K25 A;  4GWF A;  4HRF A;  2F70 A;  1FQ1 A;  4GFV A;  1RPM A;  2J16 A;  2QCJ A;  1NL9 A;  4OHH A;  2NTA A;  3F9A A;  5KA1 A;  5M43 A;  4DGX A;  1PA1 A;  1PTU A;  4RHG A;  1FPR A;  1I9S A;  2ZN7 A;  5KAD A;  1V3A A;  2HB1 A;  2VEV A;  2VEX A;  5KA4 A;  1PTV A;  1U24 A;  3EAX A;  2A3K A;  1RXD A;  3H2X A;  2BZL A;  1AAX A;  1NNY A;  4NX8 A;  1LAR A;  2GP0 A;  2CJZ A;  2CMC A;  1WAX A;  3EMU A;  2HY3 A;  4PVG A;  4RKK A;  3RO1 A;  1C84 A;  1J4X A;  1YGR A;  3O4U A;  1YPT A;  3OMH A;  3O4S A;  2BGE A;  3QKQ A;  2H04 A;  5K9V A;  2CNI A;  3F81 A;  2QDP A;  3O4T A;  3SR9 A;  3S3E A;  4RDD A;  1G1H A;  2F6T A;  2GJT A;  3QCC A;  2NZ6 A;  4S0G A;  4H1O A;  3V0G A;  2F6Y A;  2B07 A;  2I75 A;  3MMJ A;  1YTS A;  1BZH A;  2H4V A;  5K9W A;  1MKP A;  2I6M A;  2QCT A;  2QDM A;  1OEU A;  1XXP A;  1Q6T A;  2J16 B;  3I7Z A;  1Q6M A;  2QBS A;  1Q6S A;  2MBC A;  2G6Z A;  3O3L A;  3QCJ A;  2NV5 A;  4D3R A;  3EB1 A;  1QXK A;  3BM8 A;  3BLU A;  3QCE A;  3EU0 A;  4YR8 B;  1X24 A;  1C86 A;  3QCD A;  2I3U A;  1U25 A;  1C87 A;  2PI7 A;  4JBC A;  2HC1 A;  2CNH A;  5I6V A;  4AZ1 A;  2ESB A;  4QAP A;  2B49 A;  4WU2 A;  3QCB A;  4ZN5 A;  1EEN A;  2F6F A;  2I1Y A;  4R0T A;  2I6I A;  4IKC A;  1LYV A;  2CNE A;  5KA9 A;  3N0A A;  3V0H A;  4QBW A;  4NWF A;  2VEW A;  4WTY A;  2F6Z A;  1ONZ A;  3ZMP A;  2HCM A;  2I4E A;  4QUM A;  2CM2 A;  1XBO A;  3D44 A;  1OEM X;  2IMG A;  2QEP A;  4KI9 A;  2PA5 A;  3B7O A;  1EEO A;  2B4P A;  2YDU A;  1BZC A;  1ZC0 A;  4YAA A;  3A5J A;  2JJD A;  2QBR A;  3V0D A;  4HJQ A;  5KA0 A;  3ZV2 A;  1Q1M A;  2Y96 A;  4ERC A;  5GTJ A;  1SUG A;  4BJO A;  2HNQ A;  1PTY A;  3S4O A;  5KAC A;  1Q6P A;  3AWE A;  2CNF A;  4NND A;  4ZRT A;  3O5X A;  1PTT A;  5KA8 A;  2H4G A;  2C46 A;  2H4K A;  1JLN A;  1M3G A;  3ZM3 A;  2G59 A;  1P15 A;  4OHI A;  4BPC A;  1ZCL A;  4GFU A;  4RI5 A;  1OEO X;  2I4G A;  3S4E A;  2I5X A;  2OUD A;  4JMJ A;  3GXH A;  1L8G A;  2HC2 A;  2B4S A;  1PA9 A;  1T48 A;  3I36 A;  5EHR A;  4GRZ A;  3F41 A;  4GS0 A;  1JF7 A;  2F46 A;  1NWE A;  1XRI A;  1D5R A;  2Q47 A;  4RH5 A;  5AWX A;  3S3F A;  1KAK A;  3S3K A;  2F6W A;  1C85 A;  3RGQ A;  5MMZ B;  1ZCK A;  2J17 A;  3S3H A;  1A5Y A;  3OLR A;  2AZR A;  2ZMM A;  4R30 A;  1PXH A;  5KA2 A;  5K23 A;  2P6X A;  4QAH A;  2VEU A;  3QCH A;  1OEV A;  2F71 A;  1C83 A;  3QCK A;  2NT2 A;  4NYH A;  1GWZ A;  3M4U A;  2CM7 A;  1PYN A;  3PS5 A;  4PYH A;  1R6H A;  2I6O A;  1ZZW A;  4JMK A;  4TVV A;  3ZMQ A;  1OES A;  4ICZ A;  4Y2E A;  2VEY A;  1G4W R;  1U26 A;  1YWF A;  2I3R A;  5LXQ B;  1I9T A;  5HDE A;  3CWE A;  1L8K A;  1NZ7 A;  5BUG A;  1VHR A;  2RF6 A;  5IBM A;  2P4D A;  1YTW A;  4Y14 A;  2BV5 A;  2HVL A;  5BZX A;  3V0F A;  2Q05 A;  2CMA A;  3QCG A;  2GWO A;  2WGP A;  2B4U A;  1T4J A;  4I8N A;  1ECV A;  2PQ5 A;  3AWF A;  1OET A;  3ZM0 A;  4D3Q A;  5BX1 A;  3D1H A;  3V0I A;  1GFY A;  4QUN A;  2E0T A;  1Q6N A;  4KYQ A;  1YN9 A;  1NO6 A;  2R0B A;  2B4O A;  4KYR A;  4OHD A;  3ZM1 A;  2OC3 A;  2QDC A;  1I57 A;  1G7F A;  3F9B A; 
#chains in the Genus database with same CATH topology
 3AWG A;  1FGS A;  1LQF A;  1E8C A;  2CNG A;  2JFG A;  2C7S A;  4H34 A;  3QCM A;  2F6V A;  2QBP A;  5J8R A;  3RZ2 A;  1G1F A;  1OHE A;  4QBE A;  2GC5 A;  2B3O A;  1T49 A;  3F99 A;  2WJP A;  5BZZ A;  1FPZ A;  3I80 A;  4RH9 A;  3A5K A;  4WU3 A;  1XXV A;  1YZ4 A;  1ONY A;  2VOR A;  3RGO A;  3LJ8 A;  2CM3 A;  1QZ0 A;  3BLT A;  5KA7 A;  5K24 A;  3MOZ A;  3V0E A;  3SME A;  3GXG A;  4RI4 A;  4OHL A;  4GE2 A;  2FJN A;  2Y1O A;  2CM8 A;  4ZI4 A;  4Z6B A;  3CM3 A;  3NME A;  2H03 A;  3QCF A;  2AHS A;  1NWL A;  2OZ5 A;  3D42 A;  4GE6 A;  2Y68 A;  5KAB A;  2HNP A;  1WRM A;  5EHP A;  1OHD A;  3D1O A;  1KAV A;  2NT7 A;  3BRH A;  4J51 A;  3QCI A;  2I42 A;  2SHP A;  2JFH A;  3QCL A;  1YFO A;  2BGD A;  1WCH A;  1YGU A;  4GRY A;  3V0J A;  2Y2F A;  2HXP A;  4WOH A;  2FH7 A;  4DGP A;  4D3P A;  2PBN A;  1G7G A;  1XM2 A;  2M3V A;  3EZZ A;  4GE5 A;  2VTE A;  4R0S A;  3MOW A;  3QCN A;  1Q6J A;  3U96 A;  1YTN A;  2VOS A;  1BZJ A;  2I4H A;  5KA3 A;  2BIJ A;  4JNB A;  2AM2 A;  4OHE A;  2PT0 A;  5IBS A;  1OHC A;  4MBB A;  5K22 A;  2I6J A;  2DXP A;  5A5E A;  3D1Q A;  1C88 A;  2CMB A;  2NLK A;  2OOQ A;  1G4U S;  4B04 A;  4CVL A;  3D9C A;  2PSZ A;  4HJP A;  1W7K A;  2CFV A;  2I6P A;  2UUP A;  1G1G A;  2QBQ A;  3LK7 A;  5KAA A;  2A8B A;  1P3D A;  3ZM2 A;  2H02 A;  1PH0 A;  3QKP A;  4NWG A;  2FJM A;  5K25 A;  4GWF A;  4HRF A;  2F70 A;  1FQ1 A;  4GFV A;  1RPM A;  2J16 A;  2QCJ A;  1NL9 A;  1JBV A;  4OHH A;  3PYZ A;  2NTA A;  3F9A A;  5KA1 A;  5M43 A;  4DGX A;  2X5O A;  1PA1 A;  1PTU A;  2WTZ A;  4RHG A;  1FPR A;  1I9S A;  2ZN7 A;  5KAD A;  1V3A A;  2HB1 A;  2VEV A;  2VEX A;  5KA4 A;  1PTV A;  1U24 A;  3EAX A;  2A3K A;  1RXD A;  3H2X A;  4HV4 A;  2BZL A;  1AAX A;  1NNY A;  4NX8 A;  1LAR A;  2GP0 A;  3QCZ A;  4CVM A;  2CJZ A;  2CMC A;  1WAX A;  3EMU A;  2HY3 A;  4PVG A;  4CVK A;  4RKK A;  3RO1 A;  1C84 A;  1GQQ A;  1J4X A;  1YGR A;  3O4U A;  1YPT A;  3OMH A;  3O4S A;  2BGE A;  3QKQ A;  2H04 A;  5K9V A;  1GQY A;  2CNI A;  3F81 A;  2QDP A;  3O4T A;  3SR9 A;  3S3E A;  2F00 A;  4RDD A;  1G1H A;  2F6T A;  2GC6 A;  2GJT A;  3QCC A;  2NZ6 A;  3ZL8 A;  4S0G A;  4H1O A;  1J6U A;  3V0G A;  2F6Y A;  2B07 A;  2I75 A;  3MMJ A;  1YTS A;  1BZH A;  2H4V A;  5K9W A;  1MKP A;  2I6M A;  2QCT A;  2QDM A;  1OEU A;  1XXP A;  1Q6T A;  2J16 B;  3I7Z A;  1Q6M A;  2QBS A;  1Q6S A;  2MBC A;  2G6Z A;  3O3L A;  3QCJ A;  3N2A A;  2NV5 A;  4D3R A;  3EB1 A;  1QXK A;  3BM8 A;  3HN7 A;  1GG4 A;  3BLU A;  3QCE A;  3EU0 A;  4YR8 B;  1X24 A;  1C86 A;  3QCD A;  2I3U A;  1U25 A;  1C87 A;  2GCB A;  3MVN A;  2PI7 A;  4JBC A;  2HC1 A;  2CNH A;  5I6V A;  4AZ1 A;  2ESB A;  4QAP A;  2B49 A;  4WU2 A;  3QCB A;  4ZN5 A;  1EEN A;  3UAG A;  2F6F A;  2I1Y A;  4R0T A;  2I6I A;  4IKC A;  1LYV A;  2CNE A;  5KA9 A;  3N0A A;  3V0H A;  4QBW A;  4NWF A;  2VEW A;  4WTY A;  2F6Z A;  1ONZ A;  3ZMP A;  2HCM A;  2I4E A;  4QUM A;  2CM2 A;  1XBO A;  3D44 A;  1OEM X;  2IMG A;  2QEP A;  4KI9 A;  2PA5 A;  3B7O A;  1EEO A;  2B4P A;  2YDU A;  1BZC A;  1ZC0 A;  4YAA A;  3A5J A;  4C12 A;  2Y66 A;  2XPC A;  2JJD A;  4QDI A;  2QBR A;  3V0D A;  4HJQ A;  5KA0 A;  3ZV2 A;  1Q1M A;  2Y96 A;  4ERC A;  5GTJ A;  1SUG A;  4BJO A;  2HNQ A;  1PTY A;  3S4O A;  5KAC A;  2Y67 A;  1Q6P A;  4ZIY A;  3AWE A;  2CNF A;  4NND A;  4ZRT A;  3O5X A;  1PTT A;  5KA8 A;  2H4G A;  2C46 A;  2H4K A;  1JLN A;  1M3G A;  3ZM3 A;  2G59 A;  5A5F A;  1P15 A;  1E0D A;  4OHI A;  4BPC A;  1ZCL A;  4GFU A;  2XJA A;  4RI5 A;  1OEO X;  2I4G A;  3S4E A;  2I5X A;  2UAG A;  2OUD A;  4JMJ A;  1O5Z A;  4BUC A;  3GXH A;  1L8G A;  2HC2 A;  2B4S A;  1PA9 A;  2UUO A;  1T48 A;  3I36 A;  5EHR A;  4GRZ A;  3F41 A;  2AM1 A;  4GS0 A;  1JF7 A;  2F46 A;  1NWE A;  1XRI A;  1D5R A;  1EEH A;  2Q47 A;  4RH5 A;  5AWX A;  3S3F A;  1KAK A;  3S3K A;  2F6W A;  1C85 A;  2JFF A;  3RGQ A;  5MMZ B;  1ZCK A;  2J17 A;  3S3H A;  1A5Y A;  3OLR A;  4C13 A;  2AZR A;  2ZMM A;  4R30 A;  1PXH A;  5KA2 A;  5K23 A;  2P6X A;  4QAH A;  2VEU A;  3QCH A;  1OEV A;  2F71 A;  1C83 A;  3QCK A;  2NT2 A;  4NYH A;  1GWZ A;  3M4U A;  1W78 A;  2CM7 A;  1PYN A;  3PS5 A;  4PYH A;  1R6H A;  2VTD A;  2I6O A;  1ZZW A;  4JMK A;  4TVV A;  3ZMQ A;  1UAG A;  1OES A;  4ICZ A;  3NRS A;  4Y2E A;  2GCA A;  1P31 A;  1JBW A;  2VEY A;  1G4W R;  1U26 A;  1YWF A;  2I3R A;  5LXQ B;  1I9T A;  5HDE A;  3CWE A;  3ZM6 A;  1L8K A;  1NZ7 A;  5BUG A;  1VHR A;  2RF6 A;  4QF5 A;  4BUB A;  5IBM A;  2P4D A;  1YTW A;  4Y14 A;  2BV5 A;  2HVL A;  5BZX A;  3V0F A;  2Q05 A;  4UAG A;  2CMA A;  3QCG A;  2GWO A;  2WGP A;  3ZM5 A;  2B4U A;  1T4J A;  4I8N A;  1ECV A;  2PQ5 A;  3AWF A;  1OET A;  3ZM0 A;  4D3Q A;  5BX1 A;  3D1H A;  3V0I A;  1GFY A;  4QUN A;  2E0T A;  1Q6N A;  4KYQ A;  1YN9 A;  1NO6 A;  2R0B A;  2B4O A;  4KYR A;  4OHD A;  3ZM1 A;  2OC3 A;  2QDC A;  1I57 A;  1G7F A;  3F9B A; 
#chains in the Genus database with same CATH homology
 3AWG A;  1LQF A;  2CNG A;  2C7S A;  4H34 A;  3QCM A;  2F6V A;  2QBP A;  5J8R A;  3RZ2 A;  1G1F A;  1OHE A;  4QBE A;  2B3O A;  1T49 A;  3F99 A;  5BZZ A;  1FPZ A;  3I80 A;  4RH9 A;  3A5K A;  4WU3 A;  1XXV A;  1YZ4 A;  1ONY A;  3RGO A;  3LJ8 A;  2CM3 A;  1QZ0 A;  3BLT A;  5KA7 A;  5K24 A;  3MOZ A;  3V0E A;  3SME A;  3GXG A;  4RI4 A;  4OHL A;  4GE2 A;  2FJN A;  2CM8 A;  4ZI4 A;  4Z6B A;  3CM3 A;  3NME A;  2H03 A;  3QCF A;  2AHS A;  1NWL A;  2OZ5 A;  3D42 A;  4GE6 A;  5KAB A;  2HNP A;  1WRM A;  5EHP A;  1OHD A;  3D1O A;  1KAV A;  2NT7 A;  3BRH A;  4J51 A;  3QCI A;  2I42 A;  2SHP A;  3QCL A;  1YFO A;  2BGD A;  1WCH A;  1YGU A;  4GRY A;  3V0J A;  2Y2F A;  2HXP A;  4WOH A;  2FH7 A;  4DGP A;  4D3P A;  2PBN A;  1G7G A;  1XM2 A;  2M3V A;  3EZZ A;  4GE5 A;  4R0S A;  3MOW A;  3QCN A;  1Q6J A;  3U96 A;  1YTN A;  1BZJ A;  2I4H A;  5KA3 A;  2BIJ A;  4JNB A;  4OHE A;  2PT0 A;  5IBS A;  1OHC A;  4MBB A;  5K22 A;  2I6J A;  2DXP A;  3D1Q A;  1C88 A;  2CMB A;  2NLK A;  2OOQ A;  1G4U S;  4B04 A;  3D9C A;  2PSZ A;  4HJP A;  2CFV A;  2I6P A;  1G1G A;  2QBQ A;  5KAA A;  2A8B A;  3ZM2 A;  2H02 A;  1PH0 A;  3QKP A;  4NWG A;  2FJM A;  5K25 A;  4GWF A;  4HRF A;  2F70 A;  1FQ1 A;  4GFV A;  1RPM A;  2J16 A;  2QCJ A;  1NL9 A;  4OHH A;  2NTA A;  3F9A A;  5KA1 A;  5M43 A;  4DGX A;  1PA1 A;  1PTU A;  4RHG A;  1FPR A;  1I9S A;  2ZN7 A;  5KAD A;  1V3A A;  2HB1 A;  2VEV A;  2VEX A;  5KA4 A;  1PTV A;  1U24 A;  3EAX A;  2A3K A;  1RXD A;  3H2X A;  2BZL A;  1AAX A;  1NNY A;  4NX8 A;  1LAR A;  2GP0 A;  2CJZ A;  2CMC A;  1WAX A;  3EMU A;  2HY3 A;  4PVG A;  4RKK A;  3RO1 A;  1C84 A;  1J4X A;  1YGR A;  3O4U A;  1YPT A;  3OMH A;  3O4S A;  2BGE A;  3QKQ A;  2H04 A;  5K9V A;  2CNI A;  3F81 A;  2QDP A;  3O4T A;  3SR9 A;  3S3E A;  4RDD A;  1G1H A;  2F6T A;  2GJT A;  3QCC A;  2NZ6 A;  4S0G A;  4H1O A;  3V0G A;  2F6Y A;  2B07 A;  2I75 A;  3MMJ A;  1YTS A;  1BZH A;  2H4V A;  5K9W A;  1MKP A;  2I6M A;  2QCT A;  2QDM A;  1OEU A;  1XXP A;  1Q6T A;  2J16 B;  3I7Z A;  1Q6M A;  2QBS A;  1Q6S A;  2MBC A;  2G6Z A;  3O3L A;  3QCJ A;  2NV5 A;  4D3R A;  3EB1 A;  1QXK A;  3BM8 A;  3BLU A;  3QCE A;  3EU0 A;  4YR8 B;  1X24 A;  1C86 A;  3QCD A;  2I3U A;  1U25 A;  1C87 A;  2PI7 A;  4JBC A;  2HC1 A;  2CNH A;  5I6V A;  4AZ1 A;  2ESB A;  4QAP A;  2B49 A;  4WU2 A;  3QCB A;  4ZN5 A;  1EEN A;  2F6F A;  2I1Y A;  4R0T A;  2I6I A;  4IKC A;  1LYV A;  2CNE A;  5KA9 A;  3N0A A;  3V0H A;  4QBW A;  4NWF A;  2VEW A;  4WTY A;  2F6Z A;  1ONZ A;  3ZMP A;  2HCM A;  2I4E A;  4QUM A;  2CM2 A;  1XBO A;  3D44 A;  1OEM X;  2IMG A;  2QEP A;  4KI9 A;  2PA5 A;  3B7O A;  1EEO A;  2B4P A;  2YDU A;  1BZC A;  1ZC0 A;  4YAA A;  3A5J A;  2JJD A;  2QBR A;  3V0D A;  4HJQ A;  5KA0 A;  3ZV2 A;  1Q1M A;  2Y96 A;  4ERC A;  5GTJ A;  1SUG A;  4BJO A;  2HNQ A;  1PTY A;  3S4O A;  5KAC A;  1Q6P A;  3AWE A;  2CNF A;  4NND A;  4ZRT A;  3O5X A;  1PTT A;  5KA8 A;  2H4G A;  2C46 A;  2H4K A;  1JLN A;  1M3G A;  3ZM3 A;  2G59 A;  1P15 A;  4OHI A;  4BPC A;  1ZCL A;  4GFU A;  4RI5 A;  1OEO X;  2I4G A;  3S4E A;  2I5X A;  2OUD A;  4JMJ A;  3GXH A;  1L8G A;  2HC2 A;  2B4S A;  1PA9 A;  1T48 A;  3I36 A;  5EHR A;  4GRZ A;  3F41 A;  4GS0 A;  1JF7 A;  2F46 A;  1NWE A;  1XRI A;  1D5R A;  2Q47 A;  4RH5 A;  5AWX A;  3S3F A;  1KAK A;  3S3K A;  2F6W A;  1C85 A;  3RGQ A;  5MMZ B;  1ZCK A;  2J17 A;  3S3H A;  1A5Y A;  3OLR A;  2AZR A;  2ZMM A;  4R30 A;  1PXH A;  5KA2 A;  5K23 A;  2P6X A;  4QAH A;  2VEU A;  3QCH A;  1OEV A;  2F71 A;  1C83 A;  3QCK A;  2NT2 A;  4NYH A;  1GWZ A;  3M4U A;  2CM7 A;  1PYN A;  3PS5 A;  4PYH A;  1R6H A;  2I6O A;  1ZZW A;  4JMK A;  4TVV A;  3ZMQ A;  1OES A;  4ICZ A;  4Y2E A;  2VEY A;  1G4W R;  1U26 A;  1YWF A;  2I3R A;  5LXQ B;  1I9T A;  5HDE A;  3CWE A;  1L8K A;  1NZ7 A;  5BUG A;  1VHR A;  2RF6 A;  5IBM A;  2P4D A;  1YTW A;  4Y14 A;  2BV5 A;  2HVL A;  5BZX A;  3V0F A;  2Q05 A;  2CMA A;  3QCG A;  2GWO A;  2WGP A;  2B4U A;  1T4J A;  4I8N A;  1ECV A;  2PQ5 A;  3AWF A;  1OET A;  3ZM0 A;  4D3Q A;  5BX1 A;  3D1H A;  3V0I A;  1GFY A;  4QUN A;  2E0T A;  1Q6N A;  4KYQ A;  1YN9 A;  1NO6 A;  2R0B A;  2B4O A;  4KYR A;  4OHD A;  3ZM1 A;  2OC3 A;  2QDC A;  1I57 A;  1G7F A;  3F9B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...