5K9WA

Protein tyrosine phosphatase 1b (1-301) in complex with tcs401, closed state
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
298
structure length
298
Chain Sequence
SMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 108
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5k9wA00
3EB1A 1Q6NA 2VEYA 1X24A 3B7OA 5EHRA 4KYRA 3A5KA 1ZCKA 2I3RA 2CM7A 1C84A 3QCDA 1G4WR 1LYVA 2CNEA 2GJTA 2C7SA 4Y2EA 4D3RA 1OEMX 4KI9A 3RGQA 1YTNA 3D1OA 4GRYA 1D5RA 1XBOA 2NV5A 4JMJA 3AWGA 2H03A 4BJOA 2HNPA 2RF6A 1EENA 2I5XA 1QXKA 5KACA 2ZN7A 2ESBA 1NZ7A 2I6PA 1BZCA 2C46A 1YPTA 2I3UA 3S3HA 4GS0A 3D9CA 1L8KA 3QKPA 2A3KA 2OOQA 4D3PA 3QCCA 1ONZA 2I4EA 3QCKA 4GE5A 1C83A 1ZZWA 2CMBA 2PSZA 5BUGA 1VHRA 2A8BA 4RKKA 2F6FA 2HXPA 2QDCA 1SUGA 2QBRA 1A5YA 4NWGA 5BZZA 2OZ5A 2OUDA 5KA8A 4WTYA 2HB1A 5M43A 2F46A 1ZC0A 1C86A 3EMUA 4R0SA 2BGDA 1KAKA 2I6IA 2PBNA 2BIJA 1OEVA 2PQ5A 1RPMA 1G7GA 1RXDA 1C87A 4GWFA 2CNGA 3O5XA 1YWFA 3AWEA 3ZM1A 4HJQA 1PXHA 5K9VA 2Y2FA 1P15A 2H4KA 4DGXA 4ZI4A 1ONYA 3EAXA 4BPCA 1FPZA 1OHEA 5K9WA 4HJPA 4NWFA 1Q6PA 2NLKA 3S4EA 4B04A 1GFYA 2QBPA 2P4DA 1OESA 5K24A 2YDUA 2I1YA 4JMKA 4R30A 3D44A 4RHGA 2CMCA 2B49A 4QAPA 1XRIA 1OHDA 3QCLA 5HDEA 4WOHA 1FQ1A 1U25A 2B4PA 2F71A 2HNQA 2QBSA 3U96A 5KA0A 3V0JA 1LQFA 4QAHA 4OHDA 5BX1A 1XXPA 2J16B 3RO1A 2VEVA 4D3QA 4QBWA 1PH0A 1JLNA 2HC1A 1KAVA 2PT0A 3ZV2A 1NWEA 1XXVA 2PA5A 3H2XA 2R0BA 2H04A 3CM3A 1T49A 4WU3A 5KADA 1XM2A 4OHEA 1BZJA 2NT7A 5BZXA 2Y96A 1PTVA 1C88A 2F6VA 1T4JA 2FJNA 4I8NA 2B3OA 1I57A 5LXQB 4PYHA 2BZLA 1ECVA 2MBCA 5GTJA 2CM2A 3QCGA 4RH9A 2VEWA 3RGOA 1EEOA 1V3AA 3GXHA 5J8RA 2QEPA 5MMZB 1I9SA 4J51A 2QBQA 4H34A 2NZ6A 3A5JA 4GFUA 1OHCA 4Z6BA 4NNDA 1QZ0A 2WGPA 3O4UA 3V0DA 3MMJA 1Q6TA 3M4UA 2I6JA 1PTYA 2J17A 1WAXA 5KA9A 1ZCLA 1OEUA 4GE6A 1Q6JA 2Q47A 3I36A 1L8GA 4YR8B 3ZM3A 3ZM2A 1YGUA 1WCHA 4YAAA 2P6XA 1NO6A 2I42A 4ERCA 2QDPA 1PTTA 4GFVA 4DGPA 1PTUA 4QUNA 5K22A 3O3LA 3V0FA 3S3FA 1PA9A 2CNIA 2VEUA 4OHIA 4RDDA 4ZRTA 1R6HA 2G59A 5IBMA 2VEXA 4AZ1A 2AZRA 3V0HA 3ZM0A 4TVVA 2IMGA 2CJZA 5AWXA 3F41A 2BGEA 5KA7A 5KA4A 3QCMA 1YZ4A 3V0GA 1G1GA 1T48A 3I80A 4OHHA 5K23A 4HRFA 1YN9A 2I6MA 4IKCA 2FH7A 1U24A 2OC3A 3D42A 3LJ8A 2CM8A 3F9AA 3V0IA 4NX8A 3I7ZA 2QDMA 2GP0A 5IBSA 2H4GA 5EHPA 2I75A 2AHSA 2GWOA 2F70A 3D1HA 2F6ZA 2H02A 1I9TA 1OETA 3SR9A 1GWZA 1MKPA 2NT2A 3QKQA 4ICZA 5KABA 2B4OA 1C85A 2HVLA 1OEOX 2CFVA 3EZZA 4PVGA 1G4US 4MBBA 3BM8A 3S3EA 1U26A 2NTAA 2BV5A 1G7FA 1LARA 2F6WA 3O4TA 1JF7A 5I6VA 3S4OA 1PYNA 3GXGA 3QCEA 3ZMQA 3QCJA 4H1OA 2J16A 1M3GA 2DXPA 4GE2A 1FPRA 4JNBA 3PS5A 1Q6SA 3V0EA 2B4SA 5K25A 2SHPA 4QUMA 2B07A 3D1QA 3BLTA 4RI4A 2I4GA 1YTWA 1YTSA 3QCIA 3QCBA 2CM3A 2CMAA 2HC2A 3MOWA 3BLUA 3OMHA 4GRZA 2B4UA 2HCMA 3QCNA 2CNFA 3MOZA 3O4SA 2Q05A 3QCFA 3N0AA 3NMEA 3F81A 2QCJA 3BRHA 1J4XA 3F9BA 3QCHA 2F6TA 2M3VA 4WU2A 1YGRA 1G1HA 4R0TA 2F6YA 3F99A 1G1FA 3OLRA 5KA1A 2G6ZA 4ZN5A 3SMEA 3CWEA 2QCTA 4RI5A 3ZMPA 1AAXA 4RH5A 4QBEA 4Y14A 1PA1A 4S0GA 1NL9A 2JJDA 2H4VA 5KA3A 2E0TA 2HY3A 4NYHA 2I4HA 3EU0A 1YFOA 3RZ2A 2CNHA 4KYQA 4JBCA 1WRMA 2PI7A 2ZMMA 2FJMA 1NWLA 1Q1MA 2I6OA 1NNYA 5KA2A 4OHLA 3AWFA 1Q6MA 3S3KA 5KAAA 1BZHA
chains in the Genus database with same CATH superfamily
3EB1A 1Q6NA 2VEYA 1X24A 3B7OA 5EHRA 4KYRA 3A5KA 1ZCKA 2I3RA 2CM7A 1C84A 1J6UA 3QCDA 1G4WR 2Y68A 1LYVA 2CNEA 2GJTA 2C7SA 4Y2EA 4D3RA 1OEMX 4KI9A 3RGQA 1YTNA 3D1OA 4GRYA 1D5RA 1XBOA 2NV5A 4JMJA 3AWGA 3N2AA 2H03A 4BJOA 2HNPA 2RF6A 1UAGA 2GC5A 1EENA 2I5XA 1QXKA 5KACA 2ZN7A 2ESBA 3QCZA 1NZ7A 2I6PA 1BZCA 2C46A 1YPTA 2I3UA 3S3HA 4GS0A 2AM1A 3D9CA 1L8KA 3QKPA 2A3KA 2JFHA 2OOQA 4D3PA 3QCCA 3PYZA 1ONZA 2I4EA 3QCKA 4GE5A 1C83A 1ZZWA 2CMBA 2PSZA 5BUGA 1VHRA 2A8BA 4RKKA 1P3DA 2F6FA 3LK7A 2HXPA 2QDCA 1SUGA 2QBRA 1A5YA 4NWGA 5BZZA 2OZ5A 2OUDA 2JFGA 5KA8A 4WTYA 2HB1A 5M43A 1GQQA 2F46A 2GCBA 4CVMA 1ZC0A 1C86A 3EMUA 4R0SA 2BGDA 1KAKA 2I6IA 2PBNA 2VTDA 2BIJA 1OEVA 3ZM6A 2PQ5A 1RPMA 1G7GA 1RXDA 1C87A 4GWFA 2CNGA 3O5XA 1YWFA 2XJAA 3AWEA 3ZM1A 4HJQA 1PXHA 5K9VA 2Y2FA 1P15A 4BUBA 2H4KA 4DGXA 4ZI4A 1ONYA 3EAXA 4BPCA 2Y1OA 1FPZA 1OHEA 2AM2A 2GC6A 5K9WA 4HJPA 4NWFA 1Q6PA 2NLKA 3S4EA 4B04A 1GFYA 2QBPA 2P4DA 4ZIYA 1OESA 5K24A 2YDUA 2I1YA 4JMKA 4R30A 3D44A 4RHGA 2CMCA 2B49A 4QAPA 1XRIA 1EEHA 1OHDA 3HN7A 3QCLA 5HDEA 4WOHA 1FQ1A 2XPCA 1U25A 2B4PA 2F71A 3UAGA 2HNQA 2QBSA 3U96A 5KA0A 3V0JA 1LQFA 4QAHA 4OHDA 5BX1A 1XXPA 2J16B 3RO1A 2JFFA 2VEVA 4QBWA 2VOSA 4D3QA 1PH0A 1JLNA 2HC1A 1KAVA 2PT0A 3ZV2A 1NWEA 1XXVA 2PA5A 3H2XA 2R0BA 3ZL8A 1FGSA 2H04A 3CM3A 4QF5A 1T49A 4WU3A 5KADA 1XM2A 4OHEA 1BZJA 2NT7A 1GQYA 5BZXA 2Y96A 1PTVA 1C88A 3ZM5A 2F6VA 1T4JA 1W7KA 2FJNA 4I8NA 2B3OA 1I57A 5LXQB 4PYHA 2BZLA 1ECVA 2MBCA 5GTJA 4HV4A 2GCAA 1E8CA 2CM2A 4CVKA 3QCGA 4RH9A 2VEWA 2UUOA 3RGOA 1JBVA 1EEOA 1V3AA 3GXHA 5J8RA 2QEPA 1GG4A 5MMZB 1I9SA 4J51A 2QBQA 2VORA 4H34A 2UUPA 2NZ6A 3A5JA 4GFUA 1OHCA 4Z6BA 2F00A 4NNDA 1QZ0A 2Y67A 2WGPA 3O4UA 3V0DA 2VTEA 3MMJA 1Q6TA 3M4UA 2I6JA 1PTYA 2J17A 1WAXA 5KA9A 1ZCLA 1OEUA 2Y66A 4GE6A 1Q6JA 2Q47A 2WJPA 3I36A 1L8GA 4YR8B 3ZM3A 4C13A 3ZM2A 1YGUA 1WCHA 4YAAA 2P6XA 1NO6A 2I42A 4ERCA 2QDPA 1PTTA 4GFVA 4DGPA 1PTUA 4QUNA 5K22A 3O3LA 3V0FA 2X5OA 3S3FA 1PA9A 2CNIA 2VEUA 4OHIA 4RDDA 4ZRTA 1R6HA 2G59A 5IBMA 2VEXA 4AZ1A 2AZRA 3V0HA 3ZM0A 4TVVA 2IMGA 4QDIA 2CJZA 5AWXA 3F41A 2BGEA 5KA7A 5KA4A 3QCMA 1YZ4A 3V0GA 1G1GA 1T48A 3I80A 4OHHA 5K23A 4HRFA 4BUCA 1YN9A 2I6MA 4IKCA 2FH7A 1U24A 1O5ZA 2OC3A 5A5FA 3D42A 3LJ8A 2CM8A 3F9AA 3V0IA 1P31A 4NX8A 1JBWA 3I7ZA 2QDMA 2GP0A 2UAGA 5IBSA 2H4GA 5EHPA 2I75A 2AHSA 2GWOA 2F70A 3D1HA 2F6ZA 2H02A 1I9TA 1OETA 3SR9A 1GWZA 1MKPA 2NT2A 3QKQA 4ICZA 5KABA 1E0DA 3MVNA 2B4OA 1C85A 2HVLA 1OEOX 2CFVA 3EZZA 4PVGA 1G4US 4MBBA 3BM8A 3S3EA 1U26A 2NTAA 2BV5A 1G7FA 1LARA 2F6WA 3O4TA 5A5EA 1JF7A 5I6VA 3S4OA 1PYNA 3GXGA 3QCEA 3ZMQA 4C12A 3QCJA 4H1OA 2J16A 1M3GA 2DXPA 4GE2A 1FPRA 4JNBA 2WTZA 3PS5A 1Q6SA 3V0EA 2B4SA 5K25A 2SHPA 4QUMA 2B07A 3D1QA 3BLTA 4RI4A 4UAGA 2I4GA 1YTWA 1YTSA 3QCIA 3QCBA 2CM3A 2CMAA 2HC2A 3MOWA 3BLUA 3OMHA 4GRZA 2B4UA 2HCMA 3QCNA 2CNFA 3MOZA 3O4SA 2Q05A 3QCFA 3N0AA 3NMEA 3F81A 2QCJA 3BRHA 1J4XA 3F9BA 3QCHA 2F6TA 2M3VA 4WU2A 1YGRA 1G1HA 4R0TA 2F6YA 3F99A 1G1FA 3OLRA 5KA1A 2G6ZA 4ZN5A 3SMEA 3CWEA 2QCTA 4RI5A 3ZMPA 1AAXA 4RH5A 4QBEA 4Y14A 1PA1A 4S0GA 1NL9A 3NRSA 2JJDA 2H4VA 5KA3A 2E0TA 2HY3A 4NYHA 2I4HA 3EU0A 1YFOA 3RZ2A 2CNHA 4KYQA 4JBCA 1WRMA 2PI7A 2ZMMA 2FJMA 1NWLA 1Q1MA 2I6OA 1NNYA 5KA2A 4OHLA 1W78A 3AWFA 1Q6MA 4CVLA 3S3KA 5KAAA 1BZHA
chains in the Genus database with same CATH topology
3EB1A 1Q6NA 2VEYA 1X24A 3B7OA 5EHRA 4KYRA 3A5KA 1ZCKA 2I3RA 2CM7A 1C84A 3QCDA 1G4WR 1LYVA 2CNEA 2GJTA 2C7SA 4Y2EA 4D3RA 1OEMX 4KI9A 3RGQA 1YTNA 3D1OA 4GRYA 1D5RA 1XBOA 2NV5A 4JMJA 3AWGA 2H03A 4BJOA 2HNPA 2RF6A 1EENA 2I5XA 1QXKA 5KACA 2ZN7A 2ESBA 1NZ7A 2I6PA 1BZCA 2C46A 1YPTA 2I3UA 3S3HA 4GS0A 3D9CA 1L8KA 3QKPA 2A3KA 2OOQA 4D3PA 3QCCA 1ONZA 2I4EA 3QCKA 4GE5A 1C83A 1ZZWA 2CMBA 2PSZA 5BUGA 1VHRA 2A8BA 4RKKA 2F6FA 2HXPA 2QDCA 1SUGA 2QBRA 1A5YA 4NWGA 5BZZA 2OZ5A 2OUDA 5KA8A 4WTYA 2HB1A 5M43A 2F46A 1ZC0A 1C86A 3EMUA 4R0SA 2BGDA 1KAKA 2I6IA 2PBNA 2BIJA 1OEVA 2PQ5A 1RPMA 1G7GA 1RXDA 1C87A 4GWFA 2CNGA 3O5XA 1YWFA 3AWEA 3ZM1A 4HJQA 1PXHA 5K9VA 2Y2FA 1P15A 2H4KA 4DGXA 4ZI4A 1ONYA 3EAXA 4BPCA 1FPZA 1OHEA 5K9WA 4HJPA 4NWFA 1Q6PA 2NLKA 3S4EA 4B04A 1GFYA 2QBPA 2P4DA 1OESA 5K24A 2YDUA 2I1YA 4JMKA 4R30A 3D44A 4RHGA 2CMCA 2B49A 4QAPA 1XRIA 1OHDA 3QCLA 5HDEA 4WOHA 1FQ1A 1U25A 2B4PA 2F71A 2HNQA 2QBSA 3U96A 5KA0A 3V0JA 1LQFA 4QAHA 4OHDA 5BX1A 1XXPA 2J16B 3RO1A 2VEVA 4D3QA 4QBWA 1PH0A 1JLNA 2HC1A 1KAVA 2PT0A 3ZV2A 1NWEA 1XXVA 2PA5A 3H2XA 2R0BA 2H04A 3CM3A 1T49A 4WU3A 5KADA 1XM2A 4OHEA 1BZJA 2NT7A 5BZXA 2Y96A 1PTVA 1C88A 2F6VA 1T4JA 2FJNA 4I8NA 2B3OA 1I57A 5LXQB 4PYHA 2BZLA 1ECVA 2MBCA 5GTJA 2CM2A 3QCGA 4RH9A 2VEWA 3RGOA 1EEOA 1V3AA 3GXHA 5J8RA 2QEPA 5MMZB 1I9SA 4J51A 2QBQA 4H34A 2NZ6A 3A5JA 4GFUA 1OHCA 4Z6BA 4NNDA 1QZ0A 2WGPA 3O4UA 3V0DA 3MMJA 1Q6TA 3M4UA 2I6JA 1PTYA 2J17A 1WAXA 5KA9A 1ZCLA 1OEUA 4GE6A 1Q6JA 2Q47A 3I36A 1L8GA 4YR8B 3ZM3A 3ZM2A 1YGUA 1WCHA 4YAAA 2P6XA 1NO6A 2I42A 4ERCA 2QDPA 1PTTA 4GFVA 4DGPA 1PTUA 4QUNA 5K22A 3O3LA 3V0FA 3S3FA 1PA9A 2CNIA 2VEUA 4OHIA 4RDDA 4ZRTA 1R6HA 2G59A 5IBMA 2VEXA 4AZ1A 2AZRA 3V0HA 3ZM0A 4TVVA 2IMGA 2CJZA 5AWXA 3F41A 2BGEA 5KA7A 5KA4A 3QCMA 1YZ4A 3V0GA 1G1GA 1T48A 3I80A 4OHHA 5K23A 4HRFA 1YN9A 2I6MA 4IKCA 2FH7A 1U24A 2OC3A 3D42A 3LJ8A 2CM8A 3F9AA 3V0IA 4NX8A 3I7ZA 2QDMA 2GP0A 5IBSA 2H4GA 5EHPA 2I75A 2AHSA 2GWOA 2F70A 3D1HA 2F6ZA 2H02A 1I9TA 1OETA 3SR9A 1GWZA 1MKPA 2NT2A 3QKQA 4ICZA 5KABA 2B4OA 1C85A 2HVLA 1OEOX 2CFVA 3EZZA 4PVGA 1G4US 4MBBA 3BM8A 3S3EA 1U26A 2NTAA 2BV5A 1G7FA 1LARA 2F6WA 3O4TA 1JF7A 5I6VA 3S4OA 1PYNA 3GXGA 3QCEA 3ZMQA 3QCJA 4H1OA 2J16A 1M3GA 2DXPA 4GE2A 1FPRA 4JNBA 3PS5A 1Q6SA 3V0EA 2B4SA 5K25A 2SHPA 4QUMA 2B07A 3D1QA 3BLTA 4RI4A 2I4GA 1YTWA 1YTSA 3QCIA 3QCBA 2CM3A 2CMAA 2HC2A 3MOWA 3BLUA 3OMHA 4GRZA 2B4UA 2HCMA 3QCNA 2CNFA 3MOZA 3O4SA 2Q05A 3QCFA 3N0AA 3NMEA 3F81A 2QCJA 3BRHA 1J4XA 3F9BA 3QCHA 2F6TA 2M3VA 4WU2A 1YGRA 1G1HA 4R0TA 2F6YA 3F99A 1G1FA 3OLRA 5KA1A 2G6ZA 4ZN5A 3SMEA 3CWEA 2QCTA 4RI5A 3ZMPA 1AAXA 4RH5A 4QBEA 4Y14A 1PA1A 4S0GA 1NL9A 2JJDA 2H4VA 5KA3A 2E0TA 2HY3A 4NYHA 2I4HA 3EU0A 1YFOA 3RZ2A 2CNHA 4KYQA 4JBCA 1WRMA 2PI7A 2ZMMA 2FJMA 1NWLA 1Q1MA 2I6OA 1NNYA 5KA2A 4OHLA 3AWFA 1Q6MA 3S3KA 5KAAA 1BZHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EB1 A;  1Q6N A;  2VEY A;  1X24 A;  3B7O A;  5EHR A;  4KYR A;  3A5K A;  1ZCK A;  2I3R A;  2CM7 A;  1C84 A;  3QCD A;  1G4W R;  1LYV A;  2CNE A;  2GJT A;  2C7S A;  4Y2E A;  4D3R A;  1OEM X;  4KI9 A;  3RGQ A;  1YTN A;  3D1O A;  4GRY A;  1D5R A;  1XBO A;  2NV5 A;  4JMJ A;  3AWG A;  2H03 A;  4BJO A;  2HNP A;  2RF6 A;  1EEN A;  2I5X A;  1QXK A;  5KAC A;  2ZN7 A;  2ESB A;  1NZ7 A;  2I6P A;  1BZC A;  2C46 A;  1YPT A;  2I3U A;  3S3H A;  4GS0 A;  3D9C A;  1L8K A;  3QKP A;  2A3K A;  2OOQ A;  4D3P A;  3QCC A;  1ONZ A;  2I4E A;  3QCK A;  4GE5 A;  1C83 A;  1ZZW A;  2CMB A;  2PSZ A;  5BUG A;  1VHR A;  2A8B A;  4RKK A;  2F6F A;  2HXP A;  2QDC A;  1SUG A;  2QBR A;  1A5Y A;  4NWG A;  5BZZ A;  2OZ5 A;  2OUD A;  5KA8 A;  4WTY A;  2HB1 A;  5M43 A;  2F46 A;  1ZC0 A;  1C86 A;  3EMU A;  4R0S A;  2BGD A;  1KAK A;  2I6I A;  2PBN A;  2BIJ A;  1OEV A;  2PQ5 A;  1RPM A;  1G7G A;  1RXD A;  1C87 A;  4GWF A;  2CNG A;  3O5X A;  1YWF A;  3AWE A;  3ZM1 A;  4HJQ A;  1PXH A;  5K9V A;  2Y2F A;  1P15 A;  2H4K A;  4DGX A;  4ZI4 A;  1ONY A;  3EAX A;  4BPC A;  1FPZ A;  1OHE A;  5K9W A;  4HJP A;  4NWF A;  1Q6P A;  2NLK A;  3S4E A;  4B04 A;  1GFY A;  2QBP A;  2P4D A;  1OES A;  5K24 A;  2YDU A;  2I1Y A;  4JMK A;  4R30 A;  3D44 A;  4RHG A;  2CMC A;  2B49 A;  4QAP A;  1XRI A;  1OHD A;  3QCL A;  5HDE A;  4WOH A;  1FQ1 A;  1U25 A;  2B4P A;  2F71 A;  2HNQ A;  2QBS A;  3U96 A;  5KA0 A;  3V0J A;  1LQF A;  4QAH A;  4OHD A;  5BX1 A;  1XXP A;  2J16 B;  3RO1 A;  2VEV A;  4D3Q A;  4QBW A;  1PH0 A;  1JLN A;  2HC1 A;  1KAV A;  2PT0 A;  3ZV2 A;  1NWE A;  1XXV A;  2PA5 A;  3H2X A;  2R0B A;  2H04 A;  3CM3 A;  1T49 A;  4WU3 A;  5KAD A;  1XM2 A;  4OHE A;  1BZJ A;  2NT7 A;  5BZX A;  2Y96 A;  1PTV A;  1C88 A;  2F6V A;  1T4J A;  2FJN A;  4I8N A;  2B3O A;  1I57 A;  5LXQ B;  4PYH A;  2BZL A;  1ECV A;  2MBC A;  5GTJ A;  2CM2 A;  3QCG A;  4RH9 A;  2VEW A;  3RGO A;  1EEO A;  1V3A A;  3GXH A;  5J8R A;  2QEP A;  5MMZ B;  1I9S A;  4J51 A;  2QBQ A;  4H34 A;  2NZ6 A;  3A5J A;  4GFU A;  1OHC A;  4Z6B A;  4NND A;  1QZ0 A;  2WGP A;  3O4U A;  3V0D A;  3MMJ A;  1Q6T A;  3M4U A;  2I6J A;  1PTY A;  2J17 A;  1WAX A;  5KA9 A;  1ZCL A;  1OEU A;  4GE6 A;  1Q6J A;  2Q47 A;  3I36 A;  1L8G A;  4YR8 B;  3ZM3 A;  3ZM2 A;  1YGU A;  1WCH A;  4YAA A;  2P6X A;  1NO6 A;  2I42 A;  4ERC A;  2QDP A;  1PTT A;  4GFV A;  4DGP A;  1PTU A;  4QUN A;  5K22 A;  3O3L A;  3V0F A;  3S3F A;  1PA9 A;  2CNI A;  2VEU A;  4OHI A;  4RDD A;  4ZRT A;  1R6H A;  2G59 A;  5IBM A;  2VEX A;  4AZ1 A;  2AZR A;  3V0H A;  3ZM0 A;  4TVV A;  2IMG A;  2CJZ A;  5AWX A;  3F41 A;  2BGE A;  5KA7 A;  5KA4 A;  3QCM A;  1YZ4 A;  3V0G A;  1G1G A;  1T48 A;  3I80 A;  4OHH A;  5K23 A;  4HRF A;  1YN9 A;  2I6M A;  4IKC A;  2FH7 A;  1U24 A;  2OC3 A;  3D42 A;  3LJ8 A;  2CM8 A;  3F9A A;  3V0I A;  4NX8 A;  3I7Z A;  2QDM A;  2GP0 A;  5IBS A;  2H4G A;  5EHP A;  2I75 A;  2AHS A;  2GWO A;  2F70 A;  3D1H A;  2F6Z A;  2H02 A;  1I9T A;  1OET A;  3SR9 A;  1GWZ A;  1MKP A;  2NT2 A;  3QKQ A;  4ICZ A;  5KAB A;  2B4O A;  1C85 A;  2HVL A;  1OEO X;  2CFV A;  3EZZ A;  4PVG A;  1G4U S;  4MBB A;  3BM8 A;  3S3E A;  1U26 A;  2NTA A;  2BV5 A;  1G7F A;  1LAR A;  2F6W A;  3O4T A;  1JF7 A;  5I6V A;  3S4O A;  1PYN A;  3GXG A;  3QCE A;  3ZMQ A;  3QCJ A;  4H1O A;  2J16 A;  1M3G A;  2DXP A;  4GE2 A;  1FPR A;  4JNB A;  3PS5 A;  1Q6S A;  3V0E A;  2B4S A;  5K25 A;  2SHP A;  4QUM A;  2B07 A;  3D1Q A;  3BLT A;  4RI4 A;  2I4G A;  1YTW A;  1YTS A;  3QCI A;  3QCB A;  2CM3 A;  2CMA A;  2HC2 A;  3MOW A;  3BLU A;  3OMH A;  4GRZ A;  2B4U A;  2HCM A;  3QCN A;  2CNF A;  3MOZ A;  3O4S A;  2Q05 A;  3QCF A;  3N0A A;  3NME A;  3F81 A;  2QCJ A;  3BRH A;  1J4X A;  3F9B A;  3QCH A;  2F6T A;  2M3V A;  4WU2 A;  1YGR A;  1G1H A;  4R0T A;  2F6Y A;  3F99 A;  1G1F A;  3OLR A;  5KA1 A;  2G6Z A;  4ZN5 A;  3SME A;  3CWE A;  2QCT A;  4RI5 A;  3ZMP A;  1AAX A;  4RH5 A;  4QBE A;  4Y14 A;  1PA1 A;  4S0G A;  1NL9 A;  2JJD A;  2H4V A;  5KA3 A;  2E0T A;  2HY3 A;  4NYH A;  2I4H A;  3EU0 A;  1YFO A;  3RZ2 A;  2CNH A;  4KYQ A;  4JBC A;  1WRM A;  2PI7 A;  2ZMM A;  2FJM A;  1NWL A;  1Q1M A;  2I6O A;  1NNY A;  5KA2 A;  4OHL A;  3AWF A;  1Q6M A;  3S3K A;  5KAA A;  1BZH A; 
#chains in the Genus database with same CATH topology
 3EB1 A;  1Q6N A;  2VEY A;  1X24 A;  3B7O A;  5EHR A;  4KYR A;  3A5K A;  1ZCK A;  2I3R A;  2CM7 A;  1C84 A;  1J6U A;  3QCD A;  1G4W R;  2Y68 A;  1LYV A;  2CNE A;  2GJT A;  2C7S A;  4Y2E A;  4D3R A;  1OEM X;  4KI9 A;  3RGQ A;  1YTN A;  3D1O A;  4GRY A;  1D5R A;  1XBO A;  2NV5 A;  4JMJ A;  3AWG A;  3N2A A;  2H03 A;  4BJO A;  2HNP A;  2RF6 A;  1UAG A;  2GC5 A;  1EEN A;  2I5X A;  1QXK A;  5KAC A;  2ZN7 A;  2ESB A;  3QCZ A;  1NZ7 A;  2I6P A;  1BZC A;  2C46 A;  1YPT A;  2I3U A;  3S3H A;  4GS0 A;  2AM1 A;  3D9C A;  1L8K A;  3QKP A;  2A3K A;  2JFH A;  2OOQ A;  4D3P A;  3QCC A;  3PYZ A;  1ONZ A;  2I4E A;  3QCK A;  4GE5 A;  1C83 A;  1ZZW A;  2CMB A;  2PSZ A;  5BUG A;  1VHR A;  2A8B A;  4RKK A;  1P3D A;  2F6F A;  3LK7 A;  2HXP A;  2QDC A;  1SUG A;  2QBR A;  1A5Y A;  4NWG A;  5BZZ A;  2OZ5 A;  2OUD A;  2JFG A;  5KA8 A;  4WTY A;  2HB1 A;  5M43 A;  1GQQ A;  2F46 A;  2GCB A;  4CVM A;  1ZC0 A;  1C86 A;  3EMU A;  4R0S A;  2BGD A;  1KAK A;  2I6I A;  2PBN A;  2VTD A;  2BIJ A;  1OEV A;  3ZM6 A;  2PQ5 A;  1RPM A;  1G7G A;  1RXD A;  1C87 A;  4GWF A;  2CNG A;  3O5X A;  1YWF A;  2XJA A;  3AWE A;  3ZM1 A;  4HJQ A;  1PXH A;  5K9V A;  2Y2F A;  1P15 A;  4BUB A;  2H4K A;  4DGX A;  4ZI4 A;  1ONY A;  3EAX A;  4BPC A;  2Y1O A;  1FPZ A;  1OHE A;  2AM2 A;  2GC6 A;  5K9W A;  4HJP A;  4NWF A;  1Q6P A;  2NLK A;  3S4E A;  4B04 A;  1GFY A;  2QBP A;  2P4D A;  4ZIY A;  1OES A;  5K24 A;  2YDU A;  2I1Y A;  4JMK A;  4R30 A;  3D44 A;  4RHG A;  2CMC A;  2B49 A;  4QAP A;  1XRI A;  1EEH A;  1OHD A;  3HN7 A;  3QCL A;  5HDE A;  4WOH A;  1FQ1 A;  2XPC A;  1U25 A;  2B4P A;  2F71 A;  3UAG A;  2HNQ A;  2QBS A;  3U96 A;  5KA0 A;  3V0J A;  1LQF A;  4QAH A;  4OHD A;  5BX1 A;  1XXP A;  2J16 B;  3RO1 A;  2JFF A;  2VEV A;  4QBW A;  2VOS A;  4D3Q A;  1PH0 A;  1JLN A;  2HC1 A;  1KAV A;  2PT0 A;  3ZV2 A;  1NWE A;  1XXV A;  2PA5 A;  3H2X A;  2R0B A;  3ZL8 A;  1FGS A;  2H04 A;  3CM3 A;  4QF5 A;  1T49 A;  4WU3 A;  5KAD A;  1XM2 A;  4OHE A;  1BZJ A;  2NT7 A;  1GQY A;  5BZX A;  2Y96 A;  1PTV A;  1C88 A;  3ZM5 A;  2F6V A;  1T4J A;  1W7K A;  2FJN A;  4I8N A;  2B3O A;  1I57 A;  5LXQ B;  4PYH A;  2BZL A;  1ECV A;  2MBC A;  5GTJ A;  4HV4 A;  2GCA A;  1E8C A;  2CM2 A;  4CVK A;  3QCG A;  4RH9 A;  2VEW A;  2UUO A;  3RGO A;  1JBV A;  1EEO A;  1V3A A;  3GXH A;  5J8R A;  2QEP A;  1GG4 A;  5MMZ B;  1I9S A;  4J51 A;  2QBQ A;  2VOR A;  4H34 A;  2UUP A;  2NZ6 A;  3A5J A;  4GFU A;  1OHC A;  4Z6B A;  2F00 A;  4NND A;  1QZ0 A;  2Y67 A;  2WGP A;  3O4U A;  3V0D A;  2VTE A;  3MMJ A;  1Q6T A;  3M4U A;  2I6J A;  1PTY A;  2J17 A;  1WAX A;  5KA9 A;  1ZCL A;  1OEU A;  2Y66 A;  4GE6 A;  1Q6J A;  2Q47 A;  2WJP A;  3I36 A;  1L8G A;  4YR8 B;  3ZM3 A;  4C13 A;  3ZM2 A;  1YGU A;  1WCH A;  4YAA A;  2P6X A;  1NO6 A;  2I42 A;  4ERC A;  2QDP A;  1PTT A;  4GFV A;  4DGP A;  1PTU A;  4QUN A;  5K22 A;  3O3L A;  3V0F A;  2X5O A;  3S3F A;  1PA9 A;  2CNI A;  2VEU A;  4OHI A;  4RDD A;  4ZRT A;  1R6H A;  2G59 A;  5IBM A;  2VEX A;  4AZ1 A;  2AZR A;  3V0H A;  3ZM0 A;  4TVV A;  2IMG A;  4QDI A;  2CJZ A;  5AWX A;  3F41 A;  2BGE A;  5KA7 A;  5KA4 A;  3QCM A;  1YZ4 A;  3V0G A;  1G1G A;  1T48 A;  3I80 A;  4OHH A;  5K23 A;  4HRF A;  4BUC A;  1YN9 A;  2I6M A;  4IKC A;  2FH7 A;  1U24 A;  1O5Z A;  2OC3 A;  5A5F A;  3D42 A;  3LJ8 A;  2CM8 A;  3F9A A;  3V0I A;  1P31 A;  4NX8 A;  1JBW A;  3I7Z A;  2QDM A;  2GP0 A;  2UAG A;  5IBS A;  2H4G A;  5EHP A;  2I75 A;  2AHS A;  2GWO A;  2F70 A;  3D1H A;  2F6Z A;  2H02 A;  1I9T A;  1OET A;  3SR9 A;  1GWZ A;  1MKP A;  2NT2 A;  3QKQ A;  4ICZ A;  5KAB A;  1E0D A;  3MVN A;  2B4O A;  1C85 A;  2HVL A;  1OEO X;  2CFV A;  3EZZ A;  4PVG A;  1G4U S;  4MBB A;  3BM8 A;  3S3E A;  1U26 A;  2NTA A;  2BV5 A;  1G7F A;  1LAR A;  2F6W A;  3O4T A;  5A5E A;  1JF7 A;  5I6V A;  3S4O A;  1PYN A;  3GXG A;  3QCE A;  3ZMQ A;  4C12 A;  3QCJ A;  4H1O A;  2J16 A;  1M3G A;  2DXP A;  4GE2 A;  1FPR A;  4JNB A;  2WTZ A;  3PS5 A;  1Q6S A;  3V0E A;  2B4S A;  5K25 A;  2SHP A;  4QUM A;  2B07 A;  3D1Q A;  3BLT A;  4RI4 A;  4UAG A;  2I4G A;  1YTW A;  1YTS A;  3QCI A;  3QCB A;  2CM3 A;  2CMA A;  2HC2 A;  3MOW A;  3BLU A;  3OMH A;  4GRZ A;  2B4U A;  2HCM A;  3QCN A;  2CNF A;  3MOZ A;  3O4S A;  2Q05 A;  3QCF A;  3N0A A;  3NME A;  3F81 A;  2QCJ A;  3BRH A;  1J4X A;  3F9B A;  3QCH A;  2F6T A;  2M3V A;  4WU2 A;  1YGR A;  1G1H A;  4R0T A;  2F6Y A;  3F99 A;  1G1F A;  3OLR A;  5KA1 A;  2G6Z A;  4ZN5 A;  3SME A;  3CWE A;  2QCT A;  4RI5 A;  3ZMP A;  1AAX A;  4RH5 A;  4QBE A;  4Y14 A;  1PA1 A;  4S0G A;  1NL9 A;  3NRS A;  2JJD A;  2H4V A;  5KA3 A;  2E0T A;  2HY3 A;  4NYH A;  2I4H A;  3EU0 A;  1YFO A;  3RZ2 A;  2CNH A;  4KYQ A;  4JBC A;  1WRM A;  2PI7 A;  2ZMM A;  2FJM A;  1NWL A;  1Q1M A;  2I6O A;  1NNY A;  5KA2 A;  4OHL A;  1W78 A;  3AWF A;  1Q6M A;  4CVL A;  3S3K A;  5KAA A;  1BZH A; 
#chains in the Genus database with same CATH homology
 3EB1 A;  1Q6N A;  2VEY A;  1X24 A;  3B7O A;  5EHR A;  4KYR A;  3A5K A;  1ZCK A;  2I3R A;  2CM7 A;  1C84 A;  3QCD A;  1G4W R;  1LYV A;  2CNE A;  2GJT A;  2C7S A;  4Y2E A;  4D3R A;  1OEM X;  4KI9 A;  3RGQ A;  1YTN A;  3D1O A;  4GRY A;  1D5R A;  1XBO A;  2NV5 A;  4JMJ A;  3AWG A;  2H03 A;  4BJO A;  2HNP A;  2RF6 A;  1EEN A;  2I5X A;  1QXK A;  5KAC A;  2ZN7 A;  2ESB A;  1NZ7 A;  2I6P A;  1BZC A;  2C46 A;  1YPT A;  2I3U A;  3S3H A;  4GS0 A;  3D9C A;  1L8K A;  3QKP A;  2A3K A;  2OOQ A;  4D3P A;  3QCC A;  1ONZ A;  2I4E A;  3QCK A;  4GE5 A;  1C83 A;  1ZZW A;  2CMB A;  2PSZ A;  5BUG A;  1VHR A;  2A8B A;  4RKK A;  2F6F A;  2HXP A;  2QDC A;  1SUG A;  2QBR A;  1A5Y A;  4NWG A;  5BZZ A;  2OZ5 A;  2OUD A;  5KA8 A;  4WTY A;  2HB1 A;  5M43 A;  2F46 A;  1ZC0 A;  1C86 A;  3EMU A;  4R0S A;  2BGD A;  1KAK A;  2I6I A;  2PBN A;  2BIJ A;  1OEV A;  2PQ5 A;  1RPM A;  1G7G A;  1RXD A;  1C87 A;  4GWF A;  2CNG A;  3O5X A;  1YWF A;  3AWE A;  3ZM1 A;  4HJQ A;  1PXH A;  5K9V A;  2Y2F A;  1P15 A;  2H4K A;  4DGX A;  4ZI4 A;  1ONY A;  3EAX A;  4BPC A;  1FPZ A;  1OHE A;  5K9W A;  4HJP A;  4NWF A;  1Q6P A;  2NLK A;  3S4E A;  4B04 A;  1GFY A;  2QBP A;  2P4D A;  1OES A;  5K24 A;  2YDU A;  2I1Y A;  4JMK A;  4R30 A;  3D44 A;  4RHG A;  2CMC A;  2B49 A;  4QAP A;  1XRI A;  1OHD A;  3QCL A;  5HDE A;  4WOH A;  1FQ1 A;  1U25 A;  2B4P A;  2F71 A;  2HNQ A;  2QBS A;  3U96 A;  5KA0 A;  3V0J A;  1LQF A;  4QAH A;  4OHD A;  5BX1 A;  1XXP A;  2J16 B;  3RO1 A;  2VEV A;  4D3Q A;  4QBW A;  1PH0 A;  1JLN A;  2HC1 A;  1KAV A;  2PT0 A;  3ZV2 A;  1NWE A;  1XXV A;  2PA5 A;  3H2X A;  2R0B A;  2H04 A;  3CM3 A;  1T49 A;  4WU3 A;  5KAD A;  1XM2 A;  4OHE A;  1BZJ A;  2NT7 A;  5BZX A;  2Y96 A;  1PTV A;  1C88 A;  2F6V A;  1T4J A;  2FJN A;  4I8N A;  2B3O A;  1I57 A;  5LXQ B;  4PYH A;  2BZL A;  1ECV A;  2MBC A;  5GTJ A;  2CM2 A;  3QCG A;  4RH9 A;  2VEW A;  3RGO A;  1EEO A;  1V3A A;  3GXH A;  5J8R A;  2QEP A;  5MMZ B;  1I9S A;  4J51 A;  2QBQ A;  4H34 A;  2NZ6 A;  3A5J A;  4GFU A;  1OHC A;  4Z6B A;  4NND A;  1QZ0 A;  2WGP A;  3O4U A;  3V0D A;  3MMJ A;  1Q6T A;  3M4U A;  2I6J A;  1PTY A;  2J17 A;  1WAX A;  5KA9 A;  1ZCL A;  1OEU A;  4GE6 A;  1Q6J A;  2Q47 A;  3I36 A;  1L8G A;  4YR8 B;  3ZM3 A;  3ZM2 A;  1YGU A;  1WCH A;  4YAA A;  2P6X A;  1NO6 A;  2I42 A;  4ERC A;  2QDP A;  1PTT A;  4GFV A;  4DGP A;  1PTU A;  4QUN A;  5K22 A;  3O3L A;  3V0F A;  3S3F A;  1PA9 A;  2CNI A;  2VEU A;  4OHI A;  4RDD A;  4ZRT A;  1R6H A;  2G59 A;  5IBM A;  2VEX A;  4AZ1 A;  2AZR A;  3V0H A;  3ZM0 A;  4TVV A;  2IMG A;  2CJZ A;  5AWX A;  3F41 A;  2BGE A;  5KA7 A;  5KA4 A;  3QCM A;  1YZ4 A;  3V0G A;  1G1G A;  1T48 A;  3I80 A;  4OHH A;  5K23 A;  4HRF A;  1YN9 A;  2I6M A;  4IKC A;  2FH7 A;  1U24 A;  2OC3 A;  3D42 A;  3LJ8 A;  2CM8 A;  3F9A A;  3V0I A;  4NX8 A;  3I7Z A;  2QDM A;  2GP0 A;  5IBS A;  2H4G A;  5EHP A;  2I75 A;  2AHS A;  2GWO A;  2F70 A;  3D1H A;  2F6Z A;  2H02 A;  1I9T A;  1OET A;  3SR9 A;  1GWZ A;  1MKP A;  2NT2 A;  3QKQ A;  4ICZ A;  5KAB A;  2B4O A;  1C85 A;  2HVL A;  1OEO X;  2CFV A;  3EZZ A;  4PVG A;  1G4U S;  4MBB A;  3BM8 A;  3S3E A;  1U26 A;  2NTA A;  2BV5 A;  1G7F A;  1LAR A;  2F6W A;  3O4T A;  1JF7 A;  5I6V A;  3S4O A;  1PYN A;  3GXG A;  3QCE A;  3ZMQ A;  3QCJ A;  4H1O A;  2J16 A;  1M3G A;  2DXP A;  4GE2 A;  1FPR A;  4JNB A;  3PS5 A;  1Q6S A;  3V0E A;  2B4S A;  5K25 A;  2SHP A;  4QUM A;  2B07 A;  3D1Q A;  3BLT A;  4RI4 A;  2I4G A;  1YTW A;  1YTS A;  3QCI A;  3QCB A;  2CM3 A;  2CMA A;  2HC2 A;  3MOW A;  3BLU A;  3OMH A;  4GRZ A;  2B4U A;  2HCM A;  3QCN A;  2CNF A;  3MOZ A;  3O4S A;  2Q05 A;  3QCF A;  3N0A A;  3NME A;  3F81 A;  2QCJ A;  3BRH A;  1J4X A;  3F9B A;  3QCH A;  2F6T A;  2M3V A;  4WU2 A;  1YGR A;  1G1H A;  4R0T A;  2F6Y A;  3F99 A;  1G1F A;  3OLR A;  5KA1 A;  2G6Z A;  4ZN5 A;  3SME A;  3CWE A;  2QCT A;  4RI5 A;  3ZMP A;  1AAX A;  4RH5 A;  4QBE A;  4Y14 A;  1PA1 A;  4S0G A;  1NL9 A;  2JJD A;  2H4V A;  5KA3 A;  2E0T A;  2HY3 A;  4NYH A;  2I4H A;  3EU0 A;  1YFO A;  3RZ2 A;  2CNH A;  4KYQ A;  4JBC A;  1WRM A;  2PI7 A;  2ZMM A;  2FJM A;  1NWL A;  1Q1M A;  2I6O A;  1NNY A;  5KA2 A;  4OHL A;  3AWF A;  1Q6M A;  3S3K A;  5KAA A;  1BZH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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